|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
223-724 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 725.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 223 KPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTkgQLFMST 302
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 303 RaSKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYtGFKALKAGLLTE--TYLEAQF 380
Cdd:smart00350 79 R-STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPY-GFKLNTVKGLPVfaTYIEANH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 381 VRQ--HKKKFA----SFSLTSDVEERVM-ELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGD 453
Cdd:smart00350 157 VRKldYKRSFEdssfSVQSLSDEEEEEIrKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 454 INVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESD 533
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 534 RTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLA 613
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 614 EHVTYVHMHNK-QPDLDFT-PVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQDSkrEMDSKFSFGQATPRTLL 690
Cdd:smart00350 397 KHVVDLHRYSHpEEDEAFEpPLSQEKLRKYIAYAREKiKPKLSEEAADKLVKAYVDLRKED--SQTESRSSIPITVRQLE 474
|
490 500 510
....*....|....*....|....*....|....
gi 398365471 691 GIIRLSQALAKLRLADMVDIDDVEEALRLVRVSK 724
Cdd:smart00350 475 SIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
413-723 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 564.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRvGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVG 492
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 493 LTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYG 572
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 573 RYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVM 652
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTV 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 398365471 653 SEAVNDYVVQAYIRLRQDSKREMDSKFsfgqATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS 723
Cdd:cd17758 240 PPALADYIVQAYVEMRQEAKRSKDFTF----TTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
226-775 |
6.93e-167 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 500.10 E-value: 6.93e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 226 SVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECtsEECSQnqtKGQLFMSTRAS 305
Cdd:COG1241 95 PIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHEC--PGCGR---QGPFKLLPEKS 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 306 KFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAglLTETYLEAQFVRQHK 385
Cdd:COG1241 170 EFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKST--IFDLYLEANSIEVEE 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 386 KKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVA 465
Cdd:COG1241 248 KEFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTA 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 466 KSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKD-PVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQ 544
Cdd:COG1241 328 KSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFGTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQ 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 545 TISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMH-- 622
Cdd:COG1241 408 TISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAge 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 623 -NKQPDLDFT-----PVEPSKMREYIAYAK-TKRPVMSEAVNDYVVQAYIRLRQdSKREMDSKFSfgqATPRTLLGIIRL 695
Cdd:COG1241 488 lLEQEIEEETeevkpEIDPDLLRKYIAYARrNVFPVLTEEAKDLIEDFYVDMRK-KGEDEDSPVP---ITARQLEALIRL 563
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 696 SQALAKLRLADMVDIDDVEEALRLVRVSKESLYQ------------ETNKSKEDESPTTKIFTIIKKmLQETGKNTLSYE 763
Cdd:COG1241 564 AEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVdpetgkfdidviETGTSKSQRDKMKLIKDIIKE-LEEESSGGAPIE 642
|
570
....*....|..
gi 398365471 764 NIVKTVRLRGFT 775
Cdd:COG1241 643 DVIEEAEEEGID 654
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
134-774 |
2.59e-152 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 462.47 E-value: 2.59e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 134 YKDDVLDVILNQRRlrneRMLSDRTNEIR-SENLMDTTMDPPS----SMNDALREVVEDETELFPpNLTRRYFLYFKPLS 208
Cdd:NF040949 21 YKERIFEMIAMRKR----SLVVDFNDLYMfDPELADLLIEKPDevlpAASKALKEIVEEEDPEYA-EEVAKFHVRFRNLP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 209 QNcarryrkkaisskpLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVF-----QEVNSRTFTPLse 283
Cdd:NF040949 96 RT--------------VPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEwpeeeEESYEIVEPPT-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 284 cTSEECSQNqtkGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGF 363
Cdd:NF040949 160 -VCPVCGKP---GSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 364 KALKAGLLtETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKR 443
Cdd:NF040949 236 KKGSRPIF-KNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 444 VGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCI 523
Cdd:NF040949 315 LPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 524 DEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDI 603
Cdd:NF040949 395 DEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDK 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 604 PSRDDDEKLAEHVTYVHmhnkQPDLDFTP-VEPSKMREYIAYA-KTKRPVMSEAVNDYVVQAYIRLRQDSK--REMDSKF 679
Cdd:NF040949 475 PNEERDRRLARHILDVH----SGKEKVKPeIDPDLLKKYIAYArKYVRPKLTEEAKKLIEDFYVEMRKSSKssEDPDSPI 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 680 SFgqaTPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESL------------YQETNKSKEDESPTTKIFTI 747
Cdd:NF040949 551 PI---TARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVgidvetgkididTIMTGKPKSKREKMSKIVEI 627
|
650 660
....*....|....*....|....*..
gi 398365471 748 IKKMLQETGKNTLsyENIVKTVRLRGF 774
Cdd:NF040949 628 IKELEEEEECVKI--KELIKEAEKKGI 652
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
398-620 |
3.00e-130 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 388.43 E-value: 3.00e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 398 EERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKIS 477
Cdd:pfam00493 2 EEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 478 PRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTL 557
Cdd:pfam00493 82 PRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398365471 558 NARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVH 620
Cdd:pfam00493 162 NARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
179-723 |
2.11e-76 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 266.86 E-value: 2.11e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 179 DALREVVEDETELFPPNLTRRY-FLYFKPLSQNCARRYRKKAISSkplSVRQIKGDFLGQLITVRGIITRVSDVKPAVEV 257
Cdd:PTZ00111 172 DCIAELDKVLVKLFNELLSKHYsDLSLENNSFFPRARLMNKPVSD---CVGNLEPSMADSLVQFSGTVVRQTWIVPEITM 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 258 IAYTC-----------DQCGYEVFQEV-NSRTFTPLSectseeCSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVG 325
Cdd:PTZ00111 249 ACFRCrgqkkiglndyQPCTCEHYEYViQGEVNEPLL------CNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNP 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 326 HIP--------------------RSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY---TGFKALKAglLTETYLEAQFVR 382
Cdd:PTZ00111 323 DKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIrtsTTRRTLKS--LYTYFVNVIHVK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 383 --------QHKKKFASFS----LTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKK-----ALLLLLVGGVDKRVG 445
Cdd:PTZ00111 401 vinstnanQPEKGLKYLGnendFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIgllcqLFSGNKNSSDFNKSP 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 446 DGM----KIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAV-MKDPVTDEMILEGGALVLADNGI 520
Cdd:PTZ00111 481 DACykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGV 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 521 CCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM 600
Cdd:PTZ00111 561 CCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLV 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 601 LDIPSRDDDEKLA---------EHVTYVH-----------MHNK----QPDLDFTPVEPSKMREYIAYAK-TKRPVMSEA 655
Cdd:PTZ00111 641 LDHIDQDTDQLISlsiakdfllPHMTGSGndedtydrsntMHVEdeslRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDE 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 656 VNDYVVQAYIRLRQ-----------DSKREMDSKFSFGQ--------ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEA 716
Cdd:PTZ00111 721 AKKVITREYVKMRQgnfqtsnldelEHAQEDDDDDLYYQssgtrmiyVSSRMISSIIRISVSLARMRLSTVVTPADALQA 800
|
....*..
gi 398365471 717 LRLVRVS 723
Cdd:PTZ00111 801 VQIVKSS 807
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
59-138 |
1.63e-07 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 49.98 E-value: 1.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 59 KGPKYMAMLQKVANRELNSVIIDLDDILQYQNekflqgtqadDLVSAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDV 138
Cdd:pfam14551 17 GEFKYRDQLREMIEREQRSLEVDLDDLREFDP----------DLAEALLENPYEYLPLFEEALKEVVKELSEDPDYAEEE 86
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
223-724 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 725.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 223 KPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTkgQLFMST 302
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 303 RaSKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYtGFKALKAGLLTE--TYLEAQF 380
Cdd:smart00350 79 R-STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVPY-GFKLNTVKGLPVfaTYIEANH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 381 VRQ--HKKKFA----SFSLTSDVEERVM-ELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGD 453
Cdd:smart00350 157 VRKldYKRSFEdssfSVQSLSDEEEEEIrKLSKDPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNLPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 454 INVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESD 533
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 534 RTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLA 613
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 614 EHVTYVHMHNK-QPDLDFT-PVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQDSkrEMDSKFSFGQATPRTLL 690
Cdd:smart00350 397 KHVVDLHRYSHpEEDEAFEpPLSQEKLRKYIAYAREKiKPKLSEEAADKLVKAYVDLRKED--SQTESRSSIPITVRQLE 474
|
490 500 510
....*....|....*....|....*....|....
