NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|15221268|ref|NP_172068|]
View 

Mannose-binding lectin superfamily protein [Arabidopsis thaliana]

Protein Classification

jacalin family lectin; zinc metalloproteinase family protein( domain architecture ID 10658524)

jacalin family lectin is a sugar-binding protein containing a jacalin domain| zinc metalloproteinase family protein contains an HEXXH motif characteristic of metallopeptidases; contains a Jacalin-like lectin domain that may bind mono- or oligosaccharides

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
23-163 4.72e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


:

Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 106.93  E-value: 4.72e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268     23 WDEGSHNGIiSQIFLSHGPTGVFSIQFQFMlDDTFFLSSCHGQNTGSMFDVilLNCPHEYITGISGEYLKSDGasgpqIR 102
Cdd:smart00915   4 WDDGAFDGV-RKIYVGQGGEGIKSIQFDYD-KGGKVWGDEHGGKGGTGEEI--LLYPGEYITSVEGTYDKSGV-----IT 74
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15221268    103 SLAFATNLNQYGPFGGSSSQSSiwnheqqFRFKLGKFRQFSGFYGTYNASGLQNIGVYLQP 163
Cdd:smart00915  75 SLTFKTNKGRTSPFGGYEGGTK-------FVLESKEGKKIVGFHGRSSGDGLDSLGAYFSP 128
 
Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
23-163 4.72e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 106.93  E-value: 4.72e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268     23 WDEGSHNGIiSQIFLSHGPTGVFSIQFQFMlDDTFFLSSCHGQNTGSMFDVilLNCPHEYITGISGEYLKSDGasgpqIR 102
Cdd:smart00915   4 WDDGAFDGV-RKIYVGQGGEGIKSIQFDYD-KGGKVWGDEHGGKGGTGEEI--LLYPGEYITSVEGTYDKSGV-----IT 74
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15221268    103 SLAFATNLNQYGPFGGSSSQSSiwnheqqFRFKLGKFRQFSGFYGTYNASGLQNIGVYLQP 163
Cdd:smart00915  75 SLTFKTNKGRTSPFGGYEGGTK-------FVLESKEGKKIVGFHGRSSGDGLDSLGAYFSP 128
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
23-162 5.31e-20

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 81.07  E-value: 5.31e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268  23 WDEGSHNGIISQIFLSHGPTGVFSIQFQFMLDDTFFLSSCHGqNTGSMFDVILLNCPHEYITGISGEYLKSDGASGpqIR 102
Cdd:cd09612   4 WDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHG-GGGGTPEEIVLDYPDEYITSVSGTYGPVSGSNV--IT 80
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268 103 SLAFATNLNQYGPFGGSSSQSsiwnheqqFRFKLGKFRqFSGFYGTYnASGLQNIGVYLQ 162
Cdd:cd09612  81 SLTFKTNKRTYGPFGVESGTP--------FSLPVEGGK-IVGFHGRS-GDYLDAIGVYVS 130
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
23-163 5.74e-14

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 65.38  E-value: 5.74e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268    23 WDEGSHNGIiSQIFLSHGPTGVFSIQFQFMLDDTFFLSSCHGQNTGSMFDVILLNCPHEYITGISGEYLKSDGASGPQIR 102
Cdd:pfam01419   4 WDDGVYDGV-RKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEVIT 82
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15221268   103 SLAFATNLNQYGPFGGsssqssiwnHEQQFRFKL-GKFRQFSGFYGTYNASgLQNIGVYLQP 163
Cdd:pfam01419  83 SLTFKTNKGRTSPFFG---------TPSGTKFSLeVKGKKIVGFHGRAGNA-LNALGAYFAP 134
 
Name Accession Description Interval E-value
Jacalin smart00915
Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a ...
23-163 4.72e-30

Jacalin-like lectin domain; This entry represents a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B- cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein.


Pssm-ID: 214909 [Multi-domain]  Cd Length: 128  Bit Score: 106.93  E-value: 4.72e-30
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268     23 WDEGSHNGIiSQIFLSHGPTGVFSIQFQFMlDDTFFLSSCHGQNTGSMFDVilLNCPHEYITGISGEYLKSDGasgpqIR 102
Cdd:smart00915   4 WDDGAFDGV-RKIYVGQGGEGIKSIQFDYD-KGGKVWGDEHGGKGGTGEEI--LLYPGEYITSVEGTYDKSGV-----IT 74
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15221268    103 SLAFATNLNQYGPFGGSSSQSSiwnheqqFRFKLGKFRQFSGFYGTYNASGLQNIGVYLQP 163
Cdd:smart00915  75 SLTFKTNKGRTSPFGGYEGGTK-------FVLESKEGKKIVGFHGRSSGDGLDSLGAYFSP 128
Jacalin cd09612
Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains ...
23-162 5.31e-20

Jacalin-like plant lectin domain; Jacalin-like lectins are sugar-binding protein domains mostly found in plants. They adopt a beta-prism topology consistent with a circularly permuted three-fold repeat of a structural motif. Proteins containing this domain may bind mono- or oligosaccharides with high specificity. The domain can occur in tandem-repeat arrangements with up to six copies, and in architectures combined with a variety of other functional domains. The family was initially named after an abundant protein found in the jackfruit seed. Jacalin specifically binds to the alpha-O-glycoside of the disaccharide Gal-beta1-3-GalNAc, and has proven useful in the study of O-linked glycoproteins. Jacalin-like lectins in this family may occur in various oligomerization states.


Pssm-ID: 187708 [Multi-domain]  Cd Length: 130  Bit Score: 81.07  E-value: 5.31e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268  23 WDEGSHNGIISQIFLSHGPTGVFSIQFQFMLDDTFFLSSCHGqNTGSMFDVILLNCPHEYITGISGEYLKSDGASGpqIR 102
Cdd:cd09612   4 WDDGVFPDGLRKITVRSGENGIDSIKFEYDKDGQHVVGPWHG-GGGGTPEEIVLDYPDEYITSVSGTYGPVSGSNV--IT 80
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268 103 SLAFATNLNQYGPFGGSSSQSsiwnheqqFRFKLGKFRqFSGFYGTYnASGLQNIGVYLQ 162
Cdd:cd09612  81 SLTFKTNKRTYGPFGVESGTP--------FSLPVEGGK-IVGFHGRS-GDYLDAIGVYVS 130
Jacalin pfam01419
Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 ...
23-163 5.74e-14

Jacalin-like lectin domain; Proteins containing this domain are lectins. It is found in 1 to 6 copies in these proteins. The domain is also found in the animal prostatic spermine-binding protein.


Pssm-ID: 396138 [Multi-domain]  Cd Length: 134  Bit Score: 65.38  E-value: 5.74e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15221268    23 WDEGSHNGIiSQIFLSHGPTGVFSIQFQFMLDDTFFLSSCHGQNTGSMFDVILLNCPHEYITGISGEYLKSDGASGPQIR 102
Cdd:pfam01419   4 WDDGVYDGV-RKVYVGQGGDGITYIKFEYVKGGGKVEGDEHGKKGLLGPEEFEIDYPDEYITSVEGTYDKVFGSDSEVIT 82
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15221268   103 SLAFATNLNQYGPFGGsssqssiwnHEQQFRFKL-GKFRQFSGFYGTYNASgLQNIGVYLQP 163
Cdd:pfam01419  83 SLTFKTNKGRTSPFFG---------TPSGTKFSLeVKGKKIVGFHGRAGNA-LNALGAYFAP 134
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH