|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
197-801 |
1.96e-61 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 225.50 E-value: 1.96e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 197 LDLRGINFVGQLPLCFGNLNKLRFLDLSSNQLTGNIPPS-FSSLESLEYLSLSDNSFEGFFSLNPLTNLTKLKVfifssK 275
Cdd:PLN00113 74 IDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDiFTTSSSLRYLNLSNNNFTGSIPRGSIPNLETLDL-----S 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 276 DDMVQvkiestwqplfqlsvlvlrlcslEKIPNFLMYQKNLHVVDLSGNRISGIIPTWLlENNPELEVLQLKNNSFTiFQ 355
Cdd:PLN00113 149 NNMLS-----------------------GEIPNDIGSFSSLKVLDLGGNVLVGKIPNSL-TNLTSLEFLTLASNQLV-GQ 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 356 MPTSV---HNLQVLDFSENNIGGLFPDNFGRvLPNLVHMNGSNNGFQGNFPSSMGEMYNISFLDLSYNNLSGELPQSfVS 432
Cdd:PLN00113 204 IPRELgqmKSLKWIYLGYNNLSGEIPYEIGG-LTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPS-IF 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 433 SCFSLSILQLSHNKFSGHFLPRQTNFTSLIVLRINNNLFTGKIGVGLLTLVDLCILDMSNNFLEGELPPLLLVFEYLNFL 512
Cdd:PLN00113 282 SLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVL 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 513 DLSGNLLSGALPSHVSLDNVLF---LHNNNFTGPIPDTF--LGSIQILDLRNNKLSGNIPQ-FVDTQDISFLLLRGNSLT 586
Cdd:PLN00113 362 DLSTNNLTGEIPEGLCSSGNLFkliLFSNSLEGEIPKSLgaCRSLRRVRLQDNSFSGELPSeFTKLPLVYFLDISNNNLQ 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 587 GYIPSTLCEFSKMRLLDLSDNKLNGFIPScfnnlSFGLARKEeitnyyvavalesfylgfykstfvvenfRLDYSNyfei 666
Cdd:PLN00113 442 GRINSRKWDMPSLQMLSLARNKFFGGLPD-----SFGSKRLE----------------------------NLDLSR---- 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 667 dvkfatkqryDSYIGAFQFSEGTLNSMYGLDLSSNELSGVIPAELGDLFKLRALNLSHNFLSSHIPDSFSKLQDIESLDL 746
Cdd:PLN00113 485 ----------NQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDL 554
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1063737086 747 SYNMLQGSIPHQLTNLTSLAIFNVSYNNLSGIIPQGKQFNTFDENSYLGNPLLCG 801
Cdd:PLN00113 555 SQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
27-387 |
9.61e-22 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 98.85 E-value: 9.61e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 27 WENIKCNRTSRRLTGLSLYTSYYLEISLLNLSLLHPFEEVRSLDLSNSrlnglvddvegyKSLRRLRNLQILNFSSNEFN 106
Cdd:COG4886 59 DLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------------EELSNLTNLESLDLSGNQLT 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 107 nSIFPFLNAATSLTTLSLRRNNMyGPIPlKELKNLTNLELLDLSGNRIDgSMPvREFPYLKKLKALDLSSNGIySSMEwQ 186
Cdd:COG4886 127 -DLPEELANLTNLKELDLSNNQL-TDLP-EPLGNLTNLKSLDLSNNQLT-DLP-EELGNLTNLKELDLSNNQI-TDLP-E 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 187 VFCEMKNLQELDLRGiNFVGQLPLCFGNLNKLRFLDLSSNQLTGniPPSFSSLESLEYLSLSDNSFEGFFSLNPLTNLTK 266
Cdd:COG4886 200 PLGNLTNLEELDLSG-NQLTDLPEPLANLTNLETLDLSNNQLTD--LPELGNLTNLEELDLSNNQLTDLPPLANLTNLKT 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 267 LKVFIFSSKDDMVQVKIESTWQPLFQLSVLVLRLCSLEKIPNFLMYQKNLHVVDLSGNRISGIIPTWLLENNPELEVLQL 346
Cdd:COG4886 277 LDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLL 356
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1063737086 347 KNNSFTIFQMPTSVHNLQVLDFSENNIGGLFPDNFGRVLPN 387
Cdd:COG4886 357 NLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTT 397
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
42-267 |
5.67e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.46 E-value: 5.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 42 LSLYTSYYLEISLLNLSLLHPFEEVRSLDLSNSRLNGLVDDVEGYKSLRRLRNLQILNFSSNEFnnsifpfLNAATSLTT 121
Cdd:COG4886 45 LLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEE-------LSNLTNLES 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 122 LSLRRNNMyGPIPlKELKNLTNLELLDLSGNRIDgSMPvREFPYLKKLKALDLSSNGIySSMEwQVFCEMKNLQELDLRG 201
Cdd:COG4886 118 LDLSGNQL-TDLP-EELANLTNLKELDLSNNQLT-DLP-EPLGNLTNLKSLDLSNNQL-TDLP-EELGNLTNLKELDLSN 191
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063737086 202 iNFVGQLPLCFGNLNKLRFLDLSSNQLTgNIPPSFSSLESLEYLSLSDNSFEGFFSLNPLTNLTKL 267
Cdd:COG4886 192 -NQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEEL 255
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
58-228 |
1.61e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 57.37 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 58 SLLHPFEEVRSLDLSNSRLNGlvDDVEGY-KSLRRLRNLQILNFSSNEFNN----SIFPFLNAATSLTTLSLRRN--NMY 130
Cdd:cd00116 131 GLKDLPPALEKLVLGRNRLEG--ASCEALaKALRANRDLKELNLANNGIGDagirALAEGLKANCNLEVLDLNNNglTDE 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 131 GPIPLKE-LKNLTNLELLDLSGNRIdGSMPVREF-----PYLKKLKALDLSSNGIYSS---MEWQVFCEMKNLQELDLRG 201
Cdd:cd00116 209 GASALAEtLASLKSLEVLNLGDNNL-TDAGAAALasallSPNISLLTLSLSCNDITDDgakDLAEVLAEKESLLELDLRG 287
|
170 180 190
....*....|....*....|....*....|....
gi 1063737086 202 INF-------VGQLPLCFGnlNKLRFLDLSSNQL 228
Cdd:cd00116 288 NKFgeegaqlLAESLLEPG--NELESLWVKDDSF 319
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
66-159 |
4.80e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 56.75 E-value: 4.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 66 VRSLDLSNSRLNGLVDDvegykSLRRLRNLQILNFSSNEFNNSIFPFLNAATSLTTLSLRRNNMYGPIPlKELKNLTNLE 145
Cdd:PLN03150 420 IDGLGLDNQGLRGFIPN-----DISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIP-ESLGQLTSLR 493
|
90
....*....|....
gi 1063737086 146 LLDLSGNRIDGSMP 159
Cdd:PLN03150 494 ILNLNGNSLSGRVP 507
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
147-428 |
2.53e-07 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 53.51 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 147 LDLSGNRIDGSMPVREFPYLKKLKALDLSSNGIySSMEWQVFCEM----KNLQELDLRGIN------FVGQLPLCFGNLN 216
Cdd:cd00116 3 LSLKGELLKTERATELLPKLLCLQVLRLEGNTL-GEEAAKALASAlrpqPSLKELCLSLNEtgriprGLQSLLQGLTKGC 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 217 KLRFLDLSSNQLTGNIPPSFSSL---ESLEYLSLSDNSFEgffslnpltnltklkvfifsskDDMVQVKIESTWQPLFQL 293
Cdd:cd00116 82 GLQELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLG----------------------DRGLRLLAKGLKDLPPAL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 294 SVLVLRLCSL-----EKIPNFLMYQKNLHVVDLSGNRI--SGIIPTWL-LENNPELEVLQLKNNSFT------IFQMPTS 359
Cdd:cd00116 140 EKLVLGRNRLegascEALAKALRANRDLKELNLANNGIgdAGIRALAEgLKANCNLEVLDLNNNGLTdegasaLAETLAS 219
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063737086 360 VHNLQVLDFSENNIGGL----FPDNFGRVLPNLVHMNGSNN-----GFQgNFPSSMGEMYNISFLDLSYNNLSGELPQ 428
Cdd:cd00116 220 LKSLEVLNLGDNNLTDAgaaaLASALLSPNISLLTLSLSCNditddGAK-DLAEVLAEKESLLELDLRGNKFGEEGAQ 296
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
716-775 |
1.41e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 1.41e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 716 KLRALNLSHNFLSSHIPDSFSKLQDIESLDLSYNMLQGSIPHQLTNLTSLAIFNVSYNNL 775
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
142-201 |
3.41e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.43 E-value: 3.41e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 142 TNLELLDLSGNRIDgSMPVREFPYLKKLKALDLSSNGIySSMEWQVFCEMKNLQELDLRG 201
Cdd:pfam13855 1 PNLRSLDLSNNRLT-SLDDGAFKGLSNLKVLDLSNNLL-TTLSPGAFSGLPSLRYLDLSG 58
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
197-801 |
1.96e-61 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 225.50 E-value: 1.96e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 197 LDLRGINFVGQLPLCFGNLNKLRFLDLSSNQLTGNIPPS-FSSLESLEYLSLSDNSFEGFFSLNPLTNLTKLKVfifssK 275
Cdd:PLN00113 74 IDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDiFTTSSSLRYLNLSNNNFTGSIPRGSIPNLETLDL-----S 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 276 DDMVQvkiestwqplfqlsvlvlrlcslEKIPNFLMYQKNLHVVDLSGNRISGIIPTWLlENNPELEVLQLKNNSFTiFQ 355
Cdd:PLN00113 149 NNMLS-----------------------GEIPNDIGSFSSLKVLDLGGNVLVGKIPNSL-TNLTSLEFLTLASNQLV-GQ 203
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 356 MPTSV---HNLQVLDFSENNIGGLFPDNFGRvLPNLVHMNGSNNGFQGNFPSSMGEMYNISFLDLSYNNLSGELPQSfVS 432
Cdd:PLN00113 204 IPRELgqmKSLKWIYLGYNNLSGEIPYEIGG-LTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPS-IF 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 433 SCFSLSILQLSHNKFSGHFLPRQTNFTSLIVLRINNNLFTGKIGVGLLTLVDLCILDMSNNFLEGELPPLLLVFEYLNFL 512
Cdd:PLN00113 282 SLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVL 361
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 513 DLSGNLLSGALPSHVSLDNVLF---LHNNNFTGPIPDTF--LGSIQILDLRNNKLSGNIPQ-FVDTQDISFLLLRGNSLT 586
Cdd:PLN00113 362 DLSTNNLTGEIPEGLCSSGNLFkliLFSNSLEGEIPKSLgaCRSLRRVRLQDNSFSGELPSeFTKLPLVYFLDISNNNLQ 441
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 587 GYIPSTLCEFSKMRLLDLSDNKLNGFIPScfnnlSFGLARKEeitnyyvavalesfylgfykstfvvenfRLDYSNyfei 666
Cdd:PLN00113 442 GRINSRKWDMPSLQMLSLARNKFFGGLPD-----SFGSKRLE----------------------------NLDLSR---- 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 667 dvkfatkqryDSYIGAFQFSEGTLNSMYGLDLSSNELSGVIPAELGDLFKLRALNLSHNFLSSHIPDSFSKLQDIESLDL 746
Cdd:PLN00113 485 ----------NQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDL 554
