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Conserved domains on  [gi|1447699825|ref|NP_312707|]
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F0F1 ATP synthase subunit A [Escherichia coli O157:H7 str. Sakai]

Protein Classification

FoF1 ATP synthase subunit a( domain architecture ID 10012597)

FoF1 ATP synthase subunit a is part of the membrane proton channel of the F-type ATPase that produces ATP from ADP in the presence of a proton gradient across the membrane; it plays a direct role in the translocation of protons across the membrane

Gene Ontology:  GO:0045263|GO:0046933|GO:0005886
PubMed:  28001127

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 38-271 1.07e-75

F0F1 ATP synthase subunit A; Validated


:

Pssm-ID: 235617  Cd Length: 227  Bit Score: 229.68  E-value: 1.07e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  38 FWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNL 117
Cdd:PRK05815    9 FGGFNFDSLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGGKGKKFAPLAFTLFLFILLMNL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 118 MDLLPIdllpyiaehvlglpaLRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFnhWAFIPVNLIleg 197
Cdd:PRK05815   89 LGLIPY---------------LLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEFYLQPH--PLLLPIEII--- 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1447699825 198 vSLLSKPVSLGLRLFGNMYAGELIFILI-----AGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK05815  149 -SEFSRPISLSLRLFGNMLAGELILALIallggAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
 
Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 38-271 1.07e-75

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 229.68  E-value: 1.07e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  38 FWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNL 117
Cdd:PRK05815    9 FGGFNFDSLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGGKGKKFAPLAFTLFLFILLMNL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 118 MDLLPIdllpyiaehvlglpaLRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFnhWAFIPVNLIleg 197
Cdd:PRK05815   89 LGLIPY---------------LLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEFYLQPH--PLLLPIEII--- 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1447699825 198 vSLLSKPVSLGLRLFGNMYAGELIFILI-----AGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK05815  149 -SEFSRPISLSLRLFGNMLAGELILALIallggAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 44-270 1.73e-69

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 213.40  E-value: 1.73e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  44 DSMFFSVVLGLLFLVLFRSVAKKAtSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPi 123
Cdd:COG0356     1 DTVLMSWLAMLLLLLLFLLATRKL-KLVPGGLQNFVEMLVEFVRNQVKDTIGKKGRKFAPLLLTLFLFILVSNLLGLIP- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 124 dllpyiaehvlGLpalrVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFnhWAFIPVNLILEGVSLLSK 203
Cdd:COG0356    79 -----------GL----FPPTADINVTLALALIVFVLVHYYGIKKKGLGGYLKHLFFPPF--PWLAPLMLPIEIISELAR 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447699825 204 PVSLGLRLFGNMYAGELIFILIAGLLPWWS----QWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEE 270
Cdd:COG0356   142 PLSLSLRLFGNMFAGHIILLLLAGLAPFLLlgvlSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
63-265 3.49e-56

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 179.61  E-value: 3.49e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  63 VAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKS-KLIAPLALTIFVWVFLMNLMDLLPIdlLPYIAEhvlglpalrv 141
Cdd:pfam00119  18 ATRKTKKLVPGRLQNFVEMLVEFVDNIVKDNIGKKKgRKFFPLLLTLFFFILVSNLLGLIPK--SPGGFT---------- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 142 vPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLqPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELI 221
Cdd:pfam00119  86 -VTADINVTLALALIVFLLVHYYGIKKHGLGGYFKKLFV-PPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLL 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1447699825 222 FILIAGLLPW---------WSQWILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:pfam00119 164 LLLLAGLIFAllsagfllgVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 35-265 8.74e-31

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 114.23  E-value: 8.74e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  35 PATFWTINIDSMFFSVVLGLLFLVLFRSVAKKAtsgVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFL 114
Cdd:TIGR01131   7 ISPITLFSLTLLSLILLLSLLIFLISSSLSRWL---IPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 115 MNLMDLLPidllpyiaehvlglpaLRVVPSADVNVTLSMALGVFILILFYSIKMKGIGgFTKELTLQPFNHWaFIPVNLI 194
Cdd:TIGR01131  84 SNLLGLIP----------------YSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKG-FLAHLVPSGTPLP-LIPFLVI 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447699825 195 LEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQ-------WILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:TIGR01131 146 IETISYLARPISLSVRLFANISAGHLLLTLLSGLLFSLMSsaifallLLILVALIILEIFVAFIQAYVFTLLTCLYLN 223
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 99-265 3.13e-30

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 110.95  E-value: 3.13e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  99 KLIAPLALTIFVWVFLMNLMDLLPidllpyiaehvlglpaLRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKEL 178
Cdd:cd00310     2 KKYLPLLGTLFLFILFSNLLGLIP----------------YSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFL 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 179 TLQPFnhWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQW------ILNVPWAIFHILIITLQ 252
Cdd:cd00310    66 PPGTP--LPLAPLMVPIELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSvgllplLLPVALTLLELFVAFIQ 143

                         170
                  ....*....|...
gi 1447699825 253 AFIFMVLTIVYLS 265
Cdd:cd00310   144 AYVFTLLTAVYIS 156
 
Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 38-271 1.07e-75

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 229.68  E-value: 1.07e-75
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  38 FWTINIDSMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNL 117
Cdd:PRK05815    9 FGGFNFDSLLLSVLLGVLILLLFALVATRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGGKGKKFAPLAFTLFLFILLMNL 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 118 MDLLPIdllpyiaehvlglpaLRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFnhWAFIPVNLIleg 197
Cdd:PRK05815   89 LGLIPY---------------LLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEFYLQPH--PLLLPIEII--- 148

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1447699825 198 vSLLSKPVSLGLRLFGNMYAGELIFILI-----AGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK05815  149 -SEFSRPISLSLRLFGNMLAGELILALIallggAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 44-270 1.73e-69

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 213.40  E-value: 1.73e-69
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  44 DSMFFSVVLGLLFLVLFRSVAKKAtSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPi 123
Cdd:COG0356     1 DTVLMSWLAMLLLLLLFLLATRKL-KLVPGGLQNFVEMLVEFVRNQVKDTIGKKGRKFAPLLLTLFLFILVSNLLGLIP- 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 124 dllpyiaehvlGLpalrVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFnhWAFIPVNLILEGVSLLSK 203
Cdd:COG0356    79 -----------GL----FPPTADINVTLALALIVFVLVHYYGIKKKGLGGYLKHLFFPPF--PWLAPLMLPIEIISELAR 141

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447699825 204 PVSLGLRLFGNMYAGELIFILIAGLLPWWS----QWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEE 270
Cdd:COG0356   142 PLSLSLRLFGNMFAGHIILLLLAGLAPFLLlgvlSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
63-265 3.49e-56

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 179.61  E-value: 3.49e-56
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  63 VAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKS-KLIAPLALTIFVWVFLMNLMDLLPIdlLPYIAEhvlglpalrv 141
Cdd:pfam00119  18 ATRKTKKLVPGRLQNFVEMLVEFVDNIVKDNIGKKKgRKFFPLLLTLFFFILVSNLLGLIPK--SPGGFT---------- 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 142 vPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLqPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELI 221
Cdd:pfam00119  86 -VTADINVTLALALIVFLLVHYYGIKKHGLGGYFKKLFV-PPVPLPLVPLLLPIEIISEFARPVSLSLRLFGNMLAGHLL 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1447699825 222 FILIAGLLPW---------WSQWILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:pfam00119 164 LLLLAGLIFAllsagfllgVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 35-265 8.74e-31

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 114.23  E-value: 8.74e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  35 PATFWTINIDSMFFSVVLGLLFLVLFRSVAKKAtsgVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFL 114
Cdd:TIGR01131   7 ISPITLFSLTLLSLILLLSLLIFLISSSLSRWL---IPSRWQNLMESIYEFVLSIVKSQIGGKKGKFFPLIFTLFLFILI 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 115 MNLMDLLPidllpyiaehvlglpaLRVVPSADVNVTLSMALGVFILILFYSIKMKGIGgFTKELTLQPFNHWaFIPVNLI 194
Cdd:TIGR01131  84 SNLLGLIP----------------YSFTPTSHLSFTLGLALPLWLGLTISGFRKHPKG-FLAHLVPSGTPLP-LIPFLVI 145

