|
Name |
Accession |
Description |
Interval |
E-value |
| PBP1_ABC_LIVBP-like |
cd06342 |
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active ... |
30-364 |
1.22e-142 |
|
type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); This subgroup includes the type 1 periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine). This subgroup also includes a leucine-specific binding protein (or LivK), which is very similar in sequence and structure to leucine-isoleucine-valine binding protein (LIVBP). ABC-type active transport systems are transmembrane proteins that function in the transport of diverse sets of substrates across extra- and intracellular membranes, including carbohydrates, amino acids, inorganic ions, dipeptides and oligopeptides, metabolic products, lipids and sterols, and heme, to name a few.
Pssm-ID: 380565 [Multi-domain] Cd Length: 334 Bit Score: 408.07 E-value: 1.22e-142
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDqDKAIAVVGHFCSSST 109
Cdd:cd06342 1 KIGVAGPLTGPNAALGQDIRNGAELAVDEINAKGGGLGFKIELVAQDDACDPAQAVAAAQKLVA-DGVVAVIGHYNSGAA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQL 189
Cdd:cd06342 80 IAAAPIYAEAGIPMISPSATNPKLTEQGYKNFFRVVGTDDQQGPAAADYAAKTLKAKRVAVIHDGTAYGKGLADAFKKAL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGpqY 269
Cdd:cd06342 160 KALGGTVVGREGITPGTTDFSALLTKIKAANPDAVYFGGYYPEAGLLLRQLREAGLKAPFMGGDGIVSPDFIKAAGD--A 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 270 VKGVLMTFGADP-RLIPDGKAVVEKFRA-GGFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWLKSHPVQTVMGKKE 347
Cdd:cd06342 238 AEGVYATTPGAPpEKLPAAKAFLKAYKAkFGEPPGAYAAYAYDAAQVLLAAIEKAGSTDRAAVAAALRATDFDGVTGTIS 317
|
330
....*....|....*..
gi 15600106 348 WDKKGDLKVSDYVVYEW 364
Cdd:cd06342 318 FDAKGDLTGPAFTVYQV 334
|
|
| PRK15404 |
PRK15404 |
high-affinity branched-chain amino acid ABC transporter substrate-binding protein; |
3-369 |
1.69e-138 |
|
high-affinity branched-chain amino acid ABC transporter substrate-binding protein;
Pssm-ID: 237959 [Multi-domain] Cd Length: 369 Bit Score: 398.63 E-value: 1.69e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 3 KKLFRKGILALAVSsvMGLSTHALADVV-IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEP 81
Cdd:PRK15404 1 MKSKGKTLLAGCIA--LALSHAALADDIkIAIVGPMSGPVAQYGDMEFTGARQAIEDINAKGGIKGDKLEGVEYDDACDP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 82 KQAVAVANRLVDqDKAIAVVGHFCSSSTIPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVN 161
Cdd:PRK15404 79 KQAVAVANKVVN-DGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLIFRTIGLDSDQGPTAAKYILE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 162 VLKAKKVAVIHDKDTYGQGLADATRAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMR 241
Cdd:PRK15404 158 KVKPKRIAVLHDKQQYGEGLARSVKDGLKKAGANVVFFEGITAGDKDFSALIAKLKKENVDFVYYGGYHPEMGQILRQAR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 242 EQGLTARFMSDDGVVTDELATTAGGPqyVKGVLMTFGADPRLIPDGKAVVEKFRAGGFEPEG-YTLYSYASIQSLAAAFN 320
Cdd:PRK15404 238 EAGLKTQFMGPEGVGNKSLSNIAGPA--SEGMLVTLPKRYDQDPANKAIVDAFKAKKQDPSGpFVWTTYAAVQSLAAGIN 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 15600106 321 GAGANDPAKAAEWLKSHPVQTVMGKKEWDKKGDLKVSDYVVYEWDDKGK 369
Cdd:PRK15404 316 RAGSDDPAKVAKYLKANTFDTVIGPLSWDEKGDLKGFEFGVFEWHADGT 364
|
|
| LivK |
COG0683 |
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid ... |
27-370 |
6.82e-90 |
|
ABC-type branched-chain amino acid transport system, periplasmic component [Amino acid transport and metabolism];
Pssm-ID: 440447 [Multi-domain] Cd Length: 314 Bit Score: 272.96 E-value: 6.82e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 27 ADVVIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCS 106
Cdd:COG0683 2 DPIKIGVLLPLTGPYAALGQPIKNGAELAVEEINAAGGVLGRKIELVVEDDASDPDTAVAAARKLIDQDKVDAIVGPLSS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 107 SSTIPASEVYDEAGIIAITPGSTNPQVTERGLSG-MFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADAT 185
Cdd:COG0683 82 GVALAVAPVAEEAGVPLISPSATAPALTGPECSPyVFRTAPSDAQQAEALADYLAKKLGAKKVALLYDDYAYGQGLAAAF 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 186 RAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMsddgvvtdelattag 265
Cdd:COG0683 162 KAALKAAGGEVVGEEYYPPGTTDFSAQLTKIKAAGPDAVFLAGYGGDAALFIKQAREAGLKGPLN--------------- 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 266 gpqyvkgvlmtfgadprlipdgKAVVEKFRA-GGFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWLKSHPVQTVMG 344
Cdd:COG0683 227 ----------------------KAFVKAYKAkYGREPSSYAAAGYDAALLLAEAIEKAGSTDREAVRDALEGLKFDGVTG 284
|
330 340
....*....|....*....|....*.
gi 15600106 345 KKEWDKKGDLkVSDYVVYEWDDKGKY 370
Cdd:COG0683 285 PITFDPDGQG-VQPVYIVQVKADGKF 309
|
|
| PBP1_ABC_LivK_ligand_binding-like |
cd06347 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-353 |
1.28e-80 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380570 [Multi-domain] Cd Length: 334 Bit Score: 249.77 E-value: 1.28e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd06347 1 KIGVIGPLTGEAAAYGQPALNGAELAVDEINAAGGILGKKIELIVYDNKSDPTEAANAAQKLIDEDKVVAIIGPVTSSIA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVTErGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDK-DTYGQGLADATRAQ 188
Cdd:cd06347 81 LAAAPIAQKAKIPMITPSATNPLVTK-GGDYIFRACFTDPFQGAALAKFAYEELGAKKAAVLYDVsSDYSKGLAKAFKEA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 189 LNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELAtTAGGPQ 268
Cdd:cd06347 160 FEKLGGEIVAEETYTSGDTDFSAQLTKIKAANPDVIFLPGYYEEAALIIKQARELGITAPILGGDGWDSPELL-ELGGDA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 269 YVKGVLMTFGADPRLIPDGKAVVEKFRA-GGFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWLKSHP-VQTVMGKK 346
Cdd:cd06347 239 VEGVYFTTHFSPDDPSPEVQEFVKAYKAkYGEPPNAFAALGYDAVMLLADAIKRAGSTDPEAIRDALAKTKdFEGVTGTI 318
|
....*..
gi 15600106 347 EWDKKGD 353
Cdd:cd06347 319 TFDPNGN 325
|
|
| PBP1_ABC_transporter_LIVBP-like |
cd06268 |
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the ... |
31-315 |
1.44e-79 |
|
periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily; Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.
Pssm-ID: 380492 [Multi-domain] Cd Length: 298 Bit Score: 246.08 E-value: 1.44e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd06268 2 IGVVVPLTGPYADYGEEILRGVALAVEEINAAGGINGRKLELVIADDQGDPETAVAVARKLVDDDKVLAVVGHYSSSVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd06268 82 AAAPIYQEAGIPLISPGSTAPELTEGGGPYVFRTVPSDAMQAAALADYLAKKLKGKKVAILYDDYDYGKSLADAFKKALK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 191 KLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDElaTTAGGPQYV 270
Cdd:cd06268 162 ALGGEIVAEEDFPLGTTDFSAQLTKIKAAGPDVLFLAGYGADAANALKQARELGLKLPILGGDGLYSPE--LLKLGGEAA 239
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 15600106 271 KGVLMTFGADPRL-IPDGKAVVEKFRA-GGFEPEGYTLYSYASIQSL 315
Cdd:cd06268 240 EGVVVAVPWHPDSpDPPKQAFVKAYKKkYGGPPSWRAATAYDATQAL 286
|
|
| PBP1_ABC_HAAT-like |
cd06349 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-312 |
6.47e-74 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380572 [Multi-domain] Cd Length: 338 Bit Score: 232.84 E-value: 6.47e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd06349 1 KIGVSGPLTGDNAEYGQQFKNGVELAVDEINAAGGVNGRKLELVVYDDQGDPKEAVNIAQKFVSDDKVVAVIGDFSSSCS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVTERGlSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQL 189
Cdd:cd06349 81 MAAAPIYEEAGLVQISPTASHPDFTKGG-DYVFRNSPTQAVEAPFLADYAVKKLGAKKIAIIYLNTDWGVSAADAFKKAA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGPqy 269
Cdd:cd06349 160 KALGGEIVATEAYLPGTKDFSAQITKIKNANPDAIYLAAYYNDAALIAKQARQLGWDVQIFGSSSLYSPEFIELAGDA-- 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 15600106 270 VKGVLMTFGADPRL-IPDGKAVVEKFRAG-GFEPEGYTLYSYASI 312
Cdd:cd06349 238 AEGVYLSSPFFPESpDPEVKEFVKAYKAKyGEDPDDFAARAYDAV 282
|
|
| PBP1_ABC_ligand_binding-like |
cd19980 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-361 |
2.95e-72 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380635 [Multi-domain] Cd Length: 334 Bit Score: 228.26 E-value: 2.95e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd19980 2 IGVIAPLSGPVAALGQQVLNGAKLAVEEINAKGGVLGRKLELVVEDDKCPPAEGVAAAKKLITDDKVPAIIGAWCSSVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd19980 82 AVMPVAERAKVPLVVEISSAPKITEGGNPYVFRLNPTNSMLAKAFAKYLADKGKPKKVAFLAENDDYGRGAAEAFKKALK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 191 KLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGP--Q 268
Cdd:cd19980 162 AKGVKVVATEYFDQGQTDFTTQLTKLKAANPDAIFVVAETEDGALILKQARELGLKQQLVGTGGTTSPDLIKLAGDAaeG 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 269 YVKGVLMTFGADPrliPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSLAAAFNGAGANDP-AKAAEWLKSHPVQTVMGKK 346
Cdd:cd19980 242 VYGASIYAPTADN---PANKAFVAAYKKKyGEPPDKFAALGYDAVMVIAEAIKKAGSTDPeKIRAAALKKVDYKGPGGTI 318
|
330
....*....|....*
gi 15600106 347 EWDKKGDLKVSDYVV 361
Cdd:cd19980 319 KFDEKGQAHKNVVLV 333
|
|
| PBP1_ABC_ligand_binding-like |
cd19984 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-309 |
8.23e-70 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380639 [Multi-domain] Cd Length: 296 Bit Score: 220.94 E-value: 8.23e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd19984 2 IGVILPLTGDAASYGEDMKNGIELAVEEINAAGGINGKKIELIYEDSKCDPKKAVSAANKLINVDKVKAIIGGVCSSETL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGlSGMFRMCGRDDQQGVVAGDYIVNVLKaKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd19984 82 AIAPIAEQNKVVLISPGASSPEITKAG-DYIFRNYPSDAYQGKVLAEFAYNKLY-KKVAILYENNDYGVGLKDVFKKEFE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 191 KLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGgpQYV 270
