TRPM8 channel-associated factor 1 [Rattus norvegicus]
Protein Classification
M60 family metallopeptidase( domain architecture ID 13879573)
M60 family metallopeptidase similar to enhancin, a peptidase from granulosis viruses that affects Lepidoptera, and increases the potency of viral infection
List of domain hits
| Name | Accession | Description | Interval | E-value | |||||
| Peptidase_M60 | pfam13402 | Peptidase M60, enhancin and enhancin-like; This family of peptidases contains a zinc ... |
633-890 | 1.88e-99 | |||||
Peptidase M60, enhancin and enhancin-like; This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonization of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family. : Pssm-ID: 433178 [Multi-domain] Cd Length: 268 Bit Score: 311.62 E-value: 1.88e-99
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| M60-like_N | pfam17291 | N-terminal domain of M60-like peptidases; This accessory domain has a jelly roll topology. |
522-631 | 5.73e-32 | |||||
N-terminal domain of M60-like peptidases; This accessory domain has a jelly roll topology. : Pssm-ID: 435844 [Multi-domain] Cd Length: 106 Bit Score: 120.13 E-value: 5.73e-32
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| Name | Accession | Description | Interval | E-value | |||||
| Peptidase_M60 | pfam13402 | Peptidase M60, enhancin and enhancin-like; This family of peptidases contains a zinc ... |
633-890 | 1.88e-99 | |||||
Peptidase M60, enhancin and enhancin-like; This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonization of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family. Pssm-ID: 433178 [Multi-domain] Cd Length: 268 Bit Score: 311.62 E-value: 1.88e-99
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| M60-like_N | pfam17291 | N-terminal domain of M60-like peptidases; This accessory domain has a jelly roll topology. |
522-631 | 5.73e-32 | |||||
N-terminal domain of M60-like peptidases; This accessory domain has a jelly roll topology. Pssm-ID: 435844 [Multi-domain] Cd Length: 106 Bit Score: 120.13 E-value: 5.73e-32
|
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| Name | Accession | Description | Interval | E-value | |||||
| Peptidase_M60 | pfam13402 | Peptidase M60, enhancin and enhancin-like; This family of peptidases contains a zinc ... |
633-890 | 1.88e-99 | |||||
Peptidase M60, enhancin and enhancin-like; This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonization of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family. Pssm-ID: 433178 [Multi-domain] Cd Length: 268 Bit Score: 311.62 E-value: 1.88e-99
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| M60-like_N | pfam17291 | N-terminal domain of M60-like peptidases; This accessory domain has a jelly roll topology. |
522-631 | 5.73e-32 | |||||
N-terminal domain of M60-like peptidases; This accessory domain has a jelly roll topology. Pssm-ID: 435844 [Multi-domain] Cd Length: 106 Bit Score: 120.13 E-value: 5.73e-32
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| Blast search parameters | ||||
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