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heat shock-like protein [Arabidopsis thaliana]
Protein Classification
HSP90 family protein ( domain architecture ID 1903338 )
HSP90 (heat shock protein 90) family protein functions as a molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved in cell cycle control and signal transduction
List of domain hits
Name
Accession
Description
Interval
E-value
HSP90 super family
cl46693 Hsp90 protein;
5-700
0e+00
Hsp90 protein;
PTZ00272 :Pssm-ID: 481033
Cd Length: 701
Bit Score: 966.84
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 5 ETFAFQAEINQL L SLIINTFYSNKEIFLRELISN S SDA L DKIR FE SLTD K S K L DGQ P E L F IR L VPDK S NKTL SII D S GIG 84
Cdd:PTZ00272 3 ETFAFQAEINQL M SLIINTFYSNKEIFLRELISN A SDA C DKIR YQ SLTD P S V L GES P R L C IR V VPDK E NKTL TVE D N GIG 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 85 MTKADLVNNLGTIARSGTK E FMEAL Q AG A D V SMIGQFGVGFYSAYLVA EK V V VT T K H N D DE Q YVWES Q AGG S FT V T RDVD 164
Cdd:PTZ00272 83 MTKADLVNNLGTIARSGTK A FMEAL E AG G D M SMIGQFGVGFYSAYLVA DR V T VT S K N N S DE S YVWES S AGG T FT I T STPE 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 165 GE p LG RGT K ITL F LK D DQ L EYLE E RRLK D L V KKHSEFI S Y P I Y L WT EKTTEKE IS D DED ED EP K KENE GE V --- EEV D E E 241
Cdd:PTZ00272 163 SD - MK RGT R ITL H LK E DQ M EYLE P RRLK E L I KKHSEFI G Y D I E L MV EKTTEKE VT D EDE ED TK K ADED GE E pkv EEV K E G 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 242 K E KDG KK K KK I KEV SH E W E LI NK Q KP I W L R K P EEI TKEEYAAFYK SLT NDWED HL A V KHFSVEGQLEF KA I L FVPKRAPF 321
Cdd:PTZ00272 242 D E GKK KK T KK V KEV TK E Y E VQ NK H KP L W T R D P KDV TKEEYAAFYK AIS NDWED PA A T KHFSVEGQLEF RS I M FVPKRAPF 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 322 D L F DTR KK L NNIKLYVRRVFIMDNCE E L I P EY L S FVKGVVDS D DLPLNISRE T LQQNKILKVIRKN L VKKC I EMF N E I AE 401
Cdd:PTZ00272 322 D M F EPN KK R NNIKLYVRRVFIMDNCE D L C P DW L G FVKGVVDS E DLPLNISRE N LQQNKILKVIRKN I VKKC L EMF D E V AE 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 402 NKEDY TK FYE A F S KN L KLGIHED SQ NR G K IAD LLR YH ST K SG D EMT SF KDYVTRMK E GQK D I F YITG E SKK AV E N SPF L E 481
Cdd:PTZ00272 402 NKEDY KQ FYE Q F G KN I KLGIHED TA NR K K LME LLR FY ST E SG E EMT TL KDYVTRMK A GQK S I Y YITG D SKK KL E T SPF I E 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 482 RLKK RG Y EVL Y M VDA IDEY AVG Q L K EYDG KK LVSA TKEG L k LED E T EEEK KK REE K K KSF E N LCKT I KE I LGDKVEKV V V 561
Cdd:PTZ00272 482 QARR RG L EVL F M TEP IDEY VMQ Q V K DFED KK FACL TKEG V - HFE E S EEEK QQ REE E K AAC E K LCKT M KE V LGDKVEKV I V 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 562 S D R IVD SPC C LVT G E Y GW T A N ME R IM KA QALRDSSM SG YM S SKKTME I NP DNG I ME ELR K R AE AD K NDK S VKDLV M LL YE 641
Cdd:PTZ00272 561 S E R LST SPC I LVT S E F GW S A H ME Q IM RN QALRDSSM AQ YM M SKKTME L NP RHP I IK ELR R R VG AD E NDK A VKDLV F LL FD 640
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063728714 642 T A LLTSGF S L DE P NTF A A RI H RM L KLGLS I DE D E NVEEDGDMP E L -- E E DA A EE S K ME E VD 700
Cdd:PTZ00272 641 T S LLTSGF Q L ED P TGY A E RI N RM I KLGLS L DE E E EEAAEAPVA E T ap A E VT A GT S S ME Q VD 701
Name
Accession
Description
Interval
E-value
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
5-700
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 966.84
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 5 ETFAFQAEINQL L SLIINTFYSNKEIFLRELISN S SDA L DKIR FE SLTD K S K L DGQ P E L F IR L VPDK S NKTL SII D S GIG 84
Cdd:PTZ00272 3 ETFAFQAEINQL M SLIINTFYSNKEIFLRELISN A SDA C DKIR YQ SLTD P S V L GES P R L C IR V VPDK E NKTL TVE D N GIG 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 85 MTKADLVNNLGTIARSGTK E FMEAL Q AG A D V SMIGQFGVGFYSAYLVA EK V V VT T K H N D DE Q YVWES Q AGG S FT V T RDVD 164
Cdd:PTZ00272 83 MTKADLVNNLGTIARSGTK A FMEAL E AG G D M SMIGQFGVGFYSAYLVA DR V T VT S K N N S DE S YVWES S AGG T FT I T STPE 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 165 GE p LG RGT K ITL F LK D DQ L EYLE E RRLK D L V KKHSEFI S Y P I Y L WT EKTTEKE IS D DED ED EP K KENE GE V --- EEV D E E 241
