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Conserved domains on  [gi|15218573|ref|NP_174689|]
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receptor like protein 5 [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR super family cl34836
Leucine-rich repeat (LRR) protein [Transcription];
81-130 8.25e-09

Leucine-rich repeat (LRR) protein [Transcription];


The actual alignment was detected with superfamily member COG4886:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 55.71  E-value: 8.25e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15218573  81 NLIGTISPHFADLTSLRVIDLSHNRLKcTIPFEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 192 NQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQL 240
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-130 8.25e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 55.71  E-value: 8.25e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15218573  81 NLIGTISPHFADLTSLRVIDLSHNRLKcTIPFEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 192 NQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQL 240
PLN03150 PLN03150
hypothetical protein; Provisional
 81-135 1.36e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.13  E-value: 1.36e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15218573   81 NLIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN03150 453 SIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
LRR_8 pfam13855
Leucine rich repeat;
81-130 6.47e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 6.47e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 15218573    81 NLIGTISPH-FADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQL 130
Cdd:pfam13855  11 NRLTSLDDGaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 95-131 8.69e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 36.69  E-value: 8.69e-03
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 15218573  95 SLRVIDLSHNRLKCTIPFEitKLKNLTIVDVSYNQLH 131
Cdd:cd21340 121 SLRVLNISGNNIDSLEPLA--PLRNLEQLDASNNQIS 155
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-130 8.25e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 55.71  E-value: 8.25e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15218573  81 NLIGTISPHFADLTSLRVIDLSHNRLKcTIPFEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 192 NQITDLPEPLGNLTNLEELDLSGNQLT-DLPEPLANLTNLETLDLSNNQL 240
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-130 3.29e-08

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 53.78  E-value: 3.29e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15218573  81 NLIGTISPHFADLTSLRVIDLSHNRLKcTIPFEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 169 NQLTDLPEELGNLTNLKELDLSNNQIT-DLPEPLGNLTNLEELDLSGNQL 217
PLN03150 PLN03150
hypothetical protein; Provisional
 81-135 1.36e-07

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 52.13  E-value: 1.36e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15218573   81 NLIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN03150 453 SIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSGRVP 507
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-130 2.97e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 51.09  E-value: 2.97e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15218573  81 NLIGTISPHFADLTSLRVIDLSHNRLKcTIPFEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 146 NQLTDLPEPLGNLTNLKSLDLSNNQLT-DLPEELGNLTNLKELDLSNNQI 194
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-130 3.00e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 50.70  E-value: 3.00e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15218573  81 NLIGTISPHFADLTSLRVIDLSHNRLKcTIPFEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 123 NQLTDLPEELANLTNLKELDLSNNQLT-DLPEPLGNLTNLKSLDLSNNQL 171
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-130 4.40e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 50.32  E-value: 4.40e-07
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15218573  81 NLIGTISPHFADLTSLRVIDLSHNRLKcTIPfEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 215 NQLTDLPEPLANLTNLETLDLSNNQLT-DLP-ELGNLTNLEELDLSNNQL 262
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 82-135 1.92e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 48.69  E-value: 1.92e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 15218573   82 LIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN00113 176 LVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYNNLSGEIP 229
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 81-135 3.95e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 47.92  E-value: 3.95e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15218573   81 NLIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN00113 247 NLTGPIPSSLGNLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIP 301
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
80-130 4.04e-06

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 47.62  E-value: 4.04e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|.
gi 15218573  80 LNLIGTisPHFADLTSLRVIDLSHNRLKcTIPFEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 101 LDLSGN--EELSNLTNLESLDLSGNQLT-DLPEELANLTNLKELDLSNNQL 148
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 81-135 4.73e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 47.54  E-value: 4.73e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15218573   81 NLIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN00113 534 QLSGQIPASFSEMPVLSQLDLSQNQLSGEIPKNLGNVESLVQVNISHNHLHGSLP 588
LRR_8 pfam13855
Leucine rich repeat;
81-130 6.47e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 6.47e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 15218573    81 NLIGTISPH-FADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQL 130
Cdd:pfam13855  11 NRLTSLDDGaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 46-136 3.41e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 44.84  E-value: 3.41e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218573   46 DPEEFVTSWQGNNP-CEWFGTNCLEGIIIGISFIS-LNLIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKL-KNLTI 122
Cdd:PLN00113  43 DPLKYLSNWNSSADvCLWQGITCNNSSRVVSIDLSgKNISGKISSAIFRLPYIQTINLSNNQLSGPIPDDIFTTsSSLRY 122

                         90
                 ....*....|....
gi 15218573  123 VDVSYNQLHGEVPR 136
Cdd:PLN00113 123 LNLSNNNFTGSIPR 136
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 81-135 3.98e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 44.84  E-value: 3.98e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15218573   81 NLIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN00113 319 NFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKHNNLTVLDLSTNNLTGEIP 373
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 84-135 4.39e-05

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 44.45  E-value: 4.39e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|..
gi 15218573   84 GTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN00113 489 GAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIP 540
PLN03150 PLN03150
hypothetical protein; Provisional
 54-139 5.39e-05

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 44.04  E-value: 5.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15218573   54 WQGNnPC-----EWFGTNC-LEGIIIGISFISLNL-----IGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTI 122
Cdd:PLN03150 392 WNGD-PCvpqqhPWSGADCqFDSTKGKWFIDGLGLdnqglRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEV 470

                         90
                 ....*....|....*..
gi 15218573  123 VDVSYNQLHGEVPRVRG 139
Cdd:PLN03150 471 LDLSYNSFNGSIPESLG 487
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
81-130 1.55e-04

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 42.61  E-value: 1.55e-04
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 15218573  81 NLIGTIsPHFADLTSLRVIDLSHNRLKcTIPfEITKLKNLTIVDVSYNQL 130
Cdd:COG4886 238 NQLTDL-PELGNLTNLEELDLSNNQLT-DLP-PLANLTNLKTLDLSNNQL 284
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 82-135 3.00e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.14  E-value: 3.00e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 15218573   82 LIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN00113 200 LVGQIPRELGQMKSLKWIYLGYNNLSGEIPYEIGGLTSLNHLDLVYNNLTGPIP 253
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 82-135 3.85e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 41.76  E-value: 3.85e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 15218573   82 LIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVP 135
Cdd:PLN00113 511 LSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPVLSQLDLSQNQLSGEIP 564
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 82-136 9.98e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.22  E-value: 9.98e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 15218573   82 LIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVPR 136
Cdd:PLN00113 272 LSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTGKIPV 326
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 82-139 1.07e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.22  E-value: 1.07e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 15218573   82 LIGTISPHFADLTSLRVIDLSHNRLKCTIPFEITKLKNLTIVDVSYNQLHGEVPRVRG 139
Cdd:PLN00113 152 LSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELG 209
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 81-136 2.70e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 39.06  E-value: 2.70e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 15218573   81 NLIGTISPHFADLTSLRVIDLSHNRLKCTIP--FEITKLKNLtivDVSYNQLHGEVPR 136
Cdd:PLN00113 439 NLQGRINSRKWDMPSLQMLSLARNKFFGGLPdsFGSKRLENL---DLSRNQFSGAVPR 493
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 95-131 8.69e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 36.69  E-value: 8.69e-03
                        10        20        30
                ....*....|....*....|....*....|....*..
gi 15218573  95 SLRVIDLSHNRLKCTIPFEitKLKNLTIVDVSYNQLH 131
Cdd:cd21340 121 SLRVLNISGNNIDSLEPLA--PLRNLEQLDASNNQIS 155
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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