|
Name |
Accession |
Description |
Interval |
E-value |
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
5-738 |
0e+00 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 1386.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 5 AERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYE 84
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 85 AMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNI 164
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 165 LLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAV 244
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAEIIDKAEEIRKIYETGRGSFRMRAR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 245 WKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKS 324
Cdd:TIGR01062 241 WKKEDGQIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENPIRVVIVPRSNRVDPDIVMEHLFATTDLEKS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 325 YRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALM 404
Cdd:TIGR01062 321 YRLNMNMIGLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREEDEPKTILM 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 405 SRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQERE 484
Cdd:TIGR01062 401 ERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLARRSSLEERE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 485 EAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSAR 564
Cdd:TIGR01062 481 EAKQVSEIDMIPKEPVTIILSKMGWVRSAKGHDIDLSTLKYKAGDSEKAIIEGKSNQKVVFIDSTGRSYALDPDNLPSAR 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 565 GQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDASDMLL 644
Cdd:TIGR01062 561 GQGEPLTGKLLLPIGATITNILMYSPNQLLLMASDAGYGFLCNFNDLIARNKAGKALINLPENASVIAPLPVNGDSDMIA 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 645 AITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRR 724
Cdd:TIGR01062 641 AITEAGRMLVFPIDDLPELSKGKGNKLIRIPSANAKRGEDGLLDLKIFNKQDGLSWNDGKRKIQLEPEELQKFLGERGRF 720
|
730
....*....|....*
gi 15833157 725 G-TLMRGLQRIDRVE 738
Cdd:TIGR01062 721 GtTLPRGLPKNNRFS 735
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-737 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 1327.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS 80
Cdd:PRK05561 6 MLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHGDS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 81 ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSfAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR 160
Cdd:PRK05561 86 SIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPA-AAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 161 LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR 240
Cdd:PRK05561 165 FPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGEIITGRDGIRKAYETGRGSIR 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 241 MRAVWKKEDGA-----VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHL 315
Cdd:PRK05561 245 VRARWEIEDLAggrwqIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENPVRIVIEPKSNRVDPEALMNHL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 316 FATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRN 395
Cdd:PRK05561 325 FATTDLESSYRVNMNAIGLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRIIRE 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 396 EDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDD 475
Cdd:PRK05561 405 SDEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAKKFGDP 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 476 RRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAI 555
Cdd:PRK05561 485 RRTPIEEAEEAIAIDEEALIPDEPVTVVLSKKGWVRRAKGHSIDASGLSFKEGDSLLFAFEARTTDKLLLFTSTGRVYSL 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 556 DPITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVV 635
Cdd:PRK05561 565 PVHELPSARGDGEPLTGLVDLAPGEEIVHVLAFDPDQKLLLASSAGYGFVVTLEDLVARTRAGKAVINLKDGDEVLPPVP 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 636 IEDaSDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSaeaarGEDGLAQLYVLPPQSTL-TIHVGKRKIKLRPEEL 714
Cdd:PRK05561 645 VED-DDHLAAITSNGRLLVFPLSELPELGKGKGVKLINLPK-----DDDGLVDLRVLNPEDGLvLLTAGKRKLKLKPSEL 718
|
730 740
....*....|....*....|....
gi 15833157 715 QKVTGERGRRGTLM-RGLQRIDRV 737
Cdd:PRK05561 719 EKYRGKRARRGRLLpRGLKRVPRF 742
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-725 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 840.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 1 MSDMAER-----LALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYH 75
Cdd:COG0188 1 MSDPPPAeriipVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 76 PHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPD-DPKsfAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEP 154
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDgDPA--AAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 155 KMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIItSRAEIRKIYEN 234
Cdd:COG0188 159 TVLPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIV-GREGIREAYET 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 235 GRGSVRMRAVWKKEDG-----AVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDhENPTRLVIVPRSnRVDMD 309
Cdd:COG0188 238 GRGSIRVRAKAEIEELkrgreQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESD-RDGMRIVIELKR-DANPE 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 310 QVMNHLFATTDLEKSYRINLNMIgLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEV 389
Cdd:COG0188 316 VVLNQLYKHTQLQTSFGINMLAL-VDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEV 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 390 IEIIRNE---DEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQ 466
Cdd:COG0188 395 IAIIRASkdpDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 467 ADAQAYGDDRRSPLQEREEakAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDA--------PGLNYKAGDSFKAAVKGK 538
Cdd:COG0188 475 EIKKKYGDERRTEIEEAEG--EIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAqrrggkgvSGMGTKEEDFVEHLFVAS 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 539 SNQPVVFVDSTGRSYAIDPITLPSARGQ--GEPLTGKLTLPPGATVDHMLM---ESDDQKLLMASDAGYGFVCTFNDLVA 613
Cdd:COG0188 553 THDTLLFFTNKGRVYRLKVYELPEGSRTakGKPIVNLLPLEPGEKITAVLPvkeFDEDKYLLFATKKGTVKKTPLSDFSN 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 614 RNRAGKALITLPENAHVMPPVVIEDASDMLLaITQAGRMLMFPVSDLPQLS-KGKGNKIINIpsaeaaRGEDGLAQLYVL 692
Cdd:COG0188 633 IRKNGIIAINLKEGDELVGVALTDGDDDVLL-ATSNGKAIRFPESDVRPMGrTARGVRGIRL------KEGDEVVGMAVV 705
|
730 740 750
....*....|....*....|....*....|...
gi 15833157 693 PPQSTLTIHVGKRKIKLRPEELQKVTGeRGRRG 725
Cdd:COG0188 706 DEEDDLLTVTENGYGKRTPLSEYRLQG-RGGKG 737
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
27-467 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 619.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 27 MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNW 106
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 107 GAPDDpKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLR 186
Cdd:cd00187 81 GSRDG-DDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 187 EVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITsRAEIRKIYENGRGSVRMRAVWKKED----GAVVISALPHQVS 262
Cdd:cd00187 160 EVIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEG-RAGIREAYETGRGRYIIRGKYEIEDdegrNTIEITELPYQVN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 263 GARVLEQIAAQMRNKKLPMVDDLRDESDHeNPTRLVIVPRSNRVDmDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKN 342
Cdd:cd00187 239 KAKLKEKIAELVKDKKIEGISDVRDESDR-EGIRFVIELKRGAMA-EVVLNGLYKVTKLQTTFGINMVAFDPNGRPKKLN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 343 LLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRF---GLTETQAEAILE 419
Cdd:cd00187 317 LKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSDEAKKALIEELeklGFSEIQADAILD 396
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 15833157 420 LKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQA 467
Cdd:cd00187 397 MRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDE 444
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
10-458 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 591.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 10 LHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLM 89
Cdd:smart00434 3 IEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIVRM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 90 AQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGT 169
Cdd:smart00434 83 AQDFSNNYPLLDGQGNFGSRLDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVNGS 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 170 TGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIItsraeirkiyenGRGSVRMRAVWKKED 249
Cdd:smart00434 163 SGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV------------GPGKYVVRGKIEIED 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 250 G-AVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNrVDMDQVMNHLFATTDLEKSYRIN 328
Cdd:smart00434 231 DnTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRG-AMAEVVLNGLYKLTKLQTTFSIN 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 329 LNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKV-LKRLHILEGLLVAFLNIDEVIEIIRNEDEP----KPAL 403
Cdd:smart00434 310 MLALFDNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLeAERLHILEGLFIALSIIDEIIVLIRSSKDLakeaKEKL 389
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 15833157 404 MSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMN 458
Cdd:smart00434 390 MERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
29-466 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 555.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 29 RALPFIGDGLKPVQRRIVYAMSELgLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGA 108
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 109 PDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREV 188
Cdd:pfam00521 80 RIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 189 AQAAIALIDQPKTTLdqLLDIVQGPDYPTEAEIItSRAEIRKIYENGRGSVRMRAVWKKEDG-AVVISALPHQVSGARVL 267
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGII-GKGGIKEAYKTGRGKITVRAKVEIEDRkTIVITELPYGVWTSDLI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 268 EQIAAQMRNKKLPMVDDLRDESDheNPTRLVIVPRSNrVDMDQVMNHLFATTDLEKSYRINLNMIGlDGRPAVKNLLEIL 347
Cdd:pfam00521 237 EKIEELVKNGKIKGISDIRDESD--RGVRIVIELKRG-ADPEVVLNDLYKKTKLQTSFSTNNLVLF-DGGPKYLGLKEIL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 348 SEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNED---EPKPALMSRfgLTETQAEAILELKLRH 424
Cdd:pfam00521 313 KEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIdrkKAKKNLIEE--LSEIQADYLLDMRLRR 390
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 15833157 425 LAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQ 466
Cdd:pfam00521 391 LTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
5-738 |
0e+00 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 1386.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 5 AERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYE 84
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 85 AMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNI 164
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 165 LLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVRMRAV 244
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAGLDDILNIVQGPDFPTEAEIIDKAEEIRKIYETGRGSFRMRAR 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 245 WKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKS 324
Cdd:TIGR01062 241 WKKEDGQIVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENPIRVVIVPRSNRVDPDIVMEHLFATTDLEKS 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 325 YRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALM 404
Cdd:TIGR01062 321 YRLNMNMIGLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIREEDEPKTILM 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 405 SRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQERE 484
Cdd:TIGR01062 401 ERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYGLARRSSLEERE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 485 EAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSAR 564
Cdd:TIGR01062 481 EAKQVSEIDMIPKEPVTIILSKMGWVRSAKGHDIDLSTLKYKAGDSEKAIIEGKSNQKVVFIDSTGRSYALDPDNLPSAR 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 565 GQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDASDMLL 644
Cdd:TIGR01062 561 GQGEPLTGKLLLPIGATITNILMYSPNQLLLMASDAGYGFLCNFNDLIARNKAGKALINLPENASVIAPLPVNGDSDMIA 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 645 AITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRR 724
Cdd:TIGR01062 641 AITEAGRMLVFPIDDLPELSKGKGNKLIRIPSANAKRGEDGLLDLKIFNKQDGLSWNDGKRKIQLEPEELQKFLGERGRF 720
|
730
....*....|....*
gi 15833157 725 G-TLMRGLQRIDRVE 738
Cdd:TIGR01062 721 GtTLPRGLPKNNRFS 735
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
1-737 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 1327.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 1 MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS 80
Cdd:PRK05561 6 MLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHGDS 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 81 ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSfAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR 160
Cdd:PRK05561 86 SIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPA-AAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPAR 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 161 LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR 240
Cdd:PRK05561 165 FPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELMEFVPGPDFPTGGEIITGRDGIRKAYETGRGSIR 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 241 MRAVWKKEDGA-----VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHL 315
Cdd:PRK05561 245 VRARWEIEDLAggrwqIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDESDRENPVRIVIEPKSNRVDPEALMNHL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 316 FATTDLEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRN 395
Cdd:PRK05561 325 FATTDLESSYRVNMNAIGLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEVIRIIRE 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 396 EDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDD 475
Cdd:PRK05561 405 SDEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELKADAKKFGDP 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 476 RRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAI 555
Cdd:PRK05561 485 RRTPIEEAEEAIAIDEEALIPDEPVTVVLSKKGWVRRAKGHSIDASGLSFKEGDSLLFAFEARTTDKLLLFTSTGRVYSL 564
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 556 DPITLPSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVV 635
Cdd:PRK05561 565 PVHELPSARGDGEPLTGLVDLAPGEEIVHVLAFDPDQKLLLASSAGYGFVVTLEDLVARTRAGKAVINLKDGDEVLPPVP 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 636 IEDaSDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSaeaarGEDGLAQLYVLPPQSTL-TIHVGKRKIKLRPEEL 714
Cdd:PRK05561 645 VED-DDHLAAITSNGRLLVFPLSELPELGKGKGVKLINLPK-----DDDGLVDLRVLNPEDGLvLLTAGKRKLKLKPSEL 718
|
730 740
....*....|....*....|....
gi 15833157 715 QKVTGERGRRGTLM-RGLQRIDRV 737
Cdd:PRK05561 719 EKYRGKRARRGRLLpRGLKRVPRF 742
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
1-725 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 840.85 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 1 MSDMAER-----LALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYH 75
Cdd:COG0188 1 MSDPPPAeriipVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYH 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 76 PHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGAPD-DPKsfAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEP 154
Cdd:COG0188 81 PHGDSAVYDALVRMAQDFSMRYPLVDGQGNFGSIDgDPA--AAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 155 KMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIItSRAEIRKIYEN 234
Cdd:COG0188 159 TVLPARFPNLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELMEYIPGPDFPTGGIIV-GREGIREAYET 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 235 GRGSVRMRAVWKKEDG-----AVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDhENPTRLVIVPRSnRVDMD 309
Cdd:COG0188 238 GRGSIRVRAKAEIEELkrgreQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDESD-RDGMRIVIELKR-DANPE 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 310 QVMNHLFATTDLEKSYRINLNMIgLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEV 389
Cdd:COG0188 316 VVLNQLYKHTQLQTSFGINMLAL-VDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEV 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 390 IEIIRNE---DEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQ 466
Cdd:COG0188 395 IAIIRASkdpDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELL 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 467 ADAQAYGDDRRSPLQEREEakAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDA--------PGLNYKAGDSFKAAVKGK 538
Cdd:COG0188 475 EIKKKYGDERRTEIEEAEG--EIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAqrrggkgvSGMGTKEEDFVEHLFVAS 552
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 539 SNQPVVFVDSTGRSYAIDPITLPSARGQ--GEPLTGKLTLPPGATVDHMLM---ESDDQKLLMASDAGYGFVCTFNDLVA 613
Cdd:COG0188 553 THDTLLFFTNKGRVYRLKVYELPEGSRTakGKPIVNLLPLEPGEKITAVLPvkeFDEDKYLLFATKKGTVKKTPLSDFSN 632
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 614 RNRAGKALITLPENAHVMPPVVIEDASDMLLaITQAGRMLMFPVSDLPQLS-KGKGNKIINIpsaeaaRGEDGLAQLYVL 692
Cdd:COG0188 633 IRKNGIIAINLKEGDELVGVALTDGDDDVLL-ATSNGKAIRFPESDVRPMGrTARGVRGIRL------KEGDEVVGMAVV 705
|
730 740 750
....*....|....*....|....*....|...
gi 15833157 693 PPQSTLTIHVGKRKIKLRPEELQKVTGeRGRRG 725
Cdd:COG0188 706 DEEDDLLTVTENGYGKRTPLSEYRLQG-RGGKG 737
|
|
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
15-660 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 638.23 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 15 ENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFS 94
Cdd:PRK05560 15 KRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSAVYDALVRMAQDFS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 95 YRYPLVDGQGNWGAPD-DPKsfAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIA 173
Cdd:PRK05560 95 MRYPLVDGQGNFGSIDgDPA--AAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFPNLLVNGSSGIA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 174 VGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAeIITSRAEIRKIYENGRGSVRMRAVWKKEDG--- 250
Cdd:PRK05560 173 VGMATNIPPHNLGEVIDACLALIDNPDITIEELMEIIPGPDFPTGG-IILGRSGIREAYRTGRGSIVMRAKAEIEEIkgr 251
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 251 -AVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENpTRLVI------VPrsnrvdmDQVMNHLFATTDLEK 323
Cdd:PRK05560 252 eAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESDRDG-MRIVIelkrdaVP-------EVVLNNLYKHTQLQT 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 324 SYRInlNMIGL-DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEP 399
Cdd:PRK05560 324 SFGI--NMLALvDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRaspTPAEA 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 400 KPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSP 479
Cdd:PRK05560 402 KEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGDPRRTE 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 480 LQEREEakAMSEHDMLPSEPVTIVLSQMGWV------------RSAKGhdidAPGLNYKAGDSFKAAVKGKSNQPVVFVD 547
Cdd:PRK05560 482 IIEGEG--DIDDEDLIPEEDVVVTLTHGGYIkrtpldeyraqrRGGKG----VSGAKTKEDDFVEHLFVASTHDTLLFFT 555
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 548 STGRSYAID----PITLPSARGQgePLTGKLTLPPGATVDHMLMESDDqkllmaSDAGYGFVCTFNDLVARN-------- 615
Cdd:PRK05560 556 NRGRVYRLKvyeiPEASRTARGR--PIVNLLPLEPGEKITAILPVREF------DDDKYLFFATKNGTVKKTslsefsni 627
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 15833157 616 -RAGKALITLPENAHVMpPVVIEDASDMLLAITQAGRMLMFPVSDL 660
Cdd:PRK05560 628 rSNGIIAINLDEGDELI-GVRLTDGDDDILLATKNGKAIRFPESDV 672
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
27-467 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 619.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 27 MDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNW 106
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 107 GAPDDpKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLR 186
Cdd:cd00187 81 GSRDG-DDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 187 EVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITsRAEIRKIYENGRGSVRMRAVWKKED----GAVVISALPHQVS 262
Cdd:cd00187 160 EVIDALRALIDNPEASIDELMEIIKGPDFPTGGIIEG-RAGIREAYETGRGRYIIRGKYEIEDdegrNTIEITELPYQVN 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 263 GARVLEQIAAQMRNKKLPMVDDLRDESDHeNPTRLVIVPRSNRVDmDQVMNHLFATTDLEKSYRINLNMIGLDGRPAVKN 342
Cdd:cd00187 239 KAKLKEKIAELVKDKKIEGISDVRDESDR-EGIRFVIELKRGAMA-EVVLNGLYKVTKLQTTFGINMVAFDPNGRPKKLN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 343 LLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPALMSRF---GLTETQAEAILE 419
Cdd:cd00187 317 LKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSSDEAKKALIEELeklGFSEIQADAILD 396
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 15833157 420 LKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQA 467
Cdd:cd00187 397 MRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDE 444
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
15-666 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 598.91 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 15 ENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFS 94
Cdd:TIGR01063 11 KRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYDTLVRMAQDFS 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 95 YRYPLVDGQGNWGAPD-DPKsfAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIA 173
Cdd:TIGR01063 91 LRYPLVDGQGNFGSIDgDPP--AAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLVNGSSGIA 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 174 VGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIItSRAEIRKIYENGRGSVRMRA---VWKKEDG 250
Cdd:TIGR01063 169 VGMATNIPPHNLGEIIDALLAYIDNPDISIQELLEVIKGPDFPTGGIIL-GRSGIRSAYETGRGSIVIRAraeIEEDSKG 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 251 --AVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENpTRLVI-VPRSnrVDMDQVMNHLFATTDLEKSYRI 327
Cdd:TIGR01063 248 reAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDESDREG-IRIVIeLKRD--AVAEVVLNNLYKQTQLQVSFGI 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 328 nlNMIGL-DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NEDEPKPAL 403
Cdd:TIGR01063 325 --NMLALvKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRasqNTEEAKTRL 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 404 MSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPLQER 483
Cdd:TIGR01063 403 VERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEIVYD 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 484 EEAKAMSEhDMLPSEPVTIVLSQMGWV------------RSAKGhdidAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGR 551
Cdd:TIGR01063 483 ESEDIDIE-DLIARENVVVTLSHNGYVkrvpvsayrlqkRGGKG----VSGADMKDDDFIEQLLVASTHDYLLFFTNRGK 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 552 SYAIDPITLPSA--RGQGEPLTGKLTLPPGATVDHMLMESDDQkllmasDAGYGFVCTFNDLVAR--------NRA-GKA 620
