|
Name |
Accession |
Description |
Interval |
E-value |
| CID_RPRD2 |
cd17001 |
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 2; ... |
27-145 |
1.51e-83 |
|
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 2; Regulation of nuclear pre-mRNA domain-containing protein 2 (RPRD2) is a CID (CTD-Interacting Domain) domain containing protein that co-purifies with RNA polymerase (Pol) II (RNAP II) and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340798 Cd Length: 125 Bit Score: 268.71 E-value: 1.51e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPE 106
Cdd:cd17001 6 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIVFRESFAEVLPE 85
|
90 100 110
....*....|....*....|....*....|....*....
gi 1560049519 107 AAALVKDPSVSKSIERIFKIWEDRNVYPEDMIVALREAL 145
Cdd:cd17001 86 AAALVKDASVSKSVERIFKIWEERNVYPEETIAALKEAL 124
|
|
| CID |
pfam04818 |
CID domain; This domain binds to the phosphorylated C-terminal domain (CTD) of RNA polymerase ... |
27-138 |
4.14e-42 |
|
CID domain; This domain binds to the phosphorylated C-terminal domain (CTD) of RNA polymerase II. This domain is known as the CTD-interacting domain (CID).
Pssm-ID: 461442 Cd Length: 117 Bit Score: 150.05 E-value: 4.14e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPE 106
Cdd:pfam04818 3 LEKKLSSLNNSQESIQTLSKWILFHRKHAKAIVEVWEKYLKKAKPEKKLHLLYLANDVLQNSRKKGKSEFADAFEPVLPE 82
|
90 100 110
....*....|....*....|....*....|....*
gi 1560049519 107 AAALV---KDPSVSKSIERIFKIWEDRNVYPEDMI 138
Cdd:pfam04818 83 AFASAykkCDEKLKKKLERLLNIWEERNVFSPEVI 117
|
|
| RPR |
smart00582 |
domain present in proteins, which are involved in regulation of nuclear pre-mRNA; |
27-145 |
4.20e-31 |
|
domain present in proteins, which are involved in regulation of nuclear pre-mRNA;
Pssm-ID: 214731 Cd Length: 124 Bit Score: 118.92 E-value: 4.20e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPE 106
Cdd:smart00582 2 FEQKLESLNNSQESIQTLTKWAIEHASHAKEIVELWEKYIKKAPVPRKLPLLYLLDSIVQNSKRKYGSEFGDELGPVFQD 81
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1560049519 107 AAALVKDPSVS---KSIERIFKIWEDRNVYPEDMIVALREAL 145
Cdd:smart00582 82 ALRRVLGAAPEelkKKIRRLLNIWEERGIFPPEVLRPLREKL 123
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
293-619 |
5.23e-08 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 57.62 E-value: 5.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 293 SPVPSPSMDAPSPTgSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDvedmelsdveddgskiivedrkekpvEKPAV 372
Cdd:pfam05109 475 SPTPAGTTSGASPV-TPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATS--------------------------PTPAV 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 373 STGVPTKSTESVSKASPCAPPSVPT-TAAPPLPkplstALLSPSPTLVLPNLANVdlakisSILSSLTSVMKNTGVSSAS 451
Cdd:pfam05109 528 TTPTPNATSPTLGKTSPTSAVTTPTpNATSPTP-----AVTTPTPNATIPTLGKT------SPTSAVTTPTPNATSPTVG 596
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 452 RPSPGIPTSPSNLSSGLKTP----------APATTPSHNPLANILSKVEITPESILSALSKT----QTQSAPALQGLSSL 517
Cdd:pfam05109 597 ETSPQANTTNHTLGGTSSTPvvtsppknatSAVTTGQHNITSSSTSSMSLRPSSISETLSPStsdnSTSHMPLLTSAHPT 676
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 518 LQSVTANPVPASEVTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTSASKASVGQSPVLPSTTF 597
Cdd:pfam05109 677 GGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTGG 756
|
330 340
....*....|....*....|...
