|
Name |
Accession |
Description |
Interval |
E-value |
| PRK15127 |
PRK15127 |
multidrug efflux RND transporter permease subunit AcrB; |
1-1049 |
0e+00 |
|
multidrug efflux RND transporter permease subunit AcrB;
Pssm-ID: 185081 [Multi-domain] Cd Length: 1049 Bit Score: 2173.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:PRK15127 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
Cdd:PRK15127 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK15127 161 NMKDPISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
Cdd:PRK15127 241 TSTEEFGKILLKVNQDGSRVRLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
Cdd:PRK15127 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:PRK15127 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLP 560
Cdd:PRK15127 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGNILRSTGRYLVLYLIIVVGMAYLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 561 SSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
Cdd:PRK15127 561 SSFLPDEDQGVFLTMVQLPAGATQERTQKVLNEVTDYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720
Cdd:PRK15127 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLGEAAKHPDMLVGVRPNG 720
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
Cdd:PRK15127 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAIS 880
Cdd:PRK15127 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEELASKLPTGVGYDWTGMSYQERLSGNQAPALYAIS 880
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960
Cdd:PRK15127 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
Cdd:PRK15127 961 IEATLEAVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
|
....*....
gi 16128446 1041 EHSHTVDHH 1049
Cdd:PRK15127 1041 EHSHTVDHH 1049
|
|
| 2A0602 |
TIGR00915 |
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins ... |
1-1046 |
0e+00 |
|
The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate]
Pssm-ID: 273335 [Multi-domain] Cd Length: 1044 Bit Score: 1919.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:TIGR00915 1 MAKFFIDRPIFAWVIAIIIMLAGTLSILSLPVSQYPSIAPPAITVSASYPGASAQTVQDTVTQVIEQNMNGIDGLRYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
Cdd:TIGR00915 81 SSDSDGSMTITLTFEQGTDPDIAQVQVQNKLQLATPLLPQEVQRQGVRVEKASSNFLMVIGLVSDDGSMTKEDLSDYAAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:TIGR00915 161 NMVDPLSRLEGVGDVQLFGSQYAMRIWLDPAKLNSYQLTPADVISAISAQNAQISAGQLGGLPAVPGQQLNATIIAQTRL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
Cdd:TIGR00915 241 QTPEQFENILLKVNTDGSQVRLKDVARVELGGENYSISARFNGKPASGLAIKLATGANALDTAKAVKAELAVLEPFFPQG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
Cdd:TIGR00915 321 MKYVYPYDTTPFVEASIEEVVHTLIEAIVLVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:TIGR00915 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLP 560
Cdd:TIGR00915 481 SVLVALILTPALCATMLKPIEKGEHHEKKGGFFGWFNRMFDSSTHGYENGVGKILRRRGRYLLVYVLLVGGMVFLFVRLP 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 561 SSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
Cdd:TIGR00915 561 TSFLPDEDQGVFMTIVQLPAGATAERTQAVLAQVTKYLLAKEKANVESVFTVNGFSFAGRGQNMGMAFIRLKDWEERTGK 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDmLTSVRPNG 720
Cdd:TIGR00915 641 ENSVFAIAGRATGHFMQIKDAMVIAFVPPAILELGNATGFDFFLQDRAGLGHEALLQARNQLLGLAAQNPA-LTRVRPNG 719
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
Cdd:TIGR00915 720 LEDEPQLKIDIDREKAQALGVSIADINTTLSTAWGSSYVNDFIDRGRVKRVYVQAEEDARMSPEDINKWYVRNASGEMVP 799
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAIS 880
Cdd:TIGR00915 800 FSAFATVRWEYGSPQLERYNGLPSMEILGSAAPGVSTGQAMAAMEAIAQKLPPGFGFSWTGMSYEERLSGSQAPALYALS 879
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKeGKGL 960
Cdd:TIGR00915 880 LLVVFLCLAALYESWSIPVSVMLVVPLGIIGALLATTLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAKELMAQ-GKSI 958
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI 1040
Cdd:TIGR00915 959 VEAALEAARLRLRPILMTSLAFILGVVPLAISTGAGSGSQHAIGTGVFGGMVTATVLAIFFVPLFYVVVRRLFKRKAHEK 1038
|
....*.
gi 16128446 1041 EHSHTV 1046
Cdd:TIGR00915 1039 EMSVEH 1044
|
|
| PRK10555 |
PRK10555 |
multidrug efflux RND transporter permease AcrD; |
1-1019 |
0e+00 |
|
multidrug efflux RND transporter permease AcrD;
Pssm-ID: 182544 [Multi-domain] Cd Length: 1037 Bit Score: 1639.16 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:PRK10555 1 MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRITANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 81 NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
Cdd:PRK10555 81 QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK10555 161 NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTTKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
Cdd:PRK10555 241 QTPEQFRDITLRVNQDGSEVTLGDVATVELGAEKYDYLSRFNGKPASGLGVKLASGANEMATAKLVLNRLDELAQYFPHG 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
Cdd:PRK10555 321 LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSINTLTMFAMVL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:PRK10555 401 AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVSAMVL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 481 SVLVALILTPALCATMLKPIAKGDHgEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLP 560
Cdd:PRK10555 481 SVLVAMILTPALCATLLKPLKKGEH-HGQKGFFGWFNRMFNRNAERYEKGVAKILHRSLRWILIYVLLLGGMVFLFLRLP 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 561 SSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
Cdd:PRK10555 560 TSFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEKVEKYYFTHEKDNVMSVFATVGSGPGGNGQNVARMFIRLKDWDERDSK 639
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDmLTSVRPNG 720
Cdd:PRK10555 640 TGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAKNPE-LTRVRHNG 718
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
Cdd:PRK10555 719 LDDSPQLQIDIDQRKAQALGVSIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP 798
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAIS 880
Cdd:PRK10555 799 FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAIS 878
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDlMDKEGKGL 960
Cdd:PRK10555 879 LLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANE-MNQKGHDL 957
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 16128446 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:PRK10555 958 FEATLHASRQRLRPILMTSLAFIFGVLPMATSTGAGSGSQHAVGTGVMGGMISATILAI 1016
|
|
| ACR_tran |
pfam00873 |
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are ... |
1-1019 |
0e+00 |
|
AcrB/AcrD/AcrF family; Members of this family are integral membrane proteins. Some are involved in drug resistance. AcrB cooperates with a membrane fusion protein, AcrA, and an outer membrane channel TolC. The structure shows the AcrB forms a homotrimer.
Pssm-ID: 395701 [Multi-domain] Cd Length: 1021 Bit Score: 1491.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:pfam00873 1 MSKFFIRRPIFTLVLAIAILLAGILSFFSLPVDAFPEIAPPTVQVSTSYPGASPEEVEDTVTQPIEQAMNGLDGLKYMSS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 81 NSdSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
Cdd:pfam00873 81 QS-SYGLSSITLTFELGTDIDIARQDVQNRLQLATPLLPEGVQRPGISVIKTSLGPIMVLAVTSPDGSYTQTDLRDYADT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 161 NMKDAISRTSGVGDVQLFG-SQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLggtppvKGQQLNASIIAQTR 239
Cdd:pfam00873 160 NIKPQLSRVPGVGDVQLFGgSEYAMRIWLDPQKLARYGLTLTDVVSALKEQNVNIGAGQL------EGQGLQALIRAQGQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 240 LTSTEEFGKILLKvNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPS 319
Cdd:pfam00873 234 LQSAEDFEKIIVK-NQDGSPVRLRDVATVELGSELYRGFATFNGKPAVGLGVQKLPGANAIETADAVRAKLAELKPTFPQ 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399
Cdd:pfam00873 313 GVEIVVVYDTTPFIRASIEEVVKTLLEAIVLVILVMFLFLQNWRATLIPAIAIPLSLLGTFAVMKAFGFSINTLTLGGLV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 400 LAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
Cdd:pfam00873 393 LAIGLVVDDAIVVVENIERVLEENGLKPLEAAYKSMGEIGGALVAIALVLSAVFLPILFLGGLTGRIFRQFAITIVLAIL 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 480 LSVLVALILTPALCATMLKPIAKGDHGegkkGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRL 559
Cdd:pfam00873 473 LSVLVALTLTPALCATLLKPRREPKHG----GFFRWFNRMFDRLTRGYAKLLAKVLRHTAVVLLVALLLVVGSVWLFVRI 548
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 560 PSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYltKEKNNVESVFAVNGFGFAG--RGQNTGIAFVSLKDWADR 637
Cdd:pfam00873 549 PTEFLPEEDEGVFVTSAQLPPGVSLDQTQRVMKQVEKIL--KEKPEVESVFAVTGFAFSGdnNGPNSGDAFISLKPWKER 626
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 638 PGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELID-QAGLGHEKLTQARNQLLAEAAKHPDmLTSV 716
Cdd:pfam00873 627 PGPEKSVQALIERLRKALKQIPGANVFLFQPIQLRGLGTISGFRSDLQVkIFGDDLDALDEARNQILAALAQLPG-LSDV 705
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 717 RPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADG 796
Cdd:pfam00873 706 RSDGQEDQPQLQVNIDREKAARLGVSIQDINDTLSTALGGSYVNDFPEGGRVYDVVVQLPEDFRSSPEDIGQLYVRNPYG 785
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 797 QMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASK--LPTGVGYDWTGMSYQERLSGNQAP 874
Cdd:pfam00873 786 KMIPLSAFAKIEWGYGPPSINRYNGFRSIVISGNVAAGDSLGDAMEAMAQIAKQvkLPPGYGYTWTGQFEQEQLAGNSLP 865
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 875 SLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMD 954
Cdd:pfam00873 866 ILIALALLVVFLVLAALYESWSDPLSIMLTVPLALVGALLALWLRGLPNSVYAQVGLILLIGLAVKNAILMVEFANELRE 945
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16128446 955 KEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:pfam00873 946 QEGKSLEEAILEACRLRLRPILMTALAAILGVLPLALSTGAGSELQQPLGIVVFGGLVTSTVLTL 1010
|
|
| PRK09577 |
PRK09577 |
multidrug efflux RND transporter permease subunit; |
1-1019 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169981 [Multi-domain] Cd Length: 1032 Bit Score: 1244.74 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:PRK09577 1 MARFFIDRPVFAWVISLFIMLGGIFAIRALPVAQYPDIAPPVVSIYATYPGASAQVVEESVTALIEREMNGAPGLLYTSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 81 NSdSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA 160
Cdd:PRK09577 81 TS-SAGQASLSLTFKQGVNADLAAVEVQNRLKTVEARLPEPVRRDGIQVEKAADNIQLIVSLTSDDGRLTGVELGEYASA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 161 NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240
Cdd:PRK09577 160 NVLQALRRVEGVGKVQFWGAEYAMRIWPDPVKLAALGLTASDIASAVRAHNARVTIGDIGRSAVPDSAPIAATVFADAPL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG 320
Cdd:PRK09577 240 KTPEDFGAIALRARADGSALYLRDVARIEFGGNDYNYPSYVNGKTATGMGIKLAPGSNAVATEKRVRATMDELSRYFPPG 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 321 LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL 400
