NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|42568179|ref|NP_198638|]
View 

alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

Protein Classification

alpha/beta hydrolase( domain architecture ID 11437497)

alpha/beta hydrolase catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
47-242 1.78e-35

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


:

Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 129.26  E-value: 1.78e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  47 LKTRRGNEIVA-IYIKH--PKANGTLLYSHGNAADLGQMFeLFIELSNRLRLNLMGYDYSGYGQSTGKASECNTYA--DI 121
Cdd:COG1073  15 FKSRDGIKLAGdLYLPAgaSKKYPAVVVAHGNGGVKEQRA-LYAQRLAELGFNVLAFDYRGYGESEGEPREEGSPErrDA 93
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 122 DAAYTCLKEHYGVKDDQLILYGQSVGSGPTIDLASRTPNLRGVVLHSPILS-----------------GMRVLYPVKRTY 184
Cdd:COG1073  94 RAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPRVKAVILDSPFTSledlaaqrakeargaylPGVPYLPNVRLA 173
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 185 WF--DIYKNIDKIGAVTCPVLVIHGTADEVVDCSHGKQLWELSKEKYEPLWVSGGGHCNL 242
Cdd:COG1073 174 SLlnDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEAAAEPKELLIVPGAGHVDL 233
 
Name Accession Description Interval E-value
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
47-242 1.78e-35

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 129.26  E-value: 1.78e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  47 LKTRRGNEIVA-IYIKH--PKANGTLLYSHGNAADLGQMFeLFIELSNRLRLNLMGYDYSGYGQSTGKASECNTYA--DI 121
Cdd:COG1073  15 FKSRDGIKLAGdLYLPAgaSKKYPAVVVAHGNGGVKEQRA-LYAQRLAELGFNVLAFDYRGYGESEGEPREEGSPErrDA 93
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 122 DAAYTCLKEHYGVKDDQLILYGQSVGSGPTIDLASRTPNLRGVVLHSPILS-----------------GMRVLYPVKRTY 184
Cdd:COG1073  94 RAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPRVKAVILDSPFTSledlaaqrakeargaylPGVPYLPNVRLA 173
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 185 WF--DIYKNIDKIGAVTCPVLVIHGTADEVVDCSHGKQLWELSKEKYEPLWVSGGGHCNL 242
Cdd:COG1073 174 SLlnDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEAAAEPKELLIVPGAGHVDL 233
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
62-248 5.87e-07

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 49.91  E-value: 5.87e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179    62 HPKAngTLLYSHGnaadlgqmfelFIELSNRL-----RLNLMGY-----DYSGYGQSTGKASECNTY----ADIDAAYTC 127
Cdd:pfam12146   2 EPRA--VVVLVHG-----------LGEHSGRYahladALAAQGFavyayDHRGHGRSDGKRGHVPSFddyvDDLDTFVDK 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179   128 LKEHYGVKDdqLILYGQSVGSGPTIDLASRTP-NLRGVVLHSPILSG------------MRVLYPVKRTYWF-------D 187
Cdd:pfam12146  69 IREEHPGLP--LFLLGHSMGGLIAALYALRYPdKVDGLILSAPALKIkpylappilkllAKLLGKLFPRLRVpnnllpdS 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179   188 IYKNIDKI--------------------------------GAVTCPVLVIHGTADEVVDCSHGKQLwelskekYEPLwvs 235
Cdd:pfam12146 147 LSRDPEVVaayaadplvhggisartlyelldagerllrraAAITVPLLLLHGGADRVVDPAGSREF-------YERA--- 216
                         250
                  ....*....|...
gi 42568179   236 GGGHCNLELYPEF 248
Cdd:pfam12146 217 GSTDKTLKLYPGL 229
PHA02857 PHA02857
monoglyceride lipase; Provisional
59-216 1.13e-03

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 40.25  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179   59 YIKHPKAngTLLYSHGNAADLGQMFELFIELSnRLRLNLMGYDYSGYGQSTGK---ASECNTYA-DIDAAYTCLKEHY-G 133
Cdd:PHA02857  20 PITYPKA--LVFISHGAGEHSGRYEELAENIS-SLGILVFSHDHIGHGRSNGEkmmIDDFGVYVrDVVQHVVTIKSTYpG 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  134 VKddqLILYGQSVGSGPTIDLASRTPNL-RGVVLHSPILSG-------------MRVLYPVK-----------------R 182
Cdd:PHA02857  97 VP---VFLLGHSMGATISILAAYKNPNLfTAMILMSPLVNAeavprlnllaaklMGIFYPNKivgklcpesvsrdmdevY 173
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 42568179  183 TYWFDIYKNIDKIGAVTC-------------------PVLVIHGTADEVVDCS 216
Cdd:PHA02857 174 KYQYDPLVNHEKIKAGFAsqvlkatnkvrkiipkiktPILILQGTNNEISDVS 226
 