gi 398365471 691 GIIRLSQALAKLRLADMVDIDDVEEALRLVRVSK 724
Cdd:smart00350 475 SIIRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
413-723 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 564.34 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRvGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVG 492
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKR-GDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 493 LTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYG 572
Cdd:cd17758 80 LTAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 573 RYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVM 652
Cdd:cd17758 160 RYNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTV 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 398365471 653 SEAVNDYVVQAYIRLRQDSKREMDSKFsfgqATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS 723
Cdd:cd17758 240 PPALADYIVQAYVEMRQEAKRSKDFTF----TTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
226-775 |
6.93e-167 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 500.10 E-value: 6.93e-167
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 226 SVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECtsEECSQnqtKGQLFMSTRAS 305
Cdd:COG1241 95 PIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHEC--PGCGR---QGPFKLLPEKS 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 306 KFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAglLTETYLEAQFVRQHK 385
Cdd:COG1241 170 EFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGILRIEQRTSGRGKST--IFDLYLEANSIEVEE 247
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 386 KKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVA 465
Cdd:COG1241 248 KEFEEIEITEEDEEKIKELSKDPDIYEKIIASIAPSIYGYEEIKEAIALQLFGGVPKVLPDGSRIRGDIHILLVGDPGTA 327
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 466 KSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKD-PVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQ 544
Cdd:COG1241 328 KSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDdFGTGRWTLEAGALVLADGGLACIDELDKMREEDRSALHEAMEQQ 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 545 TISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMH-- 622
Cdd:COG1241 408 TISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEERDRELARHILKVHRAge 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 623 -NKQPDLDFT-----PVEPSKMREYIAYAK-TKRPVMSEAVNDYVVQAYIRLRQdSKREMDSKFSfgqATPRTLLGIIRL 695
Cdd:COG1241 488 lLEQEIEEETeevkpEIDPDLLRKYIAYARrNVFPVLTEEAKDLIEDFYVDMRK-KGEDEDSPVP---ITARQLEALIRL 563
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 696 SQALAKLRLADMVDIDDVEEALRLVRVSKESLYQ------------ETNKSKEDESPTTKIFTIIKKmLQETGKNTLSYE 763
Cdd:COG1241 564 AEASARMRLSDTVTEEDAERAIRLVDSCLKDVGVdpetgkfdidviETGTSKSQRDKMKLIKDIIKE-LEEESSGGAPIE 642
|
570
....*....|..