Cdd:cd19984 160 ELGGKIVASESFEQGETDFRTQLTKIKAANPDAIFLPGYPKEGGLILKQAKELGIKAPILGSDGFEDPELLEIAG--EAA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 15600106 271 KGVLMTFGA-DPRLIPDGKAVVEKFRAG-GFEPEGYTLYSY 309
Cdd:cd19984 238 EGVIFTYPAfDDSSEKKQKFFFYRYKEKyGKEPDIYAALAY 278
|
|
| PBP1_ABC_HAAT-like |
cd19988 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-312 |
1.63e-68 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380643 [Multi-domain] Cd Length: 302 Bit Score: 217.91 E-value: 1.63e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd19988 1 KIGVFGPLSGDAAPYGQAMLQGAELAVEEINAAGGILGIPIELVVEDDEGLPAASVSAAKKLIYQDKVWAIIGSINSSCT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQL 189
Cdd:cd19988 81 LAAIRVALKAGVPQINPGSSAPTITESGNPWVFRCTPDDRQQAYALVDYAFEKLKVTKIAVLYVNDDYGRGGIDAFKDAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGpqY 269
Cdd:cd19988 161 KKYGIEVVVEESYNRGDKDFSPQLEKIKDSGAQAIVMWGQYTEGALIAKQARELGLKQPLFGSDGLVTPKFIELAGD--A 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 15600106 270 VKGVLMTFGADPRLIPDG-KAVVEKFRAG-GFEPEGYTLYSYASI 312
Cdd:cd19988 239 AEGAIATTPFLPDSDDPKvSAFVEKYKKRyGEEPDVFAAQAYDAM 283
|
|
| PBP1_ABC_HAAT-like |
cd06344 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
28-355 |
5.89e-64 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380567 [Multi-domain] Cd Length: 332 Bit Score: 207.08 E-value: 5.89e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 28 DVVIGVAGPHTGANasfgEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSS 107
Cdd:cd06344 1 DIVIGVAWPFAPDG----DLFLEGVELAVEEINAAGGVLGRKIRLVEYDDEASVDKGLAIAQRFADNPDVVAVIGHRSSY 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 108 STIPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNvLKAKKVAVIHDKDTYGQGLADATRA 187
Cdd:cd06344 77 VAIPASIIYERAGLLMLSPGATAPKLTQHGFKYIFRNIPSDEDIARQLARYAAR-QGYKRIVIYYDDDSYGKGLANAFEE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 188 QLNKLGVKEVLYEGLTRGEKDFNALVTKIRA-SGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGg 266
Cdd:cd06344 156 EARELGITIVDRRSYSSDEEDFRRLLSKWKAlDFFDAIFLAGSMPEGAEFIKQARELGIKVPIIGGDGLDSPELIEIAG- 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 267 pQYVKGVLMTFGADPRL-IPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWLKS-HPVQTVM 343
Cdd:cd06344 235 -KAAEGVVVATVFDPDDpRPEVRAFVEAFRKKyGREPDVWAAQGYDAVKLLAEAIEKAGSTVPAKIASALRFlENWEGVT 313
|
330
....*....|..
gi 15600106 344 GKKEWDKKGDLK 355
Cdd:cd06344 314 GTYSFDANGDVV 325
|
|
| PBP1_ABC_ligand_binding-like |
cd06346 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-309 |
1.13e-62 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380569 [Multi-domain] Cd Length: 314 Bit Score: 203.18 E-value: 1.13e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd06346 2 IGALLPLTGPLASLGPPMLAAAELAVEEINAAGGVLGKKVELVVEDSQTDPTAAVDAARKLVDVEGVPAIVGAASSGVTL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGLSGM-FRMCGRDDQQGVVAGDYIVNvLKAKKVAVIHDKDTYGQGLADATRAQL 189
Cdd:cd06346 82 AVASVAVPNGVVQISPSSTSPALTTLEDKGYvFRTAPSDALQGVVLAQLAAE-RGFKKVAVIYVNNDYGQGLADAFKKAF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLG---VKEVLYEgltRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTA-RFMSDDGVVTDELATTAg 265
Cdd:cd06346 161 EALGgtvTASVPYE---PGQTSYRAELAQAAAGGPDALVLIGYPEDGATILREALELGLDFtPWIGTDGLKSDDLVEAA- 236
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 15600106 266 GPQYVKGVLMTfGADPRLIPDGKAVVEKFRA-GGFEPEGYTLYSY 309
Cdd:cd06346 237 GAEALEGMLGT-APGSPGSPAYEAFAAAYKAeYGDDPGPFAANAY 280
|
|
| PBP1_ABC_ligand_binding-like |
cd06340 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-364 |
4.97e-62 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380563 [Multi-domain] Cd Length: 352 Bit Score: 202.79 E-value: 4.97e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGI---NGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCS 106
Cdd:cd06340 1 KIGVLYPLSGPLALIGQEAKRGAELAVDEINAAGGIkslGGAKIELVVADTQSDPEVAASEAERLITQEGVVAIIGAYSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 107 SSTIPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKA-----KKVAVIHDKDTYGQGL 181
Cdd:cd06340 81 SVTLAASQVAERYGVPFVTASAVADEITERGFKYVFRTAPTASQFAEDAVDFLKELAKKkgkkiKKVAIIYEDSAFGTSV 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 182 ADATRAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTAR-FMSDDGVVTDEL 260
Cdd:cd06340 161 AKGLKKAAKKAGLEVVLDEPYPAGATDLSSEVLKLKAAKPDVVFATSYTNDAILLLRTMKELGFKPKaIIGVGGGYSDPE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 261 ATTAGGP--QYVKGVLMTFGADPRLIPDGKAVVEKFRA-GGFEPEGYTLYSYASIQSLAAAFNGAGANDP----AKAAEW 333
Cdd:cd06340 241 FLKALGKdaEGVFSVVPWSPDLAKKKPGAKEVNERYKKkYGEDMTGHAARAYTAAWVLADALERAGSTDPeairAAAALT 320
|
330 340 350
....*....|....*....|....*....|..
gi 15600106 334 LKSHPVQTVMGKK-EWDKKGDLKVSDYVVYEW 364
Cdd:cd06340 321 LDIPEGLIMPGGGvKFDEKGQNVLARPVVVQW 352
|
|
| PBP1_ABC_HAAT-like |
cd19981 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-315 |
2.21e-59 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380636 [Multi-domain] Cd Length: 297 Bit Score: 194.05 E-value: 2.21e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd19981 2 IGFFAPLTGPAAADGKSALHGAELAVEQINAAGGINGKKVELVVYDDQASPKQAVNIAQKLIEQDKVVAVVSGSYSGPTR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGlSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd19981 82 AAAPIFQEAKVPMVSAYAVHPDITKAG-DYVFRVAFLGPVQGRAGAEYAVKDLGAKKVAILTIDNDFGKSLAAGFKEEAK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 191 KLGVkEVLYE-GLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGgpQY 269
Cdd:cd19981 161 KLGA-EIVSEyAYALGDRDFRPILTKIKSANPDAIYASGYYAEAAPIVKQARELGIKVPIIGQEGYDSPKFIEIAG--SA 237
|
250 260 270 280
....*....|....*....|....*....|....*....|....*....
gi 15600106 270 VKGVLMT--FGADPRLiPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSL 315
Cdd:cd19981 238 AEGVIITtsLNRDSDR-PITQKFIKEYRKRyGIDPDMVAASTYDAVMVL 285
|
|
| PBP1_ABC_HAAT-like |
cd19986 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-312 |
8.90e-59 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380641 [Multi-domain] Cd Length: 297 Bit Score: 192.46 E-value: 8.90e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd19986 2 IGVVAPLTGPAALNGEYQKNGAQLALEEINAAGGVLGRPLELVVEDDQGTNTGAVNAVNKLISDDKVVAVIGPHYSTQVL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITpGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd19986 82 AVSPLVKEAKIPVIT-GGTSPKLTEQGNPYMFRIRPSDSVSAKALAKYAVEELGAKKIAILYDNDDFGTGGADVVTAALK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 191 KLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGgpQYV 270
Cdd:cd19986 161 ALGLEPVAVESYNTGDKDFTAQLLKLKNSGADVIIAWGHDAEAALIARQIRQLGLDVPVIGSSSFATPTVLLLAG--EAL 238
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 15600106 271 KGVL-MTFGADPRLIPDGKAVVEKFRAG-GFEPEGYTLYSYASI 312
Cdd:cd19986 239 EGIYsVTDFVPSDPDPKVQAFVKKYKAKyGEDPDLYSAWYYDAM 282
|
|
| Peripla_BP_6 |
pfam13458 |
Periplasmic binding protein; This family includes a diverse range of periplasmic binding ... |
29-369 |
7.69e-58 |
|
Periplasmic binding protein; This family includes a diverse range of periplasmic binding proteins.
Pssm-ID: 433225 [Multi-domain] Cd Length: 342 Bit Score: 191.33 E-value: 7.69e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 29 VVIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSS 108
Cdd:pfam13458 2 IKIGVLTPLSGPYASSGKSSRAGARAAIEEINAAGGVNGRKIELVVADDQGDPDVAAAAARRLVDQDGVDAIVGGVSSAV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 109 TIPASEVYDEAGIIAITPGSTNPqvtERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQ 188
Cdd:pfam13458 82 ALAVAEVLAKKGVPVIGPAALTG---EKCSPYVFSLGPTYSAQATALGRYLAKELGGKKVALIGADYAFGRALAAAAKAA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 189 LNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGPQ 268
Cdd:pfam13458 159 AKAAGGEVVGEVRYPLGTTDFSSQVLQIKASGADAVLLANAGADTVNLLKQAREAGLDAKGIKLVGLGGDEPDLKALGGD 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 269 YVKGVLMT--FGADPRLiPDGKAVVEKF--RAGGFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWLKSHPVQTVMG 344
Cdd:pfam13458 239 AAEGVYATvpFFPDLDN-PATRAFVAAFaaKYGEAPPTQFAAGGYIAADLLLAALEAAGSPTREAVIAALRALPYDGPFG 317
|
330 340
....*....|....*....|....*
gi 15600106 345 KKEWDKKGDLKVSDYVVYEWDDKGK 369
Cdd:pfam13458 318 PVGFRAEDHQAVHCMYLVQVKADGK 342
|
|
| PBP1_ABC_ligand_binding-like |
cd06335 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-296 |
6.14e-56 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380558 [Multi-domain] Cd Length: 348 Bit Score: 186.66 E-value: 6.14e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd06335 1 KIGVIGPLTGPSAELGESARRGVELAVEEINAAGGILGRKIELVERDDEANPTKAVQNAQELIDKEKVVAIIGPTNSGVA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVT---ERGLSGMFRMCGRDDQQGVVAGDYIVNVlKAKKVAVIHDKDTYGQGLADATR 186
Cdd:cd06335 81 LATIPILQEAKIPLIIPVATGTAITkppAKPRNYIFRVAASDTLQADFLVDYAVKK-GFKKIAILHDTTGYGQGGLKDVE 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 187 AQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGG 266
Cdd:cd06335 160 AALKKRGITPVATESFKIGDTDMTPQLLKAKDAGADVILVYGLGPDLAQILKAMEKLGWKVPLVGSWGLSMPNFIELAGP 239
|
250 260 270
....*....|....*....|....*....|..
gi 15600106 267 pqYVKGVLM--TFGADPRLiPDGKAVVEKFRA 296
Cdd:cd06335 240 --LAEGTIMtqTFIEDYLT-PRAKKFIDAYKK 268
|
|
| PBP1_ABC_ligand_binding-like |
cd06343 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
29-311 |
2.84e-54 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however its ligand specificity has not been determined experimentally.