Name Accession Description Interval E-value
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
47-242 1.78e-35

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 129.26  E-value: 1.78e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  47 LKTRRGNEIVA-IYIKH--PKANGTLLYSHGNAADLGQMFeLFIELSNRLRLNLMGYDYSGYGQSTGKASECNTYA--DI 121
Cdd:COG1073  15 FKSRDGIKLAGdLYLPAgaSKKYPAVVVAHGNGGVKEQRA-LYAQRLAELGFNVLAFDYRGYGESEGEPREEGSPErrDA 93
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 122 DAAYTCLKEHYGVKDDQLILYGQSVGSGPTIDLASRTPNLRGVVLHSPILS-----------------GMRVLYPVKRTY 184
Cdd:COG1073  94 RAAVDYLRTLPGVDPERIGLLGISLGGGYALNAAATDPRVKAVILDSPFTSledlaaqrakeargaylPGVPYLPNVRLA 173
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 185 WF--DIYKNIDKIGAVTCPVLVIHGTADEVVDCSHGKQLWELSKEKYEPLWVSGGGHCNL 242
Cdd:COG1073 174 SLlnDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDLYEAAAEPKELLIVPGAGHVDL 233
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
47-256 1.82e-24

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 99.32  E-value: 1.82e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  47 LKTRRGNEIVAIYIKhPKANG---TLLYSHGNAADLGQMFELFIELsnrlrLNLMGY-----DYSGYGQSTGKASEcNTY 118
Cdd:COG1506   2 FKSADGTTLPGWLYL-PADGKkypVVVYVHGGPGSRDDSFLPLAQA-----LASRGYavlapDYRGYGESAGDWGG-DEV 74
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 119 ADIDAAYTCLKEHYGVKDDQLILYGQSVGSGPTIDLASRTPNL-RGVVLHSPI------------LSGMRVLYPVKRTYW 185
Cdd:COG1506  75 DDVLAAIDYLAARPYVDPDRIGIYGHSYGGYMALLAAARHPDRfKAAVALAGVsdlrsyygttreYTERLMGGPWEDPEA 154
                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 42568179 186 FDIYKNIDKIGAVTCPVLVIHGTADEVVDCSHGKQLWELSKEKYEP---LWVSGGGHC-----NLELYPEFIKHLKKYV 256
Cdd:COG1506 155 YAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPvelLVYPGEGHGfsgagAPDYLERILDFLDRHL 233
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
47-239 9.68e-23

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 94.30  E-value: 9.68e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  47 LKTRRGNEI-VAIYIKHPKANGTLLYSHGNAADLGQMFELFIELSNRlRLNLMGYDYSGYGQSTGKASECNTY----ADI 121
Cdd:COG2267   8 LPTRDGLRLrGRRWRPAGSPRGTVVLVHGLGEHSGRYAELAEALAAA-GYAVLAFDLRGHGRSDGPRGHVDSFddyvDDL 86
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 122 DAAYTCLKEHYGVKddqLILYGQSVGSGPTIDLASRTPN-LRGVVLHSPILSGMRVLYPVKRtyWFDIYKNIDKIGAVTC 200
Cdd:COG2267  87 RAALDALRARPGLP---VVLLGHSMGGLIALLYAARYPDrVAGLVLLAPAYRADPLLGPSAR--WLRALRLAEALARIDV 161
                       170       180       190
                ....*....|....*....|....*....|....*....
gi 42568179 201 PVLVIHGTADEVVDCSHGKQLWELSKEKYEPLWVSGGGH 239
Cdd:COG2267 162 PVLVLHGGADRVVPPEAARRLAARLSPDVELVLLPGARH 200
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
68-252 1.64e-13

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 68.87  E-value: 1.64e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  68 TLLYSHGNAADLGQMFELFIELSNRLRLnlMGYDYSGYGQSTGKASECNTYADIDAAYTCLkEHYGVkdDQLILYGQSVG 147
Cdd:COG0596  25 PVVLLHGLPGSSYEWRPLIPALAAGYRV--IAPDLRGHGRSDKPAGGYTLDDLADDLAALL-DALGL--ERVVLVGHSMG 99
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 148 SGPTIDLASRTPN-LRGVVLHSPILSGMRVLYPVKRTY---------WFDIYKNIDKIGAVTCPVLVIHGTADEVVDCSH 217
Cdd:COG0596 100 GMVALELAARHPErVAGLVLVDEVLAALAEPLRRPGLApealaallrALARTDLRERLARITVPTLVIWGEKDPIVPPAL 179
                       170       180       190
                ....*....|....*....|....*....|....*.
gi 42568179 218 GKQLWELSKeKYEPLWVSGGGHC-NLELYPEFIKHL 252
Cdd:COG0596 180 ARRLAELLP-NAELVVLPGAGHFpPLEQPEAFAAAL 214
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
70-239 4.09e-10