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1447699825 195 LEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQ-------WILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:TIGR01131 146 IETISYLARPISLSVRLFANISAGHLLLTLLSGLLFSLMSsaifallLLILVALIILEIFVAFIQAYVFTLLTCLYLN 223
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 99-265 3.13e-30

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 110.95  E-value: 3.13e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  99 KLIAPLALTIFVWVFLMNLMDLLPidllpyiaehvlglpaLRVVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKEL 178
Cdd:cd00310     2 KKYLPLLGTLFLFILFSNLLGLIP----------------YSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFL 65

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 179 TLQPFnhWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLPWWSQW------ILNVPWAIFHILIITLQ 252
Cdd:cd00310    66 PPGTP--LPLAPLMVPIELISELIRPLSLSVRLFANMFAGHLLLALLSGLVPSLLSSvgllplLLPVALTLLELFVAFIQ 143

                         170
                  ....*....|...
gi 1447699825 253 AFIFMVLTIVYLS 265
Cdd:cd00310   144 AYVFTLLTAVYIS 156
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 61-271 2.91e-20

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 88.65  E-value: 2.91e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  61 RSVAKKATSGVPGKFQTAIELVIGFVNGSV--KDMYHGKSKLIaPLALTIFVWVFLMNLmdllpIDLLPYIAehvlglpa 138
Cdd:PRK13419  129 RKYKKMTKSQAPKGLANAMEALVEFIRLDVakSNIGHGYEKFL-PYLLTVFFFILVCNL-----LGLVPYGA-------- 194

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 139 lrvVPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQpfNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG 218
Cdd:PRK13419  195 ---TATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGG--THWSLWIIMIPIEFIGLFTKPFALTVRLFANMTAG 269

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1447699825 219 E-----LIFILIAgLLPWWSQWILNVPWAIF----HILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK13419  270 HivilsLIFISFI-LKSYIVAVAVSVPFAIFiyllELFVAFLQAYIFTMLSALFIGLATAHE 330
PRK13421 PRK13421
F0F1 ATP synthase subunit A; Provisional
 71-270 1.36e-16

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237383  Cd Length: 223  Bit Score: 76.27  E-value: 1.36e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  71 VPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPidllpyiaehvlGLPAlrvvPSADVNVT 150
Cdd:PRK13421   47 APGRLQSVLELVVTTIDAQIRDTMQTDPAPYRALIGTLFLFVLVANWSSLVP------------GVEP----PTAHLETD 110

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 151 LSMALGVFILILFYSIKMKGIGGFtkeltLQPFNH--WAFIPVNLilegVSLLSKPVSLGLRLFGNMYAGEL---IFILI 225
Cdd:PRK13421  111 AALALIVFLATIYYGVRARGVRGY-----LATFAEptWVMIPLNL----VEQLTRTFSLIVRLFGNVMSGVFvigIVLSL 181

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 1447699825 226 AGLLpwwsqwiLNVPWAIFHILIITLQAFIFMVLTIVYLSMASEE 270
Cdd:PRK13421  182 AGLL-------VPIPLMALDLLTGAVQAYIFAVLAMVFIGAAVSD 219
PRK13420 PRK13420
F0F1 ATP synthase subunit A; Provisional
 72-271 1.88e-16

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237382 [Multi-domain]  Cd Length: 226  Bit Score: 75.93  E-value: 1.88e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  72 PGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPidllpyiaehvlGLPAlrvvPSADVNVTL 151
Cdd:PRK13420   45 PGRFQVALEGVVSTIEDAIKEVLPRHARLVLPFVGTLWIFILVANLIGLIP------------GFHS----PTADLSVTA 108

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 152 SMALGVFILILFYSIKMKGIGGFTKE-LTLQPFnhwaFIPVNLILEgvslLSKPVSLGLRLFGNMYAGE---LIFILIAG 227
Cdd:PRK13420  109 ALALLVFFSVHWFGIRAEGLREYLKHyLSPSPF----LLPFHLISE----ITRTLALAVRLFGNIMSLElaaLLVLLVAG 180

