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Conserved domains on  [gi|1142736541|ref|NP_001335478|]
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transmembrane protein 229B isoform b [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ABC_trans_CmpB super family cl46401
Putative ABC-transporter type IV; CmpB is a family of membrane proteins that are likely to be ...
 50-135 6.05e-04

Putative ABC-transporter type IV; CmpB is a family of membrane proteins that are likely to be part of a two-component type IV ABC-transporter system. Families can transport multiple drugs including ethidium and fluoroquinolones. UniProtKB:Q83XH0 is a member of TCDB family 3.A.1.121.4.


The actual alignment was detected with superfamily member pfam06541:

Pssm-ID: 480741  Cd Length: 149  Bit Score: 38.21  E-value: 6.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1142736541  50 LFIYGTSILIVerMYLRLRGRCPLLLRCLIYTLWTYLWEFTTGFILRQ-FNACPWDYSQFDFDFMGLITLEYAVPWFCGA 128
Cdd:pfam06541  36 CPIYGFGAVLL--LLLLKPLKNNPVLLFLAGAVLATVLEYITGWLLEKlFHARWWDYSDKPFNINGRICLLFSLFWGLLG 113


                  ....*..
gi 1142736541 129 LIMEQFI 135
Cdd:pfam06541 114 VLLVKFI 120
 
Name Accession Description Interval E-value
ABC_trans_CmpB pfam06541
Putative ABC-transporter type IV; CmpB is a family of membrane proteins that are likely to be ...
 50-135 6.05e-04

Putative ABC-transporter type IV; CmpB is a family of membrane proteins that are likely to be part of a two-component type IV ABC-transporter system. Families can transport multiple drugs including ethidium and fluoroquinolones. UniProtKB:Q83XH0 is a member of TCDB family 3.A.1.121.4.


Pssm-ID: 461942  Cd Length: 149  Bit Score: 38.21  E-value: 6.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1142736541  50 LFIYGTSILIVerMYLRLRGRCPLLLRCLIYTLWTYLWEFTTGFILRQ-FNACPWDYSQFDFDFMGLITLEYAVPWFCGA 128
Cdd:pfam06541  36 CPIYGFGAVLL--LLLLKPLKNNPVLLFLAGAVLATVLEYITGWLLEKlFHARWWDYSDKPFNINGRICLLFSLFWGLLG 113


                  ....*..
gi 1142736541 129 LIMEQFI 135
Cdd:pfam06541 114 VLLVKFI 120
 
Name Accession Description Interval E-value
ABC_trans_CmpB pfam06541
Putative ABC-transporter type IV; CmpB is a family of membrane proteins that are likely to be ...
 50-135 6.05e-04

Putative ABC-transporter type IV; CmpB is a family of membrane proteins that are likely to be part of a two-component type IV ABC-transporter system. Families can transport multiple drugs including ethidium and fluoroquinolones. UniProtKB:Q83XH0 is a member of TCDB family 3.A.1.121.4.


Pssm-ID: 461942  Cd Length: 149  Bit Score: 38.21  E-value: 6.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1142736541  50 LFIYGTSILIVerMYLRLRGRCPLLLRCLIYTLWTYLWEFTTGFILRQ-FNACPWDYSQFDFDFMGLITLEYAVPWFCGA 128
Cdd:pfam06541  36 CPIYGFGAVLL--LLLLKPLKNNPVLLFLAGAVLATVLEYITGWLLEKlFHARWWDYSDKPFNINGRICLLFSLFWGLLG 113


                  ....*..
gi 1142736541 129 LIMEQFI 135
Cdd:pfam06541 114 VLLVKFI 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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