Cdd:TIGR01063 558 VYWLKVYQIPEAsrTAKGKPIVNLLPLQPDERITAILSVKEFD------DGLYLFFATKNGVVKKtsltefsnIRSnGII 631
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 15833157 621 LITLPENAHVMpPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKG 666
Cdd:TIGR01063 632 AIKLDDGDELI-SVRLTSGEDEVMLGSKNGKAVRFPEEDVRPMGRA 676
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
10-458 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 591.08 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 10 LHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLM 89
Cdd:smart00434 3 IEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIVRM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 90 AQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGT 169
Cdd:smart00434 83 AQDFSNNYPLLDGQGNFGSRLDGDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVNGS 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 170 TGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIItsraeirkiyenGRGSVRMRAVWKKED 249
Cdd:smart00434 163 SGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMMIPWGPDFPTGGEIV------------GPGKYVVRGKIEIED 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 250 G-AVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNrVDMDQVMNHLFATTDLEKSYRIN 328
Cdd:smart00434 231 DnTIVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRG-AMAEVVLNGLYKLTKLQTTFSIN 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 329 LNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKV-LKRLHILEGLLVAFLNIDEVIEIIRNEDEP----KPAL 403
Cdd:smart00434 310 MLALFDNGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLeAERLHILEGLFIALSIIDEIIVLIRSSKDLakeaKEKL 389
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*
gi 15833157 404 MSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMN 458
Cdd:smart00434 390 MERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
29-466 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 555.24 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 29 RALPFIGDGLKPVQRRIVYAMSELgLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDGQGNWGA 108
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 109 PDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREV 188
Cdd:pfam00521 80 RIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 189 AQAAIALIDQPKTTLdqLLDIVQGPDYPTEAEIItSRAEIRKIYENGRGSVRMRAVWKKEDG-AVVISALPHQVSGARVL 267
Cdd:pfam00521 160 IDALIALLDGPEATL--LMKYIMGPDFPTGGGII-GKGGIKEAYKTGRGKITVRAKVEIEDRkTIVITELPYGVWTSDLI 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 268 EQIAAQMRNKKLPMVDDLRDESDheNPTRLVIVPRSNrVDMDQVMNHLFATTDLEKSYRINLNMIGlDGRPAVKNLLEIL 347
Cdd:pfam00521 237 EKIEELVKNGKIKGISDIRDESD--RGVRIVIELKRG-ADPEVVLNDLYKKTKLQTSFSTNNLVLF-DGGPKYLGLKEIL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 348 SEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNED---EPKPALMSRfgLTETQAEAILELKLRH 424
Cdd:pfam00521 313 KEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIdrkKAKKNLIEE--LSEIQADYLLDMRLRR 390
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 15833157 425 LAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQ 466
Cdd:pfam00521 391 LTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
8-733 |
1.32e-150 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 456.96 E-value: 1.32e-150
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 8 LALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMV 87
Cdd:TIGR01061 4 KPLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYDAMV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 88 LMAQPFSYRYPLVDGQGNWGAPD-DPKsfAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILL 166
Cdd:TIGR01061 84 RMSQDWKNNWTLVEMHGNNGSIDgDNA--AAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLLI 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 167 NGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAeIITSRAEIRKIYENGRGSVRMRAVWK 246
Cdd:TIGR01061 162 NGATGIAAGYATNIPPHNLNEVIDALIYRIDHPNCSVDKLMEIVKGPDFPTGG-IIQGEDGISKAYETGKGKFIIRAKIE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 247 KE--DGA---VVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDhENPTRLVIVPRSNrVDMDQVMNHLFATTDL 321
Cdd:TIGR01061 241 IEvnKNGlnqIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDESD-RNGIRIIIELKKD-ANAEKILNFLFKHTDL 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 322 EKSYriNLNMIGLDGR-PAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIR---NED 397
Cdd:TIGR01061 319 QINY--NFNMVAIANRtPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRsseDKS 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 398 EPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRR 477
Cdd:TIGR01061 397 DAKENLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQRR 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 478 SPLQEREEAKAMSEHDMLPSEPVTIVLSQMGWV-----RSAKGHDIDAPGLnyKAGDSFKAAVKGKSNQPVVFVDSTGRS 552
Cdd:TIGR01061 477 SQIEDFINQIKINESELIENEDYYVLITKAGYIkrtsnRSFASSKYTDFGS--KDDDILFAQTIANTTDQILIFTSLGNI 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 553 YAIDPITLPSARGQ--GEPLTGKLTLPPGATVDHM-LMESDDqkllmaSDAGYGFVCTFNDLVAR--------NRAGKAL 621
Cdd:TIGR01061 555 INIPVHKLADIRWKdlGEHLSNKITFDENETIVFVgTMNEFD------VDQPILVLASKLGMVKRieltelniKRNSKAT 628
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 622 --ITLPENAHVMPPVVIEDASDMLLaITQAGRMLMFPVSDLPQL-SKGKGNKIINIpsaeaaRGEDGLAQLYVLPPQSTL 698
Cdd:TIGR01061 629 lcIKLKDKDHLISAFLQQKDKLICL-VSDLGYALVFHTNEIPVVgAKAAGVKGMKL------KEDDQVKSGVIFEANESL 701
|
730 740 750
....*....|....*....|....*....|....*.