Cdd:PRK09577 320 VKYQIPYETSSFVRVSMNKVVTTLIEAGVLVFLVMFLFMQNFRATLIPTLVVPVALLGTFGVMLAAGFSINVLTMFGMVL 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 401 AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480
Cdd:PRK09577 400 AIGILVDDAIVVVENVERLMVEEGLSPYDATVKAMKQISGAIVGITVVLTSVFVPMAFFGGAVGNIYRQFALSLAVSIGF 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 481 SVLVALILTPALCATMLKPIAKGDHgeGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLP 560
Cdd:PRK09577 480 SAFLALSLTPALCATLLKPVDGDHH--EKRGFFGWFNRFVARSTQRYATRVGAILKRPLRWLVVYGALTAAAALLFTRLP 557
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 561 SSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKnnVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE 640
Cdd:PRK09577 558 TAFLPDEDQGNFMVMVIRPQGTPLAETMQSVREVESYLRRHEP--VAYTFALGGFNLYGEGPNGGMIFVTLKDWKERKAA 635
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 641 ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPdMLTSVRPNG 720
Cdd:PRK09577 636 RDHVQAIVARINERFAGTPNTTVFAMNSPALPDLGSTSGFDFRLQDRGGLGYAAFVAAREQLLAEGAKDP-ALTDLMFAG 714
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP 800
Cdd:PRK09577 715 TQDAPQLKLDIDRAKASALGVSMDEINTTLAVMFGSDYIGDFMHGSQVRRVIVQADGRHRLDPDDVKKLRVRNAQGEMVP 794
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 801 FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAIS 880
Cdd:PRK09577 795 LAAFATLHWTLGPPQLTRYNGYPSFTINGSAAPGHSSGEAMAAIERIAATLPAGIGYAWSGQSFEERLSGAQAPMLFALS 874
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDkEGKGL 960
Cdd:PRK09577 875 VLVVFLALAALYESWSIPFAVMLVVPLGVIGAVLGVTLRGMPNDIYFKVGLIATIGLSAKNAILIVEVAKDLVA-QRMSL 953
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*....
gi 16128446 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:PRK09577 954 ADAALEAARLRLRPIVMTSLAFGVGVLPLAFASGAASGAQIAIGTGVLGGVITATVLAV 1012
|
|
| AcrB |
COG0841 |
Multidrug efflux pump subunit AcrB [Defense mechanisms]; |
1-1019 |
0e+00 |
|
Multidrug efflux pump subunit AcrB [Defense mechanisms];
Pssm-ID: 440603 [Multi-domain] Cd Length: 1015 Bit Score: 1239.21 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS 80
Cdd:COG0841 3 LSRFFIRRPVAAIVLSLLILLAGLLAYLRLPVEQFPDIDPPTVTVSTTYPGASPEEVESTVTTPIEEALNGVEGIKYITS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 81 NSdSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDgtMTQEDISDYVAA 160
Cdd:COG0841 83 TS-SEGSSSITVEFELGTDIDEALVDVQNAVDRARSDLPEDVEPPGVTKVNPSDFPVMVLALSSDD--LDELELSDYAER 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 161 NMKDAISRTSGVGDVQLFGS-QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGtppvkgQQLNASIIAQTR 239
Cdd:COG0841 160 NIKDRLERVPGVGQVQIFGGrEREIRIWLDPDKLAAYGLTLADVANAIRAQNVDVPAGRIGG------GDREYTVRTNGR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 240 LTSTEEFGKILLKVNqDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPS 319
Cdd:COG0841 234 LKTPEEFENIVIRTN-DGSVVRLGDVARVEDGAEDYRSIARLNGKPAVGLAIQKQPGANALEVADAVRAKLEELQASLPE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 320 GLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMV 399
Cdd:COG0841 313 GVELTIVYDQSEFIRASIEEVVKTLLEAILLVVLVVFLFLRSWRATLIPAVAIPVSLIGTFAVMYLLGFSLNILTLFALV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 400 LAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMA 479
Cdd:COG0841 393 LAIGIVVDDAIVVVENIERHM-EEGLSPLEAAIKGAREVAGAVIASTLTLVAVFLPLAFMGGITGQLFRQFALTVAIALL 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 480 LSVLVALILTPALCATMLKPiakgDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRL 559
Cdd:COG0841 472 ISLFVALTLTPALCARLLKP----HPKGKKGRFFRAFNRGFDRLTRGYGRLLRWALRHRKLTLLVALALLALSVLLFGRL 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 560 PSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEknNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPg 639
Cdd:COG0841 548 PTEFFPEEDQGQIIVSVQLPPGTSLERTEAVVRQVEEILLEVP--EVESVFSVVGFSGGGSGSNSGTIFVTLKPWDERD- 624
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 640 eeNKVEAITMRATRAFSQIKDAMVFAFNLPAIvELGTATGFDFELidqAGLGHEKLTQARNQLLAEAAKHPdMLTSVRPN 719
