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Conserved domains on  [gi|15234891|ref|NP_192741|]
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alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 11426811)

alpha/beta hydrolase family protein catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

PubMed:  1409539|12369917

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 104-371 8.47e-21

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


:

Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 89.68  E-value: 8.47e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 104 PDTPTAVLLHGILGSGKNWGTFARRLAHEFptwQFLLVDLRCHGDSTslKKRGPHSVATTASDVLKLVGQLRLTPRVLVG 183
Cdd:COG0596  21 PDGPPVVLLHGLPGSSYEWRPLIPALAAGY---RVIAPDLRGHGRSD--KPAGGYTLDDLADDLAALLDALGLERVVLVG 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 184 HSFGGKVVLSMVEQAakplPRPVRAWVLdatpgkvraggdgedhprelisflrklpkvvlskrevlkalinegfSNDVAQ 263
Cdd:COG0596  96 HSMGGMVALELAARH----PERVAGLVL----------------------------------------------VDEVLA 125

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 264 WVITNLRPTGpsassfswtFDLDGIAELYQSYEETNLWNFVENLPRGVHVnfLKAERSlhrwaleDLQRIHAAEELAsEE 343
Cdd:COG0596 126 ALAEPLRRPG---------LAPEALAALLRALARTDLRERLARITVPTLV--IWGEKD-------PIVPPALARRLA-EL 186

                       250       260
                ....*....|....*....|....*...
gi 15234891 344 GGGVEMHVLEDAGHWVHTDNPDGLFRIL 371
Cdd:COG0596 187 LPNAELVVLPGAGHFPPLEQPEAFAAAL 214
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 104-371 8.47e-21

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 89.68  E-value: 8.47e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 104 PDTPTAVLLHGILGSGKNWGTFARRLAHEFptwQFLLVDLRCHGDSTslKKRGPHSVATTASDVLKLVGQLRLTPRVLVG 183
Cdd:COG0596  21 PDGPPVVLLHGLPGSSYEWRPLIPALAAGY---RVIAPDLRGHGRSD--KPAGGYTLDDLADDLAALLDALGLERVVLVG 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 184 HSFGGKVVLSMVEQAakplPRPVRAWVLdatpgkvraggdgedhprelisflrklpkvvlskrevlkalinegfSNDVAQ 263
Cdd:COG0596  96 HSMGGMVALELAARH----PERVAGLVL----------------------------------------------VDEVLA 125

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 264 WVITNLRPTGpsassfswtFDLDGIAELYQSYEETNLWNFVENLPRGVHVnfLKAERSlhrwaleDLQRIHAAEELAsEE 343
Cdd:COG0596 126 ALAEPLRRPG---------LAPEALAALLRALARTDLRERLARITVPTLV--IWGEKD-------PIVPPALARRLA-EL 186

                       250       260
                ....*....|....*....|....*...
gi 15234891 344 GGGVEMHVLEDAGHWVHTDNPDGLFRIL 371
Cdd:COG0596 187 LPNAELVVLPGAGHFPPLEQPEAFAAAL 214
PRK10673 PRK10673
esterase;
96-369 6.99e-15

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 73.61  E-value: 6.99e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   96 RWKDDKSVPDTPTAVLLHGILGSGKNWGTFARRLAHEFPTWQfllVDLRCHGdstsLKKRGPH-SVATTASDVLKLVGQL 174
Cdd:PRK10673   6 RAQTAQNPHNNSPIVLVHGLFGSLDNLGVLARDLVNDHDIIQ---VDMRNHG----LSPRDPVmNYPAMAQDLLDTLDAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891  175 RLTPRVLVGHSFGGKVVLSMVEQAAKPLPRPVrawVLDATP--GKVRaggdgedHPRELISFLRKLPKVVLSKR----EV 248
Cdd:PRK10673  79 QIEKATFIGHSMGGKAVMALTALAPDRIDKLV---AIDIAPvdYHVR-------RHDEIFAAINAVSEAGATTRqqaaAI 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891  249 LKALINEgfsNDVAQWVItnlrptgpsaSSF---SWTFDLdgiAELYQSYEETNLWNFVENLPRGVHvnFLKAERSLHrw 325
Cdd:PRK10673 149 MRQHLNE---EGVIQFLL----------KSFvdgEWRFNV---PVLWDQYPHIVGWEKIPAWPHPAL--FIRGGNSPY-- 208

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 15234891  326 aLEDLQRihaaEELASEEGGGvEMHVLEDAGHWVHTDNPDGLFR 369
Cdd:PRK10673 209 -VTEAYR----DDLLAQFPQA-RAHVIAGAGHWVHAEKPDAVLR 246
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 107-364 1.14e-14

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 72.92  E-value: 1.14e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   107 PTAVLLHGILGSGKNWGTFARRLAHefPTWQFLLVDLRCHGDSTSLKKRGPHSVATTASDVLKLVGQLRLTPRVLVGHSF 186
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALAR--DGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   187 GGKVVLSMVEQAakplPRPVRAWVLDATPgkvragGDGEDHPRELISFLRKLPKVvlskrevlkaliNEGFSNDVAQWVI 266
Cdd:pfam00561  79 GGLIALAYAAKY----PDRVKALVLLGAL------DPPHELDEADRFILALFPGF------------FDGFVADFAPNPL 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   267 TNLRPTgPSASSFSWTFDLDGIAELYQSYEETNLWNFVeNLPRGVHVNFL----KAERSLHRWALEDLQRIHAAEELASE 342
Cdd:pfam00561 137 GRLVAK-LLALLLLRLRLLKALPLLNKRFPSGDYALAK-SLVTGALLFIEtwstELRAKFLGRLDEPTLIIWGDQDPLVP 214

                         250       260       270
                  ....*....|....*....|....*....|.
gi 15234891   343 EGG---------GVEMHVLEDAGHWVHTDNP 364
Cdd:pfam00561 215 PQAleklaqlfpNARLVVIPDAGHFAFLEGP 245
 
Name Accession Description Interval E-value
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 104-371 8.47e-21

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 89.68  E-value: 8.47e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 104 PDTPTAVLLHGILGSGKNWGTFARRLAHEFptwQFLLVDLRCHGDSTslKKRGPHSVATTASDVLKLVGQLRLTPRVLVG 183
Cdd:COG0596  21 PDGPPVVLLHGLPGSSYEWRPLIPALAAGY---RVIAPDLRGHGRSD--KPAGGYTLDDLADDLAALLDALGLERVVLVG 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 184 HSFGGKVVLSMVEQAakplPRPVRAWVLdatpgkvraggdgedhprelisflrklpkvvlskrevlkalinegfSNDVAQ 263
Cdd:COG0596  96 HSMGGMVALELAARH----PERVAGLVL----------------------------------------------VDEVLA 125

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 264 WVITNLRPTGpsassfswtFDLDGIAELYQSYEETNLWNFVENLPRGVHVnfLKAERSlhrwaleDLQRIHAAEELAsEE 343
Cdd:COG0596 126 ALAEPLRRPG---------LAPEALAALLRALARTDLRERLARITVPTLV--IWGEKD-------PIVPPALARRLA-EL 186

                       250       260
                ....*....|....*....|....*...
gi 15234891 344 GGGVEMHVLEDAGHWVHTDNPDGLFRIL 371
Cdd:COG0596 187 LPNAELVVLPGAGHFPPLEQPEAFAAAL 214
PRK10673 PRK10673
esterase;
96-369 6.99e-15

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 73.61  E-value: 6.99e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   96 RWKDDKSVPDTPTAVLLHGILGSGKNWGTFARRLAHEFPTWQfllVDLRCHGdstsLKKRGPH-SVATTASDVLKLVGQL 174
Cdd:PRK10673   6 RAQTAQNPHNNSPIVLVHGLFGSLDNLGVLARDLVNDHDIIQ---VDMRNHG----LSPRDPVmNYPAMAQDLLDTLDAL 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891  175 RLTPRVLVGHSFGGKVVLSMVEQAAKPLPRPVrawVLDATP--GKVRaggdgedHPRELISFLRKLPKVVLSKR----EV 248
Cdd:PRK10673  79 QIEKATFIGHSMGGKAVMALTALAPDRIDKLV---AIDIAPvdYHVR-------RHDEIFAAINAVSEAGATTRqqaaAI 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891  249 LKALINEgfsNDVAQWVItnlrptgpsaSSF---SWTFDLdgiAELYQSYEETNLWNFVENLPRGVHvnFLKAERSLHrw 325
Cdd:PRK10673 149 MRQHLNE---EGVIQFLL----------KSFvdgEWRFNV---PVLWDQYPHIVGWEKIPAWPHPAL--FIRGGNSPY-- 208

