|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05321 |
PRK05321 |
nicotinate phosphoribosyltransferase; Provisional |
3-398 |
0e+00 |
|
nicotinate phosphoribosyltransferase; Provisional
Pssm-ID: 235406 [Multi-domain] Cd Length: 400 Bit Score: 713.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 3 ESAFSERIVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQE-DLRLYLPAIREQLEYLAGLAISDEQLAFLERIPF 81
Cdd:PRK05321 1 HTWKADPIIRSLLDTDFYKLTMQQAVLHHYPDAQVEYEFICRNDEvDLAEYIDEIREQLDHLCTLRLTDDELDYLRGLPF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 82 LAPDFIRFLGLFRFNPRYVQTGIENDEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRR 161
Cdd:PRK05321 81 FKPDFLDWLRLFRLNPYEVTVSIDDGQLDIRIEGPWLETILWEVPLLAIISELYFRARSPEVLYAQAKRRLWEKIELLKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 162 easAEELAGFKMADFGTRRRFSYRVHEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPRLIDSQ 241
Cdd:PRK05321 161 ---LPDLSGFKIADFGTRRRFSFEWQEEVVEALKEGLPGAFVGTSNVHLAMKLGLTPIGTMAHEWFMAHQALGPRLRDSQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 242 SAALDCWVREYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGIDPLTKTLVFSDGLD 321
Cdd:PRK05321 238 YAALEDWVREYRGDLGIALTDTIGMDAFLRDFDLYFAKLFDGLRHDSGDPIEWGEKAIAHYEKLGIDPRTKTLVFSDGLD 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15599572 322 LPRALKIYRALQGRINVSFGIGTHFTCDLPGVEPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKHVFQVA 398
Cdd:PRK05321 318 FDKALELYRHFKGRIKLSFGIGTNLTNDFPGVKPLNIVIKLVECNGRPVAKLSDSPGKTMCDDPEFLRYLRQVFGLP 394
|
|
| PncB_like |
cd01401 |
Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate ... |
12-380 |
0e+00 |
|
Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products. This subgroup is present in bacteria, archea and funghi.
Pssm-ID: 238695 [Multi-domain] Cd Length: 377 Bit Score: 621.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 12 QNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQED-LRLYLPAIREQLEYLAGLAISDEQLAFLER-IPFLAPDFIRF 89
Cdd:cd01401 1 RSLLDTDLYKLTMQQAVLHHYPDVQVTYEFTNRSPEDfLEEAAEALREQIDHLANLRFSEEELAYLRRsLPFLKPDYLDY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 90 LGLFRFNPRYVQTGI--ENDEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRREASAEE 167
Cdd:cd01401 81 LELFRLNPEEVVVRLdtGKGQLDIRISGPWKDTILYEVPLLAIVSEVYFRFRDADWDYEEQLEKLEEKLERLLEEAKRRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 168 LAGFKMADFGTRRRFSYRVHEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPRLIDSQSAALDC 247
Cdd:cd01401 161 LNGFRFSDFGTRRRFSYEVQETVLKGLKQAAPGYLTGTSNVHFAMKYGLTPIGTVAHEWFMAHQALTGDLKDSQKAALER 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 248 WVREYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGIDPLTKTLVFSDGLDLPRALK 327
Cdd:cd01401 241 WVREYGGDLGIALTDTFGTDAFLRDFDLYFAKLFDGVRHDSGDPFEWGEKAIAHYEKLGIDPKTKTLVFSDGLDVEKALE 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 15599572 328 IYRALQGRINVSFGIGTHFTCDLP---GVEPMNIVVKMSACNGHPVAKISDTPGKA 380
Cdd:cd01401 321 LYEYFKGRIKVSFGIGTNLTNDFGnkeKSTPLNIVIKLVECNGRPVAKISDSPGKN 376
|
|
| NAPRTase |
TIGR01514 |
nicotinate phosphoribosyltransferase; This model represents nicotinate ... |
10-397 |
2.48e-168 |
|
nicotinate phosphoribosyltransferase; This model represents nicotinate phosphoribosyltransferase, the first enzyme in the salvage pathway of NAD biosynthesis from nicontinate (niacin). Members are primary proteobacterial but also include yeasts and Methanosarcina acetivorans. A related family, apparently non-overlapping in species distribution, is TIGR01513. Members of that family differ in substantially in sequence and have a long C-terminal extension missing from this family, but are proposed also to act as nicotinate phosphoribosyltransferase (see model TIGR01513). [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides]