Cdd:COG0841 625 --RSADEIIARLREKLAKIPGARVFVFQPPAG-GLGSGAPIEVQL---QGDDLEELAAAAEKLLAALRQIP-GLVDVRSD 697
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 720 GLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMV 799
Cdd:COG0841 698 LQLGKPELQLDIDREKAAALGVTVADVASTLRAALGGRYVNDFNRGGREYDVRVQAPEEDRNSPEDLENLYVRTPDGEMV 777
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 800 PFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASK--LPTGVGYDWTGMSYQERLSGNQAPSLY 877
Cdd:COG0841 778 PLSSVATIEEGTGPSSINRYNGQRSVTVSANLAPGVSLGEALAAIEELAAElkLPPGVSIEFTGQAEEEQESFSSLGLAF 857
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 878 AISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMdKEG 957
Cdd:COG0841 858 LLALLLVYLVLAAQFESFIQPLIILLTVPLALIGALLGLLLTGTPLNIYSQIGLIMLIGIVVKNAILLVDFANQLR-EEG 936
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128446 958 KGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:COG0841 937 MSLREAILEAARLRLRPILMTSLATILGLLPLALGTGAGAEFRQPLGIAVIGGLLFSTLLTL 998
|
|
| RND_permease_2 |
NF033617 |
multidrug efflux RND transporter permease subunit; |
5-1017 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 411236 [Multi-domain] Cd Length: 1009 Bit Score: 759.94 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
Cdd:NF033617 4 FIKRPVATLLLSLLILLLGLLAFRKLPVREYPEVDFPTITVSTSYPGASPELMQSSITQPLEQQLAQIEGIDEMTSQS-S 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 85 TGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVE-KSSSSFLMVVGVinTDGTMTQEDISDYVAANMK 163
Cdd:NF033617 83 LGYSTITLQFRLGTDLDVALSEVQAAINAAQSLLPSEAPDPPVYRKaNSADTPIMYIGL--TSEEMPRGQLTDYAERVLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 164 DAISRTSGVGDVQLFGSQY-AMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTS 242
Cdd:NF033617 161 PKLSQINGVGSVDVSGGQRpAMRVWLDPEKMAARGLTADDVRSALNSNNVNSPKGA------VRGDSVVSTVRANDQLKT 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 243 TEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLK 322
Cdd:NF033617 235 AEDYEDLVIKYADNGAPVRLGDVATVELGAENVRNRAWANGVPAVVLGINRQPGANPIEVADEIRALLPELQETLPKNIK 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 323 IVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAI 402
Cdd:NF033617 315 VNVLYDRTRFIRASIDEVESTLLEAVALVILVVFLFLRNLRATLIPAVTVPLSLIGTFAVMYLFGFSINLLTLMALVLAI 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
Cdd:NF033617 395 GLVVDDAIVVVENIHRHI-EEGESPLEAALKGAREIGFTVIAMTLTLVAVYLPILFMGGLTGRLFREFAVTLAGAVIISG 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 483 LVALILTPALCATMLKPIAKGDhgegkkGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSS 562
Cdd:NF033617 474 IVALTLTPMMCSRLLKANEKPG------RFARAVDRFFDGLTARYGRGLKWVLKHRPLTLVVALATLALLPLLYVFIPKE 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 563 FLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKnnVESVFAVNGFGfAGRGQNTGIAFVSLKDWADRpgeEN 642
Cdd:NF033617 548 LAPSEDRGVIFGMIQAPQSISLDYMSAKMRDVEKILSSDPE--VQSLTSFNGVG-GNPGDNTGFGIINLKPWDER---DV 621
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 643 KVEAITMRATRAFSQIKDAMVFAFNLPAIvELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPdMLTSVRPNGLE 722
Cdd:NF033617 622 SAQEIIDRLRPKLAKVPGMDLFLFPLQDL-PGGAGSSLPQYQVTLTPSDYDSLFTWAEKLKEKLRKSP-QFADVDSDLQD 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 723 DTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFS 802
Cdd:NF033617 700 KGPELNVDIDRDKAARLGISMQDIGSTLEVAFGQRQVNTIYTDGNQYKVVLEVDRRYRLNPEALNQIYVRSNDGKLVPLS 779
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 803 AFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLA-SKLPTGVGYDWTGMSYQERLSGNQAPSLYAISL 881
Cdd:NF033617 780 TLAKIEERAAPLSLNHFNQFNSATLSFNLAPGVSLGEAIEALDQAAkELLPSGISGSFQGAARAFQEEGSSLLFLFLLAL 859
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 882 IVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLI 961
Cdd:NF033617 860 AAIYLVLAIQYESFVDPLTILSTVPLAGCGALLALALGGQSMNIYAQIGLITLIGLVKKNGILMVEFANELQRHQGLSRR 939
|
970 980 990 1000 1010
....*....|....*....|....*....|....*....|....*....|....*.