Cdd:PTZ00272 163 SD - MK RGT R ITL H LK E DQ M EYLE P RRLK E L I KKHSEFI G Y D I E L MV EKTTEKE VT D EDE ED TK K ADED GE E pkv EEV K E G 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 242 K E KDG KK K KK I KEV SH E W E LI NK Q KP I W L R K P EEI TKEEYAAFYK SLT NDWED HL A V KHFSVEGQLEF KA I L FVPKRAPF 321
Cdd:PTZ00272 242 D E GKK KK T KK V KEV TK E Y E VQ NK H KP L W T R D P KDV TKEEYAAFYK AIS NDWED PA A T KHFSVEGQLEF RS I M FVPKRAPF 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 322 D L F DTR KK L NNIKLYVRRVFIMDNCE E L I P EY L S FVKGVVDS D DLPLNISRE T LQQNKILKVIRKN L VKKC I EMF N E I AE 401
Cdd:PTZ00272 322 D M F EPN KK R NNIKLYVRRVFIMDNCE D L C P DW L G FVKGVVDS E DLPLNISRE N LQQNKILKVIRKN I VKKC L EMF D E V AE 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 402 NKEDY TK FYE A F S KN L KLGIHED SQ NR G K IAD LLR YH ST K SG D EMT SF KDYVTRMK E GQK D I F YITG E SKK AV E N SPF L E 481
Cdd:PTZ00272 402 NKEDY KQ FYE Q F G KN I KLGIHED TA NR K K LME LLR FY ST E SG E EMT TL KDYVTRMK A GQK S I Y YITG D SKK KL E T SPF I E 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 482 RLKK RG Y EVL Y M VDA IDEY AVG Q L K EYDG KK LVSA TKEG L k LED E T EEEK KK REE K K KSF E N LCKT I KE I LGDKVEKV V V 561
Cdd:PTZ00272 482 QARR RG L EVL F M TEP IDEY VMQ Q V K DFED KK FACL TKEG V - HFE E S EEEK QQ REE E K AAC E K LCKT M KE V LGDKVEKV I V 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 562 S D R IVD SPC C LVT G E Y GW T A N ME R IM KA QALRDSSM SG YM S SKKTME I NP DNG I ME ELR K R AE AD K NDK S VKDLV M LL YE 641
Cdd:PTZ00272 561 S E R LST SPC I LVT S E F GW S A H ME Q IM RN QALRDSSM AQ YM M SKKTME L NP RHP I IK ELR R R VG AD E NDK A VKDLV F LL FD 640
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063728714 642 T A LLTSGF S L DE P NTF A A RI H RM L KLGLS I DE D E NVEEDGDMP E L -- E E DA A EE S K ME E VD 700
Cdd:PTZ00272 641 T S LLTSGF Q L ED P TGY A E RI N RM I KLGLS L DE E E EEAAEAPVA E T ap A E VT A GT S S ME Q VD 701
HSP90
pfam00183 Hsp90 protein;
184-697
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 841.83
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 184 EYLEE RRL K D LVKK H SEFI SY PIYLW T EK TT E K E IS D D E D E D E PKK E N E GEVEEVD EE KEKDGK KKK KI -- KE VSH EWEL 261
Cdd:pfam00183 1 EYLEE KKI K E LVKK Y SEFI NF PIYLW V EK EE E V E VP D E E E E E E EEE E E E EDDDPKV EE EDEEEE KKK TK kv KE TVW EWEL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 262 I NK Q KPIW L R K P E E I T K EEYA A FYKSL TN DWED H LAVKHFSVEG QL EFK AI LF V PKRAPFDLF DTR KK L NNIKLYVRRVF 341
Cdd:pfam00183 81 L NK T KPIW T R N P K E V T E EEYA E FYKSL SK DWED P LAVKHFSVEG EV EFK SL LF I PKRAPFDLF ENK KK K NNIKLYVRRVF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 342 I M D NC E E LIPEYL S FVKGVVDSDDLPLN I SRETLQQNKILKVI R K N LV K K CIE MF N EIAE N KEDY T KF YEA F S KNLKLGI 421
Cdd:pfam00183 161 I T D DF E D LIPEYL N FVKGVVDSDDLPLN V SRETLQQNKILKVI K K K LV R K ALD MF K EIAE E KEDY K KF WKE F G KNLKLGI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 422 H EDS Q NR G K I A D LLR YH S T KSGDE M TS FK DYV T RMKEGQK D I F YITGESK KA VENSPFLERLKK R GYEVLY MV D A IDEYA 501
Cdd:pfam00183 241 I EDS S NR N K L A K LLR FY S S KSGDE L TS LD DYV S RMKEGQK H I Y YITGESK EE VENSPFLERLKK K GYEVLY LT D P IDEYA 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 502 V G QLKE Y DGKKLV SAT KEGL k LED E T EEEKKK R EE K KK S FE N L C K TI K EI LGDKVEKVVVS D R I VDSPC C LVT GE YGW T A 581
Cdd:pfam00183 321 V Q QLKE F DGKKLV NVA KEGL - ELE E D EEEKKK D EE L KK E FE P L T K WL K DV LGDKVEKVVVS N R L VDSPC V LVT SQ YGW S A 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 582 NMERIMKAQALR - DSSMS G YMSSKKT M EINP DNG I ME EL R KR A EADK N DK SV KDL VM LLYETALL T SGFSL DE P NT FA A R 660
Cdd:pfam00183 400 NMERIMKAQALR k DSSMS S YMSSKKT L EINP RHP I IK EL L KR V EADK D DK TA KDL AL LLYETALL R SGFSL ED P AS FA S R 479
490 500 510
....*....|....*....|....*....|....*..