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 15234891  326 aLEDLQRihaaEELASEEGGGvEMHVLEDAGHWVHTDNPDGLFR 369
Cdd:PRK10673 209 -VTEAYR----DDLLAQFPQA-RAHVIAGAGHWVHAEKPDAVLR 246
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 107-364 1.14e-14

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 72.92  E-value: 1.14e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   107 PTAVLLHGILGSGKNWGTFARRLAHefPTWQFLLVDLRCHGDSTSLKKRGPHSVATTASDVLKLVGQLRLTPRVLVGHSF 186
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPALAR--DGFRVIALDLRGFGKSSRPKAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   187 GGKVVLSMVEQAakplPRPVRAWVLDATPgkvragGDGEDHPRELISFLRKLPKVvlskrevlkaliNEGFSNDVAQWVI 266
Cdd:pfam00561  79 GGLIALAYAAKY----PDRVKALVLLGAL------DPPHELDEADRFILALFPGF------------FDGFVADFAPNPL 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   267 TNLRPTgPSASSFSWTFDLDGIAELYQSYEETNLWNFVeNLPRGVHVNFL----KAERSLHRWALEDLQRIHAAEELASE 342
Cdd:pfam00561 137 GRLVAK-LLALLLLRLRLLKALPLLNKRFPSGDYALAK-SLVTGALLFIEtwstELRAKFLGRLDEPTLIIWGDQDPLVP 214

                         250       260       270
                  ....*....|....*....|....*....|.
gi 15234891   343 EGG---------GVEMHVLEDAGHWVHTDNP 364
Cdd:pfam00561 215 PQAleklaqlfpNARLVVIPDAGHFAFLEGP 245
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
95-214 2.19e-11

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 63.10  E-value: 2.19e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891  95 WRWKDDKSVPdtPTAVLLHGILGSGKNWGTFARRLAHEFptWQFLLVDLRCHGDSTSLKKRGPhSVATTASDVLKLVGQL 174
Cdd:COG2267  19 RRWRPAGSPR--GTVVLVHGLGEHSGRYAELAEALAAAG--YAVLAFDLRGHGRSDGPRGHVD-SFDDYVDDLRAALDAL 93

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 15234891 175 RL---TPRVLVGHSFGGKVVLSMVEQAakplPRPVRAWVLDAT 214
Cdd:COG2267  94 RArpgLPVVLLGHSMGGLIALLYAARY----PDRVAGLVLLAP 132
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 110-370 1.63e-09

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 57.48  E-value: 1.63e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   110 VLLHGilgSGKNWGTFARRLAHEFPTWqflLVDLRCHGDStslkkRGPHSVATTASDVLKLVGQLR-LTPRVLVGHSFGG 188
Cdd:pfam12697   2 VLVHG---AGLSAAPLAALLAAGVAVL---APDLPGHGSS-----SPPPLDLADLADLAALLDELGaARPVVLVGHSLGG 70

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   189 KVVLSMVEQAakplprPVRAWVLDATpgkvragGDGEDHPRELISFLRKLPKVVLSKREVLKALINEGFSNDVAQWVitn 268
Cdd:pfam12697  71 AVALAAAAAA------LVVGVLVAPL-------AAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPADA--- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   269 lrptgpsassfSWTFDLDGIAELYQSYeetnLWNFVENLPRGVHVNFLKAERSlhRWALEDLQRIHAAEElaseeggGVE 348
Cdd:pfam12697 135 -----------EWAAALARLAALLAAL----ALLPLAAWRDLPVPVLVLAEED--RLVPELAQRLLAALA-------GAR 190

                         250       260
                  ....*....|....*....|..
gi 15234891   349 MHVLEDAGHWVHtDNPDGLFRI 370
Cdd:pfam12697 191 LVVLPGAGHLPL-DDPEEVAEA 211
PRK11126 PRK11126
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional
 105-192 2.70e-08

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; Provisional


Pssm-ID: 236855 [Multi-domain]  Cd Length: 242  Bit Score: 54.07  E-value: 2.70e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891  105 DTPTAVLLHGILGSGKNWgtfaRRLAHEFPTWQFLLVDLRCHGDSTSLKkrgPHSVATTASDVLKLVGQLRLTPRVLVGH 184
Cdd:PRK11126   1 GLPWLVFLHGLLGSGQDW----QPVGEALPDYPRLYIDLPGHGGSAAIS---VDGFADVSRLLSQTLQSYNILPYWLVGY 73


                 ....*...
gi 15234891  185 SFGGKVVL 192
Cdd:PRK11126  74 SLGGRIAM 81
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 88-216 5.03e-07