Pssm-ID: 130578 [Multi-domain] Cd Length: 394 Bit Score: 476.56 E-value: 2.48e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 10 IVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRN-QEDLRLYLPAIREQLEYLAGLAISDEQLAFLER-IPFLAPDFI 87
Cdd:TIGR01514 1 IIRSLLDTDLYKITMHQAVFHNFPDVHVTYEFICRSsQLFLKEAAEALREEISALGNLRFTDDEIEYLKQeLPYLKSDYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 88 RFLGLFRFNP-RYVQTGI-ENDEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRREASA 165
Cdd:TIGR01514 81 DYLRNFRFHPeEQVEVGIdDKGKLDIRISGSWRDTILYEIPLLAIISELYFRFRDAEADYEQQLEVLESKLDQLKAEIAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 166 EEL--AGFKMADFGTRRRFSYRVHEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPrLIDSQSA 243
Cdd:TIGR01514 161 ETMfeNGFRFSEFGTRRRFSLEVQDLVTQGLKQAAPSWLLGTSNVHLAKKLGLKPIGTVAHEWFQGHQAISE-YRNAQKV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 244 ALDCWVREYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGIDPLTKTLVFSDGLDLP 323
Cdd:TIGR01514 240 ALECWINEYDGDLGIALTDTFTTDAFLRDFRPPFADAYDGLRHDSGDPVEWGDKAIAHYQKLGIDPKSKIIIFSDSLDVE 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15599572 324 RALKIYRALQGRINVSFGIGTHFTCDLPGVEPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKHVFQV 397
Cdd:TIGR01514 320 KAIELSHYFKGRVKASFGIGTNLTNDFGKVEPLNIVIKLVECNGNPVAKLSDSPGKTMGEPATFLRALRELFDT 393
|
|
| NAPRTase |
pfam04095 |
Nicotinate phosphoribosyltransferase (NAPRTase) family; Nicotinate phosphoribosyltransferase ... |
171-397 |
8.77e-111 |
|
Nicotinate phosphoribosyltransferase (NAPRTase) family; Nicotinate phosphoribosyltransferase (EC:2.4.2.11) is the rate limiting enzyme that catalyzes the first reaction in the NAD salvage synthesis. This family also includes Pre-B cell enhancing factor that is a cytokine Swiss:P43490. This family is related to Quinolinate phosphoribosyltransferase pfam01729.
Pssm-ID: 397974 [Multi-domain] Cd Length: 235 Bit Score: 324.33 E-value: 8.77e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 171 FKMADFGTRRRFSYRVHEAVVSGlkedFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPRLIDSQSAALDCWVR 250
Cdd:pfam04095 1 FKLHDFGTRRRSSLESQEIVGLA----HLVNFLGTSNVHFAAKYSIPPAGTSAHEWWGAHQELDANLRQFQKDALDLWHA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 251 EYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKL-GIDPLTKTLVFSDGLDLPRALKIY 329
Cdd:pfam04095 77 EYRGNLGIALTDTVTMDAFLKDFDLYFAKLYLGVRPDSGDPVEWGEKLIAHYGSTlNIDGYTKRLIFSDGLDVEKIIELL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15599572 330 RALQG-RINVSFGIGTHFTCDLPG--------VEPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKHVFQV 397
Cdd:pfam04095 157 EYFKGkGFNIAFGIGTNLTQDLNRdtlgfavkATPLNIVIKLVEVNGDPVAKISDSSGKGRCGDPAFVALLRTVFDN 233
|
|
| PncB |
COG1488 |
Nicotinic acid phosphoribosyltransferase [Coenzyme transport and metabolism]; Nicotinic acid ... |
14-380 |
8.77e-40 |
|
Nicotinic acid phosphoribosyltransferase [Coenzyme transport and metabolism]; Nicotinic acid phosphoribosyltransferase is part of the Pathway/BioSystem: NAD biosynthesis
Pssm-ID: 441097 [Multi-domain] Cd Length: 445 Bit Score: 146.83 E-value: 8.77e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 14 LLDTDFYKLTMMQAVLHN-YPNAEVEWEFRCRNQEDLRLYL-PAIREQ-LEYLAGLAISDEQLAFLERIPFLAPDFIRFL 90
Cdd:COG1488 5 ALLTDLYKLTMAQAYLPEgTANRRAVFELFFRRLPFGRGYVvFAGLQRfLKYLENLRFTEEDIAYLRSLGVFDEDFLDYL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 91 GLFRFnpryvqTG-I----ENDEFF-----LRLKGPWLHVILFEVPLLAMISevrnrarYPAATVEQARErlqekfdwLR 160
Cdd:COG1488 85 ADFRF------PGdIravpEGTVVFpgeplLTVEGTLPEAQLLETLLLNILN-------YPTLIATKAAR--------IV 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 161 REASaeelaGFKMADFGTRRRFSYrvhEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHqqlgprliDS 240
Cdd:COG1488 144 QAAG-----GRPLHDFGLRRAHGL---EAAVAAARAAYLAGFAGTSNVLAGRYYGIPSVGTMAHSFVQAH--------DD 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 241 QSAALDCWVREYRGllGIAL-------TDCITTDAFLRDfDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGiDPLTKt 313
