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Conserved domains on  [gi|15596144|ref|NP_249638|]
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DNA replication initiation factor [Pseudomonas aeruginosa PAO1]

Protein Classification

DnaA regulatory inactivator Hda( domain architecture ID 11496820)

DnaA regulatory inactivator Hda mediates the interactions of DNA replication initiator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN)

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 5-233 9.15e-111

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


:

Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 317.21  E-value: 9.15e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144     5 QLPLSVRLRDDATFANYYPGANAAALGYVERLceaEAGWAESLIYLWGHDGVGRSHLLQAACLRFEQFEERTIYLPMADL 84
Cdd:TIGR03420   1 QLPLDVGLPDDPTFDNFYAGGNAELLAALRQL---AAGKGDRFLYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAEL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    85 VQYGPEIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELQVKLPDLKSRLTMALIFQLH 164
Cdd:TIGR03420  78 AQADPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLP 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15596144   165 GLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETLG 233
Cdd:TIGR03420 158 PLSDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
 
Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 5-233 9.15e-111

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 317.21  E-value: 9.15e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144     5 QLPLSVRLRDDATFANYYPGANAAALGYVERLceaEAGWAESLIYLWGHDGVGRSHLLQAACLRFEQFEERTIYLPMADL 84
Cdd:TIGR03420   1 QLPLDVGLPDDPTFDNFYAGGNAELLAALRQL---AAGKGDRFLYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAEL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    85 VQYGPEIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELQVKLPDLKSRLTMALIFQLH 164
Cdd:TIGR03420  78 AQADPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLP 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15596144   165 GLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETLG 233
Cdd:TIGR03420 158 PLSDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
PRK08084 PRK08084
DnaA inactivator Hda;
3-233 6.06e-90

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 264.62  E-value: 6.06e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    3 PIQLPLSVRLRDDATFANYYPGANAAALGYVERLCEAEAGwaeSLIYLWGHDGVGRSHLLQAACLRFEQFEERTIYLPMA 82
Cdd:PRK08084   6 PAQLSLPLYLPDDETFASFYPGDNDSLLAALQNALRQEHS---GYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVPLD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   83 DLVQYGPEIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGR-RLLLAASKSPRELQVKLPDLKSRLTMALIF 161
Cdd:PRK08084  83 KRAWFVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRtRLLITGDRPPRQLNLGLPDLASRLDWGQIY 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15596144  162 QLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETLG 233
Cdd:PRK08084 163 KLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILK 234
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
12-233 1.40e-49

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 164.21  E-value: 1.40e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144  12 LRDDATFANYYPG-ANAAALGYVERLCEAeAGWAESLIYLWGHDGVGRSHLLQAAC--LRFEQFEERTIYLP----MADL 84
Cdd:COG0593   1 LNPRYTFDNFVVGpSNRLAHAAALAVAEW-PGKAYNPLFLYGGVGLGKTHLLHAIGneALENNPGARVVYLTaeefTNDF 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144  85 VQY-----GPEIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELQVKLPDLKSRLTMAL 159
Cdd:COG0593  80 INAirnntIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGL 159

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15596144 160 IFQLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETLG 233
Cdd:COG0593 160 VVDIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLK 233
Bac_DnaA pfam00308
Bacterial dnaA protein;
12-205 2.78e-19

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 82.76  E-value: 2.78e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    12 LRDDATFANYYPGA-NAAALGYVERLCEAEAGWAESLiYLWGHDGVGRSHLLQAACLRFEQF--EERTIYLP-------M 81
Cdd:pfam00308   1 LNPRYTFENFVIGPsNRFAHAAALTVAKAPGKAYNPL-FIYGGVGLGKTHLLHAIGNYALQNapNLRVVYLTaeeflndF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    82 ADLVQYGP--EIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELqVKLPD-LKSRLTMA 158
Cdd:pfam00308  80 VDAIRDNKtnQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKEL-EELEDrLRSRFQWG 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 15596144   159 LIFQLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSL 205
Cdd:pfam00308 159 LVTDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVREL 205
 
Name Accession Description Interval E-value
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 5-233 9.15e-111