gi 398365471 764 NIVKTVRLRGFT 775
Cdd:COG1241 643 DVIEEAEEEGID 654
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
413-723 |
6.10e-155 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 455.26 E-value: 6.10e-155
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVG 492
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKILEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 493 LTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYG 572
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 573 RYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNK-----QPDLDFTPVEPSKMREYIAYAKT 647
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSDpeeqvKPEEDGIPIDIELLRKYILYARQ 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 398365471 648 KRPVMSEAVNDYVVQAYIRLRQDSKREmdskfSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS 723
Cdd:cd17706 241 IHPKISEEAREKLVRWYVELRKESERR-----STIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
134-774 |
2.59e-152 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 462.47 E-value: 2.59e-152
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 134 YKDDVLDVILNQRRlrneRMLSDRTNEIR-SENLMDTTMDPPS----SMNDALREVVEDETELFPpNLTRRYFLYFKPLS 208
Cdd:NF040949 21 YKERIFEMIAMRKR----SLVVDFNDLYMfDPELADLLIEKPDevlpAASKALKEIVEEEDPEYA-EEVAKFHVRFRNLP 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 209 QNcarryrkkaisskpLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVF-----QEVNSRTFTPLse 283
Cdd:NF040949 96 RT--------------VPLRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEwpeeeEESYEIVEPPT-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 284 cTSEECSQNqtkGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGF 363
Cdd:NF040949 160 -VCPVCGKP---GSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 364 KALKAGLLtETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKR 443
Cdd:NF040949 236 KKGSRPIF-KNYIEANHIEVSQKELEEVEITEEDEEKILELAKDPWIREKIIASIAPSIYGHWEIKEAIALLLFGGVPKV 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 444 VGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCI 523
Cdd:NF040949 315 LPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVAVI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 524 DEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDI 603
Cdd:NF040949 395 DEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIRDK 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 604 PSRDDDEKLAEHVTYVHmhnkQPDLDFTP-VEPSKMREYIAYA-KTKRPVMSEAVNDYVVQAYIRLRQDSK--REMDSKF 679
Cdd:NF040949 475 PNEERDRRLARHILDVH----SGKEKVKPeIDPDLLKKYIAYArKYVRPKLTEEAKKLIEDFYVEMRKSSKssEDPDSPI 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 680 SFgqaTPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESL------------YQETNKSKEDESPTTKIFTI 747
Cdd:NF040949 551 PI---TARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLMLAFLESVgidvetgkididTIMTGKPKSKREKMSKIVEI 627
|
650 660
....*....|....*....|....*..
gi 398365471 748 IKKMLQETGKNTLsyENIVKTVRLRGF 774
Cdd:NF040949 628 IKELEEEEECVKI--KELIKEAEKKGI 652
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
398-620 |
3.00e-130 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 388.43 E-value: 3.00e-130
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 398 EERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKIS 477
Cdd:pfam00493 2 EEEIKELAKRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGGVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 478 PRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTL 557
Cdd:pfam00493 82 PRAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATL 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 398365471 558 NARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVH 620
Cdd:pfam00493 162 NARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
413-723 |
1.17e-125 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 380.19 E-value: 1.17e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVG 492
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRLPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 493 LTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYG 572
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 573 RYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMhNKQPDLDFTPVEP----SKMREYIAYAKTK 648
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHA-SARKASQSQENEGeipiSKLKRYIAYCRAK 239
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 398365471 649 -RPVMSEAVNDYVVQAYIRLRQDSKR-EMDSKFSFG-QATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS 723
Cdd:cd17756 240 cAPRLSEEAAEKLSNHYVTIRKDVRQnELESDNRSSiPITVRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
413-723 |
6.63e-123 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 372.86 E-value: 6.63e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVG 492
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGGVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 493 LTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYG 572
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 573 RYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHM-HNKQPDLDFTPVEpskMREYIAYAKTKRPV 651
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHIVDLHSkREEAIEPPFTAEQ---LKRYIAYARTFKPK 237
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 398365471 652 MSEAVNDYVVQAYIRLRQDSKREMDSKfSFgQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS 723
Cdd:cd17757 238 LTKEAKDELVEQYKELRQDDASGSTRS-SY-RITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
413-723 |
2.48e-118 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 360.98 E-value: 2.48e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGD-GMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGV 491
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLFGGTRKDFTKtGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 492 GLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLY 571
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 572 GRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTK-RP 650
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEVLDVEVLTDYISYAREHiHP 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 398365471 651 VMSEAVNDYVVQAYIRLRQ--DSKREMDSkfsfgqATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS 723
Cdd:cd17755 241 KLSEEAAQELVQAYVDMRKmgSDARKRIT------ATPRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLIREA 309
