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Conserved domains on  [gi|80861401|ref|NP_036828|]
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T-kininogen 1 precursor [Rattus norvegicus]

Protein Classification

cystatin family protein( domain architecture ID 11249387)

cystatin family protein similar to cystatins which are a family of cysteine protease inhibitors

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 262-370 4.97e-32

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 214484  Cd Length: 107  Bit Score: 117.53  E-value: 4.97e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401    262 NCRGCPREIPVDSPELKEALGHSIAQLNAQHNHIFYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSktELTADCET 341
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPF 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 80861401    342 KHLGQsLNCNANVYMRPWENK-VVPTVRCQ 370
Cdd:smart00043  79 LDQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 140-248 1.96e-28

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 214484  Cd Length: 107  Bit Score: 107.90  E-value: 1.96e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401    140 LCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKEDfpSLREDCVP 219
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPF 78

                           90       100
                   ....*....|....*....|....*....
gi 80861401    220 LPYGDHGECTGHTHVDIHNTIAGFSQSCD 248
Cdd:smart00043  79 LDQGEKFCTAKVWEKPWENKIKLVEFKCT 107
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 21-125 1.42e-18

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 214484  Cd Length: 107  Bit Score: 80.55  E-value: 1.42e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401     21 EGAQELNCNDETVFQAVDTALKKYNAELESGNQFVLYRVTKGTKKDGAETLYSFKYQIKEGNCSVQSGLtWQDCDFKDAE 100
Cdd:smart00043   4 GGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQG 82

                           90       100
                   ....*....|....*....|....*..
gi 80861401    101 EaatGECTTTLGKK--ENKFSVATQIC 125
Cdd:smart00043  83 E---KFCTAKVWEKpwENKIKLVEFKC 106
 
Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 262-370 4.97e-32

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 117.53  E-value: 4.97e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401    262 NCRGCPREIPVDSPELKEALGHSIAQLNAQHNHIFYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSktELTADCET 341
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPF 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 80861401    342 KHLGQsLNCNANVYMRPWENK-VVPTVRCQ 370
Cdd:smart00043  79 LDQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 265-369 3.51e-29

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 109.87  E-value: 3.51e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401 265 GCPREIPVDSPELKEALGHSIAQLNAQHNHIfYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSKTELTADCETKHL 344
Cdd:cd00042   1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 80861401 345 GQSLNCNANVYMRPWEN-KVVPTVRC 369
Cdd:cd00042  80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 140-248 1.96e-28

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 107.90  E-value: 1.96e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401    140 LCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKEDfpSLREDCVP 219
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPF 78

                           90       100
                   ....*....|....*....|....*....
gi 80861401    220 LPYGDHGECTGHTHVDIHNTIAGFSQSCD 248
Cdd:smart00043  79 LDQGEKFCTAKVWEKPWENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-237 4.84e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 106.26  E-value: 4.84e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401   143 GCFQPIPMDSSDLKPVLKHAVEHFNNNTkHTHLFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKedFPSLREDCVPLPY 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 80861401   223 GDHGECTGHTHVDIH 237
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 265-359 4.84e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 106.26  E-value: 4.84e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401   265 GCPREIPVDSPELKEALGHSIAQLNAQhNHIFYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSKteLTADCETKHL 344
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAK-TDNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSKSKK--LLEDCPLLDE 77

                          90
                  ....*....|....*
gi 80861401   345 GQSLNCNANVYMRPW 359
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 143-247 2.85e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 101.78  E-value: 2.85e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401 143 GCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHlFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPSLREDCVPLPY 222
Cdd:cd00042   1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 80861401 223 GDHGECTGHTHVDIH-NTIAGFSQSC 247
Cdd:cd00042  80 GKKKFCTAKVWEKPWeNFKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 21-125 1.42e-18

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 80.55  E-value: 1.42e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401     21 EGAQELNCNDETVFQAVDTALKKYNAELESGNQFVLYRVTKGTKKDGAETLYSFKYQIKEGNCSVQSGLtWQDCDFKDAE 100
Cdd:smart00043   4 GGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQG 82

                           90       100
                   ....*....|....*....|....*..
gi 80861401    101 EaatGECTTTLGKK--ENKFSVATQIC 125
Cdd:smart00043  83 E---KFCTAKVWEKpwENKIKLVEFKC 106
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 22-114 1.01e-16

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 75.06  E-value: 1.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401    22 GAQELNCNDETVFQAVDTALKKYNAElESGNQFVLYRVTKGTKKDGAETLYSFKYQIKEGNCSVqSGLTWQDCDFKDaeE 101
Cdd:pfam00031   2 GLSPIPDNSPELQEALDFALAEYNAK-TDNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--E 77

                          90
                  ....*....|...
gi 80861401   102 AATGECTTTLGKK 114
Cdd:pfam00031  78 KWLGLCSAQVYKV 90
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 22-125 3.72e-07

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 48.24  E-value: 3.72e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401  22 GAQELNCNDETVFQAVDTALKKYNAELESGNqFVLYRVTKGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQdCDFKDAEE 101
Cdd:cd00042   2 GPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDC-PDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 80861401 102 AATGECTTTLGKK--ENKFSVATQIC 125
Cdd:cd00042  80 GKKKFCTAKVWEKpwENFKELLSFKC 105
 
