|
Name |
Accession |
Description |
Interval |
E-value |
| RarA |
COG2256 |
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ... |
220-656 |
0e+00 |
|
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];
Pssm-ID: 441857 [Multi-domain] Cd Length: 439 Bit Score: 610.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 220 KPLADKMRPDTLQDYIGQSRAVGQETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIANNSKKHsirFVTLSATNAKTND 299
Cdd:COG2256 13 APLAERMRPRTLDEVVGQEHLLGPGKPLRRAIEAGRLSSMILWGPPGTGKTTLARLIANATDAE---FVALSAVTSGVKD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 300 VRDVIKQAQNEKSFfKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEA 379
Cdd:COG2256 90 IREVIEEARERRAY-GRRTILFVDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNSALLSRCRVFVLKPLSEED 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 380 MVTILMRAinslgihvldssrptdpLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLArlssrkvfckk 459
Cdd:COG2256 169 LEQLLERA-----------------LADDERGLGGYKLELDDEALEALARLADGDARRALNALELAVLS----------- 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 460 sgqTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFAS 539
Cdd:COG2256 221 ---APPDGVIEITLELVEEALQRRALRYDKDGDEHYDLISAFIKSIRGSDPDAALYWLARMLEAGEDPRFIARRLVIMAS 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 540 EDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRshQGPLPPVPLHLRNAPTR 619
Cdd:COG2256 298 EDIGLADPQALQIAVAAAQAVERLGMPEGRIALAQAVIYLATAPKSNAAYLAINAALADVR--EGGSLPVPLHLRNAPTK 375
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 254540120 620 LMKDLGYGKGYKYnpMYSEP---VDQDYLPEELRGVDFFK 656
Cdd:COG2256 376 LMKELGYGKGYKY--PHDYPggyVGQQYLPDELKGRRYYE 413
|
|
| PRK13342 |
PRK13342 |
recombination factor protein RarA; Reviewed |
221-656 |
0e+00 |
|
recombination factor protein RarA; Reviewed
Pssm-ID: 237355 [Multi-domain] Cd Length: 413 Bit Score: 601.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 221 PLADKMRPDTLQDYIGQSRAVGQETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIANNSKKHsirFVTLSATNAKTNDV 300
Cdd:PRK13342 1 PLAERMRPKTLDEVVGQEHLLGPGKPLRRMIEAGRLSSMILWGPPGTGKTTLARIIAGATDAP---FEALSAVTSGVKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 301 RDVIKQAQNEKSFfKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAM 380
Cdd:PRK13342 78 REVIEEARQRRSA-GRRTILFIDEIHRFNKAQQDALLPHVEDGTITLIGATTENPSFEVNPALLSRAQVFELKPLSEEDI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 381 VTILMRAINslgihvlDSSRPTDPlshssncssepsvfIEDKAVDTLAYLSDGDARTGLNGLQLAVLarlssrkvfckks 460
Cdd:PRK13342 157 EQLLKRALE-------DKERGLVE--------------LDDEALDALARLANGDARRALNLLELAAL------------- 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 461 gqtyspSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASE 540
Cdd:PRK13342 203 ------GVDSITLELLEEALQKRAARYDKDGDEHYDLISALHKSIRGSDPDAALYYLARMLEAGEDPLFIARRLVIIASE 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 541 DIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRshQGPLPPVPLHLRNAPTRL 620
Cdd:PRK13342 277 DIGLADPNALQVAVAAADAVERIGMPEGRIALAQAVIYLALAPKSNAAYTAINAALADVR--EGGSLPVPLHLRNAPTKL 354
|
410 420 430
....*....|....*....|....*....|....*....
gi 254540120 621 MKDLGYGKGYKYnpMYSEP---VDQDYLPEELRGVDFFK 656
Cdd:PRK13342 355 MKELGYGKGYKY--PHDYPngyVGQQYLPDELKGKRYYE 391
|
|
| PRK13341 |
PRK13341 |
AAA family ATPase; |
220-655 |
2.00e-135 |
|
AAA family ATPase;
Pssm-ID: 237354 [Multi-domain] Cd Length: 725 Bit Score: 414.07 E-value: 2.00e-135
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 220 KPLADKMRPDTLQDYIGQSRAVGQETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIANNSKKHsirFVTLSATNAKTND 299
Cdd:PRK13341 16 APLADRLRPRTLEEFVGQDHILGEGRLLRRAIKADRVGSLILYGPPGVGKTTLARIIANHTRAH---FSSLNAVLAGVKD 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 300 VRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEA 379
Cdd:PRK13341 93 LRAEVDRAKERLERHGKRTILFIDEVHRFNKAQQDALLPWVENGTITLIGATTENPYFEVNKALVSRSRLFRLKSLSDED 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 380 MVTILMRAINslgihvlDSSRPTDPLShssncssepsVFIEDKAVDTLAYLSDGDARTGLNGLQLAVlarlssrkvfckk 459
Cdd:PRK13341 173 LHQLLKRALQ-------DKERGYGDRK----------VDLEPEAEKHLVDVANGDARSLLNALELAV------------- 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 460 sgQTYSP---SRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVR 536
Cdd:PRK13341 223 --ESTPPdedGLIDITLAIAEESIQQRAVLYDKEGDAHFDTISAFIKSLRGSDPDAALYWLARMVEAGEDPRFIFRRMLI 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 537 FASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSIEVYSAYNNVKAClrsHQGPLPPVPLHLRNa 616
Cdd:PRK13341 301 AASEDVGLADPQALVVVEACAAAFERVGLPEGLYPLAQAALYLATAPKSNSVLGFFDALKKV---REEQVQDVPNHLRD- 376
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 254540120 617 PTRLMKDLGYGKGYKYNPMYSEP-VDQDYLPEELRGVDFF 655
Cdd:PRK13341 377 ANRDGKAFGDGVGYRYPHAFRDHwVAQQYLPEALQGEVFW 416
|
|
| MgsA_C |
pfam12002 |
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA ... |
507-656 |
3.60e-80 |
|
MgsA AAA+ ATPase C terminal; The MgsA protein possesses DNA-dependent ATPase and ssDNA annealing activities. MgsA contributes to the recovery of stalled replication forks and therefore prevents genomic instability caused by aberrant DNA replication. Additionally, MgsA may play a role in chromosomal segregation. This is consistent with a report that MgsA co-localizes with the replisome and affects chromosome segregation. This domain represents the C terminal region of MgsA.
Pssm-ID: 463426 [Multi-domain] Cd Length: 158 Bit Score: 251.11 E-value: 3.60e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 507 GSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCVVYFARAPKSI 586
Cdd:pfam12002 1 GSDPDAALYWLARMLEAGEDPLFIARRLVIIASEDIGLADPQALVVAVAAAQAVERIGMPEARIPLAQAVIYLALAPKSN 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 254540120 587 EVYSAYNNVKACLRshQGPLPPVPLHLRNAPTRLMKDLGYGKGYKYNPMYSE-PVDQDYLPEELRGVDFFK 656
Cdd:pfam12002 81 SAYLAIDAALADVR--EGGSLPVPLHLRNAPTKLMKKLGYGKGYKYPHDYPNgYVKQQYLPDELKGRRYYE 149
|
|
| PRK14700 |
PRK14700 |
recombination factor protein RarA; Provisional |
337-650 |
1.52e-45 |
|
recombination factor protein RarA; Provisional
Pssm-ID: 173163 [Multi-domain] Cd Length: 300 Bit Score: 164.03 E-value: 1.52e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 337 LPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSlgihvldssrptdplshsSNCSSEPS 416
Cdd:PRK14700 1 MPYVESGKIILIGATTENPTYYLNDALVSRLFILRLKRLSLVATQKLIEKALSQ------------------DEVLAKHK 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 417 VFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKVFCKKSgqtyspsrvlITENDVKEGLQRSHilydRAGEEHYN 496
Cdd:PRK14700 63 FKIDDGLYNAMHNYNEGDCRKILNLLERMFLISTRGDEIYLNKE----------LFDQAVGETSRDFH----REGKEFYE 128
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 497 CISALHKAMRGSDQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMPECEVLLAQCV 576
Cdd:PRK14700 129 QLSAFHKSVRGTDPDAAIFWLSVMLDNGVDPLVIARRMLCIASEDIGNADPQALRVAMDAWNAYEKLGMPEGRLVLAQAA 208
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254540120 577 VYFARAPKSIEVYSAYNNVKACLRShQGPLpPVPLHLRNaptrlMKDLGYGKGYKYNPMYsepVDQDYLPEELR 650
Cdd:PRK14700 209 IYLAVAPKSNACYKALAQAQQLVKS-LGNI-DVPQHLKN-----YKDSNYLYPHNYPNSY---VIQQYLPDNII 272
|
|
| AAA_assoc_2 |
pfam16193 |
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA ... |
417-506 |
3.09e-28 |
|
AAA C-terminal domain; AAA_assoc_2 is found at the C-terminus of a relatively small set of AAA domains in proteins ranging from archaeal to fungi, plants and mammals.
Pssm-ID: 465057 Cd Length: 81 Bit Score: 107.94 E-value: 3.09e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 417 VFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRKVfckksgqtyspsrVLITENDVKEGLQRSHILYDRAGEEHYN 496
Cdd:pfam16193 5 IELDDEALEALAELADGDARRALNALELAVLSTPPDDGG-------------IHITLEILEEALQRKALRYDKDGDEHYD 71
|
90
....*....|
gi 254540120 497 CISALHKAMR 506
Cdd:pfam16193 72 LISAFHKSIR 81
|
|
| AAA |
cd00009 |
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ... |
235-371 |
1.17e-21 |
|
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.
Pssm-ID: 99707 [Multi-domain] Cd Length: 151 Bit Score: 91.82 E-value: 1.17e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 235 IGQSRAVGQetlLRSLLEANEIPSLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFF 314
Cdd:cd00009 1 VGQEEAIEA---LREALELPPPKNLLLYGPPGTGKTTLARAIANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLLF 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 315 KRK-----TILFIDEIHRFNKSQQDTFLP--------HVECGTITLIGATTENPSFQVNAALLSRCRVIV 371
Cdd:cd00009 78 ELAekakpGVLFIDEIDSLSRGAQNALLRvletlndlRIDRENVRVIGATNRPLLGDLDRALYDRLDIRI 147
|
|
| AAA |
pfam00004 |
ATPase family associated with various cellular activities (AAA); AAA family proteins often ... |
259-372 |
1.29e-19 |
|
ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.