gi 16128446 962 EATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVL 1017
Cdd:NF033617 940 EAIYQAAALRLRPILMTTLAMLLGAIPLMLSTGAGAESRFPLGIVIVGGLGVGTLF 995
|
|
| PRK09579 |
PRK09579 |
multidrug efflux RND transporter permease subunit; |
5-1019 |
0e+00 |
|
multidrug efflux RND transporter permease subunit;
Pssm-ID: 169983 [Multi-domain] Cd Length: 1017 Bit Score: 580.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDS 84
Cdd:PRK09579 7 FIRRPVLASVVSLLIVLLGFQAWSKLQIRQYPQMENALITVTTAYPGANAETIQGYITQPLQQSLASAEGIDYMTSVSRQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 85 TGTVqITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVinTDGTMTQEDISDYVAANMKD 164
Cdd:PRK09579 87 NFSI-ISIYARIGADSDRLFTELLAKANEVKNQLPQDAEDPVLSKEAADASALMYISF--YSEEMSNPQITDYLSRVIQP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 165 AISRTSGVGDVQLFGSQ-YAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTST 243
Cdd:PRK09579 164 KLATLPGMAEAEILGNQvFAMRLWLDPVKLAGFGLSAGDVTQAVRRYNFLSAAGE------VKGEYVVTSINASTELKSA 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 244 EEFGKILLKVNQDgSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKI 323
Cdd:PRK09579 238 EAFAAIPVKTSGD-SRVLLGDVARVEMGAENYDSISSFDGIPSVYIGIKATPSANPLDVIKEVRAIMPELESQLPPNLKV 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 324 VYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIG 403
Cdd:PRK09579 317 SIAYDATLFIQASIDEVVKTLGEAVLIVIVVVFLFLGALRSVLIPVVTIPLSMIGVLFFMQMMGYSINLLTLLAMVLAIG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 404 LLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVL 483
Cdd:PRK09579 397 LVVDDAIVVVENIHRHI-EEGKSPFDAALEGAREIAMPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVIISGI 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 484 VALILTPALCATMLKpiakgdHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSF 563
Cdd:PRK09579 476 VALTLSPMMCALLLR------HEENPSGLAHRLDRLFERLKQRYQRALHGTLNTRPVVLVFAVIVLALIPVLLKFTQSEL 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 564 LPDEDQGVFMTMvqlpAGATQERTQKVLNEVTHYY--LTKEKNNVESVFAVNGFGfagrGQNTGIAFVSLKDWADRpgEE 641
Cdd:PRK09579 550 APEEDQGIIFMM----SSSPQPANLDYLNAYTDEFtpIFKSFPEYYSSFQINGFN----GVQSGIGGFLLKPWNER--ER 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 642 NKVEAITMRATRaFSQIKDAMVFAFNLPAIVelGTATGFDFELIDQAGLGHEKLTQARNQlLAEAAKHPDMLTSVRPNGL 721
Cdd:PRK09579 620 TQMELLPLVQAK-LEEIPGLQIFGFNLPSLP--GTGEGLPFQFVINTANDYESLLQVAQR-VKQRAQESGKFAFLDIDLA 695
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 722 EDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPF 801
Cdd:PRK09579 696 FDKPEVVVDIDRAKAAQMGVSMQDLGGTLATLLGEGEINRFTIDGRSYKVIAQVERPYRDNPGWLNNYYVKNEQGQLLPL 775
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 802 SAFSSSRWEYGSPRLERYNGLPSMEIlgQAAPGKSTGEAMELMEQLA-SKLPTGVGYDWTGMSYQERLSGNQAPSLYAIS 880
Cdd:PRK09579 776 STLITLSDRARPRQLNQFQQLNSAII--SGFPIVSMGEAIETVQQIArEEAPEGFAFDYAGASRQYVQEGSALWVTFGLA 853
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 881 LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLaATFRGLTN-DVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKG 959
Cdd:PRK09579 854 LAIIFLVLAAQFESFRDPLVILVTVPLSICGALI-PLFLGVSSmNIYTQVGLVTLIGLISKHGILIVEFANQLRHEQGLS 932
|
970 980 990 1000 1010 1020
....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 960 LIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:PRK09579 933 RREAIEEAAAIRLRPVLMTTAAMVFGMVPLILATGAGAVSRFDIGLVIATGMSIGTLFTL 992
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
4-1017 |
1.25e-137 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 440.62 E-value: 1.25e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 4 FFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSd 83
Cdd:COG3696 8 FSLRNRLLVLLLTLLLAAAGIYSLRRLPIDAFPDITNVQVQVITEAPGLSPEEVEQQVTYPIETALNGLPGVKEVRSIS- 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 84 STGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQ-G-VSvekSSSSFLMVVGVINTDGTMTQED---ISDYV 158
Cdd:COG3696 87 RFGLSVVTVIFEDGTDIYWARQLVLERLQQVREQLPAGVTPElGpIS---TGLGEIYQYTLESDPGKYSLMElrtLQDWV 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 159 aanMKDAISRTSGVGDVQLFG---SQYAMRIwmNPNELNKFQLTPVDVITAIKAQNAQVAAGQLggtpPVKGQQLNasII 235
Cdd:COG3696 164 ---IRPQLRSVPGVAEVNSFGgfvKQYQVLV--DPAKLRAYGLTLDDVIEALERNNANVGGGYI----ERGGQEYL--VR 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 236 AQTRLTSTEEFGKILLKvNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLA-TGANALDTAAAIRAELAKME 314
Cdd:COG3696 233 GIGLIRSLEDIENIVVK-TRNGTPVLLRDVAEVRIGPAPRRGAATLNGEGEVVGGIVLMlKGENALEVIEAVKAKLAELK 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 315 PFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLT 394
Cdd:COG3696 312 PSLPEGVKIVPFYDRSDLIDRAIHTVTKNLLEGALLVILVLFLFLGNLRAALIVALAIPLSLLFAFIVMRLFGISANLMS 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 395 MFGMVLAIGLLVDDAIVVVENVERVMAE-----EGLPPKEATRKSMGQIQGALV-GIAMVLsAVFVPMAFFGGSTGAIYR 468
Cdd:COG3696 392 LGGLAIDFGIIVDGAVVMVENILRRLEEnraagTPRERLEVVLEAAREVRRPIFfATLIII-LVFLPIFTLEGVEGKLFR 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 469 QFSITIVSAMALSVLVALILTPALCATMLKPiaKGDHGEGkkgffgWFNRMFEKsthHYTDSVGGILRSTGRYLVLYLII 548
Cdd:COG3696 471 PMALTVIFALLGALLLSLTLVPVLASLLLRG--KVPEKEN------PLVRWLKR---LYRPLLRWALRHPKLVLAVALVL 539
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 549 VVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHyyLTKEKNNVESVFavngfGFAGR-------- 620
Cdd:COG3696 540 LVLALALFPRLGSEFLPELDEGDLLVMATLPPGISLEESVELGQQVER--ILKSFPEVESVV-----SRTGRaedatdpm 612
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 621 GQNTGIAFVSLKDWADRPGEENKVEAIT-MRAtrAFSQIKDaMVFAFNLP---AIVEL--GTAT-------GFDFELIDQ 687
Cdd:COG3696 613 GVNMSETFVILKPRSEWRSGRTKEELIAeMRE--ALEQIPG-VNFNFSQPiqmRVDELlsGVRAdvavkifGDDLDVLRR 689
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 688 AGlghekltqarnQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGR 767
Cdd:COG3696 690 LA-----------EQIEAVLKTVPGAADVQVERVTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQVYEGER 758
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 768 VKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEI--------LGQAApgkstGE 839
Cdd:COG3696 759 RFDIVVRLPEELRDDPEAIRNLPIPTPSGAQVPLSQVADIEVVEGPNQISRENGRRRIVVqanvrgrdLGSFV-----AE 833
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 840 AMELMEQlASKLPTGVGYDWTGM-----SYQERLSGnqapsLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL 914
Cdd:COG3696 834 AQAKVAE-QVKLPPGYYIEWGGQfenlqRATARLAI-----VVPLALLLIFLLLYLAFGSVRDALLILLNVPFALIGGVL 907
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 915 AATFRGLtndvYFQ----VGLLTTIGLSAKNAILIVEFAKDLMdKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLV 990
Cdd:COG3696 908 ALWLRGM----PLSvsagVGFIALFGVAVLNGVVLVSYINQLR-AEGLDLREAIIEGALERLRPVLMTALVAALGLLPMA 982
|
1050 1060
....*....|....*....|....*..
