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Conserved domains on  [gi|15230155|ref|NP_188495|]
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AGAMOUS-like 103 [Arabidopsis thaliana]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
18-100 1.61e-22

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


:

Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 90.40  E-value: 1.61e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15230155  18 KTFFKKPNSAFSSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGELKTWPEEREkVKAIARRYGELSETKRRKG 97
Cdd:cd00266   2 RKKIKIKRIENKKKRAVTFSKRRQGLFKKASELSTLCGAEVAVIVYSPSGKLYVFWPSSE-VEGVISRFEVLSALERKKK 80

                ...
gi 15230155  98 SVD 100
Cdd:cd00266  81 AVD 83
DUF4252 super family cl20504
Domain of unknown function (DUF4252); This family of proteins is functionally uncharacterized. ...
245-304 6.55e-03

Domain of unknown function (DUF4252); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 154 and 182 amino acids in length.


The actual alignment was detected with superfamily member pfam14060:

Pssm-ID: 433684  Cd Length: 123  Bit Score: 36.43  E-value: 6.55e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15230155   245 AGNYSGSLGVQGTGINGLQNMNMLTYNNINSVNDFSKQFDQ-NSRAESYSSLLGVHEDGNN 304
Cdd:pfam14060  20 ASKFLDDDNELKELLKKLKSIKVLSTEKNSSAADLKKEFKKlLSKKNKYEELMRVKDKGEK 80
 
Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
18-100 1.61e-22

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 90.40  E-value: 1.61e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15230155  18 KTFFKKPNSAFSSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGELKTWPEEREkVKAIARRYGELSETKRRKG 97
Cdd:cd00266   2 RKKIKIKRIENKKKRAVTFSKRRQGLFKKASELSTLCGAEVAVIVYSPSGKLYVFWPSSE-VEGVISRFEVLSALERKKK 80

                ...
gi 15230155  98 SVD 100
Cdd:cd00266  81 AVD 83
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
29-72 1.93e-15

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 69.76  E-value: 1.93e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 15230155    29 SSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGELKTW 72
Cdd:pfam00319   5 KRARQVTFSKRRKGLFKKASELSVLCGAEVAVIVFSPTGKLYTF 48
MADS smart00432
MADS domain;
29-69 8.31e-13

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 62.57  E-value: 8.31e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 15230155     29 SSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGEL 69
Cdd:smart00432  13 KTNRQVTFSKRRNGLFKKAHELSVLCDAEVALIVFSPTGKL 53
DUF4252 pfam14060
Domain of unknown function (DUF4252); This family of proteins is functionally uncharacterized. ...
245-304 6.55e-03

Domain of unknown function (DUF4252); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 154 and 182 amino acids in length.


Pssm-ID: 433684  Cd Length: 123  Bit Score: 36.43  E-value: 6.55e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15230155   245 AGNYSGSLGVQGTGINGLQNMNMLTYNNINSVNDFSKQFDQ-NSRAESYSSLLGVHEDGNN 304
Cdd:pfam14060  20 ASKFLDDDNELKELLKKLKSIKVLSTEKNSSAADLKKEFKKlLSKKNKYEELMRVKDKGEK 80
 
Name Accession Description Interval E-value
MADS_SRF_like cd00266
SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) ...
18-100 1.61e-22

SRF-like/Type I subfamily of MADS (MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero- and homo-dimers. Differs from the MEF-like/Type II subgroup mainly in position of the alpha 2 helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238166 [Multi-domain]  Cd Length: 83  Bit Score: 90.40  E-value: 1.61e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15230155  18 KTFFKKPNSAFSSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGELKTWPEEREkVKAIARRYGELSETKRRKG 97
Cdd:cd00266   2 RKKIKIKRIENKKKRAVTFSKRRQGLFKKASELSTLCGAEVAVIVYSPSGKLYVFWPSSE-VEGVISRFEVLSALERKKK 80

                ...
gi 15230155  98 SVD 100
Cdd:cd00266  81 AVD 83
MADS cd00120
MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic ...
18-73 1.20e-17

MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238067 [Multi-domain]  Cd Length: 59  Bit Score: 76.01  E-value: 1.20e-17
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 15230155  18 KTFFKKPNSAFSSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGELKTWP 73
Cdd:cd00120   2 RGKIEIKRIENKTSRQVTFSKRRNGLFKKASELSVLCDAEVAVIVFSPSGKLYEFW 57
SRF-TF pfam00319
SRF-type transcription factor (DNA-binding and dimerization domain);
29-72 1.93e-15

SRF-type transcription factor (DNA-binding and dimerization domain);


Pssm-ID: 459760 [Multi-domain]  Cd Length: 48  Bit Score: 69.76  E-value: 1.93e-15
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 15230155    29 SSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGELKTW 72
Cdd:pfam00319   5 KRARQVTFSKRRKGLFKKASELSVLCGAEVAVIVFSPTGKLYTF 48
MADS smart00432
MADS domain;
29-69 8.31e-13

MADS domain;


Pssm-ID: 197721 [Multi-domain]  Cd Length: 59  Bit Score: 62.57  E-value: 8.31e-13
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 15230155     29 SSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGEL 69
Cdd:smart00432  13 KTNRQVTFSKRRNGLFKKAHELSVLCDAEVALIVFSPTGKL 53
MADS_MEF2_like cd00265
MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, ...
29-69 8.39e-08

MEF2 (myocyte enhancer factor 2)-like/Type II subfamily of MADS ( MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptional regulators. Binds DNA and exists as hetero and homo-dimers. Differs from SRF-like/Type I subgroup mainly in position of the alpha helix responsible for the dimerization interface. Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.


Pssm-ID: 238165 [Multi-domain]  Cd Length: 77  Bit Score: 49.09  E-value: 8.39e-08
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 15230155  29 SSSRATSLIKRQQTVFKKAKELSILCDIDVCVICYGSNGEL 69
Cdd:cd00265  13 STNRQVTFSKRRNGLLKKAHELSVLCDAEVALIIFSSSGKL 53
DUF4252 pfam14060
Domain of unknown function (DUF4252); This family of proteins is functionally uncharacterized. ...
245-304 6.55e-03

Domain of unknown function (DUF4252); This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 154 and 182 amino acids in length.


Pssm-ID: 433684  Cd Length: 123  Bit Score: 36.43  E-value: 6.55e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15230155   245 AGNYSGSLGVQGTGINGLQNMNMLTYNNINSVNDFSKQFDQ-NSRAESYSSLLGVHEDGNN 304
Cdd:pfam14060  20 ASKFLDDDNELKELLKKLKSIKVLSTEKNSSAADLKKEFKKlLSKKNKYEELMRVKDKGEK 80
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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