Pssm-ID: 459627 [Multi-domain] Cd Length: 130 Bit Score: 85.34 E-value: 1.29e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSKkhsIRFVTLSATN-------AKTNDVRDVIKQAQNeksffKRKTILFIDEIHRFNKS 331
Cdd:pfam00004 1 LLLYGPPGTGKTTLAKAVAKELG---APFIEISGSElvskyvgESEKRLRELFEAAKK-----LAPCVIFIDEIDALAGS 72
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 254540120 332 Q-----------QDTFLPHVE-----CGTITLIGATTEnpSFQVNAALLSRCRVIVL 372
Cdd:pfam00004 73 RgsggdsesrrvVNQLLTELDgftssNSKVIVIAATNR--PDKLDPALLGRFDRIIE 127
|
|
| RuvB |
COG2255 |
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, ... |
227-393 |
2.60e-18 |
|
Holliday junction resolvasome RuvABC, ATP-dependent DNA helicase subunit RuvB [Replication, recombination and repair];
Pssm-ID: 441856 [Multi-domain] Cd Length: 337 Bit Score: 86.67 E-value: 2.60e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 227 RPDTLQDYIGQSRAVGQetlLRSLLEA----NE-IPSLILWGPPGCGKTTLAHIIANNSKKhSIRfVT----------LS 291
Cdd:COG2255 23 RPKRLDEYIGQEKVKEN---LKIFIEAakkrGEaLDHVLLYGPPGLGKTTLAHIIANEMGV-NIR-ITsgpaiekpgdLA 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 292 A--TNAKTNDVrdvikqaqneksffkrktiLFIDEIHRFNKSQQDTFLPHVECGTI--------------------TLIG 349
Cdd:COG2255 98 AilTNLEEGDV-------------------LFIDEIHRLSRVVEEILYPAMEDFRLdivigkgpaarsirldlppfTLVG 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 254540120 350 ATTenpsfqvNAALLS---RCRVIVLEKL---PVEAMVTILMRAINSLGI 393
Cdd:COG2255 159 ATT-------RAGLLTsplRDRFGIVLRLefyTVEELAEIVKRSARILGV 201
|
|
| ruvB |
PRK00080 |
Holliday junction branch migration DNA helicase RuvB; |
226-393 |
4.56e-18 |
|
Holliday junction branch migration DNA helicase RuvB;
Pssm-ID: 234619 [Multi-domain] Cd Length: 328 Bit Score: 85.95 E-value: 4.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 226 MRPDTLQDYIGQSRAVGQetlLRSLLEA----NEIPS-LILWGPPGCGKTTLAHIIAN--NSKkhsirFVTLSA------ 292
Cdd:PRK00080 19 LRPKSLDEFIGQEKVKEN---LKIFIEAakkrGEALDhVLLYGPPGLGKTTLANIIANemGVN-----IRITSGpalekp 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 293 -------TNAKTNDVrdvikqaqneksffkrktiLFIDEIHRFNKSQQDTFLPHVECGTI-------------------- 345
Cdd:PRK00080 91 gdlaailTNLEEGDV-------------------LFIDEIHRLSPVVEEILYPAMEDFRLdimigkgpaarsirldlppf 151
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 254540120 346 TLIGATTEnpsfqvnAALLS---RCR---VIVLEKLPVEAMVTILMRAINSLGI 393
Cdd:PRK00080 152 TLIGATTR-------AGLLTsplRDRfgiVQRLEFYTVEELEKIVKRSARILGV 198
|
|
| PRK04195 |
PRK04195 |
replication factor C large subunit; Provisional |
221-482 |
3.46e-16 |
|
replication factor C large subunit; Provisional
Pssm-ID: 235250 [Multi-domain] Cd Length: 482 Bit Score: 81.51 E-value: 3.46e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 221 PLADKMRPDTLQDYIGQSRAVGQ-ETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIANnskkhSIRF--VTLSATNAKT 297
Cdd:PRK04195 3 PWVEKYRPKTLSDVVGNEKAKEQlREWIESWLKGKPKKALLLYGPPGVGKTSLAHALAN-----DYGWevIELNASDQRT 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 298 NDV-RDVIKQAQNEKSFF-KRKTILFIDE---IHrfnkSQQDTflphvecG---TITLIGATTENPSfqVNAA------- 362
Cdd:PRK04195 78 ADViERVAGEAATSGSLFgARRKLILLDEvdgIH----GNEDR-------GgarAILELIKKAKQPI--ILTAndpydps 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 363 ---LLSRCRVIVLEKLPVEAMVTILmRAInslgihvldssrptdplshssnCSSEpSVFIEDKAVDTLAYLSDGDARTGL 439
Cdd:PRK04195 145 lreLRNACLMIEFKRLSTRSIVPVL-KRI----------------------CRKE-GIECDDEALKEIAERSGGDLRSAI 200
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 254540120 440 NGLQlavlARLSSRKVfckksgqtyspsrvlITENDVKEGLQR 482
Cdd:PRK04195 201 NDLQ----AIAEGYGK---------------LTLEDVKTLGRR 224
|
|
| RuvB_N |
pfam05496 |
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ... |
226-365 |
4.30e-16 |
|
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.
Pssm-ID: 398900 [Multi-domain] Cd Length: 159 Bit Score: 76.00 E-value: 4.30e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 226 MRPDTLQDYIGQSRAVGQetlLRSLLEA----NEIPS-LILWGPPGCGKTTLAHIIANNSKKhSIRfVT----------L 290
Cdd:pfam05496 1 LRPRTLDEYIGQEKVKEN---LKIFIEAakqrGEALDhVLLYGPPGLGKTTLANIIANEMGV-NIR-ITsgpaierpgdL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 291 SA--TNAKTNDVrdvikqaqneksffkrktiLFIDEIHRFNKSQQDTFLPHVECGTI--------------------TLI 348
Cdd:pfam05496 76 AAilTNLEPGDV-------------------LFIDEIHRLNRAVEEILYPAMEDFRLdivigkgpsarsirldlppfTLV 136
|
170
....*....|....*..
gi 254540120 349 GATTEnpsfqvnAALLS 365
Cdd:pfam05496 137 GATTR-------AGLLT 146
|
|
| ruvB |
TIGR00635 |
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ... |
230-393 |
8.00e-14 |
|
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129721 [Multi-domain] Cd Length: 305 Bit Score: 72.72 E-value: 8.00e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 230 TLQDYIGQSRAVGQetlLRSLLEA----NEIPS-LILWGPPGCGKTTLAHIIANNSKKhSIRfVTLSATNAKTNDVRDVI 304
Cdd:TIGR00635 2 LLAEFIGQEKVKEQ---LQLFIEAakmrQEALDhLLLYGPPGLGKTTLAHIIANEMGV-NLK-ITSGPALEKPGDLAAIL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 305 kqaqnekSFFKRKTILFIDEIHRFNKSQQDTFLPHVE-------------CGTI-------TLIGATTEnpSFQVNAALL 364
Cdd:TIGR00635 77 -------TNLEEGDVLFIDEIHRLSPAVEELLYPAMEdfrldivigkgpsARSVrldlppfTLVGATTR--AGMLTSPLR 147
|
170 180 190
....*....|....*....|....*....|
gi 254540120 365 SRCRVIV-LEKLPVEAMVTILMRAINSLGI 393
Cdd:TIGR00635 148 DRFGIILrLEFYTVEELAEIVSRSAGLLNV 177
|
|
| DnaX |
COG2812 |
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair]; |
228-456 |
9.63e-14 |
|
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
Pssm-ID: 442061 [Multi-domain] Cd Length: 340 Bit Score: 72.92 E-value: 9.63e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 228 PDTLQDYIGQSRAVgqETLLRSLlEANEIP-SLILWGPPGCGKTTLAHIIA---N-------------------NSKKHS 284
Cdd:COG2812 6 PQTFDDVVGQEHVV--RTLKNAL-ASGRLAhAYLFTGPRGVGKTTLARILAkalNcengptgepcgecescraiAAGSHP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 285 -IRFVTLSATNAKTNDVRDVIKQAQNeKSFFKRKTILFIDEIHRFNKSQQDTFL-------PHVecgtiTLIGATTEnPS 356
Cdd:COG2812 83 dVIEIDAEASNIGVDDIRELIEKVSY-APVEGRYKVYIIDEAHMLTTEAFNALLktleeppPHV-----VFILATTE-PQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 357 fQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHvldssrptdplshssncssepsvfIEDKAVDTLAYLSDGDAR 436
Cdd:COG2812 156 -KLLPTILSRCQRFDFRRLPPEEIAEHLAKIAEREGIE------------------------IEPEALALIARAADGSMR 210
|
250 260
....*....|....*....|.
gi 254540120 437 TGLNGL-QLAVLARLSSRKVF 456
Cdd:COG2812 211 DALSLLdQAIAFGLLDRRELL 231
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
258-375 |
1.05e-12 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 65.86 E-value: 1.05e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 258 SLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFF----------------KRKTILF 321
Cdd:smart00382 4 VILIVGPPGSGKTTLARALARELGPPGGGVIYIDGEDILEEVLDQLLLIIVGGKKASgsgelrlrlalalarkLKPDVLI 83
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254540120 322 IDEIHRFNKSQQD----------TFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEKL 375
Cdd:smart00382 84 LDEITSLLDAEQEallllleelrLLLLLKSEKNLTVILTTNDEKDLGPALLRRRFDRRIVLLLI 147
|
|
| PRK05896 |
PRK05896 |
DNA polymerase III subunits gamma and tau; Validated |
225-443 |
3.20e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235638 [Multi-domain] Cd Length: 605 Bit Score: 69.49 E-value: 3.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 225 KMRPDTLQDYIGQSRAvgQETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIA--------------NN-------SKKH 283
Cdd:PRK05896 9 KYRPHNFKQIIGQELI--KKILVNAILNNKLTHAYIFSGPRGIGKTSIAKIFAkainclnpkdgdccNScsvcesiNTNQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 284 SIRFVTL-SATNAKTNDVRDVIKQAQNEKSFFKRKtILFIDEIHRFNKSQQDTFLPHVE--CGTITLIGATTEnpSFQVN 360
Cdd:PRK05896 87 SVDIVELdAASNNGVDEIRNIIDNINYLPTTFKYK-VYIIDEAHMLSTSAWNALLKTLEepPKHVVFIFATTE--FQKIP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 361 AALLSRCRVIVLEKLPveamvtilmraiNSLGIHVLDssrptdplshssNCSSEPSVFIEDKAVDTLAYLSDGDARTGLN 440
Cdd:PRK05896 164 LTIISRCQRYNFKKLN------------NSELQELLK------------SIAKKEKIKIEDNAIDKIADLADGSLRDGLS 219
|
...
gi 254540120 441 GLQ 443
Cdd:PRK05896 220 ILD 222
|
|
| 44 |
PHA02544 |
clamp loader, small subunit; Provisional |
225-370 |
3.55e-12 |
|
clamp loader, small subunit; Provisional
Pssm-ID: 222866 [Multi-domain] Cd Length: 316 Bit Score: 67.71 E-value: 3.55e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 225 KMRPDTLQDYIGQSravGQETLLRSLLEANEIPSLILWGP-PGCGKTTLAHIIANNSkkhSIRFVTLSATNAKTNDVRDV 303
Cdd:PHA02544 14 KYRPSTIDECILPA---ADKETFKSIVKKGRIPNMLLHSPsPGTGKTTVAKALCNEV---GAEVLFVNGSDCRIDFVRNR 87
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 254540120 304 IKQAQNEKSFFKRKTILFIDEIHRfnksqqdTFLPHVECGTITLIGATTENPSF--------QVNAALLSRCRVI 370
Cdd:PHA02544 88 LTRFASTVSLTGGGKVIIIDEFDR-------LGLADAQRHLRSFMEAYSKNCSFiitannknGIIEPLRSRCRVI 155
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
222-394 |
7.18e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 68.58 E-value: 7.18e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYIGQSRAVgqETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIANN------------------SKKH 283
Cdd:PRK08691 6 LARKWRPKTFADLVGQEHVV--KALQNALDEGRLHHAYLLTGTRGVGKTTIARILAKSlncenaqhgepcgvcqscTQID 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 284 SIRFVTL----SATNAKTNDVRDVIKQAQNEKSFFKRKtILFIDEIHRFNKSQQDTFLPHVE--CGTITLIGATTEnpSF 357
Cdd:PRK08691 84 AGRYVDLleidAASNTGIDNIREVLENAQYAPTAGKYK-VYIIDEVHMLSKSAFNAMLKTLEepPEHVKFILATTD--PH 160
|
170 180 190
....*....|....*....|....*....|....*..
gi 254540120 358 QVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIH 394
Cdd:PRK08691 161 KVPVTVLSRCLQFVLRNMTAQQVADHLAHVLDSEKIA 197
|
|
| PRK14953 |
PRK14953 |
DNA polymerase III subunits gamma and tau; Provisional |
221-480 |
1.59e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237867 [Multi-domain] Cd Length: 486 Bit Score: 67.16 E-value: 1.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 221 PLADKMRPDTLQDYIGQsravgqETLLRSLLEANEIPSL----ILWGPPGCGKTTLAHIIAN--NSKK------------ 282
Cdd:PRK14953 5 PFARKYRPKFFKEVIGQ------EIVVRILKNAVKLQRVshayIFAGPRGTGKTTIARILAKvlNCLNpqegepcgkcen 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 283 -HSIR---FVTL----SATNAKTNDVRdVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVE---CGTItLIGAT 351
Cdd:PRK14953 79 cVEIDkgsFPDLieidAASNRGIDDIR-ALRDAVSYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEeppPRTI-FILCT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 352 TEnpSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHvldssrptdplshssncssepsvfIEDKAVDTLAYLS 431
Cdd:PRK14953 157 TE--YDKIPPTILSRCQRFIFSKPTKEQIKEYLKRICNEEKIE------------------------YEEKALDLLAQAS 210
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 254540120 432 DGDARTGLNGLQLAVlarlssrkvfckksgqTYSPSRVliTENDVKEGL 480
Cdd:PRK14953 211 EGGMRDAASLLDQAS----------------TYGEGKV--TIKVVEEFL 241
|
|
| PLN03025 |
PLN03025 |
replication factor C subunit; Provisional |
221-443 |
1.90e-11 |
|
replication factor C subunit; Provisional
Pssm-ID: 178596 [Multi-domain] Cd Length: 319 Bit Score: 65.52 E-value: 1.90e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 221 PLADKMRPDTLQDYIGQSRAVGQetlLRSLLEANEIPSLILWGPPGCGKTT----LAHIIANNSKKHSIrfVTLSATNAK 296
Cdd:PLN03025 2 PWVEKYRPTKLDDIVGNEDAVSR---LQVIARDGNMPNLILSGPPGTGKTTsilaLAHELLGPNYKEAV--LELNASDDR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 297 TND-VRDVIKQ-AQNEKSFFK-RKTILFIDEIHRFNKSQQDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLE 373
Cdd:PLN03025 77 GIDvVRNKIKMfAQKKVTLPPgRHKIVILDEADSMTSGAQQALRRTMEIYSNTTRFALACNTSSKIIEPIQSRCAIVRFS 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 374 KLPVEAMVTILMRAinslgihvldssrptdplshssnCSSEpSVFIEDKAVDTLAYLSDGDARTGLNGLQ 443
Cdd:PLN03025 157 RLSDQEILGRLMKV-----------------------VEAE-KVPYVPEGLEAIIFTADGDMRQALNNLQ 202
|
|
| PRK14970 |
PRK14970 |
DNA polymerase III subunits gamma and tau; Provisional |
223-506 |
2.04e-11 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184934 [Multi-domain] Cd Length: 367 Bit Score: 66.05 E-value: 2.04e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 223 ADKMRPDTLQDYIGQSRAVgqeTLLRSLLEANEIPSLILW-GPPGCGKTTLAHIIA-----------NNSKKHSIrFVTL 290
Cdd:PRK14970 8 ARKYRPQTFDDVVGQSHIT---NTLLNAIENNHLAQALLFcGPRGVGKTTCARILArkinqpgyddpNEDFSFNI-FELD 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 291 SATNAKTNDVRDVIKQAQNEKSFFKRKtILFIDEIHRFNKSQQDTFLPHVE--CGTITLIGATTENpsFQVNAALLSRCR 368
Cdd:PRK14970 84 AASNNSVDDIRNLIDQVRIPPQTGKYK-IYIIDEVHMLSSAAFNAFLKTLEepPAHAIFILATTEK--HKIIPTILSRCQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 369 VIVLEKLPVEamvtilmrainslgihvldssrptDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGlnglqLAVLA 448
Cdd:PRK14970 161 IFDFKRITIK------------------------DIKEHLAGIAVKEGIKFEDDALHIIAQKADGALRDA-----LSIFD 211
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 254540120 449 RLSSrkvFCKKS--------------GQTYSPSRVLITENDVKEGLqrshILYD---RAGEEHYNCISALHKAMR 506
Cdd:PRK14970 212 RVVT---FCGKNitrqavtenlnildYDTYINVTDLILENKIPELL----LAFNeilRKGFDGHHFIAGLASHFR 279
|
|
| rfc |
PRK00440 |
replication factor C small subunit; Reviewed |
223-445 |
3.45e-11 |
|
replication factor C small subunit; Reviewed
Pssm-ID: 234763 [Multi-domain] Cd Length: 319 Bit Score: 64.89 E-value: 3.45e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 223 ADKMRPDTLQDYIGQSRAVGQetlLRSLLEANEIPSLILWGPPGCGKTTLAHIIA-----NNSKKHsirFVTLSATNAKT 297
Cdd:PRK00440 8 VEKYRPRTLDEIVGQEEIVER---LKSYVKEKNMPHLLFAGPPGTGKTTAALALArelygEDWREN---FLELNASDERG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 298 NDV-RDVIKQAQNEKSF----FKrktILFIDEIHRFNKSQQdtflpHVECGTITLIGATTE-----NPSFQVNAALLSRC 367
Cdd:PRK00440 82 IDViRNKIKEFARTAPVggapFK---IIFLDEADNLTSDAQ-----QALRRTMEMYSQNTRfilscNYSSKIIDPIQSRC 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 254540120 368 RVIVLEKLPVEAMVTILmRAInslgihvldssrptdplshssnCSSEpSVFIEDKAVDTLAYLSDGDARTGLNGLQLA 445
Cdd:PRK00440 154 AVFRFSPLKKEAVAERL-RYI----------------------AENE-GIEITDDALEAIYYVSEGDMRKAINALQAA 207
|
|
| SpoVK |
COG0464 |
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ... |
259-384 |
2.57e-10 |
|
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];
Pssm-ID: 440232 [Multi-domain] Cd Length: 397 Bit Score: 63.01 E-value: 2.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSKKHSIRfVTLSA--------TNAKtndVRDVIKQAQNEKsffkrKTILFIDEI----- 325
Cdd:COG0464 194 LLLYGPPGTGKTLLARALAGELGLPLIE-VDLSDlvskyvgeTEKN---LREVFDKARGLA-----PCVLFIDEAdalag 264
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 254540120 326 ------HRFNKSQQDTFLPHVECGT--ITLIGATteNPSFQVNAALLSRCRVIVLEKLP-VEAMVTIL 384
Cdd:COG0464 265 krgevgDGVGRRVVNTLLTEMEELRsdVVVIAAT--NRPDLLDPALLRRFDEIIFFPLPdAEERLEIF 330
|
|
| HLD_clamp_RarA |
cd18139 |
helical lid domain of recombination factor protein RarA; Recombination factor RarA ... |
375-481 |
3.07e-10 |
|
helical lid domain of recombination factor protein RarA; Recombination factor RarA (Replication associated recombination gene/protein A, also known as MgsA (Maintenance of genome stability A) or Mgs1 in yeast and WRNIP1 in mammals) is a member of the clamp-loader clade of the AAA+ superfamily. It functions as a tetramer. RarA co-localize with the replication fork throughout the cell cycle and may play a role in the rescue of stalled replication forks.