Cdd:COG1488 208 ELEAFRAFAEAYPD--GTTLlvdtydtLSGVPNAIELAK-ELLARGGLLGIRLDSGDLAYLSKQARELLDEAG-LPDVR- 282
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15599572 314 LVFSDGLDLPRALKIYRAlQGRINVsFGIGTH----FTCDLPGvepmnIVVKMSACNG----HPVAKISDTPGKA 380
Cdd:COG1488 283 IIASDDLDEYRIAALLEQ-GAPIDV-FGVGTRlvtsSDRPTLG-----FVYKLVAVEGdgewRPVIKLSETPGKK 350
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05321 |
PRK05321 |
nicotinate phosphoribosyltransferase; Provisional |
3-398 |
0e+00 |
|
nicotinate phosphoribosyltransferase; Provisional
Pssm-ID: 235406 [Multi-domain] Cd Length: 400 Bit Score: 713.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 3 ESAFSERIVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQE-DLRLYLPAIREQLEYLAGLAISDEQLAFLERIPF 81
Cdd:PRK05321 1 HTWKADPIIRSLLDTDFYKLTMQQAVLHHYPDAQVEYEFICRNDEvDLAEYIDEIREQLDHLCTLRLTDDELDYLRGLPF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 82 LAPDFIRFLGLFRFNPRYVQTGIENDEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRR 161
Cdd:PRK05321 81 FKPDFLDWLRLFRLNPYEVTVSIDDGQLDIRIEGPWLETILWEVPLLAIISELYFRARSPEVLYAQAKRRLWEKIELLKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 162 easAEELAGFKMADFGTRRRFSYRVHEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPRLIDSQ 241
Cdd:PRK05321 161 ---LPDLSGFKIADFGTRRRFSFEWQEEVVEALKEGLPGAFVGTSNVHLAMKLGLTPIGTMAHEWFMAHQALGPRLRDSQ 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 242 SAALDCWVREYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGIDPLTKTLVFSDGLD 321
Cdd:PRK05321 238 YAALEDWVREYRGDLGIALTDTIGMDAFLRDFDLYFAKLFDGLRHDSGDPIEWGEKAIAHYEKLGIDPRTKTLVFSDGLD 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15599572 322 LPRALKIYRALQGRINVSFGIGTHFTCDLPGVEPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKHVFQVA 398
Cdd:PRK05321 318 FDKALELYRHFKGRIKLSFGIGTNLTNDFPGVKPLNIVIKLVECNGRPVAKLSDSPGKTMCDDPEFLRYLRQVFGLP 394
|
|
| PncB_like |
cd01401 |
Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate ... |
12-380 |
0e+00 |
|
Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products. This subgroup is present in bacteria, archea and funghi.
Pssm-ID: 238695 [Multi-domain] Cd Length: 377 Bit Score: 621.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 12 QNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQED-LRLYLPAIREQLEYLAGLAISDEQLAFLER-IPFLAPDFIRF 89
Cdd:cd01401 1 RSLLDTDLYKLTMQQAVLHHYPDVQVTYEFTNRSPEDfLEEAAEALREQIDHLANLRFSEEELAYLRRsLPFLKPDYLDY 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 90 LGLFRFNPRYVQTGI--ENDEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRREASAEE 167
Cdd:cd01401 81 LELFRLNPEEVVVRLdtGKGQLDIRISGPWKDTILYEVPLLAIVSEVYFRFRDADWDYEEQLEKLEEKLERLLEEAKRRD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 168 LAGFKMADFGTRRRFSYRVHEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPRLIDSQSAALDC 247
Cdd:cd01401 161 LNGFRFSDFGTRRRFSYEVQETVLKGLKQAAPGYLTGTSNVHFAMKYGLTPIGTVAHEWFMAHQALTGDLKDSQKAALER 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 248 WVREYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGIDPLTKTLVFSDGLDLPRALK 327
Cdd:cd01401 241 WVREYGGDLGIALTDTFGTDAFLRDFDLYFAKLFDGVRHDSGDPFEWGEKAIAHYEKLGIDPKTKTLVFSDGLDVEKALE 320
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 15599572 328 IYRALQGRINVSFGIGTHFTCDLP---GVEPMNIVVKMSACNGHPVAKISDTPGKA 380
Cdd:cd01401 321 LYEYFKGRIKVSFGIGTNLTNDFGnkeKSTPLNIVIKLVECNGRPVAKISDSPGKN 376
|
|
| NAPRTase |
TIGR01514 |
nicotinate phosphoribosyltransferase; This model represents nicotinate ... |
10-397 |
2.48e-168 |
|