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 59.18  E-value: 4.09e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  70 LYSHGNAADLGQMfelfIELSNRLR---LNLMGYDYSGYGQSTGKASECNT---YADIDAAYTCLKEHYgvkdDQLILYG 143
Cdd:COG1647  19 LLLHGFTGSPAEM----RPLAEALAkagYTVYAPRLPGHGTSPEDLLKTTWedwLEDVEEAYEILKAGY----DKVIVIG 90
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 144 QSVGSGPTIDLASRTPNLRGVVLHSPILS-------GMRVLYPVKRT---------------YWFDIY------------ 189
Cdd:COG1647  91 LSMGGLLALLLAARYPDVAGLVLLSPALKiddpsapLLPLLKYLARSlrgigsdiedpevaeYAYDRTplralaelqrli 170
                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 42568179 190 ----KNIDKIgavTCPVLVIHGTADEVVDCSHGKQLWE-LSKEKYEPLWVSGGGH 239
Cdd:COG1647 171 revrRDLPKI---TAPTLIIQSRKDEVVPPESARYIYErLGSPDKELVWLEDSGH 222
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
94-213 5.78e-08

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 52.66  E-value: 5.78e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  94 RLNLMGY-----DYSGYGQSTGKASECNTY----------ADIDAAYTCLKEHYGVKDDQLILYGQSVGSGPTIDLASRT 158
Cdd:COG0412  51 RLAAAGYvvlapDLYGRGGPGDDPDEARALmgaldpellaADLRAALDWLKAQPEVDAGRVGVVGFCFGGGLALLAAARG 130
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 42568179 159 PNLRGVVlhspILSGMRVLYPvkrtywfdiykNIDKIGAVTCPVLVIHGTADEVV 213
Cdd:COG0412 131 PDLAAAV----SFYGGLPADD-----------LLDLAARIKAPVLLLYGEKDPLV 170
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
62-248 5.87e-07

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 49.91  E-value: 5.87e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179    62 HPKAngTLLYSHGnaadlgqmfelFIELSNRL-----RLNLMGY-----DYSGYGQSTGKASECNTY----ADIDAAYTC 127
Cdd:pfam12146   2 EPRA--VVVLVHG-----------LGEHSGRYahladALAAQGFavyayDHRGHGRSDGKRGHVPSFddyvDDLDTFVDK 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179   128 LKEHYGVKDdqLILYGQSVGSGPTIDLASRTP-NLRGVVLHSPILSG------------MRVLYPVKRTYWF-------D 187
Cdd:pfam12146  69 IREEHPGLP--LFLLGHSMGGLIAALYALRYPdKVDGLILSAPALKIkpylappilkllAKLLGKLFPRLRVpnnllpdS 146
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179   188 IYKNIDKI--------------------------------GAVTCPVLVIHGTADEVVDCSHGKQLwelskekYEPLwvs 235
Cdd:pfam12146 147 LSRDPEVVaayaadplvhggisartlyelldagerllrraAAITVPLLLLHGGADRVVDPAGSREF-------YERA--- 216
                         250
                  ....*....|...
gi 42568179   236 GGGHCNLELYPEF 248
Cdd:pfam12146 217 GSTDKTLKLYPGL 229
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
67-174 1.70e-06

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 48.65  E-value: 1.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179    67 GTLLYSHGNAADLGqMFELFIELSNRLRLNLMGYDYSGYGQSTgKASECNTYADIDAA--YTCLKEHYGvkDDQLILYGQ 144
Cdd:pfam00561   1 PPVLLLHGLPGSSD-LWRKLAPALARDGFRVIALDLRGFGKSS-RPKAQDDYRTDDLAedLEYILEALG--LEKVNLVGH 76
                          90       100       110
                  ....*....|....*....|....*....|.
gi 42568179   145 SVGSGPTIDLASRTPNL-RGVVLHSPILSGM 174
Cdd:pfam00561  77 SMGGLIALAYAAKYPDRvKALVLLGALDPPH 107
COG2945 COG2945
Alpha/beta superfamily hydrolase [General function prediction only];
93-239 9.56e-06

Alpha/beta superfamily hydrolase [General function prediction only];


