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Conserved domains on  [gi|15829307|ref|NP_308080|]
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CcdB-like protein [Escherichia coli O157:H7 str. Sakai]

Protein Classification

CcdB family protein( domain architecture ID 10486789)

CcdB family protein similar to Escherichia coli type II toxin-antitoxin (TA) system toxin CcdB, the toxic component of a TA system that functions in plasmid maintenance; it is responsible for the post-segregational killing (PSK) of plasmid-free cells and its toxicity is inhibited by labile antitoxin CcdA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CcdB pfam01845
CcdB protein;
2-102 1.50e-38

CcdB protein;


:

Pssm-ID: 426470  Cd Length: 99  Bit Score: 124.19  E-value: 1.50e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15829307     2 QFTVYRSRSR-NAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRirPPERLNPILLlVDGKEYVLMTHETATVPVNALG 80
Cdd:pfam01845   1 QFDVYRNPGAsAKLYPYLLDVQSDLLDDLNTRVVIPLLPLSAFPK--PPRRLNPVFE-VEGESYVLMTPEMASVPARLLG 77

                          90       100
                  ....*....|....*....|..
gi 15829307    81 TKFCDASAHRTLIKGALDFMLD 102
Cdd:pfam01845  78 KPVASLSEHRDEIIAALDFLFT 99
 
Name Accession Description Interval E-value
CcdB pfam01845
CcdB protein;
2-102 1.50e-38

CcdB protein;


Pssm-ID: 426470  Cd Length: 99  Bit Score: 124.19  E-value: 1.50e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15829307     2 QFTVYRSRSR-NAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRirPPERLNPILLlVDGKEYVLMTHETATVPVNALG 80
Cdd:pfam01845   1 QFDVYRNPGAsAKLYPYLLDVQSDLLDDLNTRVVIPLLPLSAFPK--PPRRLNPVFE-VEGESYVLMTPEMASVPARLLG 77

                          90       100
                  ....*....|....*....|..
gi 15829307    81 TKFCDASAHRTLIKGALDFMLD 102
Cdd:pfam01845  78 KPVASLSEHRDEIIAALDFLFT 99
PRK13708 PRK13708
type II toxin-antitoxin system toxin CcdB;
1-104 9.49e-16

type II toxin-antitoxin system toxin CcdB;


Pssm-ID: 184264  Cd Length: 101  Bit Score: 66.40  E-value: 9.49e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15829307    1 MQFTVYRSRsRNAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRiRPPERLNPiLLLVDGKEYVLMTHETATVPVNALG 80
Cdd:PRK13708   1 MQFKVYTYK-RESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD-KVSRELYP-VVHIGDESYRLMTTDMASVPVSVIG 77

                         90       100
                 ....*....|....*....|....
gi 15829307   81 TKFCDASAHRTLIKGALDFMLDGI 104
Cdd:PRK13708  78 EEVADLSHRENDIKNAINLMFWGI 101
 
Name Accession Description Interval E-value
CcdB pfam01845
CcdB protein;
2-102 1.50e-38

CcdB protein;


Pssm-ID: 426470  Cd Length: 99  Bit Score: 124.19  E-value: 1.50e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15829307     2 QFTVYRSRSR-NAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRirPPERLNPILLlVDGKEYVLMTHETATVPVNALG 80
Cdd:pfam01845   1 QFDVYRNPGAsAKLYPYLLDVQSDLLDDLNTRVVIPLLPLSAFPK--PPRRLNPVFE-VEGESYVLMTPEMASVPARLLG 77

                          90       100
                  ....*....|....*....|..
gi 15829307    81 TKFCDASAHRTLIKGALDFMLD 102
Cdd:pfam01845  78 KPVASLSEHRDEIIAALDFLFT 99
PRK13708 PRK13708
type II toxin-antitoxin system toxin CcdB;
1-104 9.49e-16

type II toxin-antitoxin system toxin CcdB;


Pssm-ID: 184264  Cd Length: 101  Bit Score: 66.40  E-value: 9.49e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15829307    1 MQFTVYRSRsRNAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRiRPPERLNPiLLLVDGKEYVLMTHETATVPVNALG 80
Cdd:PRK13708   1 MQFKVYTYK-RESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD-KVSRELYP-VVHIGDESYRLMTTDMASVPVSVIG 77

                         90       100
                 ....*....|....*....|....
gi 15829307   81 TKFCDASAHRTLIKGALDFMLDGI 104
Cdd:PRK13708  78 EEVADLSHRENDIKNAINLMFWGI 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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