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
413-721 |
1.35e-109 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 338.27 E-value: 1.35e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVG 492
Cdd:cd17761 2 KIISSIAPSIYGHEDVKEAIALQLFGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAAG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 493 LTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYG 572
Cdd:cd17761 82 LTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKFG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 573 RYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVH----MHNKQPDLDftpvePSKMREYIAYA-KT 647
Cdd:cd17761 162 RFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHsggeMREIKPEID-----PDLLRKYIAYArKN 236
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 398365471 648 KRPVMSEAVNDYVVQAYIRLRqdsKREMDSKFSFgQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVR 721
Cdd:cd17761 237 VRPVLTEEAKQLIKDFYVEMR---KSGQETPSPV-PITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIML 306
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
414-721 |
3.79e-109 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 336.75 E-value: 3.79e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 414 LAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGL 493
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNLENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 494 TAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGR 573
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 574 YNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKqpdldFtpvepskMREYIAYAKTK-RPVM 652
Cdd:cd17754 162 YDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRYIK-----F-------LRKYIHYAKERiKPKL 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 398365471 653 SEAVNDYVVQAYIRLRQDSKREMDSKFSFgQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVR 721
Cdd:cd17754 230 TQEAAEYIAEEYADLRNDDNTKTDKARTS-PITARTLETLIRLATAHAKARLSKTVDKVDAEVALNLLR 297
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
413-720 |
1.08e-107 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 334.03 E-value: 1.08e-107
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVG 492
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKHRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 493 LTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYG 572
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 573 RYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHN-----KQPDLDFTPVEPSK---------- 637
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFVVGSHVRShpendEDREGEEEKNQRQRpketkvepip 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 638 ---MREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQDSkremdSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDV 713
Cdd:cd17753 241 qelLRKYIHYAREKvRPKLNQMDMDKVSRVYADLRKES-----MATGSLPITVRHLESIIRISEAHAKMHLREYVSEEDV 315
|
....*..
gi 398365471 714 EEALRLV 720
Cdd:cd17753 316 DMAIRVM 322
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
413-723 |
6.11e-77 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 251.30 E-value: 6.11e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 413 RLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMK--IRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSG 490
Cdd:cd17759 1 LIVNSLCPAIYGHELVKAGLLLSLFGGKQKYADDKNRipIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 491 VGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDeSDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPL 570
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMG-SQHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 571 YGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHvtyvhmhnkqPDLdftpvepskMREYIAYAKTK-R 649
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH----------HQL---------LRKYISYARQYvN 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 398365471 650 PVMSEAVNDYVVQAYIRLRQDSKREMDSkfsfgQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS 723
Cdd:cd17759 221 PVLSKDASEALQEFYLELRKQNQLADSS-----PITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
179-723 |
2.11e-76 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 266.86 E-value: 2.11e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 179 DALREVVEDETELFPPNLTRRY-FLYFKPLSQNCARRYRKKAISSkplSVRQIKGDFLGQLITVRGIITRVSDVKPAVEV 257
Cdd:PTZ00111 172 DCIAELDKVLVKLFNELLSKHYsDLSLENNSFFPRARLMNKPVSD---CVGNLEPSMADSLVQFSGTVVRQTWIVPEITM 248
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 258 IAYTC-----------DQCGYEVFQEV-NSRTFTPLSectseeCSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVG 325
Cdd:PTZ00111 249 ACFRCrgqkkiglndyQPCTCEHYEYViQGEVNEPLL------CNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNP 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 326 HIP--------------------RSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY---TGFKALKAglLTETYLEAQFVR 382
Cdd:PTZ00111 323 DKDgldnsvdnsglngeiymkdnEVINLNLYDDLIDSVKTGDRVTVVGILKVTPIrtsTTRRTLKS--LYTYFVNVIHVK 400
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 383 --------QHKKKFASFS----LTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKK-----ALLLLLVGGVDKRVG 445
Cdd:PTZ00111 401 vinstnanQPEKGLKYLGnendFSDLQVYKILELSRNPMIYRILLDSFAPSIKARNNVKIgllcqLFSGNKNSSDFNKSP 480
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 446 DGM----KIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAV-MKDPVTDEMILEGGALVLADNGI 520
Cdd:PTZ00111 481 DACykvdNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGV 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 521 CCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM 600
Cdd:PTZ00111 561 CCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLV 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 601 LDIPSRDDDEKLA---------EHVTYVH-----------MHNK----QPDLDFTPVEPSKMREYIAYAK-TKRPVMSEA 655
Cdd:PTZ00111 641 LDHIDQDTDQLISlsiakdfllPHMTGSGndedtydrsntMHVEdeslRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDE 720
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 656 VNDYVVQAYIRLRQ-----------DSKREMDSKFSFGQ--------ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEA 716
Cdd:PTZ00111 721 AKKVITREYVKMRQgnfqtsnldelEHAQEDDDDDLYYQssgtrmiyVSSRMISSIIRISVSLARMRLSTVVTPADALQA 800
|
....*..