Pssm-ID: 442188 [Multi-domain]  Cd Length: 201  Bit Score: 45.54  E-value: 9.56e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  93 LRLNlmgydYSGYGQSTGkasecnTY-------ADIDAAYTCLKEHYGvkdDQLILYGQSVGSGPTIDLASRTPNLRGVV 165
Cdd:COG2945  59 LRFN-----FRGVGRSEG------EFdegrgelDDAAAALDWLRAQNP---LPLWLAGFSFGAYVALQLAMRLPEVEGLI 124
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 42568179 166 LHSPilsgmrvlyPVKRtywFDIykniDKIGAVTCPVLVIHGTADEVVDCSHGKQLWELSKEKYEPLWVSGGGH 239
Cdd:COG2945 125 LVAP---------PVNR---YDF----SFLAPCPAPTLVIHGEQDEVVPPAEVLDWARPLSPPLPVVVVPGADH 182
YpfH COG0400
Predicted esterase [General function prediction only];
119-256 4.64e-05

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 43.74  E-value: 4.64e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 119 ADIDAAYTCLKEHYGVKDDQLILYGQSVGSGPTIDLASRTPN-LRGVVLhspiLSGMRVLYPVKRTYWFDiyknidkigA 197
Cdd:COG0400  71 EALAAFIDELEARYGIDPERIVLAGFSQGAAMALSLALRRPElLAGVVA----LSGYLPGEEALPAPEAA---------L 137
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 42568179 198 VTCPVLVIHGTADEVVDCSHGKQLWE-LSKEKYEPLWVS-GGGHcnlELYPEFIKHLKKYV 256
Cdd:COG0400 138 AGTPVFLAHGTQDPVIPVERAREAAEaLEAAGADVTYREyPGGH---EISPEELADARAWL 195
PHA02857 PHA02857
monoglyceride lipase; Provisional
59-216 1.13e-03

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 40.25  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179   59 YIKHPKAngTLLYSHGNAADLGQMFELFIELSnRLRLNLMGYDYSGYGQSTGK---ASECNTYA-DIDAAYTCLKEHY-G 133
Cdd:PHA02857  20 PITYPKA--LVFISHGAGEHSGRYEELAENIS-SLGILVFSHDHIGHGRSNGEkmmIDDFGVYVrDVVQHVVTIKSTYpG 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179  134 VKddqLILYGQSVGSGPTIDLASRTPNL-RGVVLHSPILSG-------------MRVLYPVK-----------------R 182
Cdd:PHA02857  97 VP---VFLLGHSMGATISILAAYKNPNLfTAMILMSPLVNAeavprlnllaaklMGIFYPNKivgklcpesvsrdmdevY 173
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 42568179  183 TYWFDIYKNIDKIGAVTC-------------------PVLVIHGTADEVVDCS 216
Cdd:PHA02857 174 KYQYDPLVNHEKIKAGFAsqvlkatnkvrkiipkiktPILILQGTNNEISDVS 226
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
120-214 1.22e-03

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 39.47  E-value: 1.22e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179 120 DIDAAYTCLKEH---YGVKDDQLILYGQSVGSGPTIDLASR-----TPNLRGVVLHSPILSgMRV---LYPVKRTywfdi 188
Cdd:COG0657  66 DAYAALRWLRANaaeLGIDPDRIAVAGDSAGGHLAAALALRardrgGPRPAAQVLIYPVLD-LTAsplRADLAGL----- 139
                        90       100
                ....*....|....*....|....*.
gi 42568179 189 yknidkigavtCPVLVIHGTADEVVD 214
Cdd:COG0657 140 -----------PPTLIVTGEADPLVD 154
DUF818 pfam05677
Chlamydia CHLPS protein (DUF818); This family consists of several Chlamydia CHLPS proteins, ...
21-147 8.89e-03

Chlamydia CHLPS protein (DUF818); This family consists of several Chlamydia CHLPS proteins, the function of which are unknown.


Pssm-ID: 253315  Cd Length: 364  Bit Score: 37.46  E-value: 8.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 42568179    21 SYGFVSDVDRLYItevpRRDDVDVlklktrrgnEIVAIYIKHPKANGTLLYSHGNAADL--GQMFEL----FIELSNRLR 94
Cdd:pfam05677 105 SKNRVSSVRRVPI----QQDDLLI---------DTLEICLPQAPPDRWMLISLGNSDCLeeRAMIGLkkssWQRLAKLIG 171
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 42568179    95 LNLMGYDYSGYGQSTGKASECNTYADIDAAYTCLKEH-YGVKDDQLILYGQSVG 147
Cdd:pfam05677 172 ANILVFNYPGVMSSTGSITRENLAKAYQACVRYLRDKeQGPGAKQIIAYGYSLG 225
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH