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Conserved domains on  [gi|15598385|ref|NP_251879|]
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sugar ABC transporter permease [Pseudomonas aeruginosa PAO1]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-300 4.63e-82

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 250.05  E-value: 4.63e-82
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  11 APVAPRRVSPLDRLQGWLPKLVLAPSVVVVLFCMYGYIGWTLLLSFTNSRFM-PSYKWAGLSQYQRLWDNDRWWVASKNL 89
Cdd:COG1175   2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLgPPPEFVGLDNYARLFTDPRFWNALGNT 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  90 LLFGGSFIAICLVLGVFLAVLLDQRIRREGFIRTLYLYPMALSMIVTGTAWKWLLNPGLG-LDKLLRDWGWEGFrfDWLV 168
Cdd:COG1175  82 LLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGlLNALLGALGLEPI--NWLG 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 169 DPERVVYCLVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFDL 248
Cdd:COG1175 160 DPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDL 239
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|..
gi 15598385 249 VAAMTAGGPGYSSDLPAMFMYAHTFTRGQMGLGAASAMLMLGAVLAIVVPYL 300
Cdd:COG1175 240 VYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQL 291
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-300 4.63e-82

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 250.05  E-value: 4.63e-82
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  11 APVAPRRVSPLDRLQGWLPKLVLAPSVVVVLFCMYGYIGWTLLLSFTNSRFM-PSYKWAGLSQYQRLWDNDRWWVASKNL 89
Cdd:COG1175   2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLgPPPEFVGLDNYARLFTDPRFWNALGNT 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  90 LLFGGSFIAICLVLGVFLAVLLDQRIRREGFIRTLYLYPMALSMIVTGTAWKWLLNPGLG-LDKLLRDWGWEGFrfDWLV 168
Cdd:COG1175  82 LLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGlLNALLGALGLEPI--NWLG 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 169 DPERVVYCLVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFDL 248
Cdd:COG1175 160 DPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDL 239
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|..
gi 15598385 249 VAAMTAGGPGYSSDLPAMFMYAHTFTRGQMGLGAASAMLMLGAVLAIVVPYL 300
Cdd:COG1175 240 VYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQL 291
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
61-303 2.04e-19

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 86.03  E-value: 2.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385   61 FMPSYKWAGLSQYQRLWDNDRWWVASKNLLLFGGSFIAICLVLGVFLAVLLDQRIRREGFIRTLYLYPMALSMIVTGTAW 140
Cdd:PRK10561  32 FGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAALVDYVVRGSRFYQTLMLLPYAVAPAVAAVLW 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  141 KWLLNPGLGL-DKLLRDWgweGFRFDWLVDPERVVYCLVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIY 219
Cdd:PRK10561 112 IFLFNPGRGLiTHFLAEF---GYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRF 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  220 LRIVLPSLRPVFFSALMI-LAHIAIKSFDLVAAMTAGGPGYSSDLPAMFMYAHTFTRGQMGLGAA-SAMLMLGAVLAIVV 297
Cdd:PRK10561 189 FKLALPLIAPVSFFLLVVnLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLSSSAAqSVVLMFLVIVLTVV 268

                 ....*.
gi 15598385  298 PYLYSE 303
Cdd:PRK10561 269 QFRYVE 274
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
90-296 5.16e-07

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 49.20  E-value: 5.16e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  90 LLFGGSFIAICLVLGVFLAVLLDQRIRR-EGFIRTLYLYPMALSMIVTGTAWKWLLnpglgldkllrdwgweGFRFDWLV 168
Cdd:cd06261   5 LLLALIATLLALVLGLLLGIILARKRGKlDRLLRRIIDLLLSLPSLVLGLLLVLLF----------------GVLLGWGI 68
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 169 DPERVVYCLVIAAVWQAsGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFDL 248
Cdd:cd06261  69 LPGLGLPALILALLLIA-PFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFAL 147
                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 15598385 249 VAAMTAGGPGYSSDLPAMFmyahtFTRGQMGLGAASAMLMLGAVLAIV 296
Cdd:cd06261 148 VSFLGGGEAPGPGTGLLLI-----FAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
177-300 5.31e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.14  E-value: 5.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385   177 LVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFDLVAAMTAGG 256
Cdd:pfam00528  55 AIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP 134
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 15598385   257 PGYSSDLPAMFMYAHTFTRGqMGLGAASAMLMLGAVLAIVVPYL 300
Cdd:pfam00528 135 GLGLLLIEAILGYDYPEIQG-PVLAAALILLLLNLLVDILQRLL 177
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
11-300 4.63e-82

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 250.05  E-value: 4.63e-82
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  11 APVAPRRVSPLDRLQGWLPKLVLAPSVVVVLFCMYGYIGWTLLLSFTNSRFM-PSYKWAGLSQYQRLWDNDRWWVASKNL 89
Cdd:COG1175   2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLgPPPEFVGLDNYARLFTDPRFWNALGNT 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  90 LLFGGSFIAICLVLGVFLAVLLDQRIRREGFIRTLYLYPMALSMIVTGTAWKWLLNPGLG-LDKLLRDWGWEGFrfDWLV 168
Cdd:COG1175  82 LLFTVVSVPLQLVLGLLLALLLNRKLRGRGFFRTLFFLPWVISPVVVALIWKWLFNPDYGlLNALLGALGLEPI--NWLG 159
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 169 DPERVVYCLVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFDL 248
Cdd:COG1175 160 DPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQVFDL 239
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|..
gi 15598385 249 VAAMTAGGPGYSSDLPAMFMYAHTFTRGQMGLGAASAMLMLGAVLAIVVPYL 300
Cdd:COG1175 240 VYVLTGGGPGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLLQL 291
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
31-283 3.46e-20

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 88.61  E-value: 3.46e-20
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  31 LVLAPSVVVVLFC---MYGyigwtLLLSFTNsrFMPSY-----KWAGLSQYQRLWDNDRWWVASKNLLLFGGSFIAICLV 102
Cdd:COG4209  32 MLLPGLIYLLIFSylpMYG-----IVIAFKD--YNPFKgifgsPWVGLKNFKFLFSSPDFWRVLRNTLLISLLKLVFGFP 104
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 103 LGVFLAVLLDQrIRREGFIRT----LYLyPMALSMIVTGTAWKWLLNPGLGL-DKLLRDWGWEgfRFDWLVDPERVVYCL 177
Cdd:COG4209 105 LPIILALLLNE-LRSKRFKKTvqtiSYL-PHFLSWVVVAGIVYQFLSPDTGLvNQLLRALGGE--PINFLTEPKYFRPIY 180
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 178 VIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVfFSALMILA--HIAIKSFDLVAAMTAg 255
Cdd:COG4209 181 VFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHITLPGIRPT-IVILLILNigNILNVGFEQIYLLYN- 258
                       250       260
                ....*....|....*....|....*....
gi 15598385 256 GPGYS-SDLPAMFMYAHTFTRGQMGLGAA 283
Cdd:COG4209 259 PLNYStSDVIDTYVYRIGLQNGDYSYATA 287
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
61-303 2.04e-19

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 86.03  E-value: 2.04e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385   61 FMPSYKWAGLSQYQRLWDNDRWWVASKNLLLFGGSFIAICLVLGVFLAVLLDQRIRREGFIRTLYLYPMALSMIVTGTAW 140
Cdd:PRK10561  32 FGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFAALVDYVVRGSRFYQTLMLLPYAVAPAVAAVLW 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  141 KWLLNPGLGL-DKLLRDWgweGFRFDWLVDPERVVYCLVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIY 219
Cdd:PRK10561 112 IFLFNPGRGLiTHFLAEF---GYDWNHAQNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIRRF 188
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  220 LRIVLPSLRPVFFSALMI-LAHIAIKSFDLVAAMTAGGPGYSSDLPAMFMYAHTFTRGQMGLGAA-SAMLMLGAVLAIVV 297
Cdd:PRK10561 189 FKLALPLIAPVSFFLLVVnLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLSSSAAqSVVLMFLVIVLTVV 268

                 ....*.
gi 15598385  298 PYLYSE 303
Cdd:PRK10561 269 QFRYVE 274
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
27-309 2.51e-17

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 79.77  E-value: 2.51e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  27 WLPKLVLAPSVVVVLFCMYGYIGWTLLLSFTNSRFmPSYKWAGLS--QYQRLWDNDRWWVASKNLLLFGGSFIAICLVLG 104
Cdd:COG1177   3 RLGRLLLRLFLALVLLFLYLPILVLVLYSFNDSWF-LTFPPEGFTlrWYAELFSDPRLLDALLNSLLIALLSTLLATVLG 81
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 105 VFLAVLLDQ-RIRREGFIRTLYLYPMALSMIVTGTAwkwllnpglgldkLLRDWGWEGFRFDWLVdpervvycLVIAAVW 183
Cdd:COG1177  82 TPAALALARyRFRGRRLLLALLLLPLVVPGIVLGVA-------------LLLLFSALGLSGGLWG--------LILAHVV 140
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 184 QASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSAlMILAHIAikSFD-LVAAMTAGGPGYSSd 262
Cdd:COG1177 141 FTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAG-ALLAFTL--SFDeFVITLFLAGPGVTT- 216
                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*..
gi 15598385 263 LPaMFMYAHTFTRGQMGLGAASAMLMLGAVLAIVVPYLYSELRGKRH 309
Cdd:COG1177 217 LP-VYIYSMIRRGISPEINALSTLLILLSLLLLLLAERLRRRGERRR 262
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
25-308 1.65e-13

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 69.41  E-value: 1.65e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  25 QGWLPKLVLAPSVVVVLFCMYGYIGWTLLLSFTNSRFMPSYKWA-GLSQYQRLWDNDRWWVASKNLLLFGGSFIAICLVL 103
Cdd:COG1176   7 RRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPGfTLENYARLFTDPLYLKVLLRTLWIALLTTLICLLL 86
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 104 GVFLAVLLDQ-RIRREGFIRTLYLYPMALSMIVTGTAWKWLLNPGLGLDKLLRDWGWEGFRFDWLVDPERVVyclvIAAV 182
Cdd:COG1176  87 GYPIAYFLARaPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEPLRLLYTEFAVV----IGLV 162
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 183 WQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFdLVAAMTAGGpgySSD 262
Cdd:COG1176 163 YVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAF-VTPALLGGG---KVL 238
                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*.
gi 15598385 263 LPAMFMYAHTFTRGQMGLGAASAMLMLGAVLAIVVPYLYSELRGKR 308
Cdd:COG1176 239 MIGNLIYQQFLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRL 284
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
31-310 1.92e-13

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 70.58  E-value: 1.92e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  31 LVLAPSVVVVLFCMYGyIGWTLLLSFTNsrfmpsykwaGLSQYQRLWDNDRWWVASKNLLLFGGSFIAICLVLGVFLAVL 110
Cdd:COG1178  12 LLLLLALLLALLVLLP-LLALLLRAFTD----------GLANFWALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWL 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 111 LDQ-RIRREGFIRTLYLYPMALSMIVTGTAWKWLLNPGLGLDKLLRDWgwegfrFDWLVDPERVVYCLVIAAVWQASGFV 189
Cdd:COG1178  81 LARtDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLRAL------FGLEPPDIYGLGGIILVLVLFNYPYV 154
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 190 MALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFDLVAAMtaggpGYSSDLPAMFMY 269
Cdd:COG1178 155 YLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVL-----GGGYTTLTTAIY 229
                       250       260       270       280
                ....*....|....*....|....*....|....*....|.
gi 15598385 270 AHTFTRGQMGLGAASAMLMLGAVLAIVVPYLYSELRGKRHA 310
Cdd:COG1178 230 QAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRRRYAT 270
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
8-297 6.43e-10

