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Concise Results
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Full Results
chaperone protein HtpG [Pseudomonas aeruginosa PAO1]
Protein Classification
Hsp90 family chaperone protein ( domain architecture ID 11480452 )
Hsp90 (heat shock protein 90) family chaperone protein, such as molecular chaperone HtpG (high-temperature protein G) that facilitates the folding and conformational changes of a wide array of proteins
List of domain hits
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
5-634
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 1090.15
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 5 TQK ET LG FQ T EVKQLLHLMIHSLYSNKEIFLRELISNASDA A DKLRFEAL AN P E L L EG GAE LKIR V SFDKEA N T V T LE DN 84
Cdd:PRK05218 1 MAM ET GE FQ A EVKQLLHLMIHSLYSNKEIFLRELISNASDA I DKLRFEAL TD P A L Y EG DGD LKIR I SFDKEA R T L T IS DN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 85 GIGM S RE D V VTH LGTIAKSGT AD FL KN L S GDQKKDS H LIGQFGVGFYSAF I VADKV D V YS R R AG q PA S E G V H W S S K GEGE 164
Cdd:PRK05218 81 GIGM T RE E V IEN LGTIAKSGT KE FL EK L K GDQKKDS Q LIGQFGVGFYSAF M VADKV T V IT R S AG - PA A E A V R W E S D GEGE 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 165 FDVAT I D K P ERGT R I V LHLK KG E E EF A D G WR L R NV IKKYSD H I AL PI E L P KE fhgeeadkpaep E W ET V N R ASALWTR PR 244
Cdd:PRK05218 160 YTIEE I E K E ERGT E I T LHLK ED E D EF L D E WR I R SI IKKYSD F I PV PI K L E KE ------------ E E ET I N S ASALWTR SK 227
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 245 A E VK DEEY Q EFYKH V AHDF EN PL S W S HN K VEG KL EYT S LLY V P GR APFDL YH R EAPR GLKLYV Q RVFIMD Q A D E F LP L YL 324
Cdd:PRK05218 228 S E IT DEEY K EFYKH L AHDF DD PL F W I HN N VEG PF EYT G LLY I P KK APFDL FN R DRKG GLKLYV K RVFIMD D A E E L LP E YL 307
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 325 RF I KGV V DS N DL S LNVSREILQ K D P V IDSMKS A L TK R VLD M LEKLAKN EP E Q Y KT FWK N FG Q VLKEG PA EDF G N K EK I A G 404
Cdd:PRK05218 308 RF V KGV I DS E DL P LNVSREILQ E D R V VKKIRK A I TK K VLD E LEKLAKN DR E K Y EK FWK E FG P VLKEG LY EDF A N R EK L A K 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 405 LLRFAST GD dsg EQS V A LA D Y IG RMKEGQ D KIYY L TG E S YSQV KNSPHLE V F R KKGIEVLLLTD R IDE WLM SYL P EFDGK 484
Cdd:PRK05218 388 LLRFAST HE --- GKY V S LA E Y VE RMKEGQ K KIYY I TG D S REAA KNSPHLE L F K KKGIEVLLLTD P IDE FWI SYL E EFDGK 464
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 485 Q F VD VARGDLDLG SL D s EE D K KAQ EE VAKSKEG L I ERLK KV L DEQ V SE VR V SHRLTDSPA I L AIG E Q D LGL QM RQI L E A S 564
Cdd:PRK05218 465 P F KS VARGDLDLG KE D - EE E K EEK EE AEEEFKP L L ERLK EA L GDK V KD VR L SHRLTDSPA C L VAD E G D MST QM EKL L K A A 543
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 565 GQ K VP D SKPI F EINP Q HPL IE KL DA E P DE DR F GE L SHI L F DQA A LA A G D SL K DP G A Y V R RLN K LL VE L S A 634
Cdd:PRK05218 544 GQ E VP E SKPI L EINP N HPL VK KL AD E A DE AK F KD L AEL L Y DQA L LA E G G SL E DP A A F V K RLN E LL LK L L A 613
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
5-634
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 1090.15
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 5 TQK ET LG FQ T EVKQLLHLMIHSLYSNKEIFLRELISNASDA A DKLRFEAL AN P E L L EG GAE LKIR V SFDKEA N T V T LE DN 84
Cdd:PRK05218 1 MAM ET GE FQ A EVKQLLHLMIHSLYSNKEIFLRELISNASDA I DKLRFEAL TD P A L Y EG DGD LKIR I SFDKEA R T L T IS DN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 85 GIGM S RE D V VTH LGTIAKSGT AD FL KN L S GDQKKDS H LIGQFGVGFYSAF I VADKV D V YS R R AG q PA S E G V H W S S K GEGE 164
Cdd:PRK05218 81 GIGM T RE E V IEN LGTIAKSGT KE FL EK L K GDQKKDS Q LIGQFGVGFYSAF M VADKV T V IT R S AG - PA A E A V R W E S D GEGE 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 165 FDVAT I D K P ERGT R I V LHLK KG E E EF A D G WR L R NV IKKYSD H I AL PI E L P KE fhgeeadkpaep E W ET V N R ASALWTR PR 244
Cdd:PRK05218 160 YTIEE I E K E ERGT E I T LHLK ED E D EF L D E WR I R SI IKKYSD F I PV PI K L E KE ------------ E E ET I N S ASALWTR SK 227
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 245 A E VK DEEY Q EFYKH V AHDF EN PL S W S HN K VEG KL EYT S LLY V P GR APFDL YH R EAPR GLKLYV Q RVFIMD Q A D E F LP L YL 324
Cdd:PRK05218 228 S E IT DEEY K EFYKH L AHDF DD PL F W I HN N VEG PF EYT G LLY I P KK APFDL FN R DRKG GLKLYV K RVFIMD D A E E L LP E YL 307
