|
Name |
Accession |
Description |
Interval |
E-value |
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
48-343 |
3.78e-129 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 370.76 E-value: 3.78e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 48 TLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWVPDGNGTS 127
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 128 LYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPGdSMTPVSLLADpSFVRAWIGGVGDCKLGGNYGPTVAVQREAQK 207
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYFKG-GEKGVSALVS-SFRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 208 RGCEQVLWLYGPDHQLTEVGTMNIFVYWtheDGvlELVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRA 287
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK---DG--ELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELYEA 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2301398554 288 LeegrvrEVFGSGTACQVCPVHQILYEGKQlhiPTMENGPELILRFQKELKAIQYG 343
Cdd:cd01557 233 D------EVFATGTAAVVTPVGEIDYRGKE---PGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
1-353 |
2.36e-126 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 366.40 E-value: 2.36e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 1 MTKEPQKKPAPSQaLLFGKTFTDHMLMVEWNNKAgWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFR 80
Cdd:PRK13357 9 PTSDEKRAIDWAN-LGFGYVFTDHMVVIDYKDGK-WHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLFR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 81 PWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWV-PDGNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVG 159
Cdd:PRK13357 87 PDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVpPYGEGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPVG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 160 SYFPGDsMTPVSLLADPSFVRAWIGGVGDCKLGGNYGPTVAVQREAQKRGCEQVLWLYGPDHQ-LTEVGTMNIF-VYwth 237
Cdd:PRK13357 167 AYFKGG-VKPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFFfIT--- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 238 EDGVlelVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRALEEGRVREVFGSGTACQVCPVHQILYEGKQ 317
Cdd:PRK13357 243 KDGT---VTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGIKYKDKE 318
|
330 340 350
....*....|....*....|....*....|....*...
gi 2301398554 318 LHIPTMENGPeLILRFQKELKAIQYGASA--HDWMFRV 353
Cdd:PRK13357 319 FVIGDGEVGP-VTQKLYDELTGIQFGDVEdpHGWIVKV 355
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
36-353 |
2.39e-100 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 298.98 E-value: 2.39e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 36 WGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEV 115
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 116 DKDWVPD-GNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPGDSmTPVSLLADPSFVRAWIGGVGDCKLGGN 194
Cdd:TIGR01123 81 NKDWVPPyGSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKGGL-APVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 195 YGPTVAVQREAQKRGCEQVLWLYGPDHQ-LTEVGTMNIFVYWTheDGvlELVTPPLNGVILPGVVRQSLLDLARTWGeFR 273
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLDPVEHTyIEEVGAMNFFFITG--DG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 274 VAERKVTMKELKRALEEGrvREVFGSGTACQVCPVHQILYEGKQLHIPTMENGpELILRFQKELKAIQYG--ASAHDWMF 351
Cdd:TIGR01123 235 VEERRIDIDELKAFVEAG--EIVFACGTAAVITPVGEIQHGGKEVVFASGQPG-EVTKALYDELTDIQYGdfEDPYGWIV 311
|
..
gi 2301398554 352 RV 353
Cdd:TIGR01123 312 EV 313
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
36-346 |
4.70e-72 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 225.45 E-value: 4.70e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 36 WGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGgdqqvRLFRPWLNMDRMLRSARRLCLP-DFDKQELLECIRQLIE 114
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPiPYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 115 VDKDwvpdgngTSLYVRPVLIGNEPSLGVGMVT-QALLYVILCPVGSYFPGDSMTPVSLLADPsFVRAWIGGVGDCKlGG 193
Cdd:COG0115 79 ANGL-------EDGYIRPQVTRGVGGRGVFAEEyEPTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 194 NYGPTVAVQREAQKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDLARTWGeFR 273
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLL-DTDGYVAEGSGSNVFIV---KDGVL--VTPPLSGGILPGITRDSVIELARELG-IP 222
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2301398554 274 VAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQIlyEGKQlhIPTMENGPeLILRFQKELKAIQYGASA 346
Cdd:COG0115 223 VEERPISLEELYTA------DEVFLTGTAAEVTPVTEI--DGRP--IGDGKPGP-VTRRLRELYTDIVRGEAE 284
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
61-311 |
5.84e-35 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 127.47 E-value: 5.84e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 61 QLFEGLKAYKGgdqqvRLFRPWLNMDRMLRSARRLCLP-DFDKQELLECIRQLIEVDKDWVPdgngtslYVRPVLIGNEP 139
Cdd:pfam01063 1 GVFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVG-------RLRLTVSRGPG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 140 SLGV-GMVTQALLYVILCPVGSYFPGDSMTPVSLLADPSFVRAwiggvgDCKlGGNYGPTVAVQREAQKRGCEQVLwLYG 218
Cdd:pfam01063 69 GFGLpTSDPTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 219 PDHQLTEVGTMNIFvyWTHEDgvlELVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRAleegrvREVFG 298
Cdd:pfam01063 141 EDGNVTEGSTSNVF--LVKGG---TLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFL 208
|
250
....*....|...
gi 2301398554 299 SGTACQVCPVHQI 311
Cdd:pfam01063 209 TNSLRGVTPVSSI 221
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| BCAT_beta_family |
cd01557 |
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the ... |
48-343 |
3.78e-129 |
|
BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and alpha-ketoisovalerate. The enzyme requires pyridoxal 5'-phosphate (PLP) as a cofactor to catalyze the reaction. It has been found that mammals have two foms of the enzyme - mitochondrial and cytosolic forms while bacteria contain only one form of the enzyme. The mitochondrial form plays a significant role in skeletal muscle glutamine and alanine synthesis and in interorgan nitrogen metabolism.Members of this subgroup are widely distributed in all three forms of life.
Pssm-ID: 238798 Cd Length: 279 Bit Score: 370.76 E-value: 3.78e-129
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 48 TLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWVPDGNGTS 127
Cdd:cd01557 1 SLHPATHALHYGQAVFEGLKAYRTPDGKIVLFRPDENAERLNRSARRLGLPPFSVEEFIDAIKELVKLDADWVPYGGGAS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 128 LYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPGdSMTPVSLLADpSFVRAWIGGVGDCKLGGNYGPTVAVQREAQK 207
Cdd:cd01557 81 LYIRPFIFGTDPQLGVSPALEYLFAVFASPVGAYFKG-GEKGVSALVS-SFRRAAPGGPGAAKAGGNYAASLLAQKEAAE 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 208 RGCEQVLWLYGPDHQLTEVGTMNIFVYWtheDGvlELVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRA 287
Cdd:cd01557 159 KGYDQALWLDGAHGYVAEVGTMNIFFVK---DG--ELITPPLDGSILPGITRDSILELARDLG-IKVEERPITRDELYEA 232
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 2301398554 288 LeegrvrEVFGSGTACQVCPVHQILYEGKQlhiPTMENGPELILRFQKELKAIQYG 343
Cdd:cd01557 233 D------EVFATGTAAVVTPVGEIDYRGKE---PGEGEVGPVTKKLYDLLTDIQYG 279
|
|
| PRK13357 |
PRK13357 |
branched-chain amino acid aminotransferase; Provisional |
1-353 |
2.36e-126 |
|
branched-chain amino acid aminotransferase; Provisional
Pssm-ID: 237363 Cd Length: 356 Bit Score: 366.40 E-value: 2.36e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 1 MTKEPQKKPAPSQaLLFGKTFTDHMLMVEWNNKAgWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFR 80
Cdd:PRK13357 9 PTSDEKRAIDWAN-LGFGYVFTDHMVVIDYKDGK-WHDARLVPYGPLELDPAATVLHYGQEIFEGLKAYRHKDGSIVLFR 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 81 PWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEVDKDWV-PDGNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVG 159
Cdd:PRK13357 87 PDANAKRLQRSADRLLMPELPEELFLEAVKQLVKADRDWVpPYGEGASLYLRPFMIATEPFLGVKPAEEYIFCVIASPVG 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 160 SYFPGDsMTPVSLLADPSFVRAWIGGVGDCKLGGNYGPTVAVQREAQKRGCEQVLWLYGPDHQ-LTEVGTMNIF-VYwth 237
Cdd:PRK13357 167 AYFKGG-VKPVSIWVSDEYDRAAPGGTGAAKVGGNYAASLLAQAEAKEKGCDQVLYLDAVEHTyIEEVGGMNFFfIT--- 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 238 EDGVlelVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRALEEGRVREVFGSGTACQVCPVHQILYEGKQ 317
Cdd:PRK13357 243 KDGT---VTPPLSGSILPGITRDSLLQLAEDLG-LTVEERPVSIDEWQADAASGEFTEAFACGTAAVITPIGGIKYKDKE 318
|
330 340 350
....*....|....*....|....*....|....*...
gi 2301398554 318 LHIPTMENGPeLILRFQKELKAIQYGASA--HDWMFRV 353
Cdd:PRK13357 319 FVIGDGEVGP-VTQKLYDELTGIQFGDVEdpHGWIVKV 355
|
|
| ilvE_II |
TIGR01123 |
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are ... |
36-353 |
2.39e-100 |
|
branched-chain amino acid aminotransferase, group II; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family less similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 233278 Cd Length: 313 Bit Score: 298.98 E-value: 2.39e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 36 WGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARRLCLPDFDKQELLECIRQLIEV 115
Cdd:TIGR01123 1 WHNGRLTPYGPLHLDPGSTVLHYGQECFEGLKAYRCADGSIVLFRPDANAARLRRSARRLLMPELPDELFLEALRQLVKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 116 DKDWVPD-GNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPGDSmTPVSLLADPSFVRAWIGGVGDCKLGGN 194
Cdd:TIGR01123 81 NKDWVPPyGSGASLYLRPFVIGTEPNLGVRPAPEYLFYVFASPVGAYFKGGL-APVSIFVTTEYDRAAPGGTGAVKVGGN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 195 YGPTVAVQREAQKRGCEQVLWLYGPDHQ-LTEVGTMNIFVYWTheDGvlELVTPPLNGVILPGVVRQSLLDLARTWGeFR 273
Cdd:TIGR01123 160 YAASLLAQAKAAEQGCDQVVYLDPVEHTyIEEVGAMNFFFITG--DG--ELVTPPLSGSILPGITRDSLLQLAKDLG-ME 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 274 VAERKVTMKELKRALEEGrvREVFGSGTACQVCPVHQILYEGKQLHIPTMENGpELILRFQKELKAIQYG--ASAHDWMF 351
Cdd:TIGR01123 235 VEERRIDIDELKAFVEAG--EIVFACGTAAVITPVGEIQHGGKEVVFASGQPG-EVTKALYDELTDIQYGdfEDPYGWIV 311
|
..