gi 15833157 699 TIHVGKRKIK-LRPEELQKVTgeRGRRGTLMRGLQR 733
Cdd:TIGR01061 702 VLLTQRGSVKrLSISELVVTS--RAATGKKLLPLKK 735
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
15-564 |
3.05e-140 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 436.46 E-value: 3.05e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 15 ENaYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFS 94
Cdd:PRK13979 24 EN-YLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYDAMVILAQDFT 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 95 YRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIAV 174
Cdd:PRK13979 103 TRMPLIDGHGNWGSIDG-DSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLLVNGAFGIAV 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 175 GMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTeAEIITSRAEIRKIYENGRGSVRMRA---VWKKEDG- 250
Cdd:PRK13979 182 GLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNYIKGPDLPT-GGILIGKKSLLSAYETGEGKVTLRAktkIEKLENGr 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 251 -AVVISALPHQVSGARVLEQIAAQMRNKK----LPMVDDLRDESDhENPTRLVI-VPRSNRVDM-DQVMNHLFATTDLEK 323
Cdd:PRK13979 261 lGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDESD-RNGIRAVIeFKKSADEDVaEKVLKYLYKKTDLQC 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 324 SyrINLNMIGL-DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPKPA 402
Cdd:PRK13979 340 N--ISFNMVALaDGKPETMGLKTMLKHYVEHQKEVVTRRTKKELEIAEKRFHIVEGFIKAIGIMDEIIKTIRSSKSKKDA 417
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 403 ---LMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSP 479
Cdd:PRK13979 418 senLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVKEKYGDERRTS 497
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 480 LQEREEAKAMSEHDMLPSEPVTIVLSQMGWVR----------SAKGHDIDapglnYKAGDSFKAAVKGKSNQPVVFVDST 549
Cdd:PRK13979 498 IIEDDEKAKIDVEELIVVEDVVITLSNEGFIKriplksynrsNSNVEDIE-----YREGDFNKFLIQSNTKDTLLIFTDK 572
|
570
....*....|....*
gi 15833157 550 GRSYAIDPITLPSAR 564
Cdd:PRK13979 573 GNMYQIKGINIPEFK 587
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
10-494 |
6.04e-57 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 205.71 E-value: 6.04e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 10 LHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGlnaSAKFKKSARTVGDVLgKYHPHGDSACYEAMVLM 89
Cdd:PRK09631 4 IKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSLFEMH---DGKFHKVANVVGNTM-KYHPHGDASIYEALVNL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 90 AQpfsyRYPLVDGQGNWGAP--DDPKSfaAMRYTESRLSKYS-ELLLS-ELgqgtADWVPNFDGTLQEPKMLPARLPNIL 165
Cdd:PRK09631 80 AN----KDLFIDKQGNFGNLftGDPAS--AARYIECRLTPLAkEVLYNkEI----TEYEPSYDGRNNEPLCLPAKIPVIL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 166 LNGTTGIAVGMATDIPPHNLREVAQAAIA-LIDQPKTTLdqlldivqgPDYPTEAEIITSRaeirkiYENGRGSVRMRA- 243
Cdd:PRK09631 150 IQGAEGIAVGMATKILPHNFNEILQAVKSeLLGESFALY---------PDFPTGGIVDVSE------YADGNGKVLVRAk 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 244 VWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPmVDDLRDESDhENPTRLVIVPRSnrVDMDQVMNHLFATTDLEK 323
Cdd:PRK09631 215 IETKDEKTIVIREIPFGTTTESLIASIEKAARKGKIK-ISSINDYTA-ENVEIEIKLPRG--VYASEVIEALYAYTDCEV 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 324 SYRINLNMIGlDGRPAV-----------KNLLEILSEWLVFRRDTVRRRLNYR-LEKVL--KRLH-ILEGLLVAflniDE 388
Cdd:PRK09631 291 SISVNLLVIK-DRYPVIytvtdiikfhaEHLQKVLKMELELERAKLLEKIFAKtLEQIFieERIYkRIETISSE----ED 365
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 389 VIEIIRNEDEPKPALMSRfGLTETQAEAILELKLRHLAKLEEMK----IRGEQSELEKERDQLQGILA-SERKMNNLLKK 463
Cdd:PRK09631 366 VISIVLSELKPFKEELSR-DVTEEDIENLLKIPIRRISLFDIDKnqkeIRILNKELKSVEKNLKSIKGyAINFIDKLLAK 444
|
490 500 510
....*....|....*....|....*....|....*
gi 15833157 464 elqadaqaYGDD--RRSPLQEREE--AKAMSEHDM 494
Cdd:PRK09631 445 --------YSKEypRKTEISLIKSvdVREIATKNL 471
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
15-476 |
2.49e-52 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 195.61 E-value: 2.49e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 15 ENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGlnaSAKFKKSARTVGDVLgKYHPHGDSACYEAMVLMAQpfs 94
Cdd:PRK12758 28 KNWFLDYASYVILERAVPHIEDGLKPVQRRILHSMKEMD---DGRYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ--- 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 95 yRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYS-ELLLSElgqGTADWVPNFDGTLQEPKMLPARLPNILLNGTTGIA 173
Cdd:PRK12758 101 -KDLLIDTQGNWGNILTGDGAAAPRYIEARLSKFAlEVVFNP---KTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIA 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 174 VGMATDIPPHNLREVAQAAIALIDQPKTTLdqlldivqGPDYPTEAEIITSRaeirkiYENGR--GSVRMRA-VWKKEDG 250
Cdd:PRK12758 177 VGLSTKILPHNFNELIDASIAYLKGKEFKL--------YPDFPTGGIIDVSN------YNDGErgGRVRVRAkIEKLDKK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 251 AVVISALPHQVSGARVLEQI-AAQMRNK-KLPMVDDLRDEsDHEnptrlVIVPRSNRVDMDQVMNHLFATTDLEKSYRIN 328
Cdd:PRK12758 243 TLVITEIPYGTTTSSLIDSIlKANDKGKiKIKKVEDNTAA-DVE-----ILVHLAPGVSPDKTIDALYAFTDCEVSISPN 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 329 LNMIgLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLH--------ILEGLLVAF---LNIDEVIEIIRNED 397
Cdd:PRK12758 317 ACVI-IDNKPHFLGVSDILRRSTDHTVSLLKQELEIRLSELEEQWHfaslekifIEERIYKEIeeaETWEAVIEAIDKGL 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 398 EPKPALMSRfGLTETQAEAILELKLRHLAKLE----EMKIRGEQSELEKERDQLQGILA-SERKMNNLLKKelqadaqaY 472
Cdd:PRK12758 396 EPFKKQFIR-EVTEDDIVRLTEIKIKRISKFDsdkaDELIARLEAEIAEVKHHLAHLTDyAIAYFTNLKKK--------Y 466
|
....