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 51.10  E-value: 5.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   88 VQGALVKWRwkdDKSVPDTPTAVLLHGILGSGKNW-GTFARrLAHEFPTWQFllvDLRCHGDSTslKKRGPHSVATTASD 166
Cdd:PRK14875 116 IGGRTVRYL---RLGEGDGTPVVLIHGFGGDLNNWlFNHAA-LAAGRPVIAL---DLPGHGASS--KAVGAGSLDELAAA 186

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 15234891  167 VLKLVGQLRLTPRVLVGHSFGGKVVLSMVEQAakplPRPVRAWVLDATPG 216
Cdd:PRK14875 187 VLAFLDALGIERAHLVGHSMGGAVALRLAARA----PQRVASLTLIAPAG 232
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 107-272 2.00e-05

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 45.68  E-value: 2.00e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 107 PTAVLLHGILGSGKNWGTFARRLAHEfpTWQFLLVDLRCHGDSTslkkrG-PHSVAT----TASDVLKLVGQLRLTPR-- 179
Cdd:COG1073  38 PAVVVAHGNGGVKEQRALYAQRLAEL--GFNVLAFDYRGYGESE-----GePREEGSperrDARAAVDYLRTLPGVDPer 110

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 180 -VLVGHSFGGKVVLSmveqAAKPLPRpVRAWVLDATPGKVRAGGDGedhpRELISFLRKLPKVVLSKREVLKALINEGFs 258
Cdd:COG1073 111 iGLLGISLGGGYALN----AAATDPR-VKAVILDSPFTSLEDLAAQ----RAKEARGAYLPGVPYLPNVRLASLLNDEF- 180

                       170
                ....*....|....
gi 15234891 259 nDVAQWVITNLRPT 272
Cdd:COG1073 181 -DPLAKIEKISRPL 193
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 110-215 2.39e-04

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 40.20  E-value: 2.39e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891 110 VLLHGILGSGKNWGTFARRLAHE-FPTWQFLLvdlrchgDSTSlkkrgpHSVATTASDVLKLVGQLRLTPR----VLVGH 184
Cdd:COG1075   9 VLVHGLGGSAASWAPLAPRLRAAgYPVYALNY-------PSTN------GSIEDSAEQLAAFVDAVLAATGaekvDLVGH 75

                        90       100       110
                ....*....|....*....|....*....|.
gi 15234891 185 SFGGKVVLSMVEQAAKplPRPVRAWVLDATP 215
Cdd:COG1075  76 SMGGLVARYYLKRLGG--AAKVARVVTLGTP 104
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 110-246 1.56e-03

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 39.51  E-value: 1.56e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   110 VLLHGILGSGKNWGTFARRLAHefPTWQFLLVDLRCHGDSTSlkKRG-PHSVATTASDVLKLVGQLRL----TPRVLVGH 184
Cdd:pfam12146   8 VLVHGLGEHSGRYAHLADALAA--QGFAVYAYDHRGHGRSDG--KRGhVPSFDDYVDDLDTFVDKIREehpgLPLFLLGH 83

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15234891   185 SFGGKVVLSMVEQAakplPRPVRAWVLDATPGKVRAGGDgedhPRELISFLRKLPKVVLSKR 246
Cdd:pfam12146  84 SMGGLIAALYALRY----PDKVDGLILSAPALKIKPYLA----PPILKLLAKLLGKLFPRLR 137
PLN02980 PLN02980
2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate ...
 109-216 2.66e-03

2-oxoglutarate decarboxylase/ hydro-lyase/ magnesium ion binding / thiamin pyrophosphate binding


Pssm-ID: 215530 [Multi-domain]  Cd Length: 1655  Bit Score: 39.84  E-value: 2.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15234891   109 AVLLHGILGSGKNWGTFARRLAhefPTWQFLLVDLRCHGDSTSLK------KRGPHSVATTASDVLKLVGQLRLTPRVLV 182
Cdd:PLN02980 1374 VLFLHGFLGTGEDWIPIMKAIS---GSARCISIDLPGHGGSKIQNhaketqTEPTLSVELVADLLYKLIEHITPGKVTLV 1450

                          90       100       110
                  ....*....|....*....|....*....|....
gi 15234891   183 GHSFGGKVVLSMveqAAKPLPRPVRAWVLDATPG 216
Cdd:PLN02980 1451 GYSMGARIALYM---ALRFSDKIEGAVIISGSPG 1481
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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