gi 1063728714 661 I H RMLKLGL S IDEDE N VEE DGDMP E L EE DAA EE SKM E 697
Cdd:pfam00183 480 I Y RMLKLGL G IDEDE I VEE EDEIE E E EE EEE EE PEE E 516
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
4-670
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 760.81
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 4 A ET FA FQAE IN QLL S L I I NTF YSNKEIFLRELISN S SDA L DK I RF ES LTD KSKLDGQPE L F IR LVP DK SN KTL S I I D S GI 83
Cdd:COG0326 3 K ET GE FQAE VK QLL D L M I HSL YSNKEIFLRELISN A SDA I DK L RF LA LTD PELKEEDGD L K IR IEV DK EA KTL T I S D N GI 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 84 GMT KADLVN NLGTIA R SGT K EF M E A L Q -- AGA D VSM IGQFGVGFYSA YL VA E KV V V T T KH -- N D D E QYV WES QAG G SF T V 159
Cdd:COG0326 83 GMT REEVIE NLGTIA K SGT R EF L E K L K gd QKK D SDL IGQFGVGFYSA FM VA D KV E V V T RS ag E D A E AVR WES DGD G EY T I 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 160 T rdv DG E PLG RGT K ITL F LK D D QL E Y LEE R RL KDLV KK H S E FI SY PI YLWT E KTTEK eisddededepkkenegeveevd 239
Cdd:COG0326 163 E --- EA E KAE RGT E ITL H LK E D AE E F LEE W RL REII KK Y S D FI PV PI KMEG E EEETE ----------------------- 216
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 240 eekekdgkkkkkikevsh E W E L IN KQKPI W L R KPE EIT K EEY AA FYK S L TN D W ED H L AVK H FS VEG QL E FKAI L FV PK R A 319
Cdd:COG0326 217 ------------------ E D E T IN SATAL W T R SKS EIT D EEY KE FYK H L FH D F ED P L FWI H LN VEG PF E YTGL L YI PK K A 278
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 320 PFDL F D TRK K l NN IKLYV R RVFIMD NC E E L I PEYL S FV K GVVDS D DLPLN I SRE T LQ QNKI LK V IRK NLV KK CIEMFNEI 399
Cdd:COG0326 279 PFDL Y D RDR K - GG IKLYV K RVFIMD DA E D L L PEYL R FV R GVVDS P DLPLN V SRE I LQ EDRQ LK K IRK AIT KK VLDELEKL 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 400 A E N - K E D Y T KF YEA F SKN LK L G IH ED SQ NR G KIADLLR YH STK s GDEMTSFKD YV T RMKEGQK D I F YITGES KK A V E N SP 478
Cdd:COG0326 358 A K N d R E K Y E KF WKE F GLV LK E G AL ED FK NR E KIADLLR FE STK - EGGYVTLAE YV E RMKEGQK K I Y YITGES RE A A E Q SP 436
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 479 F LE RL K KR G Y EVL YMV D A IDE YAVGQ L K E Y DGKK LV S ATKEG L kl EDETE EEKK KR EE KKKS F EN L CKTI KE I LGDKV EK 558
Cdd:COG0326 437 H LE IF K AK G I EVL LLT D P IDE FLISH L E E F DGKK FK S VDSGD L -- DLDKL EEKK ES EE EEEE F KP L LERF KE A LGDKV KD 514
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 559 V V VS D R IV DSP C CLV TG E YGWTAN ME RIM KA qalrdss M SGY M - SS K KTM EINP DNGIMEE L RKRAEADK ndks V KDL VM 637
Cdd:COG0326 515 V R VS A R LT DSP A CLV AD E GDMSRR ME KML KA ------- M GQD M p EA K PIL EINP NHPLVKK L AAEEDEEL ---- F KDL AE 583
650 660 670
....*....|....*....|....*....|...
gi 1063728714 638 LLY ET ALL TS G FS L DE P NT F AA R IHRM L KLG L S 670
Cdd:COG0326 584 LLY DQ ALL AE G GL L ED P AA F VK R LNKL L EKA L G 616
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
14-202
2.65e-109
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 328.71
E-value: 2.65e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 14 NQLL S LII NTF YSNKEIFLRELISN S SDALDK I R FE SLTD K S K LD GQ PEL F IR LV PDK S N K TL S I I D S GIGMTK AD L V NN 93
Cdd:cd16927 1 NQLL D LII HSL YSNKEIFLRELISN A SDALDK L R YL SLTD P S L LD DD PEL E IR IS PDK E N R TL T I S D T GIGMTK EE L I NN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 94 LGTIARSGTK E F M EALQ A GA - D VSM IGQFGVGFYSA YL VA E KV V VTTK HN - DDE Q Y V WES QA GGS F T VTRDVDG ep LGRG 171
Cdd:cd16927 81 LGTIARSGTK A F L EALQ E GA k D SDL IGQFGVGFYSA FM VA D KV T VTTK SA g DDE G Y R WES DG GGS Y T IEEAEGE -- LGRG 158
170 180 190
....*....|....*....|....*....|.