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 325 RF I KGV V DS N DL S LNVSREILQ K D P V IDSMKS A L TK R VLD M LEKLAKN EP E Q Y KT FWK N FG Q VLKEG PA EDF G N K EK I A G 404
Cdd:PRK05218 308 RF V KGV I DS E DL P LNVSREILQ E D R V VKKIRK A I TK K VLD E LEKLAKN DR E K Y EK FWK E FG P VLKEG LY EDF A N R EK L A K 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 405 LLRFAST GD dsg EQS V A LA D Y IG RMKEGQ D KIYY L TG E S YSQV KNSPHLE V F R KKGIEVLLLTD R IDE WLM SYL P EFDGK 484
Cdd:PRK05218 388 LLRFAST HE --- GKY V S LA E Y VE RMKEGQ K KIYY I TG D S REAA KNSPHLE L F K KKGIEVLLLTD P IDE FWI SYL E EFDGK 464
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 485 Q F VD VARGDLDLG SL D s EE D K KAQ EE VAKSKEG L I ERLK KV L DEQ V SE VR V SHRLTDSPA I L AIG E Q D LGL QM RQI L E A S 564
Cdd:PRK05218 465 P F KS VARGDLDLG KE D - EE E K EEK EE AEEEFKP L L ERLK EA L GDK V KD VR L SHRLTDSPA C L VAD E G D MST QM EKL L K A A 543
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 565 GQ K VP D SKPI F EINP Q HPL IE KL DA E P DE DR F GE L SHI L F DQA A LA A G D SL K DP G A Y V R RLN K LL VE L S A 634
Cdd:PRK05218 544 GQ E VP E SKPI L EINP N HPL VK KL AD E A DE AK F KD L AEL L Y DQA L LA E G G SL E DP A A F V K RLN E LL LK L L A 613
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
5-634
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 1040.08
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 5 TQ KET LG FQ T EVKQLL H LMIHSLYSNKEIFLRELISNASDA A DKLRF E AL AN PEL L E GGAE LKIR VSF DKEA N T V T LE DN 84
Cdd:COG0326 1 MA KET GE FQ A EVKQLL D LMIHSLYSNKEIFLRELISNASDA I DKLRF L AL TD PEL K E EDGD LKIR IEV DKEA K T L T IS DN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 85 GIGM S RE D V VTH LGTIAKSGT AD FL KN L S GDQKKDS H LIGQFGVGFYSAF I VADKV D V YS R R AG QP A s E G V H W S S K G E GE 164
Cdd:COG0326 81 GIGM T RE E V IEN LGTIAKSGT RE FL EK L K GDQKKDS D LIGQFGVGFYSAF M VADKV E V VT R S AG ED A - E A V R W E S D G D GE 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 165 FDVATID K P ERGT R I V LHLK KGE EEF ADG WRLR NV IKKYSD H I AL PI ELPK E fhgeead KPAEP E W ET V N R A S ALWTR PR 244
Cdd:COG0326 160 YTIEEAE K A ERGT E I T LHLK EDA EEF LEE WRLR EI IKKYSD F I PV PI KMEG E ------- EEETE E D ET I N S A T ALWTR SK 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 245 A E VK DEEY Q EFYKH VA HDFE N PL S W S H NK VEG KL EYT S LLY V P GR APFDLY H R EAPR G L KLYV Q RVFIMD Q A DEF LP L YL 324
Cdd:COG0326 233 S E IT DEEY K EFYKH LF HDFE D PL F W I H LN VEG PF EYT G LLY I P KK APFDLY D R DRKG G I KLYV K RVFIMD D A EDL LP E YL 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 325 RF IK GVVDS N DL S LNVSREILQ K D PVIDSMKS A L TK R VLD M LEKLAKN EP E Q Y KT FWK N FG Q VLKEG PA EDF G N K EKIA G 404
Cdd:COG0326 313 RF VR GVVDS P DL P LNVSREILQ E D RQLKKIRK A I TK K VLD E LEKLAKN DR E K Y EK FWK E FG L VLKEG AL EDF K N R EKIA D 392
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 405 LLRF A ST GDD sge QS V A LA D Y IG RMKEGQ D KIYY L TGES YSQVKN SPHLE V F RK KGIEVLLLTD R IDE W L M S Y L P EFDGK 484
Cdd:COG0326 393 LLRF E ST KEG --- GY V T LA E Y VE RMKEGQ K KIYY I TGES REAAEQ SPHLE I F KA KGIEVLLLTD P IDE F L I S H L E EFDGK 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 485 Q F VD V AR GDLD lgs LD SE E D KK AQ EE VAKSKEG L I ER L K KV L DEQ V SE VRVS H RLTDSPA I L AIG E Q D LGLQ M RQI L E A S 564
Cdd:COG0326 470 K F KS V DS GDLD --- LD KL E E KK ES EE EEEEFKP L L ER F K EA L GDK V KD VRVS A RLTDSPA C L VAD E G D MSRR M EKM L K A M 546
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 565 GQ KV P DS KPI F EINP Q HPL IE KL D AE P DE DR F GE L SHI L F DQA A LA A G DS L K DP G A Y V R RLNKLL VELSA 634
Cdd:COG0326 547 GQ DM P EA KPI L EINP N HPL VK KL A AE E DE EL F KD L AEL L Y DQA L LA E G GL L E DP A A F V K RLNKLL EKALG 616
HSP90
pfam00183 Hsp90 protein;
189-629
2.95e-157
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 462.02
E-value: 2.95e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 189 E FADGWRLRNVI KKYS DH I AL PI E L ------ PK E FHG EE ADKPA E P ------------------------------ EWE T 232
Cdd:pfam00183 1 E YLEEKKIKELV KKYS EF I NF PI Y L wvekee EV E VPD EE EEEEE E E eeeedddpkveeedeeeekkktkkvketvw EWE L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 233 V N RASAL WTR PRA EV KD EEY Q EFYK HVAH D F E N PL SWS H NK VEG KL E YT SLL YV P G RAPFDL YHREAPR - GL KLYV Q RVF 311