Pssm-ID: 380566 [Multi-domain] Cd Length: 355 Bit Score: 182.38 E-value: 2.84e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 29 VVIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSS 108
Cdd:cd06343 7 IKIGTSLPLSGPAAAYGKPVRAGAAAYFDEVNAAGGINGRKIELIVEDDGYDPARAVAAVRKLVEQDKVFAIVGGLGTPT 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 109 TIPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQ 188
Cdd:cd06343 87 NLAVRPYLNEAGVPQLFPATGASALSPPPKPYTFGVQPSYEDEGRILADYIVETLPAAKVAVLYQNDDFGKDGLEGLKEA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 189 LNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSdDGVVTDELATTAGGPQ 268
Cdd:cd06343 167 LKAYGLEVVAEETYEPGDTDFSSQVLKLKAAGADVVVLGTLPKEAAAALKEAAKLGWKPTFLG-SSVSADPTTLAKAGGD 245
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 15600106 269 YVKGVLMT-FGADPRliPDGKAVVEKFRA------GGFEPEGYTLYSYAS 311
Cdd:cd06343 246 AAEGVYSAsYLKDPT--DADDPAVKEFREaykkyfPDDPPNAYALYGYAA 293
|
|
| PBP1_ABC_ligand_binding-like |
cd06338 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-364 |
4.52e-54 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380561 [Multi-domain] Cd Length: 347 Bit Score: 181.63 E-value: 4.52e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGE----KIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFC 105
Cdd:cd06338 1 KIGASLSLTGPFAGEGKAQKRGYELWVEDVNAAGGVKGGgkkrPVELVYYDDQSDPATAVRLYEKLITEDKVDLLLGPYS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 106 SSSTIPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIV-NVLKAKKVAVIHDKDTYGQGLADA 184
Cdd:cd06338 81 SGLTLAAAPVAEKYGIPMIAGGAASDSIFERGYKYVFGVLPPASDYAKGLLDLLAeLGPKPKTVAIVYEDDPFGKEVAEG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 185 TRAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMS-----DDGVVTDE 259
Cdd:cd06338 161 AREAAKKAGLEVVYDESYPPGTTDFSPLLTKVKAANPDILLVGGYPPDAITLVRQMKELGYNPKAFFltvgpAFPAFREA 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 260 LATTA----GGPQYVKGVLMTFGadprliPDGKAVVEKFRA-GGFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWL 334
Cdd:cd06338 241 LGKDAegvlGPSQWEPSLPYKVF------PGAKEFVKAYKEkFGEEPSYHAAAAYAAGQVLQQAIEKAGSLDPEKVRDAL 314
|
330 340 350
....*....|....*....|....*....|
gi 15600106 335 KSHPVQTVMGKKEWDKKGDLKVSDYVVYEW 364
Cdd:cd06338 315 ASLDFDTVYGPIKFDETGLQIGKPMVVVQW 344
|
|
| PBP1_ABC_HAAT-like |
cd19985 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-255 |
6.68e-52 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380640 [Multi-domain] Cd Length: 321 Bit Score: 175.54 E-value: 6.68e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVAnRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd19985 2 IAVVGPMSGKSASKGKSMLRGAELYIDQINAAGGINGKKVKLDVFDDQNDPDAARKAA-QIIVSDKALAVIGHYYSSASI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGlSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd19985 81 AAGKIYKKAGIPAITPSATADAVTRDN-PWYFRVIFNDSLQGRFLANYAKKVLKKDKVSIIYEEDSYGKSLASVFEATAR 159
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15600106 191 KLGVKEVLYEGLTRGEKDFNALVTKIRA------SGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGV 255
Cdd:cd19985 160 ALGLKVLKKWSFDTDSSQLDQNLDQIVDelkkapDEPGVIFLATHADEGAKLIKKLRDAGLKAPIIGPDSL 230
|
|
| PBP1_ABC_RPA1789-like |
cd06333 |
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, ... |
30-296 |
1.56e-51 |
|
type 1 periplasmic binding-protein component (CouP) of an ABC system (CouPSTU; RPA1789, RPA1791-1793), involved in active transport of lignin-derived aromatic substrates, and its close homologs; This group includes RPA1789 (CouP) from Rhodopseudomonas palustris and its close homologs in other bacteria. RPA1789 (CouP) is the periplasmic binding-protein component of an ABC system (CouPSTU; RPA1789, RPA1791-1793) that is involved in the active transport of lignin-derived aromatic substrates. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380556 [Multi-domain] Cd Length: 342 Bit Score: 175.04 E-value: 1.56e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd06333 1 KIGAILSLTGPAASLGIPERNAVELLVEQINAAGGINGRKLELIVYDDESDPTKAVTNARKLIEEDKVDAIIGPSTTGES 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVTERGlSGMFRMCGRDDQQGVVAGDYIVNVlKAKKVAVIHDKDTYGQGLADATRAQL 189
Cdd:cd06333 81 LAVAPIAEEAKVPLISLAGAAAIVEPVR-KWVFKTPQSDSLVAEAILDYMKKK-GIKKVALLGDSDAYGQSGRAALKKLA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGPqy 269
Cdd:cd06333 159 PEYGIEIVADERFARTDTDMTAQLTKIRAAKPDAVLVWASGPPAALVAKNLRQLGYKGPIYQSHGAANQDFIKLAGKA-- 236
|
250 260 270
....*....|....*....|....*....|..
gi 15600106 270 VKGVLMTFGA--DPRLIPDG---KAVVEKFRA 296
Cdd:cd06333 237 AEGVILPAGKllVADQLPDSdpqKKVLLEFVK 268
|
|
| PBP1_ABC_ligand_binding-like |
cd06345 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
30-353 |
1.02e-48 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380568 [Multi-domain] Cd Length: 356 Bit Score: 168.21 E-value: 1.02e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTganASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd06345 1 KIGVLGPLS---APAGEAMERGAELAVEEINAAGGILGRKVELVVADTQGKPEDGVAAAERLITEDKVDAIVGGFRSEVV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVTER------GLSGMFRMCGRDDQQGVVAGDYI----VNVLKAKKVAVIHDKDTYGQ 179
Cdd:cd06345 78 LAAMEVAAEYKVPFIVTGAASPAITKKvkkdyeKYKYVFRVGPNNSYLGATVAEFLkdllVEKLGFKKVAILAEDAAWGR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 180 GLADATRAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDE 259
Cdd:cd06345 158 GIAEALKKLLPEAGLEVVGVERFPTGTTDFTPILSKIKASGADVIVTIFSGPGGILLVKQWAELGVPAPLVGINVPAQDP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 260 LA--TTAGGPQYVkgVLMTFGAD-PRLIPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWLK 335
Cdd:cd06345 238 EFweNTGGAGEYE--ITLAFAAPkAKVTPKTKPFVDAYKKKyGEAPNYTAYTAYDAIYILAEAIERAGSTDPDALVKALE 315
|
330
....*....|....*...
gi 15600106 336 SHPVQTVMGKKEWDKKGD 353
Cdd:cd06345 316 KTDYEGVRGRIKFDKKDE 333
|
|
| PBP1_ABC_ligand_binding-like |
cd06336 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-349 |
2.15e-48 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380559 [Multi-domain] Cd Length: 345 Bit Score: 167.03 E-value: 2.15e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGI--NGE--KIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFC 105
Cdd:cd06336 1 KIGFLGPLSGPAAAWGLPMLRGLELAADEINAAGGIkvGGKkyKVEVVSYDDKYTPAEAVAAARRLVSQDGVKFIFGPGG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 106 SSSTIPASEVYDEAGIIAITPGSTNPqVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADAT 185
Cdd:cd06336 81 SAIAAAVQPVTERNKVLLLTAAFSDP-ILGPDNPLLFRIPPTPYEYAPPFIKWLKKNGPIKTVALIAPNDATGKDWAAAF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 186 RAQLNKLGVKEV---LYEgltRGEKDFNALVTKIRASGAEVVYFGGLHP-EAGPLVRQMREQGLTARFMSDDGVVTDELA 261
Cdd:cd06336 160 VAAWKAAGGEVVaeeFYD---RGTTDFYPVLTKILALKPDALDLGGSSPgPAGLIIKQARELGFKGPFVSEGGAKADEIL 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 262 tTAGGPQYVKGVLMTFGADPRLI--PDGKAVVEKFRAG-GFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWL--KS 336
Cdd:cd06336 237 -KEVGGEAAEGFIGVLPADDDPIasPGAKAFVERYKKKyGEPPNSESALFYDAAYILVKAMEKAGTVDDTKKIRAAlaML 315
|
330
....*....|...
gi 15600106 337 HPVQTVMGKKEWD 349
Cdd:cd06336 316 SPDETLFGKLKWG 328
|
|
| PBP1_ABC_HAAT-like |
cd06348 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-361 |
4.03e-46 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380571 [Multi-domain] Cd Length: 342 Bit Score: 160.86 E-value: 4.03e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd06348 2 IGVALSLTGPGALYGQSQKNGAQLAVEEINAAGGVGGVKIELIVEDTAGDPEQAINAFQKLINQDKVLAILGPTLSSEAF 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGlSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHD-KDTYGQGLADATRAQL 189
Cdd:cd06348 82 AADPIAQQAKVPVVGISNTAPGITDIG-PYIFRNSLPEDKVIPPTVKAAKKKYGIKKVAVLYDqDDAFTVSGTKVFPAAL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGgpQY 269
Cdd:cd06348 161 KKNGVEVLDTETFQTGDTDFSAQLTKIKALNPDAIVISALAQEGALIVKQARELGLKGPIVGGNGFNSPDLIKLAG--KA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 270 VKGVLMTFGADP-RLIPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSLAAA-FNGAGANDPAKAAEWLK----SHPVQTV 342
Cdd:cd06348 239 AEGVIVGSAWSPdNPDPKNQAFVAAYKEKyGKEPDQFAAQAYDAAYILAEAiKKAGSTTDRADLRDALAriliAKDFEGP 318
|
330
....*....|....*....
gi 15600106 343 MGKKEWDKKGDLKVSDYVV 361
Cdd:cd06348 319 LGPFSFDADRDGIQPPVVL 337
|
|
| PBP1_ABC_ligand_binding-like |
cd19982 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-313 |
9.43e-46 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, their ligand specificity has not been determined experimentally.