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1447699825 228 LLpwwsqwiLNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK13420  181 FL-------VPVPILMLHIIEALVQAYIFGMLALIYIAGGIQAH 217
atpI CHL00046
ATP synthase CF0 A subunit
 71-263 5.80e-08

ATP synthase CF0 A subunit


Pssm-ID: 176987  Cd Length: 228  Bit Score: 52.24  E-value: 5.80e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  71 VPGKFQTAIELVIGFVNGSVKD-MYHGKSKLIAPLALTIFVWVFLMNLMD-LLPIDLLPyiaehvlgLPALRVV-PSADV 147
Cdd:CHL00046   50 IPTGGQNFFEYVLEFIRDLAKTqIGEEEYRPWVPFIGTMFLFIFVSNWSGaLLPWKLIE--------LPHGELAaPTNDI 121

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 148 NVTLSMALGVFILILFYSIKMKGIGGFTKELTLQPFnhwaFIPVNlILEGvslLSKPVSLGLRLFGNMYAGELIFILIAG 227
Cdd:CHL00046  122 NTTVALALLTSVAYFYAGLSKKGLGYFGKYIQPTPI----LLPIN-ILED---FTKPLSLSFRLFGNILADELVVAVLVS 193

                         170       180       190
                  ....*....|....*....|....*....|....*...
gi 1447699825 228 LLPwwsqwiLNVPWAIFHILIIT--LQAFIFMVLTIVY 263
Cdd:CHL00046  194 LVP------LVVPIPVMFLGLFTsgIQALIFATLAAAY 225
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 72-265 1.98e-06

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 47.72  E-value: 1.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  72 PGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPidllpyiaeHVLGlpalrvvPSADVNVTL 151
Cdd:MTH00176   42 PSKLQVFMLMFSTFLPEMILRSNGSYILGSASIIISLFILVMSLNLSGLIP---------YVFT-------STSHLVITL 105

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 152 SMALGVFILILFYSIKMKGIGGFTKELTLQpfNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIA----- 226
Cdd:MTH00176  106 SLALPLWLGVILSGFINNFYSRLSHLVPQG--TPPLLNPFLVLIELVSLLIRPLTLAVRLAANLSAGHLLLGLLGaamwg 183

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 1447699825 227 ----GLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:MTH00176  184 llpvSPLIGFLLLIVQILYFMFEIAVCMIQAYVFTLLLSLYLD 226
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 71-264 3.01e-06

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 46.96  E-value: 3.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  71 VPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPIDLLPyiaehvlglpalrvvpsaDVNVT 150
Cdd:MTH00172   41 IPKRWQSIIEIIYNHFHGVVKDNLGNEGLKYFPFIISLFFFIVFLNLLGLFPYVFTP------------------TTHIV 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 151 LSMALGVFILIlfySIKMKGIGGFTKEL--TLQPFNH-WAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAG 227
Cdd:MTH00172  103 VTLGLSFSIII---GVTLAGFWRFKWDFfsILMPSGApLGLAPLLVLIETVSYISRAISLGVRLAANLSAGHLLFAILAG 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 1447699825 228 LLpwWSQWILNVPWAIFHILI---ITL--------QAFIFMVLTIVYL 264
Cdd:MTH00172  180 FG--FNMLCASGFLSLFPLLImvfITLleiavaviQAYVFCLLTTIYL 225
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 71-265 1.06e-05

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 45.38  E-value: 1.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  71 VPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLmdllpIDLLPYIaehvlglpalrVVPSADVNVT 150
Cdd:MTH00175   52 IPNRWQSIMELIYLNIRSVVHDNLGKSGQKYFPFILSLFLFIAILNI-----LGLFPYV-----------FTPTAHIIIT 115

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 151 LSMALGVFILIL----------FYSIKMKGiggfTKELTLQPFNhwafipvnLILEGVSLLSKPVSLGLRLFGNMYAGEL 220
Cdd:MTH00175  116 FGLSLSIIIAVTllgfltfkwnFLSILMPG----GAPLVLAPFL--------VLIETLSYLIRAISLGVRLAANISAGHL 183