Cdd:pfam00183 81 L N KTKPI WTR NPK EV TE EEY A EFYK SLSK D W E D PL AVK H FS VEG EV E FK SLL FI P K RAPFDL FENKKKK n NI KLYV R RVF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 312 I M D QADEFL P L YL R F I KGVVDS N DL S LNVSRE I LQ KDPVIDSM K SA L TKRV LDM LEKL A KNE p E Q YK T FWK N FG QV LK E G 391
Cdd:pfam00183 161 I T D DFEDLI P E YL N F V KGVVDS D DL P LNVSRE T LQ QNKILKVI K KK L VRKA LDM FKEI A EEK - E D YK K FWK E FG KN LK L G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 392 PA ED FG N KE K I A G LLRF A S T gd D SG EQSVA L A DY IG RMKEGQ DK IYY L TGES YSQ V K NSP H LE VFR KKG I EVL L LTD R ID 471
Cdd:pfam00183 240 II ED SS N RN K L A K LLRF Y S S -- K SG DELTS L D DY VS RMKEGQ KH IYY I TGES KEE V E NSP F LE RLK KKG Y EVL Y LTD P ID 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 472 E WLMSY L P EFDGK QF V D VA RGD L D L G sl DS EE D KK AQ EE VA K SK E G L IER LK K VL DEQ V SE V R VS H RL T DSP AI L AIGEQ 551
Cdd:pfam00183 318 E YAVQQ L K EFDGK KL V N VA KEG L E L E -- ED EE E KK KD EE LK K EF E P L TKW LK D VL GDK V EK V V VS N RL V DSP CV L VTSQY 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 552 DLGLQ M RQ I LE A - SGQ K VPD ------ SK PIF EINP Q HP L I EK L ---- D A EP D EDRFGE L SHI L FDQ A A L AA G D SL K DP GA 620
Cdd:pfam00183 396 GWSAN M ER I MK A q ALR K DSS mssyms SK KTL EINP R HP I I KE L lkrv E A DK D DKTAKD L ALL L YET A L L RS G F SL E DP AS 475
....*....
gi 15596793 621 YVR R LNKL L 629
Cdd:pfam00183 476 FAS R IYRM L 484
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
17-207
6.59e-103
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 310.22
E-value: 6.59e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 17 K QLL H L M IHSLYSNKEIFLRELISNASDA A DKLR FEA L AN P E LL EGGA EL K IR V S F DKE AN T V T LE D N GIGM SR E DVVTH 96
Cdd:cd16927 1 N QLL D L I IHSLYSNKEIFLRELISNASDA L DKLR YLS L TD P S LL DDDP EL E IR I S P DKE NR T L T IS D T GIGM TK E ELINN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 97 LGTIA K SGT AD FL KN L S g DQK KDS H LIGQFGVGFYSAF I VADKV D V YSRR AG qp AS EG VH W S S K G E G EFDVATIDK - PE R 175
Cdd:cd16927 81 LGTIA R SGT KA FL EA L Q - EGA KDS D LIGQFGVGFYSAF M VADKV T V TTKS AG -- DD EG YR W E S D G G G SYTIEEAEG e LG R 157
170 180 190
....*....|....*....|....*....|..
gi 15596793 176 GT R I V LHLK KGEE EF ADGW R LRNVI KKYSD H I 207
Cdd:cd16927 158 GT K I T LHLK EDAK EF LEEA R IKELV KKYSD F I 189
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
30-185
1.10e-11
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 61.90
E-value: 1.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 30 NKEIF LR ELI SN AS D A A D K LRF E alanpelleg G AELKIRVSF D KEANTV T L EDNG I G MSR ED v VTHL gtiaksgtad F L 109
Cdd:smart00387 1 GDPDR LR QVL SN LL D N A I K YTP E ---------- G GRITVTLER D GDHVEI T V EDNG P G IPP ED - LEKI ---------- F E 59
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15596793 110 KNLSG D qk K D S HL IG QF G V G FYSAFIVADKV dvysrragqpasegvhwsskg E GE FD V at IDK P ER GT RIVLH L KK 185
Cdd:smart00387 60 PFFRT D -- K R S RK IG GT G L G LSIVKKLVELH --------------------- G GE IS V -- ESE P GG GT TFTIT L PL 110
Name
Accession
Description
Interval
E-value
PRK05218
PRK05218 heat shock protein 90; Provisional
5-634
0e+00
heat shock protein 90; Provisional
Pssm-ID: 235366 [Multi-domain]
Cd Length: 613
Bit Score: 1090.15
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 5 TQK ET LG FQ T EVKQLLHLMIHSLYSNKEIFLRELISNASDA A DKLRFEAL AN P E L L EG GAE LKIR V SFDKEA N T V T LE DN 84
Cdd:PRK05218 1 MAM ET GE FQ A EVKQLLHLMIHSLYSNKEIFLRELISNASDA I DKLRFEAL TD P A L Y EG DGD LKIR I SFDKEA R T L T IS DN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 85 GIGM S RE D V VTH LGTIAKSGT AD FL KN L S GDQKKDS H LIGQFGVGFYSAF I VADKV D V YS R R AG q PA S E G V H W S S K GEGE 164
Cdd:PRK05218 81 GIGM T RE E V IEN LGTIAKSGT KE FL EK L K GDQKKDS Q LIGQFGVGFYSAF M VADKV T V IT R S AG - PA A E A V R W E S D GEGE 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 165 FDVAT I D K P ERGT R I V LHLK KG E E EF A D G WR L R NV IKKYSD H I AL PI E L P KE fhgeeadkpaep E W ET V N R ASALWTR PR 244
Cdd:PRK05218 160 YTIEE I E K E ERGT E I T LHLK ED E D EF L D E WR I R SI IKKYSD F I PV PI K L E KE ------------ E E ET I N S ASALWTR SK 227
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 245 A E VK DEEY Q EFYKH V AHDF EN PL S W S HN K VEG KL EYT S LLY V P GR APFDL YH R EAPR GLKLYV Q RVFIMD Q A D E F LP L YL 324
Cdd:PRK05218 228 S E IT DEEY K EFYKH L AHDF DD PL F W I HN N VEG PF EYT G LLY I P KK APFDL FN R DRKG GLKLYV K RVFIMD D A E E L LP E YL 307
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 325 RF I KGV V DS N DL S LNVSREILQ K D P V IDSMKS A L TK R VLD M LEKLAKN EP E Q Y KT FWK N FG Q VLKEG PA EDF G N K EK I A G 404
Cdd:PRK05218 308 RF V KGV I DS E DL P LNVSREILQ E D R V VKKIRK A I TK K VLD E LEKLAKN DR E K Y EK FWK E FG P VLKEG LY EDF A N R EK L A K 387
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 405 LLRFAST GD dsg EQS V A LA D Y IG RMKEGQ D KIYY L TG E S YSQV KNSPHLE V F R KKGIEVLLLTD R IDE WLM SYL P EFDGK 484
Cdd:PRK05218 388 LLRFAST HE --- GKY V S LA E Y VE RMKEGQ K KIYY I TG D S REAA KNSPHLE L F K KKGIEVLLLTD P IDE FWI SYL E EFDGK 464
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 485 Q F VD VARGDLDLG SL D s EE D K KAQ EE VAKSKEG L I ERLK KV L DEQ V SE VR V SHRLTDSPA I L AIG E Q D LGL QM RQI L E A S 564
Cdd:PRK05218 465 P F KS VARGDLDLG KE D - EE E K EEK EE AEEEFKP L L ERLK EA L GDK V KD VR L SHRLTDSPA C L VAD E G D MST QM EKL L K A A 543
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 565 GQ K VP D SKPI F EINP Q HPL IE KL DA E P DE DR F GE L SHI L F DQA A LA A G D SL K DP G A Y V R RLN K LL VE L S A 634
Cdd:PRK05218 544 GQ E VP E SKPI L EINP N HPL VK KL AD E A DE AK F KD L AEL L Y DQA L LA E G G SL E DP A A F V K RLN E LL LK L L A 613
HtpG
COG0326 Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, ...
5-634
0e+00
Molecular chaperone, HSP90 family [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440095 [Multi-domain]
Cd Length: 616
Bit Score: 1040.08
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 5 TQ KET LG FQ T EVKQLL H LMIHSLYSNKEIFLRELISNASDA A DKLRF E AL AN PEL L E GGAE LKIR VSF DKEA N T V T LE DN 84
Cdd:COG0326 1 MA KET GE FQ A EVKQLL D LMIHSLYSNKEIFLRELISNASDA I DKLRF L AL TD PEL K E EDGD LKIR IEV DKEA K T L T IS DN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 85 GIGM S RE D V VTH LGTIAKSGT AD FL KN L S GDQKKDS H LIGQFGVGFYSAF I VADKV D V YS R R AG QP A s E G V H W S S K G E GE 164
Cdd:COG0326 81 GIGM T RE E V IEN LGTIAKSGT RE FL EK L K GDQKKDS D LIGQFGVGFYSAF M VADKV E V VT R S AG ED A - E A V R W E S D G D GE 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 165 FDVATID K P ERGT R I V LHLK KGE EEF ADG WRLR NV IKKYSD H I AL PI ELPK E fhgeead KPAEP E W ET V N R A S ALWTR PR 244
Cdd:COG0326 160 YTIEEAE K A ERGT E I T LHLK EDA EEF LEE WRLR EI IKKYSD F I PV PI KMEG E ------- EEETE E D ET I N S A T ALWTR SK 232
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 245 A E VK DEEY Q EFYKH VA HDFE N PL S W S H NK VEG KL EYT S LLY V P GR APFDLY H R EAPR G L KLYV Q RVFIMD Q A DEF LP L YL 324
Cdd:COG0326 233 S E IT DEEY K EFYKH LF HDFE D PL F W I H LN VEG PF EYT G LLY I P KK APFDLY D R DRKG G I KLYV K RVFIMD D A EDL LP E YL 312
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 325 RF IK GVVDS N DL S LNVSREILQ K D PVIDSMKS A L TK R VLD M LEKLAKN EP E Q Y KT FWK N FG Q VLKEG PA EDF G N K EKIA G 404
Cdd:COG0326 313 RF VR GVVDS P DL P LNVSREILQ E D RQLKKIRK A I TK K VLD E LEKLAKN DR E K Y EK FWK E FG L VLKEG AL EDF K N R EKIA D 392
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 405 LLRF A ST GDD sge QS V A LA D Y IG RMKEGQ D KIYY L TGES YSQVKN SPHLE V F RK KGIEVLLLTD R IDE W L M S Y L P EFDGK 484
Cdd:COG0326 393 LLRF E ST KEG --- GY V T LA E Y VE RMKEGQ K KIYY I TGES REAAEQ SPHLE I F KA KGIEVLLLTD P IDE F L I S H L E EFDGK 469
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 485 Q F VD V AR GDLD lgs LD SE E D KK AQ EE VAKSKEG L I ER L K KV L DEQ V SE VRVS H RLTDSPA I L AIG E Q D LGLQ M RQI L E A S 564
Cdd:COG0326 470 K F KS V DS GDLD --- LD KL E E KK ES EE EEEEFKP L L ER F K EA L GDK V KD VRVS A RLTDSPA C L VAD E G D MSRR M EKM L K A M 546
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 565 GQ KV P DS KPI F EINP Q HPL IE KL D AE P DE DR F GE L SHI L F DQA A LA A G DS L K DP G A Y V R RLNKLL VELSA 634
Cdd:COG0326 547 GQ DM P EA KPI L EINP N HPL VK KL A AE E DE EL F KD L AEL L Y DQA L LA E G GL L E DP A A F V K RLNKLL EKALG 616
PTZ00272
PTZ00272 heat shock protein 83 kDa (Hsp83); Provisional
8-629
2.50e-179
heat shock protein 83 kDa (Hsp83); Provisional
Pssm-ID: 240341
Cd Length: 701
Bit Score: 525.40
E-value: 2.50e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 8 ET LG FQ T E VK QL LH L M I HSL YSNKEIFLRELISNASDA A DK L R FEA L AN P EL L EGGAE L K IRV SF DKE AN T V T L EDNGIG 87
Cdd:PTZ00272 3 ET FA FQ A E IN QL MS L I I NTF YSNKEIFLRELISNASDA C DK I R YQS L TD P SV L GESPR L C IRV VP DKE NK T L T V EDNGIG 82