gi 1063728714 172 TKITL F LK D D QL E Y LEE R R L K D LVKK H S E FI 202
Cdd:cd16927 159 TKITL H LK E D AK E F LEE A R I K E LVKK Y S D FI 189
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
27-179
9.91e-11
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 59.20
E-value: 9.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 27 NKEIF LR ELI SN SS D ALD K IRF E sltdkskldg QPELFIR L VP D KSNKTLSII D S G I G MTKA DL vnnlgtiarsg T K E F M 106
Cdd:smart00387 1 GDPDR LR QVL SN LL D NAI K YTP E ---------- GGRITVT L ER D GDHVEITVE D N G P G IPPE DL ----------- E K I F E 59
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1063728714 107 EALQAGADVSM IG QF G V G FYSAYLVA E KV vvttkhnddeqyvwesqa GG SFT V TRD vdgep L G R GT KI T LF L K 179
Cdd:smart00387 60 PFFRTDKRSRK IG GT G L G LSIVKKLV E LH ------------------ GG EIS V ESE ----- P G G GT TF T IT L P 109
Name
Accession
Description
Interval
E-value
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
5-700
0e+00
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 966.84
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 5 ETFAFQAEINQL L SLIINTFYSNKEIFLRELISN S SDA L DKIR FE SLTD K S K L DGQ P E L F IR L VPDK S NKTL SII D S GIG 84
Cdd:PTZ00272 3 ETFAFQAEINQL M SLIINTFYSNKEIFLRELISN A SDA C DKIR YQ SLTD P S V L GES P R L C IR V VPDK E NKTL TVE D N GIG 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 85 MTKADLVNNLGTIARSGTK E FMEAL Q AG A D V SMIGQFGVGFYSAYLVA EK V V VT T K H N D DE Q YVWES Q AGG S FT V T RDVD 164
Cdd:PTZ00272 83 MTKADLVNNLGTIARSGTK A FMEAL E AG G D M SMIGQFGVGFYSAYLVA DR V T VT S K N N S DE S YVWES S AGG T FT I T STPE 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 165 GE p LG RGT K ITL F LK D DQ L EYLE E RRLK D L V KKHSEFI S Y P I Y L WT EKTTEKE IS D DED ED EP K KENE GE V --- EEV D E E 241
Cdd:PTZ00272 163 SD - MK RGT R ITL H LK E DQ M EYLE P RRLK E L I KKHSEFI G Y D I E L MV EKTTEKE VT D EDE ED TK K ADED GE E pkv EEV K E G 241
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 242 K E KDG KK K KK I KEV SH E W E LI NK Q KP I W L R K P EEI TKEEYAAFYK SLT NDWED HL A V KHFSVEGQLEF KA I L FVPKRAPF 321
Cdd:PTZ00272 242 D E GKK KK T KK V KEV TK E Y E VQ NK H KP L W T R D P KDV TKEEYAAFYK AIS NDWED PA A T KHFSVEGQLEF RS I M FVPKRAPF 321
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 322 D L F DTR KK L NNIKLYVRRVFIMDNCE E L I P EY L S FVKGVVDS D DLPLNISRE T LQQNKILKVIRKN L VKKC I EMF N E I AE 401
Cdd:PTZ00272 322 D M F EPN KK R NNIKLYVRRVFIMDNCE D L C P DW L G FVKGVVDS E DLPLNISRE N LQQNKILKVIRKN I VKKC L EMF D E V AE 401
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 402 NKEDY TK FYE A F S KN L KLGIHED SQ NR G K IAD LLR YH ST K SG D EMT SF KDYVTRMK E GQK D I F YITG E SKK AV E N SPF L E 481
Cdd:PTZ00272 402 NKEDY KQ FYE Q F G KN I KLGIHED TA NR K K LME LLR FY ST E SG E EMT TL KDYVTRMK A GQK S I Y YITG D SKK KL E T SPF I E 481
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 482 RLKK RG Y EVL Y M VDA IDEY AVG Q L K EYDG KK LVSA TKEG L k LED E T EEEK KK REE K K KSF E N LCKT I KE I LGDKVEKV V V 561
Cdd:PTZ00272 482 QARR RG L EVL F M TEP IDEY VMQ Q V K DFED KK FACL TKEG V - HFE E S EEEK QQ REE E K AAC E K LCKT M KE V LGDKVEKV I V 560
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 562 S D R IVD SPC C LVT G E Y GW T A N ME R IM KA QALRDSSM SG YM S SKKTME I NP DNG I ME ELR K R AE AD K NDK S VKDLV M LL YE 641
Cdd:PTZ00272 561 S E R LST SPC I LVT S E F GW S A H ME Q IM RN QALRDSSM AQ YM M SKKTME L NP RHP I IK ELR R R VG AD E NDK A VKDLV F LL FD 640
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1063728714 642 T A LLTSGF S L DE P NTF A A RI H RM L KLGLS I DE D E NVEEDGDMP E L -- E E DA A EE S K ME E VD 700
Cdd:PTZ00272 641 T S LLTSGF Q L ED P TGY A E RI N RM I KLGLS L DE E E EEAAEAPVA E T ap A E VT A GT S S ME Q VD 701
HSP90
pfam00183 Hsp90 protein;
184-697
0e+00
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 841.83
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 184 EYLEE RRL K D LVKK H SEFI SY PIYLW T EK TT E K E IS D D E D E D E PKK E N E GEVEEVD EE KEKDGK KKK KI -- KE VSH EWEL 261
Cdd:pfam00183 1 EYLEE KKI K E LVKK Y SEFI NF PIYLW V EK EE E V E VP D E E E E E E EEE E E E EDDDPKV EE EDEEEE KKK TK kv KE TVW EWEL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 262 I NK Q KPIW L R K P E E I T K EEYA A FYKSL TN DWED H LAVKHFSVEG QL EFK AI LF V PKRAPFDLF DTR KK L NNIKLYVRRVF 341
Cdd:pfam00183 81 L NK T KPIW T R N P K E V T E EEYA E FYKSL SK DWED P LAVKHFSVEG EV EFK SL LF I PKRAPFDLF ENK KK K NNIKLYVRRVF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 342 I M D NC E E LIPEYL S FVKGVVDSDDLPLN I SRETLQQNKILKVI R K N LV K K CIE MF N EIAE N KEDY T KF YEA F S KNLKLGI 421
Cdd:pfam00183 161 I T D DF E D LIPEYL N FVKGVVDSDDLPLN V SRETLQQNKILKVI K K K LV R K ALD MF K EIAE E KEDY K KF WKE F G KNLKLGI 240
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 422 H EDS Q NR G K I A D LLR YH S T KSGDE M TS FK DYV T RMKEGQK D I F YITGESK KA VENSPFLERLKK R GYEVLY MV D A IDEYA 501
Cdd:pfam00183 241 I EDS S NR N K L A K LLR FY S S KSGDE L TS LD DYV S RMKEGQK H I Y YITGESK EE VENSPFLERLKK K GYEVLY LT D P IDEYA 320
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 502 V G QLKE Y DGKKLV SAT KEGL k LED E T EEEKKK R EE K KK S FE N L C K TI K EI LGDKVEKVVVS D R I VDSPC C LVT GE YGW T A 581
Cdd:pfam00183 321 V Q QLKE F DGKKLV NVA KEGL - ELE E D EEEKKK D EE L KK E FE P L T K WL K DV LGDKVEKVVVS N R L VDSPC V LVT SQ YGW S A 399
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 582 NMERIMKAQALR - DSSMS G YMSSKKT M EINP DNG I ME EL R KR A EADK N DK SV KDL VM LLYETALL T SGFSL DE P NT FA A R 660
Cdd:pfam00183 400 NMERIMKAQALR k DSSMS S YMSSKKT L EINP RHP I IK EL L KR V EADK D DK TA KDL AL LLYETALL R SGFSL ED P AS FA S R 479
490 500 510
....*....|....*....|....*....|....*..
gi 1063728714 661 I H RMLKLGL S IDEDE N VEE DGDMP E L EE DAA EE SKM E 697
Cdd:pfam00183 480 I Y RMLKLGL G IDEDE I VEE EDEIE E E EE EEE EE PEE E 516
PRK05218
PRK05218 heat shock protein 90; Provisional
2-670
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 780.06
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 2 ADA ET FA FQAE IN QLL S L I I NTF YSNKEIFLRELISN S SDA L DK I RFE S LTD KSKLD G QPE L F IR LVP DK SNK TL S I I D S 81
Cdd:PRK05218 1 MAM ET GE FQAE VK QLL H L M I HSL YSNKEIFLRELISN A SDA I DK L RFE A LTD PALYE G DGD L K IR ISF DK EAR TL T I S D N 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 82 GIGMT KADLVN NLGTIA R SGTKEF M E A L Q -- AGA D VSM IGQFGVGFYSA YL VA E KV V V T T KH -- NDD E QYV WES QAG G SF 157
Cdd:PRK05218 81 GIGMT REEVIE NLGTIA K SGTKEF L E K L K gd QKK D SQL IGQFGVGFYSA FM VA D KV T V I T RS ag PAA E AVR WES DGE G EY 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 158 T VT r DVDG E P lg RGT K ITL F LK D D QL E Y L E E R R LKDLV KK H S E FI SY PI Y L WT E kttekeisddededepkkenegevee 237
Cdd:PRK05218 161 T IE - EIEK E E -- RGT E ITL H LK E D ED E F L D E W R IRSII KK Y S D FI PV PI K L EK E -------------------------- 211
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 238 vdeekekdgkkkkkikevsh E W E L IN KQKPI W L R KPE EIT K EEY AA FYK S L TN D WE D H L AVK H FS VEG QL E FKAI L FV PK 317
Cdd:PRK05218 212 -------------------- E E E T IN SASAL W T R SKS EIT D EEY KE FYK H L AH D FD D P L FWI H NN VEG PF E YTGL L YI PK 271
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 318 R APFDLF DTRK K l NNI KLYV R RVFIMD NC EEL I PEYL S FVKGV V DS D DLPLN I SRE T LQ QNKIL K V IRK NLV KK CIEMFN 397
Cdd:PRK05218 272 K APFDLF NRDR K - GGL KLYV K RVFIMD DA EEL L PEYL R FVKGV I DS E DLPLN V SRE I LQ EDRVV K K IRK AIT KK VLDELE 350
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 398 EI A E N - K E D Y T KF YEA F SKN LK L G IH ED SQ NR G K I A D LLR YH ST KS G d EMT S FKD YV T RMKEGQK D I F YITG E S KK A VE N 476
Cdd:PRK05218 351 KL A K N d R E K Y E KF WKE F GPV LK E G LY ED FA NR E K L A K LLR FA ST HE G - KYV S LAE YV E RMKEGQK K I Y YITG D S RE A AK N 429
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 477 SP F LE RL KK R G Y EVL YMV D A IDE YAVGQ L K E Y DGK KLV S ATKEG L K L ED E T EEEK KKR EE KKKS F EN L CKTI KE I LGDKV 556
Cdd:PRK05218 430 SP H LE LF KK K G I EVL LLT D P IDE FWISY L E E F DGK PFK S VARGD L D L GK E D EEEK EEK EE AEEE F KP L LERL KE A LGDKV 509
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 557 EK V VV S D R IV DSP C CLV TG E YGWTAN ME RIM KA Q alrdss MSGYMS SK KTM EINP DNGIMEE L RK raea DKNDKSV KDL V 636
Cdd:PRK05218 510 KD V RL S H R LT DSP A CLV AD E GDMSTQ ME KLL KA A ------ GQEVPE SK PIL EINP NHPLVKK L AD ---- EADEAKF KDL A 579
650 660 670
....*....|....*....|....*....|....
gi 1063728714 637 M LLY ET ALL TS G F SL DE P NT F AA R IHRM L KLG L S 670
Cdd:PRK05218 580 E LLY DQ ALL AE G G SL ED P AA F VK R LNEL L LKL L A 613
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
4-670
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 760.81
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 4 A ET FA FQAE IN QLL S L I I NTF YSNKEIFLRELISN S SDA L DK I RF ES LTD KSKLDGQPE L F IR LVP DK SN KTL S I I D S GI 83
Cdd:COG0326 3 K ET GE FQAE VK QLL D L M I HSL YSNKEIFLRELISN A SDA I DK L RF LA LTD PELKEEDGD L K IR IEV DK EA KTL T I S D N GI 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 84 GMT KADLVN NLGTIA R SGT K EF M E A L Q -- AGA D VSM IGQFGVGFYSA YL VA E KV V V T T KH -- N D D E QYV WES QAG G SF T V 159
Cdd:COG0326 83 GMT REEVIE NLGTIA K SGT R EF L E K L K gd QKK D SDL IGQFGVGFYSA FM VA D KV E V V T RS ag E D A E AVR WES DGD G EY T I 162
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 160 T rdv DG E PLG RGT K ITL F LK D D QL E Y LEE R RL KDLV KK H S E FI SY PI YLWT E KTTEK eisddededepkkenegeveevd 239
Cdd:COG0326 163 E --- EA E KAE RGT E ITL H LK E D AE E F LEE W RL REII KK Y S D FI PV PI KMEG E EEETE ----------------------- 216
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 240 eekekdgkkkkkikevsh E W E L IN KQKPI W L R KPE EIT K EEY AA FYK S L TN D W ED H L AVK H FS VEG QL E FKAI L FV PK R A 319
Cdd:COG0326 217 ------------------ E D E T IN SATAL W T R SKS EIT D EEY KE FYK H L FH D F ED P L FWI H LN VEG PF E YTGL L YI PK K A 278
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 320 PFDL F D TRK K l NN IKLYV R RVFIMD NC E E L I PEYL S FV K GVVDS D DLPLN I SRE T LQ QNKI LK V IRK NLV KK CIEMFNEI 399
Cdd:COG0326 279 PFDL Y D RDR K - GG IKLYV K RVFIMD DA E D L L PEYL R FV R GVVDS P DLPLN V SRE I LQ EDRQ LK K IRK AIT KK VLDELEKL 357
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 400 A E N - K E D Y T KF YEA F SKN LK L G IH ED SQ NR G KIADLLR YH STK s GDEMTSFKD YV T RMKEGQK D I F YITGES KK A V E N SP 478
Cdd:COG0326 358 A K N d R E K Y E KF WKE F GLV LK E G AL ED FK NR E KIADLLR FE STK - EGGYVTLAE YV E RMKEGQK K I Y YITGES RE A A E Q SP 436
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 479 F LE RL K KR G Y EVL YMV D A IDE YAVGQ L K E Y DGKK LV S ATKEG L kl EDETE EEKK KR EE KKKS F EN L CKTI KE I LGDKV EK 558
Cdd:COG0326 437 H LE IF K AK G I EVL LLT D P IDE FLISH L E E F DGKK FK S VDSGD L -- DLDKL EEKK ES EE EEEE F KP L LERF KE A LGDKV KD 514
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 559 V V VS D R IV DSP C CLV TG E YGWTAN ME RIM KA qalrdss M SGY M - SS K KTM EINP DNGIMEE L RKRAEADK ndks V KDL VM 637
Cdd:COG0326 515 V R VS A R LT DSP A CLV AD E GDMSRR ME KML KA ------- M GQD M p EA K PIL EINP NHPLVKK L AAEEDEEL ---- F KDL AE 583
650 660 670
....*....|....*....|....*....|...
