transmembrane protein 144 [Homo sapiens]
L-rhamnose-proton symporter family protein; DMT family transporter( domain architecture ID 10545222)
L-rhamnose-proton symporter family protein such as Escherichia coli RhaT, which is involved in uptake of L-rhamnose across the cytoplasmic membrane with the concomitant transport of protons into the cell| DMT (drug/metabolite transporter) family transporter is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others
List of domain hits
Name | Accession | Description | Interval | E-value | ||||||
TMEM144 | pfam07857 | Transmembrane family, TMEM144 of transporters; Members of this family fall in to the drug ... |
9-344 | 1.81e-176 | ||||||
Transmembrane family, TMEM144 of transporters; Members of this family fall in to the drug/metabolite transporter (dmt) superfamily. They carry 10xTM domains arranged as 5+5. Although these two sets may originally have arisen by gene-duplication the divergence now is such that the two halves are no longer homologous. : Pssm-ID: 285141 Cd Length: 333 Bit Score: 492.33 E-value: 1.81e-176
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Name | Accession | Description | Interval | E-value | ||||||
TMEM144 | pfam07857 | Transmembrane family, TMEM144 of transporters; Members of this family fall in to the drug ... |
9-344 | 1.81e-176 | ||||||
Transmembrane family, TMEM144 of transporters; Members of this family fall in to the drug/metabolite transporter (dmt) superfamily. They carry 10xTM domains arranged as 5+5. Although these two sets may originally have arisen by gene-duplication the divergence now is such that the two halves are no longer homologous. Pssm-ID: 285141 Cd Length: 333 Bit Score: 492.33 E-value: 1.81e-176
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GRP | cd23110 | glucose/ribose porter family; The glucose/ribose porter (GRP) family (TC 2.A.7.5) includes two ... |
238-344 | 2.74e-07 | ||||||
glucose/ribose porter family; The glucose/ribose porter (GRP) family (TC 2.A.7.5) includes two functionally characterized members, a glucose uptake permease from Staphylococcus xylosus, and a probable ribose uptake permease from Lactobacillus sakei. Both proteins probably function by H(+) symport. This family also includes several putative and hypothetical membrane proteins that are probably involved in sugar transport across bacterial membranes. GRP family proteins have a distinctive topology: 10 putative transmembrane (TM) alpha-helical spanning domains per polypeptide chain, which apparently arose by intragenic duplication of an element encoding a primordial five-TM polypeptide. In Lactococcus lactis, GlcU was identified as the sole non-PTS (phosphoenolpyruvate:phosphotransferase systems) permease involved in the transport of glucose, which is driven by the proton-motive force. A gene from Bacillus subtilis, ycxE, that is homologous to glcU, could substitute for glcU in Escherichia coli glucose growth experiments and restored glucose repression in Staphylococcus xylosus glcU mutants. RbsU is encoded on the rbsUDK gene cluster, which encodes proteins involved in ribose uptake and phosphorylation. RbsR has been annotated as the repressor of the rbsUDK operon, based on its homology with RbsR repressors. The GRP family belongs to the Drug/Metabolite Transporter (DMT) superfamily (TC 2.A.7). Pssm-ID: 438513 [Multi-domain] Cd Length: 279 Bit Score: 51.30 E-value: 2.74e-07
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GlcU | COG4975 | Glucose uptake protein GlcU [Carbohydrate transport and metabolism]; |
247-344 | 2.93e-07 | ||||||
Glucose uptake protein GlcU [Carbohydrate transport and metabolism]; Pssm-ID: 444000 [Multi-domain] Cd Length: 288 Bit Score: 51.01 E-value: 2.93e-07
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Name | Accession | Description | Interval | E-value | ||||||
TMEM144 | pfam07857 | Transmembrane family, TMEM144 of transporters; Members of this family fall in to the drug ... |
9-344 | 1.81e-176 | ||||||
Transmembrane family, TMEM144 of transporters; Members of this family fall in to the drug/metabolite transporter (dmt) superfamily. They carry 10xTM domains arranged as 5+5. Although these two sets may originally have arisen by gene-duplication the divergence now is such that the two halves are no longer homologous. Pssm-ID: 285141 Cd Length: 333 Bit Score: 492.33 E-value: 1.81e-176