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 1063737086 747 SYNMLQGSIPHQLTNLTSLAIFNVSYNNLSGIIPQGKQFNTFDENSYLGNPLLCG 801
Cdd:PLN00113 555 SQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLPSTGAFLAINASAVAGNIDLCG 609
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
27-387 |
9.61e-22 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 98.85 E-value: 9.61e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 27 WENIKCNRTSRRLTGLSLYTSYYLEISLLNLSLLHPFEEVRSLDLSNSrlnglvddvegyKSLRRLRNLQILNFSSNEFN 106
Cdd:COG4886 59 DLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN------------EELSNLTNLESLDLSGNQLT 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 107 nSIFPFLNAATSLTTLSLRRNNMyGPIPlKELKNLTNLELLDLSGNRIDgSMPvREFPYLKKLKALDLSSNGIySSMEwQ 186
Cdd:COG4886 127 -DLPEELANLTNLKELDLSNNQL-TDLP-EPLGNLTNLKSLDLSNNQLT-DLP-EELGNLTNLKELDLSNNQI-TDLP-E 199
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 187 VFCEMKNLQELDLRGiNFVGQLPLCFGNLNKLRFLDLSSNQLTGniPPSFSSLESLEYLSLSDNSFEGFFSLNPLTNLTK 266
Cdd:COG4886 200 PLGNLTNLEELDLSG-NQLTDLPEPLANLTNLETLDLSNNQLTD--LPELGNLTNLEELDLSNNQLTDLPPLANLTNLKT 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 267 LKVFIFSSKDDMVQVKIESTWQPLFQLSVLVLRLCSLEKIPNFLMYQKNLHVVDLSGNRISGIIPTWLLENNPELEVLQL 346
Cdd:COG4886 277 LDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLL 356
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1063737086 347 KNNSFTIFQMPTSVHNLQVLDFSENNIGGLFPDNFGRVLPN 387
Cdd:COG4886 357 NLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTT 397
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
42-267 |
5.67e-20 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 93.46 E-value: 5.67e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 42 LSLYTSYYLEISLLNLSLLHPFEEVRSLDLSNSRLNGLVDDVEGYKSLRRLRNLQILNFSSNEFnnsifpfLNAATSLTT 121
Cdd:COG4886 45 LLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEE-------LSNLTNLES 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 122 LSLRRNNMyGPIPlKELKNLTNLELLDLSGNRIDgSMPvREFPYLKKLKALDLSSNGIySSMEwQVFCEMKNLQELDLRG 201
Cdd:COG4886 118 LDLSGNQL-TDLP-EELANLTNLKELDLSNNQLT-DLP-EPLGNLTNLKSLDLSNNQL-TDLP-EELGNLTNLKELDLSN 191
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063737086 202 iNFVGQLPLCFGNLNKLRFLDLSSNQLTgNIPPSFSSLESLEYLSLSDNSFEGFFSLNPLTNLTKL 267
Cdd:COG4886 192 -NQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQLTDLPELGNLTNLEEL 255
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
92-468 |
3.01e-19 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 91.15 E-value: 3.01e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 92 LRNLQILNFSSNEFNNSIFPFLNAATSLTTLSLRRNNMYGPIPLKELKNLTNLELLDLSGNRIDGSMPVREFPYLKKLKA 171
Cdd:COG4886 21 LTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 172 LDLSSNgiyssmewQVFCEMKNLQELDLRGiNFVGQLPLCFGNLNKLRFLDLSSNQLTgNIPPSFSSLESLEYLSLSDNS 251
Cdd:COG4886 101 LDLSGN--------EELSNLTNLESLDLSG-NQLTDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQ 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 252 FEGFFSlnPLTNLTKLKVFIFSSKddmvQVK-IESTWQPLFQLSVLVLRLCSLEKIPNFLMYQKNLHVVDLSGNRISGII 330
Cdd:COG4886 171 LTDLPE--ELGNLTNLKELDLSNN----QITdLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 331 PtwlLENNPELEVLQLKNNSFTIFQMPTSVHNLQVLDFSENNIGGLFPDNFGRVLPNLVHMNGSNNGFQGNFPSSMGEMY 410
Cdd:COG4886 245 E---LGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLT 321
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 1063737086 411 NISFLDLSYNNLSGELPQSFVSSCFSLSILQLSHNKFSGHFLPRQTNFTSLIVLRINN 468
Cdd:COG4886 322 TLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATL 379
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
695-808 |
6.11e-19 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 91.80 E-value: 6.11e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 695 GLDLSSNELSGVIPAELGDLFKLRALNLSHNFLSSHIPDSFSKLQDIESLDLSYNMLQGSIPHQLTNLTSLAIFNVSYNN 774
Cdd:PLN03150 422 GLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNS 501
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1063737086 775 LSGIIP--------QGKQFNTFDensylgNPLLCGPPTDTSC 808
Cdd:PLN03150 502 LSGRVPaalggrllHRASFNFTD------NAGLCGIPGLRAC 537
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