Pssm-ID: 350841 [Multi-domain] Cd Length: 75 Bit Score: 56.49 E-value: 3.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 375 LPVEAMVTILMRAINSLGIHvldssrptdplshssncsSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARLSSRk 454
Cdd:cd18139 1 LSEEDLEKLLKRALEDKERG------------------GDRKVTIDDEALELLAEAADGDARSALNLLELAVLSAEEDG- 61
|
90 100
....*....|....*....|....*..
gi 254540120 455 vfckksgqtyspsRVLITENDVKEGLQ 481
Cdd:cd18139 62 -------------GIVITLEDLEEVLQ 75
|
|
| RPT1 |
COG1222 |
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ... |
208-325 |
3.39e-10 |
|
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440835 [Multi-domain] Cd Length: 326 Bit Score: 61.95 E-value: 3.39e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 208 LAAEEIRQMLEGKPLADKMRPDTLQDYIGqsravGQETLLRSLLEANEIP----------------SLILWGPPGCGKTT 271
Cdd:COG1222 53 ANLTQKRLGTPRGTAVPAESPDVTFDDIG-----GLDEQIEEIREAVELPlknpelfrkygieppkGVLLYGPPGTGKTL 127
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 254540120 272 LAHIIANNSKKHSIR---------FVTLSATNaktndVRDVIKQAQNeksffKRKTILFIDEI 325
Cdd:COG1222 128 LAKAVAGELGAPFIRvrgselvskYIGEGARN-----VREVFELARE-----KAPSIIFIDEI 180
|
|
| PRK12402 |
PRK12402 |
replication factor C small subunit 2; Reviewed |
224-448 |
3.57e-10 |
|
replication factor C small subunit 2; Reviewed
Pssm-ID: 237090 [Multi-domain] Cd Length: 337 Bit Score: 61.93 E-value: 3.57e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 224 DKMRPDTLQDYIGQSRAVGQetlLRSLLEANEIPSLILWGPPGCGKTT----LAHIIANNSKKHSI-------------- 285
Cdd:PRK12402 7 EKYRPALLEDILGQDEVVER---LSRAVDSPNLPHLLVQGPPGSGKTAavraLARELYGDPWENNFtefnvadffdqgkk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 286 ------RFVTLSATNAKTN-DVRDVIKQAQNEKSFFKR-----KTILFiDEIHRFNKSQQDTFLPHVE--CGTITLIGAT 351
Cdd:PRK12402 84 ylvedpRFAHFLGTDKRIRsSKIDNFKHVLKEYASYRPlsadyKTILL-DNAEALREDAQQALRRIMEqySRTCRFIIAT 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 352 TeNPSfQVNAALLSRCRVIVLEKLPVEAMVTILmrainslgIHVLDSSRptdplshssncssepsVFIEDKAVDTLAYLS 431
Cdd:PRK12402 163 R-QPS-KLIPPIRSRCLPLFFRAPTDDELVDVL--------ESIAEAEG----------------VDYDDDGLELIAYYA 216
|
250
....*....|....*..
gi 254540120 432 DGDARTGLNGLQLAVLA 448
Cdd:PRK12402 217 GGDLRKAILTLQTAALA 233
|
|
| PRK14964 |
PRK14964 |
DNA polymerase III subunits gamma and tau; Provisional |
222-488 |
2.10e-09 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237870 [Multi-domain] Cd Length: 491 Bit Score: 60.18 E-value: 2.10e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYigqsraVGQETLLRSLLEA---NEIP-SLILWGPPGCGKTTLAHIIA-------------------- 277
Cdd:PRK14964 3 LALKYRPSSFKDL------VGQDVLVRILRNAftlNKIPqSILLVGASGVGKTTCARIISlclncsngptsdpcgtchnc 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 278 ----NNSKKHSIRFVtlSATNAKTNDVRdVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFL-------PHVEcgtit 346
Cdd:PRK14964 77 isikNSNHPDVIEID--AASNTSVDDIK-VILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLktleepaPHVK----- 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 347 LIGATTENPSFQVNAAllSRCRVIVLEKLPVEAMVTilmrainslgihvldssrptdplsHSSNCSSEPSVFIEDKAVDT 426
Cdd:PRK14964 149 FILATTEVKKIPVTII--SRCQRFDLQKIPTDKLVE------------------------HLVDIAKKENIEHDEESLKL 202
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254540120 427 LAYLSDGDARtglNGLQLAVLARLSSRKVfckksgqtyspsrvlITENDVKE--GLQRSHILYD 488
Cdd:PRK14964 203 IAENSSGSMR---NALFLLEQAAIYSNNK---------------ISEKSVRDllGCVDKHILED 248
|
|
| HolB |
COG0470 |
DNA polymerase III, delta prime subunit [Replication, recombination and repair]; |
244-449 |
3.80e-09 |
|
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
Pssm-ID: 440238 [Multi-domain] Cd Length: 289 Bit Score: 58.45 E-value: 3.80e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 244 ETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIAN------------NSKKHSIR--------FVTLSATNAKT----ND 299
Cdd:COG0470 6 EQLLAAAESGRLPHALLLHGPPGIGKTTLALALARdllcenpeggkaCGQCHSRLmaagnhpdLLELNPEEKSDqigiDQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 300 VRDVIKQAQNeKSFFKRKTILFIDEIHRFNKSQQDTFL-----PHVECgTITLIgatTENPSfQVNAALLSRCRVIVLEK 374
Cdd:COG0470 86 IRELGEFLSL-TPLEGGRKVVIIDEADAMNEAAANALLktleePPKNT-PFILI---ANDPS-RLLPTIRSRCQVIRFRP 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 254540120 375 LPVEAMVTILMRAinslgihvldssrptdplshssncssepsvFIEDKAVDTLAYLSDGDARTGLNGLQLAVLAR 449
Cdd:COG0470 160 PSEEEALAWLREE------------------------------GVDEDALEAILRLAGGDPRAAINLLQALAGRK 204
|
|
| ZnF_Rad18 |
smart00734 |
Rad18-like CCHC zinc finger; Yeast Rad18p functions with Rad5p in error-free post-replicative ... |
17-40 |
4.69e-09 |
|
Rad18-like CCHC zinc finger; Yeast Rad18p functions with Rad5p in error-free post-replicative DNA repair. This zinc finger is likely to bind nucleic-acids.
Pssm-ID: 128973 [Multi-domain] Cd Length: 24 Bit Score: 51.84 E-value: 4.69e-09
|
| zf-WRNIP1_ubi |
pfam18279 |
Werner helicase-interacting protein 1 ubiquitin-binding domain; This domain is found in the ... |
16-36 |
6.62e-09 |
|
Werner helicase-interacting protein 1 ubiquitin-binding domain; This domain is found in the Werner helicase-interacting protein 1 present in Homo sapiens. The domain is a zinc finger responsible and has a zinc-coordinating B-B-A fold. WRNIP1 UBZ binds ubiquitin in a similar manner to Rad18 UBZ.
Pssm-ID: 375706 Cd Length: 21 Bit Score: 51.36 E-value: 6.62e-09
|
| PRK06647 |
PRK06647 |
DNA polymerase III subunits gamma and tau; Validated |
223-397 |
7.21e-09 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 235845 [Multi-domain] Cd Length: 563 Bit Score: 58.63 E-value: 7.21e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 223 ADKMRPDTLQDYIGQSRAVgqETLLRSLlEANEI-PSLILWGPPGCGKTTLAHIIAN--NSKK----------------- 282
Cdd:PRK06647 7 ATKRRPRDFNSLEGQDFVV--ETLKHSI-ESNKIaNAYIFSGPRGVGKTSSARAFARclNCVNgptpmpcgecsscksid 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 283 --HSIRFVTLS-ATNAKTNDVRdvikQAQNEKSF---FKRKTILFIDEIHRFNKSQQDTFLPHVE--CGTITLIGATTEn 354
Cdd:PRK06647 84 ndNSLDVIEIDgASNTSVQDVR----QIKEEIMFppaSSRYRVYIIDEVHMLSNSAFNALLKTIEepPPYIVFIFATTE- 158
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 254540120 355 pSFQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLD 397
Cdd:PRK06647 159 -VHKLPATIKSRCQHFNFRLLSLEKIYNMLKKVCLEDQIKYED 200
|
|
| RecA-like_protease |
cd19481 |
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ... |
239-369 |
8.93e-08 |
|
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410889 [Multi-domain] Cd Length: 158 Bit Score: 51.90 E-value: 8.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 239 RAVGQETLLRSLLEANEIP--SLILWGPPGCGKTTLAHIIANNSKKHSIRfVTLSATNAKTND-----VRDVIKQAQNek 311
Cdd:cd19481 7 EAVEAPRRGSRLRRYGLGLpkGILLYGPPGTGKTLLAKALAGELGLPLIV-VKLSSLLSKYVGeseknLRKIFERARR-- 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254540120 312 sffKRKTILFIDEIH-----RFNKSQQDTFLPHV-----------ECGTITLIGATteNPSFQVNAALLSRCRV 369
Cdd:cd19481 84 ---LAPCILFIDEIDaigrkRDSSGESGELRRVLnqllteldgvnSRSKVLVIAAT--NRPDLLDPALLRPGRF 152
|
|
| rad24 |
TIGR00602 |
checkpoint protein rad24; All proteins in this family for which functions are known are ... |
218-464 |
9.81e-08 |
|
checkpoint protein rad24; All proteins in this family for which functions are known are involved in DNA damage tolerance (likely cell cycle checkpoints).This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129690 [Multi-domain] Cd Length: 637 Bit Score: 55.35 E-value: 9.81e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 218 EGKPLADKMRPDTLQDYIGQSRAVG--QETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIA--------NNSKKHSIRF 287
Cdd:TIGR00602 70 GNEPWVEKYKPETQHELAVHKKKIEevETWLKAQVLENAPKRILLITGPSGCGKSTTIKILSkelgiqvqEWSNPTLPDF 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 288 ------VTLSATNAKTNDV------RDVIKQAQNE-----KSFFKRKTILFIDEI----HRFNKSQQDTF-LPHVECGTI 345
Cdd:TIGR00602 150 qkndhkVTLSLESCFSNFQsqievfSEFLLRATNKlqmlgDDLMTDKKIILVEDLpnqfYRDTRALHEILrWKYVSIGRC 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 346 TLIGATTEN------------PSFQV-NAALLSRCRVIVLEKLPVEAmvTILMRAINSLgihvldssrptdpLSHSSNCS 412
Cdd:TIGR00602 230 PLVFIITESlegdnnqrrllfPAETImNKEILEEPRVSNISFNPIAP--TIMKKFLNRI-------------VTIEAKKN 294
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 254540120 413 SEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVlARLSSRKVFCKKSGQTY 464
Cdd:TIGR00602 295 GEKIKVPKKTSVELLCQGCSGDIRSAINSLQFSS-SKSGSLPIKKRMSTKSD 345
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
225-443 |
1.04e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 55.20 E-value: 1.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 225 KMRPDTLQDYIGQSRAVgqeTLLRSLLEANEIPSLILW-GPPGCGKTTLAHIIA------NNSKK--------------- 282
Cdd:PRK14950 9 KWRSQTFAELVGQEHVV---QTLRNAIAEGRVAHAYLFtGPRGVGKTSTARILAkavnctTNDPKgrpcgtcemcraiae 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 283 -HSIRFVTL-SATNAKTNDVRDVIKQAQNEKSFFkRKTILFIDEIHRFNKSQQDTFL-------PHVecgtiTLIGATTE 353
Cdd:PRK14950 86 gSAVDVIEMdAASHTSVDDAREIIERVQFRPALA-RYKVYIIDEVHMLSTAAFNALLktleeppPHA-----IFILATTE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 354 npSFQVNAALLSRCRVIVLEKLPVEAMVtilmrainslgihvldssrptdplSHSSNCSSEPSVFIEDKAVDTLAYLSDG 433
Cdd:PRK14950 160 --VHKVPATILSRCQRFDFHRHSVADMA------------------------AHLRKIAAAEGINLEPGALEAIARAATG 213
|
250
....*....|
gi 254540120 434 DARTGLNGLQ 443
Cdd:PRK14950 214 SMRDAENLLQ 223
|
|
| PRK14971 |
PRK14971 |
DNA polymerase III subunit gamma/tau; |
223-381 |
3.84e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237874 [Multi-domain] Cd Length: 614 Bit Score: 53.24 E-value: 3.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 223 ADKMRPDTLQDYIGQSRAVgqeTLLRSLLEANEIPSLILW-GPPGCGKTTLAHIIANN---------------------- 279
Cdd:PRK14971 8 ARKYRPSTFESVVGQEALT---TTLKNAIATNKLAHAYLFcGPRGVGKTTCARIFAKTincqnltadgeacnecescvaf 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 280 SKKHSIRFVTL-SATNAKTNDVRDVIKQAQNEKSFFKRKtILFIDEIHRFNKSQQDTFL------PHvecgTITLIGATT 352
Cdd:PRK14971 85 NEQRSYNIHELdAASNNSVDDIRNLIEQVRIPPQIGKYK-IYIIDEVHMLSQAAFNAFLktleepPS----YAIFILATT 159
|
170 180
....*....|....*....|....*....