nicotinate phosphoribosyltransferase; This model represents nicotinate phosphoribosyltransferase, the first enzyme in the salvage pathway of NAD biosynthesis from nicontinate (niacin). Members are primary proteobacterial but also include yeasts and Methanosarcina acetivorans. A related family, apparently non-overlapping in species distribution, is TIGR01513. Members of that family differ in substantially in sequence and have a long C-terminal extension missing from this family, but are proposed also to act as nicotinate phosphoribosyltransferase (see model TIGR01513). [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides]
Pssm-ID: 130578 [Multi-domain] Cd Length: 394 Bit Score: 476.56 E-value: 2.48e-168
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 10 IVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRN-QEDLRLYLPAIREQLEYLAGLAISDEQLAFLER-IPFLAPDFI 87
Cdd:TIGR01514 1 IIRSLLDTDLYKITMHQAVFHNFPDVHVTYEFICRSsQLFLKEAAEALREEISALGNLRFTDDEIEYLKQeLPYLKSDYI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 88 RFLGLFRFNP-RYVQTGI-ENDEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRREASA 165
Cdd:TIGR01514 81 DYLRNFRFHPeEQVEVGIdDKGKLDIRISGSWRDTILYEIPLLAIISELYFRFRDAEADYEQQLEVLESKLDQLKAEIAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 166 EEL--AGFKMADFGTRRRFSYRVHEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPrLIDSQSA 243
Cdd:TIGR01514 161 ETMfeNGFRFSEFGTRRRFSLEVQDLVTQGLKQAAPSWLLGTSNVHLAKKLGLKPIGTVAHEWFQGHQAISE-YRNAQKV 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 244 ALDCWVREYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGIDPLTKTLVFSDGLDLP 323
Cdd:TIGR01514 240 ALECWINEYDGDLGIALTDTFTTDAFLRDFRPPFADAYDGLRHDSGDPVEWGDKAIAHYQKLGIDPKSKIIIFSDSLDVE 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15599572 324 RALKIYRALQGRINVSFGIGTHFTCDLPGVEPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKHVFQV 397
Cdd:TIGR01514 320 KAIELSHYFKGRVKASFGIGTNLTNDFGKVEPLNIVIKLVECNGNPVAKLSDSPGKTMGEPATFLRALRELFDT 393
|
|
| NAPRTase_PncB |
cd01567 |
Nicotinate phosphoribosyltransferase (NAPRTase) family. Nicotinate phosphoribosyltransferase ... |
14-361 |
5.63e-113 |
|
Nicotinate phosphoribosyltransferase (NAPRTase) family. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products.
Pssm-ID: 238801 [Multi-domain] Cd Length: 343 Bit Score: 333.85 E-value: 5.63e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 14 LLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQEDLRLY--LPAIREQLEYLAGLAISDEQLAFL----------ERIPF 81
Cdd:cd01567 1 LLDTDLYKLTMMQAYLYPYPNTRVVFEFTFRSNPFGGDYivFAGLEEVLKLLENLRFTEEEIEYLkkllifgeffLYLLF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 82 LAPDFIRFLGLFRFNPRYVQtgiendEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDwlrr 161
Cdd:cd01567 81 LGKLPLEIYALPEGTVVFPK------EPLLTIEGPWPEAGLLETPLLAIWNEATSIATKAARKKLAAGGLLETKDN---- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 162 easaEELAGFKMADFGTRRRFSYrvhEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLgprlIDSQ 241
Cdd:cd01567 151 ----LEELGFKLHDFGTRRRHSP---EAALSGGRAALIGGFGGTSNVAAAKKLGIPPIGTMAHSWIQAFGAL----EEAA 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 242 SAALDCWVREYRGLLGIALTDCITTD-AFLRDFDLYFAKL----FDGLRHDSGDPLLWAEKTIAHYLKLGIDPLTKTLVF 316
Cdd:cd01567 220 FEAFARWLPQFGGGLGIALIDTYDTDnGFLNALKLAKALGagggLLGVRLDSGDPVELIKKVRKHLDELGIDLNKKKIII 299
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 15599572 317 SDGLDLPRALKIYRALQGRINVSFGIGTHFTCDLpGVEPMNIVVK 361
Cdd:cd01567 300 SGDLDTEEAIELLLEQGASPNDAFGVGTSLTNDL-GRPPLGFVYK 343
|
|
| NAPRTase |
pfam04095 |
Nicotinate phosphoribosyltransferase (NAPRTase) family; Nicotinate phosphoribosyltransferase ... |
171-397 |
8.77e-111 |
|
Nicotinate phosphoribosyltransferase (NAPRTase) family; Nicotinate phosphoribosyltransferase (EC:2.4.2.11) is the rate limiting enzyme that catalyzes the first reaction in the NAD salvage synthesis. This family also includes Pre-B cell enhancing factor that is a cytokine Swiss:P43490. This family is related to Quinolinate phosphoribosyltransferase pfam01729.
