|
Name |
Accession |
Description |
Interval |
E-value |
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
8-620 |
0e+00 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 611.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 8 WKYLLILAVLAVGFIYSAPNLYPddpavqisgastalqvtqadvdraakaltdagiavkadslskkgglirlvkqddqlp 87
Cdd:PRK05812 1 WKYLLILLVLLIGLLYALPNLRG--------------------------------------------------------- 23
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 88 akevvrrtlgddyvvalNLAQTTPEWLRKLGGSPMKLGLDLSGGVHFLLEVDMDKAVDARLKVYESEVKSLLRKERVRYR 167
Cdd:PRK05812 24 -----------------ALAPATPEWLPALGAKPMKLGLDLRGGVHFLLEVDMDDALKKRLESLADDLRSLLREKKIRYG 86
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 168 SlpiqdraIQLGFTDSESLDKARSLIAKDFRdfevvpeernglqvlrvaLTQAKLAEIREYSIKQNLTTVRNRVNELGVS 247
Cdd:PRK05812 87 G-------VEITFRDAEDRDKAIALLRKLSS------------------LTEAELKEITEEALEQAIEIIRNRVNELGVA 141
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 248 EPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLEFRLaaepdalksatetfefreprrppVPlergVIITGDQVTDAS 327
Cdd:PRK05812 142 EPVIQRQGADRIVVELPGVQDTARAKEILGKTATLEFRL-----------------------VP----VILTGDDITDAS 194
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 328 ASFDENGRPQVNIRLDGHGGELMNRATRNNVGRSMAVVFieqkpvtrytkqmvDGvekevavpafkeekQIISLATIQSP 407
Cdd:PRK05812 195 ASFDQQGQPVVNITLDSEGAKKFADITKANIGKRMAIVL--------------DG--------------EVISAPVIQSA 246
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 408 L-GNQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRFFGVIAT 486
Cdd:PRK05812 247 ItGGSAQITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIAN 326
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 487 VALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLTSL 566
Cdd:PRK05812 327 IALVANLVLILAVLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTL 406
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 15599016 567 LVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFG-GRDFKKLWI 620
Cdd:PRK05812 407 IAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLLYGrRKRLKKLSI 461
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
86-620 |
3.52e-178 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 511.58 E-value: 3.52e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 86 LPAKEVVRRTLGDDYVVALNLaqttpeWLRKLGGSPMKLGLDLSGGVHFLLEVDMDKAVDARlkvyesevksllrkervr 165
Cdd:COG0342 1 MKAKFLLWRLLLLLLVVALSL------VAPNGPAKPIKLGLDLQGGVHLLLEVDTDAALDED------------------ 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 166 yrslpiqdraiqlgftdsesldkarsliakdfrdfevvpeernglqvlrvaltQAKLAEIREYSIKQNLTTVRNRVNELG 245
Cdd:COG0342 57 -----------------------------------------------------GDGIREVTEEALDQAIEILRNRVNELG 83
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 246 VSEPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLEFRL----AAEPDALKSATETFEFREPRrpPVPLERGVIITGD 321
Cdd:COG0342 84 VSEPVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLvddsADAQAAVPAGSELLPCRDGQ--PYLLLGPVVLTGD 161
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 322 QVTDASASFD-ENGRPQVNIRLDGHGGELMNRATRNNVGRSMAVVFIEQkpvtrytkqmvdgvekevavpafkeekqIIS 400
Cdd:COG0342 162 DLTDASAGFDqQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVLDGE----------------------------VIS 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 401 LATIQSPL-GNQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYR 479
Cdd:COG0342 214 APVIQEPItGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYR 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 480 FFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAIL 559
Cdd:COG0342 294 LPGLVANIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTIL 373
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15599016 560 DANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGGRDFKKLWI 620
Cdd:COG0342 374 DANVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKKLGI 434
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
124-606 |
1.17e-139 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 412.07 E-value: 1.17e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 124 LGLDLSGGVHFLLEVDMDKAVDARLkvyesevksllrkervryrslpiqdraiqlgftdsesldkarsliakdfrdfevv 203
Cdd:TIGR01129 1 LGLDLRGGARVLLEVDMSTAVVLKL------------------------------------------------------- 25
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 204 peernglqvlrvalTQAKLAEIREYSIKQNLTTVRNRVNELGVSEPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLE 283
Cdd:TIGR01129 26 --------------SEAEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAKDILGGTATLE 91
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 284 FRL-----AAEPDALK----SATETFEFREPRRPPVPLERGVIITGDQVTDASASFDE-NGRPQVNIRLDGHGGELMNRA 353
Cdd:TIGR01129 92 FRLvddesTSPDDALAgnvpAGSELLDSRSGDPKYYLLKKSPVLTGDHITDATSSVDQrSGQPVVSFSLDSEGARIFGDF 171
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 354 TRNNVGRSMAVVFIEQkpvtrytkqmvdgvekevavpafkeekqIISLATIQSPL-GNQFRITGLDGPGESSELALLLRA 432
Cdd:TIGR01129 172 TQANIGKRLAIVLDNK----------------------------VVSAPTIQEAItGGSGQITGNFTAEEANDLALVLRS 223
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 433 GGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRFFGVIATVALAFNMVMLVALMSILGATLTLPGI 512
Cdd:TIGR01129 224 GALPAPLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGI 303
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 513 AGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGII 592
Cdd:TIGR01129 304 AGLILTIGMAVDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGII 383
|
490
....*....|....
gi 15599016 593 TSMFTAIMVTRAMV 606
Cdd:TIGR01129 384 ASLFTALVFTRLLL 397
|
|
| SecD-TM1 |
pfam13721 |
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane ... |
2-104 |
5.64e-43 |
|
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane region of the SecD export protein. SecD is directly involved in protein secretion and important for the release of proteins that have been translocated across the cytoplasmic membrane.