Pssm-ID: 380637 [Multi-domain] Cd Length: 302 Bit Score: 158.60 E-value: 9.43e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd19982 2 IGAILSLTGPFAPFGEMFKNGYEMALEEINAAGGIKGKKLELVIEDDQSKPQTALAAAEKLVSQDKVPLIVGGYSSGITL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd19982 82 PVAAVAERQKIPLLVPTAADDDITKPGYKYVFRLNPPASIYAKALFDFFKELVKPKTIAILYENTAFGTSVAKAARRFAK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 191 KLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFmsddgvvtdeLATTAGG---P 267
Cdd:cd19982 162 KRGIEVVADESYDKGATDFKPLLNKVKAANPDVVYMVSYLNDAILLMRQAKELGLNPKL----------FAGGGAGftiP 231
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 15600106 268 QYVKGV------LMTFGA---DPRLiPDGKAVVEKFRA-GGFEPEGYTLYSYASIQ 313
Cdd:cd19982 232 EFLKQAgplaeyVVTATLwspDVKY-PGAKEFYEKYKAkYGVEPSYHEAEAYAALY 286
|
|
| PBP1_As_SBP-like |
cd06330 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
31-352 |
4.77e-41 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.
Pssm-ID: 380553 [Multi-domain] Cd Length: 342 Bit Score: 147.32 E-value: 4.77e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd06330 2 IGVITPLSGAAAVYGEPARNGAELAVEEINAAGGILGRKIELVVRDDKGKPDEAVRAARELVLQEGVDFLIGTISSGVAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGLSG-MFRMCGRDDQQGVVAGDYIV-NVLKAKKVAVIHDKDTYGQGLADATRAQ 188
Cdd:cd06330 82 AVAPVAEELKVLFIATDAATDRLTEENFNPyVFRTSPNTYMDAVAAALYAAkKPPDVKRWAGIGPDYEYGRDSWAAFKAA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 189 LNKLGVK-EVLYEGLTR-GEKDFNALVTKIRASGAEVVY---FGGlhpEAGPLVRQMREQGLTAR--FMSDDGVVTDELa 261
Cdd:cd06330 162 LKKLKPDvEVVGELWPKlGATDYTAYITALLAAKPDGVFsslWGG---DLVTFVKQAKPYGLFDKtkVVSGLGGGSEVL- 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 262 tTAGGPQYVKGVLMT----FGADPrlIPDGKAVVEKFRA-GGFEPEGYTLYSYASIQSLAAAFNGAGANDPAKAAEWLKS 336
Cdd:cd06330 238 -QALGKEMPEGLIGGgrypFGWPD--TPLNKAFVEAYRAkYGEYPTYWAYEAYAAVMALKAAIEKAGSTDTDKVIAALEG 314
|
330
....*....|....*.
gi 15600106 337 HPVQTVMGKKEWDKKG 352
Cdd:cd06330 315 LTFDTPGGKITIRAED 330
|
|
| PBP1_ABC_transporter_GPCR_C-like |
cd04509 |
Family C of G-protein coupled receptors and their close homologs, the type 1 ... |
42-255 |
1.03e-36 |
|
Family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems; This CD includes members of the family C of G-protein coupled receptors and their close homologs, the type 1 periplasmic-binding proteins of ATP-binding cassette transporter-like systems. The family C GPCR includes glutamate/glycine-gated ion channels such as the NMDA receptor, G-protein-coupled receptors, metabotropic glutamate, GABA-B, calcium sensing, pheromone receptors, and atrial natriuretic peptide-guanylate cyclase receptors. The glutamate receptors that form cation-selective ion channels, iGluR, can be classified into three different subgroups according to their binding-affinity for the agonists NMDA (N-methyl-D-asparate), AMPA (alpha-amino-3-dihydro-5-methyl-3-oxo-4-isoxazolepropionic acid), and kainate. L-glutamate is a major neurotransmitter in the brain of vertebrates and acts through either mGluRs or iGluRs. mGluRs subunits possess seven transmembrane segments and a large N-terminal extracellular domain. ABC-type leucine-isoleucine-valine binding protein (LIVBP) is a bacterial periplasmic binding protein that has homology with the amino-terminal domain of the glutamate-receptor ion channels (iGluRs). The extracellular regions of iGluRs are made of two PBP-like domains in tandem, a LIVBP-like domain that constitutes the N terminus (included in this model) followed by a domain related to lysine-arginine-ornithine-binding protein (LAOBP) that belongs to the type 2 periplasmic binding fold protein superfamily. The uncharacterized periplasmic components of various ABC-type transport systems are also included in this family.
Pssm-ID: 380490 Cd Length: 306 Bit Score: 135.13 E-value: 1.03e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 42 ASFGEQYWRGASQAAEDINAAG-GINGEKIKLVKADDACEPKQAVAVANRLVD----------------------QDKAI 98
Cdd:cd04509 23 AQYGIQRFEAMEQALDDINADPnLLPNNTLGIVIYDDCCDPKQALEQSNKFVNdliqkdtsdvrctngeppvfvkPEGIK 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 99 AVVGHFCSSSTIPASEVYDEAGIIAITPGSTNPQVT-ERGLSGMFRMCGRDDQQGVVAGDYIVNvLKAKKVAVIHDKDTY 177
Cdd:cd04509 103 GVIGHLCSSVTIPVSNILELFGIPQITYAATAPELSdDRGYQLFLRVVPLDSDQAPAMADIVKE-KVWQYVSIVHDEGQY 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 178 GQGLADATRAQLNKLGVKEVLYEGLT--RGEKDFNALVTKIRAS-GAEVVYFGGLHPEAGPLVRQMREQGLTARF--MSD 252
Cdd:cd04509 182 GEGGARAFQDGLKKGGLCIAFSDGITagEKTKDFDRLVARLKKEnNIRFVVYFGYHPEMGQILRAARRAGLVGKFqfMGS 261
|
...
gi 15600106 253 DGV 255
Cdd:cd04509 262 DGW 264
|
|
| PBP1_ABC_HAAT-like |
cd19983 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type ... |
31-315 |
1.13e-35 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems predicted to be involved in uptake of hydrophobic amino acids or peptides; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in the uptake of hydrophobic amino acids or peptides. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); however, its ligand specificity has not been determined experimentally.
Pssm-ID: 380638 [Multi-domain] Cd Length: 303 Bit Score: 131.94 E-value: 1.13e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQdKAIAVVGHFCSSSTI 110
Cdd:cd19983 2 IGFVGGLTGRYSDLGVQGRNGAQLAVEEINAAGGINGRPVELIIRDDQQDPEAAKAADRELIAG-GVVAIIGHMTSAMTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQvtergLSG----MFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKD--TYGQGLADA 184
Cdd:cd19983 81 AVLPVINEAKVLMISPTVSTPE-----LSGkddyFFRVTPTTRESAQALARYAYNRGGLRRVAVIYDLSnrAYSESWLDN 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 185 TRAQLNKLG---VKEVLYEglTRGEKDFNALVTKIRASGAEVVYF--GGLHpeAGPLVRQMREQGLTARFMSDDGVVTDE 259
Cdd:cd19983 156 FRSEFEALGgriVAEIPFS--SGADVDFSDLARRLLASKPDGLLLvaSAVD--TAMLAQQIRKLGSKIPLFSSAWAATEE 231
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 15600106 260 LATTAGgpQYVKGVLMTFGAD-----PRLIPDGKAVVEKFragGFEPEGYTLYSYASIQSL 315
Cdd:cd19983 232 LLELGG--KAVEGMLFSQAYDrnssnPRYLAFKEAYEERF---GREPSFAAAYAYEAAMVL 287
|
|
| PBP1_ABC_ligand_binding-like |
cd19978 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
29-276 |
2.38e-33 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380633 [Multi-domain] Cd Length: 341 Bit Score: 126.92 E-value: 2.38e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 29 VVIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSS 108
Cdd:cd19978 1 IRLGMSAALSGPAAELGNEMKRGIEAAFNEVNAQGGVNGRKIKLIALDDGYEPDRTVKNTKKLIEEDKVFALIGYVGTPT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 109 TIPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQ 188
Cdd:cd19978 81 ALAALPLANEKKIPLFGPFTGAEFLRTPFLPYVFNLRASYADETEALVDYLVKTLGPKRIAIFYQNDAFGLAGLEGAKKA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 189 LNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGpq 268
Cdd:cd19978 161 LKKRGLTPVAEGSYTRNTLDVEEALAKILKAKPEAIILVGTYAPAAEFIRLARAAGLNPLFANVSFVGSEALALELGD-- 238
|
....*...
gi 15600106 269 YVKGVLMT 276
Cdd:cd19978 239 YGEGVIVS 246
|
|
| PBP1_ABC_ligand_binding-like |
cd06326 |
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to ... |
29-276 |
2.76e-33 |
|
periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions; This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.
Pssm-ID: 380549 [Multi-domain] Cd Length: 339 Bit Score: 126.50 E-value: 2.76e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 29 VVIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSS 108
Cdd:cd06326 1 IVIGQSAPLSGPLAELGREYLAGAKAYFDQVNAAGGINGRKIRLVTLDDGYDPARTVENTRQLIEQDKVVALFGYVGTAN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 109 TIPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCGRDDQQgvvaGDYIVNVLKA---KKVAVIHDKDTYGQGLADAT 185
Cdd:cd06326 81 VEAVLPLLEEAGVPLVGPLTGADSLREPGNPYVFHVRASYADE----VEKIVRHLATlglKRIAVVYQDDPFGKEGLAAA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 186 RAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARF--MSddgVVTDELATT 263
Cdd:cd06326 157 EAALAARGLEPVATAAVARNAADVAAAAAALAAAKPQAVVLIAAGKAAAAFIKALRAAGGAAQFygLS---VVGAAALAK 233
|
250
....*....|...
