|
Name |
Accession |
Description |
Interval |
E-value |
| PQQ_membr_DH |
TIGR03074 |
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; This protein ... |
33-792 |
0e+00 |
|
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Members of this family have several predicted transmembrane helices in the N-terminal region, and include the quinoprotein glucose dehydrogenase (EC 1.1.5.2) of Escherichia coli and the quinate/shikimate dehydrogenase of Acinetobacter sp. ADP1 (EC 1.1.99.25). Sequences closely related except for the absense of the N-terminal hydrophobic region, scoring in the gray zone between the trusted and noise cutoffs, include PQQ-dependent glycerol (EC 1.1.99.22) and and other polyol (sugar alcohol) dehydrogenases.
Pssm-ID: 274418 [Multi-domain] Cd Length: 764 Bit Score: 1237.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 33 WLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWR- 111
Cdd:TIGR03074 1 WLVALGGSWYYLLAGLALLLSAWLLFRRRPAGLWLYAALLLGTLIWALWEVGLDFWPLIPRLGLIAVLGLWLLLPWVRRp 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 112 RLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAISP-VADQDWPAYGRNQEGQRFSPLKQINADN 190
Cdd:TIGR03074 81 RSVGPARRGAGALAGVLAVAVLAALASMFTDPHPIVGALDTEVPATAAAAPaVPAGDWAAYGRTQAGQRYSPLDQINPDN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 191 VHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSY 270
Cdd:TIGR03074 161 VGNLKVAWTYHTGDLKTPDDPGEATFQATPLKVGDTLYLCTPHNKVIALDAATGKEKWKFDPKLKTEADRQHQTCRGVSY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 271 HEAKAETASP---EVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIV 347
Cdd:TIGR03074 241 YDAPAAAAGPagpAAPADCARRIILPTSDARLIALDADTGKLCEDFGNNGTVDLTAGMGPTPPGYYYPTSPPLVAGTTVV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 348 MAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDI 427
Cdd:TIGR03074 321 IGGRVADNYSTDEPSGVIRAFDVNTGALVWAWDPGNPDPTAPPAPGETYTRNSPNSWSVASYDEKLGLVYLPMGNQTPDQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 428 WGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV-NGQKVPVIYAPAKTGNIFVLDRRNGE 506
Cdd:TIGR03074 401 WGGDRTPADEKYSSSLVALDATTGKERWVFQTVHHDLWDMDVPAQPSLVDLPKaDGTTVPALVAPTKQGQIYVLDRRTGE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 507 LVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPtKDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGN 586
Cdd:TIGR03074 481 PIVPVEEVPVPQGAVPGERYSPTQPFSVLTFGP-PTLTESDMWGATPFDQLACRIQFKSLRYEGLYTPPSEQGSLVFPGN 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 587 LGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNpmEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQ 666
Cdd:TIGR03074 560 LGGFNWGGVAVDPTRQVMFVNPMRLPFVSQLVPRAPGD--EAPSGAKGKGTEMGLNPNKGTPYAVNMNPFLSPLGIPCQA 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 667 PAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSNGEKLWQ 746
Cdd:TIGR03074 638 PPWGYMAAIDLKTGKVVWQHPNGTVRDTGPMGIPMPLPIPIGVPTLGGPLATAGGLVFIGATQDNYLRAYDLSTGKELWE 717
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 16128117 747 GRLPAGGQATPMTY-EVNGKQYVVISAGGHGSFGTKMGDYIVAYALP 792
Cdd:TIGR03074 718 ARLPAGGQATPMTYmGKDGKQYVVIVAGGHGSSGTKRGDYVIAYALP 764
|
|
| PQQ_mGDH |
cd10280 |
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ... |
168-791 |
0e+00 |
|
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199838 [Multi-domain] Cd Length: 616 Bit Score: 940.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 168 WPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPnDPGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEK 247
Cdd:cd10280 1 WPAYGGDPGGTRYSPLDQITPDNVGKLKVAWTYHTGDLPGP-DGNEGTFEATPLKVGGTLYLCTPHNRVIALDAATGKEL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 248 WHYDPELKTNESFQHVTCRGVSYHEAKAETASpevmadCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPD 327
Cdd:cd10280 80 WRFDPKAGADAAPGHQTCRGVSYWEDGAAAAA------CARRIFFGTGDARLIALDARTGKPCPDFGDNGVVDLREGLGR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 328 TKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEH-TFTFNSPNSWAP 406
Cdd:cd10280 154 VKPGFYSSTSPPTVYGDLVIVGSAVADNQAVDAPSGVIRAFDVRTGKLVWAFDTIPPPGEAGPDTAGaWYTRGGPNVWAG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 407 AAYDAKLDLVYLPMGVTTPDIWGGNRtPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVP 486
Cdd:cd10280 234 MSADEKLGLVYLPTGSATPDFYGGDR-PGDNLFANSLVALDAATGKRRWHFQTVHHDLWDYDLPAQPTLVDVPRDGKTVP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 487 VIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSF-RPTKDLSGADMWGATMFDQLVCRVMFHQ 565
Cdd:cd10280 313 AVAQPTKQGFVFVLDRRTGKPLWPVEERPVPQGDVPGERTSPTQPFPTLPPpFARQGLTEDDMWGATPFDQLACRIQFRS 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 566 MRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQY 645
Cdd:cd10280 393 LRYEGLFTPPSLDGTLIFPGNDGGANWGGAAVDPERGILYVNSNRLPFVIQLVPRAPGDPAGVAGGGEGGGGGGGPSPQA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 646 GVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSmpFPMPVPVPFNMGMPMLGGPISTAGNVLFI 725
Cdd:cd10280 473 GTPYGVGRGRFLSPLGLPCQAPPWGTLTAIDLNTGKILWQVPLGTVPDL--GPKGIPLPIPTGTPNLGGPVVTAGGLVFI 550
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16128117 726 AATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYAL 791
Cdd:cd10280 551 AATQDNYLRAFDKATGKELWEARLPAGGQATPMTYEVDGKQYVVIAAGGHGSLGTKRGDSVIAYAL 616
|
|
| Gcd |
COG4993 |
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism]; |
164-792 |
0e+00 |
|
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
Pssm-ID: 444017 [Multi-domain] Cd Length: 515 Bit Score: 659.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 164 ADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKqpndpgEITNEVTPIKVGDTLYLCTAHQRLFALDAAS 243
Cdd:COG4993 1 DPGDWLAYGGDYAGQRYSPLDQINPDNVKKLKVAWTFSTGDLP------ERGHEATPLVVDGVLYVCTPHNRVFALDAAT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 244 GKEKWHYDPELKTNESFQHVTCRGVSYHEakaetaspevmadcpRRIILPVNDGRLIAINAENGKLCETfaNKgvlnlqs 323
Cdd:COG4993 75 GKELWRYDPKLPDDAACCDVVNRGVAYYD---------------GRIFLGTLDGRLVALDAKTGKVCWD--VK------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 324 nMPDTKPGlYEPTSPPIITDKTIVMAGSVTDNfstrETSGVIRGFDVNTGELLWAFD--PGAKDP-NAIPSDEHTFTFNS 400
Cdd:COG4993 131 -VGDPKKG-YTITSAPLVVKDKVIVGGSGGEF----GPRGVVRAYDARTGKLVWRFDtiPDPGEPgAETWPPGDTWKRGG 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 401 PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRtPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV 480
Cdd:COG4993 205 GNVWGTMSYDPELGLVYLPTGNPAPDWNGGQR-PGDNLYSSSIVALDADTGELKWHYQTVPHDLWDYDGPNEPILVDLPV 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 481 NGQKVPVIYAPAKTGNIFVLDRRNGELVVpapekpvpqgaakgdyvtpTQPFSE-LSFRptkdlSGADMWGATMFdqlvc 559
Cdd:COG4993 284 DGKTRKALVQATKNGFIYVLDRETGEPLV-------------------TQPFVKpPNWA-----TEIDMWGATPI----- 334
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 560 rvmfhqmryegiFTPPSEQG--TLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRgpgnpmeqpkdakgtgt 637
Cdd:COG4993 335 ------------QTPPSLDGktTLICPGALGGKNWGPAAYDPETGLLYVPANELCMDYELVPR----------------- 385
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 638 esgiQPQYGVPY-GVTLNPFlspfglPCKQPAWGYISALDLKTNEVVWKKRigtpqdsmpfpmpvpvpfnMGMPMLGGPI 716
Cdd:COG4993 386 ----EYQAGAPYlGATLTMY------PCPAPPWGTLTAIDLNTGKIVWQVP-------------------LGFPNWGGPL 436
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 717 STAGNVLFIaATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFG----TKMGDYIVAYALP 792
Cdd:COG4993 437 ATAGGLVFI-GTLDGYLRAFDAKTGKELWKFRLPSGGQATPMTYEVDGKQYVAVAAGGGGWLGlglyTPQGDYLIAFALP 515
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
225-253 |
1.11e-05 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 42.95 E-value: 1.11e-05
10 20
....*....|....*....|....*....
gi 16128117 225 DTLYLCTAHQRLFALDAASGKEKWHYDPE 253
Cdd:pfam01011 1 GTVYLGSDDGYLYALDAETGKVLWSFKTG 29
|
|
| PQQ |
smart00564 |
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ... |
220-251 |
2.97e-03 |
|
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.
Pssm-ID: 128836 [Multi-domain] Cd Length: 33 Bit Score: 35.97 E-value: 2.97e-03
10 20 30
....*....|....*....|....*....|...
gi 16128117 220 PIKVGD-TLYLCTAHQRLFALDAASGKEKWHYD 251
Cdd:smart00564 1 PVVLSDgTVYVGSTDGTLYALDAKTGEILWTYK 33
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PQQ_membr_DH |
TIGR03074 |
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; This protein ... |
33-792 |
0e+00 |
|
membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; This protein family has a phylogenetic distribution very similar to that coenzyme PQQ biosynthesis enzymes, as shown by partial phylogenetic profiling. Members of this family have several predicted transmembrane helices in the N-terminal region, and include the quinoprotein glucose dehydrogenase (EC 1.1.5.2) of Escherichia coli and the quinate/shikimate dehydrogenase of Acinetobacter sp. ADP1 (EC 1.1.99.25). Sequences closely related except for the absense of the N-terminal hydrophobic region, scoring in the gray zone between the trusted and noise cutoffs, include PQQ-dependent glycerol (EC 1.1.99.22) and and other polyol (sugar alcohol) dehydrogenases.
Pssm-ID: 274418 [Multi-domain] Cd Length: 764 Bit Score: 1237.96 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 33 WLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGIWLILPFVWR- 111
Cdd:TIGR03074 1 WLVALGGSWYYLLAGLALLLSAWLLFRRRPAGLWLYAALLLGTLIWALWEVGLDFWPLIPRLGLIAVLGLWLLLPWVRRp 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 112 RLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAISP-VADQDWPAYGRNQEGQRFSPLKQINADN 190
Cdd:TIGR03074 81 RSVGPARRGAGALAGVLAVAVLAALASMFTDPHPIVGALDTEVPATAAAAPaVPAGDWAAYGRTQAGQRYSPLDQINPDN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 191 VHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSY 270
Cdd:TIGR03074 161 VGNLKVAWTYHTGDLKTPDDPGEATFQATPLKVGDTLYLCTPHNKVIALDAATGKEKWKFDPKLKTEADRQHQTCRGVSY 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 271 HEAKAETASP---EVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYEPTSPPIITDKTIV 347
Cdd:TIGR03074 241 YDAPAAAAGPagpAAPADCARRIILPTSDARLIALDADTGKLCEDFGNNGTVDLTAGMGPTPPGYYYPTSPPLVAGTTVV 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 348 MAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDI 427
Cdd:TIGR03074 321 IGGRVADNYSTDEPSGVIRAFDVNTGALVWAWDPGNPDPTAPPAPGETYTRNSPNSWSVASYDEKLGLVYLPMGNQTPDQ 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 428 WGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV-NGQKVPVIYAPAKTGNIFVLDRRNGE 506
Cdd:TIGR03074 401 WGGDRTPADEKYSSSLVALDATTGKERWVFQTVHHDLWDMDVPAQPSLVDLPKaDGTTVPALVAPTKQGQIYVLDRRTGE 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 507 LVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPtKDLSGADMWGATMFDQLVCRVMFHQMRYEGIFTPPSEQGTLVFPGN 586
Cdd:TIGR03074 481 PIVPVEEVPVPQGAVPGERYSPTQPFSVLTFGP-PTLTESDMWGATPFDQLACRIQFKSLRYEGLYTPPSEQGSLVFPGN 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 587 LGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNpmEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQ 666
Cdd:TIGR03074 560 LGGFNWGGVAVDPTRQVMFVNPMRLPFVSQLVPRAPGD--EAPSGAKGKGTEMGLNPNKGTPYAVNMNPFLSPLGIPCQA 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 667 PAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSNGEKLWQ 746
Cdd:TIGR03074 638 PPWGYMAAIDLKTGKVVWQHPNGTVRDTGPMGIPMPLPIPIGVPTLGGPLATAGGLVFIGATQDNYLRAYDLSTGKELWE 717
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 16128117 747 GRLPAGGQATPMTY-EVNGKQYVVISAGGHGSFGTKMGDYIVAYALP 792
Cdd:TIGR03074 718 ARLPAGGQATPMTYmGKDGKQYVVIVAGGHGSSGTKRGDYVIAYALP 764
|
|
| PQQ_mGDH |
cd10280 |
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes ... |
168-791 |
0e+00 |
|
Membrane-bound PQQ-dependent glucose dehydrogenase; This bacterial subfamily of enzymes belongs to the dehydrogenase family with pyrroloquinoline quinone (PQQ) as cofactor, and is the only subfamily that is bound to the membrane. Glucose dehydrogenase converts D-glucose to D-glucono-1,5-lactone in a reaction that is coupled with the respiratory chain in the periplasmic oxidation of sugars and alcohols in gram-negative bacteria. Ubiquinone functions as the electron acceptor. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199838 [Multi-domain] Cd Length: 616 Bit Score: 940.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 168 WPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPnDPGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEK 247
Cdd:cd10280 1 WPAYGGDPGGTRYSPLDQITPDNVGKLKVAWTYHTGDLPGP-DGNEGTFEATPLKVGGTLYLCTPHNRVIALDAATGKEL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 248 WHYDPELKTNESFQHVTCRGVSYHEAKAETASpevmadCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPD 327
Cdd:cd10280 80 WRFDPKAGADAAPGHQTCRGVSYWEDGAAAAA------CARRIFFGTGDARLIALDARTGKPCPDFGDNGVVDLREGLGR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 328 TKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEH-TFTFNSPNSWAP 406
Cdd:cd10280 154 VKPGFYSSTSPPTVYGDLVIVGSAVADNQAVDAPSGVIRAFDVRTGKLVWAFDTIPPPGEAGPDTAGaWYTRGGPNVWAG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 407 AAYDAKLDLVYLPMGVTTPDIWGGNRtPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVP 486
Cdd:cd10280 234 MSADEKLGLVYLPTGSATPDFYGGDR-PGDNLFANSLVALDAATGKRRWHFQTVHHDLWDYDLPAQPTLVDVPRDGKTVP 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 487 VIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSF-RPTKDLSGADMWGATMFDQLVCRVMFHQ 565
Cdd:cd10280 313 AVAQPTKQGFVFVLDRRTGKPLWPVEERPVPQGDVPGERTSPTQPFPTLPPpFARQGLTEDDMWGATPFDQLACRIQFRS 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 566 MRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESGIQPQY 645
Cdd:cd10280 393 LRYEGLFTPPSLDGTLIFPGNDGGANWGGAAVDPERGILYVNSNRLPFVIQLVPRAPGDPAGVAGGGEGGGGGGGPSPQA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 646 GVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSmpFPMPVPVPFNMGMPMLGGPISTAGNVLFI 725
Cdd:cd10280 473 GTPYGVGRGRFLSPLGLPCQAPPWGTLTAIDLNTGKILWQVPLGTVPDL--GPKGIPLPIPTGTPNLGGPVVTAGGLVFI 550
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16128117 726 AATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYAL 791
Cdd:cd10280 551 AATQDNYLRAFDKATGKELWEARLPAGGQATPMTYEVDGKQYVVIAAGGHGSLGTKRGDSVIAYAL 616
|
|
| Gcd |
COG4993 |
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism]; |
164-792 |
0e+00 |
|
Glucose dehydrogenase, PQQ-dependent [Carbohydrate transport and metabolism];