gi 2301398554 352 RV 353
Cdd:TIGR01123 312 EV 313
|
|
| PLPDE_IV |
cd00449 |
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, ... |
54-337 |
1.65e-80 |
|
PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and 4-amino-4-deoxychorismate lyases (ADCL). BCAT catalyzes the reversible transamination reaction between the L-branched-chain amino and alpha-keto acids. DAAT catalyzes the synthesis of D-glutamic acid and D-alanine, and ADCL converts 4-amino-4-deoxychorismate to p-aminobenzoate and pyruvate. Except for a few enzymes, i. e., Escherichia coli and Salmonella BCATs, which are homohexamers arranged as a double trimer, the class IV PLPDEs are homodimers. Homodimer formation is required for catalytic activity.
Pssm-ID: 238254 [Multi-domain] Cd Length: 256 Bit Score: 245.97 E-value: 1.65e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 54 SGLHYSLQLFEGLKAYKGgdqqvRLFRPWLNMDRMLRSARRLCLP-DFDKQELLECIRQLIEVdkdwvpdGNGTSLYVRP 132
Cdd:cd00449 2 RGLHYGDGVFEGLRAGKG-----RLFRLDEHLDRLNRSAKRLGLPiPYDREELREALKELVAA-------NNGASLYIRP 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 133 VLIGNEPSLGVGM--VTQALLYVILCPVGSYFPGdSMTPVSLLADPSFVRAWIGGVGDCKLGGNYgPTVAVQREAQKRGC 210
Cdd:cd00449 70 LLTRGVGGLGVAPppSPEPTFVVFASPVGAYAKG-GEKGVRLITSPDRRRAAPGGTGDAKTGGNL-NSVLAKQEAAEAGA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 211 EQVLWLYGpDHQLTEVGTMNIFVYWtheDGvlELVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRAlee 290
Cdd:cd00449 148 DEALLLDD-NGYVTEGSASNVFIVK---DG--ELVTPPLDGGILPGITRDSVIELAKELG-IKVEERPISLDELYAA--- 217
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 2301398554 291 grvREVFGSGTACQVCPVHQILYEGKqlhipTMENGPELILRFQKEL 337
Cdd:cd00449 218 ---DEVFLTGTAAEVTPVTEIDGRGI-----GDGKPGPVTRKLRELL 256
|
|
| IlvE |
COG0115 |
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid ... |
36-346 |
4.70e-72 |
|
Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439885 [Multi-domain] Cd Length: 285 Bit Score: 225.45 E-value: 4.70e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 36 WGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGgdqqvRLFRPWLNMDRMLRSARRLCLP-DFDKQELLECIRQLIE 114
Cdd:COG0115 4 WLNGELVPEEEATISVLDRGLHYGDGVFEGIRAYDG-----RLFRLDEHLARLNRSAKRLGIPiPYTEEELLEAIRELVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 115 VDKDwvpdgngTSLYVRPVLIGNEPSLGVGMVT-QALLYVILCPVGSYFPGDSMTPVSLLADPsFVRAWIGGVGDCKlGG 193
Cdd:COG0115 79 ANGL-------EDGYIRPQVTRGVGGRGVFAEEyEPTVIIIASPLPAYPAEAYEKGVRVITSP-YRRAAPGGLGGIK-TG 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 194 NYGPTVAVQREAQKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDLARTWGeFR 273
Cdd:COG0115 150 NYLNNVLAKQEAKEAGADEALLL-DTDGYVAEGSGSNVFIV---KDGVL--VTPPLSGGILPGITRDSVIELARELG-IP 222
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2301398554 274 VAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQIlyEGKQlhIPTMENGPeLILRFQKELKAIQYGASA 346
Cdd:COG0115 223 VEERPISLEELYTA------DEVFLTGTAAEVTPVTEI--DGRP--IGDGKPGP-VTRRLRELYTDIVRGEAE 284
|
|
| PLN02782 |
PLN02782 |
Branched-chain amino acid aminotransferase |
17-318 |
1.36e-60 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 215418 Cd Length: 403 Bit Score: 199.69 E-value: 1.36e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 17 FGKTFTDHMLMVEWNNKAGWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARRLC 96