gi 15600106 264 AGGPQyVKGVLMT 276
Cdd:cd06326 234 ALGDA-ARGVVVS 245
|
|
| PBP1_AmiC-like |
cd06331 |
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system ... |
31-296 |
3.78e-32 |
|
type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF); This group includes the type 1 periplasmic components of amide-binding protein (AmiC) and the active transport system for short-chain and urea (FmdDEF), found in bacteria and Archaea. AmiC controls expression of the amidase operon by a ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon is induced. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380554 [Multi-domain] Cd Length: 333 Bit Score: 123.48 E-value: 3.78e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd06331 2 IGLLTPLSGPASVYGRAIANGAELAVEEINAAGGVLGRPVELVVEDDASDPATAVAAARRLIQQDKVDAIVGPITSATRN 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERglsGMFRMCGRDDQQGVVAGDYIVNvLKAKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd06331 82 AVAPVAERAKVPLLYPTFYEGGECSP---YLFCFGEVPNQQLDPLIPWLME-EYGKKFYLIGSDYVWPRTMNDAARRVIE 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 191 KLGvKEVLYEGLTR-GEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARfMSDDGVVTDELATTAGGPQY 269
Cdd:cd06331 158 AHG-GEVVGEEYLPlGTTDFSSVIEKIKASGADVVLSTLVGADAVTFLKQFAAAGLRRK-VRIAALLFDENTLAGLGAEA 235
|
250 260 270
....*....|....*....|....*....|
gi 15600106 270 VKGVLMT---FGADPRliPDGKAVVEKFRA 296
Cdd:cd06331 236 AEGIYSVlsyFQSLDT--PENKAFVAAYRK 263
|
|
| PBP1_SBP-like |
cd19989 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
31-315 |
1.63e-31 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380644 [Multi-domain] Cd Length: 299 Bit Score: 120.84 E-value: 1.63e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd19989 2 IGVLTPLSGPYAALGEEARRGAQLAVEEINAAGGILGRPVELVVEDTEGKPATAVQKARKLVEQDGVDFLTGAVSSAVAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGS-TNPQVTERGLSGMFRMCGRDDQQGVVAGDYIVNvLKAKKVAVIHDKDTYGQGLADATRAQL 189
Cdd:cd19989 82 AVAPKAAELKVPYLVTVAaDDELTGENCNRYTFRVNTSDRMIARALAPWLAE-NGGKKWYIVYADYAWGQSSAEAFKEAI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLGvKEVLYEGLTR-GEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGPQ 268
Cdd:cd19989 161 EELG-GEVVGTLFAPlGTTDFSSYITQISDSGADGLLLALAGSDAVNFLKQAGQFGLGKKYKIVGGILSIEPLALPALGD 239
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 15600106 269 YVKGVLMT----FGADPrliPDGKAVVEKFRAGGFEPEGYTLY-SYASIQSL 315
Cdd:cd19989 240 AAEGVYGGvrypPTLDT---PANRAFVEAYEKEYGEAPDNFAGeAYEAMQAL 288
|
|
| PBP1_ABC_ligand_binding-like |
cd06341 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-315 |
2.55e-26 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380564 [Multi-domain] Cd Length: 340 Bit Score: 107.39 E-value: 2.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANA-SFGEQywRGASQAAED-INAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFcSS 107
Cdd:cd06341 1 KIGLIYPDTGPGAaSFSAA--RAGAEARFGlANAAGGINGRKVEYVWCDDQSDPATNLQAARQLVEDEKVFALVGSS-SA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 108 STIPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRmcGRDDQQGVVAGDYIVNvLKAKKVAVI-HDKDTYGQGLADATR 186
Cdd:cd06341 78 ASGSANDYLAQAGIPVVGGAGVSVWCFRNMFSNFFS--LGGGGSTTTYGQYAAA-LGGTKAAVVvTDIPAASQQLAQQLA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 187 AQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGg 266
Cdd:cd06341 155 ASLRAAGVEVVGTAPYAAAAPDYTAVAQAAKAAGADAVVGVLDPDVAARVLKAARAQGLDLKVALSPSGYDPSVLAAYG- 233
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 15600106 267 pQYVKGVLMTFGADPRL--IPDGK---AVVEKFRAGGFEPE-GYTLYSYASIQSL 315
Cdd:cd06341 234 -AALAGVSVASTFLPFEadTPAVKayrAAMAKYAPELQDPLqQFALSGYIAADLF 287
|
|
| PBP1_SBP-like |
cd19987 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
30-348 |
2.41e-25 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380642 [Multi-domain] Cd Length: 353 Bit Score: 105.10 E-value: 2.41e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAG------------GINGEKIKLVKADDACEPKQAVAVANRLVDQDKA 97
Cdd:cd19987 1 TIGLNVPLSGPYAPQGEDQRRGFELAVDHLNNGGglvdkdsrlsgdGILGKKVELVTADTETKADTAVDNAKRLIEQDGA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 98 IAVVGHFCSSSTIPASEVYDEAGIIAITPGSTNPQVT-ERGLSGMFRMCGRDDQQGVVAGDYIVNVL-KAKKVAVIHDKD 175
Cdd:cd19987 81 VMITGGSSSAVAVAAQKLAQKEGVLYFAGLSHSNDTTgKDCHRYGFRECFNAHMSAKALAPYLVEKFgKDRKYFYLTADY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 176 TYGQGLADATRAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFmsdDGV 255
Cdd:cd19987 161 TWGHSTEQSMREYTEAHGWKTVGNPATPLGETDFSAALLNAADSGADVLVLVLFGRDMVNALKQAKQFGLLKKM---DIV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 256 VTDELATTA--GGPQYVKGVLMTFGADPRL---IPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSLAAAFNGAGANDPAK 329
Cdd:cd19987 238 VPLLTAFMAesVGPEIMEGVLGTVNWHWSLpddYSYAFGKAEAFEKEyGAYPSQAAASAYVQVLQYAAAVERAGSFDPPA 317
|
330
....*....|....*....
gi 15600106 330 AAEWLKSHPVQTVMGKKEW 348
Cdd:cd19987 318 VIRALEGHEYTLLKGEQYW 336
|
|
| PBP1_aromatic_compounds-like |
cd06332 |
type 1 periplasmic binding proteins of active transport systems predicted to be involved in ... |
31-363 |
2.65e-25 |
|
type 1 periplasmic binding proteins of active transport systems predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; This group includes the type 1 periplasmic binding proteins of active transport systems that are predicted to be involved in transport of aromatic compounds such as 2-nitrobenzoic acid and alkylbenzenes; their substrate specificities are not well characterized, however. Members also exhibit close similarity to active transport systems for short chain amides and/or urea found in bacteria and archaea.
Pssm-ID: 380555 [Multi-domain] Cd Length: 336 Bit Score: 104.60 E-value: 2.65e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINaaGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd06332 2 IGLLAPLTGPFAALGEDMVRGFELALEEVG--GEVAGRKVELVVEDDAGDPDTAVTKARKLVEQDKVDVLIGPLSGDEGL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGLSG-MFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQL 189
Cdd:cd06332 80 AVAPYAKEPGVPFINPVAGADDLTQRAKAPnFFRTSFTGSQWSAPLGDYAYKELGYKKVATIGSDYAFGYEQAAGFKRGF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLG---VKEVLYEGltrGEKDFNALVTKIRASgAEVVYFGGLHPEAGPLVRQMREQGLTAR-FMSDDGVVTDELATTAG 265
Cdd:cd06332 160 EAAGgevVQEIWVPL---GTTDFSPYIAQIPSA-DDAVFAFLGGADAVRFLKQYREFGLKDKiPLIGGGTTVDESVLPAM 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 266 GPQYVKGVLMTFGADPRLIPDGKAVVEKFRA-GGFEPEGYTLYSYASIQSLAA--AFNGAGANDPAKAAEWLKSHPVQTV 342
Cdd:cd06332 236 GDAALGIISASHYAEGLDNPENKKFVAAYKKkFGKLPSLYAAGGYDGAQAILEalEAVGGDVSDKQALAAALRKVKFDSP 315
|
330 340
....*....|....*....|.
gi 15600106 343 MGKKEWDKKGDLkVSDYVVYE 363
Cdd:cd06332 316 RGPFSFDENRNP-VQNVYIRE 335
|
|
| PBP1_SBP-like |
cd06329 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
31-331 |
1.04e-23 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380552 [Multi-domain] Cd Length: 343 Bit Score: 100.43 E-value: 1.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDkaIAVVGHFCSSST- 109
Cdd:cd06329 2 IAFIDPLSGPFASVGEIYLKGLQFAIEEINAGGGLLGRKIELVPFDNKGSPQEALIQLKKAIDQG--IRFVLQGNSSAVa 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 ---IPASEVYDEAG----IIAITPGSTNPQVTERGLS-GMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGL 181
Cdd:cd06329 80 galIDAIEKHNQRNpdkrVLFLNYGAEAPELTGAKCSfWHFRFDANADMKMAALADYMKKDGSIKKVYLINQDYSFGRDV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 182 ADATRAQLNKLG-----VKEVLYEgLTRgEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARF----MSD 252
Cdd:cd06329 160 AAAAKKNLKKKRpdieiVGEDLHP-LGK-VKDFSPYIAKIKASGADTVITGNWGNDLTLLMKAARDSGLKAPFytyyADG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 253 DGVvtdelaTTAGGPQYVKGVLM-TFGADPRLIPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSLAAAFNGAGANDPAKA 330
Cdd:cd06329 238 PGA------PAAIGEAGVGRLVAvAYWHPNPKTPELEKFAEAFRAKyGRYPDFNIGRTYMGVEMLAAAIKKAGSTDPEKV 311
|
.
gi 15600106 331 A 331
Cdd:cd06329 312 A 312
|
|
| PBP1_ABC_ligand_binding-like |
cd19979 |
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes ... |
38-244 |
2.38e-19 |
|
amino acid amide ABC transporter substrate binding protein haat family; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380634 [Multi-domain] Cd Length: 350 Bit Score: 88.05 E-value: 2.38e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 38 TGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVG--HfcsssTIPASEV 115
Cdd:cd19979 9 SGGSAASGEAIKRGIQLAIDEINAAGGLLGRKLELVAKDHRGNPARGVDNLREFAADPDVLAVFGglH-----SPVLLAE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 116 YD---EAGIIAITPGSTNPQVTERGLSG--MFRMCGRDDQqgvvAGDYIVN-VLKA--KKVAVIHDKDTYGQGLADATRA 187
Cdd:cd19979 84 LDfihELKIPYLVPWAAATPITRNGYSPnyIFRLSVDDSL----AGPFLVEyALKKgcKRPALLLENTGWGRSNLKAMTK 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 15600106 188 QLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQG 244
Cdd:cd19979 160 ALAKKGLQPVGVEWFNWGDTDAKPQLRALKAAGADAILLVANAPEGAAIVKALAALP 216
|
|
| PBP1_RPA0668_benzoate-like |
cd20014 |
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the ... |
31-309 |
3.73e-19 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0668), involved in in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0668 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0668 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380667 [Multi-domain] Cd Length: 346 Bit Score: 87.29 E-value: 3.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINaaGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd20014 2 IGLLLPYSGVYAALGEDIRNGFQLYLDEHG--GKLGGRPIELVKEDDEADPDVALQKARKLIEQDKVDVLVGPVSSGVAL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVT-ERGLSGMFRMCGRDDQQGVVAGDYIVNVLKaKKVAVIHDKDTYGQGLADATRAQL 189
Cdd:cd20014 80 AIRDVVEQAKVPLIVANAGANALTrAACSPYIFRTSFSNWQLGYALGKYAAENVG-KTVVTIASDYAAGREVVAGFKEGF 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 NKLGvKEVLYEGLTR--GEKDFNALVTKIRASGAEVVY--FGGlhPEAGPLVRQMREQGLTARF-MSDDGVVTDELATTA 264
Cdd:cd20014 159 EAAG-GKVVGEIWTPlgTTTDFSPYLTQIAASGPDAVYafFAG--ADAVRFVKQYAEFGLKGKIpLYGPGFLTDEDVLPA 235
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 15600106 265 GGPQyVKGVLMTFGADPRL-IPDGKAVVEKFRAG-GFEPEGYTLYSY 309
Cdd:cd20014 236 LGEA-AEGIITVLHYAPTLdNPANRAFVAAYQAKyGRLPDVYAVQGY 281
|
|
| PBP1_ABC_ligand_binding-like |
cd06334 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
30-304 |
5.04e-19 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380557 [Multi-domain] Cd Length: 360 Bit Score: 87.30 E-value: 5.04e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHfcssST 109
Cdd:cd06334 1 KIGLLTDLTGPTADVGKPYAQGVRDYLNYVNEEGGINGVKIELEECDTGYKVPRAVACYKRLKAQDGVVAILGW----GT 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPA---SEVYDEAGIIAITPGS---------TNPQVterglsgmFRMCGRDDQQGVVAGDYIVN----VLKAKKVAVIHD 173
Cdd:cd06334 77 GDTealAPRVAKDKIPYISASYgrsladdgkVFPYN--------FFVGATYSSQARALLKYIAQewggKLKGPKVAFVYH 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 174 KDTYGQGLADATRAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDD 253
Cdd:cd06334 149 DSPFGREPIPALKAYAKELGFEVVAEQVPSPGALDATAQWLRIRRAGPDYVIIQGTGGSVAVIIKDAKRLGLKTKFIGNI 228
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....