Pssm-ID: 463968 [Multi-domain] Cd Length: 103 Bit Score: 149.59 E-value: 5.64e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 2 LNKYPLWKYLLILAVLAVGFIYSAPNLYPDDPAVQISGASTALQVTQADVDRAAKALTDAGIAVKADSLSKKGGLIRLVK 81
Cdd:pfam13721 1 MNRYPLWKYLLILVVLLIGLLYALPNLYGEDPAVQISAARGGAKVDEATLDRVEQALKAAGIPVKSIELEGDSLLVRFDS 80
|
90 100
....*....|....*....|...
gi 15599016 82 QDDQLPAKEVVRRTLGDDYVVAL 104
Cdd:pfam13721 81 TDDQLKAKDVLQRALGDDYVVAL 103
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
446-601 |
3.51e-16 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 76.88 E-value: 3.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 446 TIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYR-FFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVD 524
Cdd:pfam02355 20 TVGPTVGSELARKAVLALLFALLLILIYVGLRFEwRFALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLTIIGYSVN 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15599016 525 ANVLIFSRIREEL--ANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMV 601
Cdd:pfam02355 100 DTVVVFDRVRENLrkKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVGVIVGTYSSIFI 178
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
462-617 |
1.35e-12 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 70.96 E-value: 1.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 462 ASLWGMLFVSLFIIVI----YRFFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREEL 537
Cdd:NF037998 446 ASIIFLLILAIAIMIYllfaYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHL 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 538 ANGmsvQRAIHEGFNRA----FTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGGR 613
Cdd:NF037998 526 YKN---KRSIEESFKIAnketIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMIWLTIKLQ 602
|
....
gi 15599016 614 DFKK 617
Cdd:NF037998 603 WFKK 606
|
|
| PRK10629 |
PRK10629 |
EnvZ/OmpR regulon moderator MzrA; |
1-125 |
1.31e-07 |
|
EnvZ/OmpR regulon moderator MzrA;
Pssm-ID: 236728 Cd Length: 127 Bit Score: 50.77 E-value: 1.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 1 MLNKYP-----LWKYLLILAVLAVGFIYSApnLYPDDPAVQI----SGAST--ALQVTQAdvdraakaLTDAGIAVKA-- 67
Cdd:PRK10629 1 MINPRMslrqlAWLGAVLLLLAALLLAWSA--LRQQESTLAIravhQGASLpdGFYVYQH--------LDANGIHIKSit 70
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15599016 68 ---DSLskkggLIRLVKQDDQLPAKEVVRRTLGDDYVVAL-NLAQTTPEWLRKLGGSPMKLG 125
Cdd:PRK10629 71 penDSL-----LIRFDSPEQSAAAKEVLDRTLPHGYIIAQqDDNSQAMQWLTRLRDNSHRLG 127
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| secD |
PRK05812 |
preprotein translocase subunit SecD; Reviewed |
8-620 |
0e+00 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 235615 [Multi-domain] Cd Length: 462 Bit Score: 611.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 8 WKYLLILAVLAVGFIYSAPNLYPddpavqisgastalqvtqadvdraakaltdagiavkadslskkgglirlvkqddqlp 87
Cdd:PRK05812 1 WKYLLILLVLLIGLLYALPNLRG--------------------------------------------------------- 23
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 88 akevvrrtlgddyvvalNLAQTTPEWLRKLGGSPMKLGLDLSGGVHFLLEVDMDKAVDARLKVYESEVKSLLRKERVRYR 167
Cdd:PRK05812 24 -----------------ALAPATPEWLPALGAKPMKLGLDLRGGVHFLLEVDMDDALKKRLESLADDLRSLLREKKIRYG 86
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 168 SlpiqdraIQLGFTDSESLDKARSLIAKDFRdfevvpeernglqvlrvaLTQAKLAEIREYSIKQNLTTVRNRVNELGVS 247
Cdd:PRK05812 87 G-------VEITFRDAEDRDKAIALLRKLSS------------------LTEAELKEITEEALEQAIEIIRNRVNELGVA 141
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 248 EPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLEFRLaaepdalksatetfefreprrppVPlergVIITGDQVTDAS 327
Cdd:PRK05812 142 EPVIQRQGADRIVVELPGVQDTARAKEILGKTATLEFRL-----------------------VP----VILTGDDITDAS 194
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 328 ASFDENGRPQVNIRLDGHGGELMNRATRNNVGRSMAVVFieqkpvtrytkqmvDGvekevavpafkeekQIISLATIQSP 407
Cdd:PRK05812 195 ASFDQQGQPVVNITLDSEGAKKFADITKANIGKRMAIVL--------------DG--------------EVISAPVIQSA 246
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 408 L-GNQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRFFGVIAT 486
Cdd:PRK05812 247 ItGGSAQITGNFTAEEARDLALLLRAGALPAPLEIVEERTIGPSLGADSIRAGLIAGLIGLALVLLFMILYYRLFGLIAN 326
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 487 VALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLTSL 566
Cdd:PRK05812 327 IALVANLVLILAVLSLLGATLTLPGIAGIVLTIGMAVDANVLIFERIREELREGRSLRSAIEAGFKRAFSTILDSNITTL 406
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*
gi 15599016 567 LVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFG-GRDFKKLWI 620
Cdd:PRK05812 407 IAAIILYALGTGPVKGFAVTLGIGILTSMFTAITVTRALVNLLYGrRKRLKKLSI 461
|
|
| secD |
PRK12933 |
protein translocase subunit SecD; |
2-617 |
1.99e-180 |
|
protein translocase subunit SecD;
Pssm-ID: 183831 [Multi-domain] Cd Length: 604 Bit Score: 523.86 E-value: 1.99e-180
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 2 LNKYPLWKYLLILAVLAVGFIYSAPNLYPDDPAVQISGASTALQVTQAdvdrAAKALTDAGIAVKADSLSKKGGLIRLVK 81
Cdd:PRK12933 10 LNHYSAWKYVVLIVTIIILLLSAIPTWYGEDAAVQVSAKAGLLLNVVE----LRQLLQAQGINVKRIDQKEGKTLIVLDD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 82 QDDQLPAKEVVRRTLGDDYVVALNLAQTTPEWLRKLGGSPMKLGLDLSGGVHFLLEVDMDKAVDARLKVYESEVKSLLRK 161
Cdd:PRK12933 86 DSQQSQAKTLLSSMVKEPKELTLSLASAAPKWLQNMGFSPIKLGLDLRGGVQFLLDVDVDPVYQEQRDALVDSVRQFLRE 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 162 ERVRYRSLPIQD-RAIQLGFTDSESLDKARSLIAKDFRDFEVVPEERNGLQVlrvALTQAKLAEIREYSIKQNLTTVRNR 240
Cdd:PRK12933 166 QRIRGVSVRLDDsDQLAVTTPDNDARSAVRQFIQQNYPGWQVTNSDDRGLQL---KLSQQEKTKFRNLTVQQNLQIMRSR 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 241 VNELGVSEPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLEFRLAAEPDALKSATetfeFREPRRPPVPLERGVIITG 320
Cdd:PRK12933 243 IEELGITEALVQRQGEHRIRIELPGVQDPAAAKNVIGATASLAFYEVKESGSVNAKV----LKDKNGRPVYVARRPVLGG 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 321 DQVTDASASFDENGRPQVNIRLDGHGGELMNRATRNNVGRSMAVVFIEqkpvtrYTKQMVDGVEKEvavpafkeeKQIIS 400
Cdd:PRK12933 319 EHIVDARASLGEMGMAEVNISLDRAGGKKMSDFSRDNIGKPMATSYSE------YSRDEQGKTKQS---------EEVIS 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 401 LATIQSPLGNQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRF 480
Cdd:PRK12933 384 VATIQSQLGDRFRITGAGSYQEAQQLALLLRAGSLTAPVTIVEERTIGPSLGAENIENGFAALALGMGITLLFMALWYRR 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 481 FGVIATVALAFNMVMLVALMSIL-GATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAIL 559
Cdd:PRK12933 464 LGWVANVALIANMVCLFGLLALIpGAVLTLPGIAGLVLTVGMAVDTNVLIFERIKDKLKEGRSFAQAIDTGFDSAFSTIF 543
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*...