gi 254540120 353 ENpsFQVNAALLSRCRVIVLEKLPVEAMV 381
Cdd:PRK14971 160 EK--HKILPTILSRCQIFDFNRIQVADIV 186
|
|
| COG1373 |
COG1373 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
247-330 |
6.03e-07 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440984 [Multi-domain] Cd Length: 405 Bit Score: 52.25 E-value: 6.03e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 247 LRSLLEANEIpsLILWGPPGCGKTTLA-HIIANNSKKHSIRFVTLSATNAKTNDVRDVIKQAqneKSFFKRKTILFIDEI 325
Cdd:COG1373 13 LLKLLDNRKA--VVITGPRQVGKTTLLkQLAKELENILYINLDDPRLRALAEEDPDDLLEAL---KELYPGKTYLFLDEI 87
|
....*
gi 254540120 326 HRFNK 330
Cdd:COG1373 88 QRVPE 92
|
|
| COG1223 |
COG1223 |
Predicted ATPase, AAA+ superfamily [General function prediction only]; |
231-395 |
8.01e-07 |
|
Predicted ATPase, AAA+ superfamily [General function prediction only];
Pssm-ID: 440836 [Multi-domain] Cd Length: 246 Bit Score: 50.65 E-value: 8.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 231 LQDYIGQSRAVGQETLLRSLLEANEIP---------SLILWGPPGCGKTTLAHIIANNSKKHSI---------RFVTLSA 292
Cdd:COG1223 1 LDDVVGQEEAKKKLKLIIKELRRRENLrkfglwpprKILFYGPPGTGKTMLAEALAGELKLPLLtvrldsligSYLGETA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 293 TNaktndVRDVIKQAQNeksffkRKTILFIDEIH-----RFNKS-------------QQDTFLPhvecGTITLIGATteN 354
Cdd:COG1223 81 RN-----LRKLFDFARR------APCVIFFDEFDaiakdRGDQNdvgevkrvvnallQELDGLP----SGSVVIAAT--N 143
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 254540120 355 PSFQVNAALLSRCRVIVLEKLP-VEAMVTILMRAINSLGIHV 395
Cdd:COG1223 144 HPELLDSALWRRFDEVIEFPLPdKEERKEILELNLKKFPLPF 185
|
|
| PRK14961 |
PRK14961 |
DNA polymerase III subunits gamma and tau; Provisional |
222-496 |
8.99e-07 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184925 [Multi-domain] Cd Length: 363 Bit Score: 51.35 E-value: 8.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYIGQSRAVgqETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIANN---------------------S 280
Cdd:PRK14961 6 LARKWRPQYFRDIIGQKHIV--TAISNGLSLGRIHHAWLLSGTRGVGKTTIARLLAKSlncqngitsnpcrkciickeiE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 281 KKHSIRFVTL-SATNAKTNDVRDVIKQAQNE--KSFFKrktILFIDEIHRFNKSQQDTFLPHVE--CGTITLIGATTENP 355
Cdd:PRK14961 84 KGLCLDLIEIdAASRTKVEEMREILDNIYYSpsKSRFK---VYLIDEVHMLSRHSFNALLKTLEepPQHIKFILATTDVE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 356 sfQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVldssrptdplshssncssepsvfiEDKAVDTLAYLSDGDA 435
Cdd:PRK14961 161 --KIPKTILSRCLQFKLKIISEEKIFNFLKYILIKESIDT------------------------DEYALKLIAYHAHGSM 214
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 254540120 436 RTGLNGLQLAVlaRLS----SRKVFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYN 496
Cdd:PRK14961 215 RDALNLLEHAI--NLGkgniNIKNVTDMLGLLNEKQSFLLTDALLKKDSKKTMLLLNKISSIGIE 277
|
|
| PRK14962 |
PRK14962 |
DNA polymerase III subunits gamma and tau; Provisional |
222-395 |
1.27e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237869 [Multi-domain] Cd Length: 472 Bit Score: 51.30 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYIGQSRAvgqETLLRSLLEANEIP-SLILWGPPGCGKTTLAHIIA---NNSKKHSIR----------- 286
Cdd:PRK14962 4 LYRKYRPKTFSEVVGQDHV---KKLIINALKKNSIShAYIFAGPRGTGKTTVARILAkslNCENRKGVEpcnecracrsi 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 287 ----FVTL----SATNAKTNDVRDvIKQAQNEKSFFKRKTILFIDEIHRFNKSQQDTFLPHVE--CGTITLIGATTeNPS 356
Cdd:PRK14962 81 degtFMDVieldAASNRGIDEIRK-IRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEepPSHVVFVLATT-NLE 158
|
170 180 190
....*....|....*....|....*....|....*....
gi 254540120 357 fQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHV 395
Cdd:PRK14962 159 -KVPPTIISRCQVIEFRNISDELIIKRLQEVAEAEGIEI 196
|
|
| DnaA |
COG0593 |
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair]; |
259-336 |
2.99e-06 |
|
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
Pssm-ID: 440358 [Multi-domain] Cd Length: 303 Bit Score: 49.42 E-value: 2.99e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSKKH--SIRFVTLSA---TNAKTNDVRDviKQAQNEKSFFKRKTILFIDEIHRF--NKS 331
Cdd:COG0593 37 LFLYGGVGLGKTHLLHAIGNEALENnpGARVVYLTAeefTNDFINAIRN--NTIEEFKEKYRSVDVLLIDDIQFLagKEA 114
|
....*
gi 254540120 332 QQDTF 336
Cdd:COG0593 115 TQEEF 119
|
|
| RecA-like_NVL_r1-like |
cd19518 |
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
259-325 |
3.28e-06 |
|
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410926 [Multi-domain] Cd Length: 169 Bit Score: 47.78 E-value: 3.28e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSKkhsIRFVTLSATN-------AKTNDVRDVIKQAQNEKSffkrkTILFIDEI 325
Cdd:cd19518 37 VLLHGPPGCGKTMLANAIAGELK---VPFLKISATEivsgvsgESEEKIRELFDQAISNAP-----CIVFIDEI 102
|
|
| PRK14956 |
PRK14956 |
DNA polymerase III subunits gamma and tau; Provisional |
222-380 |
4.36e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184920 [Multi-domain] Cd Length: 484 Bit Score: 49.56 E-value: 4.36e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYIGQSRAVGQetlLRSLLEANEIP-SLILWGPPGCGKTTLAHIIA---------NNSKKHSIRfVTLS 291
Cdd:PRK14956 8 LSRKYRPQFFRDVIHQDLAIGA---LQNALKSGKIGhAYIFFGPRGVGKTTIARILAkrlncenpiGNEPCNECT-SCLE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 292 ATNAKTNDVRDV----------IKQAQNEKSFFK---RKTILFIDEIHRFNKSQQDTFLPHVE--CGTITLIGATTEnpS 356
Cdd:PRK14956 84 ITKGISSDVLEIdaasnrgienIRELRDNVKFAPmggKYKVYIIDEVHMLTDQSFNALLKTLEepPAHIVFILATTE--F 161
|
170 180
....*....|....*....|....
gi 254540120 357 FQVNAALLSRCRVIVLEKLPVEAM 380
Cdd:PRK14956 162 HKIPETILSRCQDFIFKKVPLSVL 185
|
|
| Rad17 |
pfam03215 |
Rad17 P-loop domain; |
218-376 |
1.47e-05 |
|
Rad17 P-loop domain;
Pssm-ID: 367398 [Multi-domain] Cd Length: 186 Bit Score: 46.10 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 218 EGKPLADKMRPDTLQDYIGQSRAVG--QETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIannSKKHSIRFVT-LSATN 294
Cdd:pfam03215 5 GGEQWYEKYKPNCLEQLAVHKRKIKdvQEWLDAMFLENAKHRILLISGPSGCGKSTVIKEL---SKELGPKYREwSNPTS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 295 AKTNDvrdvikqaqNEKSFFKRKTILFideihrfnksqqDTFLPHVECGTITLIGATTENPSFQVNAALLSRCRVIVLEK 374
Cdd:pfam03215 82 FRSPP---------NQVTDFRGDCIVN------------SRFLSQMESFSEFELKGARYLVMQKRGKNAQGNKKLILIED 140
|
..