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 88 M SRE D V V TH LGTIA K SGT AD F LKN L sg DQKK D SHL IGQFGVGFYSA FI VAD K V D V Y S RRA gqp AS E GVH W S S KGE G E F DV 167
Cdd:PTZ00272 83 M TKA D L V NN LGTIA R SGT KA F MEA L -- EAGG D MSM IGQFGVGFYSA YL VAD R V T V T S KNN --- SD E SYV W E S SAG G T F TI 157
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 168 ATIDKPE -- RGTRI V LHLK KGEE E FADGW RL RNV IKK Y S DH I ALP IEL ------ P KE FHG E EADKPA ------- EP ---- 228
Cdd:PTZ00272 158 TSTPESD mk RGTRI T LHLK EDQM E YLEPR RL KEL IKK H S EF I GYD IEL mvektt E KE VTD E DEEDTK kadedge EP kvee 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 229 -------------------- E W E TV N RASA LWTR PRAE V KD EEY QE FYK HVAH D F E N P LSWS H NK VEG K LE YT S LLY VP G 288
Cdd:PTZ00272 238 vkegdegkkkktkkvkevtk E Y E VQ N KHKP LWTR DPKD V TK EEY AA FYK AISN D W E D P AATK H FS VEG Q LE FR S IMF VP K 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 289 RAPFD LYHREAP R - GL KLYV Q RVFIMD QADEFL P LY L R F I KGVVDS N DL S LN V SRE I LQ KDPVIDSMKSALT K RV L D M LE 367
Cdd:PTZ00272 318 RAPFD MFEPNKK R n NI KLYV R RVFIMD NCEDLC P DW L G F V KGVVDS E DL P LN I SRE N LQ QNKILKVIRKNIV K KC L E M FD 397
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 368 KL A K N E p E Q YK T F WKN FG QVL K E G PA ED FG N KE K IAG LLRF A ST gd D SGE QSVA L A DY IG RMK E GQ DK IYY L TG E S YSQV 447
Cdd:PTZ00272 398 EV A E N K - E D YK Q F YEQ FG KNI K L G IH ED TA N RK K LME LLRF Y ST -- E SGE EMTT L K DY VT RMK A GQ KS IYY I TG D S KKKL 474
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 448 KN SP HL E VF R KK G I EVL LL T DR IDE WL M SYLPE F DG K Q F VDVARGDLDLG sl D SEE D K KAQ EE VAKSK E G L IERL K K VL D 527
Cdd:PTZ00272 475 ET SP FI E QA R RR G L EVL FM T EP IDE YV M QQVKD F ED K K F ACLTKEGVHFE -- E SEE E K QQR EE EKAAC E K L CKTM K E VL G 552
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 528 EQ V SE V R VS H RL TD SP A IL AIG E QDLGLQ M R QI L ------ EA S GQKVPD SK PIF E I NP Q HP L I EK L ---- D A EPDEDRFG 597
Cdd:PTZ00272 553 DK V EK V I VS E RL ST SP C IL VTS E FGWSAH M E QI M rnqalr DS S MAQYMM SK KTM E L NP R HP I I KE L rrrv G A DENDKAVK 632
650 660 670
....*....|....*....|....*....|..
gi 15596793 598 E L SHI LFD QAA L AA G DS L K DP GA Y VR R L N KLL 629
Cdd:PTZ00272 633 D L VFL LFD TSL L TS G FQ L E DP TG Y AE R I N RMI 664
HSP90
pfam00183 Hsp90 protein;
189-629
2.95e-157
Hsp90 protein;
Pssm-ID: 459703
Cd Length: 516
Bit Score: 462.02
E-value: 2.95e-157
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 189 E FADGWRLRNVI KKYS DH I AL PI E L ------ PK E FHG EE ADKPA E P ------------------------------ EWE T 232
Cdd:pfam00183 1 E YLEEKKIKELV KKYS EF I NF PI Y L wvekee EV E VPD EE EEEEE E E eeeedddpkveeedeeeekkktkkvketvw EWE L 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 233 V N RASAL WTR PRA EV KD EEY Q EFYK HVAH D F E N PL SWS H NK VEG KL E YT SLL YV P G RAPFDL YHREAPR - GL KLYV Q RVF 311
Cdd:pfam00183 81 L N KTKPI WTR NPK EV TE EEY A EFYK SLSK D W E D PL AVK H FS VEG EV E FK SLL FI P K RAPFDL FENKKKK n NI KLYV R RVF 160
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 312 I M D QADEFL P L YL R F I KGVVDS N DL S LNVSRE I LQ KDPVIDSM K SA L TKRV LDM LEKL A KNE p E Q YK T FWK N FG QV LK E G 391
Cdd:pfam00183 161 I T D DFEDLI P E YL N F V KGVVDS D DL P LNVSRE T LQ QNKILKVI K KK L VRKA LDM FKEI A EEK - E D YK K FWK E FG KN LK L G 239
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 392 PA ED FG N KE K I A G LLRF A S T gd D SG EQSVA L A DY IG RMKEGQ DK IYY L TGES YSQ V K NSP H LE VFR KKG I EVL L LTD R ID 471
Cdd:pfam00183 240 II ED SS N RN K L A K LLRF Y S S -- K SG DELTS L D DY VS RMKEGQ KH IYY I TGES KEE V E NSP F LE RLK KKG Y EVL Y LTD P ID 317
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 472 E WLMSY L P EFDGK QF V D VA RGD L D L G sl DS EE D KK AQ EE VA K SK E G L IER LK K VL DEQ V SE V R VS H RL T DSP AI L AIGEQ 551
Cdd:pfam00183 318 E YAVQQ L K EFDGK KL V N VA KEG L E L E -- ED EE E KK KD EE LK K EF E P L TKW LK D VL GDK V EK V V VS N RL V DSP CV L VTSQY 395
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 552 DLGLQ M RQ I LE A - SGQ K VPD ------ SK PIF EINP Q HP L I EK L ---- D A EP D EDRFGE L SHI L FDQ A A L AA G D SL K DP GA 620
Cdd:pfam00183 396 GWSAN M ER I MK A q ALR K DSS mssyms SK KTL EINP R HP I I KE L lkrv E A DK D DKTAKD L ALL L YET A L L RS G F SL E DP AS 475
....*....
