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Conserved domains on  [gi|1972299388|ref|NP_001380243|]
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SANT domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SWIRM-assoc_1 pfam16495
SWIRM-associated region 1; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 ...
 189-264 8.40e-31

SWIRM-associated region 1; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 proteins is of low-complexity and or disordered. However, there are several short regions that are quite highly conserved. This is one of these regions. The function of the individual regions is not known.


:

Pssm-ID: 465142 [Multi-domain]  Cd Length: 84  Bit Score: 114.54  E-value: 8.40e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972299388 189 VKAKHLAQIEERRIKSLVAQLVETQMKKLEMKLRHFDELEQIMDKERESLEYQRHQLILERQAFHMDQLKYLENRA 264
Cdd:pfam16495   9 AKAKVLASQEEREIQRLVALLVETQLKKLELKLKQFEELEKLLERERRQLERQRQQLFLERLAFKKQRLEVAEKLA 84
RSC8 super family cl34960
RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / ...
 1-239 8.39e-25

RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription];


The actual alignment was detected with superfamily member COG5259:

Pssm-ID: 227584 [Multi-domain]  Cd Length: 531  Bit Score: 107.66  E-value: 8.39e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972299388   1 MFKDDWNKVCDHVGTRTQHECVLKFLQLPIQDPYLTENlsSDKAEAAPGGaakevlgplafqpVPFSQSGNPVMSTVAFL 80
Cdd:COG5259   296 MYGDDWDKVARHVGTKTKEQCILHFLQLPIEDNYLSKG--DGKGDNSKGR-------------LPFDGSENPVLSTISFL 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972299388  81 ASVVDPQVaaaatkaameefgklkeeipplvaeaheknvaamaektgqvdgavgltksglkpAEEAAGDSDEKMDTntnd 160
Cdd:COG5259   361 AGIVNPRV------------------------------------------------------QSEKQRAIIKSGKI---- 382

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1972299388 161 dVPSTTEAKSAIDKGVQAAAASCLAaaavKAKHLAQIEERRIKSLVAQLVETQMKKLEMKLRHFDELEQIMDKERESLE 239
Cdd:COG5259   383 -SHINRESQEHIEEVIEYALDSGKE----KAKLQATNEERKMERLRNVLIQAQLEKLKMKLGHLKELEKSTSLERQELD 456
SWIRM-assoc_3 pfam16498
SWIRM-associated domain at the C-terminal; Much of the higher eukaryote SWI/SNF complex ...
 84-149 9.26e-20

SWIRM-associated domain at the C-terminal; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 proteins is of low-complexity and or disordered. However, there are several short regions that are quite highly conserved. This is one of these regions. The function of the individual regions is not known.


:

Pssm-ID: 465145 [Multi-domain]  Cd Length: 67  Bit Score: 83.17  E-value: 9.26e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972299388  84 VDPQVAAAATKAAMEEFGKLKEEIPPLVAEAHEKNVAAMAEKTGQVDGAVGLTKSGLKPAEEAAGD 149
Cdd:pfam16498   1 VDPRVAAAAAKAAMEEFSKIKEEVPPALVEAHVKNVEEAAKKGGKVDPAFGLEKSGIAGTDPEEPE 66
 
Name Accession Description Interval E-value
SWIRM-assoc_1 pfam16495
SWIRM-associated region 1; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 ...
 189-264 8.40e-31

SWIRM-associated region 1; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 proteins is of low-complexity and or disordered. However, there are several short regions that are quite highly conserved. This is one of these regions. The function of the individual regions is not known.


Pssm-ID: 465142 [Multi-domain]  Cd Length: 84  Bit Score: 114.54  E-value: 8.40e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972299388 189 VKAKHLAQIEERRIKSLVAQLVETQMKKLEMKLRHFDELEQIMDKERESLEYQRHQLILERQAFHMDQLKYLENRA 264
Cdd:pfam16495   9 AKAKVLASQEEREIQRLVALLVETQLKKLELKLKQFEELEKLLERERRQLERQRQQLFLERLAFKKQRLEVAEKLA 84
RSC8 COG5259
RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / ...
 1-239 8.39e-25

RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227584 [Multi-domain]  Cd Length: 531  Bit Score: 107.66  E-value: 8.39e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972299388   1 MFKDDWNKVCDHVGTRTQHECVLKFLQLPIQDPYLTENlsSDKAEAAPGGaakevlgplafqpVPFSQSGNPVMSTVAFL 80
Cdd:COG5259   296 MYGDDWDKVARHVGTKTKEQCILHFLQLPIEDNYLSKG--DGKGDNSKGR-------------LPFDGSENPVLSTISFL 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972299388  81 ASVVDPQVaaaatkaameefgklkeeipplvaeaheknvaamaektgqvdgavgltksglkpAEEAAGDSDEKMDTntnd 160
Cdd:COG5259   361 AGIVNPRV------------------------------------------------------QSEKQRAIIKSGKI---- 382

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1972299388 161 dVPSTTEAKSAIDKGVQAAAASCLAaaavKAKHLAQIEERRIKSLVAQLVETQMKKLEMKLRHFDELEQIMDKERESLE 239
Cdd:COG5259   383 -SHINRESQEHIEEVIEYALDSGKE----KAKLQATNEERKMERLRNVLIQAQLEKLKMKLGHLKELEKSTSLERQELD 456
SWIRM-assoc_3 pfam16498
SWIRM-associated domain at the C-terminal; Much of the higher eukaryote SWI/SNF complex ...
 84-149 9.26e-20

SWIRM-associated domain at the C-terminal; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 proteins is of low-complexity and or disordered. However, there are several short regions that are quite highly conserved. This is one of these regions. The function of the individual regions is not known.