24-435 |
2.99e-18 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 88.07 E-value: 2.99e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 24 CCQWENIKCNRTSRRLTGLSLYTSYYLEISLLNLSLLHPFEEVRSLDLSNSRLNGLVDDVEGYKSLRRLRNLQILNFSSN 103
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 104 EFNNSIFPF--LNAATSLTTLSLRRNNmygpiPLKELKNLTNlelLDLSGNRIDgSMPVrEFPYLKKLKALDLSSNGIYS 181
Cdd:COG4886 81 LLSLLLLGLtdLGDLTNLTELDLSGNE-----ELSNLTNLES---LDLSGNQLT-DLPE-ELANLTNLKELDLSNNQLTD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 182 SMEwqVFCEMKNLQELDLRGiNFVGQLPLCFGNLNKLRFLDLSSNQLTgNIPPSFSSLESLEYLSLSDNSFEGFFSlnPL 261
Cdd:COG4886 151 LPE--PLGNLTNLKSLDLSN-NQLTDLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTDLPE--PL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 262 TNLTKLKvfifsskddmvqvkiestwqplfqlsVLVLRLCSLEKIPNfLMYQKNLHVVDLSGNRISGIIPtwlLENNPEL 341
Cdd:COG4886 225 ANLTNLE--------------------------TLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDLPP---LANLTNL 274
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 342 EVLQLKNNSFTIFQMPTSVHNLQVLDFSENNIGGLFPDNFGRVLPNLVHMNGSNNGFQGNFPSSMGEMYNISFLDLSYNN 421
Cdd:COG4886 275 KTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLL 354
|
410
....*....|....
gi 1063737086 422 LSGELPQSFVSSCF 435
Cdd:COG4886 355 LLNLLSLLLTLLLT 368
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
575-780 |
2.73e-16 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 83.74 E-value: 2.73e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 575 ISFLLLRGNSLTGYIPSTLCEFSKMRLLDLSDNKLNGFIPSCFNNLSFGLARkeeitnyyvavalesfylgfykstfvve 654
Cdd:PLN00113 71 VVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSSSLRY---------------------------- 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 655 nfrLDYSNyfeidvkfatkqryDSYIGAFqfSEGTLNSMYGLDLSSNELSGVIPAELGDLFKLRALNLSHNFLSSHIPDS 734
Cdd:PLN00113 123 ---LNLSN--------------NNFTGSI--PRGSIPNLETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNS 183
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 1063737086 735 FSKLQDIESLDLSYNMLQGSIPHQLTNLTSLAIFNVSYNNLSGIIP 780
Cdd:PLN00113 184 LTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIP 229
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
696-778 |
5.60e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 62.26 E-value: 5.60e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 696 LDLSSNELSGvIPAELGDLFKLRALNLSHNFLSShIPDSFSKLQDIESLDLSYNMLQgSIPHQLTNLTSLAIFNVSYNNL 775
Cdd:COG4886 164 LDLSNNQLTD-LPEELGNLTNLKELDLSNNQITD-LPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQL 240
|
...
gi 1063737086 776 SGI 778
Cdd:COG4886 241 TDL 243
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
690-778 |
6.97e-10 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 62.53 E-value: 6.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 690 LNSMYGLDLSSNELSGVIPAELGDLFKLRALNLSHNFLSSHIPDSFSKLQDIESLDLSYNMLQGSIPHQL-TNLTSLAIF 768
Cdd:PLN03150 441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAALgGRLLHRASF 520
|
90
....*....|.
gi 1063737086 769 NVSYN-NLSGI 778
Cdd:PLN03150 521 NFTDNaGLCGI 531
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
456-778 |
2.51e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 60.33 E-value: 2.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 456 TNFTSLIVLRINNNLFTGKIGVGLLTLVDLCILDMSNNFLEGELPPLLLVFEYLNFLDLSGNLLSGALPSHVSLDNVLFL 535
Cdd:COG4886 19 ELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNL 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 536 HNNNFTGPIPDTFLGSIQILDLRNNKLSGNIPQFVDTQDISFLLLRGNSLTgYIPSTLCEFSKMRLLDLSDNKLNGfIPS 615
Cdd:COG4886 99 TELDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQLTD-LPE 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 616 CFNNLSfglarkeeitnyyvavALESfylgfykstfvvenfrldysnyfeidvkfatkqrydsyigafqfsegtlnsmyg 695
Cdd:COG4886 177 ELGNLT----------------NLKE------------------------------------------------------ 186
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 696 LDLSSNELSgVIPAELGDLFKLRALNLSHNFLSShIPDSFSKLQDIESLDLSYNMLQgSIPhQLTNLTSLAIFNVSYNNL 775
Cdd:COG4886 187 LDLSNNQIT-DLPEPLGNLTNLEELDLSGNQLTD-LPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQL 262
|
...
gi 1063737086 776 SGI 778
Cdd:COG4886 263 TDL 265
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
244-680 |
4.39e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 59.56 E-value: 4.39e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 244 YLSLSDNSFEGFFSLNPLTNLTKLKVFIFSSKDDMVQVKIESTWQPLFQLSVLVLRLCSLEKIPNFLMYQKNLHVVDLSG 323
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 324 NRISGIIPTWLLENNPELEVLQLKNNSFTifqmpTSVHNLQVLDFSENNIGGLfPDNFGRvLPNLVHMNGSNNGFQgNFP 403
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNEEL-----SNLTNLESLDLSGNQLTDL-PEELAN-LTNLKELDLSNNQLT-DLP 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 404 SSMGEMYNISFLDLSYNNLSgELPQSFvSSCFSLSILQLSHNKFSghFLPRQ-TNFTSLIVLRINNNLftgkigvglLTL 482
Cdd:COG4886 153 EPLGNLTNLKSLDLSNNQLT-DLPEEL-GNLTNLKELDLSNNQIT--DLPEPlGNLTNLEELDLSGNQ---------LTD 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 483 VDLCILDMSNnflegelpplllvfeyLNFLDLSGNLLSgALPSHVSLDN--VLFLHNNNFTGPIPDTFLGSIQILDLRNN 560
Cdd:COG4886 220 LPEPLANLTN----------------LETLDLSNNQLT-DLPELGNLTNleELDLSNNQLTDLPPLANLTNLKTLDLSNN 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 561 KLSGNIPQFVDTQDISFLLLRGNSLTGYIPSTLCEFSKMRLLDLSDNKLNGFIPSCFNNLSFGLARKEEITNYYVAVALE 640
Cdd:COG4886 283 QLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLL 362
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 1063737086 641 SFYLGFYKSTFVVENFRLDYSNYFEIDVKFATKQRYDSYI 680
Cdd:COG4886 363 LTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLL 402
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
191-254 |
1.55e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 58.29 E-value: 1.55e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063737086 191 MKNLQELDLRGINFVGQLPLCFGNLNKLRFLDLSSNQLTGNIPPSFSSLESLEYLSLSDNSFEG 254
Cdd:PLN03150 441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSG 504
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
58-228 |
1.61e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 57.37 E-value: 1.61e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 58 SLLHPFEEVRSLDLSNSRLNGlvDDVEGY-KSLRRLRNLQILNFSSNEFNN----SIFPFLNAATSLTTLSLRRN--NMY 130
Cdd:cd00116 131 GLKDLPPALEKLVLGRNRLEG--ASCEALaKALRANRDLKELNLANNGIGDagirALAEGLKANCNLEVLDLNNNglTDE 208
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 131 GPIPLKE-LKNLTNLELLDLSGNRIdGSMPVREF-----PYLKKLKALDLSSNGIYSS---MEWQVFCEMKNLQELDLRG 201
Cdd:cd00116 209 GASALAEtLASLKSLEVLNLGDNNL-TDAGAAALasallSPNISLLTLSLSCNDITDDgakDLAEVLAEKESLLELDLRG 287
|
170 180 190
....*....|....*....|....*....|....
gi 1063737086 202 INF-------VGQLPLCFGnlNKLRFLDLSSNQL 228
Cdd:cd00116 288 NKFgeegaqlLAESLLEPG--NELESLWVKDDSF 319
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
371-449 |
3.29e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 57.13 E-value: 3.29e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 371 NNIG--GLFPDNFGRvLPNLVHMNGSNNGFQGNFPSSMGEMYNISFLDLSYNNLSGELPQSfVSSCFSLSILQLSHNKFS 448
Cdd:PLN03150 426 DNQGlrGFIPNDISK-LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPES-LGQLTSLRILNLNGNSLS 503
|
.
gi 1063737086 449 G 449
Cdd:PLN03150 504 G 504
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
66-159 |
4.80e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 56.75 E-value: 4.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 66 VRSLDLSNSRLNGLVDDvegykSLRRLRNLQILNFSSNEFNNSIFPFLNAATSLTTLSLRRNNMYGPIPlKELKNLTNLE 145
Cdd:PLN03150 420 IDGLGLDNQGLRGFIPN-----DISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIP-ESLGQLTSLR 493
|
90
....*....|....
gi 1063737086 146 LLDLSGNRIDGSMP 159
Cdd:PLN03150 494 ILNLNGNSLSGRVP 507
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
681-734 |
6.21e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 56.36 E-value: 6.21e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 1063737086 681 GAFQFSEGTLNSMYGLDLSSNELSGVIPAELGDLFKLRALNLSHNFLSSHIPDS 734
Cdd:PLN03150 456 GNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAA 509
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
315-735 |
8.79e-08 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 55.32 E-value: 8.79e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 315 NLHVVDLSGNRISGIIPTWLLENNPELEVLQLKNNSFTIFQMPTSVHNLQVLDFSENNIGGLFPDNFGRVLPNLVHMNGS 394
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 395 NNGFQGNFPSSMGEMYNISFLDLSYNNLSGELPQsfvsscfsLSILQLSHNKFSGhfLPRQ-TNFTSLIVLRINNNLFTg 473
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTN--------LESLDLSGNQLTD--LPEElANLTNLKELDLSNNQLT- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 474 KIGVGLLTLVDLCILDMSNNFLEGELPPLLLvFEYLNFLDLSGNLLSgALPSHVS-LDN--VLFLHNNNFTgPIPDTF-- 548
Cdd:COG4886 150 DLPEPLGNLTNLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNNQIT-DLPEPLGnLTNleELDLSGNQLT-DLPEPLan 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 549 LGSIQILDLRNNKLSgNIPQFVDTQDISFLLLRGNSLTGYipSTLCEFSKMRLLDLSDNKLNGFIPSCFNNLSFGLARKE 628
Cdd:COG4886 227 LTNLETLDLSNNQLT-DLPELGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLL 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 629 EITNYYVAVALESFYLGFYKSTFVVENFRLDYSNYFEIDVKFATKQRYDSYIGAFQFSEGTLNSMYGLDLSSNELSGVIP 708
Cdd:COG4886 304 LLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383
|
410 420
....*....|....*....|....*..