gi 15599016 560 DANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFgGRDFKK 617
Cdd:PRK12933 544 DANFTTMITAVVLYSIGNGPIQGFALTLGLGLLTSMFTGIFASRALINLVY-GRDARR 600
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
86-620 |
3.52e-178 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 511.58 E-value: 3.52e-178
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 86 LPAKEVVRRTLGDDYVVALNLaqttpeWLRKLGGSPMKLGLDLSGGVHFLLEVDMDKAVDARlkvyesevksllrkervr 165
Cdd:COG0342 1 MKAKFLLWRLLLLLLVVALSL------VAPNGPAKPIKLGLDLQGGVHLLLEVDTDAALDED------------------ 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 166 yrslpiqdraiqlgftdsesldkarsliakdfrdfevvpeernglqvlrvaltQAKLAEIREYSIKQNLTTVRNRVNELG 245
Cdd:COG0342 57 -----------------------------------------------------GDGIREVTEEALDQAIEILRNRVNELG 83
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 246 VSEPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLEFRL----AAEPDALKSATETFEFREPRrpPVPLERGVIITGD 321
Cdd:COG0342 84 VSEPVIQRQGDDRIVVELPGVQDPAEAKELLGKTAKLEFRLvddsADAQAAVPAGSELLPCRDGQ--PYLLLGPVVLTGD 161
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 322 QVTDASASFD-ENGRPQVNIRLDGHGGELMNRATRNNVGRSMAVVFIEQkpvtrytkqmvdgvekevavpafkeekqIIS 400
Cdd:COG0342 162 DLTDASAGFDqQTGQPVVSFTLDSEGAKKFADATRENVGKPLAIVLDGE----------------------------VIS 213
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 401 LATIQSPL-GNQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYR 479
Cdd:COG0342 214 APVIQEPItGGSAQITGSFTVEEAQDLALLLRAGALPAPLEIVEERTVGPTLGADSIEKGLIAGLIGLLLVALFMLLYYR 293
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 480 FFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAIL 559
Cdd:COG0342 294 LPGLVANIALALNVVLLLGVLSLLGATLTLPGIAGIILTIGMAVDANVLIFERIREELRAGRSLRAAIEAGFKRAFSTIL 373
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15599016 560 DANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGGRDFKKLWI 620
Cdd:COG0342 374 DANVTTLIAAVVLFVLGTGPVKGFAVTLILGILISMFTAVPVTRPLLNLLLGRRRLKKLGI 434
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
124-606 |
1.17e-139 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 412.07 E-value: 1.17e-139
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 124 LGLDLSGGVHFLLEVDMDKAVDARLkvyesevksllrkervryrslpiqdraiqlgftdsesldkarsliakdfrdfevv 203
Cdd:TIGR01129 1 LGLDLRGGARVLLEVDMSTAVVLKL------------------------------------------------------- 25
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 204 peernglqvlrvalTQAKLAEIREYSIKQNLTTVRNRVNELGVSEPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLE 283
Cdd:TIGR01129 26 --------------SEAEVNAIRKDALEQVITILRNRVNALGVSEPVVQRQGKDRIVVELPGVTDTSRAKDILGGTATLE 91
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 284 FRL-----AAEPDALK----SATETFEFREPRRPPVPLERGVIITGDQVTDASASFDE-NGRPQVNIRLDGHGGELMNRA 353
Cdd:TIGR01129 92 FRLvddesTSPDDALAgnvpAGSELLDSRSGDPKYYLLKKSPVLTGDHITDATSSVDQrSGQPVVSFSLDSEGARIFGDF 171
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 354 TRNNVGRSMAVVFIEQkpvtrytkqmvdgvekevavpafkeekqIISLATIQSPL-GNQFRITGLDGPGESSELALLLRA 432
Cdd:TIGR01129 172 TQANIGKRLAIVLDNK----------------------------VVSAPTIQEAItGGSGQITGNFTAEEANDLALVLRS 223
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 433 GGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRFFGVIATVALAFNMVMLVALMSILGATLTLPGI 512
Cdd:TIGR01129 224 GALPAPLQILEERTIGPSLGADSIEAGIKAGLIGLVLVLVFMILYYRLFGLIAAIALVINIVLILAILSAFGATLTLPGI 303
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 513 AGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGII 592
Cdd:TIGR01129 304 AGLILTIGMAVDANVLIYERIKEELRLGKSVRQAIEAGFERAFSTIFDANITTLIAALILYVFGTGPVKGFAVTLAIGII 383
|
490
....*....|....