Pssm-ID: 397974 [Multi-domain] Cd Length: 235 Bit Score: 324.33 E-value: 8.77e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 171 FKMADFGTRRRFSYRVHEAVVSGlkedFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHQQLGPRLIDSQSAALDCWVR 250
Cdd:pfam04095 1 FKLHDFGTRRRSSLESQEIVGLA----HLVNFLGTSNVHFAAKYSIPPAGTSAHEWWGAHQELDANLRQFQKDALDLWHA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 251 EYRGLLGIALTDCITTDAFLRDFDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKL-GIDPLTKTLVFSDGLDLPRALKIY 329
Cdd:pfam04095 77 EYRGNLGIALTDTVTMDAFLKDFDLYFAKLYLGVRPDSGDPVEWGEKLIAHYGSTlNIDGYTKRLIFSDGLDVEKIIELL 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 15599572 330 RALQG-RINVSFGIGTHFTCDLPG--------VEPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKHVFQV 397
Cdd:pfam04095 157 EYFKGkGFNIAFGIGTNLTQDLNRdtlgfavkATPLNIVIKLVEVNGDPVAKISDSSGKGRCGDPAFVALLRTVFDN 233
|
|
| PRTase_typeII |
cd00516 |
Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an ... |
18-361 |
5.75e-59 |
|
Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate phosphoribosyltransferase (NAPRTase), to be used in the synthesis of NAD. QAPRTase catalyses the reaction of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg2+ to produce nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide, an important step in the de novo synthesis of NAD. NAPRTase catalyses a similar reaction leading to NAMN and pyrophosphate, using nicotinic acid an PPRP as substrates, used in the NAD salvage pathway.
Pssm-ID: 238286 [Multi-domain] Cd Length: 281 Bit Score: 193.23 E-value: 5.75e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 18 DFYKLTMMQAvlHNYPNAEVEWEFRCRNqedlrlylpairEQLEYLAGLaisDEQLAFLERIPFlaPDFIRFLGLFRFNP 97
Cdd:cd00516 1 DLYKLTMIQA--YPPPDTRATAEFTARE------------DPYGVLAGL---EEALELLELLRF--PGPLVILAVPEGTV 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 98 ryvqtgIENDEFFLRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARErlqekfdwlrreasaeelAGFKMADFG 177
Cdd:cd00516 62 ------VEPGEPLLTIEGPARELLLLERVLLNLLQRLSGIATATARYVEAAKG------------------ANTKVHDFG 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 178 TRRRFSyrvhEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHqqlgprLIDSQSAALDCWVREyrglLG 257
Cdd:cd00516 118 TRKTTP----GLRLLEKYAVLIGGGDGHRNGLSDAILIKDNHGTMAHSIIQAF------GELAAVKALRRWLPE----LF 183
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 258 IALTDCITTDaFLRDFDLYFAKLFDGLRHDSG-----DPLLWAEKTIAHYlkLGIDPLTKTLVFSDGLDLPRALKIyrAL 332
Cdd:cd00516 184 IALIDVEVDT-LEEALEAAKAGGADGIRLDSGspeelDPAVLILKARAHL--DGKGLPRVKIEASGGLDEENIRAY--AE 258
|
330 340
....*....|....*....|....*....
gi 15599572 333 QGriNVSFGIGTHFTCDlpgvEPMNIVVK 361
Cdd:cd00516 259 TG--VDVFGVGTLLHSA----PPLDIVLK 281
|
|
| NAPRTase_N |
pfam17767 |
Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain; Nicotinate ... |
15-132 |
7.46e-41 |
|
Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain; Nicotinate phosphoribosyltransferase (EC:2.4.2.11) is the rate limiting enzyme that catalyzes the first reaction in the NAD salvage synthesis. This is the N-terminal domain of the enzyme.