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1447699825 221 IFILIAG-----------LLPWWSQWILnVPWAIFHILIITLQAFIFMVLTIVYLS 265
Cdd:MTH00175  184 LFAILSGfafnmlsngliILSLFPMLIM-IFITLLEMAVAVIQAYVFCLLTTIYLG 238
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 71-271 1.76e-05

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 45.27  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  71 VPGKFQTAIELVIGFVNGSVKD-MYHGKSKLIAPLALTIFVWVFLMNLMDLLP-IDLLPYIAEHVLGLPALRV------- 141
Cdd:PRK13417  126 VQSRFANTVEVFVNFLRKDIVDeSMHGHGHSYYHYIFTLFFFILFCNLMGLVPsVGELTVVASDYGGLVALGVmdhtpha 205

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 142 -----------VPSADVNVTLSMALGVFILILFYSIKMKGIGGFTKELTLQ-PFNHWAFI-PVNLIlegVSLLSKPVSLG 208
Cdd:PRK13417  206 lptfakvwsgiTVTGDISVTMTLALLTMFLIYGAGFSYQGPKFIWHSVPNGvPLLLYPIMwPLEFI---VSPMAKTFALT 282

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1447699825 209 LRLFGNMYAGELIFILIAGLLPWWSQWILnVPWAI--------FHILIITLQAFIFMVLTIVYLSMASEEH 271
Cdd:PRK13417  283 VRLLANMTAGHVIILALMGFIFQFQSWGI-VPVSVigsgliyvLEIFVAFLQAYIFVLLTSLFVGLSMHRH 352
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 71-265 6.90e-05

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 42.85  E-value: 6.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825  71 VPGKFQTAIELVIGFVNGSVKDMYHGKSKLIAPLALTIFVWVFLMNLMDLLPidllpYIaehvlglpalrVVPSADVNVT 150
Cdd:MTH00157   38 IPSRYNILWNKILKTLHKEFKTLLGPKNKGSTLIFISLFSFILFNNFLGLFP-----YI-----------FTSTSHLSLT 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 151 LSMALGVFILILFYSIKMKgiggftkelTLQPFNHW-------AFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFI 223
Cdd:MTH00157  102 LSLALPLWLSFMLFGWINN---------TNHMFAHLvpqgtppILMPFMVLIETISNLIRPGTLAVRLAANMIAGHLLLT 172

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*....
gi 1447699825 224 LIAGLLPWWSQWILNVPWaIFHILIITL-------QAFIFMVLTIVYLS 265
Cdd:MTH00157  173 LLGNTGPSLSSMILSILI-LIQILLLILesavaiiQSYVFSVLSTLYSS 220
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 185-271 1.03e-03

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 39.46  E-value: 1.03e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 185 HWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLLP---WWSQW-------ILNVPWAIFHILIITLQAF 254
Cdd:MTH00173  137 PAGLNPFLVLIETVSILIRPLTLTVRLLANISAGHIVLTLIGNYLSsslFSSSVvslllvlLIQVGYFIFEVAVMLIQAY 216

                          90
                  ....*....|....*..
gi 1447699825 255 IFMVLTIVYlsmaSEEH 271
Cdd:MTH00173  217 IFTLLIKLY----SDEH 229
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 187-271 4.04e-03

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 38.00  E-value: 4.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1447699825 187 AFIPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIAGLL-PWWSQWILNVPWAIFHILIIT---------LQAFIF 256
Cdd:MTH00174  158 ALAPLLTIIETLSYISRAISLGVRLAANISSGHLLFSIIASFAwKMINTGILIGSFVPFAILIFVtilemavaiIQAYVF 237

                          90
                  ....*....|....*
gi 1447699825 257 MVLTIVYLSMASEEH 271
Cdd:MTH00174  238 TLLTIVYLRDTVELH 252
ATP6 MTH00132
ATP synthase F0 subunit 6; Provisional
 189-226 5.99e-03

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177190  Cd Length: 227  Bit Score: 37.16  E-value: 5.99e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1447699825 189 IPVNLILEGVSLLSKPVSLGLRLFGNMYAGELIFILIA 226
Cdd:MTH00132  139 IPVLIIIETISLFIRPLALGVRLTANLTAGHLLIQLIA 176
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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