gi 16128446 991 ISTGAGSGAQNAVGTGVMGGMVTATVL 1017
Cdd:COG3696 983 LSTGPGSEVQRPLATVVIGGLITSTLL 1009
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
5-1017 |
6.20e-118 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 387.93 E-value: 6.20e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
Cdd:PRK10614 7 FIYRPVATILLSLAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVNEMTSSS-S 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 85 TGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGvSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKD 164
Cdd:PRK10614 86 LGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRP-TYRKANPSDAPIMILTLTSDTYSQGQLYDFASTQLAQ 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 165 AISRTSGVGDVQLFGSQY-AMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQlggtppVKGQQLNASIIAQTRLTST 243
Cdd:PRK10614 165 TISQIDGVGDVDVGGSSLpAVRVGLNPQALFNQGVSLDDVRQAISNANVRRPQGA------VEDGTHRWQIQTNDELKTA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 244 EEFGKILLKVNQdGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKI 323
Cdd:PRK10614 239 AEYQPLIIHYNN-GAAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDRIRAKLPELRETIPAAIDL 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 324 VYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIG 403
Cdd:PRK10614 318 QIAQDRSPTIRASLEEVEQTLAISVALVILVVFLFLRSGRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATG 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 404 LLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVL 483
Cdd:PRK10614 398 FVVDDAIVVLENISRHL-EAGMKPLQAALQGVREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLFREFAVTLSVAIGISLL 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 484 VALILTPALCATMLKPIAKGDHGEgKKGffgwFNRMFEKSTHHYTDSVGGILRSTgRYLVLYLIIVVGM-AYLFVRLPSS 562
Cdd:PRK10614 477 VSLTLTPMMCAWLLKSSKPREQKR-LRG----FGRMLVALQQGYGRSLKWVLNHT-RWVGVVLLGTIALnVWLYISIPKT 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 563 FLPDEDQGVFMTMVQlpagATQERT-QKVLNEVTHYY-LTKEKNNVESVfavngFGFAGRGQ-NTGIAFVSLKDWADRpg 639
Cdd:PRK10614 551 FFPEQDTGRLMGFIQ----ADQSISfQAMRGKLQDFMkIIRDDPAVDNV-----TGFTGGSRvNSGMMFITLKPLSER-- 619
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 640 EENKVEAITmRATRAFSQIKDAMVFafnLPAIVEL-----GTATGFDFELI--DQAGLGH--EKLTQARNQLlaeaakhP 710
Cdd:PRK10614 620 SETAQQVID-RLRVKLAKEPGANLF---LMAVQDIrvggrQSNASYQYTLLsdDLAALREwePKIRKALAAL-------P 688
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 711 DmLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWY 790
Cdd:PRK10614 689 E-LADVNSDQQDKGAEMALTYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPLNQYKVVMEVDPRYTQDISALEKMF 767
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 791 VRAADGQMVPFSAFSSsrWE-YGSPRLERYNGLPSMEILG-QAAPGKSTGEAMELMEQLASKL--PTGV--GYDWTGMSY 864
Cdd:PRK10614 768 VINNEGKAIPLSYFAK--WQpANAPLSVNHQGLSAASTISfNLPTGKSLSDASAAIERAMTQLgvPSTVrgSFAGTAQVF 845
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 865 QERLSGNQAPSLYAIslIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAIL 944
Cdd:PRK10614 846 QETMNSQLILILAAI--ATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIM 923
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16128446 945 IVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVL 1017
Cdd:PRK10614 924 MVDFALEAQRNGNLTAQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGAELRQPLGITIVGGLVMSQLL 996
|
|
| PRK10503 |
PRK10503 |
MdtB/MuxB family multidrug efflux RND transporter permease subunit; |
5-1019 |
1.64e-114 |
|
MdtB/MuxB family multidrug efflux RND transporter permease subunit;
Pssm-ID: 182501 [Multi-domain] Cd Length: 1040 Bit Score: 378.69 E-value: 1.64e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 5 FIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdS 84
Cdd:PRK10503 16 FILRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQS-S 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 85 TGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGV-SVEKSSSSFLMVVGVINTDGTMTQedISDYVAANMK 163
Cdd:PRK10503 95 GGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVySKVNPADPPIMTLAVTSTAMPMTQ--VEDMVETRVA 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 164 DAISRTSGVGDVQLFGSQY-AMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGtpPVKGQQLNASiiaqTRLTS 242
Cdd:PRK10503 173 QKISQVSGVGLVTLSGGQRpAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDG--PTRAVTLSAN----DQMQS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 243 TEEFGKILLKVnQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLK 322
Cdd:PRK10503 247 AEEYRQLIIAY-QNGAPIRLGDVATVEQGAENSWLGAWANKQQAIVMNVQRQPGANIIATADSIRQMLPQLTESLPKSVK 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 323 IVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAI 402
Cdd:PRK10503 326 VTVLSDRTTNIRASVDDTQFELMLAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIAT 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 403 GLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSV 482
Cdd:PRK10503 406 GFVVDDAIVVIENISRYI-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAILISA 484