gi 254540120 375 LP 376
Cdd:pfam03215 141 LP 142
|
|
| PRK03992 |
PRK03992 |
proteasome-activating nucleotidase; Provisional |
221-325 |
1.78e-05 |
|
proteasome-activating nucleotidase; Provisional
Pssm-ID: 179699 [Multi-domain] Cd Length: 389 Bit Score: 47.52 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 221 PLADKM----RPDTLQDYIGqsravGQETLLRSLLEANEIP----------------SLILWGPPGCGKTTLAHIIANNS 280
Cdd:PRK03992 115 PRVQAMevieSPNVTYEDIG-----GLEEQIREVREAVELPlkkpelfeevgieppkGVLLYGPPGTGKTLLAKAVAHET 189
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 254540120 281 KKHSIRFVTLSATN------AKTndVRDVIKQAQnEKSffkrKTILFIDEI 325
Cdd:PRK03992 190 NATFIRVVGSELVQkfigegARL--VRELFELAR-EKA----PSIIFIDEI 233
|
|
| ftsH |
CHL00176 |
cell division protein; Validated |
248-325 |
2.53e-05 |
|
cell division protein; Validated
Pssm-ID: 214386 [Multi-domain] Cd Length: 638 Bit Score: 47.35 E-value: 2.53e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 248 RSLLEANEIPS-LILWGPPGCGKTTLAHIIANNSKK--HSI-------RFVTLSATNaktndVRDVIKQAQNeksffKRK 317
Cdd:CHL00176 207 RFTAVGAKIPKgVLLVGPPGTGKTLLAKAIAGEAEVpfFSIsgsefveMFVGVGAAR-----VRDLFKKAKE-----NSP 276
|
....*...
gi 254540120 318 TILFIDEI 325
Cdd:CHL00176 277 CIVFIDEI 284
|
|
| AAA_14 |
pfam13173 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
259-327 |
2.98e-05 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 463799 [Multi-domain] Cd Length: 128 Bit Score: 44.12 E-value: 2.98e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 254540120 259 LILWGPPGCGKTTLA-HIIANNSKKHSIRFVTL---SATNAKTNDVRDVIkqaqnEKSFFKRKTILFIDEIHR 327
Cdd:pfam13173 5 LVITGPRQVGKTTLLlQLIKELLPPENILYINLddpRLLKLADFELLELF-----LELLYPGKTYLFLDEIQR 72
|
|
| DNA_pol3_delta2 |
pfam13177 |
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ... |
236-376 |
3.22e-05 |
|
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.
Pssm-ID: 433013 [Multi-domain] Cd Length: 161 Bit Score: 44.51 E-value: 3.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 236 GQSRAVgqeTLLRSLLEANEIPSLILW-GPPGCGKTTLAHIIA-----------------NNSKK-----HS-IRFVTLS 291
Cdd:pfam13177 1 GQPEAI---QLLQNSLENGRLSHAYLFsGPEGVGKLELALAFAkalfceepgddlpcgqcRSCRRiesgnHPdLVIIEPE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 292 ATNAKTNDVRDVIKQAQnEKSFFKRKTILFIDEIHRFNKSQQDTFL-----PHVEcgtiTLIGATTENPSfQVNAALLSR 366
Cdd:pfam13177 78 GQSIKIDQIRELQKEFS-KSPYEGKKKVYIIEDAEKMTASAANSLLkfleePPGN----TVIILLTENPS-RLLPTIRSR 151
|
170
....*....|
gi 254540120 367 CRVIVLEKLP 376
Cdd:pfam13177 152 CQIIRFKPLS 161
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
258-367 |
3.60e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 43.82 E-value: 3.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 258 SLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSAtNAKTNDVRDVIKQAQNEKSF--------FKRKTILFIDEIHRFN 329
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLTR-DTTEEDLFGRRNIDPGGASWvdgplvraAREGEIAVLDEINRAN 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 254540120 330 KSQQDTFLP-------HVECGT---------ITLIgATTENPSFQVN---AALLSRC 367
Cdd:pfam07728 80 PDVLNSLLSllderrlLLPDGGelvkaapdgFRLI-ATMNPLDRGLNelsPALRSRF 135
|
|
| RecA-like_CDC48_r2-like |
cd19511 |
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ... |
260-325 |
4.13e-05 |
|
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410919 [Multi-domain] Cd Length: 159 Bit Score: 44.20 E-value: 4.13e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 254540120 260 ILWGPPGCGKTTLAHIIANNSKkhsIRFVTLSATNAKT-------NDVRDVIKQAQNEKSffkrkTILFIDEI 325
Cdd:cd19511 31 LLYGPPGCGKTLLAKALASEAG---LNFISVKGPELFSkyvgeseRAVREIFQKARQAAP-----CIIFFDEI 95
|
|
| cell_div_CdvC |
NF041006 |
cell division protein CdvC; |
211-325 |
5.49e-05 |
|
cell division protein CdvC;
Pssm-ID: 468935 [Multi-domain] Cd Length: 371 Bit Score: 45.88 E-value: 5.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 211 EEIRQMLEGKPLADKMRPDTLQDYIGQSRA-------VGQETLLRSLLEANEIPS-------------LILWGPPGCGKT 270
Cdd:NF041006 69 EVLEELVPAEPAGPDVEKESDEELVVKEKPkvtfsdiVGLEDVKEALKEAIVYPSkrpdlfplgwprgILLYGPPGCGKT 148
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 254540120 271 TLAHIIANNSKKHsirFVTLSATN--------AKTNdVRDVIKQAQNEKSFFKRKTILFIDEI 325
Cdd:NF041006 149 MLAAAVANEIDSE---FIHVDAASimskwlgeAEKN-VAKIFKKAREKSKEEGKPAIIFIDEI 207
|
|
| RecA-like_PAN_like |
cd19502 |
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ... |
260-325 |
5.65e-05 |
|
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410910 [Multi-domain] Cd Length: 171 Bit Score: 44.25 E-value: 5.65e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 260 ILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATNAKTND----VRDVIKQAQNeksffKRKTILFIDEI 325
Cdd:cd19502 41 LLYGPPGTGKTLLAKAVANHTDATFIRVVGSELVQKYIGEgarlVRELFEMARE-----KAPSIIFIDEI 105
|
|
| RecA-like_ATAD1 |
cd19520 |
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ... |
259-335 |
5.86e-05 |
|
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410928 [Multi-domain] Cd Length: 166 Bit Score: 43.95 E-value: 5.86e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 254540120 259 LILWGPPGCGKTTLAHIIAnnsKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKR--KTILFIDEIHRFNKSQQDT 335
Cdd:cd19520 38 VLLYGPPGCGKTMLAKATA---KEAGARFINLQVSSLTDKWYGESQKLVAAVFSLASKlqPSIIFIDEIDSFLRQRSST 113
|
|
| RecA-like_CDC48_NLV2_r1-like |
cd19503 |
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ... |
259-325 |
6.52e-05 |
|
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410911 [Multi-domain] Cd Length: 165 Bit Score: 43.82 E-value: 6.52e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSKkhsIRFVTLSA----------TNAKtndVRDVIKQAQNEKsffkrKTILFIDEI 325
Cdd:cd19503 37 VLLHGPPGTGKTLLARAVANEAG---ANFLSISGpsivskylgeSEKN---LREIFEEARSHA-----PSIIFIDEI 102
|
|
| PRK04132 |
PRK04132 |
replication factor C small subunit; Provisional |
220-278 |
1.05e-04 |
|
replication factor C small subunit; Provisional
Pssm-ID: 235223 [Multi-domain] Cd Length: 846 Bit Score: 45.60 E-value: 1.05e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 254540120 220 KPLADKMRPDTLQDYIGQSRAVGQetlLRSLLEANEIPSLILWGPPGCGK--TTLAHIIAN 278
Cdd:PRK04132 7 KPWVEKYRPQRLDDIVGQEHIVKR---LKHYVKTGSMPHLLFAGPPGVGKclTGDTKVIAN 64
|
|
| RecA-like_PEX1_r2 |
cd19526 |
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ... |
259-324 |
1.27e-04 |
|
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410934 [Multi-domain] Cd Length: 158 Bit Score: 42.80 E-value: 1.27e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSkkhSIRFVTLSA-------TNAKTNDVRDVIKQAQNEKSffkrkTILFIDE 324
Cdd:cd19526 30 ILLYGPPGCGKTLLASAIASEC---GLNFISVKGpellnkyIGASEQNVRDLFSRAQSAKP-----CILFFDE 94
|
|
| RecA-like_CDC48_r2-like |
cd19528 |
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ... |
259-332 |
1.28e-04 |
|
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410936 [Multi-domain] Cd Length: 161 Bit Score: 42.88 E-value: 1.28e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSKKHSI-----RFVTLSATNAKTNdVRDVIKQAQNEKSffkrkTILFIDEIHRFNKSQ 332
Cdd:cd19528 30 VLFYGPPGCGKTLLAKAIANECQANFIsvkgpELLTMWFGESEAN-VRDIFDKARAAAP-----CVLFFDELDSIAKAR 102
|
|
| RecA-like_FtsH |
cd19501 |
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ... |
255-325 |
1.35e-04 |
|
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410909 [Multi-domain] Cd Length: 171 Bit Score: 42.99 E-value: 1.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 255 EIP-SLILWGPPGCGKTTLAHIIANNSKkhsIRFVTLSATN---------AKTndVRDVIKQAqneksffKRKT--ILFI 322
Cdd:cd19501 35 KIPkGVLLVGPPGTGKTLLAKAVAGEAG---VPFFSISGSDfvemfvgvgASR--VRDLFEQA-------KKNApcIVFI 102
|
...