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 59.79  E-value: 6.43e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385   8 YPTAPVAPRRVSPLdRLQGWLPKLVLAPSVVVVLFCM--YGYIGWTLLLSFTNSRFmpsykwaGLSQYQRLWDNDRWWVA 85
Cdd:COG1178 268 YATVGGRARRPRRV-KLGRWRWLALALCLLLVLLGLLlpLLALLLWSLTKALDDNL-------TLDNYRFVLLDPSLLRA 339
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  86 SKNLLLFGGSFIAICLVLGVFLAVLLD-QRIRREGFIRTLYLYPMALSMIVTGTAWKWLLNPGLGLdkLLRDWGWegfrf 164
Cdd:COG1178 340 LLNSLLLALLAALLAVLLALLLAYLVRrRRGRLARLLDRLAMLPYAVPGIVLGLGLLLLFNRPLPL--LLYGTLA----- 412
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 165 dwlvdpervvyCLVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIK 244
Cdd:COG1178 413 -----------ILVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMK 481
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|...
gi 15598385 245 sfDLVAAMTAGGPGYssDLPAMFMYAHTfTRGQMGLGAASAMLMLGAVLAIVV 297
Cdd:COG1178 482 --ELSATLLLRPPGF--ETLAVLIYQLA-SSGRYGEAAALALLLVLVSLLPVL 529
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
90-296 5.16e-07

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 49.20  E-value: 5.16e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  90 LLFGGSFIAICLVLGVFLAVLLDQRIRR-EGFIRTLYLYPMALSMIVTGTAWKWLLnpglgldkllrdwgweGFRFDWLV 168
Cdd:cd06261   5 LLLALIATLLALVLGLLLGIILARKRGKlDRLLRRIIDLLLSLPSLVLGLLLVLLF----------------GVLLGWGI 68
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 169 DPERVVYCLVIAAVWQAsGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFDL 248
Cdd:cd06261  69 LPGLGLPALILALLLIA-PFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFAL 147
                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 15598385 249 VAAMTAGGPGYSSDLPAMFmyahtFTRGQMGLGAASAMLMLGAVLAIV 296
Cdd:cd06261 148 VSFLGGGEAPGPGTGLLLI-----FAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
177-300 5.31e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 46.14  E-value: 5.31e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385   177 LVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSFDLVAAMTAGG 256
Cdd:pfam00528  55 AIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWP 134
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 15598385   257 PGYSSDLPAMFMYAHTFTRGqMGLGAASAMLMLGAVLAIVVPYL 300
Cdd:pfam00528 135 GLGLLLIEAILGYDYPEIQG-PVLAAALILLLLNLLVDILQRLL 177
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
92-229 3.03e-05

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 44.74  E-value: 3.03e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  92 FGGSFIA--ICLVLGVFLAVLL---DQRIRRegFIRTLYLYPMALSMIVTGTAWKWLLNPGLGLDKLLRDWGWEgFRFDW 166
Cdd:COG0555  60 LGTALIAalINLVFGLPLAWVLvryRFPGKR--LVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGIK-VAFTP 136
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15598385 167 LvdpervvyCLVIAAVWQASGFVMALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRP 229
Cdd:COG0555 137 L--------GIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLP 191
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
179-258 4.12e-04

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 41.29  E-value: 4.12e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 179 IAAVWQASGFVMAL-FLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMILAHIAIKSfdLVAA-MTAGG 256
Cdd:COG0600 129 IFVIFLGAFFPILLnTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAWIG--LVVAeLLGAS 206

                ..
gi 15598385 257 PG 258
Cdd:COG0600 207 SG 208
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
37-237 2.13e-03

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 38.92  E-value: 2.13e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385  37 VVVVLFCMYGYIgWTLLLSFTNSRFMPSYKWAG------LSQYQRLWDNDRWWVASKNLLLFGGSFIAICLVLGVFLAVL 110
Cdd:COG0395  22 ILLALLFLFPLY-WMVVTSFKPPAEIFSGPPSLlpseftLENYRAAFTDGPFGRYLLNSLIVAVVSTVLSLLLSSLAAYA 100
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15598385 111 LDQ-RIRREGFIRTLYLYPMALSMIVTGtawkwllnpgLGLDKLLRDWGWEGFRFDwlvdpervvycLVIAAVWQASGFV 189
Cdd:COG0395 101 LARfRFRGRKLLFLLILATLMIPGQVLL----------IPLYLLFRQLGLLNTYWG-----------LILPYLAFGLPFG 159
                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*...
gi 15598385 190 MALFLAGLRGVDPAIVRAAQVDGASLPTIYLRIVLPSLRPVFFSALMI 237
Cdd:COG0395 160 IFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPLSKPALATVAIF 207
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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