Cdd:PLN02782 77 FGLVPTDYMYIMKCNRDGEFSKGELQRFGNIELSPSAGVLNYGQGLFEGLKAYRKEDGNILLFRPEENAIRMRNGAERMC 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 97 LPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPgDSMTPVSLLADP 176
Cdd:PLN02782 157 MPAPTVEQFVEAVKETVLANKRWVPPPGKGSLYIRPLLMGSGAVLGLAPAPEYTFLIYVSPVGNYFK-EGVAPINLIVEN 235
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 177 SFVRAWIGGVGDCKLGGNYGPTVAVQREAQKRGCEQVLWLygpD--HQ--LTEVGTMNIFVYwthEDGVLElvTPPLNGV 252
Cdd:PLN02782 236 EFHRATPGGTGGVKTIGNYAAVLKAQSIAKAKGYSDVLYL---DcvHKkyLEEVSSCNIFIV---KDNVIS--TPAIKGT 307
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2301398554 253 ILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQILYEGKQL 318
Cdd:PLN02782 308 ILPGITRKSIIDVARSQG-FQVEERNVTVDELLEA------DEVFCTGTAVVVSPVGSITYKGKRV 366
|
|
| PLN03117 |
PLN03117 |
Branched-chain-amino-acid aminotransferase; Provisional |
15-353 |
1.61e-53 |
|
Branched-chain-amino-acid aminotransferase; Provisional
Pssm-ID: 178664 Cd Length: 355 Bit Score: 180.13 E-value: 1.61e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 15 LLFGKTFTDHMLMVEWNNKAGWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARR 94
Cdd:PLN03117 25 LGFALVPTDYMYVAKCKQGESFSEGKIVPYGDISISPCAGILNYGQGLFEGLKAYRTEDGRITLFRPDQNALRMQTGADR 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 95 LCLPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPGDSmtPVSLLA 174
Cdd:PLN03117 105 LCMTPPSLEQFVEAVKQTVLANKKWVPPPGKGTLYIRPLLIGSGAVLGVAPAPEYTFLIYASPVGNYHKASS--GLNLKV 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 175 DPSFVRAWIGGVGDCKLGGNYGPTVAVQREAQKRGCEQVLWL-YGPDHQLTEVGTMNIFVYwthEDGVLElvTPPLNGVI 253
Cdd:PLN03117 183 DHKHRRAHSGGTGGVKSCTNYSPVVKSLIEAKSSGFSDVLFLdAATGKNIEELSACNIFIL---KGNIVS--TPPTSGTI 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 254 LPGVVRQSLLDLARTWGeFRVAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQILYEGKQLHIPTMENGpeLILRF 333
Cdd:PLN03117 258 LPGVTRKSISELARDIG-YQVEERDVSVDELLEA------EEVFCTGTAVVVKAVETVTFHDKKVKYRTGEEA--LSTKL 328
|
330 340
....*....|....*....|..
gi 2301398554 334 QKELKAIQYGA--SAHDWMFRV 353
Cdd:PLN03117 329 HLILTNIQMGVveDKKGWMVEI 350
|
|
| PLN02883 |
PLN02883 |
Branched-chain amino acid aminotransferase |
15-353 |
6.81e-49 |
|
Branched-chain amino acid aminotransferase
Pssm-ID: 178471 Cd Length: 384 Bit Score: 168.74 E-value: 6.81e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 15 LLFGKTFTDHMLMVEWNNKAGWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARR 94
Cdd:PLN02883 57 LGFSLVRTDFMFATKSCRDGNFEQGYLSRYGNIELNPAAGILNYGQGLIEGMKAYRGEDGRILLFRPELNAMRMKIGAER 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 95 LCLPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPgDSMTPVSLLA 174
Cdd:PLN02883 137 MCMHSPSVHQFIEGVKQTVLANRRWVPPPGKGSLYLRPLLFGSGASLGVAAAPEYTFLVFGSPVQNYFK-EGTAALNLYV 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 175 DPSFVRAWIGGVGDCKLGGNYGPTVAVQREAQKRGCEQVLWLYG-PDHQLTEVGTMNIFVYWTHedgvlELVTPPLNGVI 253
Cdd:PLN02883 216 EEVIPRAYLGGTGGVKAISNYGPVLEVMRRAKSRGFSDVLYLDAdTGKNIEEVSAANIFLVKGN-----IIVTPATSGTI 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 254 LPGVVRQSLLDLARTWGeFRVAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQILYEGKQLHIPTMENGPELILRf 333
Cdd:PLN02883 291 LGGITRKSIIEIALDLG-YKVEERRVPVEELKEA------EEVFCTGTAAGVASVGSITFKNTRTEYKVGDGIVTQQLR- 362
|
330 340
....*....|....*....|..