gi 254540120 323 DEI 325
Cdd:cd19501 103 DEI 105
|
|
| PRK08451 |
PRK08451 |
DNA polymerase III subunits gamma and tau; Validated |
222-330 |
1.81e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236267 [Multi-domain] Cd Length: 535 Bit Score: 44.64 E-value: 1.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYIGQSrAVGQEtlLRSLLEANEIPSLILW-GPPGCGKTTLAHII-----------------------A 277
Cdd:PRK08451 4 LALKYRPKHFDELIGQE-SVSKT--LSLALDNNRLAHAYLFsGLRGSGKTSSARIFaralvceqgpsstpcdtciqcqsA 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 254540120 278 NNSkkHSIRFVTL-SATNAKTNDVRDVIKQAQNEKSFFKRKtILFIDEIHRFNK 330
Cdd:PRK08451 81 LEN--RHIDIIEMdAASNRGIDDIRELIEQTKYKPSMARFK-IFIIDEVHMLTK 131
|
|
| PRK14958 |
PRK14958 |
DNA polymerase III subunits gamma and tau; Provisional |
222-446 |
2.40e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 184922 [Multi-domain] Cd Length: 509 Bit Score: 44.34 E-value: 2.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYIGQSRAVgqETLLRSLLEANEIPSLILWGPPGCGKTTLAHIIA------------------NNSKKH 283
Cdd:PRK14958 6 LARKWRPRCFQEVIGQAPVV--RALSNALDQQYLHHAYLFTGTRGVGKTTISRILAkclncekgvsanpcndceNCREID 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 284 SIRFVTL----SATNAKTNDVRDVIKQAQNEKSFFKRKTILfIDEIHRFNKSQQDTFLPHVE--CGTITLIGATTENPSF 357
Cdd:PRK14958 84 EGRFPDLfevdAASRTKVEDTRELLDNIPYAPTKGRFKVYL-IDEVHMLSGHSFNALLKTLEepPSHVKFILATTDHHKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 358 QVnaALLSRCRVIVLEKLPveamvtilmrainslgihvldssrPTDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDART 437
Cdd:PRK14958 163 PV--TVLSRCLQFHLAQLP------------------------PLQIAAHCQHLLKEENVEFENAALDLLARAANGSVRD 216
|
....*....
gi 254540120 438 GLNGLQLAV 446
Cdd:PRK14958 217 ALSLLDQSI 225
|
|
| PRK12422 |
PRK12422 |
chromosomal replication initiator protein DnaA; |
261-488 |
2.81e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 183521 [Multi-domain] Cd Length: 445 Bit Score: 43.67 E-value: 2.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 261 LWGPPGCGKTTL----AHIIANNSKKhsIRFVtlsATNAKTNDVRDVIK--QAQNEKSFFKRKTILFIDEIHRFNK---S 331
Cdd:PRK12422 146 LFGPEGSGKTHLmqaaVHALRESGGK--ILYV---RSELFTEHLVSAIRsgEMQRFRQFYRNVDALFIEDIEVFSGkgaT 220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 332 QQDTFLP----HVECGTITLIGATTENPSFQVNAALLSRCR---VIVLEKLPVEAMVTILMRAINSLGIHvldssrptdp 404
Cdd:PRK12422 221 QEEFFHTfnslHTEGKLIVISSTCAPQDLKAMEERLISRFEwgiAIPLHPLTKEGLRSFLERKAEALSIR---------- 290
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 405 lshssncssepsvfIEDKAVDTLAYLSDGDARTGLNGLQLavlarLSSRKVFCKKSGQtyspsrvLITENDVKeglqrsH 484
Cdd:PRK12422 291 --------------IEETALDFLIEALSSNVKSLLHALTL-----LAKRVAYKKLSHQ-------LLYVDDIK------A 338
|
....
gi 254540120 485 ILYD 488
Cdd:PRK12422 339 LLHD 342
|
|
| clpC |
CHL00095 |
Clp protease ATP binding subunit |
260-384 |
2.93e-04 |
|
Clp protease ATP binding subunit
Pssm-ID: 214361 [Multi-domain] Cd Length: 821 Bit Score: 44.28 E-value: 2.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 260 ILWGPPGCGKTT----LAHIIANNSKK---HSIRFVTLSATN--AKTND-------VRDVIKQAQNEKsffkrKTILFID 323
Cdd:CHL00095 204 ILIGEPGVGKTAiaegLAQRIVNRDVPdilEDKLVITLDIGLllAGTKYrgefeerLKRIFDEIQENN-----NIILVID 278
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 254540120 324 EIHR-FNKSQQDT-------FLPHVECGTITLIGATTEN---PSFQVNAALLSRCRVIVLEKLPVEAMVTIL 384
Cdd:CHL00095 279 EVHTlIGAGAAEGaidaaniLKPALARGELQCIGATTLDeyrKHIEKDPALERRFQPVYVGEPSVEETIEIL 350
|
|
| RecA-like_VPS4-like |
cd19509 |
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ... |
258-366 |
3.03e-04 |
|
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410917 [Multi-domain] Cd Length: 163 Bit Score: 41.95 E-value: 3.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 258 SLILWGPPGCGKTTLAHIIANNSkkhSIRFVTLSATN-------AKTNDVRDVIKQAQneksfFKRKTILFIDEIHRFNK 330
Cdd:cd19509 34 GILLYGPPGTGKTLLARAVASES---GSTFFSISASSlvskwvgESEKIVRALFALAR-----ELQPSIIFIDEIDSLLS 105
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 254540120 331 SQQDT-----------FL------PHVECGTITLIGATteNPSFQVNAALLSR 366
Cdd:cd19509 106 ERGSGeheasrrvkteFLvqmdgvLNKPEDRVLVLGAT--NRPWELDEAFLRR 156
|
|
| PTZ00454 |
PTZ00454 |
26S protease regulatory subunit 6B-like protein; Provisional |
259-325 |
3.97e-04 |
|
26S protease regulatory subunit 6B-like protein; Provisional
Pssm-ID: 240423 [Multi-domain] Cd Length: 398 Bit Score: 43.21 E-value: 3.97e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSATNAKTND----VRDVIKQAQnEKSffkrKTILFIDEI 325
Cdd:PTZ00454 182 VLLYGPPGTGKTMLAKAVAHHTTATFIRVVGSEFVQKYLGEgprmVRDVFRLAR-ENA----PSIIFIDEV 247
|
|
| hflB |
PRK10733 |
ATP-dependent zinc metalloprotease FtsH; |
197-325 |
4.35e-04 |
|
ATP-dependent zinc metalloprotease FtsH;
Pssm-ID: 182683 [Multi-domain] Cd Length: 644 Bit Score: 43.48 E-value: 4.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 197 GVSAGRAHPRALAAEEIRQMLEGKPLADKMRPDT--LQDYIgqsRAVGQETLLrslleANEIPSLILW-GPPGCGKTTLA 273
Cdd:PRK10733 131 AMSFGKSKARMLTEDQIKTTFADVAGCDEAKEEVaeLVEYL---REPSRFQKL-----GGKIPKGVLMvGPPGTGKTLLA 202
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 254540120 274 HIIANNSKkhsIRFVTLSATN-------AKTNDVRDVIKQAQNEKSffkrkTILFIDEI 325
Cdd:PRK10733 203 KAIAGEAK---VPFFTISGSDfvemfvgVGASRVRDMFEQAKKAAP-----CIIFIDEI 253
|
|
| DEXXQc_SF1 |
cd18043 |
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are ... |
243-279 |
5.02e-04 |
|
DEXXQ-box helicase domain of Superfamily 1 helicases; Superfamily 1 (SF1) helicases are nucleic acid motor proteins that couple ATP hydrolysis to translocation along with the concomitant unwinding of DNA or RNA. This is central to many aspects of cellular DNA and RNA metabolism and accordingly, they are implicated in a wide range of nucleic acid processing events including DNA replication, recombination, and repair as well as many aspects of RNA metabolism. Superfamily 1 helicases are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350801 [Multi-domain] Cd Length: 127 Bit Score: 40.26 E-value: 5.02e-04
10 20 30
....*....|....*....|....*....|....*...
gi 254540120 243 QETLLRSLLEAneiPSLILWGPPGCGKT-TLAHIIANN 279
Cdd:cd18043 4 QEAAIISARNG---KNVVIQGPPGTGKSqTIANIIANA 38
|
|
| Bac_DnaA |
pfam00308 |
Bacterial dnaA protein; |
259-333 |
6.20e-04 |
|
Bacterial dnaA protein;
Pssm-ID: 278724 [Multi-domain] Cd Length: 219 Bit Score: 41.54 E-value: 6.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 259 LILWGPPGCGKTTLAHIIANN--SKKHSIRFVTLSATNAkTNDVRDVIKqaQNEKSFFKRK----TILFIDEIHRFNKSQ 332
Cdd:pfam00308 37 LFIYGGVGLGKTHLLHAIGNYalQNAPNLRVVYLTAEEF-LNDFVDAIR--DNKTNQFKEKyrnvDVLLIDDIQFLAGKE 113
|
.
gi 254540120 333 Q 333
Cdd:pfam00308 114 G 114
|
|
| RAD18 |
COG5432 |
RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]; |
18-83 |
8.30e-04 |
|
RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms];
Pssm-ID: 227719 [Multi-domain] Cd Length: 391 Bit Score: 42.38 E-value: 8.30e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 254540120 18 VQCPVCQQMMPAAHINSHLDRCLLLH--PAGHAEP---AAGSH-RAGERAKGPSPPGAKRRRLSESSALKQP 83
Cdd:COG5432 161 VHCPACSNLVPHNQINQHLDSCLNSPssPSSSSSPyknKDNSKsNSLLSFKTDDDSITKRRLRSFNSADELP 232
|
|
| RecA-like_NVL_r2-like |
cd19530 |
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ... |
259-285 |
1.03e-03 |
|
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410938 [Multi-domain] Cd Length: 161 Bit Score: 40.16 E-value: 1.03e-03
10 20
....*....|....*....|....*..
gi 254540120 259 LILWGPPGCGKTTLAHIIANNSKKHSI 285
Cdd:cd19530 33 VLLYGPPGCGKTLLAKAVANESGANFI 59
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
258-328 |
2.13e-03 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 38.86 E-value: 2.13e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 258 SLILWGPPGCGKTTLAHIIANNSKKHSIR--FVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILF-------------- 321
Cdd:pfam13401 7 ILVLTGESGTGKTTLLRRLLEQLPEVRDSvvFVDLPSGTSPKDLLRALLRALGLPLSGRLSKEELLaalqqlllalavav 86
|
90
....*....|
gi 254540120 322 ---IDEIHRF 328
Cdd:pfam13401 87 vliIDEAQHL 96
|
|
| ATP-synt_ab |
pfam00006 |
ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP ... |
263-322 |
2.46e-03 |
|
ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.