gi 15600106 254 GVVTDELATTAGGPqyVKGVL-MTFGADPRLIPDGKAVVEKFRA--GGFEPEGY 304
Cdd:cd06334 229 WGGDEDLIKLAGDA--AEGYVgVSPFAFGTDDPPGKEIVEEVAKkgKGDGPEEV 280
|
|
| PBP1_alkylbenzenes-like |
cd06360 |
type 1 periplasmic binding component of active transport systems predicted be involved in ... |
31-374 |
4.56e-18 |
|
type 1 periplasmic binding component of active transport systems predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; This group includes the type 1 periplasmic binding component of active transport systems that are predicted be involved in anaerobic biodegradation of alkylbenzenes such as toluene and ethylbenzene; their substrate specificity is not well characterized, however.
Pssm-ID: 380583 [Multi-domain] Cd Length: 357 Bit Score: 84.27 E-value: 4.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDI-NAAGGingEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd06360 2 IGVLLPLTGPLAVNGEDVRDGFELYFDEIgNQVAG---RKIELIVEDDEGKPDVGLTKARKLVERDKVHVLAGIVSSAVA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVT-ERGLSGMFRMCGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADATRAQ 188
Cdd:cd06360 79 YAVRDYVVEQKIPLVISNAGAAPLTqELASPYIFRTSFSNGQYDAPFGQYAYEKLGYRRIAVMASDYAAGHEQAGAFART 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 189 LNKLGVKEV--LYEGLtrGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARF-MSDDGVVTDELATTAG 265
Cdd:cd06360 159 FKQAGGKVVqeIYPPL--GTADFAPYLARIQQDAADAVWAFFAGADAIRFVKQYDEYGLKGKLpLVGIGGLVDDAILPEQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 266 GPQYVkGVLMTFGADPRL-IPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSLAAAFNGAG--ANDPAKAAEWLKSHPVQT 341
Cdd:cd06360 237 GDAAL-GIVSYLHYSAALdTPENKAFVQAYRKKyGRDPGLYAEGGYVAARAIAEALEAVKgnVEDKEAFLEALRKVRFEA 315
|
330 340 350
....*....|....*....|....*....|...
gi 15600106 342 VMGKKEWDKKGDLKVSDYVVYEWDDKGKYHQLP 374
Cdd:cd06360 316 PRGPFRFDPYQQAVVTTYIRRVEKVDGKLVNVV 348
|
|
| ANF_receptor |
pfam01094 |
Receptor family ligand binding region; This family includes extracellular ligand binding ... |
55-249 |
7.37e-18 |
|
Receptor family ligand binding region; This family includes extracellular ligand binding domains of a wide range of receptors. This family also includes the bacterial amino acid binding proteins of known structure.
Pssm-ID: 460062 [Multi-domain] Cd Length: 347 Bit Score: 83.59 E-value: 7.37e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 55 AAEDINAAGGIN-GEKIKLVKADDACEPKQAVAVANRLVdQDKAIAVVGHFCSSSTIPASEVYDEAGIIAITPGSTNPQV 133
Cdd:pfam01094 9 AVEDINADPGLLpGTKLEYIILDTCCDPSLALAAALDLL-KGEVVAIIGPSCSSVASAVASLANEWKVPLISYGSTSPAL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 134 TERG-LSGMFRMCGRDDQQGVVAGDyIVNVLKAKKVAVIHDKDTYGQGLADATRAQLNKLGVKeVLYEGLTRGEKDFNAL 212
Cdd:pfam01094 88 SDLNrYPTFLRTTPSDTSQADAIVD-ILKHFGWKRVALIYSDDDYGESGLQALEDALRERGIR-VAYKAVIPPAQDDDEI 165
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 15600106 213 VTKIR---ASGAEVVYFGGLHPEAGPLVRQMREQGLTARF 249
Cdd:pfam01094 166 ARKLLkevKSRARVIVVCCSSETARRLLKAARELGMMGEG 205
|
|
| PBP1_SBP-like |
cd06328 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
30-245 |
1.57e-16 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative and gram-positive bacteria. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380551 [Multi-domain] Cd Length: 336 Bit Score: 79.65 E-value: 1.57e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEdiNAAGG---INGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCS 106
Cdd:cd06328 1 KIGVITSLTGPLAAYGKQTERGFELGLE--YATDGtmeVDGRKIEVIVKDDQGDPDTAKAAATELIGDDGVDILVGTVSS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 107 SSTIPASEVYDEAGIIAITPGSTNPQVTERGLS-GMFRMcGRDDQQGVVAGDYIVNVLKAKKVAVIHDKDTYGQGLADAT 185
Cdd:cd06328 79 AVALALAPVAEQNKKILIVGPAAADSITGENWNkYTFRT-SRNSWQDAIAGAKALADPLGKSVAFLAQDYAFGQDGVAAF 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 186 RAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGL 245
Cdd:cd06328 158 KKALEAKGGKIVGEELVPVTTTDFTPYLQRILDAKPDVLFVAWAGTGALTLWQQLADQGV 217
|
|
| PBP1_FmdD-like |
cd06355 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
55-296 |
3.54e-14 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF), found in Methylophilus methylotrophus, and its homologs from other bacteria. FmdD, a type 1 periplasmic binding protein, is induced by short-chain amides and urea and repressed by excess ammonia, while FmdE and FmdF are hydrophobic transmembrane proteins. FmdDEF is predicted to be an ATP-dependent transporter and closely resembles the periplasmic binding protein and the two transmembrane proteins present in various hydrophobic amino acid-binding transport systems.
Pssm-ID: 380578 [Multi-domain] Cd Length: 347 Bit Score: 72.61 E-value: 3.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 55 AAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTIPASEVYDEAGIIAITPG------- 127
Cdd:cd06355 26 AIDEINAAGGLLGRKIEPVIEDGASDWPTFAEKAEKLITQDKVAVIFGCWTSASRKAVLPVIEKYNGLLFYPVqyegleq 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 128 STNpqvterglsgMFRMCGRDDQQGVVAGDYIVNVLkAKKVAVIHDKDTYGQGLADATRAQLNKLGVKEVLYEGLTRGEK 207
Cdd:cd06355 106 SPN----------IVYTGATPNQQILPAIDWLLENL-GKRFFLVGSDYVFPRTANKIIRDQLKALGGEVVGEEYVPLGGT 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 208 DFNALVTKIRASGAEVVyFGGLHPEA-GPLVRQMREQGLTARFMSDDGVVTDELATTAGGPQYVKGVLMTFGADPRL-IP 285
Cdd:cd06355 175 DFDAIVAKIKAFKPDVI-VNTLNGDSnIAFFKQLAAAGITASDLPVLSFSVSEAELRAIGPEELAGHYAAWNYFQSLdTP 253
|
250
....*....|.
gi 15600106 286 DGKAVVEKFRA 296
Cdd:cd06355 254 ENQAFVEAFKA 264
|
|
| PBP1_NHase |
cd06358 |
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively ... |
31-225 |
1.24e-12 |
|
type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides; This group includes the type 1 periplasmic-binding protein of the nitrile hydratase (NHase) system that selectively converts nitriles to corresponding amides, which are subsequently converted by amidases to yield free carboxylic acids and ammonia. NHases from bacteria and fungi have been purified and characterized. In Rhodococcus sp., the nitrile hydratase operon consists of six genes encoding NHase regulator 2, NHase regulator 1, amidase, NHase alpha subunit, NHase beta subunit, and NHase activator. The operon produces a constitutive hydratase that has a broad substrate spectrum: aliphatic and aromatic nitriles, mononitriles and dinitriles, hydroxynitriles and amino-nitriles, and a constitutive amidase of equally low substrate specificity. NHases are metalloenzymes containing either cobalt or iron, and therefore can be classified into two subgroups: ferric NHases and cobalt NHases.
Pssm-ID: 380581 [Multi-domain] Cd Length: 333 Bit Score: 68.00 E-value: 1.24e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd06358 2 IGLLIPLSGPAGLWGPSCEACAELAAAEINAAGGILGREVELVLIDAGGPPAEVAAAARRLVDDGAVDAIVGMHTSAVRQ 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASE--------VY--------DEAGIIAItpGSTNPQVTERGLSgmfRMCgrdDQQGV-----VAGDYIvnvlkakkva 169
Cdd:cd06358 82 ALANavggrvpyVYtplyeggeRTPGVYAI--GETPEEQLRPALR---WLA---DERRVrrwflVGNDYV---------- 143
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 15600106 170 vihdkdtYGQGLADATRAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVY 225
Cdd:cd06358 144 -------WPRASHAAARRYIARLGGEVVGERFVPLGEDDFERVLARIRASRPDAVL 192
|
|
| PBP1_Nba-like |
cd06359 |
type 1 periplasmic binding component of active transport systems predicted to be involved in ... |
31-315 |
1.43e-12 |
|
type 1 periplasmic binding component of active transport systems predicted to be involved in 2-nitrobenzoic acid degradation pathway; This group includes the type 1 periplasmic binding component of active transport systems that are predicted to be involved in 2-nitrobenzoic acid degradation pathway; their substrate specificities are not well characterized.