gi 398365471 717 LRLVRVS 723
Cdd:PTZ00111 801 VQIVKSS 807
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
414-723 |
1.92e-67 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 226.27 E-value: 1.92e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 414 LAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGL 493
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAGGVQRIDASGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 494 TAAVMKDpvTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPlYGR 573
Cdd:cd17760 82 TVTAVKD--GGEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNP-KGQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 574 YNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVtyvhMHNK-QPDLDFTPVEPSKMREYIAYAKTKRPVM 652
Cdd:cd17760 159 YDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFI----LENKgEPSKSSKLWSMEKMRTYFCLIKNLRPVL 234
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 398365471 653 SEAVNDYVVQAYIRLRQDSKREMdskfsfGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVS 723
Cdd:cd17760 235 SDEANAILLRYYQLQRQSDCRNA------ARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
226-359 |
9.50e-43 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 151.48 E-value: 9.50e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 226 SVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEvnsrtFTPLSECTSEECsqnQTKGQLFMSTRAS 305
Cdd:pfam17207 1 SIRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVK-----ITEPTKCPNPEC---GNKDPFKLVHEKS 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 398365471 306 KFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAP 359
Cdd:pfam17207 73 KFVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVVP 126
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
636-724 |
4.24e-27 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 105.32 E-value: 4.24e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 636 SKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQDSkremDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVE 714
Cdd:pfam17855 1 ELLRKYIAYAREKiKPKLSEEAREKLVDAYVELRKES----TGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVE 76
|
90
....*....|
gi 398365471 715 EALRLVRVSK 724
Cdd:pfam17855 77 EAIRLLKESL 86
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
458-720 |
1.82e-10 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 62.88 E-value: 1.82e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 458 LMGDPGVAKSQLLKAICK---ISPRGVYTTG--KGSSGVGLTAAVMKDpvTDEMILEG---GALVLADngiccidEFDKM 529
Cdd:COG0714 36 LEGVPGVGKTTLAKALARalgLPFIRIQFTPdlLPSDILGTYIYDQQT--GEFEFRPGplfANVLLAD-------EINRA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 530 DEsdRT--AIHEVMEQQTISIskAGINTTLNARTSILAAANPL--YGRYNprlspldninLPAALLSRFdILFLMLDIPS 605
Cdd:COG0714 107 PP--KTqsALLEAMEERQVTI--PGGTYKLPEPFLVIATQNPIeqEGTYP----------LPEAQLDRF-LLKLYIGYPD 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 606 RDDDEKLAEHVTYVHMHNKQPDLDftPVEPSKMREYIAyaktkRPVMSEAVNDYVVQAYIRLRQDSKremdskFSFGqAT 685
Cdd:COG0714 172 AEEEREILRRHTGRHLAEVEPVLS--PEELLALQELVR-----QVHVSEAVLDYIVDLVRATREHPD------LRKG-PS 237
|
250 260 270
....*....|....*....|....*....|....*
gi 398365471 686 PRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720
Cdd:COG0714 238 PRASIALLRAARALALLDGRDYVTPDDVKAVAGPV 272
|
|
| MCM_N |
pfam14551 |
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins. |
59-138 |
1.63e-07 |
|
MCM N-terminal domain; This family contains the N-terminal domain of MCM proteins.