gi 1063737086 709 AELGDLFKLRALNLSHNFLSSHIPDSF 735
Cdd:COG4886 384 LLLLTLLLLLLTTTAGVLLLTLALLDA 410
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
197-267 |
1.61e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 55.21 E-value: 1.61e-07
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1063737086 197 LDLRGINfvGQLPLCFGNLNKLRFLDLSSNQLTGNIPPSFSSLESLEYLSLSDNSFEGFF--SLNPLTNLTKL 267
Cdd:PLN03150 425 LDNQGLR--GFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIpeSLGQLTSLRIL 495
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
147-428 |
2.53e-07 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 53.51 E-value: 2.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 147 LDLSGNRIDGSMPVREFPYLKKLKALDLSSNGIySSMEWQVFCEM----KNLQELDLRGIN------FVGQLPLCFGNLN 216
Cdd:cd00116 3 LSLKGELLKTERATELLPKLLCLQVLRLEGNTL-GEEAAKALASAlrpqPSLKELCLSLNEtgriprGLQSLLQGLTKGC 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 217 KLRFLDLSSNQLTGNIPPSFSSL---ESLEYLSLSDNSFEgffslnpltnltklkvfifsskDDMVQVKIESTWQPLFQL 293
Cdd:cd00116 82 GLQELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLG----------------------DRGLRLLAKGLKDLPPAL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 294 SVLVLRLCSL-----EKIPNFLMYQKNLHVVDLSGNRI--SGIIPTWL-LENNPELEVLQLKNNSFT------IFQMPTS 359
Cdd:cd00116 140 EKLVLGRNRLegascEALAKALRANRDLKELNLANNGIgdAGIRALAEgLKANCNLEVLDLNNNGLTdegasaLAETLAS 219
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063737086 360 VHNLQVLDFSENNIGGL----FPDNFGRVLPNLVHMNGSNN-----GFQgNFPSSMGEMYNISFLDLSYNNLSGELPQ 428
Cdd:cd00116 220 LKSLEVLNLGDNNLTDAgaaaLASALLSPNISLLTLSLSCNditddGAK-DLAEVLAEKESLLELDLRGNKFGEEGAQ 296
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
361-429 |
3.54e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 54.05 E-value: 3.54e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063737086 361 HNLQVLDFSENNIGGLFPDNFGRVlPNLVHMNGSNNGFQGNFPSSMGEMYNISFLDLSYNNLSGELPQS 429
Cdd:PLN03150 442 RHLQSINLSGNSIRGNIPPSLGSI-TSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVPAA 509
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
533-615 |
7.40e-07 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 52.90 E-value: 7.40e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 533 LFLHNNNFTGPIPDTF--LGSIQILDLRNNKLSGNIPQFVDT-QDISFLLLRGNSLTGYIPSTLCEFSKMRLLDLSDNKL 609
Cdd:PLN03150 423 LGLDNQGLRGFIPNDIskLRHLQSINLSGNSIRGNIPPSLGSiTSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502
|
....*.
gi 1063737086 610 NGFIPS 615
Cdd:PLN03150 503 SGRVPA 508
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
716-775 |
1.41e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.98 E-value: 1.41e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 716 KLRALNLSHNFLSSHIPDSFSKLQDIESLDLSYNMLQGSIPHQLTNLTSLAIFNVSYNNL 775
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
512-593 |
5.88e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 49.81 E-value: 5.88e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 512 LDLSGNLLSGALPSHVS----LDNvLFLHNNNFTGPIPDTF--LGSIQILDLRNNKLSGNIPQFV-DTQDISFLLLRGNS 584
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISklrhLQS-INLSGNSIRGNIPPSLgsITSLEVLDLSYNSFNGSIPESLgQLTSLRILNLNGNS 501
|
....*....
gi 1063737086 585 LTGYIPSTL 593
Cdd:PLN03150 502 LSGRVPAAL 510
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
89-250 |
8.12e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 47.86 E-value: 8.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 89 LRRLRNLQILNFssneFNNSI--FPFLNAATSLTTLSLRRNNMYgpiPLKELKNLTNLELLDLSGNRIdgSMpVREFPYL 166
Cdd:cd21340 20 LSLCKNLKVLYL----YDNKItkIENLEFLTNLTHLYLQNNQIE---KIENLENLVNLKKLYLGGNRI--SV-VEGLENL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 167 KKLKALDLSSNGIYS--SMEWQVFCEM---KNLQELDLRGINFVGQLPLcfGNLNKLRFLDLSSNQLT--GNIPPSFSSL 239
Cdd:cd21340 90 TNLEELHIENQRLPPgeKLTFDPRSLAalsNSLRVLNISGNNIDSLEPL--APLRNLEQLDASNNQISdlEELLDLLSSW 167
|
170
....*....|.
gi 1063737086 240 ESLEYLSLSDN 250
Cdd:cd21340 168 PSLRELDLTGN 178
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
66-229 |
3.35e-05 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 47.09 E-value: 3.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 66 VRSLDLSNsrlNGLVDD--VEGYKSLRRLRNLQILNFSSNEFNN----SIFPFLNAATSLTTLSLRRNNMYGP--IPLKE 137
Cdd:COG5238 238 LTTLDLSN---NQIGDEgvIALAEALKNNTTVETLYLSGNQIGAegaiALAKALQGNTTLTSLDLSVNRIGDEgaIALAE 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 138 -LKNLTNLELLDLSGNRIDGSMPVREFPYLKK---LKALDLSSNGIY-SSMEwqVFCEM----KNLQELDLRG--INFVG 206
Cdd:COG5238 315 gLQGNKTLHTLNLAYNGIGAQGAIALAKALQEnttLHSLDLSDNQIGdEGAI--ALAKYlegnTTLRELNLGKnnIGKQG 392
|
170 180
....*....|....*....|....
gi 1063737086 207 QLPLCFG-NLNKLRFLDLSSNQLT 229
Cdd:COG5238 393 AEALIDAlQTNRLHTLILDGNLIG 416
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
696-751 |
5.22e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.74 E-value: 5.22e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1063737086 696 LDLSSNELSGVIPAELGDLFKLRALNLSHNFLSSHIPDSFSKLQDIESLDLSYNML 751
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
193-252 |
5.87e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.74 E-value: 5.87e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 193 NLQELDLRGINFVGQLPLCFGNLNKLRFLDLSSNQLTGNIPPSFSSLESLEYLSLSDNSF 252
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
147-235 |
6.80e-05 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 46.73 E-value: 6.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 147 LDLSGNRIDGSMPvREFPYLKKLKALDLSSNGIYSSMEWQvFCEMKNLQELDLRGINFVGQLPLCFGNLNKLRFLDLSSN 226
Cdd:PLN03150 423 LGLDNQGLRGFIP-NDISKLRHLQSINLSGNSIRGNIPPS-LGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGN 500
|
....*....
gi 1063737086 227 QLTGNIPPS 235
Cdd:PLN03150 501 SLSGRVPAA 509
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
552-621 |
1.35e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 45.58 E-value: 1.35e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1063737086 552 IQILDLRNNKLSG----NIPQFVDTQDISfllLRGNSLTGYIPSTLCEFSKMRLLDLSDNKLNGFIPSCFNNLS 621
Cdd:PLN03150 420 IDGLGLDNQGLRGfipnDISKLRHLQSIN---LSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLT 490
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
716-801 |
1.95e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.22 E-value: 1.95e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 716 KLRALNLSHNFLSSHIPDSFSKLQDIESLDLSYNMLQGSIPHQLTNLT-SLAIFNVSYNNLSGIIPQGKQFN--TFDens 792
Cdd:PLN00113 70 RVVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTSsSLRYLNLSNNNFTGSIPRGSIPNleTLD--- 146
|
....*....
gi 1063737086 793 yLGNPLLCG 801
Cdd:PLN00113 147 -LSNNMLSG 154
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
395-527 |
2.65e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 44.81 E-value: 2.65e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 395 NNGFQGNFPSSMGEMYNISFLDLSYNNLSGELPQSFvSSCFSLSILQLSHNKFSGHfLPRQtnftslivlrinnnlftgk 474
Cdd:PLN03150 427 NQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSL-GSITSLEVLDLSYNSFNGS-IPES------------------- 485
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 1063737086 475 igVGLLTLvdlcildmsnnflegelpplllvfeyLNFLDLSGNLLSGALPSHV 527
Cdd:PLN03150 486 --LGQLTS--------------------------LRILNLNGNSLSGRVPAAL 510
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
142-201 |
3.41e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.43 E-value: 3.41e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 142 TNLELLDLSGNRIDgSMPVREFPYLKKLKALDLSSNGIySSMEWQVFCEMKNLQELDLRG 201
Cdd:pfam13855 1 PNLRSLDLSNNRLT-SLDDGAFKGLSNLKVLDLSNNLL-TTLSPGAFSGLPSLRYLDLSG 58
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
306-407 |
5.49e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 43.65 E-value: 5.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 306 IPNFLMYQKNLHVVDLSGNRISGIIPTWLlennpelevlqlknnsftifqmpTSVHNLQVLDFSENNIGGLFPDNFGRvL 385
Cdd:PLN03150 434 IPNDISKLRHLQSINLSGNSIRGNIPPSL-----------------------GSITSLEVLDLSYNSFNGSIPESLGQ-L 489
|
90 100
....*....|....*....|..