gi 15599016 593 TSMFTAIMVTRAMV 606
Cdd:TIGR01129 384 ASLFTALVFTRLLL 397
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
229-620 |
1.75e-118 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 369.56 E-value: 1.75e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 229 SIKQNLTTVRNRVNELGVSEPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLEFRLAAEPDALKSATETFEFREPRRP 308
Cdd:PRK13024 60 ALDSTVEVLRNRIDGLGVSEPNIQREGNNRIRVELPGVQDPERARELLGSTAKLTFRDVTDPPPPGVGGPVVGPDEGKDT 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 309 PVplERGVIITGDQVTDASASFD--ENGRPQVNIRLDGHGGELMNRATRNNV-----GRSMAVVFieqkpvtrytkqmvd 381
Cdd:PRK13024 140 AV--LNPVLLSGDDLTDAGAKFDqdQTNRPSVSLKLKSEGAKKWAKVTEKNSkkgppNNRIAIVL--------------- 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 382 gvekevavpafkeEKQIISLATIQSPL-GNQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGI 460
Cdd:PRK13024 203 -------------DPKVISAPTVNQPInGGSVQISGNFTVEEAKDLANLLNAGALPAPLKIIESRSVGPTLGQDAIDAGI 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 461 DASLWGMLFVSLFIIVIYRFFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANG 540
Cdd:PRK13024 270 IAGIIGFALIFLFMLVYYGLPGLIANIALLLYIFLTLGALSSLGAVLTLPGIAGLVLGIGMAVDANVLIFERIKEELRKG 349
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 541 MSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGGRDFKKLWI 620
Cdd:PRK13024 350 KSLKKAFKKGFKNAFSTILDSNITTLIAAAILFFFGTGPVKGFATTLIIGILASLFTAVFLTRLLLELLVKRGDKKPFLF 429
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
111-606 |
2.35e-115 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 364.04 E-value: 2.35e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 111 PEWLRKlggSPMKLGLDLSGGVHFLLEVDMDKAVDARLKVYESEVKSLLRKERVRYRSLPIQDRAIQLGFTDSESLDKAR 190
Cdd:PRK14726 37 PSWLPH---RQVTLGLDLQGGSHIVLKVERSDIVKDRLEETVANIRNALRDAGIRYTGLTGNGQTVQVRITDPAQTQAAV 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 191 SL-------IAKDFRDFEVVPE---ERNGLQVLRVALTQAKLAEIREYSIKQNLTTVRNRVNELGVSEPLVQRQGANRIV 260
Cdd:PRK14726 114 DAlkpltapVSAGGLGGSSIQEltlQEGGEGQLRLQLTDAGIDYRVSSALTQSIEVVRRRVAELGTTEPLIRRQGDDRIV 193
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 261 VELPGVQDTAEAKRILGKTANLEFRLAaepDALKSATETFEFREPR---------RPPVP--LERGVIITGDQVTDASAS 329
Cdd:PRK14726 194 VQVPGLVDPQRLKNLLNQPAKLSFRLV---DSSMPAQEALNGRPPAtsevlysldDPPVPylVERRAFVSGENLVDAQPV 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 330 FD-ENGRPQVNIRLDGHGGELMNRATRNNVGRSMAVVFieqkpvtrytkqmvDGvekevavpafkeekQIISLATIQSP- 407
Cdd:PRK14726 271 FDpQTNEPVVTFRLDAEGTQRFAQATQQNVGKHFAIVL--------------DG--------------QVISAPVIDEAi 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 408 LGNQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRFFGVIATV 487
Cdd:PRK14726 323 TGGEGRISGNFSEQGANDLAVLLRAGALPATLTVVEERTVGPGLGADSIAAGLVAGLIAAILVAALMIGFYGFLGVIAVI 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 488 ALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLTSLL 567
Cdd:PRK14726 403 ALIVNVVLIIAVLSLLGATLTLPGIAGIVLTIGMAVDSNVLIYERIREEEKTGHSLIQALDRGFSRALATIVDANVTILI 482
|
490 500 510
....*....|....*....|....*....|....*....
gi 15599016 568 VGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMV 606
Cdd:PRK14726 483 AAVILFFLGSGAVRGFAVTLAVGILTTVFTAFTLTRSLV 521
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
445-599 |
1.94e-52 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 178.22 E-value: 1.94e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 445 RTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRFFGVIATV-ALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAV 523
Cdd:TIGR00916 35 GTVGPTLGGELIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIaALVHDVILILGVLSLFGATLTLPGIAGLLTIIGYSV 114
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15599016 524 DANVLIFSRIREEL--ANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAI 599
Cdd:TIGR00916 115 DDTVVIFDRIREELrkYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGGGAIKGFALTLGIGVIAGTYSSI 192
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
237-606 |
3.15e-52 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 191.75 E-value: 3.15e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 237 VRNRVNELGVSEPLVQRQGANRIVVELPGVQDTAEAKRILGKTANLEFR-----------LAAEPDALKSATETFEfrep 305
Cdd:PRK13023 76 MRQRLEELGYGNPVVEGEGRNQIRVEVPGLYDAQLLKDILTIRGNLSFRamddtmspddaIRGTPPADSEIVYSFD---- 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 306 rRPPVP--LERGVIITGDQVTDASASF-DENGRPQVNIRLDGHGGELMNRATRNNVGRSMAVVFieqkpvtrytkqmvdg 382
Cdd:PRK13023 152 -DPPVGylLKKTPILTGHDITDAKASIsADDGQPVITLTLDDNGRRRLADLTAQGNENSFAIVV---------------- 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 383 vekevavpafkeEKQIISLATIQSPLG-NQFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGID 461
Cdd:PRK13023 215 ------------DNQVVSAPTVSGPLDtSELQIEGAFDLQAANNMAVVLRSGALPQAVTVLEERTIASALGEDYASAAVL 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 462 ASLWGMLFVSLFIIVIYRFFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGM 541
Cdd:PRK13023 283 AALLAALVVGLFMVLSYGILGVIALVALVVNIIILTAVLSLIGASISLASIAGLVLTIGLAVDAHILIYERVREDRRKGY 362
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15599016 542 SVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMV 606
Cdd:PRK13023 363 SVVQAMESGFYRALSTIVDANLTTLIAALVLFLLGSGTVHGFALTVAIGIGTTLFTTLTFTRLLI 427
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
444-603 |
1.07e-43 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 168.50 E-value: 1.07e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 444 ERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRFFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAV 523
Cdd:PRK12911 896 EEVISPELGKSQRTQGIISVCLGLAVLIVLMSVYYRFGGVIASGAVLLNLLLIWAALQYLDAPLTLSGLAGIVLAMGMAV 975
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 524 DANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTR 603
Cdd:PRK12911 976 DANVLVFERIREEYLLSRSLSESVEAGYKKAFSAIFDSNLTTILASALLLMLDTGPIKGFALTLIIGIFSSMFTALFMTK 1055
|
|
| SecD-TM1 |
pfam13721 |
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane ... |
2-104 |
5.64e-43 |
|
SecD export protein N-terminal TM region; This domain appears to be the fist transmembrane region of the SecD export protein. SecD is directly involved in protein secretion and important for the release of proteins that have been translocated across the cytoplasmic membrane.
Pssm-ID: 463968 [Multi-domain] Cd Length: 103 Bit Score: 149.59 E-value: 5.64e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 2 LNKYPLWKYLLILAVLAVGFIYSAPNLYPDDPAVQISGASTALQVTQADVDRAAKALTDAGIAVKADSLSKKGGLIRLVK 81
Cdd:pfam13721 1 MNRYPLWKYLLILVVLLIGLLYALPNLYGEDPAVQISAARGGAKVDEATLDRVEQALKAAGIPVKSIELEGDSLLVRFDS 80
|
90 100
....*....|....*....|...
gi 15599016 82 QDDQLPAKEVVRRTLGDDYVVAL 104
Cdd:pfam13721 81 TDDQLKAKDVLQRALGDDYVVAL 103
|
|
| SecD_SecF |
pfam02355 |
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF ... |
446-601 |
3.51e-16 |
|
Protein export membrane protein; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force.
Pssm-ID: 280510 [Multi-domain] Cd Length: 189 Bit Score: 76.88 E-value: 3.51e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 446 TIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYR-FFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVD 524
Cdd:pfam02355 20 TVGPTVGSELARKAVLALLFALLLILIYVGLRFEwRFALGAIIALAHDVIITVGVFSLFGIEVDLATVAALLTIIGYSVN 99
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15599016 525 ANVLIFSRIREEL--ANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMV 601
Cdd:pfam02355 100 DTVVVFDRVRENLrkKTRATLNEIMNLSINQTLTRTINTSLTTLLVVVALFVFGGGSLKDFSLALLVGVIVGTYSSIFI 178
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
464-609 |
1.18e-15 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 80.67 E-value: 1.18e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 464 LWGMLFVSLFIIVIYR--FFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGM 541
Cdd:COG1033 612 LLALLLIFLLLLLAFRslRLGLISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREERRKGG 691
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15599016 542 SVQRAIHEGFNRAFTAILdanLTSL-LVGG--ILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLI 609
Cdd:COG1033 692 DLEEAIRRALRTTGKAIL---FTSLtLAAGfgVLLFSSFPPLADFGLLLALGLLVALLAALLLLPALLLLL 759
|
|
| SecF |
COG0341 |
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular ... |
446-598 |
7.09e-15 |
|
Preprotein translocase subunit SecF [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440110 [Multi-domain] Cd Length: 291 Bit Score: 75.47 E-value: 7.09e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 446 TIGPSLGADNIAKGIDAslwgmLFVSLFIIVIY---RF---FGVIATVALAFNMVMLVALMSILGATLTLPGIAGIvLT- 518
Cdd:COG0341 122 FVGPTVGKELTRKALLA-----LLVALIGILIYiafRFewrFAVGAVVALLHDVLITLGIFSLFGLEFDLTFIAAL-LTi 195
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 519 MGMAVDANVLIFSRIREELAN--GMS----VQRAIHEGFNRAF-TAildanLTSLLVGGILYAMGTGPVKGFAVTMSLGI 591
Cdd:COG0341 196 IGYSLNDTVVVFDRIRENLRKyrKMTlaeiINLSINQTLSRTInTS-----LTTLLVVLALLFFGGETLRDFALALLIGI 270
|
170
....*....|.
gi 15599016 592 IT----SMFTA 598
Cdd:COG0341 271 IVgtysSIFIA 281
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
464-601 |
2.34e-14 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 76.44 E-value: 2.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 464 LWGMLFVSLFIIVIYR-FFGVIAT-VALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGM 541
Cdd:COG1033 225 PLALLLILLLLFLFFRsLRGVLLPlLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERRKGL 304
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 542 SVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMV 601
Cdd:COG1033 305 DKREALREALRKLGPPVLLTSLTTAIGFLSLLFSDIPPIRDFGIVAAIGVLLAFLTSLTL 364
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
359-617 |
1.55e-13 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 73.73 E-value: 1.55e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 359 GRSMAVVFieQKPVTrytkqmVDGVEKEVAVPAFKEEKQIISLATIQSPLgnqFRITGLDGPGESSELALLLRAGGLAAP 438
Cdd:PRK13024 487 GTRYEIRT--DQPVD------LEQVRADLKELGLGEVNIVTFGSDNNQVL---VRTYGILSDDEEADTEIVAKLKNALKN 555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 439 MYFAEER---TIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYRF-FGVIATVALAFNMVMLVALMSILGATLTLPGIAG 514
Cdd:PRK13024 556 DKGGTIPsseTVGPTVGKELARNAIIAVLIALIGILLYILIRFEWtFSLGAILALLHDVLIVIGFFSLFRLEVDLTFIAA 635
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 515 IVLTMGMAVDANVLIFSRIREELAN--GMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGII 592
Cdd:PRK13024 636 ILTIIGYSINDTVVVFDRIRENLRLykKKDLREIVNKSINQTLSRTINTSLTTLLVLLALLIFGGSSLRNFSLALLVGLI 715
|
250 260
....*....|....*....|....*
gi 15599016 593 TSMFTAIMVTRAMVnLIFGGRDFKK 617
Cdd:PRK13024 716 VGTYSSIFIAAPLW-LDLEKRRLKK 739
|
|
| RND_1 |
NF037998 |
protein translocase SecDF, variant type; Members of this family are identified by TCDB as ... |
462-617 |
1.35e-12 |
|
protein translocase SecDF, variant type; Members of this family are identified by TCDB as belonging to 2.A.6.4.4, a variant 12-TM type SecDF, as found in Spiroplasma, Mesoplasma, and Acholeplasma.
Pssm-ID: 468306 Cd Length: 1237 Bit Score: 70.96 E-value: 1.35e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 462 ASLWGMLFVSLFIIVI----YRFFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREEL 537
Cdd:NF037998 446 ASIIFLLILAIAIMIYllfaYRLLGLFAIIIALTSISLTLYSPTWFGLAIGPESITAIFIAIGLVLESCSLLFEAFKKHL 525
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 538 ANGmsvQRAIHEGFNRA----FTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGGR 613
Cdd:NF037998 526 YKN---KRSIEESFKIAnketIGIIVDALVVLLIPNLSLFWIGSNSIKSFATILLVGVIISLVLVIIVARLMIWLTIKLQ 602
|
....
