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Conserved domains on  [gi|226524701|ref|NP_414907|]
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IS3 element protein InsE [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

transposase( domain architecture ID 11459289)

transposase binds to the end of a transposon and catalyzes the movement of the transposon to another part of the genome by a cut and paste mechanism or a replicative transposition mechanism; similar to Escherichia coli IS150 protein InsAB

CATH:  1.10.10.10
Gene Ontology:  GO:0006313|GO:0003677|GO:0004803
PubMed:  20885819

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
9-94 7.16e-13

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


:

Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 58.78  E-value: 7.16e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226524701  9 KKPRKQHSPEFRSEALKLAERIGVT--AAARELSLYESQLYNWRSKQQNQQTSS----ERELEMSTEIARLKRQLAERDE 82
Cdd:COG2963   2 SKKRRRYSPEFKAEAVRLVLEGGASvaEVARELGISPSTLYRWVRQYREGGLGGfpgdGRTTPEQAEIRRLRKELRRLEM 81

                        90
                ....*....|..
gi 226524701 83 ELAILQKAATYF 94
Cdd:COG2963  82 ENDILKKAAALL 93
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
9-94 7.16e-13

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 58.78  E-value: 7.16e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226524701  9 KKPRKQHSPEFRSEALKLAERIGVT--AAARELSLYESQLYNWRSKQQNQQTSS----ERELEMSTEIARLKRQLAERDE 82
Cdd:COG2963   2 SKKRRRYSPEFKAEAVRLVLEGGASvaEVARELGISPSTLYRWVRQYREGGLGGfpgdGRTTPEQAEIRRLRKELRRLEM 81

                        90
                ....*....|..
gi 226524701 83 ELAILQKAATYF 94
Cdd:COG2963  82 ENDILKKAAALL 93
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 9-78 5.61e-05

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 38.10  E-value: 5.61e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 226524701   9 KKPRKQHSPEFRSEALKLAERIGVTAA--ARELSLYESQLYNWRSKQQNQQTSSE---RELEMSTEIARLKRQLA 78
Cdd:pfam01527  1 MKKRRRFSEEFKLRAVKEVLEPGRTVKevARRHGVSPNTLYQWRRQYEGGMGASParpRLTALEEENRRLKRELA 75
 
Name Accession Description Interval E-value
InsE COG2963
Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];
9-94 7.16e-13

Transposase InsE and inactivated derivatives [Mobilome: prophages, transposons];


Pssm-ID: 442203 [Multi-domain]  Cd Length: 93  Bit Score: 58.78  E-value: 7.16e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 226524701  9 KKPRKQHSPEFRSEALKLAERIGVT--AAARELSLYESQLYNWRSKQQNQQTSS----ERELEMSTEIARLKRQLAERDE 82
Cdd:COG2963   2 SKKRRRYSPEFKAEAVRLVLEGGASvaEVARELGISPSTLYRWVRQYREGGLGGfpgdGRTTPEQAEIRRLRKELRRLEM 81

                        90
                ....*....|..
gi 226524701 83 ELAILQKAATYF 94
Cdd:COG2963  82 ENDILKKAAALL 93
HTH_Tnp_1 pfam01527
Transposase; Transposase proteins are necessary for efficient DNA transposition. This family ...
 9-78 5.61e-05

Transposase; Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.


Pssm-ID: 426308 [Multi-domain]  Cd Length: 75  Bit Score: 38.10  E-value: 5.61e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 226524701   9 KKPRKQHSPEFRSEALKLAERIGVTAA--ARELSLYESQLYNWRSKQQNQQTSSE---RELEMSTEIARLKRQLA 78
Cdd:pfam01527  1 MKKRRRFSEEFKLRAVKEVLEPGRTVKevARRHGVSPNTLYQWRRQYEGGMGASParpRLTALEEENRRLKRELA 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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