gi 15596793 621 YVR R LNKL L 629
Cdd:pfam00183 476 FAS R IYRM L 484
PTZ00130
PTZ00130 heat shock protein 90; Provisional
8-617
4.98e-133
heat shock protein 90; Provisional
Pssm-ID: 185466 [Multi-domain]
Cd Length: 814
Bit Score: 409.82
E-value: 4.98e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 8 E TLGF QTEV KQ L LHLMIH SLY SN KE I FLRELISNA S DA AD K L RF EA L ANPEL L EGGAE L K IR V S FD KE A N TVTLE D N GIG 87
Cdd:PTZ00130 66 E QHQY QTEV TR L MDIIVN SLY TQ KE V FLRELISNA A DA LE K I RF LS L SDESV L GEEKK L E IR I S AN KE K N ILSIT D T GIG 145
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 88 M SR ED VVTH LGTIAKSGT AD FL KNL S g DQKK D SH LIGQFGVGFYSAF I VADKV D VY SRRAG qpa S E GVH W S S KGEGE F DV 167
Cdd:PTZ00130 146 M TK ED LINN LGTIAKSGT SN FL EAI S - KSGG D MS LIGQFGVGFYSAF L VADKV I VY TKNNN --- D E QYI W E S TADAK F TI 221
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 168 ------ A T I dkp E RGTRI V LHLK KGEEEFADGWR L RNV I K KYS DH I AL PI E L PK E ----------------------- FH 218
Cdd:PTZ00130 222 ykdprg S T L --- K RGTRI S LHLK EDATNLMNDKK L VDL I S KYS QF I QY PI Y L LH E nvyteevladiakemendpnyds VK 298
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 219 G EE A D K P AE --------- PE W ETV N RASAL W T RP RA E VK DE E Y QE F YKHVAHDFEN PL SWS H NKV EG KL E YTS L L Y V P G R 289
Cdd:PTZ00130 299 V EE T D D P NK ktrtvekkv KK W KLM N EQKPI W L RP PK E LT DE D Y KK F FSVLSGFNDE PL YHI H FFA EG EI E FKC L I Y I P S R 378
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 290 AP F --- D L YHRE ap RGL KLYV Q RV FIM D QAD EFLP L Y LR F I KGVVDS N DL S LNVSRE I LQ KDPVIDSMKSALTKRV LD ML 366
Cdd:PTZ00130 379 AP S ind H L FTKQ -- NSI KLYV R RV LVA D EFV EFLP R Y MS F V KGVVDS D DL P LNVSRE Q LQ QNKILKAVSKRIVRKI LD TF 456
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 367 EK L A K ----------------------------- NEP EQ YK TFW K NFGQV LK E G PA ED FG N KE KI AG LL R F AST gdd SGE 417
Cdd:PTZ00130 457 RT L Y K egkknketlraelaketdeekkkeiqkki NEP ST YK LIY K EYRKY LK T G CY ED DI N RN KI VK LL L F KTM --- LHP 533
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 418 Q S VA L AD YI GR MK EG Q DK IYY LT G E SY SQVKNS P H L EV F R KK G I E V LL LT DRI DE WLMSYLP E F DGK Q F VDVAR G DLDLG 497
Cdd:PTZ00130 534 K S IS L DT YI EN MK PD Q KF IYY AS G D SY EYLSKI P Q L QI F K KK N I D V VF LT ESV DE SCVQRVQ E Y DGK K F KSIQK G EITFE 613
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 498 S ld S E ED KK AQ E E V A K SKEG LI ERLKKV L DE Q VSE V RV S H RL T D S P AILAIG E QD L GL QM RQILE ----- ASGQ K VPDSK 572
Cdd:PTZ00130 614 L -- T E DE KK KE E K V K K MYKA LI DVISDT L RN Q IFK V EI S R RL V D A P CAVVST E WG L SG QM EKLMK invnn SDQI K AMSGQ 691
650 660 670 680
....*....|....*....|....*....|....*....|....*....
gi 15596793 573 P I F EINP Q HP ---- L IEKLDAE P DEDRFG E LSH I LFDQ A A LA A G DS L K D 617
Cdd:PTZ00130 692 K I L EINP D HP imid L LKRSVSN P KDSQLT E SIK I IYQS A K LA S G FD L E D 740
HATPase_Hsp90-like
cd16927 Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including ...
