NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|398365419|ref|NP_012646|]
View 

MIND complex subunit NNF1 [Saccharomyces cerevisiae S288C]

Protein Classification

PMF1/NNF1 family protein( domain architecture ID 10512497)

PMF1/NNF1 family protein similar to Homo sapiens polyamine-modulated factor 1 (PMF1) and Saccharomyces cerevisiae kinetochore-associated protein NNF1

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Nnf1 pfam03980
Nnf1; NNF1 is an essential yeast gene that is necessary for chromosome segregation. It is ...
 49-155 1.61e-27

Nnf1; NNF1 is an essential yeast gene that is necessary for chromosome segregation. It is associated with the spindle poles and forms part of a kinetochore subcomplex called MIND.


:

Pssm-ID: 461118  Cd Length: 103  Bit Score: 100.01  E-value: 1.61e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365419   49 NVANCQRQLTEFWTELCQREFKEIMEERNVEQKLNELDELILEAKERytdrdQDEVNKGPAIDELSSKELVECHLYSQRM 128
Cdd:pfam03980   2 SLESVHRQMVEFLQESCREEFEEILEERDVVAKLNELDELIEEAKER-----REEGEGPAWRPSVPPEELIRAHLAPYKQ 76

                          90       100
                  ....*....|....*....|....*..
gi 398365419  129 HAIHEIDERLAKVNEMNDQLAQELKDL 155
Cdd:pfam03980  77 KQLEQLNARLQKLEAENAALAEEVQAQ 103
 
Name Accession Description Interval E-value
Nnf1 pfam03980
Nnf1; NNF1 is an essential yeast gene that is necessary for chromosome segregation. It is ...
 49-155 1.61e-27

Nnf1; NNF1 is an essential yeast gene that is necessary for chromosome segregation. It is associated with the spindle poles and forms part of a kinetochore subcomplex called MIND.


Pssm-ID: 461118  Cd Length: 103  Bit Score: 100.01  E-value: 1.61e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365419   49 NVANCQRQLTEFWTELCQREFKEIMEERNVEQKLNELDELILEAKERytdrdQDEVNKGPAIDELSSKELVECHLYSQRM 128
Cdd:pfam03980   2 SLESVHRQMVEFLQESCREEFEEILEERDVVAKLNELDELIEEAKER-----REEGEGPAWRPSVPPEELIRAHLAPYKQ 76

                          90       100
                  ....*....|....*....|....*..
gi 398365419  129 HAIHEIDERLAKVNEMNDQLAQELKDL 155
Cdd:pfam03980  77 KQLEQLNARLQKLEAENAALAEEVQAQ 103
 
Name Accession Description Interval E-value
Nnf1 pfam03980
Nnf1; NNF1 is an essential yeast gene that is necessary for chromosome segregation. It is ...
 49-155 1.61e-27

Nnf1; NNF1 is an essential yeast gene that is necessary for chromosome segregation. It is associated with the spindle poles and forms part of a kinetochore subcomplex called MIND.


Pssm-ID: 461118  Cd Length: 103  Bit Score: 100.01  E-value: 1.61e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365419   49 NVANCQRQLTEFWTELCQREFKEIMEERNVEQKLNELDELILEAKERytdrdQDEVNKGPAIDELSSKELVECHLYSQRM 128
Cdd:pfam03980   2 SLESVHRQMVEFLQESCREEFEEILEERDVVAKLNELDELIEEAKER-----REEGEGPAWRPSVPPEELIRAHLAPYKQ 76

                          90       100
                  ....*....|....*....|....*..
gi 398365419  129 HAIHEIDERLAKVNEMNDQLAQELKDL 155
Cdd:pfam03980  77 KQLEQLNARLQKLEAENAALAEEVQAQ 103
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 77-200 7.22e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 36.62  E-value: 7.22e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 398365419   77 NVEQKLNELDELILEAKERYTDRDQDEvnkgPAIDELSSKELVECHLYSQRMHAIHEIDERLAKVNEMNDQLAQELKDLE 156
Cdd:pfam05483 402 NKEVELEELKKILAEDEKLLDEKKQFE----KIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLK 477

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 398365419  157 TQVEVEkneigKMYDEYLGSHTDQPA--NVLLVQSLNDMVLELKEN 200
Cdd:pfam05483 478 TELEKE-----KLKNIELTAHCDKLLleNKELTQEASDMTLELKKH 518
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH