NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|2470811938|ref|NP_001406140|]
View 

transmembrane protein 50A isoform b [Mus musculus]

Protein Classification

UPF0220 family protein( domain architecture ID 4022)

UPF0220 family protein similar to Homo sapiens transmembrane protein 50A/B and Saccharomyces cerevisiae vacuolar protein sorting-associated protein 68 (VPS68)

Gene Ontology:  GO:0032511
TCDB:  9.B.199

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
UPF0220 super family cl05018
Uncharacterized protein family (UPF0220); This family of proteins is functionally ...
 54-147 1.39e-32

Uncharacterized protein family (UPF0220); This family of proteins is functionally uncharacterized.


The actual alignment was detected with superfamily member pfam05255:

Pssm-ID: 428395  Cd Length: 160  Bit Score: 113.07  E-value: 1.39e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2470811938  54 FSSVG-LRINAVSNGQVRGDSysegcLGQTG------ARIWLFIGFMLAFGSLIASMWILFGGYVAKEKDV---VYPGIA 123
Cdd:pfam05255  61 CSTLGmLIVNSIEKSQLRGDS-----LGYTGsgvawkARVVLFLGFALLAGGLAGSVWVLILKYVVPGYTTyptLGMGVA 135

                          90       100
                  ....*....|....*....|....*
gi 2470811938 124 VFFQNAFIFFGGLVFKFGR-TEDLW 147
Cdd:pfam05255 136 NVLQNALIFLSSLVLWFGQnTEDEY 160
 
Name Accession Description Interval E-value
UPF0220 pfam05255
Uncharacterized protein family (UPF0220); This family of proteins is functionally ...
 54-147 1.39e-32

Uncharacterized protein family (UPF0220); This family of proteins is functionally uncharacterized.


Pssm-ID: 428395  Cd Length: 160  Bit Score: 113.07  E-value: 1.39e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2470811938  54 FSSVG-LRINAVSNGQVRGDSysegcLGQTG------ARIWLFIGFMLAFGSLIASMWILFGGYVAKEKDV---VYPGIA 123
Cdd:pfam05255  61 CSTLGmLIVNSIEKSQLRGDS-----LGYTGsgvawkARVVLFLGFALLAGGLAGSVWVLILKYVVPGYTTyptLGMGVA 135

                          90       100
                  ....*....|....*....|....*
gi 2470811938 124 VFFQNAFIFFGGLVFKFGR-TEDLW 147
Cdd:pfam05255 136 NVLQNALIFLSSLVLWFGQnTEDEY 160
 
Name Accession Description Interval E-value
UPF0220 pfam05255
Uncharacterized protein family (UPF0220); This family of proteins is functionally ...
 54-147 1.39e-32

Uncharacterized protein family (UPF0220); This family of proteins is functionally uncharacterized.


Pssm-ID: 428395  Cd Length: 160  Bit Score: 113.07  E-value: 1.39e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2470811938  54 FSSVG-LRINAVSNGQVRGDSysegcLGQTG------ARIWLFIGFMLAFGSLIASMWILFGGYVAKEKDV---VYPGIA 123
Cdd:pfam05255  61 CSTLGmLIVNSIEKSQLRGDS-----LGYTGsgvawkARVVLFLGFALLAGGLAGSVWVLILKYVVPGYTTyptLGMGVA 135

                          90       100
                  ....*....|....*....|....*
gi 2470811938 124 VFFQNAFIFFGGLVFKFGR-TEDLW 147
Cdd:pfam05255 136 NVLQNALIFLSSLVLWFGQnTEDEY 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH