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Conserved domains on  [gi|126722682|ref|NP_083420|]
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DnaJ domain-containing protein isoform 3 [Mus musculus]

Protein Classification

J domain-containing protein( domain architecture ID 10446266)

J domain-containing protein containing a similar domain as DnaJ, a protein that plays crucial roles in protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of Hsp70.

CATH:  1.10.287.110
Gene Ontology:  GO:0006457
PubMed:  35729039|9644977|8016869|15170475
SCOP:  4000605

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-66 1.58e-33

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


:

Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 115.26  E-value: 1.58e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126722682    3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYD 66
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPE-AEEKFKEINEAYEVLSDPEKRAIYD 63
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-66 1.58e-33

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 115.26  E-value: 1.58e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126722682    3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYD 66
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPE-AEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 3-69 6.73e-32

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 113.64  E-value: 6.73e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDRSR 69
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPE-AEEKFKEINEAYEVLSDPEKRAAYDRFG 66
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 3-67 3.40e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 112.16  E-value: 3.40e-29
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK10767   5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKE-AEEKFKEIKEAYEVLSDPQKRAAYDQ 68
DnaJ smart00271
DnaJ molecular chaperone homology domain;
2-61 1.46e-28

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 102.31  E-value: 1.46e-28
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722682     2 VNYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEAAEEKFKQVAEAYHILSDAKK 61
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 4-67 1.02e-26

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 105.38  E-value: 1.02e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126722682    4 YYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPgDKEAaEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:TIGR02349   2 YYEILGVSKDASEEEIKKAYRKLAKKYHPDRNK-DKEA-EEKFKEINEAYEVLSDPEKRAQYDQ 63
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 3-58 1.35e-25

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 94.53  E-value: 1.35e-25
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDkEAAEEKFKQVAEAYHILSD 58
Cdd:cd06257    1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD-PEAEEKFKEINEAYEVLSD 55
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-67 9.99e-20

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 86.80  E-value: 9.99e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgDKEAAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:NF037946   6 DYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRN--KAPDAAEIFAEINEAYEVLSNPEKRANYDK 68
 
Name Accession Description Interval E-value
DnaJ pfam00226
DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is ...
 3-66 1.58e-33

DnaJ domain; DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.


Pssm-ID: 395170 [Multi-domain]  Cd Length: 63  Bit Score: 115.26  E-value: 1.58e-33
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126722682    3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYD 66
Cdd:pfam00226   1 DYYEILGVSPDASDEEIKKAYRKLALKYHPDKNPGDPE-AEEKFKEINEAYEVLSDPEKRAIYD 63
DnaJ COG0484
DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational ...
 3-69 6.73e-32

DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440252 [Multi-domain]  Cd Length: 139  Bit Score: 113.64  E-value: 6.73e-32
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDRSR 69
Cdd:COG0484    1 DYYEILGVSRDASAEEIKKAYRKLAKKYHPDRNPGDPE-AEEKFKEINEAYEVLSDPEKRAAYDRFG 66
PRK10767 PRK10767
chaperone protein DnaJ; Provisional
 3-67 3.40e-29

chaperone protein DnaJ; Provisional


Pssm-ID: 236757 [Multi-domain]  Cd Length: 371  Bit Score: 112.16  E-value: 3.40e-29
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK10767   5 DYYEVLGVSRNASEDEIKKAYRKLAMKYHPDRNPGDKE-AEEKFKEIKEAYEVLSDPQKRAAYDQ 68
DnaJ smart00271
DnaJ molecular chaperone homology domain;
2-61 1.46e-28

DnaJ molecular chaperone homology domain;


Pssm-ID: 197617 [Multi-domain]  Cd Length: 60  Bit Score: 102.31  E-value: 1.46e-28
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722682     2 VNYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEAAEEKFKQVAEAYHILSDAKK 61
Cdd:smart00271   1 TDYYEILGVPRDASLDEIKKAYRKLALKYHPDKNPGDKEEAEEKFKEINEAYEVLSDPEK 60
DnaJ_bact TIGR02349
chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the ...
 4-67 1.02e-26

chaperone protein DnaJ; This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.


Pssm-ID: 274090 [Multi-domain]  Cd Length: 354  Bit Score: 105.38  E-value: 1.02e-26
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126722682    4 YYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPgDKEAaEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:TIGR02349   2 YYEILGVSKDASEEEIKKAYRKLAKKYHPDRNK-DKEA-EEKFKEINEAYEVLSDPEKRAQYDQ 63
DnaJ cd06257
DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and ...
 3-58 1.35e-25

DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, an important chaperonine family. Hsp40 proteins are characterized by the presence of a J domain, which mediates the interaction with Hsp70. They may contain other domains as well, and the architectures provide a means of classification.


Pssm-ID: 99751 [Multi-domain]  Cd Length: 55  Bit Score: 94.53  E-value: 1.35e-25
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDkEAAEEKFKQVAEAYHILSD 58
Cdd:cd06257    1 DYYDILGVPPDASDEEIKKAYRKLALKYHPDKNPDD-PEAEEKFKEINEAYEVLSD 55
SEC63 COG5407
Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular ...
 3-63 1.40e-25

Preprotein translocase subunit Sec63 [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 444165 [Multi-domain]  Cd Length: 61  Bit Score: 94.68  E-value: 1.40e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKeAAEEKFKQVAEAYHILSDAKKRK 63
Cdd:COG5407    1 DPYEVLGVAKTASADEIKKAYRKLAKKYHPDRNKGDP-KAEERFKEINEAYELLSDAEKRA 60
PRK14279 PRK14279
molecular chaperone DnaJ;
3-85 4.71e-25

molecular chaperone DnaJ;


Pssm-ID: 237655 [Multi-domain]  Cd Length: 392  Bit Score: 101.35  E-value: 4.71e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKeAAEEKFKQVAEAYHILSDAKKRKDYDRSRWNRNKGEIRGDGH 82
Cdd:PRK14279  10 DFYKELGVSSDASAEEIKKAYRKLARELHPDANPGDP-AAEERFKAVSEAHDVLSDPAKRKEYDETRRLFAGGGFGGRRF 88


                 ...
gi 126722682  83 DKG 85
Cdd:PRK14279  89 DGG 91
PRK14277 PRK14277
chaperone protein DnaJ; Provisional
 3-67 6.00e-25

chaperone protein DnaJ; Provisional


Pssm-ID: 184599 [Multi-domain]  Cd Length: 386  Bit Score: 101.03  E-value: 6.00e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14277   6 DYYEILGVDRNATEEEIKKAYRRLAKKYHPDLNPGDKE-AEQKFKEINEAYEILSDPQKRAQYDQ 69
PRK14295 PRK14295
molecular chaperone DnaJ;
3-69 1.49e-24

molecular chaperone DnaJ;


Pssm-ID: 237665 [Multi-domain]  Cd Length: 389  Bit Score: 99.92  E-value: 1.49e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKeAAEEKFKQVAEAYHILSDAKKRKDYDRSR 69
Cdd:PRK14295  10 DYYKVLGVPKDATEAEIKKAYRKLAREYHPDANKGDA-KAEERFKEISEAYDVLSDEKKRKEYDEAR 75
PRK14294 PRK14294
chaperone protein DnaJ; Provisional
 4-67 1.69e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 237664 [Multi-domain]  Cd Length: 366  Bit Score: 99.45  E-value: 1.69e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126722682   4 YYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14294   6 YYEILGVTRDASEEEIKKSYRKLAMKYHPDRNPGDKE-AEELFKEAAEAYEVLSDPKKRGIYDQ 68
PRK14301 PRK14301
chaperone protein DnaJ; Provisional
 3-67 3.18e-24

chaperone protein DnaJ; Provisional


Pssm-ID: 237668 [Multi-domain]  Cd Length: 373  Bit Score: 99.05  E-value: 3.18e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14301   5 DYYEVLGVSRDASEDEIKKAYRKLALQYHPDRNPDNPE-AEQKFKEAAEAYEVLRDAEKRARYDR 68
PRK14289 PRK14289
molecular chaperone DnaJ;
3-67 5.47e-24

molecular chaperone DnaJ;


Pssm-ID: 237660 [Multi-domain]  Cd Length: 386  Bit Score: 98.36  E-value: 5.47e-24
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14289   6 DYYEVLGVSKTATVDEIKKAYRKKAIQYHPDKNPGDKE-AEEKFKEAAEAYDVLSDPDKRSRYDQ 69
CbpA COG2214
Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];
1-77 7.94e-24

Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription];


Pssm-ID: 441816 [Multi-domain]  Cd Length: 91  Bit Score: 91.32  E-value: 7.94e-24
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 126722682   1 MVNYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEAAEEKFKQVAEAYHILSDAKKRKDYDRSRWNRNKGEI 77
Cdd:COG2214    4 LKDHYAVLGVPPDASLEEIRQAYRRLAKLLHPDRGGELKALAEELFQRLNEAYEVLSDPERRAEYDRELGQSGKGSA 80
PRK14290 PRK14290
chaperone protein DnaJ; Provisional
 3-68 1.74e-23

chaperone protein DnaJ; Provisional


Pssm-ID: 172778 [Multi-domain]  Cd Length: 365  Bit Score: 96.92  E-value: 1.74e-23
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEAAEEKFKQVAEAYHILSDAKKRKDYDRS 68
Cdd:PRK14290   4 DYYKILGVDRNASQEDIKKAFRELAKKWHPDLHPGNKAEAEEKFKEISEAYEVLSDPQKRRQYDQT 69
PRK14297 PRK14297
molecular chaperone DnaJ;
3-67 1.24e-22

molecular chaperone DnaJ;


Pssm-ID: 184611 [Multi-domain]  Cd Length: 380  Bit Score: 94.46  E-value: 1.24e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14297   5 DYYEVLGLEKGASDDEIKKAFRKLAIKYHPDKNKGNKE-AEEKFKEINEAYQVLSDPQKKAQYDQ 68
PRK14284 PRK14284
chaperone protein DnaJ; Provisional
 3-67 1.30e-22

chaperone protein DnaJ; Provisional


Pssm-ID: 237658 [Multi-domain]  Cd Length: 391  Bit Score: 94.52  E-value: 1.30e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14284   2 DYYTILGVSKTASPEEIKKAYRKLAVKYHPDKNPGDAE-AEKRFKEVSEAYEVLSDAQKRESYDR 65
PRK14281 PRK14281
chaperone protein DnaJ; Provisional
 3-67 1.77e-22

chaperone protein DnaJ; Provisional


Pssm-ID: 237657 [Multi-domain]  Cd Length: 397  Bit Score: 94.49  E-value: 1.77e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14281   4 DYYEVLGVSRSADKDEIKKAYRKLALKYHPDKNPDNKE-AEEHFKEVNEAYEVLSNDDKRRRYDQ 67
PRK14298 PRK14298
chaperone protein DnaJ; Provisional
 3-67 2.23e-22

chaperone protein DnaJ; Provisional


Pssm-ID: 184612 [Multi-domain]  Cd Length: 377  Bit Score: 93.76  E-value: 2.23e-22
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgdKEA-AEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14298   6 DYYEILGLSKDASVEDIKKAYRKLAMKYHPDKN---KEPdAEEKFKEISEAYAVLSDAEKRAQYDR 68
PRK14282 PRK14282
chaperone protein DnaJ; Provisional
 3-67 1.87e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 184603 [Multi-domain]  Cd Length: 369  Bit Score: 91.39  E-value: 1.87e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEAAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14282   5 DYYEILGVSRNATQEEIKRAYKRLVKEWHPDRHPENRKEAEQKFKEIQEAYEVLSDPQKRAMYDR 69
PRK14291 PRK14291
chaperone protein DnaJ; Provisional
 3-122 6.21e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 237661 [Multi-domain]  Cd Length: 382  Bit Score: 89.83  E-value: 6.21e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPgDKEaAEEKFKQVAEAYHILSDAKKRKDYDR----------SRWNR 72
Cdd:PRK14291   4 DYYEILGVSRNATQEEIKKAYRRLARKYHPDFNK-NPE-AEEKFKEINEAYQVLSDPEKRKLYDQfghaafsgsgQQQQG 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 126722682  73 NKGEIRGDGHDKGETIR-VNDSRDETD-WEEKICSRRPRHTFQKVTEDEDLF 122
Cdd:PRK14291  82 QEGFSDFGGGNIEDILEdVFDIFGFGDiFGRRRATRERRKTYQRPVKGEDIY 133
PRK14299 PRK14299
chaperone protein DnaJ; Provisional
 3-67 7.35e-21

chaperone protein DnaJ; Provisional


Pssm-ID: 237667 [Multi-domain]  Cd Length: 291  Bit Score: 88.46  E-value: 7.35e-21
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPD--KNPGdkeaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14299   5 DYYAILGVPKNASQDEIKKAFKKLARKYHPDvnKSPG----AEEKFKEINEAYTVLSDPEKRRIYDT 67
PRK14292 PRK14292
chaperone protein DnaJ; Provisional
 1-80 2.72e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 237662 [Multi-domain]  Cd Length: 371  Bit Score: 88.02  E-value: 2.72e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722682   1 MVNYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPgdKEAAEEKFKQVAEAYHILSDAKKRKDYDRSRWNRNKGEIRGD 80
Cdd:PRK14292   1 MMDYYELLGVSRTASADEIKSAYRKLALKYHPDRNK--EKGAAEKFAQINEAYAVLSDAEKRAHYDRFGTAPGAGMPGGD 78
PRK14286 PRK14286
chaperone protein DnaJ; Provisional
 4-67 4.98e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 172774 [Multi-domain]  Cd Length: 372  Bit Score: 87.35  E-value: 4.98e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126722682   4 YYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14286   6 YYDILGVSKSANDEEIKSAYRKLAIKYHPDKNKGNKE-SEEKFKEATEAYEILRDPKKRQAYDQ 68
PRK14276 PRK14276
chaperone protein DnaJ; Provisional
 4-66 7.21e-20

chaperone protein DnaJ; Provisional


Pssm-ID: 237653 [Multi-domain]  Cd Length: 380  Bit Score: 87.07  E-value: 7.21e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   4 YYKVLGVPRNASSSDIKRAFHQLALQVHPDKN--PGdkeaAEEKFKQVAEAYHILSDAKKRKDYD 66
Cdd:PRK14276   6 YYDRLGVSKDASQDEIKKAYRKLSKKYHPDINkePG----AEEKYKEVQEAYETLSDPQKRAAYD 66
terminal_TopJ NF037946
terminal organelle assembly protein TopJ;
3-67 9.99e-20

terminal organelle assembly protein TopJ;


Pssm-ID: 468284 [Multi-domain]  Cd Length: 440  Bit Score: 86.80  E-value: 9.99e-20
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgDKEAAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:NF037946   6 DYYEVLGVDRDADDQEIKKAFRKLAKKYHPDRN--KAPDAAEIFAEINEAYEVLSNPEKRANYDK 68
PRK14283 PRK14283
chaperone protein DnaJ; Provisional
 3-67 1.06e-19

chaperone protein DnaJ; Provisional


Pssm-ID: 184604 [Multi-domain]  Cd Length: 378  Bit Score: 86.42  E-value: 1.06e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgDKEAAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14283   6 DYYEVLGVDRNADKKEIKKAYRKLARKYHPDVS--EEEGAEEKFKEISEAYAVLSDDEKRQRYDQ 68
PRK14293 PRK14293
molecular chaperone DnaJ;
1-67 3.89e-19

molecular chaperone DnaJ;