gi 1560049519 598 KLPSSSLG-FTGTHNPSPAAPPT 619
Cdd:pfam05109 757 KANSTTGGkHTTGHGARTSTEPT 779
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
288-642 |
2.21e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 2.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 288 PDPEESPVPSPSMDAPSPTGSESPFQGMGGEEPQSPAMESDKSAtPEPVTDNRDVEDMELSDVEDDGSKIiveDRKEKPV 367
Cdd:PHA03247 2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDD-PAPGRVSRPRRARRLGRAAQASSPP---QRPRRRA 2687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 368 EKPAVStgvptkstesvSKASPCAPPSVPTTAAPPlPKPLSTALLSPSPTLVLPNLANVDLAKISSILSSLTSVMKNTGV 447
Cdd:PHA03247 2688 ARPTVG-----------SLTSLADPPPPPPTPEPA-PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPA 2755
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 448 SSASRPSPGIPTSPSNLSSGLKTPAPATTPshnPLANILSkveitpESILSALSKTQTQSAPALQGLSSLLQSVTANPVP 527
Cdd:PHA03247 2756 RPARPPTTAGPPAPAPPAAPAAGPPRRLTR---PAVASLS------ESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 528 ASEVTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTSASKASVGQSPVLPSTTFKLPSSSLGFT 607
Cdd:PHA03247 2827 PLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPE 2906
|
330 340 350
....*....|....*....|....*....|....*
gi 1560049519 608 GTHNPSPAAPPTEVAVCQSSEVSKPKPESESTSPS 642
Cdd:PHA03247 2907 RPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQP 2941
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CID_RPRD2 |
cd17001 |
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 2; ... |
27-145 |
1.51e-83 |
|
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 2; Regulation of nuclear pre-mRNA domain-containing protein 2 (RPRD2) is a CID (CTD-Interacting Domain) domain containing protein that co-purifies with RNA polymerase (Pol) II (RNAP II) and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340798 Cd Length: 125 Bit Score: 268.71 E-value: 1.51e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPE 106
Cdd:cd17001 6 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIVFRESFAEVLPE 85
|
90 100 110
....*....|....*....|....*....|....*....
gi 1560049519 107 AAALVKDPSVSKSIERIFKIWEDRNVYPEDMIVALREAL 145
Cdd:cd17001 86 AAALVKDASVSKSVERIFKIWEERNVYPEETIAALKEAL 124
|
|
| CID_RPRD_like |
cd16981 |
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing proteins; ... |
27-145 |
8.95e-56 |
|
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing proteins; This family is composed of Regulation of nuclear pre-mRNA domain-containing proteins 1A (RPRD1A), 1B (RPRD1B), 2 (RPRD2), yeast Rtt103, and similar proteins. RPRD1A, RPRD1B, and RPRD2 are CID (CTD-Interacting Domain) containing proteins that co-purify with RNA polymerase (Pol) II (RNAP II) and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. Yeast transcription termination factor Rtt103 is a CID containing protein that functions in DNA damage response. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340778 Cd Length: 125 Bit Score: 189.33 E-value: 8.95e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPE 106
Cdd:cd16981 4 LEKKLRSLNNTQQSIQTLSLWCLFHKKHAKQIVKIWLKELKKAKPERKLTLLYLANDVLQNSRRKGAPEFVEAFKKVLPE 83
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1560049519 107 AAALVK---DPSVSKSIERIFKIWEDRNVYPEDMIVALREAL 145
Cdd:cd16981 84 ALALVRsegDESVRKKVLRVLNIWEERNVFGSEFLAELRAIL 125
|
|
| CID |
pfam04818 |
CID domain; This domain binds to the phosphorylated C-terminal domain (CTD) of RNA polymerase ... |
27-138 |
4.14e-42 |
|
CID domain; This domain binds to the phosphorylated C-terminal domain (CTD) of RNA polymerase II. This domain is known as the CTD-interacting domain (CID).