Pssm-ID: 465494 [Multi-domain] Cd Length: 125 Bit Score: 140.73 E-value: 7.46e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 15 LDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQEDLRLY--LPAIREQLEYLAGLAISDEQLAFLER-IPFLAPDFIRFLG 91
Cdd:pfam17767 1 LDTDLYKLTMAQAYFKNGPDVQVVFEFFNRTNPFGGLYavFAGLEEQIEFLENLRFTEEEIEYLRRsLPYFKPDFLDYLR 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 15599572 92 LFRFNPRYV----QTGIENDEFFLRLKGPWLHVILFEVPLLAMIS 132
Cdd:pfam17767 81 NFRFDPSIVavpeGEVVFPGEPLLRIEGPWLETILLETPLLAIVN 125
|
|
| PncB |
COG1488 |
Nicotinic acid phosphoribosyltransferase [Coenzyme transport and metabolism]; Nicotinic acid ... |
14-380 |
8.77e-40 |
|
Nicotinic acid phosphoribosyltransferase [Coenzyme transport and metabolism]; Nicotinic acid phosphoribosyltransferase is part of the Pathway/BioSystem: NAD biosynthesis
Pssm-ID: 441097 [Multi-domain] Cd Length: 445 Bit Score: 146.83 E-value: 8.77e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 14 LLDTDFYKLTMMQAVLHN-YPNAEVEWEFRCRNQEDLRLYL-PAIREQ-LEYLAGLAISDEQLAFLERIPFLAPDFIRFL 90
Cdd:COG1488 5 ALLTDLYKLTMAQAYLPEgTANRRAVFELFFRRLPFGRGYVvFAGLQRfLKYLENLRFTEEDIAYLRSLGVFDEDFLDYL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 91 GLFRFnpryvqTG-I----ENDEFF-----LRLKGPWLHVILFEVPLLAMISevrnrarYPAATVEQARErlqekfdwLR 160
Cdd:COG1488 85 ADFRF------PGdIravpEGTVVFpgeplLTVEGTLPEAQLLETLLLNILN-------YPTLIATKAAR--------IV 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 161 REASaeelaGFKMADFGTRRRFSYrvhEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHqqlgprliDS 240
Cdd:COG1488 144 QAAG-----GRPLHDFGLRRAHGL---EAAVAAARAAYLAGFAGTSNVLAGRYYGIPSVGTMAHSFVQAH--------DD 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 241 QSAALDCWVREYRGllGIAL-------TDCITTDAFLRDfDLYFAKLFDGLRHDSGDPLLWAEKTIAHYLKLGiDPLTKt 313
Cdd:COG1488 208 ELEAFRAFAEAYPD--GTTLlvdtydtLSGVPNAIELAK-ELLARGGLLGIRLDSGDLAYLSKQARELLDEAG-LPDVR- 282
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 15599572 314 LVFSDGLDLPRALKIYRAlQGRINVsFGIGTH----FTCDLPGvepmnIVVKMSACNG----HPVAKISDTPGKA 380
Cdd:COG1488 283 IIASDDLDEYRIAALLEQ-GAPIDV-FGVGTRlvtsSDRPTLG-----FVYKLVAVEGdgewRPVIKLSETPGKK 350
|
|
| NAPRTase_put |
TIGR01513 |
putative nicotinate phosphoribosyltransferase; A deep split separates two related families of ... |
15-379 |
9.86e-30 |
|
putative nicotinate phosphoribosyltransferase; A deep split separates two related families of proteins, one of which includes experimentally characterized examples of nicotinate phosphoribosyltransferase, an the first enzyme of NAD salvage biosynthesis. This model represents the other family. Members have a different (longer) spacing of several key motifs and have an additional C-terminal domain of up to 100 residues. One argument suggesting that this family represents the same enzyme is that no species has a member of both families. Another is that the gene encoding this protein is located near other NAD salvage biosynthesis genes in Nostoc and in at least four different Gram-positive bacteria. NAD and NADP are ubiquitous in life. Most members of this family are Gram-positive bacteria. An additional set of mutually closely related archaeal sequences score between the trusted and noise cutoffs. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides]
Pssm-ID: 273666 [Multi-domain] Cd Length: 443 Bit Score: 119.39 E-value: 9.86e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 15 LDTDFYKLTMMQAVL-HNYPNAEVEWEFRCRNQEDLRLYLPA--IREQLEYLAGLAISDEQLAFLERIPFLAPDFIRFLG 91
Cdd:TIGR01513 2 LLTDLYELTMAQGYFrEGKANQPAVFEVFFRKLPFGRGYAVFagLEDLLEFLENFRFDAEDIEYLASLGIFDDAFLDYLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 92 LFRFNPRyVQTGIENDEFF-----LRLKGPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERlqekfdwlrreasae 166