gi 15833157 473 GDDR 476
Cdd:PRK12758 467 GKGR 470
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
1-243 |
1.37e-38 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 150.05 E-value: 1.37e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 1 MSDMAERLALHeftenaYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGlnaSAKFKKSARTVGDVLGkYHPHGDS 80
Cdd:PRK09630 1 MSDVSDLFKTH------FMHYASYVILERAIPHILDGLKPVQRRLLWTLFRMD---DGKMHKVANIAGRTMA-LHPHGDA 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 81 ACYEAMVLMAQpfsyRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLseLGQGTADWVPNFDGTLQEPKMLPAR 160
Cdd:PRK09630 71 PIVEALVVLAN----KGYLIDTQGNFGNPLTGDPHAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAK 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 161 LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALI-DQPKTTLdqlldivqgPDYPTEAEIITSRaeirkiYENGRGSV 239
Cdd:PRK09630 145 LPLLLLHGVDGIAVGMTTKIFPHNFCELLEAQIAILnDQPFTLL---------PDFPSGGTMDASE------YQDGLGSI 209
|
....
gi 15833157 240 RMRA 243
Cdd:PRK09630 210 TLRA 213
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
10-449 |
4.57e-34 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 135.95 E-value: 4.57e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 10 LHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDV--LGkYHpHGDSACYEAMV 87
Cdd:PHA02592 8 LKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVadLG-YH-HGETSAQDAGA 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 88 LMAQPFSYRYPLVDGQGNWGAPDDPKSfAAMRYTESRLSKYSELLLSELgqgtaDWVPNFdgtlQEPKMLPAR-----LP 162
Cdd:PHA02592 86 LMANTWNNNIPLLDGQGNFGSRLVQKA-AAARYIFARVHDNFRKIYKDE-----DLAPVH----EDPEHIPPAfylpiIP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 163 NILLNGTTGIAVGMATDIPPHNLREVAQAAIALI-DQPKTTLDqlldiVQGPDYPTEAEIITS-RAEIRKIYE-NGRGSV 239
Cdd:PHA02592 156 MVLLNGVSGIATGYATNILPHSPKSVIKAVLAALnGKDITEPK-----VQFPEFKGEVVEIEPgSYEIRGTYElNGKTKL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 240 RMRAVWKKEDGAVVISALphqvsgarvleqiaaqmrnkkLPMVDD---LRDESDHENPTRLVIVPR---SNRVDMDQVMN 313
Cdd:PHA02592 231 HITEIPVKYDRETYVAVL---------------------DPLEEKgkiVSYDDCTEDGFRFKVTLKreeNEEATHEKIMK 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 314 HLfattDLEKSYRINLNMIGLDGRPAV-KNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILeGLLVAFLN--IDEVI 390
Cdd:PHA02592 290 DF----GLIERVSQNITVINENGKLKVyENAEDLIRDFVEIRKTYVQKRIQYEIKETEEAFDLA-LAKAEFIKrvIAGEI 364
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*....
gi 15833157 391 EIIRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQG 449
Cdd:PHA02592 365 VLQGKTRSELTEELSDNKDFGEYADKLVAMNIYSMTSDEREKLQKEAEELEKEHEYWKK 423
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
10-465 |
2.53e-23 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 106.28 E-value: 2.53e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 10 LHEFTENAYLNYSM---------------YVIMD--RALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVlG 72
Cdd:PTZ00108 644 ITNYKGGTYVDHSKkkltysdfvnkelilFSIADneRSIPSLVDGLKPGQRKILFACFKRNLKNEIKVAQLSGYVSEH-S 722
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 73 KYHpHGDSACYEAMVLMAQPF--SYRYPLV--DGQ-------GnwgapddpKSFAAMRYTESRLSKYSELLLSELGQGTA 141
Cdd:PTZ00108 723 AYH-HGEQSLQQTIVGMAQNFvgSNNINLLypCGQfgsrlqgG--------KDHAAARYIFTKLSKITRYIFPEEDDPIL 793
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 142 DWVpNFDGTLQEPKMLPARLPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALID-QPKTTLDQLLDIVQGpdypteae 220
Cdd:PTZ00108 794 DYL-EDDGQSVEPFYYVPIIPMVLVNGAEGIGTGFSTSIPNYNPLDIIDNLRRRLNgEEVRPLVPWYRGFKG-------- 864
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 221 iitsraeirKIYENGRGSVRMRAVWKK-EDGAVVISALPHQVSGARVLEQIAAQMrNKKLPMVDDLRDESDHenptrlvi 299
Cdd:PTZ00108 865 ---------TIERNPKGKFISKGIYEKvPDGTVEITELPIGKWTEDYKEFLESET-LKEKDVIVDYRDYSTA-------- 926
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 300 vprsNRVDM-----DQVMNHlFATTDLEK----SYRINL-NMIGLDGRPAVK---NLLEILSEWLVFRRDTVRRRLNYRL 366
Cdd:PTZ00108 927 ----NTVHFtvklnDGVLEQ-WEEEGIEKvfklKSTISTtNMVLFDENGKIKkysDALDILKEFYLVRLDLYKKRKEYLL 1001
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 367 EKVLKRLHILEGlLVAFLN--IDEVIEIIRNEDEPKPALMSRFGLTetqaeAILELKLRHLAKLEEMKIRGEQSELEKER 444
Cdd:PTZ00108 1002 GKLERELARLSN-KVRFIKhvINGELVITNAKKKDLVKELKKLGYV-----RFKDIIKKKSEKITAEEEEGAEEDDEADD 1075
|
490 500
....*....|....*....|.