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 483 LVALILTPALCATMLKPIAKGDHGEgkkgFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSS 562
Cdd:PRK10503 485 VVSLTLTPMMCARMLSQESLRKQNR----FSRASERMFDRVIAAYGRGLAKVLNHPWLTLSVALSTLLLTVLLWIFIPKG 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 563 FLPDEDQGVFMTMVQLPA----GATQERTQKVLNEVThyyltkEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRp 638
Cdd:PRK10503 561 FFPVQDNGIIQGTLQAPQsssfANMAQRQRQVADVIL------QDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDER- 633
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 639 geENKVEAITMRATRAFSQIKDAMVFafnLPAIVELG-----TATGFDFELidQAGlGHEKLTQARNQLLAEAAKHPdML 713
Cdd:PRK10503 634 --DDRVQKVIARLQTAVAKVPGVDLY---LQPTQDLTidtqvSRTQYQFTL--QAT-SLDALSTWVPKLMEKLQQLP-QL 704
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 714 TSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRA 793
Cdd:PRK10503 705 SDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTS 784
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 794 ADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKL--PTGVGYDWTG--MSYQERLS 869
Cdd:PRK10503 785 SDGGVVPLSSIATIEQRFGPLSINHLDQFPSTTISFNVPDGYSLGDAVQAIMDTEKTLnlPADITTQFQGstLAFQSALG 864
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 870 GNQAPSLYAIslIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFA 949
Cdd:PRK10503 865 STVWLIVAAV--VAMYIVLGVLYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFA 942
|
970 980 990 1000 1010 1020 1030
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 950 KDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:PRK10503 943 LAAEREQGMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGICMVGGLIVSQVLTL 1012
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
17-1019 |
1.09e-74 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 267.78 E-value: 1.09e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 17 IIIMLAGGLAIL------KLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSdSTGTVQI 90
Cdd:TIGR00914 15 LVLLATLVMAILgiwsynRLPIDAVPDITNVQVQINTSAPGYSPLEVEQRVTYPIETAMAGLPGLETTRSLS-RYGLSQV 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 91 TLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQ------GV------SVEKSSSSFLMVVGVINTDGTMTqedISDYV 158
Cdd:TIGR00914 94 TVIFKDGTDLYFARQLVNERLQQARDNLPEGVSPEmgpistGLgeiflyTVEAEEGARKKDGGAYTLTDLRT---IQDWI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 159 aanMKDAISRTSGVGDVQLFG---SQYAMRIwmNPNELNKFQLTPVDVITAIKAQNAQVAAGQLggtpPVKGQQLnaSII 235
Cdd:TIGR00914 171 ---IRPQLRTVPGVAEVNSIGgyvKQFLVAP--DPEKLAAYGLSLADVVNALERNNQNVGAGYI----ERRGEQY--LVR 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 236 AQTRLTSTEEFGKILLKvNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEP 315
Cdd:TIGR00914 240 APGQVQSMDDIRNIVIA-TGEGVPIRIRDVARVQIGKELRTGAATENGKEVVLGTVFMLIGENSRTVAQAVGDKLETINK 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 316 FFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTM 395
Cdd:TIGR00914 319 TLPEGVEIVTTYDRSQLVDAAIATVKKNLLEGALLVIVILFLFLGNIRAALIAATVIPLSLLITFIGMVFQGISANLMSL 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 396 fgMVLAIGLLVDDAIVVVENVERVMAE----EGLPPKEATR-----KSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAI 466
Cdd:TIGR00914 399 --GALDFGLIVDGAVVIVENAHRRLAEaqhhHGRQLTLKERlhevfAASREVRRPLIFGQLIITLVFLPIFTLTGVEGKM 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 467 YRQFSITIVSAMALSVLVALILTPALCATML-KPIAKGDHgegkkgffgWFNRMFEKSTHHYTDSVggiLRSTGRYLVLY 545
Cdd:TIGR00914 477 FHPMAFTVVLALAGAMILSLTFVPAAVALFIrGKVAEKEN---------RLMRVLKRRYEPLLERV---LAWPAVVLGAA 544
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 546 LIIVVGMAYLFVRLPSSFLPDEDQGVFMTM-VQLP------AGATQERTQKVLNEVTHyyltkeknnVESVFAVNGFGFA 618
Cdd:TIGR00914 545 AVSIVLVVWIASRVGGEFIPSLNEGDLAYQaLRIPgtslaqSVAMQQTLEKLIKSFPE---------VARVFAKTGTAEI 615
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 619 G------RGQNTGIAFVSLKDWadRPGE---ENKVEAITMRATRA------FSQ-IK---DAMVFAFNLPAIVELgtaTG 679
Cdd:TIGR00914 616 AtdpmppNASDTYIILKPESQW--PEGKktkEDLIEEIQEATVRIpgnnyeFTQpIQmrfNELISGVRSDVAVKV---FG 690
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 680 FDFELIDqaglghekltqARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYV 759
Cdd:TIGR00914 691 DDLDDLD-----------ATAEKISAVLKGVPGAADVKVEQTTGLPYLTVEIDREKAARYGLTVGDVQDTVATAVGGRMS 759
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 760 NDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYV-----RAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAApG 834
Cdd:TIGR00914 760 GETFEGDRRFDIVIRLPESLRESPQALRQLPIplplsEDARKQFIPLSDVADLRVSPGPNQISRENGKRRVVVSANVR-G 838
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 835 KSTGEAM-ELMEQLAS--KLPTGVGYDWTGmSYQERLSGNQAPSLYA-ISLIVVFLCLAALYESWSIPFSVMLVVPLGVI 910
Cdd:TIGR00914 839 RDLGSFVdDAKKAIAEqvKLPPGYWITWGG-QFEQLQSATKRLQIVVpVTLLLIFVLLYAAFGNVKDALLVFTGIPFALT 917
|
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 911 GALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDkEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLV 990
Cdd:TIGR00914 918 GGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFIRKLLE-EGPSLDEAVYEGALTRVRPVLMTALVASLGFVPMA 996
|
1050 1060
....*....|....*....|....*....