Pssm-ID: 444017 [Multi-domain] Cd Length: 515 Bit Score: 659.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 164 ADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKqpndpgEITNEVTPIKVGDTLYLCTAHQRLFALDAAS 243
Cdd:COG4993 1 DPGDWLAYGGDYAGQRYSPLDQINPDNVKKLKVAWTFSTGDLP------ERGHEATPLVVDGVLYVCTPHNRVFALDAAT 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 244 GKEKWHYDPELKTNESFQHVTCRGVSYHEakaetaspevmadcpRRIILPVNDGRLIAINAENGKLCETfaNKgvlnlqs 323
Cdd:COG4993 75 GKELWRYDPKLPDDAACCDVVNRGVAYYD---------------GRIFLGTLDGRLVALDAKTGKVCWD--VK------- 130
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 324 nMPDTKPGlYEPTSPPIITDKTIVMAGSVTDNfstrETSGVIRGFDVNTGELLWAFD--PGAKDP-NAIPSDEHTFTFNS 400
Cdd:COG4993 131 -VGDPKKG-YTITSAPLVVKDKVIVGGSGGEF----GPRGVVRAYDARTGKLVWRFDtiPDPGEPgAETWPPGDTWKRGG 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 401 PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRtPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV 480
Cdd:COG4993 205 GNVWGTMSYDPELGLVYLPTGNPAPDWNGGQR-PGDNLYSSSIVALDADTGELKWHYQTVPHDLWDYDGPNEPILVDLPV 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 481 NGQKVPVIYAPAKTGNIFVLDRRNGELVVpapekpvpqgaakgdyvtpTQPFSE-LSFRptkdlSGADMWGATMFdqlvc 559
Cdd:COG4993 284 DGKTRKALVQATKNGFIYVLDRETGEPLV-------------------TQPFVKpPNWA-----TEIDMWGATPI----- 334
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 560 rvmfhqmryegiFTPPSEQG--TLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRgpgnpmeqpkdakgtgt 637
Cdd:COG4993 335 ------------QTPPSLDGktTLICPGALGGKNWGPAAYDPETGLLYVPANELCMDYELVPR----------------- 385
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 638 esgiQPQYGVPY-GVTLNPFlspfglPCKQPAWGYISALDLKTNEVVWKKRigtpqdsmpfpmpvpvpfnMGMPMLGGPI 716
Cdd:COG4993 386 ----EYQAGAPYlGATLTMY------PCPAPPWGTLTAIDLNTGKIVWQVP-------------------LGFPNWGGPL 436
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 717 STAGNVLFIaATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFG----TKMGDYIVAYALP 792
Cdd:COG4993 437 ATAGGLVFI-GTLDGYLRAFDAKTGKELWKFRLPSGGQATPMTYEVDGKQYVAVAAGGGGWLGlglyTPQGDYLIAFALP 515
|
|
| PQQ_DH_like |
cd00216 |
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases ... |
188-790 |
6.56e-166 |
|
PQQ-dependent dehydrogenases and related proteins; This family is composed of dehydrogenases with pyrroloquinoline quinone (PQQ) as a cofactor, such as ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller, and the family also includes distantly related proteins which are not enzymatically active and do not bind PQQ.
Pssm-ID: 199833 [Multi-domain] Cd Length: 434 Bit Score: 486.73 E-value: 6.56e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 188 ADNVHNLKEAWVFRTGDVkqpndpGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTN--ESFQHVTC 265
Cdd:cd00216 1 ADNVFQLTPAWSFSTGDG------GNRGSELTPIVVDGVMYATTSFSRVFALDADDGKEIWSYDPALKDGwfEACCDLVN 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 266 RGVSYHeakaetaspevmadcPRRIILPVNDGRLIAINAENGKLCETFANKGVLnlqsnmpdtkpGLYEPTSPPIITDkT 345
Cdd:cd00216 75 RGVAVW---------------GGKVYIGVLDGRVYALNAETGKVAWKVKNADVL-----------GGYTATSAPVVVD-G 127
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 346 IVMAGSVTDNFstrETSGVIRGFDVNTGELLWAFDPGAKDPNAIP-------------SDEHTFTFNSPNSWAPAAYDAK 412
Cdd:cd00216 128 LVIIGSSGDEF---GVRGYLTAYDVATGEEKWRFYLVMPDPNLLPgkdstvtdrntptGDEHTWTSGGGTGWSSAAYDAE 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 413 LDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPA 492
Cdd:cd00216 205 LNLIYVGGGNPTPWNWGGNRTPGDNLYTSSIVAVNADTGEMKWQYQTTPHDAWDYDGDNTPVLADIKVKGKKVKVLFAPA 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 493 KTGNIFVLDRRNGELVVPAPEKPvpqgaakgdyvtptqpfselsfrptkdlsgadmwgatmfdqlvcrvmfhqmryegif 572
Cdd:cd00216 285 KNGNFYVLDRRNGELVSARPLVP--------------------------------------------------------- 307
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 573 tppseqgtlvfpgnlgmfewggISVDPNREVAIANPMalpfvskliprgpgnpmeqpkdakgtgtesgiqpqygvpygvt 652
Cdd:cd00216 308 ----------------------DSYDPDRELFYVPAN------------------------------------------- 322
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 653 lnpflspfglpckqpawGYISALDLKTNEVVWKKRIgtpqdsmpfpmpvpvpfnmGMPMLGGPISTAGNVLFIaATADNY 732
Cdd:cd00216 323 -----------------GRIMALDPVTGVVVWEKSE-------------------LHPLLGGPLSTAGNLVFV-GTSDGY 365
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16128117 733 LRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSF-----------GTKMGDYIVAYA 790
Cdd:cd00216 366 LKAYNADTGEKLWQQKVPSGFQAEPVTYEVDGEQYVLIQAGGGGAFplwggmadltrGTQMGGTVVVYK 434
|
|
| PQQ_ADH_I |
cd10277 |
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); ... |
164-773 |
2.42e-77 |
|
Ethanol dehydrogenase, a bacterial quinoprotein (PQQ-dependent type I alcohol dehydrogenase); This bacterial family of homodimeric ethanol dehydrogenases utilize pyrroloquinoline quinone (PQQ) as a cofactor. It represents proteins whose expression may be induced by ethanol, and which are similar to quinoprotein methanol dehydrogenases, but have higher specificities for ethanol and other primary and secondary alcohols. Dehydrogenases with PQQ cofactors, such as ethanol, methanol, and membrane-bound glucose dehydrogenases, form an 8-bladed beta-propeller.