gi 15599016 614 DFKK 617
Cdd:NF037998 603 WFKK 606
|
|
| 3a0501s07 |
TIGR00966 |
protein-export membrane protein SecF; This bacterial protein is always found with the ... |
446-601 |
2.43e-12 |
|
protein-export membrane protein SecF; This bacterial protein is always found with the homologous protein-export membrane protein SecD. In numerous lineages, this protein occurs as a SecDF fusion protein. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273368 [Multi-domain] Cd Length: 246 Bit Score: 67.30 E-value: 2.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 446 TIGPSLGADNIAKGIDASLWGMLFVSLFIIVIY-RFFGVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVD 524
Cdd:TIGR00966 87 AVGPSVGGELARKAVLALLAALVLILIYITVRFeWRFALGAIVALVHDVIITVGVYSLFGIEVNLTTVAALLTIIGYSIN 166
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15599016 525 ANVLIFSRIREEL--ANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMV 601
Cdd:TIGR00966 167 DTVVVFDRIRENLrkYTRKTFTEVINLSINQTLSRTINTSLTTLLAVLALYVFGGGVIKDFSLALLVGVIVGTYSSIFI 245
|
|
| secF |
PRK13021 |
preprotein translocase subunit SecF; Reviewed |
447-601 |
3.67e-12 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 237274 [Multi-domain] Cd Length: 297 Bit Score: 67.57 E-value: 3.67e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 447 IGPSLGADNIAKGIDASLWGMLFVSLFIIviYRFFGVIAT---VALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAV 523
Cdd:PRK13021 116 VGPQVGQELAEQGGLALLVAMLCILGYLS--YRFEWRLASgalFALVHDVIFVLAFFALTQMEFNLTVLAAVLAILGYSL 193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 524 DANVLIFSRIREEL--ANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMV 601
Cdd:PRK13021 194 NDSIIIADRIRELLiaKPKLAIQEINNQAIVATFSRTMVTSGTTLMTVGALWIMGGGPLEGFSIAMFIGILTGTFSSISV 273
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
446-620 |
1.21e-10 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 64.47 E-value: 1.21e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 446 TIGPSLGADnIAKGIDASLWGMLFVS--LFIIVIYRFF-----GVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLT 518
Cdd:TIGR00921 178 TGSPAINYD-IEREFGKDMGTTMAISgiLVVLVLLLDFkrwwrPLLPLVIILFGVAWVLGIMGWLGIPLYATTLLAVPML 256
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 519 MGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTA 598
Cdd:TIGR00921 257 IGVGIDYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALALSEFPMVSEFGLGLVAGLITAYLLT 336
|
170 180
....*....|....*....|..
gi 15599016 599 IMVTRAMVNLIFGGRDFKKLWI 620
Cdd:TIGR00921 337 LLVLPALLQSIDIGREKVKKEI 358
|
|
| secD |
PRK08343 |
preprotein translocase subunit SecD; Reviewed |
239-603 |
3.45e-10 |
|
preprotein translocase subunit SecD; Reviewed
Pssm-ID: 236245 [Multi-domain] Cd Length: 417 Bit Score: 62.20 E-value: 3.45e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 239 NRVNELGVSEPLVQRQGANRIVVELPGVqDTAEAKRILGKTANLEFRLAAEPDalksATETFefreprrppvplergviI 318
Cdd:PRK08343 74 SRLNALGLKDIKVYPVGDQYIVVEVPGV-DADTAKEIIEKQGVFEARIQTPGN----NNETV-----------------L 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 319 TGDQVTD-ASASFDENGR-PQVNIRLDGHGGELMNRATRNnvgrSMAVVFIEQKPVTRYtkqmVDGveKEVAVPAFKEEk 396
Cdd:PRK08343 132 TGDDIESvGSPSQDPSGGaWGVPFTLSEDGAEKFAEVAKG----KGATDDPSGHPLDMY----LDG--ELIYAAPLSPD- 200
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 397 qiisLAT--IQSPLGN--QFRITGLDGPGESSELALLLRAGGLAAPMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSL 472
Cdd:PRK08343 201 ----LASglASGPVVItvGSTGTTEEAKEEAKELYIHLRSGALPVKLDIEGSGSVSPSLGEQFKKGSLIAGLLALLAVAL 276
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 473 FIIVIYRFFGVIATVAL--AFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSrirEELANGMSVQRAIHEG 550
Cdd:PRK08343 277 VVFLRYREPRIALPMVItsLSEVIIILGFAALIGWQLDLASIAGIIAVIGTGVDDLIIITD---EVLHEGKVPSRKVFLS 353
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 15599016 551 -FNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIItsmfTAIMVTR 603
Cdd:PRK08343 354 rIKRAFFIIFAAAATTIAAMSPLAVMGLGDLKGFAITTILGVL----IGVLITR 403
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
448-613 |
1.92e-08 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 57.47 E-value: 1.92e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 448 GPSLGADNIAKGIDASLWGMLFVSLFII-----VIYRffgviaTVALAFnMVMLVALMSILGAT---------LTLPGIA 513
Cdd:COG2409 155 GPAALAADLNEAFEEDLGRAELITLPVAlvvllLVFR------SLVAAL-LPLLTAGLAVGVALgllallaafTDVSSFA 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 514 GIVLTM---GMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLT---SLLVggiLYAMGTGPVKGFAVTM 587
Cdd:COG2409 228 PNLLTMlglGVGIDYALFLVSRYREELRAGEDREEAVARAVATAGRAVLFSGLTvaiALLG---LLLAGLPFLRSMGPAA 304
|
170 180
....*....|....*....|....*.
gi 15599016 588 SLGIITSMFTAIMVTRAMVnLIFGGR 613
Cdd:COG2409 305 AIGVAVAVLAALTLLPALL-ALLGRR 329
|
|
| PRK08578 |
PRK08578 |
preprotein translocase subunit SecF; Reviewed |
438-610 |
2.14e-08 |
|
preprotein translocase subunit SecF; Reviewed
Pssm-ID: 236302 [Multi-domain] Cd Length: 292 Bit Score: 56.09 E-value: 2.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 438 PMYFAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIVIYR-FFGVIATVALAF-NMVMLVALMSILGATLTLPGIAGI 515
Cdd:PRK08578 115 SELNYSEKQIGPTFGSQFQEQALKAVGFAFIGMAVVVFLIFRtPVPSLAVILSAFsDIIIALALMNLFGIELSLATVAAL 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 516 VLTMGMAVDANVLIFSRIreeLANGMSVQRAIHEgfnraftaildanltsllvggilyAMGTGpvkgfaVTMSLGIITSM 595
Cdd:PRK08578 195 LMLIGYSVDSDILLTTRV---LKRRGTFDESIKR------------------------AMRTG------ITMTLTTIAAM 241
|
170
....*....|....*.