gi 1063737086 386 PNLVHMNGSNNGFQGNFPSSMG 407
Cdd:PLN03150 490 TSLRILNLNGNSLSGRVPAALG 511
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
37-276 |
9.57e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 42.47 E-value: 9.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 37 RRLTGLSLYTSYYLEISLLNLSLLHPFEE-----VRSLDLSNSRLnGLVDDVEGYKSLRRLRNLQILNFSSNEFNNSIFP 111
Cdd:COG5238 148 KDPLGGNAVHLLGLAARLGLLAAISMAKAlqnnsVETVYLGCNQI-GDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAE 226
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 112 FLNAA----TSLTTLSLRRNNM--YGPIPLKE-LKNLTNLELLDLSGNRIDGSMPVREFPYLKK---LKALDLSSNGIyS 181
Cdd:COG5238 227 ILAEAlkgnKSLTTLDLSNNQIgdEGVIALAEaLKNNTTVETLYLSGNQIGAEGAIALAKALQGnttLTSLDLSVNRI-G 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 182 SMEWQVFCEM----KNLQELDL--RGINFVGQLPLcFGNLNKLR---FLDLSSNQLTGN----IPPSFSSLESLEYLSLS 248
Cdd:COG5238 306 DEGAIALAEGlqgnKTLHTLNLayNGIGAQGAIAL-AKALQENTtlhSLDLSDNQIGDEgaiaLAKYLEGNTTLRELNLG 384
|
250 260 270
....*....|....*....|....*....|
gi 1063737086 249 DN--SFEGFFSLNPLTNLTKLKVFIFSSKD 276
Cdd:COG5238 385 KNniGKQGAEALIDALQTNRLHTLILDGNL 414
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
314-425 |
1.50e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 42.08 E-value: 1.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 314 KNLHVVDLSGNRIS--GIIPTW-LLENNPELEVLQLKNNSFT------IFQMPTSVHNLQVLDFSENNIGGLFPDNFGRV 384
Cdd:COG5238 180 NSVETVYLGCNQIGdeGIEELAeALTQNTTVTTLWLKRNPIGdegaeiLAEALKGNKSLTTLDLSNNQIGDEGVIALAEA 259
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 1063737086 385 LPN---LVHMNGSNNGFQGNFPSSMGEMY----NISFLDLSYNNLSGE 425
Cdd:COG5238 260 LKNnttVETLYLSGNQIGAEGAIALAKALqgntTLTSLDLSVNRIGDE 307
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
117-179 |
1.60e-03 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 37.50 E-value: 1.60e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1063737086 117 TSLTTLSLRRNNMYGpIPLKELKNLTNLELLDLSGNRIDGSMPvREFPYLKKLKALDLSSNGI 179
Cdd:pfam13855 1 PNLRSLDLSNNRLTS-LDDGAFKGLSNLKVLDLSNNLLTTLSP-GAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
303-445 |
2.79e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 40.15 E-value: 2.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 303 LEKIPNFLMYqKNLHVVDLSGNRISGIIPtwlLENNPELEVLQLKNNSFTIFQMPTSVHNLQVLDFSENNIG---GL--- 376
Cdd:cd21340 14 ITKIDNLSLC-KNLKVLYLYDNKITKIEN---LEFLTNLTHLYLQNNQIEKIENLENLVNLKKLYLGGNRISvveGLenl 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 377 --------------------F-PDNFGRVLPNLVHMNGSNNGFQgnFPSSMGEMYNISFLDLSYNNLS--GELpQSFVSS 433
Cdd:cd21340 90 tnleelhienqrlppgekltFdPRSLAALSNSLRVLNISGNNID--SLEPLAPLRNLEQLDASNNQISdlEEL-LDLLSS 166
|
170
....*....|..
gi 1063737086 434 CFSLSILQLSHN 445
Cdd:cd21340 167 WPSLRELDLTGN 178
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
289-610 |
5.90e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 39.65 E-value: 5.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 289 PLFQLSVLVLRLCSL-----EKIPNFLMYQKNLHVVDLSGNRISGIIPTWL-----LENNPELEVLQLKNNSFTIFQMP- 357
Cdd:cd00116 21 KLLCLQVLRLEGNTLgeeaaKALASALRPQPSLKELCLSLNETGRIPRGLQsllqgLTKGCGLQELDLSDNALGPDGCGv 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 358 ----TSVHNLQVLDFSENNIGGLFPDNFGRVLPNLVHmngsnngfqgnfpssmgemyNISFLDLSYNNLSGElpqsfvsS 433
Cdd:cd00116 101 leslLRSSSLQELKLNNNGLGDRGLRLLAKGLKDLPP--------------------ALEKLVLGRNRLEGA-------S 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 434 CFSLSILqLSHNkfsghflprqtnfTSLIVLRINNNLFTG----KIGVGLLTLVDLCILDMSNNFlegelpplllvfeyl 509
Cdd:cd00116 154 CEALAKA-LRAN-------------RDLKELNLANNGIGDagirALAEGLKANCNLEVLDLNNNG--------------- 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 510 nFLDLSGNLLSGALPShvsldnvlflhnnnftgpipdtfLGSIQILDLRNNKLSGNIPQFVDTQDISF------LLLRGN 583
Cdd:cd00116 205 -LTDEGASALAETLAS-----------------------LKSLEVLNLGDNNLTDAGAAALASALLSPnislltLSLSCN 260
|
330 340 350
....*....|....*....|....*....|.
gi 1063737086 584 SLTGYIPSTLCEF--SKMRL--LDLSDNKLN 610
Cdd:cd00116 261 DITDDGAKDLAEVlaEKESLleLDLRGNKFG 291
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
137-327 |
5.98e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 39.00 E-value: 5.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 137 ELKNLTNLELLDLSGNRIDgSMPvrEFPYLKKLKALDLSSNGIySSMEwqVFCEMKNLQELDLRG--INFVGQLplcfGN 214
Cdd:cd21340 19 NLSLCKNLKVLYLYDNKIT-KIE--NLEFLTNLTHLYLQNNQI-EKIE--NLENLVNLKKLYLGGnrISVVEGL----EN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063737086 215 LNKLRFLDLSSNQLTGNIPPSF------SSLESLEYLSLSDNSFEgffSLNPLTNLTKLKVFIFSSKDdmvqvkiestwq 288
Cdd:cd21340 89 LTNLEELHIENQRLPPGEKLTFdprslaALSNSLRVLNISGNNID---SLEPLAPLRNLEQLDASNNQ------------ 153
|
170 180 190
....*....|....*....|....*....|....*....
gi 1063737086 289 plfqlsvlvlrLCSLEKIPNFLMYQKNLHVVDLSGNRIS 327
Cdd:cd21340 154 -----------ISDLEELLDLLSSWPSLRELDLTGNPVC 181
|
|
|