Pssm-ID: 237663 [Multi-domain]  Cd Length: 374  Bit Score: 84.66  E-value: 3.89e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 126722682   1 MVNYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgdKEA-AEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14293   2 AADYYEILGVSRDADKDELKRAYRRLARKYHPDVN---KEPgAEDRFKEINRAYEVLSDPETRARYDQ 66
PRK14278 PRK14278
chaperone protein DnaJ; Provisional
 3-66 4.40e-19

chaperone protein DnaJ; Provisional


Pssm-ID: 237654 [Multi-domain]  Cd Length: 378  Bit Score: 84.72  E-value: 4.40e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGdkEAAEEKFKQVAEAYHILSDAKKRKDYD 66
Cdd:PRK14278   4 DYYGLLGVSRNASDAEIKRAYRKLARELHPDVNPD--EEAQEKFKEISVAYEVLSDPEKRRIVD 65
PRK14280 PRK14280
molecular chaperone DnaJ;
3-67 4.94e-19

molecular chaperone DnaJ;


Pssm-ID: 237656 [Multi-domain]  Cd Length: 376  Bit Score: 84.39  E-value: 4.94e-19
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgdKEA-AEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14280   5 DYYEVLGVSKSASKDEIKKAYRKLSKKYHPDIN---KEEgADEKFKEISEAYEVLSDDQKRAQYDQ 67
PRK14300 PRK14300
chaperone protein DnaJ; Provisional
 3-115 5.43e-16

chaperone protein DnaJ; Provisional


Pssm-ID: 172788 [Multi-domain]  Cd Length: 372  Bit Score: 75.82  E-value: 5.43e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgDKEAAEEKFKQVAEAYHILSDAKKRKDYDRSRWN--RNKGEIRGD 80
Cdd:PRK14300   4 DYYQILGVSKTASQADLKKAYLKLAKQYHPDTT--DAKDAEKKFKEINAAYDVLKDEQKRAAYDRFGHDafQNQQSRGGG 81

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 126722682  81 GHDKGETIRVNDSRDETDWEEKICSRRPRHTFQKV 115
Cdd:PRK14300  82 GNHGGFHPDINDIFGDFFSDFMGGSRRSRPTSSKV 116
PRK14285 PRK14285
chaperone protein DnaJ; Provisional
 3-67 1.12e-15

chaperone protein DnaJ; Provisional


Pssm-ID: 172773 [Multi-domain]  Cd Length: 365  Bit Score: 75.03  E-value: 1.12e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14285   4 DYYEILGLSKGASKDEIKKAYRKIAIKYHPDKNKGNKE-AESIFKEATEAYEVLIDDNKRAQYDR 67
DjlA COG1076
DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];
1-63 1.27e-15

DnaJ domain-containing protein [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440694 [Multi-domain]  Cd Length: 75  Bit Score: 69.06  E-value: 1.27e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 126722682   1 MVNYYKVLGVPRNASSSDIKRAFHQLALQVHPDK-----NPGDKEAAEEKFKQVAEAYHILSDAKKRK 63
Cdd:COG1076    3 LDDAFELLGLPPDADDAELKRAYRKLQREHHPDRlaaglPEEEQRLALQKAAAINEAYETLKDPRGID 70
PRK14288 PRK14288
molecular chaperone DnaJ;
2-67 6.73e-15

molecular chaperone DnaJ;


Pssm-ID: 172776 [Multi-domain]  Cd Length: 369  Bit Score: 72.80  E-value: 6.73e-15
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 126722682   2 VNYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKEaAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14288   3 LSYYEILEVEKHSNQETIKKSYRKLALKYHPDRNAGDKE-AEEKFKLINEAYGVLSDEKKRALYDR 67
PTZ00037 PTZ00037
DnaJ_C chaperone protein; Provisional
 4-66 1.69e-14

DnaJ_C chaperone protein; Provisional


Pssm-ID: 240236 [Multi-domain]  Cd Length: 421  Bit Score: 71.78  E-value: 1.69e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 126722682   4 YYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpGDkeaaEEKFKQVAEAYHILSDAKKRKDYD 66
Cdd:PTZ00037  30 LYEVLNLSKDCTTSEIKKAYRKLAIKHHPDKG-GD----PEKFKEISRAYEVLSDPEKRKIYD 87
PRK10266 PRK10266
curved DNA-binding protein;
3-114 2.29e-14

curved DNA-binding protein;


