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Conserved domains on  [gi|16128299|ref|NP_414848|]
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choline:H(+) symporter [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

choline transporter( domain architecture ID 10013377)

choline transporter BetT is a high-affinity, proton-driven, secondary transporter, and is part of the Bet system, which is involved in the synthesis of glycine betaine from externally supplied choline

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-677 0e+00

choline transport protein BetT; Provisional


:

Pssm-ID: 236635  Cd Length: 679  Bit Score: 1407.52  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    1 MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSV 80
Cdd:PRK09928   3 MTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSI 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   81 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA 160
Cdd:PRK09928  83 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  161 LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIAL 240
Cdd:PRK09928 163 LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIAL 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  241 SVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWT 320
Cdd:PRK09928 243 SVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWT 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  321 LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLL 400
Cdd:PRK09928 323 LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEAMAHPERGFYSLL 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  401 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 480
Cdd:PRK09928 403 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 482
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  481 MGLPFSFVIFFVMAGLYKSLKVEDYRRESANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQ 560
Cdd:PRK09928 483 MGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTAPRLVGLQDRLNWKQRLSRVMNYPGTRYTRRMLDTVCRPAMEEVAQ 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  561 ELRLRGAYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMD 640
Cdd:PRK09928 563 ELRLRGAYVELNELPPEEDERLGHLDLLVHLGDEQNFVYQIWPQRYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMD 642
                        650       660       670
                 ....*....|....*....|....*....|....*..
gi 16128299  641 YSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA 677
Cdd:PRK09928 643 YSKEQVINDILDQYERHLNFLHLHREAPGNSVMFPDA 679
 
Name Accession Description Interval E-value
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-677 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 1407.52  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    1 MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSV 80
Cdd:PRK09928   3 MTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSI 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   81 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA 160
Cdd:PRK09928  83 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  161 LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIAL 240
Cdd:PRK09928 163 LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIAL 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  241 SVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWT 320
Cdd:PRK09928 243 SVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWT 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  321 LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLL 400
Cdd:PRK09928 323 LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEAMAHPERGFYSLL 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  401 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 480
Cdd:PRK09928 403 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 482
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  481 MGLPFSFVIFFVMAGLYKSLKVEDYRRESANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQ 560
Cdd:PRK09928 483 MGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTAPRLVGLQDRLNWKQRLSRVMNYPGTRYTRRMLDTVCRPAMEEVAQ 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  561 ELRLRGAYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMD 640
Cdd:PRK09928 563 ELRLRGAYVELNELPPEEDERLGHLDLLVHLGDEQNFVYQIWPQRYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMD 642
                        650       660       670
                 ....*....|....*....|....*....|....*..
gi 16128299  641 YSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA 677
Cdd:PRK09928 643 YSKEQVINDILDQYERHLNFLHLHREAPGNSVMFPDA 679
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-515 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 683.80  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   1 MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSV 80
Cdd:COG1292   1 MSDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  81 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGA-GQTIEAARQAMVWTLFHYGLTGWSMYALMGM 159
Cdd:COG1292  81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGVePGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299 160 ALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIA 239
Cdd:COG1292 161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299 240 LSVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDrPVEWMNNW 319
Cdd:COG1292 241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYG-DTGWLGGW 319
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299 320 TLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSL 399
Cdd:COG1292 320 TVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAAGVEAALFAL 399
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299 400 LAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDinsDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTV 479
Cdd:COG1292 400 LEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDE---EPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASI 476
                       490       500       510
                ....*....|....*....|....*....|....*.
gi 16128299 480 IMGLPFSFVIFFVMAGLYKSLKVEDYRRESANRDTA 515
Cdd:COG1292 477 ITALPFSFVLLLMCVSLVKALREDPRRLRSAEAEAA 512
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
17-503 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 613.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    17 VFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSW 96
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    97 AAMLFAAGIGIDLMFFSVAEPVTQYMQ-PPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIR 175
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   176 SALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDK 255
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   256 GIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFVG 335
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTGGWLGGWTIFYWAWWIAWAPFVG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   336 LFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLLAQYPAFTFSASVATI 415
Cdd:pfam02028 321 MFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLADAVEAGPPAALFALLEQLPLGTILSVLALL 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   416 TGLLFYVTSADSGALVLGNFTSQLKDinsDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAG 495
Cdd:pfam02028 401 LIIIFFVTSADSGTLVIAMLSSGGDL---NPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCIS 477

                  ....*...
gi 16128299   496 LYKSLKVE 503
Cdd:pfam02028 478 LFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
55-503 0e+00

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 612.82  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    55 GWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIE- 133
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTt 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   134 AARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIG 213
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   214 VVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVG 293
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   294 DYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSA 373
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNSA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   374 LYEIIHGGaAFAEEAMVHPE--RGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLR 451
Cdd:TIGR00842 321 LLLQQNGG-FINGPFVVETNgaRALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGGQLGEEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 16128299   452 VFWSVAIGLLTLGMLMTNG-ISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVE 503
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGGsLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
 
Name Accession Description Interval E-value
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-677 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 1407.52  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    1 MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSV 80
Cdd:PRK09928   3 MTDLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSI 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   81 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA 160
Cdd:PRK09928  83 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  161 LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIAL 240
Cdd:PRK09928 163 LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIAL 242
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  241 SVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWT 320
Cdd:PRK09928 243 SVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPTEWMNNWT 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  321 LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLL 400
Cdd:PRK09928 323 LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIHGNAAFAEEAMAHPERGFYSLL 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  401 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 480
Cdd:PRK09928 403 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSKLKDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 482
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  481 MGLPFSFVIFFVMAGLYKSLKVEDYRRESANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQ 560
Cdd:PRK09928 483 MGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTAPRLVGLQDRLNWKQRLSRVMNYPGTRYTRRMLDTVCRPAMEEVAQ 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  561 ELRLRGAYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMD 640
Cdd:PRK09928 563 ELRLRGAYVELNELPPEEDERLGHLDLLVHLGDEQNFVYQIWPQRYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMD 642
                        650       660       670
                 ....*....|....*....|....*....|....*..
gi 16128299  641 YSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA 677
Cdd:PRK09928 643 YSKEQVINDILDQYERHLNFLHLHREAPGNSVMFPDA 679
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-515 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 683.80  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   1 MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSV 80
Cdd:COG1292   1 MSDKNKEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYGKI 80
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  81 KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGA-GQTIEAARQAMVWTLFHYGLTGWSMYALMGM 159
Cdd:COG1292  81 RLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGVePGSPEAARWAMAYTFFHWGLHAWAIYALVGL 160
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299 160 ALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIA 239
Cdd:COG1292 161 ALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIIIIA 240
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299 240 LSVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDrPVEWMNNW 319
Cdd:COG1292 241 VITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYG-DTGWLGGW 319
                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299 320 TLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSL 399
Cdd:COG1292 320 TVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELNGGGDLAEAVAAGVEAALFAL 399
                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299 400 LAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDinsDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTV 479
Cdd:COG1292 400 LEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDE---EPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTASI 476
                       490       500       510
                ....*....|....*....|....*....|....*.
gi 16128299 480 IMGLPFSFVIFFVMAGLYKSLKVEDYRRESANRDTA 515
Cdd:COG1292 477 ITALPFSFVLLLMCVSLVKALREDPRRLRSAEAEAA 512
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
17-503 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 613.39  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    17 VFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSW 96
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    97 AAMLFAAGIGIDLMFFSVAEPVTQYMQ-PPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIR 175
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   176 SALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDK 255
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   256 GIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFVG 335
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGDTGGWLGGWTIFYWAWWIAWAPFVG 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   336 LFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLLAQYPAFTFSASVATI 415
Cdd:pfam02028 321 MFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGDLADAVEAGPPAALFALLEQLPLGTILSVLALL 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   416 TGLLFYVTSADSGALVLGNFTSQLKDinsDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAG 495
Cdd:pfam02028 401 LIIIFFVTSADSGTLVIAMLSSGGDL---NPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCIS 477

                  ....*...
gi 16128299   496 LYKSLKVE 503
Cdd:pfam02028 478 LFKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
55-503 0e+00