Pssm-ID: 461442 Cd Length: 117 Bit Score: 150.05 E-value: 4.14e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPE 106
Cdd:pfam04818 3 LEKKLSSLNNSQESIQTLSKWILFHRKHAKAIVEVWEKYLKKAKPEKKLHLLYLANDVLQNSRKKGKSEFADAFEPVLPE 82
|
90 100 110
....*....|....*....|....*....|....*
gi 1560049519 107 AAALV---KDPSVSKSIERIFKIWEDRNVYPEDMI 138
Cdd:pfam04818 83 AFASAykkCDEKLKKKLERLLNIWEERNVFSPEVI 117
|
|
| CID_RPRD1 |
cd17002 |
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 1 and ... |
27-147 |
4.10e-37 |
|
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 1 and similar proteins; This subfamily contains Regulation of nuclear pre-mRNA domain-containing proteins 1A (RPRD1A) and 1B (RPRD1B) from jawed vertebrates, CID domain-containing protein 1 (CIDS1 or cids-1) from Caenorhabditis elegans, and similar proteins. RPRD1A and RPRD1B are CID (CTD-Interacting Domain) containing proteins that co-purify with RNA polymerase (Pol) II (RNAP II) and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. RPRD1A and RPRD1B form homodimers and heterodimers through their coiled-coil domains. Both associate directly with RPAP2 phosphatase and serve as CTD scaffolds to coordinate the dephosphorylation of phospho-S5 by RPAP2. The function of CIDS1 is not yet known. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340799 Cd Length: 128 Bit Score: 136.23 E-value: 4.10e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAiIFRESFADVLPE 106
Cdd:cd17002 6 LEKKLAELSNSQQSIQTLSLWLIHHRKHAKTIVRVWLKELRKEKPSKKLTLLYLANDVIQNSRKKGP-EFTKEFAPVLED 84
|
90 100 110 120
....*....|....*....|....*....|....*....|....
gi 1560049519 107 AAALV---KDPSVSKSIERIFKIWEDRNVYPEDMIVALREALTS 147
Cdd:cd17002 85 AFKHVaklTDSEVLKALERILNIWKERQVYEKDFIEQLRAALRK 128
|
|
| RPR |
smart00582 |
domain present in proteins, which are involved in regulation of nuclear pre-mRNA; |
27-145 |
4.20e-31 |
|
domain present in proteins, which are involved in regulation of nuclear pre-mRNA;
Pssm-ID: 214731 Cd Length: 124 Bit Score: 118.92 E-value: 4.20e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPE 106
Cdd:smart00582 2 FEQKLESLNNSQESIQTLTKWAIEHASHAKEIVELWEKYIKKAPVPRKLPLLYLLDSIVQNSKRKYGSEFGDELGPVFQD 81
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1560049519 107 AAALVKDPSVS---KSIERIFKIWEDRNVYPEDMIVALREAL 145
Cdd:smart00582 82 ALRRVLGAAPEelkKKIRRLLNIWEERGIFPPEVLRPLREKL 123
|
|
| CID_Rtt103 |
cd17003 |
CID (CTD-Interacting Domain) of yeast transcription termination factor Rtt103 and similar ... |
30-145 |
1.98e-26 |
|
CID (CTD-Interacting Domain) of yeast transcription termination factor Rtt103 and similar proteins; Yeast transcription termination factor Rtt103 is a CID (CTD-Interacting Domain) containing protein that functions in DNA damage response. It associates with sites of DNA breaks and is essential for recovery from DNA double strand breaks in the chromosome. CID binds tightly to the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II (RNAP II). Rtt103 CID preferentially interacts with CTD phosphorylated at Ser2. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340800 Cd Length: 127 Bit Score: 105.77 E-value: 1.98e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 30 KFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTY--PHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEA 107
Cdd:cd17003 7 KLNALNETQESIVSISQWVLFHYRHADEIAEIWSDYLLKSSVnsRRKLLLIYLANDVVQQAKAKKKTEFIDAFSKVLPEV 86
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 1560049519 108 AALVK---DPSVSKSIERIFKIWEDRNVYPEDMIVALREAL 145
Cdd:cd17003 87 LEKIYpslPSDIKKKIKRVVNVWKQRQIFSKDVIDDIEERL 127
|
|
| CID_RPRD1A |
cd17011 |
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 1A; ... |
27-145 |
1.23e-25 |
|