Pssm-ID: 182347 [Multi-domain]  Cd Length: 306  Bit Score: 70.62  E-value: 2.29e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgdKEA-AEEKFKQVAEAYHILSDAKKRKDYDRSRWNRNKGEI-RGD 80
Cdd:PRK10266   5 DYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVS---KEPdAEARFKEVAEAWEVLSDEQRRAEYDQLWQHRNDPQFnRQF 81

                         90       100       110
                 ....*....|....*....|....*....|....
gi 126722682  81 GHDKGETirvNDSRDETDWEEKICSRRPRHTFQK 114
Cdd:PRK10266  82 QHGDGQS---FNAEDFDDIFSSIFGQHARQSRQR 112
PRK14287 PRK14287
chaperone protein DnaJ; Provisional
 3-67 3.61e-14

chaperone protein DnaJ; Provisional


Pssm-ID: 237659 [Multi-domain]  Cd Length: 371  Bit Score: 70.81  E-value: 3.61e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgDKEAAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14287   5 DYYEVLGVDRNASVDEVKKAYRKLARKYHPDVN--KAPDAEDKFKEVKEAYDTLSDPQKKAHYDQ 67
PRK14296 PRK14296
chaperone protein DnaJ; Provisional
 3-67 7.96e-13

chaperone protein DnaJ; Provisional


Pssm-ID: 237666 [Multi-domain]  Cd Length: 372  Bit Score: 66.89  E-value: 7.96e-13
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   3 NYYKVLGVPRNASSSDIKRAFHQLALQVHPDKNpgDKEAAEEKFKQVAEAYHILSDAKKRKDYDR 67
Cdd:PRK14296   5 DYYEVLGVSKTASEQEIRQAYRKLAKQYHPDLN--KSPDAHDKMVEINEAADVLLDKDKRKQYDQ 67
PTZ00341 PTZ00341
Ring-infected erythrocyte surface antigen; Provisional
 4-75 5.88e-09

Ring-infected erythrocyte surface antigen; Provisional


Pssm-ID: 173534 [Multi-domain]  Cd Length: 1136  Bit Score: 55.95  E-value: 5.88e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 126722682    4 YYKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDKeaAEEKFKQVAEAYHILSDAKKRKDYDRSRWNRNKG 75
Cdd:PTZ00341  575 FYDILGVGVNADMKEISERYFKLAENYYPPKRSGNE--GFHKFKKINEAYQILGDIDKKKMYNKFGYDGIKG 644
djlA PRK09430
co-chaperone DjlA;
5-63 2.94e-05

co-chaperone DjlA;


Pssm-ID: 236512 [Multi-domain]  Cd Length: 267  Bit Score: 44.03  E-value: 2.94e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 126722682   5 YKVLGVPRNASSSDIKRAFHQLALQVHPDKNPGDK------EAAEEKFKQVAEAYHILSDAKKRK 63
Cdd:PRK09430 203 YKVLGVSESDDDQEIKRAYRKLMSEHHPDKLVAKGlppemmEMAKEKAQEIQAAYELIKKQKGFK 267
ZUO1 COG5269
Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / ...
 2-66 2.75e-03

Ribosome-associated chaperone zuotin [Translation, ribosomal structure and biogenesis / Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 227594 [Multi-domain]  Cd Length: 379  Bit Score: 38.48  E-value: 2.75e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 126722682   2 VNYYKVLGVPR---NASSSDIKRAFHQLALQVHPDKNP-GDKEAAEEKFKQVAEAYHILSDAKKRKDYD 66
Cdd:COG5269   43 VDLYALLGLSKyrtKAIPPQILKAHKKKVYKYHPDKTAaGGNKGCDEFFKLIQKAREVLGDRKLRLQYD 111
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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