gi 15599016 596 FT-AIMVTRAMVNLIF 610
Cdd:PRK08578 242 AVlYIVSTIPQAEVLA 257
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
463-604 |
7.91e-08 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 55.63 E-value: 7.91e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 463 SLWGMLFVslFIIVIYRFFG------VIATVALAfnMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANvlIFsriree 536
Cdd:COG4258 645 LLLALLLI--LLLLLLRLRSlrralrVLLPPLLA--VLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYA--LF------ 712
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15599016 537 langMSVQRAIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRA 604
Cdd:COG4258 713 ----FTEGLLDKGELARTLLSILLAALTTLLGFGLLAFSSTPALRSFGLTVLLGILLALLLAPLLAPR 776
|
|
| PRK10629 |
PRK10629 |
EnvZ/OmpR regulon moderator MzrA; |
1-125 |
1.31e-07 |
|
EnvZ/OmpR regulon moderator MzrA;
Pssm-ID: 236728 Cd Length: 127 Bit Score: 50.77 E-value: 1.31e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 1 MLNKYP-----LWKYLLILAVLAVGFIYSApnLYPDDPAVQI----SGAST--ALQVTQAdvdraakaLTDAGIAVKA-- 67
Cdd:PRK10629 1 MINPRMslrqlAWLGAVLLLLAALLLAWSA--LRQQESTLAIravhQGASLpdGFYVYQH--------LDANGIHIKSit 70
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15599016 68 ---DSLskkggLIRLVKQDDQLPAKEVVRRTLGDDYVVAL-NLAQTTPEWLRKLGGSPMKLG 125
Cdd:PRK10629 71 penDSL-----LIRFDSPEQSAAAKEVLDRTLPHGYIIAQqDDNSQAMQWLTRLRDNSHRLG 127
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
448-601 |
1.75e-07 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 53.45 E-value: 1.75e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 448 GPSLGADNIAKGIDASLWGMLFVSL---FII--VIYRFFG----VIATVAL----AFNMVMLVALMSILGATLTLPGIAG 514
Cdd:pfam03176 128 GPAATVADLRDAGDRDLGLIEAVTLvviFIIllIVYRSVVaallPLLTVGLslgaAQGLVAILAHILGIGLSTFALNLLV 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 515 IVLtMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILDANLT------SLLVGGILYAMGTGPVKGFAVTMS 588
Cdd:pfam03176 208 VLL-IAVGTDYALFLVSRYREELRAGEDREEAVIRAVRGTGKVVTAAGLTvaiamlALSFARLPVFAQVGPTIAIGVLVD 286
|
170
....*....|...
gi 15599016 589 LGIITSMFTAIMV 601
Cdd:pfam03176 287 VLAALTLLPALLA 299
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
481-608 |
2.38e-07 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 54.07 E-value: 2.38e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 481 FGVIATVALAFN-----MVMLVALMSILGATLTLPGIAGI----------VLTMGMAVDANVLIFSRIREELaNGMSVQR 545
Cdd:TIGR00921 578 ILVLMILLAVFRnpikaVFPLIAIGSGILWAIGLMGLRGIpsflamattiSIILGLGMDYSIHLAERYFEER-KEHGPKE 656
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15599016 546 AIHEGFNRAFTAILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNL 608
Cdd:TIGR00921 657 AITHTMERTGPGILFSGLTTAGGFLSLLLSHFPIMRNFGLVQGIGVLSSLTAALVVFPALLVL 719
|
|
| PRK13023 |
PRK13023 |
protein translocase subunit SecDF; |
414-606 |
3.72e-06 |
|
protein translocase subunit SecDF;
Pssm-ID: 171842 [Multi-domain] Cd Length: 758 Bit Score: 50.00 E-value: 3.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 414 ITGLDGPGESSELALLLRAGGLAAPMY-FAEERTIGPSLGADNIAKGIDASLWGMlfVSLFIIVIYRF---FGVIATVAL 489
Cdd:PRK13023 534 IIGSQEVGDDAEQTVAVKLRGEFEQDYsFQRVDVVGPTVSEQLSRAGVLAVILSL--IGIFIYVWFRFrwqLALGAVLST 611
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 490 AFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGMS--VQRAIHEGFNRAFTAILDANLTSLL 567
Cdd:PRK13023 612 LHDVVILSGMFIVFRMEFNLWSVAAILTIIGYSLNDTVVIYDRVRENLRRYKSapLPAIIDASINQTLSRTLLTSFVTFL 691
|
170 180 190
....*....|....*....|....*....|....*....
gi 15599016 568 VGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMV 606
Cdd:PRK13023 692 AHVPLYAFGGSEIRMFALALSVGIIVASYSSIFIAAPLL 730
|
|
| PRK14726 |
PRK14726 |
protein translocase subunit SecDF; |
406-601 |
3.60e-05 |
|
protein translocase subunit SecDF;
Pssm-ID: 237805 [Multi-domain] Cd Length: 855 Bit Score: 47.02 E-value: 3.60e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 406 SPLGNQFRITGLDGpGESSELALLLRAGGLAAPMY-FAEERTIGPSLGADNIAKGIDASLWGMLFVSLFIIViyRF---F 481
Cdd:PRK14726 621 SPRDALIRIASQDG-GENAEQSAVTLVRGELEDDYdFRRVEVVGPAVSGELTMAATLGVLAALAAILIYIWI--RFewqF 697
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 482 GVIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELA--NGMSVQRAIHEGFNRAFTAIL 559
Cdd:PRK14726 698 AVGAIIATLHDVILTLGLFVLTGIEFNLTSIAAILTIVGYSLNDTVVVYDRVRENLRryKKMPLPILIDASINQTLSRTV 777
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 15599016 560 DANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMV 601
Cdd:PRK14726 778 LTSATTLLALLALYLFGGEVIRSFTFAMLFGVAVGTFSSIYI 819
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
464-605 |
5.21e-05 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 46.64 E-value: 5.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 464 LWGMLFVslfIIVIYRFFG-----VIATVALAFNMVMLVALMSILGATL---TLpgiAGIVLTMGMAVDA------NVli 529
Cdd:COG0841 338 LEAILLV---VLVVFLFLRswratLIPAVAIPVSLIGTFAVMYLLGFSLnilTL---FALVLAIGIVVDDaivvveNI-- 409
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 530 fSRIREElanGMSVQRAIHEGFNRAFTAILDANLTS-------LLVGGI---LYamgtgpvKGFAVTMSLGIITSMFTAI 599
Cdd:COG0841 410 -ERHMEE---GLSPLEAAIKGAREVAGAVIASTLTLvavflplAFMGGItgqLF-------RQFALTVAIALLISLFVAL 478
|
....*.