gi 2301398554 334 qKELKAIQYGA--SAHDWMFRV 353
Cdd:PLN02883 363 -SILLGIQTGSiqDTKDWVLQI 383
|
|
| PLN02259 |
PLN02259 |
branched-chain-amino-acid aminotransferase 2 |
15-343 |
7.78e-47 |
|
branched-chain-amino-acid aminotransferase 2
Pssm-ID: 177901 Cd Length: 388 Bit Score: 163.35 E-value: 7.78e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 15 LLFGKTFTDHMLMVEWNNKAGWGPPRIQPFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVRLFRPWLNMDRMLRSARR 94
Cdd:PLN02259 61 LGFGLNPADYMYVMKCSKDGEFTQGELSPYGNIQLSPSAGVLNYGQAIYEGTKAYRKENGKLLLFRPDHNAIRMKLGAER 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 95 LCLPDFDKQELLECIRQLIEVDKDWVPDGNGTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGSYFPgDSMTPVSLLA 174
Cdd:PLN02259 141 MLMPSPSVDQFVNAVKQTALANKRWVPPAGKGTLYIRPLLMGSGPILGLGPAPEYTFIVYASPVGNYFK-EGMAALNLYV 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 175 DPSFVRAWIGGVGDCKLGGNYGPTVAVQREAQKRGCEQVLWLYGPDHQ-LTEVGTMNIFVYWTHedgvlELVTPPLNGVI 253
Cdd:PLN02259 220 EEEYVRAAPGGAGGVKSITNYAPVLKALSRAKSRGFSDVLYLDSVKKKyLEEASSCNVFVVKGR-----TISTPATNGTI 294
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 254 LPGVVRQSLLDLARTWGeFRVAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQILYEGKQLHIPTMENgpELILRF 333
Cdd:PLN02259 295 LEGITRKSVMEIASDQG-YQVVEKAVHVDEVMDA------DEVFCTGTAVVVAPVGTITYQEKRVEYKTGDE--SVCQKL 365
|
330
....*....|
gi 2301398554 334 QKELKAIQYG 343
Cdd:PLN02259 366 RSVLVGIQTG 375
|
|
| Aminotran_4 |
pfam01063 |
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to ... |
61-311 |
5.84e-35 |
|
Amino-transferase class IV; The D-amino acid transferases (D-AAT) are required by bacteria to catalyze the synthesis of D-glutamic acid and D-alanine, which are essential constituents of bacterial cell wall and are the building block for other D-amino acids. Despite the difference in the structure of the substrates, D-AATs and L-ATTs have strong similarity.
Pssm-ID: 395844 [Multi-domain] Cd Length: 221 Bit Score: 127.47 E-value: 5.84e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 61 QLFEGLKAYKGgdqqvRLFRPWLNMDRMLRSARRLCLP-DFDKQELLECIRQLIEVDKDWVPdgngtslYVRPVLIGNEP 139
Cdd:pfam01063 1 GVFETLRVYNG-----KIFFLDEHLARLRRSAKLLGIPlPFDEEDLRKIIEELLKANGLGVG-------RLRLTVSRGPG 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 140 SLGV-GMVTQALLYVILCPVGSYFPGDSMTPVSLLADPSFVRAwiggvgDCKlGGNYGPTVAVQREAQKRGCEQVLwLYG 218
Cdd:pfam01063 69 GFGLpTSDPTLAIFVSALPPPPESKKKGVISSLVRRNPPSPLP------GAK-TLNYLENVLARREAKAQGADDAL-LLD 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 219 PDHQLTEVGTMNIFvyWTHEDgvlELVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRAleegrvREVFG 298
Cdd:pfam01063 141 EDGNVTEGSTSNVF--LVKGG---TLYTPPLESGILPGITRQALLDLAKALG-LEVEERPITLADLQEA------DEAFL 208
|
250
....*....|...
gi 2301398554 299 SGTACQVCPVHQI 311
Cdd:pfam01063 209 TNSLRGVTPVSSI 221
|
|
| PRK06606 |
PRK06606 |
branched-chain amino acid transaminase; |
43-311 |
5.00e-25 |
|
branched-chain amino acid transaminase;
Pssm-ID: 235841 Cd Length: 306 Bit Score: 102.92 E-value: 5.00e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 43 PFQNLTLHPACSGLHYSLQLFEGLKAYKGGDQQVrLFRPWLNMDRMLRSARRLCLP-DFDKQELLECIRQLIEVdkdwvp 121
Cdd:PRK06606 17 PWEDAKVHVLTHALHYGTGVFEGIRAYDTPKGPA-IFRLREHTKRLFNSAKILRMEiPYSVDELMEAQREVVRK------ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 122 dgNG-TSLYVRP-VLIGNEpSLGV---GMVTQALLYVIlcPVGSYFPGDSMTP-----VS---LLADPSF-VRAwiggvg 187
Cdd:PRK06606 90 --NNlKSAYIRPlVFVGDE-GLGVrphGLPTDVAIAAW--PWGAYLGEEALEKgirvkVSswtRHAPNSIpTRA------ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 188 dcKLGGNYGPTVAVQREAQKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGVleLVTPPLNGVILPGVVRQSLLDLAR 267
Cdd:PRK06606 159 --KASGNYLNSILAKTEARRNGYDEALLL-DVEGYVSEGSGENIFIV---RDGV--LYTPPLTSSILEGITRDTVITLAK 230
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 2301398554 268 TWGeFRVAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQI 311
Cdd:PRK06606 231 DLG-IEVIERRITRDELYIA------DEVFFTGTAAEVTPIREV 267
|
|
| ilvE_I |
TIGR01122 |
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are ... |
43-311 |
3.50e-24 |
|
branched-chain amino acid aminotransferase, group I; Among the class IV aminotransferases are two phylogenetically separable groups of branched-chain amino acid aminotransferase (IlvE). The last common ancestor of the two lineages appears also to have given rise to a family of D-amino acid aminotransferases (DAAT). This model represents the IlvE family more strongly similar to the DAAT family. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 130192 Cd Length: 298 Bit Score: 100.51 E-value: 3.50e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 43 PFQNLTLHPACSGLHYSLQLFEGLKAYKgGDQQVRLFRPWLNMDRMLRSARRLCLP-DFDKQELLECIRQLIEVDkdwvp 121
Cdd:TIGR01122 8 DWEDAKVHVLTHALHYGTGVFEGIRAYD-TDKGPAIFRLKEHIQRLYDSAKIYRMEiPYSKEELMEATRETLRKN----- 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 122 dgNGTSLYVRPVLIGNEPSLGVGMVTQAL--LYVILCPVGSYFpGDSMTPVSLLAD-PSFVRAWIGGV-GDCKLGGNYGP 197
Cdd:TIGR01122 82 --NLRSAYIRPLVFRGDGDLGLNPRAGYKpdVIIAAWPWGAYL-GEEALEKGIDAKvSSWRRNAPNTIpTAAKAGGNYLN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 198 TVAVQREAQKRGCEQVLWLyGPDHQLTEVGTMNIFVYwthEDGVleLVTPPLNGVILPGVVRQSLLDLARTWGeFRVAER 277
Cdd:TIGR01122 159 SLLAKSEARRHGYDEAILL-DVEGYVAEGSGENIFIV---KDGV--LFTPPVTSSILPGITRDTVITLAKELG-IEVVEQ 231
|
250 260 270
....*....|....*....|....*....|....