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 1A; Regulation of nuclear pre-mRNA domain-containing protein 1A (RPRD1A) is also called Cyclin-dependent kinase inhibitor 2B-related protein or p15INK4B-related protein (P15RS). RPRD1A is a CID (CTD-Interacting Domain) containing protein that co-purifies with RNA polymerase (Pol) II (RNAP II) and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. RPRD1A form homodimers and heterodimers with RPRD1B through their coiled-coil domains. Both RPRD1A and RPRD1B associate directly with RPAP2 phosphatase and serve as CTD scaffolds to coordinate the dephosphorylation of phospho-S5 by RPAP2. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340808 Cd Length: 128 Bit Score: 103.58 E-value: 1.23e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAiIFRESFADVLPE 106
Cdd:cd17011 6 LEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGP-EFTKDFAPVIVE 84
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 1560049519 107 AAALVK---DPSVSKSIERIFKIWEDRNVYPEDMIVALREAL 145
Cdd:cd17011 85 AFKHVSsetDESCKKHLGRVLSIWEERSVYENDVLEQLKQAL 126
|
|
| CID_RPRD1B |
cd17012 |
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 1B; ... |
27-142 |
2.43e-24 |
|
CID (CTD-Interacting Domain) of Regulation of nuclear pre-mRNA domain-containing protein 1B; Regulation of nuclear pre-mRNA domain-containing protein 1B (RPRD1B) is also called Cell cycle-related and expression-elevated protein in tumor (CREPT). RPRD1B is a CID (CTD-Interacting Domain) containing protein that co-purifies with RNA polymerase (Pol) II (RNAP II) and three other RNAP II-associated proteins, RPAP2, GRINL1A and RECQL5, but not with the Mediator complex. CID binds tightly to the carboxy-terminal domain (CTD) of RNAP II. During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. RPRD1B form homodimers and heterodimers with RPRD1A through their coiled-coil domains. Both RPRD1A and RPRD1B associate directly with RPAP2 phosphatase and serve as CTD scaffolds to coordinate the dephosphorylation of phospho-S5 by RPAP2. RPRD1B is highly expressed during tumorigenesis and in endometrial cancer, has been shown to promote tumor growth by accelerating the cell cycle. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340809 Cd Length: 129 Bit Score: 99.69 E-value: 2.43e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 27 LDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAIIFREsFADVLPE 106
Cdd:cd17012 7 LEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSSRKLTFLYLANDVIQNSKRKGPEFTRE-FESVLVD 85
|
90 100 110
....*....|....*....|....*....|....*....
gi 1560049519 107 AAALVK---DPSVSKSIERIFKIWEDRNVYPEDMIVALR 142
Cdd:cd17012 86 AFSHVAreaDEGCKKPLERLLNIWQERSVYGGDFIQQLK 124
|
|
| CID |
cd03562 |
CID (CTD-Interacting Domain) family; The CTD-Interacting Domain (CID) is present in several ... |
36-144 |
3.00e-14 |
|
CID (CTD-Interacting Domain) family; The CTD-Interacting Domain (CID) is present in several eukaryotic RNA-processing factors including yeast proteins, Pcf11 and Nrd1, and vertebrate proteins, CTD-associated factors 8 (SCAF8) and Regulation of nuclear pre-mRNA domain-containing proteins (such as RPRD1 and RPRD2). Pcf11 is a conserved and essential subunit of the yeast cleavage factor IA, which is required for polyadenylation-dependent 3'-RNA processing and transcription termination. Nrd1 is implicated in polyadenylation-independent 3'-RNA processing. CID binds tightly to the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II (RNAP II). During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340766 Cd Length: 123 Bit Score: 70.62 E-value: 3.00e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 36 NTMESIQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAiIFRESFADVLPEA---AALVK 112
Cdd:cd03562 13 LSQQSITTLTKWAIHHIKHSRPIVTVIEREIRKCKPNRKLTFLYLIDSIIRNSKRKGP-EFTKDFSPVIVELfkhVYSET 91
|
90 100 110
....*....|....*....|....*....|..