gi 1063728714 638 LLY ET ALL TS G FS L DE P NT F AA R IHRM L KLG L S 670
Cdd:COG0326 584 LLY DQ ALL AE G GL L ED P AA F VK R LNKL L EKA L G 616
PTZ00130
PTZ00130 heat shock protein 90; Provisional
5-698
7.16e-169
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain]
Cd Length: 814
Bit Score: 504.58
E-value: 7.16e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 5 E TFAF Q A E INQ L LSL I I N TF Y SN KE I FLRELISN SS DAL D KIRF E SL T D K S K L DGQPE L F IR LVPD K SNKT LSI I D S GIG 84
Cdd:PTZ00130 66 E QHQY Q T E VTR L MDI I V N SL Y TQ KE V FLRELISN AA DAL E KIRF L SL S D E S V L GEEKK L E IR ISAN K EKNI LSI T D T GIG 145
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 85 MTK A DL V NNLGTIA R SGT KE F M EA L - QA G A D V S M IGQFGVGFYSA Y LVA E KV V V T TK H N D DEQY V WES Q A GGS FT VTR D V 163
Cdd:PTZ00130 146 MTK E DL I NNLGTIA K SGT SN F L EA I s KS G G D M S L IGQFGVGFYSA F LVA D KV I V Y TK N N N DEQY I WES T A DAK FT IYK D P 225
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 164 D G EP L G RGT K I T L F LK D D QLEYLEERR L K DL VK K H S E FI S YPIYL WT E KTTEK E ISD D EDEDEPKKE N EGE V EEVDEEKE 243
Cdd:PTZ00130 226 R G ST L K RGT R I S L H LK E D ATNLMNDKK L V DL IS K Y S Q FI Q YPIYL LH E NVYTE E VLA D IAKEMENDP N YDS V KVEETDDP 305
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 244 KDGKKKKKI K E vs HE W E L I N K QKPIWLR K P E E I T K E E Y AA F YKS L TNDWEDH L AVK HF SV EG QL EFK AILFV P K RAP FDL 323
Cdd:PTZ00130 306 NKKTRTVEK K V -- KK W K L M N E QKPIWLR P P K E L T D E D Y KK F FSV L SGFNDEP L YHI HF FA EG EI EFK CLIYI P S RAP SIN 383
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 324 FDTRK K L N N IKLYVRRV FIM D NCE E LI P E Y L SFVKGVVDSDDLPLN I SRE T LQQNKILK VIR K NL V K K CIEM F NEI ---- 399
Cdd:PTZ00130 384 DHLFT K Q N S IKLYVRRV LVA D EFV E FL P R Y M SFVKGVVDSDDLPLN V SRE Q LQQNKILK AVS K RI V R K ILDT F RTL ykeg 463
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 400 AE NKE D -------------------------- Y TKF Y EAFS K N LK L G IH ED SQ NR G KI AD LL RY h S T KSGDEMT S FKD Y V 453
Cdd:PTZ00130 464 KK NKE T lraelaketdeekkkeiqkkinepst Y KLI Y KEYR K Y LK T G CY ED DI NR N KI VK LL LF - K T MLHPKSI S LDT Y I 542
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 454 TR MK EG QK D I F Y IT G E S KKAVENS P F L ERL KK RGYE V LYMVDAI DE YA V GQLK EYDGKK LV S AT K e G LKLEDE TE E EKKK 533
Cdd:PTZ00130 543 EN MK PD QK F I Y Y AS G D S YEYLSKI P Q L QIF KK KNID V VFLTESV DE SC V QRVQ EYDGKK FK S IQ K - G EITFEL TE D EKKK 621
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 534 R E EK KK SFEN L CKT I KEI L GDKVE KV VV S D R I VD S PC CL V TG E Y G WTAN ME RI MK AQ a LRD S SMSGY MS SK K TM EINPD N 613
Cdd:PTZ00130 622 E E KV KK MYKA L IDV I SDT L RNQIF KV EI S R R L VD A PC AV V ST E W G LSGQ ME KL MK IN - VNN S DQIKA MS GQ K IL EINPD H 700
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 614 G IM EE L R KR AEADKN D KSVKDLVMLL Y ET A L L T SGF S L DEPNTF A ARIHRMLKLG L SI D EDENVEE - D GDMP E L ---- E E 688
Cdd:PTZ00130 701 P IM ID L L KR SVSNPK D SQLTESIKII Y QS A K L A SGF D L EDTADL A QIVYDHINQK L GV D NNLKIDD l D PAIF E T kkie Q E 780
730
....*....|
gi 1063728714 689 D AAEES K ME E 698
Cdd:PTZ00130 781 D SPDGQ K FH E 790
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
14-202
2.65e-109
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 328.71
E-value: 2.65e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 14 NQLL S LII NTF YSNKEIFLRELISN S SDALDK I R FE SLTD K S K LD GQ PEL F IR LV PDK S N K TL S I I D S GIGMTK AD L V NN 93
Cdd:cd16927 1 NQLL D LII HSL YSNKEIFLRELISN A SDALDK L R YL SLTD P S L LD DD PEL E IR IS PDK E N R TL T I S D T GIGMTK EE L I NN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 94 LGTIARSGTK E F M EALQ A GA - D VSM IGQFGVGFYSA YL VA E KV V VTTK HN - DDE Q Y V WES QA GGS F T VTRDVDG ep LGRG 171
Cdd:cd16927 81 LGTIARSGTK A F L EALQ E GA k D SDL IGQFGVGFYSA FM VA D KV T VTTK SA g DDE G Y R WES DG GGS Y T IEEAEGE -- LGRG 158
170 180 190
....*....|....*....|....*....|.
gi 1063728714 172 TKITL F LK D D QL E Y LEE R R L K D LVKK H S E FI 202
Cdd:cd16927 159 TKITL H LK E D AK E F LEE A R I K E LVKK Y S D FI 189
PRK14083
PRK14083 HSP90 family protein; Provisional
8-388
5.19e-32
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain]
Cd Length: 601
Bit Score: 131.60
E-value: 5.19e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 8 A FQ AEINQLLS L IINTF YS NKEIFL REL IS N SS DA L dkirfesl T DKSK LD GQPELF IR L - VP D KSNK TL SII D S GIG M T 86
Cdd:PRK14083 4 R FQ VDLRGVID L LSRHL YS SPRVYV REL LQ N AV DA I -------- T ARRA LD PTAPGR IR I e LT D AGGG TL IVE D N GIG L T 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 87 KADLVNN L G TI A RS GTKE fm E A L QAGAD v SMI GQFG V G FY S AY LVA EKV VV TTKHND D EQY V - W ESQ A G G SFT V t R DVDG 165
Cdd:PRK14083 76 EEEVHEF L A TI G RS SKRD -- E N L GFARN - DFL GQFG I G LL S CF LVA DEI VV VSRSAK D GPA V e W RGK A D G TYS V - R KLET 151
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 166 E PLGR GT KIT L FLKD D QL E Y LE ERRLKD L V KK HSEFISY PI YLWT EK ttekeisddededepkkenegeveevdeekekd 245
Cdd:PRK14083 152 E RAEP GT TVY L RPRP D AE E W LE RETVEE L A KK YGSLLPV PI RVEG EK --------------------------------- 198
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 246 gkkkkkikevshew ELI N KQK P I W L R KPE -- E ITK E EYA A FYKS - L TNDWE D H -- L A V KHFSV EG qlefka ILF V - P KRA 319
Cdd:PRK14083 199 -------------- GGV N ETP P P W T R DYP dp E TRR E ALL A YGEE l L GFTPL D V ip L D V PSGGL EG ------ VAY V l P YAV 258
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063728714 320 P fdl FDT R K K L nni KL Y VR R VFIMDNC E E L I P EYLS FV KG VV DS D D L PLNI SRE T L QQNKI L KVI R KN L 388
Cdd:PRK14083 259 S --- PAA R R K H --- RV Y LK R MLLSEEA E N L L P DWAF FV RC VV NT D E L RPTA SRE A L YEDDA L AAV R EE L 321
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
27-179
9.91e-11
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 59.20
E-value: 9.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 27 NKEIF LR ELI SN SS D ALD K IRF E sltdkskldg QPELFIR L VP D KSNKTLSII D S G I G MTKA DL vnnlgtiarsg T K E F M 106
Cdd:smart00387 1 GDPDR LR QVL SN LL D NAI K YTP E ---------- GGRITVT L ER D GDHVEITVE D N G P G IPPE DL ----------- E K I F E 59
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1063728714 107 EALQAGADVSM IG QF G V G FYSAYLVA E KV vvttkhnddeqyvwesqa GG SFT V TRD vdgep L G R GT KI T LF L K 179
Cdd:smart00387 60 PFFRTDKRSRK IG GT G L G LSIVKKLV E LH ------------------ GG EIS V ESE ----- P G G GT TF T IT L P 109
HATPase_c
pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
27-182
3.93e-06
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain]
Cd Length: 109
Bit Score: 46.21
E-value: 3.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 27 NK E IF LR ELI SN SS D ALD K IRFES ltdkskldgq P E LFIR L VPD k SNK TL SII D S GIG MTKA DL vnnlgti A R SGTK e F M 106
Cdd:pfam02518 1 GD E LR LR QVL SN LL D NAL K HAAKA ---------- G E ITVT L SEG - GEL TL TVE D N GIG IPPE DL ------- P R IFEP - F S 61
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063728714 107 E alqag AD VSMI G QF G V G FYSAYLVA E KV vvttkhnddeqyvwesqa GG SF TV TRDV dgepl G R GT KI TL F L KDD Q 182
Cdd:pfam02518 62 T ----- AD KRGG G GT G L G LSIVRKLV E LL ------------------ GG TI TV ESEP ----- G G GT TV TL T L PLA Q 109
HATPase_c_3
pfam13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ...
29-146
3.06e-04
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain]
Cd Length: 135
Bit Score: 41.16
E-value: 3.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 29 E IF L R ELI S NS S DA ldki RFESLT dkskldgqpelf I RLVPDKSNK T - LS I I D S G I GM TKAD L V N N L G t I A R S GTK efme 107
Cdd:pfam13589 2 E GA L A ELI D NS I DA ---- DATNIK ------------ I EVNKNRGGG T e IV I E D D G H GM SPEE L I N A L R - L A T S AKE ---- 60
90 100 110 120
....*....|....*....|....*....|....*....|
gi 1063728714 108 alq A GADVSMI G QF G V G FYS A Y L V - AE K VV VT T K HNDDEQ 146
Cdd:pfam13589 61 --- A KRGSTDL G RY G I G LKL A S L S l GA K LT VT S K KEGKSS 97
HATPase_MORC-like
cd16931 Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger ...
32-141
7.04e-03
Histidine kinase-like ATPase domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domain of human microrchidia (MORC) family CW-type zinc finger proteins MORC1-4, and related domains. In addition to the HATPase domain, MORC family proteins have a CW-type zinc finger domain containing four conserved cysteines and two conserved tryptophans, and coiled-coil domains at the carboxy-terminus. MORC1 has cross-species differential methylation in association with early life stress, and genome-wide association with major depressive disorder (MDD). MORC2 is involved in several nuclear processes, including transcription modulation and DNA damage repair, and exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY. MORC3 regulates p53, and is an antiviral factor which plays an important role during HSV-1 and HCMV infection, and is a positive regulator of influenza virus transcription. MORC4 is highly expressed in a subset of diffuse large B-cell lymphomas and has potential as a lymphoma biomarker.
Pssm-ID: 340408 [Multi-domain]
Cd Length: 118
Bit Score: 37.00
E-value: 7.04e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063728714 32 LR EL IS N SS DA ldkirfeslt D KSK LD gqpe L FI RLVPDKSNKT - LS II D S G I GMT KADLVNNLG tiarsgtke F MEALQ 110
Cdd:cd16931 16 VA EL VD N AR DA ---------- D ATR LD ---- I FI DDINLLRGGF m LS FL D D G N GMT PEEAHHMIS --------- F GFSDK 72
90 100 110
....*....|....*....|....*....|..
gi 1063728714 111 AGA D VSM IG QF G V GF Y S - AYLVAEK V V V T TK H 141
Cdd:cd16931 73 RSD D HDH IG RY G N GF K S g SMRLGRD V I V F TK K 104
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