17-207
6.59e-103
Histidine kinase-like ATPase domain of human cytosolic Hsp90 and its homologs including Escherichia coli HtpG, and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of 90 kilodalton heat-shock protein (Hsp90) eukaryotic homologs including cytosolic Hsp90, mitochondrial TRAP1 (tumor necrosis factor receptor-associated protein 1), GRP94 (94 kDa glucose-regulated protein) of the endoplasmic reticulum (ER), and chloroplast Hsp90C. It also includes the bacterial homologs of Hsp90, known as HtpG (High temperature protein G). Hsp90 family of chaperones assist other proteins to fold correctly, stabilizes them against heat stress, and aids in protein degradation.
Pssm-ID: 340404 [Multi-domain]
Cd Length: 189
Bit Score: 310.22
E-value: 6.59e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 17 K QLL H L M IHSLYSNKEIFLRELISNASDA A DKLR FEA L AN P E LL EGGA EL K IR V S F DKE AN T V T LE D N GIGM SR E DVVTH 96
Cdd:cd16927 1 N QLL D L I IHSLYSNKEIFLRELISNASDA L DKLR YLS L TD P S LL DDDP EL E IR I S P DKE NR T L T IS D T GIGM TK E ELINN 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 97 LGTIA K SGT AD FL KN L S g DQK KDS H LIGQFGVGFYSAF I VADKV D V YSRR AG qp AS EG VH W S S K G E G EFDVATIDK - PE R 175
Cdd:cd16927 81 LGTIA R SGT KA FL EA L Q - EGA KDS D LIGQFGVGFYSAF M VADKV T V TTKS AG -- DD EG YR W E S D G G G SYTIEEAEG e LG R 157
170 180 190
....*....|....*....|....*....|..
gi 15596793 176 GT R I V LHLK KGEE EF ADGW R LRNVI KKYSD H I 207
Cdd:cd16927 158 GT K I T LHLK EDAK EF LEEA R IKELV KKYSD F I 189
PRK14083
PRK14083 HSP90 family protein; Provisional
12-616
3.42e-44
HSP90 family protein; Provisional
Pssm-ID: 237603 [Multi-domain]
Cd Length: 601
Bit Score: 167.04
E-value: 3.42e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 12 FQ TEVKQLLH L MIHS LYS NKEIFL REL IS NA S DA ADKL R fealanpe L L EGG A ELK IR VS - F D KEAN T VTL EDNGIG MSR 90
Cdd:PRK14083 5 FQ VDLRGVID L LSRH LYS SPRVYV REL LQ NA V DA ITAR R -------- A L DPT A PGR IR IE l T D AGGG T LIV EDNGIG LTE 76
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 91 E D V VTH L G TI AK S GTA D flk NLS G DQKK D sh LI GQFG V G FY S A F I VAD KVD V Y SR R A GQPAS eg V H W SS K GE G EFD V ATI 170
Cdd:PRK14083 77 E E V HEF L A TI GR S SKR D --- ENL G FARN D -- FL GQFG I G LL S C F L VAD EIV V V SR S A KDGPA -- V E W RG K AD G TYS V RKL 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 171 DKPER -- GT RIV L HLKKGE EE FADGWRLRNVI KKY SD hi A LP IEL pk EFH GE E adkpaepew ET VN RASAL WTR PRAE v K 248
Cdd:PRK14083 150 ETERA ep GT TVY L RPRPDA EE WLERETVEELA KKY GS -- L LP VPI -- RVE GE K --------- GG VN ETPPP WTR DYPD - P 215
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 249 DEEYQEFYKHVAHDFEN ------ PL SWSHNKV EG kleyts LL YV - P GRAPFD lyhre A P R GLKL Y VQ R VFIMDQ A DEF LP 321
Cdd:PRK14083 216 ETRREALLAYGEELLGF tpldvi PL DVPSGGL EG ------ VA YV l P YAVSPA ----- A R R KHRV Y LK R MLLSEE A ENL LP 284
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 322 LYLR F IKG VV DSND L SLNV SRE I L QK D PVIDSMKSA L TKRVLDM L EK LA KNE PE QYKTFWKNFGQVL K EGPAE D FGNKEK 401
Cdd:PRK14083 285 DWAF F VRC VV NTDE L RPTA SRE A L YE D DALAAVREE L GEAIRKW L IG LA TTD PE RLRRLLAVHHLGV K ALASH D DELLRL 364
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 402 I AGL L R F AS T gdd S G EQS va LA DYIG R mkeg QDK I Y Y LTG - ESYS Q VK nsphl EVF R KK G IE V LLLTDRI D EW L MSY LP E 480
Cdd:PRK14083 365 I LPW L P F ET T --- D G RMT -- LA EIRR R ---- HGV I R Y TSS v DEFR Q LA ----- PIA R AQ G MG V INGGYTY D SE L LER LP R 430
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 481 FD - G KQFVDVARGD L -- D L GS L DS EE DKKAQ eevakske GLIERLKK VL DEQVSE V RVS H RLTDS - PA ILAIGEQDLGLQ 556
Cdd:PRK14083 431 LR p G LTVERLDPAE L td R L EP L TP EE ELALR -------- PFLAEARE VL APFGCD V VIR H FEPAD l PA LYLHDRAAQHSR 502
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15596793 557 M R ------------ Q IL EASGQKV P DSKPIFEI N PQH PL IEK L DAEP D EDRFGELSHI L FD QA A L AAGDS L K 616
Cdd:PRK14083 503 E R eeaveeaddlwa D IL GSLDESQ P APRARLVL N LRN PL VRR L ATLG D PKLLSRAVEA L YV QA L L LGHRP L R 574
HATPase_c
smart00387 Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
30-185
1.10e-11
Histidine kinase-like ATPases; Histidine kinase-, DNA gyrase B-, phytochrome-like ATPases.
Pssm-ID: 214643 [Multi-domain]
Cd Length: 111
Bit Score: 61.90
E-value: 1.10e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 30 NKEIF LR ELI SN AS D A A D K LRF E alanpelleg G AELKIRVSF D KEANTV T L EDNG I G MSR ED v VTHL gtiaksgtad F L 109
Cdd:smart00387 1 GDPDR LR QVL SN LL D N A I K YTP E ---------- G GRITVTLER D GDHVEI T V EDNG P G IPP ED - LEKI ---------- F E 59
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15596793 110 KNLSG D qk K D S HL IG QF G V G FYSAFIVADKV dvysrragqpasegvhwsskg E GE FD V at IDK P ER GT RIVLH L KK 185
Cdd:smart00387 60 PFFRT D -- K R S RK IG GT G L G LSIVKKLVELH --------------------- G GE IS V -- ESE P GG GT TFTIT L PL 110
HATPase_c
pfam02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the ...
30-184
1.03e-05
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 460579 [Multi-domain]
Cd Length: 109
Bit Score: 44.67
E-value: 1.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 30 NK E IF LR ELI SN AS D A A dk L RFE A lanpelle GGA E LKIRV S f DKEAN T V T L EDNGIG MSR ED vvthlgt IAKSGTA d F L 109
Cdd:pfam02518 1 GD E LR LR QVL SN LL D N A -- L KHA A -------- KAG E ITVTL S - EGGEL T L T V EDNGIG IPP ED ------- LPRIFEP - F S 61
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15596793 110 KNLSGDQ kkdshli G QF G V G FYSAFIVADKVD vysrragqpasegvhwsskge G EFD V AT id K P ER GT RIV L H L K 184
Cdd:pfam02518 62 TADKRGG ------- G GT G L G LSIVRKLVELLG --------------------- G TIT V ES -- E P GG GT TVT L T L P 106
HATPase_TopVIB-like
cd16933 Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family ...
7-195
1.98e-05
Histidine kinase-like ATPase domain of type IIB topoisomerase, Topo VI, subunit B; This family includes the histidine kinase-like ATPase (HATPase) domain of the B subunit of topoisomerase VI (Topo VIB). Topo VI is a heterotetrameric complex composed of two TopVIA and two TopVIB subunits and is categorized as a type II B DNA topoisomerase. It is found in archaea and also in plants. Type II enzymes cleave both strands of a DNA duplex and pass a second duplex through the resulting break in an ATP-dependent mechanism. DNA cleavage by Topo VI generates two-nucleotide 5'-protruding ends.
Pssm-ID: 340410 [Multi-domain]
Cd Length: 203
Bit Score: 45.80
E-value: 1.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 7 KE T LGF QTEVK qllhlmih SLY snke IFL REL IS N AS DA AD klrf EA LAN P EL leggael K IRVS - FD K EANT V TL EDNG 85
Cdd:cd16933 8 KE M LGF DNPIR -------- SLY ---- TTV REL VE N SL DA TE ---- EA GIL P DI ------- K VEIE e IG K DHYK V IV EDNG 64
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 86 I G MSR E D vvthlgt I A K S gtad F L K N L S G DQKKDSHLI GQ F G V G FYS A FI vadkvdv YS R - RA G Q P AS eg VHW S S K GEGE 164
Cdd:cd16933 65 P G IPE E Q ------- I P K V ---- F G K V L Y G SKYHNKQSR GQ Q G L G ISA A VL ------- YS Q m TT G K P VE -- IIS S T K DSNY 124
170 180 190
....*....|....*....|....*....|...
gi 15596793 165 -- FDVAT ID KPERGTR I V lhl K K G E E E FADG W R 195
Cdd:cd16933 125 ay VVKLM ID TDKNEPE I L --- E K E E V E NRYK W H 154
HATPase_MutL-MLH-PMS-like
cd16926 Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, ...
35-94
1.85e-03
Histidine kinase-like ATPase domain of DNA mismatch repair proteins Escherichia coli MutL, human MutL homologs (MLH/ PMS), and related domains; This family includes the histidine kinase-like ATPase (HATPase) domains of Escherichia coli MutL, human MLH1 (mutL homolog 1), human PMS1 (PMS1 homolog 1, mismatch repair system component), human MLH3 (mutL homolog 3), and human PMS2 (PMS1 homolog 2, mismatch repair system component). MutL homologs (MLH/PMS) participate in MMR (DNA mismatch repair), and in addition have role(s) in DNA damage signaling and suppression of homologous recombination (recombination between partially homologous parental DNAs). The primary role of MutL in MMR is to mediate protein-protein interactions during mismatch recognition and strand removal; a ternary complex is formed between MutS, MutL, and the mismatched DNA, which activates the MutH endonuclease.
Pssm-ID: 340403 [Multi-domain]
Cd Length: 188
Bit Score: 39.73
E-value: 1.85e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15596793 35 LR EL IS N AS DA - A DKLRF E alanpe LL EGG AE L k IRV S fdkeantvtle DNG I G M SRED VV 94
Cdd:cd16926 18 VK EL VE N SI DA g A TRIDV E ------ IE EGG LK L - IRV T ----------- DNG S G I SRED LE 60
HATPase_c_3
pfam13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, ...
32-171
8.74e-03
Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; This family represents, additionally, the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.
Pssm-ID: 433332 [Multi-domain]
Cd Length: 135
Bit Score: 36.93
E-value: 8.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15596793 32 E IF L R ELI S N AS DA ADK lrfealanpellegga EL KI R V SFDKEAN T - VTL ED N G I GMS R E DVVTH L G t I A K S GT adflk 110
Cdd:pfam13589 2 E GA L A ELI D N SI DA DAT ---------------- NI KI E V NKNRGGG T e IVI ED D G H GMS P E ELINA L R - L A T S AK ----- 59
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15596793 111 nlsg DQ K KD S HLI G QF G V G FYS A fivadkvdvy S RRA G QPAS egvh WS SK G EG EFDVA T I D 171
Cdd:pfam13589 60 ---- EA K RG S TDL G RY G I G LKL A ---------- S LSL G AKLT ---- VT SK K EG KSSTL T L D 102
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