Cdd:TIGR01513 82 EFRFSGT-VRALPEGSLVFpneplLQVEGPLIEAQLLETLVLNIINFQTLIATKAARIVLAAGGK--------------- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 167 elagfKMADFGTRRRFSYrvhEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHqqlgprliDSQSAALd 246
Cdd:TIGR01513 146 -----PLLEFGLRRAQGP---DAALKAARAAYIGGADGTSNVLAGRLYGIPVSGTMAHSFVMSF--------DNELAAF- 208
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 247 cwvREYRGLLGIALTDCITTDAFLRDFDLYFAKLFD---------GLRHDSGDPLLWAEKTIAHYLKLGidpLTKTLVF- 316
Cdd:TIGR01513 209 ---RAYAKLYPKATVLLVDTYDTLRSGLPNAIAVAKelgeqgkvvGVRIDSGDLLYLSKQARKQLDAAG---LTQVKIVv 282
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 15599572 317 SDGLDlPRALKIYRALQGRINVsFGIGTHF-TCdlPGVEPMNIVVKMSACNGHPVAKISDTPGK 379
Cdd:TIGR01513 283 SNDLD-ENSIAALKAEGAPIDV-YGVGTSLvTA--SDAPALGGVYKLVAYEGRPVMKLSENPEK 342
|
|
| NAPRTase_A |
cd01570 |
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate ... |
15-348 |
1.61e-20 |
|
Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction in the NAD salvage synthesis. This salvage pathway serves to recycle NAD degradation products. This subgroup is present in bacteria and eukaryota (except funghi).
Pssm-ID: 238804 [Multi-domain] Cd Length: 327 Bit Score: 91.48 E-value: 1.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 15 LDTDFYKLTMMQAVLH-NYPNAEVEWEFRCRNQEDLRLYLPA--IREQLEYLAGLAISDEQLAFLERIPFLAPDFIRFLG 91
Cdd:cd01570 2 LLTDLYQLTMAQAYWKeGKHNKPAVFELFFRKLPFGGGYAVFagLEELLEYLENFRFTEEDIDYLRSLGIFDEEFLDYLR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 92 LFRF--NPRYVQTG--IENDEFFLRLKGPWLHVILFEVPLLAMISevrnrarYPAATVEQAReRLqekfdwlrREASAEE 167
Cdd:cd01570 82 GFRFtgTIYAIPEGevVFPNEPLLTVEGPLIEAQLLETLLLNLIN-------FQTLIATKAA-RV--------RLAAGGR 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 168 lagfKMADFGTRRRFSYrvhEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHqqlgprliDSQSAALDC 247
Cdd:cd01570 146 ----PLLEFGLRRAQGP---DAALSAARAAYIGGFDGTSNVLAGKLYGIPVSGTMAHSFVQAF--------DDELAAFRA 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 248 WVREYRGLLgIALTDciTTD-----------AFLRDFDLYFaKLFdGLRHDSGDPLLWAEKTIAHYLKLGidpLTKTLVF 316
Cdd:cd01570 211 FAEAYPDNF-TLLVD--TYDtlrsglpnaiaVAKELGALGY-RLV-GVRIDSGDLAYLSKEARKMLDEAG---LTKVKIV 282
|
330 340 350
....*....|....*....|....*....|....*.
gi 15599572 317 -SDGLD--LPRALKIYRAlqgRINVsFGIGTHF-TC 348
Cdd:cd01570 283 aSNDLDeyTIAALNAQGA---PIDA-FGVGTRLvTS 314
|
|
| PRK09243 |
PRK09243 |
nicotinate phosphoribosyltransferase; Validated |
15-380 |
2.19e-19 |
|
nicotinate phosphoribosyltransferase; Validated
Pssm-ID: 236426 [Multi-domain] Cd Length: 464 Bit Score: 89.45 E-value: 2.19e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 15 LDTDFYKLTMMQAVLHNYPNAEV---EWEFRcRNQEDLRLYLPAIREQ-LEYLAGLAISDEQLAFLERIPFLAPDFIRFL 90
Cdd:PRK09243 11 LLTDLYELTMAQAYLRDGIHNRRavfELFFR-KLPFGRGYAVFAGLERlLEYLENLRFTEEDIEYLRSLGIFDEDFLDYL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 91 GLFRFnpryvqTG-I----ENDEFF-----LRLKGPWLHVILFEVPLLAMI---SEVRNRArypAATVEQARERlqekfd 157
Cdd:PRK09243 90 RNFRF------TGdVravpEGELVFpneplLRVEGPLAEAQLLETLLLNIInfqTLIATKA---ARIVSAAGGR------ 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 158 wlrreasaeelagfKMADFGTRRRFSYrvhEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAHqqlgprl 237
Cdd:PRK09243 155 --------------PLLEFGSRRAQGP---DAAVWAARAAYIGGFDATSNVLAGKRYGIPVSGTMAHSFVQAF------- 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 238 iDSQSAALDCWVREYRgllgialTDCI----TTD--------------AFLRDFDLYfaklfdGLRHDSGDpLLWAEKTI 299
Cdd:PRK09243 211 -DDEYEAFRAYAETYP-------DNTVllvdTYDtlksgvpnaikvakELGDGIELG------GVRIDSGD-LAYLSKKV 275
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 300 AHYL-KLGidpLTKTLVF-SDGLD--LPRALKiyraLQG-RINVsFGIGTHF-TCDlpGVEPMNIVVKMSACNGH----P 369
Cdd:PRK09243 276 RKMLdEAG---FTDTKIVaSNDLDeyTIASLK----LQGaPIDG-FGVGTKLvTGS--DAPALGGVYKLVAIEGEggmiP 345
|
410
....*....|.