gi 2301398554 278 KVTMKELKRAleegrvREVFGSGTACQVCPVHQI 311
Cdd:TIGR01122 232 PISREELYTA------DEAFFTGTAAEITPIREV 259
|
|
| D-AAT_like |
cd01558 |
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes ... |
54-311 |
1.22e-23 |
|
D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and D-glutamate in addition to other D-amino acids. The enzyme like other members of this superfamily requires PLP as a cofactor. Members of this subgroup are found in all three forms of life.
Pssm-ID: 238799 [Multi-domain] Cd Length: 270 Bit Score: 98.44 E-value: 1.22e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 54 SGLHYSLQLFEGLKAYKGgdqqvRLFRPWLNMDRMLRSARRLCLPD-FDKQELLECIRQLIEvdKDWVPDGNGtslYVRP 132
Cdd:cd01558 19 RGFLFGDGVYEVIRVYNG-----KPFALDEHLDRLYRSAKELRIDIpYTREELKELIRELVA--KNEGGEGDV---YIQV 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 133 vlignepSLGVGMV-------TQALLYVILCPVGSYFPGDSMTPVSLLADPsfVRAWiggvGDCKL-GGNYGPTVAVQRE 204
Cdd:cd01558 89 -------TRGVGPRghdfpkcVKPTVVIITQPLPLPPAELLEKGVRVITVP--DIRW----LRCDIkSLNLLNNVLAKQE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 205 AQKRGCEQVlWLYGPDHQLTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKEL 284
Cdd:cd01558 156 AKEAGADEA-ILLDADGLVTEGSSSNVFIV---KNGVL--VTPPLDNGILPGITRATVIELAKELG-IPVEERPFSLEEL 228
|
250 260
....*....|....*....|....*..
gi 2301398554 285 KRAleegrvREVFGSGTACQVCPVHQI 311
Cdd:cd01558 229 YTA------DEVFLTSTTAEVMPVVEI 249
|
|
| ADCL_like |
cd01559 |
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent ... |
55-311 |
8.22e-18 |
|
ADCL_like: 4-Amino-4-deoxychorismate lyase: is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate. Based on the information available from the crystal structure, most members of this subgroup are likely to function as dimers. The enzyme from E.Coli, the structure of which is available, is a homodimer that is folded into a small and a larger domain. The coenzyme pyridoxal 5; -phosphate resides at the interface of the two domains that is linked by a flexible loop. Members of this subgroup are found in Eukaryotes and bacteria.
Pssm-ID: 238800 [Multi-domain] Cd Length: 249 Bit Score: 81.59 E-value: 8.22e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 55 GLHYSLQLFEGLKAYKGgdqQVRLFRPWLnmDRMLRSARRLCLPDFDKQELLECIRQLIEVDKdwVPDGngtslYVRPVL 134
Cdd:cd01559 3 GFAYGDGVFETMRALDG---RLFLLDAHL--ARLERSARRLGIPEPDLPRLRAALESLLAAND--IDEG-----RIRLIL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 135 ignepSLGVGmvtqALLYVIL-CPVGSYFPGDSMTPVSLLADPsfVRAWIGGVGDCKLGG-------NYGPTVAVQREAQ 206
Cdd:cd01559 71 -----SRGPG----GRGYAPSvCPGPALYVSVIPLPPAWRQDG--VRLITCPVRLGEQPLlaglkhlNYLENVLAKREAR 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 207 KRGCEQVLWLYGPDHqLTEVGTMNIFvyWTHeDGvlELVTPPLNGVILPGVVRQSLLDLARTWGEfRVAERKVTMKELKR 286
Cdd:cd01559 140 DRGADEALFLDTDGR-VIEGTASNLF--FVK-DG--ELVTPSLDRGGLAGITRQRVIELAAAKGY-AVDERPLRLEDLLA 212
|
250 260
....*....|....*....|....*
gi 2301398554 287 AleegrvREVFGSGTACQVCPVHQI 311
Cdd:cd01559 213 A------DEAFLTNSLLGVAPVTAI 231
|
|
| PRK08320 |
PRK08320 |
branched-chain amino acid aminotransferase; Reviewed |
55-311 |
2.57e-11 |
|
branched-chain amino acid aminotransferase; Reviewed
Pssm-ID: 236238 [Multi-domain] Cd Length: 288 Bit Score: 63.35 E-value: 2.57e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 55 GLHYSLQLFEGLKAYKGgdqqvRLFRPWLNMDRMLRSARRLCL-PDFDKQELLECIRQLIEVDkdwvpdgNGTSLYVRPV 133
Cdd:PRK08320 25 GFLYGDGVFEGIRAYNG-----RVFRLKEHIDRLYDSAKAIMLeIPLSKEEMTEIVLETLRKN-------NLRDAYIRLV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 134 LignepSLGVGMV-------TQALLYVILCPVGSYfPGDsMTPVSLLADPSFVRAWIGGVGDCKLGG-NYGPTVAVQREA 205
Cdd:PRK08320 93 V-----SRGVGDLgldprkcPKPTVVCIAEPIGLY-PGE-LYEKGLKVITVSTRRNRPDALSPQVKSlNYLNNILAKIEA 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 206 QKRGCEQVLWLygpDHQ--LTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKE 283
Cdd:PRK08320 166 NLAGVDEAIML---NDEgyVAEGTGDNIFIV---KNGKL--ITPPTYAGALEGITRNAVIEIAKELG-IPVREELFTLHD 236
|
250 260
....*....|....*....|....*...