gi 15599016 600 MVTRAM 605
Cdd:COG0841 479 TLTPAL 484
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
466-602 |
5.57e-05 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 46.25 E-value: 5.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 466 GMLFVSLFIIVIYRFFG----VIATVALAFNMVMLvALMsILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELANGM 541
Cdd:COG0841 860 ALLLVYLVLAAQFESFIqpliILLTVPLALIGALL-GLL-LTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLREEGM 937
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15599016 542 SVQRAIHEGFNRAFTAILdanLTSL--LVGGILYAMGTGP----VKGFAVTMSLGIITSMFTAIMVT 602
Cdd:COG0841 938 SLREAILEAARLRLRPIL---MTSLatILGLLPLALGTGAgaefRQPLGIAVIGGLLFSTLLTLFVV 1001
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
462-602 |
1.90e-04 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 44.60 E-value: 1.90e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 462 ASLWGMLFVSLFIIVIYRFFGVIATV--ALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELAN 539
Cdd:TIGR03480 274 AGLLSFVLVLVLLWLALRSPRLVFAVlvTLIVGLILTAAFATLAVGHLNLISVAFAVLFIGLGVDFAIQFSLRYREERFR 353
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15599016 540 GMSVQRAIHEGFNRAFTAILDANLTSLLvgGILYAMGTgpvkGFAVTMSLGII--TSMFTAIMVT 602
Cdd:TIGR03480 354 GGNHREALSVAARRMGAALLLAALATAA--GFFAFLPT----DYKGVSELGIIagTGMFIALFVT 412
|
|
| PRK12911 |
PRK12911 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
468-592 |
5.47e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 171815 [Multi-domain] Cd Length: 1403 Bit Score: 43.31 E-value: 5.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 468 LFVSLFIIVIY---RFFGVIATVALAFNMVMLVALMSILGAT--------LTLPGIAGIVLTMGMAVDANVLIFSRIREE 536
Cdd:PRK12911 1240 LFGALGIILLYvslRFEWRYAFSAICALIHDLLATCAVLVALhfflqkiqIDLQAIGALMTVLGYSLNNTLIIFDRIRED 1319
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15599016 537 ----LANGMSV--QRAIHEGFNRafTAILDANLTSLLVggILYAMGTGPVKGFAVTMSLGII 592
Cdd:PRK12911 1320 rqekLFTPMPIliNDALQKTLGR--TVMTTATTLSVLL--ILLFVGGGSIFNFAFIMTIGIL 1377
|
|
| actII |
TIGR00833 |
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family ... |
483-619 |
1.15e-03 |
|
Transport protein; The Resistance-Nodulation-Cell Division (RND) Superfamily- MmpL sub family (TC 2.A.6.5)Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. This sub-family includes the S. coelicolor ActII3 protein, which may play a role in drug resistance, and the M. tuberculosis MmpL7 protein, which catalyzes export of an outer membrane lipid, phthiocerol dimycocerosate. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 129913 [Multi-domain] Cd Length: 910 Bit Score: 42.26 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 483 VIATVALAFNM---VMLVALMSILGATL--TLPGIAGIVLtMGMAVDANVLIFSRIREELANGmsvqraIHEGFNRAFTA 557
Cdd:TIGR00833 774 LIGSVALSYLWalgLSVLAFQHILGAELhwSVLAGVFVLL-VALGVDYNMLLVSRIKEESPAG------NRTGIIRALGS 846
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15599016 558 ----ILDANLTsllVGGILYAMGTGP---VKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGgrdfKKLW 619
Cdd:TIGR00833 847 tggvITAAGLV---FAGTMAALASAQltaIAQFGFTVGVGILLDTFIVRSVTVPALTLLLG----RWIW 908
|
|
| Sec_GG |
pfam07549 |
SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export ... |
117-141 |
1.32e-03 |
|
SecD/SecF GG Motif; This family consists of various prokaryotic SecD and SecF protein export membrane proteins. This SecD and SecF proteins are part of the multimeric protein export complex comprising SecA, D, E, F, G, Y, and YajC. SecD and SecF are required to maintain a proton motive force. This alignment encompasses a -GG- motif typically found in N-terminal half of the SecD/SecF proteins.
Pssm-ID: 462205 [Multi-domain] Cd Length: 27 Bit Score: 36.50 E-value: 1.32e-03
10 20
....*....|....*....|....*
gi 15599016 117 LGGSPMKLGLDLSGGVHFLLEVDMD 141
Cdd:pfam07549 2 LFTRGLNLGLDFTGGTVIELQFDQP 26
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
470-613 |
1.52e-03 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 41.90 E-value: 1.52e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 470 VSLFIIVIYRFFG-----VIATVALAFNMVMLVALMSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREELA-NGMSV 543
Cdd:pfam00873 341 IVLVILVMFLFLQnwratLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLVLAIGLVVDDAIVVVENIERVLEeNGLKP 420
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15599016 544 QRAIHEGFNRAFTAILDANLTSLLV-------GGILYAMgtgpVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGGR 613
Cdd:pfam00873 421 LEAAYKSMGEIGGALVAIALVLSAVflpilflGGLTGRI----FRQFAITIVLAILLSVLVALTLTPALCATLLKPR 493
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
494-602 |
5.21e-03 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 39.97 E-value: 5.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 494 VMLVALMSILGATLTL---------PGIAGIVLTMGMAVDANVLIFSRIREELAN-GMSVQRAIHEGFNRAFTAILDANL 563
Cdd:pfam00873 892 IMLTVPLALVGALLALwlrglpnsvYAQVGLILLIGLAVKNAILMVEFANELREQeGKSLEEAILEACRLRLRPILMTAL 971
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 15599016 564 TSLLvgGIL---YAMGTG-----PVkgfAVTMSLGIITSMFTAIMVT 602
Cdd:pfam00873 972 AAIL--GVLplaLSTGAGselqqPL---GIVVFGGLVTSTVLTLLVV 1013
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
494-616 |
8.18e-03 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 39.45 E-value: 8.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599016 494 VMLVALMSILGATL--TLPGI-------AGIVLTMGMAVDANVLIFSRIREELANGMSVQRAIHEGFNRAFTAILdanLT 564
Cdd:PRK09577 895 VMLVVPLGVIGAVLgvTLRGMpndiyfkVGLIATIGLSAKNAILIVEVAKDLVAQRMSLADAALEAARLRLRPIV---MT 971
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 15599016 565 SLLVG-GIL-YAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFG--GRDFK 616
Cdd:PRK09577 972 SLAFGvGVLpLAFASGAASGAQIAIGTGVLGGVITATVLAVFLVPLFFVvvGRLFD 1027
|
|
| |