gi 1560049519 113 DPSVSKSIERIFKIWEDRNVYPEDMIVALREA 144
Cdd:cd03562 92 DEDCKKKLGRVLSIWEERNVFENSVLEQLKQA 123
|
|
| CID_SCAF8_like |
cd16983 |
CID (CTD-Interacting Domain) of SR-related and CTD-associated factor 8 and similar proteins; ... |
41-144 |
4.01e-08 |
|
CID (CTD-Interacting Domain) of SR-related and CTD-associated factor 8 and similar proteins; This subfamily includes SR-related and CTD-associated factors 8 (SCAF8) and 4 (SCAF4), and similar proteins. SCAF4 is also called Splicing factor arginine serine rich 15 (SFRS15). Members may play roles in mRNA processing. Both SCAF4 and SCAF8 contains a CTD-interacting domain (CID) at the amino terminus and a Ser/Arg-rich domain followed by an RNA recognition motif. CID binds tightly to the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II (RNAP II). During transcription, RNAP II synthesizes eukaryotic messenger RNA. Transcription is coupled to RNA processing through the CTD, which consists of up to 52 repeats of the sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. CID contains eight alpha-helices in a right-handed superhelical arrangement, which closely resembles that of the VHS domains and ARM (Armadillo) repeat proteins, except for its two amino-terminal helices.
Pssm-ID: 340780 Cd Length: 131 Bit Score: 53.38 E-value: 4.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 41 IQGLSSWCIENKKHHSTIVYHWMKWLRRSTYPHRLNLFYLANDVIQNCKRKNAII---FRESFADVL-PEAAALVKDPSV 116
Cdd:cd16983 22 INAITKLAIKAIKFYKHVVQSVEKFIQKCKPEYKLPGLYVIDSIIRQSRHQYGKEkdvYAPRFAKNLsKTFLNLLKCPEK 101
|
90 100
....*....|....*....|....*....
gi 1560049519 117 SKS-IERIFKIWEDRNVYPEDMIVALREA 144
Cdd:cd16983 102 DKPkVKRVLNLWQKNGVFPKEIIQPLLDA 130
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
293-619 |
5.23e-08 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 57.62 E-value: 5.23e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 293 SPVPSPSMDAPSPTgSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDvedmelsdveddgskiivedrkekpvEKPAV 372
Cdd:pfam05109 475 SPTPAGTTSGASPV-TPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATS--------------------------PTPAV 527
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 373 STGVPTKSTESVSKASPCAPPSVPT-TAAPPLPkplstALLSPSPTLVLPNLANVdlakisSILSSLTSVMKNTGVSSAS 451
Cdd:pfam05109 528 TTPTPNATSPTLGKTSPTSAVTTPTpNATSPTP-----AVTTPTPNATIPTLGKT------SPTSAVTTPTPNATSPTVG 596
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 452 RPSPGIPTSPSNLSSGLKTP----------APATTPSHNPLANILSKVEITPESILSALSKT----QTQSAPALQGLSSL 517
Cdd:pfam05109 597 ETSPQANTTNHTLGGTSSTPvvtsppknatSAVTTGQHNITSSSTSSMSLRPSSISETLSPStsdnSTSHMPLLTSAHPT 676
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 518 LQSVTANPVPASEVTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTSASKASVGQSPVLPSTTF 597
Cdd:pfam05109 677 GGENITQVTPASTSTHHVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTPPKNATSPQAPSGQKTAVPTVTSTGG 756
|
330 340
....*....|....*....|...