Pssm-ID: 425417 [Multi-domain] Cd Length: 212 Bit Score: 39.65 E-value: 2.46e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 263 GPPGCGKTTLAHIIANNSKKHSIRFVtlsATNAKTNDVRDVIKQAQNEKSFfkRKTILFI 322
Cdd:pfam00006 21 GGSGVGKTVLAGMIARQASADVVVYA---LIGERGREVREFIEELLGSGAL--KRTVVVV 75
|
|
| AAA_7 |
pfam12775 |
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 ... |
246-326 |
2.60e-03 |
|
P-loop containing dynein motor region; This domain is found in human cytoplasmic dynein-2 proteins. Cytoplasmic dynein-2 (dynein-2) performs intraflagellar transport and is associated with human skeletal ciliopathies. Dyneins share a conserved motor domain that couples cycles of ATP hydrolysis with conformational changes to produce movement. Structural analysis reveal that the motor's ring consists of six AAA+ domains (ATPases associated with various cellular activities (AAA1-AAA6). This is the third nucleotide binding sites in the dynein motor. However, AAA3 has lost the catalytic residues necessary for ATP hydrolysis (the Walker B glutamate, the arginine finger, sensor-I and sensor-II motifs).
Pssm-ID: 463698 [Multi-domain] Cd Length: 179 Bit Score: 39.30 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 246 LLRSLLEANeIPSLiLWGPPGCGKTTlahIIAN-----NSKKHSIRFVTLSA-TNAktNDVRDVIkqaqnEKSFFKR--- 316
Cdd:pfam12775 23 LLDLLLKNG-KPVL-LVGPTGTGKTV---IIQNllrklDKEKYLPLFINFSAqTTS--NQTQDII-----ESKLEKRrkg 90
|
90
....*....|....*...
gi 254540120 317 --------KTILFIDEIH 326
Cdd:pfam12775 91 vygppggkKLVVFIDDLN 108
|
|
| PTZ00361 |
PTZ00361 |
26 proteosome regulatory subunit 4-like protein; Provisional |
221-325 |
3.23e-03 |
|
26 proteosome regulatory subunit 4-like protein; Provisional
Pssm-ID: 185575 [Multi-domain] Cd Length: 438 Bit Score: 40.52 E-value: 3.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 221 PLADKMRPDT--LQDY--IGqsravGQETLLRSLLEANEIP----------------SLILWGPPGCGKTTLAHIIANNS 280
Cdd:PTZ00361 167 PLVSVMKVDKapLESYadIG-----GLEQQIQEIKEAVELPlthpelyddigikppkGVILYGPPGTGKTLLAKAVANET 241
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 254540120 281 KKHSIRFVTLSATNAKTND----VRDVIKQAQNEKSffkrkTILFIDEI 325
Cdd:PTZ00361 242 SATFLRVVGSELIQKYLGDgpklVRELFRVAEENAP-----SIVFIDEI 285
|
|
| PRK09111 |
PRK09111 |
DNA polymerase III subunits gamma and tau; Validated |
222-386 |
3.24e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236382 [Multi-domain] Cd Length: 598 Bit Score: 40.66 E-value: 3.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYIGQsravgqETLLRSL---LEANEIP-SLILWGPPGCGKTTLAHIIA---NN-----SKKHSIRFVT 289
Cdd:PRK09111 14 LARKYRPQTFDDLIGQ------EAMVRTLtnaFETGRIAqAFMLTGVRGVGKTTTARILAralNYegpdgDGGPTIDLCG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 290 L-------------------SATNAKTNDVRDVIKQAQneksfFK----RKTILFIDEIHRFNKSQQDTFL-------PH 339
Cdd:PRK09111 88 VgehcqaimegrhvdvlemdAASHTGVDDIREIIESVR-----YRpvsaRYKVYIIDEVHMLSTAAFNALLktleeppPH 162
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 254540120 340 VecgtiTLIGATTEnpSFQVNAALLSRCRVIVLEKLPVEAMVTILMR 386
Cdd:PRK09111 163 V-----KFIFATTE--IRKVPVTVLSRCQRFDLRRIEADVLAAHLSR 202
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
226-386 |
3.33e-03 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 40.15 E-value: 3.33e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 226 MRPDTLQDYIGQsRAVGQETLLRSLLEA--NEIPsLILWGPPGCGKTTLAHIIANNSKKHSIR--FvtlsatnakTNDVR 301
Cdd:COG0714 1 MTEARLRAEIGK-VYVGQEELIELVLIAllAGGH-LLLEGVPGVGKTTLAKALARALGLPFIRiqF---------TPDLL 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 302 --DV----IKQAQNEKSFFKR----KTILFIDEIhrfNKSQQDT--FLPHV-ECGTITLIGAT-----------TENPSF 357
Cdd:COG0714 70 psDIlgtyIYDQQTGEFEFRPgplfANVLLADEI---NRAPPKTqsALLEAmEERQVTIPGGTyklpepflviaTQNPIE 146
|
170 180 190
....*....|....*....|....*....|....*
gi 254540120 358 QVN-----AALLSRCRV-IVLEKLPVEAMVTILMR 386
Cdd:COG0714 147 QEGtyplpEAQLDRFLLkLYIGYPDAEEEREILRR 181
|
|
| RNA_helicase |
pfam00910 |
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ... |
259-278 |
3.38e-03 |
|
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.
Pssm-ID: 459992 Cd Length: 102 Bit Score: 37.58 E-value: 3.38e-03
|
| AAA_16 |
pfam13191 |
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the ... |
241-289 |
3.71e-03 |
|
AAA ATPase domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.
Pssm-ID: 433025 [Multi-domain] Cd Length: 167 Bit Score: 38.64 E-value: 3.71e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 254540120 241 VGQETLLRSLLEA------NEIPSLILWGPPGCGKTTLAHIIANNSKKHSIRFVT 289
Cdd:pfam13191 3 VGREEELEQLLDAldrvrsGRPPSVLLTGEAGTGKTTLLRELLRALERDGGYFLR 57
|
|
| PRK14952 |
PRK14952 |
DNA polymerase III subunits gamma/tau; |
222-401 |
3.84e-03 |
|
DNA polymerase III subunits gamma/tau;
Pssm-ID: 237866 [Multi-domain] Cd Length: 584 Bit Score: 40.25 E-value: 3.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 222 LADKMRPDTLQDYIGQSRAVGqetLLRSLLEANEIPSLILW-GPPGCGKTTLAHIIANN--------------------- 279
Cdd:PRK14952 3 LYRKYRPATFAEVVGQEHVTE---PLSSALDAGRINHAYLFsGPRGCGKTSSARILARSlncaqgptatpcgvcescval 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 280 --SKKHSIRFVTLSAtnAKTNDVRDVikQAQNEKSFF----KRKTILFIDEIHRFNKSQQDTFLPHVE--CGTITLIGAT 351
Cdd:PRK14952 80 apNGPGSIDVVELDA--ASHGGVDDT--RELRDRAFYapaqSRYRIFIVDEAHMVTTAGFNALLKIVEepPEHLIFIFAT 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 254540120 352 TEnPSfQVNAALLSRCRVIVLEKLPVEAMVTILMRAINSLGIHVLDSSRP 401
Cdd:PRK14952 156 TE-PE-KVLPTIRSRTHHYPFRLLPPRTMRALIARICEQEGVVVDDAVYP 203
|
|
| PRK08903 |
PRK08903 |
DnaA regulatory inactivator Hda; Validated |
228-333 |
4.07e-03 |
|
DnaA regulatory inactivator Hda; Validated
Pssm-ID: 236347 [Multi-domain] Cd Length: 227 Bit Score: 39.19 E-value: 4.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 228 PDTLQDYIGQSRAvgqETL--LRSLLEANEI-PSLILWGPPGCGKTTLAHIIANNSKKHSIRFVTLSAtnaktndvrdvi 304
Cdd:PRK08903 14 PPTFDNFVAGENA---ELVarLRELAAGPVAdRFFYLWGEAGSGRSHLLQALVADASYGGRNARYLDA------------ 78
|
90 100
....*....|....*....|....*....
gi 254540120 305 KQAQNEKSFFKRKTILFIDEIHRFNKSQQ 333
Cdd:PRK08903 79 ASPLLAFDFDPEAELYAVDDVERLDDAQQ 107
|
|
| T7SS_EccA |
TIGR03922 |
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ... |
187-278 |
5.70e-03 |
|
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 188437 [Multi-domain] Cd Length: 557 Bit Score: 39.83 E-value: 5.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 187 WDADAADASFGVSAGRAHPRAlaaeeIRQMLEGKPLADKMrpdtlqdyIGQSRAVGQETLLRSLLEANEIPS-------- 258
Cdd:TIGR03922 244 WDPSSAPSRAEFVDPAAAERK-----AKLLAEAEAELAEQ--------IGLERVKRQVAALKSSTAMALARAerglpvaq 310
|
90 100
....*....|....*....|....
gi 254540120 259 ----LILWGPPGCGKTTLAHIIAN 278
Cdd:TIGR03922 311 tsnhMLFAGPPGTGKTTIARVVAK 334
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
259-349 |
7.15e-03 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 36.83 E-value: 7.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 259 LILWGPPGCGKT-TLAHIIANNSKKHSIRFVTLSATnakTNDVRDVIkqaqneksffkrkTILFIDEIhrfnkSQQ---D 334
Cdd:cd17934 2 SLIQGPPGTGKTtTIAAIVLQLLKGLRGKRVLVTAQ---SNVAVDNV-------------DVVIIDEA-----SQItepE 60
|
90
....*....|....*
gi 254540120 335 TFLPHVECGTITLIG 349
Cdd:cd17934 61 LLIALIRAKKVVLVG 75
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
251-277 |
7.95e-03 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 38.22 E-value: 7.95e-03
10 20
....*....|....*....|....*..
gi 254540120 251 LEANEIPSLIlwGPPGCGKTTLAHIIA 277
Cdd:cd03293 27 VEEGEFVALV--GPSGCGKSTLLRIIA 51
|
|
| AAA_2 |
pfam07724 |
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ... |
255-346 |
9.84e-03 |
|
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400187 [Multi-domain] Cd Length: 168 Bit Score: 37.56 E-value: 9.84e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 254540120 255 EIPSLILWGPPGCGKTTLAHIIAN---NSKKHSIRFVTLSATNAKTNDvRDVIKQ------AQN----EKSFFKRKTILF 321
Cdd:pfam07724 2 PIGSFLFLGPTGVGKTELAKALAEllfGDERALIRIDMSEYMEEHSVS-RLIGAPpgyvgyEEGgqltEAVRRKPYSIVL 80
|
90 100
....*....|....*....|....*
gi 254540120 322 IDEIHRFNKSQQDTFLPHVECGTIT 346
Cdd:pfam07724 81 IDEIEKAHPGVQNDLLQILEGGTLT 105
|
|
| |