gi 15599572 370 VAKISDTPGKA 380
Cdd:PRK09243 346 KIKLSNSPEKV 356
|
|
| PRK12484 |
PRK12484 |
nicotinate phosphoribosyltransferase; Provisional |
15-386 |
7.68e-18 |
|
nicotinate phosphoribosyltransferase; Provisional
Pssm-ID: 237112 [Multi-domain] Cd Length: 443 Bit Score: 84.80 E-value: 7.68e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 15 LDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQEDLRLYLPA--IREQLEYLAGLAISDEQLAFLERIPFLAPDFIRFLGL 92
Cdd:PRK12484 6 LLTDLYEVTMANAYLREGMSAPATFSLFYRKLPDGRGFLIAagLADVVEFLEAFRFDEQDLRYLRGLNQFSEEFLAWLAG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 93 FRF--NPRYVQTG--IENDEFFLRLKGPWLHVILFEVPLLAMISevrnrarYPAATVEQARErlqekfdwLRREAsaeel 168
Cdd:PRK12484 86 LRFtgDVRAVPEGtvVFPNEPLLEVTAPLIEAQLVETFLLNQIN-------HQSLIASKAAR--------CVLAA----- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 169 AGFKMADFGTRRRFSYrvhEAVVSGLKEDFPGCFVGTSNVHLARKLDLKPLGTMAHEWLMAhqqlgprlIDSQSAALDCW 248
Cdd:PRK12484 146 AGRPVVDFGARRAHGT---DAACYVARASYLAGAAGTSNVLAARQYGIPASGTMAHSFVEA--------FPDEVAAFRAF 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 249 VREYRGLLgIALTDCITTDA-------FLRDFDLYFAKLfdGLRHDSGDPLLWAEKTIAHYLKLGidpLTKT-LVFSDGL 320
Cdd:PRK12484 215 ARLYPDAT-TLLVDTYDTLRgvrnaieVAKELGNRFDPR--GVRLDSGDLAELSKATRAILDAAG---LEQVkIVASGGL 288
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15599572 321 DLPRALKIYRAlQGRINVsFGIGTHF--TCDLPGvepMNIVVKMSACNGHPVAKISD----TPGKAQC-RDPD 386
Cdd:PRK12484 289 DEYRIAALLAA-GAPIDG-FGVGTRLgvAADAPV---LDSAYKLVAYEGRGVTKLSSgkvtYPGRKQVfRLYE 356
|
|
| PRK08662 |
PRK08662 |
nicotinate phosphoribosyltransferase; Reviewed |
108-224 |
9.78e-03 |
|
nicotinate phosphoribosyltransferase; Reviewed
Pssm-ID: 236328 [Multi-domain] Cd Length: 343 Bit Score: 37.93 E-value: 9.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15599572 108 EFFLRLKGPWLHVILFEVPLLAMIsevrnraRYPAATVEQARErlqekfdwlrreasAEELAGFK-MADFGTRRrfsyrV 186
Cdd:PRK08662 85 EPVMRIEGPYLEFGIYETALLGIL-------AHASGIATAAAR--------------CKEAAGDKpVLSFGARH-----V 138
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 15599572 187 HEAVvSGLKED--FPGCFVGTSNVHLARKLDLKPLGTMAH 224
Cdd:PRK08662 139 HPAI-APMMDRaaYIGGCDGVSGVLGAELLGIEPSGTMPH 177
|
|
| |