gi 2301398554 284 LKRAleegrvREVFGSGTACQVCPVHQI 311
Cdd:PRK08320 237 LYTA------DEVFLTGTAAEVIPVVKV 258
|
|
| PRK07544 |
PRK07544 |
branched-chain amino acid aminotransferase; Validated |
43-311 |
5.05e-11 |
|
branched-chain amino acid aminotransferase; Validated
Pssm-ID: 181025 Cd Length: 292 Bit Score: 62.69 E-value: 5.05e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 43 PFQNLTLHPACSGLHYSLQLFEGLKAYKGgdqqvRLFRPWLNMDRMLRSARRLclpDFD----KQELLECIRQLIEVdkd 118
Cdd:PRK07544 19 PWRDAKVHVLTHGLHYASSVFEGERAYGG-----KIFKLREHSERLRRSAELL---DFEipysVAEIDAAKKETLAA--- 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 119 wvpdgNG-TSLYVRPVLIGNEPSLGVGMVTQALLYVILC-PVGSYF-PGDSMTPVSL-LA-----DPSF--VRAwiggvg 187
Cdd:PRK07544 88 -----NGlTDAYVRPVAWRGSEMMGVSAQQNKIHLAIAAwEWPSYFdPEAKMKGIRLdIAkwrrpDPETapSAA------ 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 188 dcKLGGNYGPTVAVQREAQKRGCEQVLWLygpDH--QLTEVGTMNIFVYwthEDGVLELVTPplnGVILPGVVRQSLLDL 265
Cdd:PRK07544 157 --KAAGLYMICTISKHAAEAKGYADALML---DYrgYVAEATGANIFFV---KDGVIHTPTP---DCFLDGITRQTVIEL 225
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 2301398554 266 ARTWGeFRVAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQI 311
Cdd:PRK07544 226 AKRRG-IEVVERHIMPEELAGF------SECFLTGTAAEVTPVSEI 264
|
|
| PRK07849 |
PRK07849 |
aminodeoxychorismate lyase; |
63-287 |
1.93e-09 |
|
aminodeoxychorismate lyase;
Pssm-ID: 236114 [Multi-domain] Cd Length: 292 Bit Score: 58.05 E-value: 1.93e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 63 FEGLKAYKGgdqQVRLFRPWLnmDRMLRSARRLCLPDFDKQELLECIRQLIEvdkDWvpDGNGTSLYVRPVLignepSLG 142
Cdd:PRK07849 42 FETLLVRDG---RPCNLEAHL--ERLARSAALLDLPEPDLDRWRRAVELAIE---EW--RAPEDEAALRLVY-----SRG 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 143 VGMVTQALLYVILCPVGSYFPGDSMTPVSLL-------ADPSfVRA-WIggvgdckLGG----NYGPTVAVQREAQKRGC 210
Cdd:PRK07849 107 RESGGAPTAWVTVSPVPERVARARREGVSVItldrgypSDAA-ERApWL-------LAGaktlSYAVNMAALRYAARRGA 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 211 EQVlwlygpdhqltevgtmnIFvywTHEDG-VLE-------------LVTPPLNGVILPGVVRQSLLDLARTWGeFRVAE 276
Cdd:PRK07849 179 DDV-----------------IF---TSTDGyVLEgptstvviatddrLLTPPPWYGILPGTTQAALFEVAREKG-WDCEY 237
|
250
....*....|.