Pssm-ID: 465145 [Multi-domain]  Cd Length: 67  Bit Score: 83.17  E-value: 9.26e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972299388  84 VDPQVAAAATKAAMEEFGKLKEEIPPLVAEAHEKNVAAMAEKTGQVDGAVGLTKSGLKPAEEAAGD 149
Cdd:pfam16498   1 VDPRVAAAAAKAAMEEFSKIKEEVPPALVEAHVKNVEEAAKKGGKVDPAFGLEKSGIAGTDPEEPE 66
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 1-28 4.30e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 35.17  E-value: 4.30e-03
                          10        20
                  ....*....|....*....|....*...
gi 1972299388   1 MFKDDWNKVCDHVGTRTQHECVLKFLQL 28
Cdd:pfam00249  18 KLGNRWKKIAKLLPGRTDNQCKNRWQNY 45
 
Name Accession Description Interval E-value
SWIRM-assoc_1 pfam16495
SWIRM-associated region 1; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 ...
 189-264 8.40e-31

SWIRM-associated region 1; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 proteins is of low-complexity and or disordered. However, there are several short regions that are quite highly conserved. This is one of these regions. The function of the individual regions is not known.


Pssm-ID: 465142 [Multi-domain]  Cd Length: 84  Bit Score: 114.54  E-value: 8.40e-31
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972299388 189 VKAKHLAQIEERRIKSLVAQLVETQMKKLEMKLRHFDELEQIMDKERESLEYQRHQLILERQAFHMDQLKYLENRA 264
Cdd:pfam16495   9 AKAKVLASQEEREIQRLVALLVETQLKKLELKLKQFEELEKLLERERRQLERQRQQLFLERLAFKKQRLEVAEKLA 84
RSC8 COG5259
RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / ...
 1-239 8.39e-25

RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227584 [Multi-domain]  Cd Length: 531  Bit Score: 107.66  E-value: 8.39e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972299388   1 MFKDDWNKVCDHVGTRTQHECVLKFLQLPIQDPYLTENlsSDKAEAAPGGaakevlgplafqpVPFSQSGNPVMSTVAFL 80
Cdd:COG5259   296 MYGDDWDKVARHVGTKTKEQCILHFLQLPIEDNYLSKG--DGKGDNSKGR-------------LPFDGSENPVLSTISFL 360

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1972299388  81 ASVVDPQVaaaatkaameefgklkeeipplvaeaheknvaamaektgqvdgavgltksglkpAEEAAGDSDEKMDTntnd 160
Cdd:COG5259   361 AGIVNPRV------------------------------------------------------QSEKQRAIIKSGKI---- 382

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1972299388 161 dVPSTTEAKSAIDKGVQAAAASCLAaaavKAKHLAQIEERRIKSLVAQLVETQMKKLEMKLRHFDELEQIMDKERESLE 239
Cdd:COG5259   383 -SHINRESQEHIEEVIEYALDSGKE----KAKLQATNEERKMERLRNVLIQAQLEKLKMKLGHLKELEKSTSLERQELD 456
SWIRM-assoc_3 pfam16498
SWIRM-associated domain at the C-terminal; Much of the higher eukaryote SWI/SNF complex ...
 84-149 9.26e-20

SWIRM-associated domain at the C-terminal; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 proteins is of low-complexity and or disordered. However, there are several short regions that are quite highly conserved. This is one of these regions. The function of the individual regions is not known.


Pssm-ID: 465145 [Multi-domain]  Cd Length: 67  Bit Score: 83.17  E-value: 9.26e-20
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1972299388  84 VDPQVAAAATKAAMEEFGKLKEEIPPLVAEAHEKNVAAMAEKTGQVDGAVGLTKSGLKPAEEAAGD 149
Cdd:pfam16498   1 VDPRVAAAAAKAAMEEFSKIKEEVPPALVEAHVKNVEEAAKKGGKVDPAFGLEKSGIAGTDPEEPE 66
Myb_DNA-binding pfam00249
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ...
 1-28 4.30e-03

Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.


Pssm-ID: 459731 [Multi-domain]  Cd Length: 46  Bit Score: 35.17  E-value: 4.30e-03
                          10        20
                  ....*....|....*....|....*...
gi 1972299388   1 MFKDDWNKVCDHVGTRTQHECVLKFLQL 28
Cdd:pfam00249  18 KLGNRWKKIAKLLPGRTDNQCKNRWQNY 45
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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