Pssm-ID: 380582 [Multi-domain] Cd Length: 333 Bit Score: 68.05 E-value: 1.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINaaGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTI 110
Cdd:cd06359 2 IGFITTLSGPAAVLGQDMRDGFNLALEQLG--GKLGGLPVEVVVEDDQLKPDVAKQAAERLIERDKVDFVTGIIFSNVML 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGLS-GMFRMCGRDDQQGVVAGDYiVNVLKAKKVAVIHDKDTYGQGLADatraql 189
Cdd:cd06359 80 AVVKPVVDSKVFYISANAGPSDLAGKGCNpNFFVTSWQNDQLHEAAGKY-ANDKGYKRVYLLAPNYQAGKDALA------ 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 190 nklGVK-----EVLYEGLTR-GEKDFNALVTKIRASGAEVVYF---GGLhpeAGPLVRQMREQGLTAR------FMSDDG 254
Cdd:cd06359 153 ---GFKrtykgEVVGEIYTPlGQLDFSAELAQIRAAKPDAVFAfypGGM---GVNFVKQYAQAGLKKKiplytvGTLDDE 226
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 15600106 255 VVTDELATTAggpqyvKGVLMTFGADPRL-IPDGKAVVEKFRAG-GFEPEGYTLYSYASIQSL 315
Cdd:cd06359 227 DLLPAMGDAA------LGVLSVSQWSPDLdNPENKRFVAAFRKKyGRPPSNYAAQGYDAALLI 283
|
|
| PBP1_SBP-like |
cd06327 |
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins ... |
52-276 |
1.79e-12 |
|
periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs); Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380550 [Multi-domain] Cd Length: 336 Bit Score: 67.60 E-value: 1.79e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 52 ASQAAEDinAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTIPASEVYDEAGIIAITPGSTNP 131
Cdd:cd06327 24 AKMAVED--FGGKVLGRPIEVVSADHQNKPDVASAIAREWYDRDGVDAIVDVPNSAVALAVQKLAKEKKKIAIVTGAGSS 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 132 QVTERGLSGMFRMCGRDD-QQGVVAGDYIVNVLKaKKVAVIHDKDTYGQGLADATRAQLNKLGVKEVlyeGLTR---GEK 207
Cdd:cd06327 102 DLTGKACSPYGVHWAYDTyALARGTVKALVKQGG-KSWFFITADYAFGHSLEADATAAVKAAGGKVV---GSVRhplGTT 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 15600106 208 DFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGPQYVKGVLMT 276
Cdd:cd06327 178 DFSSFLLQAQASGADVIALANAGADLVNAVKQAREFGLTDGGQKLAALLLFITDIHALGLDAAQGLYLT 246
|
|
| PBP1_SBP-like |
cd20378 |
periplasmic substrate-binding domain of active transport proteins; Periplasmic ... |
30-351 |
1.33e-11 |
|
periplasmic substrate-binding domain of active transport proteins; Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.
Pssm-ID: 380668 [Multi-domain] Cd Length: 357 Bit Score: 65.06 E-value: 1.33e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 30 VIGVAGPHTGANASFGEQYWRGASQAAEdinAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd20378 1 TLGGLVSMSGAFAAAGKLADRGMRLAVE---EYGGALGRPLKYITRDTEGKPGTGVRKVQEAIAQDGARFFIGGTLSSVA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVTERGLSGMFRMCgrddqqgvvAGDY------IVNVL----KAKKVAVIHDKDTYGQ 179
Cdd:cd20378 78 LAVSEEAEKAGGVYITSGGADEITGSRCNRSTFRWS---------VPTYgairqtVRPVIkampKAKRWYTITPQYVFGE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 180 GLADATRAQLNKLGVKEV--LYEGLtrGEKDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARfmsddgvVT 257
Cdd:cd20378 149 SLLKNAKEVLKEKGIEHVgnSYHSL--GEREFSGYLTKAMAARPDVLLILNFGSQAVDALRQAVSFGLKRK-------MK 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 258 DELATTAG-------GPQYVKGVLmtFGA------DPrliPDGKAVVEKFRAGGFEPEGYTL-YSYASIQSLAAAFNGAG 323
Cdd:cd20378 220 ILVAWSSGldqfqelGPDICEGVY--FGAqywhdvDT---PANKALVKVYQAKFKETPSYALaAGYACTRMLLDAIDKAG 294
|
330 340
....*....|....*....|....*...
gi 15600106 324 ANDPAKAAEWLKSHPVQTVMGKKEWDKK 351
Cdd:cd20378 295 STDPAAVIKALEGLKYDGITGDEEVRAA 322
|
|
| PBP1_YraM_LppC_lipoprotein-like |
cd06339 |
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup ... |
31-218 |
2.08e-11 |
|
periplasmic binding component of lipoprotein LppC, an immunodominant antigen; This subgroup includes periplasmic binding component of lipoprotein LppC, an immunodominant antigen, whose molecular function is not characterized. Members of this subgroup are predicted to be involved in transport of lipid compounds, and they are sequence similar to the family of ABC-type hydrophobic amino acid transporters (HAAT).
Pssm-ID: 380562 [Multi-domain] Cd Length: 331 Bit Score: 64.21 E-value: 2.08e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINaagginGEKIKLVKADDAcEPKQAVAVANRLVdQDKAIAVVGHFCSSSTI 110
Cdd:cd06339 2 IALLLPLSGPYAAAGQAIRDGIELALFDAG------GSRPELRVYDTG-GPEGAAAAYQQAV-AEGADLIIGPLLKSSVA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 111 PASEVYDEAGIIAITPGSTNPQVTERGLsgmFRMCGRDDQQGVVAGDYIVNVLKaKKVAVIHDKDTYGQGLADATRAQLN 190
Cdd:cd06339 74 ALAAAAQALGVPVLALNNDESATAGPGL---FQFGLSPEDEARQAARYAVQQGL-RRFAVLAPDNAYGQRVANAFREAWQ 149
|
170 180
....*....|....*....|....*...
gi 15600106 191 KLGVKEVLYEGLTRGEKDFNALVTKIRA 218
Cdd:cd06339 150 ALGGTVVAVESYDPDETDFSAAIRRLLG 177
|
|
| PBP1_amide_urea_BP-like |
cd06356 |
periplasmic component (FmdD) of an active transport system for short-chain amides and urea ... |
38-230 |
6.76e-10 |
|
periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); This group includes the type 1 periplasmic-binding proteins that are predicted to have a function similar to that of an active transport system for short chain amides and/or urea in bacteria and Archaea, by sequence comparison and phylogenetic analysis.
Pssm-ID: 380579 [Multi-domain] Cd Length: 334 Bit Score: 59.62 E-value: 6.76e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 38 TGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTIPASEVYD 117
Cdd:cd06356 9 SGGLNIYGKPMVHAMKLAVEEINAAGGLLGRQIELVAYDTQSDMQKYTQYAQQLILRDKVDVVFGGITSASREAIRPILR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 118 EAGIIAITpgstnPQVTERGLSGMFRMCgrddqQGVVAGDYIVNVLK------AKKVAVIHDKDTYGQGLADATRAQLNK 191
Cdd:cd06356 89 RNKILYFY-----NTQYEGGVCDKNTFC-----TGSTPEQQVSPLIEwaikkyGKKVYIIAADYNFGQISADWVKKYAKK 158
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 15600106 192 LGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVY---FGGLH 230
Cdd:cd06356 159 NGGEVVGEEFFPLDVTDFGPTIQKIQAAKPDFVVsllVGGNH 200
|
|
| Peripla_BP_5 |
pfam13433 |
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic ... |
55-296 |
1.13e-09 |
|
Periplasmic binding protein domain; This domain is found in a variety of bacterial periplasmic binding proteins.
Pssm-ID: 463875 [Multi-domain] Cd Length: 363 Bit Score: 59.14 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 55 AAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTIPASEVYDEAGIIAITPgstnpqVT 134
Cdd:pfam13433 27 AIEEINAAGGVLGRKIEPVVVDPASDWPLFAEKARKLIDQDKVRVVFGCWTSASRKAVLPVFERHNGLLFYP------VQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 135 ERGLSgmfrmCGRD--------DQQGVVAGDYIVNVLKaKKVAVIHDKDTYGQGLADATRAQLNKLGVKEVLYEGLTRGE 206
Cdd:pfam13433 101 YEGFE-----SSRNifytgaapNQQAIPAVDYLLSELG-KRFFLVGSDYVYPRTTNRILRAYLKAKGGEVVGERYLPLGS 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 207 KDFNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTARFMSDDGVVTDELATTAGGPQYVKGVLMT---FGADPRl 283
Cdd:pfam13433 175 SDWQSIVAKIKAAGPDVVFSTINGDSNVAFYRALRAAGITAEDIPVMSFSVAEEELAGMGPEPLVGHLAAwnyFQSLDT- 253
|
250
....*....|...
gi 15600106 284 iPDGKAVVEKFRA 296
Cdd:pfam13433 254 -PENKAFVAAFKA 265
|
|
| PBP1_GPCR_family_C-like |
cd06350 |
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory ... |
92-253 |
4.91e-09 |
|
ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate; categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (m; Ligand-binding domain of membrane-bound glutamate receptors that mediate excitatory transmission on the cellular surface through initial binding of glutamate and are categorized into ionotropic glutamate receptors (iGluRs) and metabotropic glutamate receptors (mGluRs). The metabotropic glutamate receptors (mGluR) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. The mGluRs are coupled to G proteins and are thus distinct from the iGluRs which internally contain ligand-gated ion channels. The mGluR structure is divided into three regions: the extracellular region, the seven-spanning transmembrane region and the cytoplasmic region. The extracellular region is further divided into the ligand-binding domain (LBD) and the cysteine-rich domain. The LBD has sequence similarity to the LIVBP, which is a bacterial periplasmic protein (PBP), as well as to the extracellular region of both iGluR and the gamma-aminobutyric acid (GABA)b receptor. iGluRs are divided into three main subtypes based on pharmacological profile: NMDA, AMPA, and kainate receptors. All family C GPCRs have a large extracellular N terminus that contain a domain with homology to bacterial periplasmic amino acid-binding proteins.
Pssm-ID: 380573 Cd Length: 350 Bit Score: 57.31 E-value: 4.91e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 92 VDQDKAIAVVGHFCSSSTIPASEVYDEAGIIAITPGSTNPQVTERGLSGMF-RMCGRDDQQG-VVAGdyIVNVLKAKKVA 169
Cdd:cd06350 90 IGPPNIVAVIGAASSSVSIAVANLLGLFKIPQISYASTSPELSDKIRYPYFlRTVPSDTLQAkAIAD--LLKHFNWNYVS 167
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 170 VIHDKDTYGQGLADATRAQLNKLGV----KEVLYEGLTrgEKDFNALVTKIRASGAE--VVYFgGLHPEAGPLVRQMREQ 243
Cdd:cd06350 168 TVYSDDDYGRSGIEAFEREAKERGIciaqTIVIPENST--EDEIKRIIDKLKSSPNAkvVVLF-LTESDARELLKEAKRR 244
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170
....*....|...
gi 15600106 244 GLTaRFM---SDD 253
Cdd:cd06350 245 NLT-GFTwigSDG 256
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| PBP1_AmiC |
cd06357 |
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding ... |
31-108 |
9.81e-09 |
|
periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family; This group includes the periplasmic binding domain of amidase (AmiC) that belongs to the type 1 periplasmic binding fold protein family. AmiC controls expression of the amidase operon by the ligand-triggered conformational switch. In the absence of ligand or presence of butyramide (repressor), AmiC (the ligand sensor and negative regulator) adopts an open conformation and inhibits the transcription antitermination function of AmiR by direct protein-protein interaction. In the presence of inducing ligands such as acetamide, AmiC adopts a closed conformation which disrupts a silencing AmiC-AmiR complex and the expression of amidase and other genes of the operon are induced.