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GRP | cd23110 | glucose/ribose porter family; The glucose/ribose porter (GRP) family (TC 2.A.7.5) includes two ... |
238-344 | 2.74e-07 | ||||||
glucose/ribose porter family; The glucose/ribose porter (GRP) family (TC 2.A.7.5) includes two functionally characterized members, a glucose uptake permease from Staphylococcus xylosus, and a probable ribose uptake permease from Lactobacillus sakei. Both proteins probably function by H(+) symport. This family also includes several putative and hypothetical membrane proteins that are probably involved in sugar transport across bacterial membranes. GRP family proteins have a distinctive topology: 10 putative transmembrane (TM) alpha-helical spanning domains per polypeptide chain, which apparently arose by intragenic duplication of an element encoding a primordial five-TM polypeptide. In Lactococcus lactis, GlcU was identified as the sole non-PTS (phosphoenolpyruvate:phosphotransferase systems) permease involved in the transport of glucose, which is driven by the proton-motive force. A gene from Bacillus subtilis, ycxE, that is homologous to glcU, could substitute for glcU in Escherichia coli glucose growth experiments and restored glucose repression in Staphylococcus xylosus glcU mutants. RbsU is encoded on the rbsUDK gene cluster, which encodes proteins involved in ribose uptake and phosphorylation. RbsR has been annotated as the repressor of the rbsUDK operon, based on its homology with RbsR repressors. The GRP family belongs to the Drug/Metabolite Transporter (DMT) superfamily (TC 2.A.7). Pssm-ID: 438513 [Multi-domain] Cd Length: 279 Bit Score: 51.30 E-value: 2.74e-07
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GlcU | COG4975 | Glucose uptake protein GlcU [Carbohydrate transport and metabolism]; |
247-344 | 2.93e-07 | ||||||
Glucose uptake protein GlcU [Carbohydrate transport and metabolism]; Pssm-ID: 444000 [Multi-domain] Cd Length: 288 Bit Score: 51.01 E-value: 2.93e-07
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GRP | cd23110 | glucose/ribose porter family; The glucose/ribose porter (GRP) family (TC 2.A.7.5) includes two ... |
16-340 | 1.41e-06 | ||||||
glucose/ribose porter family; The glucose/ribose porter (GRP) family (TC 2.A.7.5) includes two functionally characterized members, a glucose uptake permease from Staphylococcus xylosus, and a probable ribose uptake permease from Lactobacillus sakei. Both proteins probably function by H(+) symport. This family also includes several putative and hypothetical membrane proteins that are probably involved in sugar transport across bacterial membranes. GRP family proteins have a distinctive topology: 10 putative transmembrane (TM) alpha-helical spanning domains per polypeptide chain, which apparently arose by intragenic duplication of an element encoding a primordial five-TM polypeptide. In Lactococcus lactis, GlcU was identified as the sole non-PTS (phosphoenolpyruvate:phosphotransferase systems) permease involved in the transport of glucose, which is driven by the proton-motive force. A gene from Bacillus subtilis, ycxE, that is homologous to glcU, could substitute for glcU in Escherichia coli glucose growth experiments and restored glucose repression in Staphylococcus xylosus glcU mutants. RbsU is encoded on the rbsUDK gene cluster, which encodes proteins involved in ribose uptake and phosphorylation. RbsR has been annotated as the repressor of the rbsUDK operon, based on its homology with RbsR repressors. The GRP family belongs to the Drug/Metabolite Transporter (DMT) superfamily (TC 2.A.7). Pssm-ID: 438513 [Multi-domain] Cd Length: 279 Bit Score: 48.99 E-value: 1.41e-06
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Sugar_transport | pfam06800 | Sugar transport protein; This is a family of bacterial sugar transporters approximately 300 ... |
268-344 | 1.55e-03 | ||||||
Sugar transport protein; This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs, Pssm-ID: 429127 [Multi-domain] Cd Length: 280 Bit Score: 39.56 E-value: 1.55e-03
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Blast search parameters | ||||
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