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 612.82  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    55 GWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIE- 133
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTt 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   134 AARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIG 213
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   214 VVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVG 293
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   294 DYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSA 373
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDGKGGWPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNSA 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   374 LYEIIHGGaAFAEEAMVHPE--RGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLR 451
Cdd:TIGR00842 321 LLLQQNGG-FINGPFVVETNgaRALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGGQLGEEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 16128299   452 VFWSVAIGLLTLGMLMTNG-ISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVE 503
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSGGsLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
4-502 2.77e-66

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 226.54  E-value: 2.77e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299    4 LSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYY------LLAATLYIVFvvciacSRF 77
Cdd:PRK03356   1 MKNEKKKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFewymvvMLFGWFWLVF------GPY 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   78 GSVKLGPEqsKPEFSLLSWAAMLFAAGIGIDLMFFSVAEpVTQYMQ-PPEGA-GQTIEAARQAMVWTLFHYGLTGWSMYA 155
Cdd:PRK03356  75 AKKRLGDE--KPEFSTASWIFMMFASCTSAAVLFWGSIE-IYYYIStPPFGLePNSTGAKELGLAYSLFHWGPLPWATYS 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  156 LMGMALGYFSYRYNLPLtIR--SALYPIFG-KRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMA 232
Cdd:PRK03356 152 FLSVAFGYFFFVRKMDV-IRpsSTLVPLVGeKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQ 230
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  233 AKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRP 312
Cdd:PRK03356 231 LDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPIGKG 310
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  313 vEWMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALyeiihggaafaeEAMVHP 392
Cdd:PRK03356 311 -GFPQGWTVFYWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTL------------LLMDKN 377
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  393 ERGFYSLLAQYPAF--------TFSASVATITGLLFY-----VTSADSGALVLGNFTSQLKDINSDAPGWLRVFWSVAIG 459
Cdd:PRK03356 378 IINIPNLIEQYGVAraiietwaALPLSTATMWGFFILcfiatVTLINACSYTLAMSTCREVRDGEEPPLLVRIGWSILVG 457
                        490       500       510       520
                 ....*....|....*....|....*....|....*....|...
gi 16128299  460 LLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKV 502
Cdd:PRK03356 458 IIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQ 500
PRK09950 PRK09950
putative transporter; Provisional
20-511 2.48e-65

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 223.90  E-value: 2.48e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299   20 TSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGpeQSKPEFSLLSWAAM 99
Cdd:PRK09950  15 TSLLAVFFIVAALSLFPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLG--EGKPEYSTLSWLFM 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  100 LFAAGIGIDLMFFSVAEPVTQYMQPPEG-AGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGY-FSYRYNLPLTIRSA 177
Cdd:PRK09950  93 FICAGLGSSTLYWGVMEWAYYYQTPGLNiAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYhFHVRKNKGLSLSGI 172
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  178 LYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGI 257
Cdd:PRK09950 173 IAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFCLSSYIGIDNGL 252
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  258 RVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTL-----NSFAFDRpvewmnNWTLFFWAWWVAWSP 332
Cdd:PRK09950 253 QRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQMSLftdpmGDGSFTR------NWTVFYWLWWISYTP 326
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  333 FVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHG--------GAAFAEEAMVHpergfysLLAQYP 404
Cdd:PRK09950 327 GVAMFVTRVSRGRKIKEVIWGLILGSSVGCWFFFGVLESYAIHQFINGvinvpqilNTLGGETAVQQ-------LLSSLP 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128299  405 AFTFSASVATITGLLFYVTSADSGAL-VLGNFTSQLKDINSDAPGwLRVFWSVAIGLLTLGMLMTNG-ISALQNTTVIMG 482
Cdd:PRK09950 400 AGKLFLAAYLGIMIIFLASHMDAVAYtMAATSTRNLREGDDPDRG-LRLFWCVVITLIPLSILFTGAsLDTMKTTVVLTA 478
                        490       500
                 ....*....|....*....|....*....
gi 16128299  483 LPFSFVIFFVMAGLYKSLKvEDYRRESAN 511
Cdd:PRK09950 479 LPFLVILLIKVYGFIRWLK-QDYADVPAH 506
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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