Pssm-ID: 380580 [Multi-domain] Cd Length: 357 Bit Score: 56.43 E-value: 9.81e-09
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 15600106 31 IGVAGPHTGANASFGEQYWRGASQAAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSS 108
Cdd:cd06357 2 VGLLFSQTGVTAIIEQSMLNGALLAIEEINAAGGVNGRPIEPVVYDPASDPDRYRELAERLLLEDGVRHIFGCYTSAS 79
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| PBP1_glutamate_receptors-like |
cd06269 |
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl ... |
55-271 |
1.02e-07 |
|
ligand-binding domain of family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as natriuretic peptide receptors (NPRs), and N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of ionotropic glutamate rece; This CD represents the ligand-binding domain of the family C G-protein couples receptors (GPCRs), membrane bound guanylyl cyclases such as the family of natriuretic peptide receptors (NPRs), and the N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the ionotropic glutamate receptors, all of which are structurally similar and related to the periplasmic-binding fold type 1 family. The family C GPCRs consists of metabotropic glutamate receptor (mGluR), a calcium-sensing receptor (CaSR), gamma-aminobutyric acid receptor (GABAbR), the promiscuous L-alpha-amino acid receptor GPR6A, families of taste and pheromone receptors, and orphan receptors. Truncated splicing variants of the orphan receptors are not included in this CD. The family C GPCRs are activated by endogenous agonists such as amino acids, ions, and sugar based molecules. Their amino terminal ligand-binding region is homologous to the bacterial leucine-isoleucine-valine binding protein (LIVBP) and a leucine binding protein (LBP). The ionotropic glutamate receptors (iGluRs) have an integral ion channel and are subdivided into three major groups based on their pharmacology and structural similarities: NMDA receptors, AMPA receptors, and kainate receptors. The family of membrane bound guanylyl cyclases is further divided into three subfamilies: the ANP receptor (GC-A)/C-type natriuretic peptide receptor (GC-B), the heat-stable enterotoxin receptor (GC-C)/sensory organ specific membrane GCs such as retinal receptors (GC-E, GC-F), and olfactory receptors (GC-D and GC-G).
Pssm-ID: 380493 [Multi-domain] Cd Length: 332 Bit Score: 53.19 E-value: 1.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 55 AAEDINAAGGI-NGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTIPASEVYDEAGIIAITPGSTNPQV 133
Cdd:cd06269 25 ALSDVNSRPDLlPKTTLGLAIRDSECNPTQALLSACDLLAAAKVVAILGPGCSASAAPVANLARHWDIPVLSYGATAPGL 104
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 134 TERGLSGMF-RMCGRDDQQGVVAGDyIVNVLKAKKVAVIHDKDTYG----QGLADATRAQLNKLGVKEVLYEGLTrgeKD 208
Cdd:cd06269 105 SDKSRYAYFlRTVPPDSKQADAMLA-LVRRLGWNKVVLIYSDDEYGefglEGLEELFQEKGGLITSRQSFDENKD---DD 180
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170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 15600106 209 FNALVTKIRASGAEVVYFGGLHPEAGPLVRQMREQGLTA---------RFMSDDGVVTDELATTAGGPQYVK 271
Cdd:cd06269 181 LTKLLRNLRDTEARVIILLASPDTARSLMLEAKRLDMTSkdyvwfvidGEASSSDEHGDEARQAAEGAITVT 252
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| PBP1_RPA0985_benzoate-like |
cd20013 |
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the ... |
31-245 |
1.89e-07 |
|
type 1 periplasmic binding-protein component of an ABC system (RPA0985), involved in the active transport of lignin-derived benzoate derivative compounds, and its close homologs; This group includes RPA0985 from Rhodopseudomonas palustris and its close homologs in other bacteria. Rpa0985 is the periplasmic binding-protein component of an ABC system that is involved in the active transport of lignin-derived benzoate derivative compounds. Members of this group has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP).
Pssm-ID: 380666 [Multi-domain] Cd Length: 356 Bit Score: 52.26 E-value: 1.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGEQYWRGAsQAAEDINAaGGINGEKIKLVKADDA-CEPKQAVAVANRLVDQDKAIAVVGHFCSSST 109
Cdd:cd20013 2 VGVIGPFSGPFADYGKQFDRGI-DLYLKLHG-DKVGGRKVEVIYRDDGgPNPAVAKRLAQELIVRDKVQILIGFGFTPNA 79
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 110 IPASEVYDEAGIIAITPGSTNPQVTERglSGMF-RMCGRDDQQGVVAGDYIVNVlKAKKVAVIHDKDTYGQGLADATRAQ 188
Cdd:cd20013 80 LAVAPVATEAKTPTVIMNAATSSITRK--SPYFvRTSFTMWQVAYPMGKWAAKN-GIKKAYTAVADYAPGHDAETAFKKA 156
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170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 189 LNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVYF---GGlhPEAGPLVRQMREQGL 245
Cdd:cd20013 157 FEAAGGKIVGSIRVPLATPDFAPFMQRIKDAKPDAVFVfvpAG--APSIGFLKAYAERGL 214
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| PBP1_ABC_ligand_binding-like |
cd06337 |
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type ... |
31-248 |
5.68e-07 |
|
type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions; This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.
Pssm-ID: 380560 [Multi-domain] Cd Length: 354 Bit Score: 50.76 E-value: 5.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 31 IGVAGPHTGANASFGE--QYWrgASQAAEDINAAGGINGEK---IKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFC 105
Cdd:cd06337 2 IGRVSPLTGPLAAFGEadPWV--LEQIREAFADGGIKVGGKkypVEIVVRDSQSDPNRAGEAARDLILRDKVDLMLASGT 79
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 106 SSSTIPASEVYDEAGIIAITpgSTNP-QVTERGLSG----MFRMC-----GRDDqqgvVAGDYI-------VNvlkaKKV 168
Cdd:cd06337 80 PDTVNPVADQCEANGVPCIS--TDAPwQAWFFGRGGdpakGFKWTfhffwGLED----IAANFLgmwdqvpTN----KVV 149
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170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 169 AVIHDKDTYGQGLADATRAQLNKLGVKEVLYEGLTRGEKDFNALVTKIRASGAEVVyFGGLH-PEAGPLVRQMREQGLTA 247
Cdd:cd06337 150 GLLWPNDPDGTAFADAFLGLPAAAGYTLVDPGRFPPGTDDFSSIINAFKKAGVEIV-TGVMIpPDFATFWRQAAQQGFKP 228
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.
gi 15600106 248 R 248
Cdd:cd06337 229 K 229
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| PBP1_GABAb_receptor_plant |
cd19990 |
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close ... |
55-181 |
1.12e-05 |
|
periplasmic ligand-binding domain of Arabidopsis thaliana glutamate receptors and its close homologs in other plants; This group includes the ligand-binding domain of Arabidopsis thaliana glutamate receptors, which have sequence similarity with animal ionotropic glutamate receptor and its close homologs in other plants. The ligand-binding domain of GABAb receptors are metabotropic transmembrane receptors for gamma-aminobutyric acid (GABA). GABA is the major inhibitory neurotransmitter in the mammalian CNS and, like glutamate and other transmitters, acts via both ligand gated ion channels (GABAa receptors) and G-protein coupled receptors (GABAb receptor or GABAbR). GABAa receptors are members of the ionotropic receptor superfamily which includes alpha-adrenergic and glycine receptors. The GABAb receptor is a member of a receptor superfamily which includes the mGlu receptors. The GABAb receptor is coupled to G alpha-i proteins, and activation causes a decrease in calcium, an increase in potassium membrane conductance, and inhibition of cAMP formation. The response is thus inhibitory and leads to hyperpolarization and decreased neurotransmitter release, for example.
Pssm-ID: 380645 [Multi-domain] Cd Length: 373 Bit Score: 46.84 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 55 AAEDINAAGGINGEKIKLVKADDACEPKQAVAVANRLVDQDKAIAVVGHFCSSSTIPASEVYDEAGIIAITPGSTNPQVT 134
Cdd:cd19990 23 AVSDFNSDSSSYGTKLVLHVRDSKGDPLQAASAALDLIKNKKVEAIIGPQTSEEASFVAELGNKAQVPIISFSATSPTLS 102
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 15600106 135 ERGLSGMFRMCGRDDQQ--GVVAgdyIVNVLKAKKVAVIHDKDTYGQGL 181
Cdd:cd19990 103 SLRWPFFIRMTHNDSSQmkAIAA---IVQSYGWRRVVLIYEDDDYGSGI 148
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|
| PBP1_mGluR |
cd06362 |
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of ... |
95-253 |
1.99e-04 |
|
ligand binding domain of metabotropic glutamate receptors (mGluR); Ligand binding domain of the metabotropic glutamate receptors (mGluR), which are members of the family C of G-protein-coupled receptors that transduce extracellular signals into G-protein activation and ultimately into cellular responses. mGluRs bind to glutamate and function as an excitatory neurotransmitter; they are involved in learning, memory, anxiety, and the perception of pain. Eight subtypes of mGluRs have been cloned so far, and are classified into three groups according to their sequence similarities, transduction mechanisms, and pharmacological profiles. Group I is composed of mGlu1R and mGlu5R that both stimulate PLC hydrolysis. Group II includes mGlu2R and mGlu3R, which inhibit adenylyl cyclase, as do mGlu4R, mGlu6R, mGlu7R, and mGlu8R, which form group III.
Pssm-ID: 380585 [Multi-domain] Cd Length: 460 Bit Score: 43.05 E-value: 1.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 95 DKAIAVVGHFCSSSTIPASEVYDEAGIIAITPGSTNPQVTERGLSGMF-RMCGRDDQQGVVagdyIVNVLKA---KKVAV 170
Cdd:cd06362 106 YDVVGVIGAESSSVSIQVANLLRLFKIPQISYASTSDELSDKERYPYFlRTVPSDSFQAKA----IVDILLHfnwTYVSV 181
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90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15600106 171 IHDKDTYGQGLADATRAQLNKLGV----KEVLYEGltRGEKDFNALVTKIRASGAE--VVYFGGLHpEAGPLVRQMREQG 244
Cdd:cd06362 182 VYSEGSYGEEGYKAFKKLARKAGIciaeSERISQD--SDEKDYDDVIQKLLQKKNArvVVLFADQE-DIRGLLRAAKRLG 258
|
170
....*....|..
gi 15600106 245 LTARFM---SDD 253
Cdd:cd06362 259 ASGRFIwlgSDG 270
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