gi 1560049519 598 KLPSSSLG-FTGTHNPSPAAPPT 619
Cdd:pfam05109 757 KANSTTGGkHTTGHGARTSTEPT 779
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
288-642 |
2.21e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.63 E-value: 2.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 288 PDPEESPVPSPSMDAPSPTGSESPFQGMGGEEPQSPAMESDKSAtPEPVTDNRDVEDMELSDVEDDGSKIiveDRKEKPV 367
Cdd:PHA03247 2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDD-PAPGRVSRPRRARRLGRAAQASSPP---QRPRRRA 2687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 368 EKPAVStgvptkstesvSKASPCAPPSVPTTAAPPlPKPLSTALLSPSPTLVLPNLANVDLAKISSILSSLTSVMKNTGV 447
Cdd:PHA03247 2688 ARPTVG-----------SLTSLADPPPPPPTPEPA-PHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPA 2755
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 448 SSASRPSPGIPTSPSNLSSGLKTPAPATTPshnPLANILSkveitpESILSALSKTQTQSAPALQGLSSLLQSVTANPVP 527
Cdd:PHA03247 2756 RPARPPTTAGPPAPAPPAAPAAGPPRRLTR---PAVASLS------ESRESLPSPWDPADPPAAVLAPAAALPPAASPAG 2826
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 528 ASEVTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTSASKASVGQSPVLPSTTFKLPSSSLGFT 607
Cdd:PHA03247 2827 PLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPE 2906
|
330 340 350
....*....|....*....|....*....|....*
gi 1560049519 608 GTHNPSPAAPPTEVAVCQSSEVSKPKPESESTSPS 642
Cdd:PHA03247 2907 RPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQP 2941
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
288-551 |
1.82e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.55 E-value: 1.82e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 288 PDPEESPVPSPSMDAP-SPTGSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDVEDMELSDVEDDGSKiivedrkeKP 366
Cdd:PHA03247 2733 PALPAAPAPPAVPAGPaTPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPW--------DP 2804
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 367 VEKPAVSTGVPTKSTESVSKASPCAPPSVPTTAAPPLPKPLSTALLSPSPTLVlpnlANVDLAKISSILSSLTSVMKNTG 446
Cdd:PHA03247 2805 ADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVA----PGGDVRRRPPSRSPAAKPAAPAR 2880
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 447 VSSASRPSPGIPTSPSNLSSGLKTPAPATTPSHNPLANILSKVEITPesilsalsktQTQSAPALQGLSSLLQSVTANPV 526
Cdd:PHA03247 2881 PPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPP----------QPQPPPPPPPRPQPPLAPTTDPA 2950
|
250 260
....*....|....*....|....*
gi 1560049519 527 PASEvtsqSTTASPASTTGSAVKGR 551
Cdd:PHA03247 2951 GAGE----PSGAVPQPWLGALVPGR 2971
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
370-689 |
1.32e-04 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 46.45 E-value: 1.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 370 PAVSTGVPTKSTESVSKASPCAPPSVPTTAAPPLPKPLST----ALLSPSPTlvlpNLANVDLAKISSILSSLTSVmkNT 445
Cdd:pfam05109 442 PNTTTGLPSSTHVPTNLTAPASTGPTVSTADVTSPTPAGTtsgaSPVTPSPS----PRDNGTESKAPDMTSPTSAV--TT 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 446 GVSSASRPSPGIPTSPSNLSS---GLKTPAPA-TTPSHNPLANILSKVEITPESILSALSKTQTQSA---PALQGLSSLL 518
Cdd:pfam05109 516 PTPNATSPTPAVTTPTPNATSptlGKTSPTSAvTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTSAvttPTPNATSPTV 595
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 519 -----QSVTANPVPASEVTSQSTTASPASTTGSAVKGRNLLSSTQSfipkSFNYSPSSSTSEVSSTSASKASVGQSPVL- 592
Cdd:pfam05109 596 getspQANTTNHTLGGTSSTPVVTSPPKNATSAVTTGQHNITSSST----SSMSLRPSSISETLSPSTSDNSTSHMPLLt 671
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 593 ---PSTTFKLPSSSLGFTGTHNPSPAAPPTEVAVcqSSEVSKPKPESESTSPSLEmkihNFLKGNP--------GFSGLN 661
Cdd:pfam05109 672 sahPTGGENITQVTPASTSTHHVSTSSPAPRPGT--TSQASGPGNSSTSTKPGEV----NVTKGTPpknatspqAPSGQK 745
|
330 340 350