gi 2301398554 277 RKVTMKELKRA 287
Cdd:PRK07849 238 RALRPADLFAA 248
|
|
| PRK13356 |
PRK13356 |
branched-chain amino acid aminotransferase; |
83-318 |
8.96e-08 |
|
branched-chain amino acid aminotransferase;
Pssm-ID: 237362 Cd Length: 286 Bit Score: 52.65 E-value: 8.96e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 83 LNMDRMLRSARRLCL-PDFDKQELLECIRQ-LIEVDKDwvpdgngTSLYVRPVLIGNEPSLGVGMVTQALLYVILCPVGS 160
Cdd:PRK13356 52 LHCARVNRSAEALGLkPTVSAEEIEALAREgLKRFDPD-------TALYIRPMYWAEDGFASGVAPDPESTRFALCLEEA 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 161 YFPGDSMTPVSLladPSFVRAWIG-GVGDCKLGGNYGPTVAVQREAQKRGCEQVLWLYGPDHqLTEVGTMNIFVYwthED 239
Cdd:PRK13356 125 PMPEPTGFSLTL---SPFRRPTLEmAPTDAKAGCLYPNNARALREARSRGFDNALVLDMLGN-VAETATSNVFMV---KD 197
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2301398554 240 GVLelVTPPLNGVILPGVVRQSLLDLARTWGeFRVAERKVTMKELKRAleegrvREVFGSGTACQVCPVHQIlyEGKQL 318
Cdd:PRK13356 198 GVV--FTPVPNGTFLNGITRQRVIALLREDG-VTVVETTLTYEDFLEA------DEVFSTGNYSKVVPVTRF--DDRSL 265
|
|
| PRK12400 |
PRK12400 |
D-amino acid aminotransferase; Reviewed |
55-308 |
1.95e-07 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 171470 Cd Length: 290 Bit Score: 51.94 E-value: 1.95e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 55 GLHYSLQLFEGLKAYKGgdqQVRLFRPwlNMDRMLRSARR--LCLPdFDKQELLECIRQLIEvDKDWVPDGngtSLYVrp 132
Cdd:PRK12400 29 GLQFGDGVYEVIRLYKG---NFHLLDP--HITRLYRSMEEieLTLP-FSKAELITLLYKLIE-NNNFHEDG---TIYL-- 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 133 vlignEPSLGVGMVTQALLYVILCPVGSYfpgdsmtpVSLLADPSF-----VRA-------WIggvgDCKLGG-NYGPTV 199
Cdd:PRK12400 97 -----QVSRGVQARTHTFSYDVPPTIYAY--------ITKKERPALwieygVRAisepdtrWL----RCDIKSlNLLPNI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 200 AVQREAQKRGCEQVLWLYgpDHQLTEVGTMNIFVYwthEDGVLelVTPPLNGVILPGVVRQSLLDLARTWgEFRVAERKV 279
Cdd:PRK12400 160 LAATKAERKGCKEALFVR--NGTVTEGSHSNFFLI---KNGTL--YTHPANHLILNGIIRQYVLSLAKTL-RIPVQEELF 231
|
250 260
....*....|....*....|....*....
gi 2301398554 280 TMKELKRAleegrvREVFGSGTACQVCPV 308
Cdd:PRK12400 232 SVRDVYQA------DECFFTGTTIEILPM 254
|
|
| PRK06680 |
PRK06680 |
D-amino acid aminotransferase; Reviewed |
197-318 |
3.99e-07 |
|
D-amino acid aminotransferase; Reviewed
Pssm-ID: 180656 [Multi-domain] Cd Length: 286 Bit Score: 50.70 E-value: 3.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 197 PTVAVQREAQKRGCeQVLWLYGpDHQLTEVGTMNIFVywTHEDGVLelVTPPLNGVILPGVVRQSLLDLARTWGeFRVAE 276
Cdd:PRK06680 155 PNVLAKQAAKEAGA-QEAWMVD-DGFVTEGASSNAWI--VTKDGKL--VTRPADNFILPGITRHTLIDLAKELG-LEVEE 227
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 2301398554 277 RKVTMKELKRAleegrvREVFGSGTACQVCPVHQIlyEGKQL 318
Cdd:PRK06680 228 RPFTLQEAYAA------REAFITAASSFVFPVVQI--DGKQI 261
|
|
| PLN02845 |
PLN02845 |
Branched-chain-amino-acid aminotransferase-like protein |
194-289 |
1.04e-04 |
|
Branched-chain-amino-acid aminotransferase-like protein
Pssm-ID: 215454 [Multi-domain] Cd Length: 336 Bit Score: 43.46 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2301398554 194 NYGPTVAVQREAQKRGCEQVLWLYGpDHQLTEVGTMNI-FVywTHEDgvlELVTPPLNGvILPGVVRQSLLDLA---RTW 269
Cdd:PLN02845 188 NYLPNALSQMEAEERGAFAGIWLDE-EGFVAEGPNMNVaFL--TNDG---ELVLPPFDK-ILSGCTARRVLELAprlVSP 260
|
90 100
....*....|....*....|.
gi 2301398554 270 GEFR-VAERKVTMKELKRALE 289
Cdd:PLN02845 261 GDLRgVKQRKISVEEAKAADE 281
|
|
| PRK07546 |
PRK07546 |
hypothetical protein; Provisional |
222-287 |
4.66e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 169002 [Multi-domain] Cd Length: 209 Bit Score: 40.73 E-value: 4.66e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2301398554 222 QLTEVGTMNIFVywthEDGVLELVTPPLNGVILPGVVRQSLLDlartwgEFRVAERKVTMKELKRA 287
Cdd:PRK07546 136 EVCEGTITNVFL----DRGGGMLTTPPLSCGLLPGVLRAELLD------AGRAREAVLTVDDLKSA 191
|
|
| |
