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Conserved domains on  [gi|1572048692|ref|NP_001355522|]
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Protein TAPT1 homolog [Caenorhabditis elegans]

Protein Classification

TAPT1 family protein( domain architecture ID 10526511)

TAPT1 family protein is a DUF747 domain-containing protein; similar to vertebrate transmembrane anterior posterior transformation protein 1 that may be involved in patterning of the vertebrate axial skeleton

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF747 pfam05346
Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. ...
 1-182 3.69e-85

Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. It was previously annotated as including a putative receptor for human cytomegalovirus gH but this has has since been disputed. Analysis of the mouse Tapt1 protein (transmembrane anterior posterior transformation 1) has shown it to be involved in patterning of the vertebrate axial skeleton.


:

Pssm-ID: 398815  Cd Length: 311  Bit Score: 260.52  E-value: 3.69e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1572048692   1 MMSNNFVELKGSVFKKFAKANLFQMACSDVRERFHIFALLFVVMIRNMTAVNWNIDSFTEMIPDIIMVVGCEYFVDWLKH 80
Cdd:pfam05346 121 LLSNQFVEIKSSVFKKFEKENLFQITCADVVERFQLFLFLLIIALRNLVEVSSSNDWFGTLLGPLLLVLGSEVLVDWLKH 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1572048692  81 AFITKFNEINAEVYKDFTITIAFDVIRSRDQSAFSDYSDQVSRRMGFIPIPLSIMIIRVLSQTFTLDNWGSC-------- 152
Cdd:pfam05346 201 AFITKFNNIRPSVYRRFLDVLCKDYLSSRQKNAFVDQSHKVTRRLGFPPLPLACLFIRMLPQTYHMLLSTSLplislltg 280

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1572048692 153 -IIFGIGWLLVFAVKICNGVVMLGQACHHVK 182
Cdd:pfam05346 281 lLLFLLVFLILLLLKLLLGILLLGYARRRYK 311
 
Name Accession Description Interval E-value
DUF747 pfam05346
Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. ...
 1-182 3.69e-85

Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. It was previously annotated as including a putative receptor for human cytomegalovirus gH but this has has since been disputed. Analysis of the mouse Tapt1 protein (transmembrane anterior posterior transformation 1) has shown it to be involved in patterning of the vertebrate axial skeleton.


Pssm-ID: 398815  Cd Length: 311  Bit Score: 260.52  E-value: 3.69e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1572048692   1 MMSNNFVELKGSVFKKFAKANLFQMACSDVRERFHIFALLFVVMIRNMTAVNWNIDSFTEMIPDIIMVVGCEYFVDWLKH 80
Cdd:pfam05346 121 LLSNQFVEIKSSVFKKFEKENLFQITCADVVERFQLFLFLLIIALRNLVEVSSSNDWFGTLLGPLLLVLGSEVLVDWLKH 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1572048692  81 AFITKFNEINAEVYKDFTITIAFDVIRSRDQSAFSDYSDQVSRRMGFIPIPLSIMIIRVLSQTFTLDNWGSC-------- 152
Cdd:pfam05346 201 AFITKFNNIRPSVYRRFLDVLCKDYLSSRQKNAFVDQSHKVTRRLGFPPLPLACLFIRMLPQTYHMLLSTSLplislltg 280

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1572048692 153 -IIFGIGWLLVFAVKICNGVVMLGQACHHVK 182
Cdd:pfam05346 281 lLLFLLVFLILLLLKLLLGILLLGYARRRYK 311
 
Name Accession Description Interval E-value
DUF747 pfam05346
Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. ...
 1-182 3.69e-85

Eukaryotic membrane protein family; This family is a family of eukaryotic membrane proteins. It was previously annotated as including a putative receptor for human cytomegalovirus gH but this has has since been disputed. Analysis of the mouse Tapt1 protein (transmembrane anterior posterior transformation 1) has shown it to be involved in patterning of the vertebrate axial skeleton.


Pssm-ID: 398815  Cd Length: 311  Bit Score: 260.52  E-value: 3.69e-85
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1572048692   1 MMSNNFVELKGSVFKKFAKANLFQMACSDVRERFHIFALLFVVMIRNMTAVNWNIDSFTEMIPDIIMVVGCEYFVDWLKH 80
Cdd:pfam05346 121 LLSNQFVEIKSSVFKKFEKENLFQITCADVVERFQLFLFLLIIALRNLVEVSSSNDWFGTLLGPLLLVLGSEVLVDWLKH 200

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1572048692  81 AFITKFNEINAEVYKDFTITIAFDVIRSRDQSAFSDYSDQVSRRMGFIPIPLSIMIIRVLSQTFTLDNWGSC-------- 152
Cdd:pfam05346 201 AFITKFNNIRPSVYRRFLDVLCKDYLSSRQKNAFVDQSHKVTRRLGFPPLPLACLFIRMLPQTYHMLLSTSLplislltg 280

                         170       180       190
                  ....*....|....*....|....*....|.
gi 1572048692 153 -IIFGIGWLLVFAVKICNGVVMLGQACHHVK 182
Cdd:pfam05346 281 lLLFLLVFLILLLLKLLLGILLLGYARRRYK 311
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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