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Conserved domains on  [gi|2563881426|ref|NP_001410759|]
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troponin T type 3b (skeletal, fast) isoform 5 [Danio rerio]

Protein Classification

troponin( domain architecture ID 12013160)

troponin such as troponin I (TnI, inhibitory) and T (TnT, tropomyosin binding) subunits, which together with troponin C (TnC, Ca2+ binding) subunit, form the troponin complex that regulates Ca2+ induced muscle contraction

CATH:  1.20.5.350
Gene Ontology:  GO:0005861|GO:0003009
PubMed:  18154728

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Troponin pfam00992
Troponin; Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and ...
 41-178 5.83e-15

Troponin; Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). this Pfam contains members of the TnT subunit. Troponin is a complex of three proteins, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). The troponin complex regulates Ca++ induced muscle contraction. This family includes troponin T and troponin I. Troponin I binds to actin and troponin T binds to tropomyosin.


:

Pssm-ID: 460018 [Multi-domain]  Cd Length: 132  Bit Score: 69.13  E-value: 5.83e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563881426  41 KRQNKDLVELQALIDAHFEHRKKEEEELIALKDRIEKRRSER--AEQQRIRAEKDKERQARREEERLRKEEADAKKRADE 118
Cdd:pfam00992   1 KRLLKSLLLQKAAEELEFEQEKKEEEKLRYLAERIPPLRLRGlsAEQLQELCEELHERIDKLEEERYDIEEKVAKKDKEI 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563881426 119 DAKKKSALSNMGsQYSSYLQKadskrgGKKQTEREKKKKILAERRKpLNIDHMNEDKLRE 178
Cdd:pfam00992  81 NDLKKKVNDLRG-KFKKPLLK------KVRKTADAMLKALLGSKHK-VSMDFRANLKQVK 132
 
Name Accession Description Interval E-value
Troponin pfam00992
Troponin; Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and ...
 41-178 5.83e-15

Troponin; Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). this Pfam contains members of the TnT subunit. Troponin is a complex of three proteins, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). The troponin complex regulates Ca++ induced muscle contraction. This family includes troponin T and troponin I. Troponin I binds to actin and troponin T binds to tropomyosin.


Pssm-ID: 460018 [Multi-domain]  Cd Length: 132  Bit Score: 69.13  E-value: 5.83e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563881426  41 KRQNKDLVELQALIDAHFEHRKKEEEELIALKDRIEKRRSER--AEQQRIRAEKDKERQARREEERLRKEEADAKKRADE 118
Cdd:pfam00992   1 KRLLKSLLLQKAAEELEFEQEKKEEEKLRYLAERIPPLRLRGlsAEQLQELCEELHERIDKLEEERYDIEEKVAKKDKEI 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563881426 119 DAKKKSALSNMGsQYSSYLQKadskrgGKKQTEREKKKKILAERRKpLNIDHMNEDKLRE 178
Cdd:pfam00992  81 NDLKKKVNDLRG-KFKKPLLK------KVRKTADAMLKALLGSKHK-VSMDFRANLKQVK 132
PhnG COG3624
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [Inorganic ion ...
 44-85 4.77e-03

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [Inorganic ion transport and metabolism];


Pssm-ID: 442842  Cd Length: 150  Bit Score: 36.36  E-value: 4.77e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2563881426  44 NKDLVELQALIDAHF---EHRKKEEEELIA-LKDRIEKRRSERAEQ 85
Cdd:COG3624    90 DKRHAELAAVLDALLqtpAHRAALEAALLApLAAARAARRAARAAE 135
 
Name Accession Description Interval E-value
Troponin pfam00992
Troponin; Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and ...
 41-178 5.83e-15

Troponin; Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). this Pfam contains members of the TnT subunit. Troponin is a complex of three proteins, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). The troponin complex regulates Ca++ induced muscle contraction. This family includes troponin T and troponin I. Troponin I binds to actin and troponin T binds to tropomyosin.


Pssm-ID: 460018 [Multi-domain]  Cd Length: 132  Bit Score: 69.13  E-value: 5.83e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563881426  41 KRQNKDLVELQALIDAHFEHRKKEEEELIALKDRIEKRRSER--AEQQRIRAEKDKERQARREEERLRKEEADAKKRADE 118
Cdd:pfam00992   1 KRLLKSLLLQKAAEELEFEQEKKEEEKLRYLAERIPPLRLRGlsAEQLQELCEELHERIDKLEEERYDIEEKVAKKDKEI 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 2563881426 119 DAKKKSALSNMGsQYSSYLQKadskrgGKKQTEREKKKKILAERRKpLNIDHMNEDKLRE 178
Cdd:pfam00992  81 NDLKKKVNDLRG-KFKKPLLK------KVRKTADAMLKALLGSKHK-VSMDFRANLKQVK 132
PhnG pfam06754
Phosphonate metabolism protein PhnG; This family consists of several bacterial phosphonate ...
 44-85 4.62e-03

Phosphonate metabolism protein PhnG; This family consists of several bacterial phosphonate metabolism protein PhnG sequences. In Escherichia coli, the phn operon encodes proteins responsible for the uptake and breakdown of phosphonates. The exact function of PhnG is unknown, however it is thought likely that along with six other proteins PhnG makes up the the C-P (carbon-phosphorus) lyase.


Pssm-ID: 429102  Cd Length: 135  Bit Score: 36.34  E-value: 4.62e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2563881426  44 NKDLVELQALIDAHF---EHRKKEEEELIA-LKDRIEKRRSERAEQ 85
Cdd:pfam06754  77 DKRHAELAALIDALLqdpLPGDELEEALIApLEARLAARRAARAAE 122
PhnG COG3624
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [Inorganic ion ...
 44-85 4.77e-03

Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG [Inorganic ion transport and metabolism];


Pssm-ID: 442842  Cd Length: 150  Bit Score: 36.36  E-value: 4.77e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 2563881426  44 NKDLVELQALIDAHF---EHRKKEEEELIA-LKDRIEKRRSERAEQ 85
Cdd:COG3624    90 DKRHAELAAVLDALLqtpAHRAALEAALLApLAAARAARRAARAAE 135
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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