Pssm-ID: 199835 [Multi-domain] Cd Length: 529 Bit Score: 259.54 E-value: 2.42e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 164 ADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQpndpGEitnEVTPIKVGDTLYLCTAHQRLFALDAAS 243
Cdd:cd10277 7 ETGNWLTYGRGYNGQRYSPLKQINTDNVKNLVPAWSFSFGGKQR----GQ---ESQPIVNDGVMYVTTSYNRVFAIDAKT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 244 GKEKWHYDPELKTNESFQ-HVTCRGVSYHEAKaetaspevmadcprrIILPVNDGRLIAINAENGKLCetfankgvlnLQ 322
Cdd:cd10277 80 GKELWKYKHRLPEDIRPCcDVVNRGVALYGDK---------------VYFGTLDAHLVALDAKTGKVV----------WK 134
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 323 SNMPDTKPGlYEPTSPPIITdKTIVMAGSVTDNFSTRetsGVIRGFDVNTGELLWAF-------DPGAKDPNaiPSDEHT 395
Cdd:cd10277 135 KKVADYKAG-YSMTLAPLVV-KGKVIVGVSGGEFGVR---GFIAALDAETGKEVWRTytvpgpgEPGSTDTW--PGDAWK 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 396 FTFNSPnsWAPAAYDAKLDLVYlpMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTL 475
Cdd:cd10277 208 TGGGAT--WLTGTYDPETNLLY--WGVGNPAPWNGDLRPGDNLYTSSVLALDPDTGKIKWHYQYTPNDTWDYDGVNEPVL 283
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 476 ADITVNGQKVPVIYAPAKTGNIFVLDRRNGELVvpapekpvpqgaakgdYVTptqPFSelsfrptKDLSGADMWGATmfd 555
Cdd:cd10277 284 FDYTKNGKPVKALVHADRNGFFYVLDRTNGKLI----------------WAT---PFV-------KKITWASIDLKT--- 334
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 556 qlvCRVMFHQMryegifTPPSEQGTLVF--PGNLGMFEWGGISVDPNREVAIAnpmalpfvskliprgPGNPMeqpkdak 633
Cdd:cd10277 335 ---GRPIYDED------KVPPKKGKTVDfcPSFLGGKNWPPMAYSPDTGLFYV---------------PANHW------- 383
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 634 gTGTESGIQPQY--GVPY---GVTLNPFLSPFglpckqpaWGYISALDLKTNEVVWKKRIGTpqdsmpfpmpvpvpfnmg 708
Cdd:cd10277 384 -CMDLTGEPVSYkkGAAYlgaGFTIKPPFEDH--------IGELQAIDPTTGKKVWEHKTPL------------------ 436
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128117 709 mPMLGGPISTAGNVLFiAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAG 773
Cdd:cd10277 437 -PLWGGVLTTAGGLVF-TGTPDGYFRAFDAKTGKELWEFQTGSGIIGPPVTWEVDGKQYVAVLSG 499
|
|
| PQQ_ADH_II |
cd10279 |
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of ... |
167-789 |
3.03e-72 |
|
PQQ_like domain of the quinohemoprotein alcohol dehydrogenase (type II); This family of monomeric and soluble type II alcohol dehydrogenases utilizes pyrroloquinoline quinone (PQQ) as a cofactor and is related to ethanol, methanol, and membrane-bound glucose dehydrogenases. The alignment model contains an 8-bladed beta-propeller.
Pssm-ID: 199837 [Multi-domain] Cd Length: 549 Bit Score: 246.40 E-value: 3.03e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 167 DWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTgdvkqPNDPGEitnEVTPIKVGDTLYLCTAHQRLFALDAASGKE 246
Cdd:cd10279 2 NWLSYGRDYDEQRFSPLTQINRSNVGQLGLAWYFDL-----DTNRGQ---EATPLVVDGVMYVSGPWSVVYALDARTGKL 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 247 KWHYDPELKTnESFQHVTC----RGVSYHEAKaetaspevmadcprrIILPVNDGRLIAINAENGKLC---ETFankgvl 319
Cdd:cd10279 74 LWQYDPEVDR-ESGRKACCdvvnRGVAVWDGK---------------VFVGTLDGRLIALDAKTGKEVwsvDTI------ 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 320 nlqsnmPDTKPglYEPTSPPIITdKTIVMAGSVTDNFSTRetsGVIRGFDVNTGELLWAFD--PGA-KDPNAIPSDEHTF 396
Cdd:cd10279 132 ------DPRKP--YTITGAPRVA-KGKVVIGNGGAEFGVR---GYVSAYDAETGKLVWRFYtvPGNpAKPFEHASLEAAA 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 397 TFNSPNSWAPA----------AYDAKLDLVYLPMGVTTPdiWG-GNRTPEQ--ERYASSILALNATTGKLAWSYQTVHHD 463
Cdd:cd10279 200 ATWWTGEWWRTggggtvwdsiTYDPELDLLYIGTGNGSP--WNrKVRSPGGgdNLFLSSIVALDADTGRYKWHYQTTPGD 277
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 464 LWDMDlPAQP-TLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELVvpAPEKPVPQGAAKG-DYVTPtqpfselsfRPtk 541
Cdd:cd10279 278 TWDYT-ATQPiILADLEIDGKPRKVLMHAPKNGFFYVLDRATGKLL--SAEPFVPVNWATGiDLKTG---------RP-- 343
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 542 dlsgadmwgatmfdqlvcrVMFHQMRYEgiftppsEQGTLVFPGNLGMFEWGGISVDPN-REVAI-ANPMALPFvsklip 619
Cdd:cd10279 344 -------------------IENPEARYT-------KGPKLVFPGPLGAHNWHPMSYNPDtGLVYIpAQEIPAVY------ 391
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 620 rgpgnpmeqpKDAKGTGTESGIQPQYGVPYGVTlnPFLSPFGLPCKQPAWGYISALDLKTNEVVWKkrigTPQDSmpfpm 699
Cdd:cd10279 392 ----------EDDPGDFGYNPLGWNTGITPDAT--PPPAAAKRALRKATRGRLVAWDPVTQKAAWR----VEHPG----- 450
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 700 pvpvpfnmgmPMLGGPISTAGNVLFiAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFG 779
Cdd:cd10279 451 ----------PWNGGVLATAGNLVF-QGTADGELAAYDARTGEKLWSFDTGSGIVAAPMTYSVDGEQYVAVLAGWGGAGA 519
|
650
....*....|
gi 16128117 780 TKMGDYIVAY 789
Cdd:cd10279 520 LSGGPPGAAG 529
|
|
| PQQ_MDH |
cd10278 |
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the ... |
168-773 |
2.73e-65 |
|
Large subunit of methanol dehydrogenase (moxF); Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.
Pssm-ID: 199836 [Multi-domain] Cd Length: 553 Bit Score: 227.60 E-value: 2.73e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 168 WPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKqpndpgeiTNEVTPIKVGDTLYLCTAH-QRLFALD-AASGK 245
Cdd:cd10278 1 WVMPGKDYANTRYSPLAQINKDNVKNLKVAWTFSTGVLR--------GHEGAPLVVGDTMYVVTPFpNNVYALDlNDPGK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 246 EKWHYDPelKTNESFQHVTC-----RGVSYHEAKaetaspevmadcprrIILPVNDGRLIAINAENGKlcETFANKgvln 320
Cdd:cd10278 73 ILWKYKP--KQDPSAVAVACcdvvnRGLAYADGK---------------IFFNQLDGHLVALDAKTGK--EVWKVK---- 129
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 321 lqsnMPDTKPGLYEPTSPPIITDKTIVmaGSVTDNFSTRetsGVIRGFDVNTGELLW-AFDPGAK-----DPNAIPSDEH 394
Cdd:cd10278 130 ----NGDPKVGETLTMAPLVVKDKVIV--GISGGEFGVR---GYVTAYDLKTGKLVWrAYSTGPDkdvliGPDFNPFNPH 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 395 TFTFNSP--------------NSWAPAAYDAKLDLVYlpMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTV 460
Cdd:cd10278 201 DGGKDLGlstwpgdawkigggTNWGWYSYDPKLNLVY--YGTGNPGPWNPTQRPGDNKWSMTIFARDPDTGEAKWAYQMT 278
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 461 HHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELVVpaPEKPVPQGAAKGDYVTPTQPFSELSFRPT 540
Cdd:cd10278 279 PHDEWDYDGVNEMILVDQTVDGKKRKLLVHFDRNGFVYTLDRTTGELLS--AEKFDPVNNWKGVDLKTGRPVKDPEKSTH 356
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 541 KDLSGADmwgatmfdqlvcrvmfhqmryegiftppseqgtlVFPGNLGMFEWGGISVDPNRevaianpmALPFVsklipr 620
Cdd:cd10278 357 MDHNVTD----------------------------------ICPSAMGGKDQQPSSYSPKT--------GLFYV------ 388
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 621 gPGNP--ME-QPKDAKGTGtesgiqpqyGVPY-GVTLNPFLSPFGlpckqpAWGYISALDLKTNEVVWKKRigtpqdsmp 696
Cdd:cd10278 389 -PTNHlcMDyEPFEVNYTA---------GQPYvGATLAMYPGPGG------HMGQFKAWDPVTGKTKWEIK--------- 443
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16128117 697 fpmpvpvpfnMGMPMLGGPISTAGNVLFIaATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAG 773
Cdd:cd10278 444 ----------ERFPVWSGTLATAGGLVFY-GTLDGWFKAVDAKTGKLLWKFKLPSGIIGNPITYKHDGKQYVAVLSG 509
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
670-768 |
3.33e-06 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 50.02 E-value: 3.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 670 GYISALDLKTNEVVWKKRIGTPQdsmpfpmpvpvpfnmgmpMLGGPISTAGNVLFIAaTADNYLRAYNMSNGEKLWQGRL 749
Cdd:cd10276 48 GQVSAFNATTGKIIWETSLSGKG------------------FLGGTPAVGNGKIFVG-TESGYLYALDAKDGSELWRTEV 108
|
90
....*....|....*....
gi 16128117 750 PAGGQATPMTYeVNGKQYV 768
Cdd:cd10276 109 SDSQLLSPPTY-ADGKIYV 126
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
181-508 |
7.45e-06 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 49.04 E-value: 7.45e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 181 SPLKQInaDNVHNLKEAWVFRTGDVKqpndpGEITNEVTPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELK----- 255
Cdd:COG1520 21 APLPEF--EPSVKVKQLWSASVGDGV-----GKGYSRLAPAVAGDRVYAADADGRVAALDAATGKELWRVDLGEPlsggv 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 256 -TNESFQHVTCRG---VSYHEAKAE-----TASPEVMADcPR----RIILPVNDGRLIAINAENGKLCETFANKG-VLNL 321
Cdd:COG1520 94 gADGGLVVVGTEDgevIALDADDGEelwraRLSSEVLAA-PAvaggRVVVRTGDGRVYALDAATGERLWSYQRPVpALTL 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 322 QSnmpdtkpglyepTSPPIITDKTIVMAGSvtdnfstretSGVIRGFDVNTGELLWafdpgakdpnaipsdEHTftfnsp 401
Cdd:COG1520 173 RG------------TSSPVIVGGAVLVGFA----------NGKLVALDLANGQPLW---------------EQR------ 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 402 nswapaaydakldlVYLPMGVTtpdiwggnrtpEQER---------------YASS----ILALNATTGKLAWSyqtvhH 462
Cdd:COG1520 210 --------------VAQPRGRT-----------ELERlvdvdgtpvvdggvvYAVAyqgrLAALDLRSGRVLWS-----R 259
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 16128117 463 DLwdmdlpaqPTLADITVNGQKvpvIYAPAKTGNIFVLDRRNGELV 508
Cdd:COG1520 260 DL--------SSYTGLAVDGNN---LYVTDDDGRVWALDRRNGAEL 294
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
225-253 |
1.11e-05 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 42.95 E-value: 1.11e-05
10 20
....*....|....*....|....*....
gi 16128117 225 DTLYLCTAHQRLFALDAASGKEKWHYDPE 253
Cdd:pfam01011 1 GTVYLGSDDGYLYALDAETGKVLWSFKTG 29
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
670-775 |
2.00e-05 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 46.63 E-value: 2.00e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 670 GYISALDLKTNEVVWKKRIGTPqdsmpfpmpvpvpfnmgmpmLGGPISTAGNVLFIaATADNYLRAYNMSNGEKLWQGRL 749
Cdd:pfam13360 3 GVVTALDAATGAELWRVDLETG--------------------LGGGVAVDGGRLFV-ATGGGQLVALDAATGKLLWRQTL 61
|
90 100
....*....|....*....|....*.
gi 16128117 750 PAGGQATPmtyEVNGKQYVVISAGGH 775
Cdd:pfam13360 62 SGEVLGAP---LVAGGRVFVVAGDGS 84
|
|
| BamB_YfgL |
cd10276 |
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is ... |
217-508 |
6.50e-05 |
|
Beta-barrel assembly machinery (Bam) complex component B and related proteins; BamB (YflG) is a non-essential component of the beta-barrel assembly machinery (Bam), a multi-subunit complex that inserts proteins with beta-barrel topology into the outer membrane. BamB has been found to interact with BamA, which in turn binds and stabilizes pre-folded beta-barrel proteins; it has been suggested that BamB participates in the stabilization.
Pssm-ID: 199834 [Multi-domain] Cd Length: 358 Bit Score: 45.79 E-value: 6.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 217 EVTPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESfqhvtcRGVSYHEAK--AETASPEVMA---------- 284
Cdd:cd10276 31 DLTPVVAGDMVYAADANGQVSAFNATTGKIIWETSLSGKGFLG------GTPAVGNGKifVGTESGYLYAldakdgselw 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 285 ---------DCPR-----RIILPVNDGRLIAINAENGKLCETFANkgvlnlqsnmpdTKPGLYEPTSPPIITDKTIVMAG 350
Cdd:cd10276 105 rtevsdsqlLSPPtyadgKIYVGTGDGRLYYCNAETGKVVWNRTS------------TAPELSLRGGAAPVGAYDVVFVG 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 351 svtdnfstrETSGVIRGFDVNTGELLWAF----------DPGAKDPNAIPSDEHTFTFnspnSWAPAAYDAKLDlvyLPM 420
Cdd:cd10276 173 ---------DGNGTVVALNTGTGVDIWEFsvseprgrteLPRMIDSSVTYVVVGGYLY----STSYQGYLVALD---FES 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 421 G--VTTPDIWGGNRT--PEQERY-----ASSILALNATTGKLAWSYqtvhhdlwDMDLPAQPTLADITVNGQkvpVIYAP 491
Cdd:cd10276 237 GqfLWSRKASGGTSTstDANGRVyvgdgEGSLYCLDASTGDELWSQ--------TVLLGRVLSSPAIYVGVY---IYVTD 305
|
330
....*....|....*..
gi 16128117 492 AKTGNIFVLDRRNGELV 508
Cdd:cd10276 306 NAEGYLYCLKDNDGLTV 322
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
224-377 |
2.33e-04 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 44.15 E-value: 2.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 224 GDTLYLCTAHQRLFALDAASGKEKWHydpelktnesfQHVTcrgvsyheakAETASPEVMADcpRRIILPVNDGRLIAIN 303
Cdd:TIGR03300 105 GGLVFVGTEKGEVIALDAEDGKELWR-----------AKLS----------SEVLSPPLVAN--GLVVVRTNDGRLTALD 161
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128117 304 AENGKLCETFANKG-VLNLQSnmpdtkpglyepTSPPIITDKTIVMAGSvtdnfstretSGVIRGFDVNTGELLW 377
Cdd:TIGR03300 162 AATGERLWTYSRVTpPLTLRG------------SASPVIADGGVLVGFA----------GGKLVALDLQTGQPLW 214
|
|
| PQQ |
COG1520 |
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell ... |
670-751 |
2.47e-04 |
|
Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441129 [Multi-domain] Cd Length: 370 Bit Score: 44.03 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 670 GYISALDLKTNEVVWKKRIGTPqdsmpfpmpvpvpfnmgmpmLGGPISTAGNVLFIAaTADNYLRAYNMSNGEKLWQGRL 749
Cdd:COG1520 67 GRVAALDAATGKELWRVDLGEP--------------------LSGGVGADGGLVVVG-TEDGEVIALDADDGEELWRARL 125
|
..
gi 16128117 750 PA 751
Cdd:COG1520 126 SS 127
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
224-457 |
2.86e-04 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 43.16 E-value: 2.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 224 GDTLYLCTAHQRLFALDAASGKEKWHYDPElktnesfqhvtcrgvsyheakAETASPEVMADcpRRIILPVNDGRLIAIN 303
Cdd:pfam13360 33 GGRLFVATGGGQLVALDAATGKLLWRQTLS---------------------GEVLGAPLVAG--GRVFVVAGDGSLIALD 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 304 AENGKLCETF-ANKGVLNLQSNmpdtkpglyeptSPPIITDKTIVMAGSvtdnfstretSGVIRGFDVNTGELLW----A 378
Cdd:pfam13360 90 AADGRRLWSYqRSGEPLALRSS------------GSPAVVGDTVVAGFS----------SGKLVALDPATGKVRWeaplA 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 379 FDPGA------KDPNAIPSDEHTFTFNSPNSWAPAAYDAK------LDLVYLPMGVTTPD--IWGGNRTPEqeryassIL 444
Cdd:pfam13360 148 APRGTnelerlVDITGTPVVAGGRVFASAYQGRLVAFDAAtgrrlwTREISGPNGPILDGdlLYVVSDDGE-------LY 220
|
250
....*....|...
gi 16128117 445 ALNATTGKLAWSY 457
Cdd:pfam13360 221 ALDRATGAVVWKT 233
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
443-467 |
8.35e-04 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 37.56 E-value: 8.35e-04
10 20
....*....|....*....|....*
gi 16128117 443 ILALNATTGKLAWSYQTVHHDLWDM 467
Cdd:pfam01011 12 LYALDAETGKVLWSFKTGGAVLSSP 36
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
667-694 |
9.68e-04 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 37.17 E-value: 9.68e-04
10 20
....*....|....*....|....*...
gi 16128117 667 PAWGYISALDLKTNEVVWKKRIGTPQDS 694
Cdd:pfam01011 7 SDDGYLYALDAETGKVLWSFKTGGAVLS 34
|
|
| assembly_YfgL |
TIGR03300 |
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a ... |
670-751 |
1.17e-03 |
|
outer membrane assembly lipoprotein YfgL; Members of this protein family are YfgL, a lipoprotein component of a complex that acts protein insertion into the bacterial outer membrane. Other members of this complex are NlpB, YfiO, and YaeT. This protein contains multiple copies of a repeat that, in other contexts, are associated with binding of the coenzyme PQQ. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 274511 [Multi-domain] Cd Length: 377 Bit Score: 41.84 E-value: 1.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 670 GYISALDLKTNEVVWKKRIGTPqdsmpfpmpvpvpfnmgmpmLGGPISTAGNVLFIAaTADNYLRAYNMSNGEKLWQGRL 749
Cdd:TIGR03300 75 GTVAALDAETGKRLWRVDLDER--------------------LSGGVGADGGLVFVG-TEKGEVIALDAEDGKELWRAKL 133
|
..
gi 16128117 750 PA 751
Cdd:TIGR03300 134 SS 135
|
|
| PQQ_2 |
pfam13360 |
PQQ-like domain; This domain contains several repeats of the PQQ repeat. |
363-508 |
1.92e-03 |
|
PQQ-like domain; This domain contains several repeats of the PQQ repeat.
Pssm-ID: 433144 [Multi-domain] Cd Length: 233 Bit Score: 40.46 E-value: 1.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 363 GVIRGFDVNTGELLWAFDPGAKDPNAIPSDE-HTF----------------------TFNSPNSWAPAAYDaklDLVYlp 419
Cdd:pfam13360 3 GVVTALDAATGAELWRVDLETGLGGGVAVDGgRLFvatgggqlvaldaatgkllwrqTLSGEVLGAPLVAG---GRVF-- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128117 420 mgVTTPDiwggnrtpeqeryaSSILALNATTGKLAWSYQTVHHDLWdMDLPAQPTLADITVngqkvpviYAPAKTGNIFV 499
Cdd:pfam13360 78 --VVAGD--------------GSLIALDAADGRRLWSYQRSGEPLA-LRSSGSPAVVGDTV--------VAGFSSGKLVA 132
|
....*....
gi 16128117 500 LDRRNGELV 508
Cdd:pfam13360 133 LDPATGKVR 141
|
|
| PQQ |
smart00564 |
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline ... |
220-251 |
2.97e-03 |
|
beta-propeller repeat; Beta-propeller repeat occurring in enzymes with pyrrolo-quinoline quinone (PQQ) as cofactor, in Ire1p-like Ser/Thr kinases, and in prokaryotic dehydrogenases.
Pssm-ID: 128836 [Multi-domain] Cd Length: 33 Bit Score: 35.97 E-value: 2.97e-03
10 20 30
....*....|....*....|....*....|...
gi 16128117 220 PIKVGD-TLYLCTAHQRLFALDAASGKEKWHYD 251
Cdd:smart00564 1 PVVLSDgTVYVGSTDGTLYALDAKTGEILWTYK 33
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
725-757 |
4.03e-03 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 35.63 E-value: 4.03e-03
10 20 30
....*....|....*....|....*....|...
gi 16128117 725 IAATADNYLRAYNMSNGEKLWQGRLPAGGQATP 757
Cdd:pfam01011 4 YLGSDDGYLYALDAETGKVLWSFKTGGAVLSSP 36
|
|
| PQQ |
pfam01011 |
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller ... |
288-323 |
6.67e-03 |
|
PQQ enzyme repeat; The family represent a single repeat of a beta propeller. This propeller has been found in several enzymes which utilize pyrrolo-quinoline quinone as a prosthetic group.
Pssm-ID: 395799 [Multi-domain] Cd Length: 36 Bit Score: 34.86 E-value: 6.67e-03
10 20 30
....*....|....*....|....*....|....*.
gi 16128117 288 RRIILPVNDGRLIAINAENGKLCETFANKGVLNLQS 323
Cdd:pfam01011 1 GTVYLGSDDGYLYALDAETGKVLWSFKTGGAVLSSP 36
|
|
| |