Pssm-ID: 464206 [Multi-domain] Cd Length: 95 Bit Score: 49.98 E-value: 1.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 59 KGPKYMAMLQKVANRELNSVIIDLDDILQYQNekflqgtqadDLVSAIQQNANHFTELFCRAIDNNMPLPTKEIDYKDDV 138
Cdd:pfam14551 17 GEFKYRDQLREMIEREQRSLEVDLDDLREFDP----------DLAEALLENPYEYLPLFEEALKEVVKELSEDPDYAEEE 86
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
455-594 |
3.33e-06 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 47.29 E-value: 3.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 455 NVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSgvGLTAAVMKDPV---TDEMILEGGALVLADN--GICCIDEFDKM 529
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLTR--DTTEEDLFGRRnidPGGASWVDGPLVRAARegEIAVLDEINRA 78
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 398365471 530 DESDRTAIHEVMEQQTISISKAGinTTLNAR---TSILAAANPLYGRYNPrlspldninLPAALLSRF 594
Cdd:pfam07728 79 NPDVLNSLLSLLDERRLLLPDGG--ELVKAApdgFRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| PRK09862 |
PRK09862 |
ATP-dependent protease; |
507-604 |
3.39e-04 |
|
ATP-dependent protease;
Pssm-ID: 182120 [Multi-domain] Cd Length: 506 Bit Score: 44.20 E-value: 3.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 507 ILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANP-----LYGRYNpRLSPL 581
Cdd:PRK09862 284 IPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITYPARFQLVAAMNPsptghYQGNHN-RCTPE 362
|
90 100
....*....|....*....|....*..
gi 398365471 582 DNI----NLPAALLSRFDilfLMLDIP 604
Cdd:PRK09862 363 QTLrylnRLSGPFLDRFD---LSLEIP 386
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
455-600 |
6.79e-03 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 37.90 E-value: 6.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 455 NVCLMGDPGVAKSQLLKAICKISPRG----VYTTGKGSSGVGLTAAVMKDPVTDEMIlegGALVLADNGICCIDEFDKMD 530
Cdd:cd00009 21 NLLLYGPPGTGKTTLARAIANELFRPgapfLYLNASDLLEGLVVAELFGHFLVRLLF---ELAEKAKPGVLFIDEIDSLS 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 531 ESDRTAIHEVMEQQTISIskagintTLNARTSILAAANplygryNPRLSPLDNinlpaALLSRFDILFLM 600
Cdd:cd00009 98 RGAQNALLRVLETLNDLR-------IDRENVRVIGATN------RPLLGDLDR-----ALYDRLDIRIVI 149
|
|
| PRK10787 |
PRK10787 |
DNA-binding ATP-dependent protease La; Provisional |
449-625 |
8.34e-03 |
|
DNA-binding ATP-dependent protease La; Provisional
Pssm-ID: 182730 [Multi-domain] Cd Length: 784 Bit Score: 39.92 E-value: 8.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 449 KIRGDInVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGssGVGLTAAVMKDPVT--DEM---ILEGGALVLADNGICCI 523
Cdd:PRK10787 346 KIKGPI-LCLVGPPGVGKTSLGQSIAKATGRKYVRMALG--GVRDEAEIRGHRRTyiGSMpgkLIQKMAKVGVKNPLFLL 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365471 524 DEFDKMDESDR----TAIHEVME-QQTISISKAGINTTLNARTSILAAANplygrynprlsplDNINLPAALLSRFDILF 598
Cdd:PRK10787 423 DEIDKMSSDMRgdpaSALLEVLDpEQNVAFSDHYLEVDYDLSDVMFVATS-------------NSMNIPAPLLDRMEVIR 489
|
170 180
....*....|....*....|....*..
gi 398365471 599 LmldiPSRDDDEKLaeHVTYVHMHNKQ 625
Cdd:PRK10787 490 L----SGYTEDEKL--NIAKRHLLPKQ 510
|
|
| |