....*....|....*....|....*....|....*
gi 1560049519 662 LNIPILSSLGSSAPS-------EGHASDFQRGPTS 689
Cdd:pfam05109 746 TAVPTVTSTGGKANSttggkhtTGHGARTSTEPTT 780
|
|
| PRK11901 |
PRK11901 |
hypothetical protein; Reviewed |
373-553 |
3.09e-04 |
|
hypothetical protein; Reviewed
Pssm-ID: 237015 [Multi-domain] Cd Length: 327 Bit Score: 44.67 E-value: 3.09e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 373 STGVPTKSTESVSKASPCAPPSVPTTAAPPL-PKPLSTALLSPSPTLVLPNLAN-----VDLAKISSILSSLTSVMKNTG 446
Cdd:PRK11901 84 SSSLSSGNQSSPSAANNTSDGHDASGVKNTApPQDISAPPISPTPTQAAPPQTPngqqrIELPGNISDALSQQQGQVNAA 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 447 VSSASRPSPGIPTSPSNLSSGLKTPAPATTPSHN--PLANILSKVEITPESILSALSKTQTQSAP-ALQGLSSLLQSvta 523
Cdd:PRK11901 164 SQNAQGNTSTLPTAPATVAPSKGAKVPATAETHPtpPQKPATKKPAVNHHKTATVAVPPATSGKPkSGAASARALSS--- 240
|
170 180 190
....*....|....*....|....*....|
gi 1560049519 524 npVPASEVTSQSTTASPASTTGSAVKGRNL 553
Cdd:PRK11901 241 --APASHYTLQLSSASRSDTLNAYAKKQNL 268
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
288-551 |
9.30e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.01 E-value: 9.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 288 PDPEESPVPSPSMDAP-SPTGSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKP 366
Cdd:PHA03307 82 NESRSTPTWSLSTLAPaSPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAA 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 367 VEKPAVSTG-------VPTKSTESVSKASPCAPPSVPTTAAPPLPKPLST--ALLSPSPTLVLPNLANVDLAKISSILSS 437
Cdd:PHA03307 162 VASDAASSRqaalplsSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSpiSASASSPAPAPGRSAADDAGASSSDSSS 241
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 438 LTSVMKN-------------------------TGVSSASRPSPGIPTSPSNLSSGLKTPAPATTPSHNPLANILSKVEIT 492
Cdd:PHA03307 242 SESSGCGwgpenecplprpapitlptriweasGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSS 321
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1560049519 493 PESILSALSKTQTQSAPALQGLSSLLQSVTAN----PVPASEVTSQSTTASPASTTGSAVKGR 551
Cdd:PHA03307 322 RESSSSSTSSSSESSRGAAVSPGPSPSRSPSPsrppPPADPSSPRKRPRPSRAPSSPAASAGR 384
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
281-416 |
1.37e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 1.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 281 DQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDVEDMELSDVEDDGSKIIVE 360
Cdd:PHA03307 793 EAAFRRPGRLRRSGPAADAASRTASKRKSRSHTPDGGSESSGPARPPGAAARPPPARSSESSKSKPAAAGGRARGKNGRR 872
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 1560049519 361 DrkekpvekpavSTGVPTKSTESVSKASPCAPPSVPTTAAPPLPKPLSTALLSPSP 416
Cdd:PHA03307 873 R-----------PRPPEPRARPGAAAPPKAAAAAPPAGAPAPRPRPAPRVKLGPMP 917
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
379-644 |
1.42e-03 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 43.02 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 379 KSTESVSKASPCAPPSVPTTAAPPLP---KPLSTALLSPSPTLVLPNLANVDLAKISSILSSLTSVMKNTGVSSAsrPSP 455
Cdd:pfam17823 128 QSLPAAIAALPSEAFSAPRAAACRANasaAPRAAIAAASAPHAASPAPRTAASSTTAASSTTAASSAPTTAASSA--PAT 205
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 456 GIPTSPSNLSS-GLKTPAPATT----PSHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTANPVPASE 530
Cdd:pfam17823 206 LTPARGISTAAtATGHPAAGTAlaavGNSSPAAGTVTAAVGTVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKH 285
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 531 VTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTSASKASVGQSPVLPSTT---FKLPSSSlgft 607
Cdd:pfam17823 286 MPSDTMARNPAAPMGAQAQGPIIQVSTDQPVHNTAGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTkaqAKEPSAS---- 361
|
250 260 270
....*....|....*....|....*....|....*..