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 317.21  E-value: 9.15e-111
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144     5 QLPLSVRLRDDATFANYYPGANAAALGYVERLceaEAGWAESLIYLWGHDGVGRSHLLQAACLRFEQFEERTIYLPMADL 84
Cdd:TIGR03420   1 QLPLDVGLPDDPTFDNFYAGGNAELLAALRQL---AAGKGDRFLYLWGESGSGKSHLLQAACAAAEERGKSAIYLPLAEL 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    85 VQYGPEIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELQVKLPDLKSRLTMALIFQLH 164
Cdd:TIGR03420  78 AQADPEVLEGLEQADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPLRLPDLRTRLAWGLVFQLP 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15596144   165 GLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETLG 233
Cdd:TIGR03420 158 PLSDEEKIAALQSRAARRGLQLPDEVADYLLRHGSRDMGSLMALLDALDRASLAAKRKITIPFVKEVLA 226
PRK08084 PRK08084
DnaA inactivator Hda;
3-233 6.06e-90

DnaA inactivator Hda;


Pssm-ID: 181224 [Multi-domain]  Cd Length: 235  Bit Score: 264.62  E-value: 6.06e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    3 PIQLPLSVRLRDDATFANYYPGANAAALGYVERLCEAEAGwaeSLIYLWGHDGVGRSHLLQAACLRFEQFEERTIYLPMA 82
Cdd:PRK08084   6 PAQLSLPLYLPDDETFASFYPGDNDSLLAALQNALRQEHS---GYIYLWSREGAGRSHLLHAACAELSQRGRAVGYVPLD 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   83 DLVQYGPEIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGR-RLLLAASKSPRELQVKLPDLKSRLTMALIF 161
Cdd:PRK08084  83 KRAWFVPEVLEGMEQLSLVCIDNIECIAGDELWEMAIFDLYNRILESGRtRLLITGDRPPRQLNLGLPDLASRLDWGQIY 162

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15596144  162 QLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETLG 233
Cdd:PRK08084 163 KLQPLSDEEKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIPFVKEILK 234
PRK08903 PRK08903
DnaA regulatory inactivator Hda; Validated
 5-232 4.55e-52

DnaA regulatory inactivator Hda; Validated


Pssm-ID: 236347 [Multi-domain]  Cd Length: 227  Bit Score: 168.23  E-value: 4.55e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    5 QLPLSVRLRDDATFANYYPGANAAAlgyVERLCEAEAGWA-ESLIYLWGHDGVGRSHLLQAACLRFEQFEERTIYLPMAD 83
Cdd:PRK08903   4 QLTLDLGPPPPPTFDNFVAGENAEL---VARLRELAAGPVaDRFFYLWGEAGSGRSHLLQALVADASYGGRNARYLDAAS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   84 lvqyGPEIFDDLEQCELVCIDDLDVLvgkREWEE-GLFHLFNRLRDTGR-RLLLAASKSPRELQVKlPDLKSRLTMALIF 161
Cdd:PRK08903  81 ----PLLAFDFDPEAELYAVDDVERL---DDAQQiALFNLFNRVRAHGQgALLVAGPAAPLALPLR-EDLRTRLGWGLVY 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15596144  162 QLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETL 232
Cdd:PRK08903 153 ELKPLSDADKIAALKAAAAERGLQLADEVPDYLLTHFRRDMPSLMALLDALDRYSLEQKRPVTLPLLREML 223
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
12-233 1.40e-49

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 164.21  E-value: 1.40e-49
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144  12 LRDDATFANYYPG-ANAAALGYVERLCEAeAGWAESLIYLWGHDGVGRSHLLQAAC--LRFEQFEERTIYLP----MADL 84
Cdd:COG0593   1 LNPRYTFDNFVVGpSNRLAHAAALAVAEW-PGKAYNPLFLYGGVGLGKTHLLHAIGneALENNPGARVVYLTaeefTNDF 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144  85 VQY-----GPEIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELQVKLPDLKSRLTMAL 159
Cdd:COG0593  80 INAirnntIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWGL 159

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15596144 160 IFQLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETLG 233
Cdd:COG0593 160 VVDIQPPDLETRIAILRKKAADRGLELPDEVLEYLARRIERNVRELEGALNRLDAYALLTGRPITLELAREVLK 233
Bac_DnaA pfam00308
Bacterial dnaA protein;
12-205 2.78e-19

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 82.76  E-value: 2.78e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    12 LRDDATFANYYPGA-NAAALGYVERLCEAEAGWAESLiYLWGHDGVGRSHLLQAACLRFEQF--EERTIYLP-------M 81
Cdd:pfam00308   1 LNPRYTFENFVIGPsNRFAHAAALTVAKAPGKAYNPL-FIYGGVGLGKTHLLHAIGNYALQNapNLRVVYLTaeeflndF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    82 ADLVQYGP--EIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELqVKLPD-LKSRLTMA 158
Cdd:pfam00308  80 VDAIRDNKtnQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKEL-EELEDrLRSRFQWG 158

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 15596144   159 LIFQLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSL 205
Cdd:pfam00308 159 LVTDIEPPDLETRLAILRKKAEAEGIEIPPEVLNFIAQRVTDNVREL 205
PRK09087 PRK09087
hypothetical protein; Validated
 2-232 3.28e-17

hypothetical protein; Validated


Pssm-ID: 169652 [Multi-domain]  Cd Length: 226  Bit Score: 77.41  E-value: 3.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    2 KPIQLPL-----SVRLRDDATFAnyypGANAAALGYVERLCEaeagWAESLIYLWGHDGVGRSHLL-----QAACLRFEQ 71
Cdd:PRK09087   4 APEQLPLnfshdPAYGRDDLLVT----ESNRAAVSLVDHWPN----WPSPVVVLAGPVGSGKTHLAsiwreKSDALLIHP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   72 FEertIYLPMADLVQYGPEIFDDLEQCElvcIDdldvlvgkrewEEGLFHLFNRLRDTGRRLLLAASKSPRELQVKLPDL 151
Cdd:PRK09087  76 NE---IGSDAANAAAEGPVLIEDIDAGG---FD-----------ETGLFHLINSVRQAGTSLLMTSRLWPSSWNVKLPDL 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144  152 KSRLTMALIFQLhGLSDEDKLRAL--QLRASRRgLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLK 229
Cdd:PRK09087 139 KSRLKAATVVEI-GEPDDALLSQVifKLFADRQ-LYVDPHVVYYLVSRMERSLFAAQTIVDRLDRLALERKSRITRALAA 216


                 ...
gi 15596144  230 ETL 232
Cdd:PRK09087 217 EVL 219
PRK12422 PRK12422
chromosomal replication initiator protein DnaA;
48-232 2.99e-16

chromosomal replication initiator protein DnaA;


Pssm-ID: 183521 [Multi-domain]  Cd Length: 445  Bit Score: 76.80  E-value: 2.99e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   48 IYLWGHDGVGRSHLLQAACLRFEQFEERTIYLpmadlvqyGPEIFDD-----------------LEQCELVCIDDLDVLV 110
Cdd:PRK12422 144 IYLFGPEGSGKTHLMQAAVHALRESGGKILYV--------RSELFTEhlvsairsgemqrfrqfYRNVDALFIEDIEVFS 215

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144  111 GKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELQVKLPDLKSRLTMALIFQLHGLSDEDKLRALQLRASRRGLHLTDEV 190
Cdd:PRK12422 216 GKGATQEEFFHTFNSLHTEGKLIVISSTCAPQDLKAMEERLISRFEWGIAIPLHPLTKEGLRSFLERKAEALSIRIEETA 295

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 15596144  191 GRFILNRGSRSMNSLFDLLEQLdrASLQAQRKLTIPFLKETL 232
Cdd:PRK12422 296 LDFLIEALSSNVKSLLHALTLL--AKRVAYKKLSHQLLYVDD 335
dnaA PRK00149
chromosomal replication initiator protein DnaA;
10-194 7.33e-15

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 72.86  E-value: 7.33e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   10 VRLRDDATFANYYPG-----ANAAALgyveRLCEAEAGwAESLIYLWGHDGVGRSHLLQAAC--LRFEQFEERTIYLP-- 80
Cdd:PRK00149  64 LQLNPKYTFDNFVVGksnrlAHAAAL----AVAENPGK-AYNPLFIYGGVGLGKTHLLHAIGnyILEKNPNAKVVYVTse 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   81 --MADLVQYgpeIFDD--------LEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELQvKLPD 150
Cdd:PRK00149 139 kfTNDFVNA---LRNNtmeefkekYRSVDVLLIDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPPKELP-GLEE 214

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 15596144  151 -LKSRLTMALIFQLHGLSDEDKLRALQLRASRRGLHLTDEVGRFI 194
Cdd:PRK00149 215 rLRSRFEWGLTVDIEPPDLETRIAILKKKAEEEGIDLPDEVLEFI 259
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 2-194 8.25e-15

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 72.56  E-value: 8.25e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144     2 KPIQLPLSVRLRDDATFANYYPG-----ANAAALGYVErlceaEAGWAESLIYLWGHDGVGRSHLLQAACLRF-EQFEER 75
Cdd:TIGR00362  94 APAPPSSASGLNPKYTFDNFVVGksnrlAHAAALAVAE-----NPGKAYNPLFIYGGVGLGKTHLLHAIGNEIlENNPNA 168

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    76 TI-YLP----MADLV-----QYGPEIFDDLEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPRELQ 145
Cdd:TIGR00362 169 KVlYVSsekfTNDFVnalrnNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHENNKQIVLTSDRPPKELP 248

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 15596144   146 vKLPD-LKSRLTMALIFQLHGLSDEDKLRALQLRASRRGLHLTDEVGRFI 194
Cdd:TIGR00362 249 -GLEDrLRSRFEWGLVVDIEPPDLETRLAILQKKAEEEGLELPDEVLEFI 297
PRK06620 PRK06620
hypothetical protein; Validated
 92-232 4.83e-14

hypothetical protein; Validated


Pssm-ID: 168630  Cd Length: 214  Bit Score: 68.72  E-value: 4.83e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   92 FDD--LEQCELVCIDDLDvlvgkrEWEE-GLFHLFNRLRDTGRRLLLAASKSPRELqvKLPDLKSRLTMALIFQLHGLSD 168
Cdd:PRK06620  78 FNEeiLEKYNAFIIEDIE------NWQEpALLHIFNIINEKQKYLLLTSSDKSRNF--TLPDLSSRIKSVLSILLNSPDD 149

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15596144  169 EdKLRALQLRA-SRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASLQAQRKLTIPFLKETL 232
Cdd:PRK06620 150 E-LIKILIFKHfSISSVTISRQIIDFLLVNLPREYSKIIEILENINYFALISKRKITISLVKEVL 213
dnaA PRK14086
chromosomal replication initiator protein DnaA;
9-205 5.11e-09

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 55.99  E-value: 5.11e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144    9 SVRLRDDATFANYYPG-----ANAAALGyverLCEAEAGwAESLIYLWGHDGVGRSHLLQAAC-----------LRFEQF 72
Cdd:PRK14086 278 TARLNPKYTFDTFVIGasnrfAHAAAVA----VAEAPAK-AYNPLFIYGESGLGKTHLLHAIGhyarrlypgtrVRYVSS 352

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596144   73 EERTiylpmadlVQYGPEIFDD--------LEQCELVCIDDLDVLVGKREWEEGLFHLFNRLRDTGRRLLLAASKSPREL 144
Cdd:PRK14086 353 EEFT--------NEFINSIRDGkgdsfrrrYREMDILLVDDIQFLEDKESTQEEFFHTFNTLHNANKQIVLSSDRPPKQL 424

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15596144  145 qVKLPD-LKSRLTMALIFQLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSL 205
Cdd:PRK14086 425 -VTLEDrLRNRFEWGLITDVQPPELETRIAILRKKAVQEQLNAPPEVLEFIASRISRNIREL 485
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
 160-233 9.09e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 36.67  E-value: 9.09e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15596144  160 IFQLHGLSDEDKLRALQLRASRRGLHLTDEVGRFILNRGSRSMNSLFDLLEQLDRASlqaQRKLTIPFLKETLG 233
Cdd:PRK14962 170 VIEFRNISDELIIKRLQEVAEAEGIEIDREALSFIAKRASGGLRDALTMLEQVWKFS---EGKITLETVHEALG 240
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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