gi 15833157 445 DQLQGILASERKMNNLLKKEL 465
Cdd:PTZ00108 1076 EDDEEELGAAVSYDYLLSMPI 1096
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
5-380 |
3.18e-14 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 76.67 E-value: 3.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 5 AERLALHEFTENAYLNYSMYvIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDvLGKYHpHGDSACYE 84
Cdd:PLN03128 650 GNGISYSDFINKELILFSQA-DLARSIPSMVDGLKPSQRKVLFACFKRNLKSEIKVAQLSGYVAE-HSAYH-HGEASLAS 726
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 85 AMVLMAQPF--SYRYPLVDGQGNWGAP-DDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVpNFDGTLQEPKMLPARL 161
Cdd:PLN03128 727 TIIGMAQDFvgSNNINLLTPSGQFGTRlQGGKDAASARYIFTRLSPITRALFPKDDDVLLNYL-NEDGQSIEPEWYCPII 805
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 162 PNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQpkTTLDQLLDIVQGpdypTEAEIITSRAeirkiyENGRGSVRM 241
Cdd:PLN03128 806 PMVLVNGSEGIGTGWSTFIPNYNPRDIIANIRRLLRG--EELEPMHPWYRG----FKGTITEVST------SRSGSYTVT 873
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 242 RAVWKKEDGAVVISALPHQVSGARVLEQIAAQMR--NKKLPMVDDLRDESDHENPTRLVIVPRSNrvdmdqvMNHLFAtT 319
Cdd:PLN03128 874 GIIEQIGDTTIRITELPVRKWTQDYKEFLEALLTgtKKKEPEIKDFKENHTDTTVHFTVTLSEEK-------MARALA-E 945
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 15833157 320 DLEKSYRI-------NLNMIGLDGRPA--------VKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLL 380
Cdd:PLN03128 946 GLEKKFKLsttistsNMHLFDKDGKIKkydspediLEEFFHLRLDLYVKRKEVLLENLEYELKKLDNKARFILAVV 1021
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
21-188 |
3.18e-11 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 67.19 E-value: 3.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 21 YSMYVIMdRALPFIGDGLKPVQRRIVYAMSELGLNASAKFkksARTVGDV--LGKYHpHGDSACYEAMVLMAQPF--SYR 96
Cdd:PLN03237 691 FSMADLQ-RSIPSMVDGLKPGQRKILFCSFKRNFVKEAKV---AQLSGYVseHSAYH-HGEQSLASTIIGMAQDFvgSNN 765
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 15833157 97 YPLVDGQGNWGA-PDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVpNFDGTLQEPKMLPARLPNILLNGTTGIAVG 175
Cdd:PLN03237 766 INLLLPNGQFGTrLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTG 844
|
170
....*....|...
gi 15833157 176 MATDIPPHNLREV 188
Cdd:PLN03237 845 WSTFIPNYNPRDI 857
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
641-675 |
3.70e-04 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 38.62 E-value: 3.70e-04
10 20 30
....*....|....*....|....*....|....*.
gi 15833157 641 DMLLAITQAGRMLMFPVSDLPQLSKG-KGNKIINIP 675
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGaKGVKGINLK 36
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
592-637 |
3.53e-03 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 35.93 E-value: 3.53e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 15833157 592 QKLLMASDAGYGFVCTFNDLVARNRA--GKALITLPENAHVMPPVVIE 637
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGakGVKGINLKEGDKVVSVLVVN 48
|
|
| SWIRM-assoc_1 |
pfam16495 |
SWIRM-associated region 1; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 ... |
402-447 |
8.34e-03 |
|
SWIRM-associated region 1; Much of the higher eukaryote SWI/SNF complex subunit SMARCC2 proteins is of low-complexity and or disordered. However, there are several short regions that are quite highly conserved. This is one of these regions. The function of the individual regions is not known.
Pssm-ID: 465142 [Multi-domain] Cd Length: 84 Bit Score: 35.96 E-value: 8.34e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 15833157 402 ALMSrfGLTETQAEAiLELKLRHLAKLEEMkIRGEQSELEKERDQL 447
Cdd:pfam16495 24 RLVA--LLVETQLKK-LELKLKQFEELEKL-LERERRQLERQRQQL 65
|
|
| |