Name Accession Description Interval E-value
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 262-370 4.97e-32

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 117.53  E-value: 4.97e-32
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401    262 NCRGCPREIPVDSPELKEALGHSIAQLNAQHNHIFYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSktELTADCET 341
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPF 78

                           90       100       110
                   ....*....|....*....|....*....|
gi 80861401    342 KHLGQsLNCNANVYMRPWENK-VVPTVRCQ 370
Cdd:smart00043  79 LDQGE-KFCTAKVWEKPWENKiKLVEFKCT 107
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 265-369 3.51e-29

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 109.87  E-value: 3.51e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401 265 GCPREIPVDSPELKEALGHSIAQLNAQHNHIfYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSKTELTADCETKHL 344
Cdd:cd00042   1 GGPSDIPANDPEVQELADFAVAEYNKKSNDK-YLEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 80861401 345 GQSLNCNANVYMRPWEN-KVVPTVRC 369
Cdd:cd00042  80 GKKKFCTAKVWEKPWENfKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 140-248 1.96e-28

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 107.90  E-value: 1.96e-28
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401    140 LCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKEDfpSLREDCVP 219
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLS--VDLENCPF 78

                           90       100
                   ....*....|....*....|....*....
gi 80861401    220 LPYGDHGECTGHTHVDIHNTIAGFSQSCD 248
Cdd:smart00043  79 LDQGEKFCTAKVWEKPWENKIKLVEFKCT 107
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 143-237 4.84e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 106.26  E-value: 4.84e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401   143 GCFQPIPMDSSDLKPVLKHAVEHFNNNTkHTHLFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKedFPSLREDCVPLPY 222
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAKT-DNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK--SKKLLEDCPLLDE 77

                          90
                  ....*....|....*
gi 80861401   223 GDHGECTGHTHVDIH 237
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 265-359 4.84e-28

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 106.26  E-value: 4.84e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401   265 GCPREIPVDSPELKEALGHSIAQLNAQhNHIFYFKIDTVKKATSQVVAGVIYVIEFIARETNCSKQSKteLTADCETKHL 344
Cdd:pfam00031   1 GGLSPIPDNSPELQEALDFALAEYNAK-TDNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSKSKK--LLEDCPLLDE 77

                          90
                  ....*....|....*
gi 80861401   345 GQSLNCNANVYMRPW 359
Cdd:pfam00031  78 KWLGLCSAQVYKVPW 92
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 143-247 2.85e-26

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 101.78  E-value: 2.85e-26
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401 143 GCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHlFALREVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPSLREDCVPLPY 222
Cdd:cd00042   1 GGPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 80861401 223 GDHGECTGHTHVDIH-NTIAGFSQSC 247
Cdd:cd00042  80 GKKKFCTAKVWEKPWeNFKELLSFKC 105
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 21-125 1.42e-18

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 80.55  E-value: 1.42e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401     21 EGAQELNCNDETVFQAVDTALKKYNAELESGNQFVLYRVTKGTKKDGAETLYSFKYQIKEGNCSVQSGLtWQDCDFKDAE 100
Cdd:smart00043   4 GGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETNCKKLSVD-LENCPFLDQG 82

                           90       100
                   ....*....|....*....|....*..
gi 80861401    101 EaatGECTTTLGKK--ENKFSVATQIC 125
Cdd:smart00043  83 E---KFCTAKVWEKpwENKIKLVEFKC 106
Cystatin pfam00031
Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. ...
 22-114 1.01e-16

Cystatin domain; Very diverse family. Attempts to define separate sub-families failed. Typically, either the N-terminal or C-terminal end is very divergent. But splitting into two domains would make very short families. pfam00666 is related to this family but has not been included.


Pssm-ID: 425431  Cd Length: 92  Bit Score: 75.06  E-value: 1.01e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401    22 GAQELNCNDETVFQAVDTALKKYNAElESGNQFVLYRVTKGTKKDGAETLYSFKYQIKEGNCSVqSGLTWQDCDFKDaeE 101
Cdd:pfam00031   2 GLSPIPDNSPELQEALDFALAEYNAK-TDNYYFELVEVKRAKSQVVAGTNYFIKVEVGETDCSK-SKKLLEDCPLLD--E 77

                          90
                  ....*....|...
gi 80861401   102 AATGECTTTLGKK 114
Cdd:pfam00031  78 KWLGLCSAQVYKV 90
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 22-125 3.72e-07

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 48.24  E-value: 3.72e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 80861401  22 GAQELNCNDETVFQAVDTALKKYNAELESGNqFVLYRVTKGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQdCDFKDAEE 101
Cdd:cd00042   2 GPSDIPANDPEVQELADFAVAEYNKKSNDKY-LEFFKVLSAKSQVVAGTNYYITVEAGDTNCKKSSVPLDC-PDCKLLEE 79

                        90       100
                ....*....|....*....|....*.
gi 80861401 102 AATGECTTTLGKK--ENKFSVATQIC 125
Cdd:cd00042  80 GKKKFCTAKVWEKpwENFKELLSFKC 105
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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