gi 1560049519 608 gthnPSPaAPPTEVAvcqssevskpkPESESTSPSLE 644
Cdd:pfam17823 362 ----PVP-VLHTSMI-----------PEVEATSPTTQ 382
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
285-478 |
1.95e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.85 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 285 STLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKE 364
Cdd:PHA03307 177 SSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECP 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 365 KPVEKPAVSTGVPTKSTESVSKASPCAPPSVPTTAAPPLPKPLSTALLSPSPTLVLPNLANV------DLAKISSILSSL 438
Cdd:PHA03307 257 LPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSsssresSSSSTSSSSESS 336
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 1560049519 439 TSVMKNTGVSSASRPSPGIPTSPSNLSSGLKTPAPATTPS 478
Cdd:PHA03307 337 RGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPS 376
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
288-639 |
2.91e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 2.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 288 PDPEESPVPSPsmDAPSPTGSESP--FQGMGGEEPQSPAM----------ESDKSATPEP--------VTDNRDVEDmel 347
Cdd:PHA03247 2496 PDPGGGGPPDP--DAPPAPSRLAPaiLPDEPVGEPVHPRMltwirgleelASDDAGDPPPplppaappAAPDRSVPP--- 2570
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 348 SDVEDDGSKIIVEDRKEKPVEKPAVSTGVPTKSTESVSKASPCAPPSVPTTAAPPLPKPLSTALLSPSP---TLVLPNLA 424
Cdd:PHA03247 2571 PRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDphpPPTVPPPE 2650
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 425 NVDLAKISSILSSLTSVMKNTGVSSASRPS-----PGIPTSPSNLSSGLKTPAPATTPSHNPLAnilskveITPESILSA 499
Cdd:PHA03247 2651 RPRDDPAPGRVSRPRRARRLGRAAQASSPPqrprrRAARPTVGSLTSLADPPPPPPTPEPAPHA-------LVSATPLPP 2723
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 500 LSKTQTQSAPALQGLSSLLQSVTANPVPASE--VTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVS 577
Cdd:PHA03247 2724 GPAAARQASPALPAAPAPPAVPAGPATPGGParPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWD 2803
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1560049519 578 STSASKASVGQSPVLPSTTfkLPSsslgftgthnpSPAAPPTEVAVCQSSEVSKPKPESEST 639
Cdd:PHA03247 2804 PADPPAAVLAPAAALPPAA--SPA-----------GPLPPPTSAQPTAPPPPPGPPPPSLPL 2852
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
286-643 |
3.81e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 42.08 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 286 TLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEEPQSPAMESDKSATPEPVTDNRDvedmelSDVEDDGSKIIVEDRKEK 365
Cdd:PHA03307 69 TGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPA------SPPPSPAPDLSEMLRPVG 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 366 PVEKPAVSTGVPTksteSVSKASPCAPPSVPTTAAPPLPKPLSTALLSPSPTLVLPNLANvdlakissilssltsvmknt 445
Cdd:PHA03307 143 SPGPPPAASPPAA----GASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTP-------------------- 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 446 gvSSASRPSPGIPTSPSNLSSGLKTPAPATTP-SHNPLANILSKVEITPESILSALSKTQTQSAPALQGLSSLLQSVTAN 524
Cdd:PHA03307 199 --PAAASPRPPRRSSPISASASSPAPAPGRSAaDDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWN 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1560049519 525 PvPASEVTSQSTTASPASTTGSAVKGRNLLSSTQSFIPKSFNYSPSSSTSEVSSTSASKASVGQSPVLPSTTFKLPSSSL 604
Cdd:PHA03307 277 G-PSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSR 355
|
330 340 350
....*....|....*....|....*....|....*....
gi 1560049519 605 GFTGTHNPSPAAPPTEVAVCQSSEVSKPKPESESTSPSL 643
Cdd:PHA03307 356 PPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAV 394
|
|
| |