gi 16128446 991 ISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019
Cdd:TIGR00914 997 IATGTGAEVQRPLATVVIGGIITATLLTL 1025
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
277-1018 |
2.24e-21 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 100.32 E-value: 2.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 277 IIAEFNGQPASGLgiklatgANALDTAAAIRAELAKMEPffpSGLKIVY---PYDTTPFVKISIHEVVKTLVEAIILVFL 353
Cdd:COG1033 164 IVVTLDPDPLSSD-------LDRKEVVAEIRAIIAKYED---PGVEVYLtgfPVLRGDIAEAIQSDLAIFFPLALLLILL 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 354 VMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAeEGLPPKEATRK 433
Cdd:COG1033 234 LLFLFFRSLRGVLLPLLVVLLAVIWTLGLMGLLGIPLSPLTILVPPLLLAIGIDYGIHLLNRYREERR-KGLDKREALRE 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 434 SMGQiqgalVGIAMVLSAV-----FVPMAFfggSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG 508
Cdd:COG1033 313 ALRK-----LGPPVLLTSLttaigFLSLLF---SDIPPIRDFGIVAAIGVLLAFLTSLTLLPALLSLLPRPKPKTRRLKK 384
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 509 KKGFFGWFNRMFEKSTHHYTdsvggilrstgRYLVLYLIIVVGMAYLFVRLPSSFLPDEDqgvfmtmvqLPAGATQERTQ 588
Cdd:COG1033 385 PPELGRLLAKLARFVLRRPK-----------VILVVALVLAVVSLYGISRLKVEYDFEDY---------LPEDSPIRQDL 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 589 KVLNEVthyyltkeknnvesvfavngfgFAGrgqnTGIAFVSLKdwADRPGEENKVEaiTMRATRAFSQikdamvfafNL 668
Cdd:COG1033 445 DFIEEN----------------------FGG----SDPLEVVVD--TGEPDGLKDPE--VLKEIDRLQD---------YL 485
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 669 PAIVELGTATGFDfELIDQAglghekltqarNQLLAEaakhpdmltsvrpnglEDTPQFKIDIDQEKAQALgvsindinT 748
Cdd:COG1033 486 ESLPEVGKVLSLA-DLVKEL-----------NQALNE----------------GDPKYYALPESRELLAQL--------L 529
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 749 TLGAAWGGSYVNDFIDRgrvkkvyvmseakyrmlpddigdwyvraaDGQMVPFSAfsssrweygsprleRYNGLPSMEIL 828
Cdd:COG1033 530 LLLSSPPGDDLSRFVDE-----------------------------DYSAARVTV--------------RLKDLDSEEIK 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 829 GQAApgkstgeamELMEQLASKLPT-GVGYDWTGMSY-----QERLSGNQAPSLyAISLIVVFLCLAALYESWSIPFSVM 902
Cdd:COG1033 567 ALVE---------EVRAFLAENFPPdGVEVTLTGSAVlfaaiNESVIESQIRSL-LLALLLIFLLLLLAFRSLRLGLISL 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 903 L--VVPLGVIGALLAATfrgltnDVYFQVGLLT----TIGLSAKNAILIVEFAKDLMdKEGKGLIEATLDAVRMRLRPIL 976
Cdd:COG1033 637 IpnLLPILLTFGLMGLL------GIPLNIATAVvasiALGIGVDYTIHFLSRYREER-RKGGDLEEAIRRALRTTGKAIL 709
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 16128446 977 MTSLAFILGVMPLVIStgagsgaqNAVGTGVMGGMVTATVLA 1018
Cdd:COG1033 710 FTSLTLAAGFGVLLFS--------SFPPLADFGLLLALGLLV 743
|
|
| MMPL |
COG1033 |
Predicted exporter protein, RND superfamily [General function prediction only]; |
291-502 |
5.64e-18 |
|
Predicted exporter protein, RND superfamily [General function prediction only];
Pssm-ID: 440656 [Multi-domain] Cd Length: 767 Bit Score: 89.53 E-value: 5.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 291 IKLATGANALDTAAAIRAELAKMEP-----FFPSGLKIVYpYDTTPFVkisIHEVVKTLVEAIILVFLVMYLFLQNFRAT 365
Cdd:COG1033 557 LKDLDSEEIKALVEEVRAFLAENFPpdgveVTLTGSAVLF-AAINESV---IESQIRSLLLALLLIFLLLLLAFRSLRLG 632
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 366 LIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMaEEGLPPKEATRKSMGQIQGALVGI 445
Cdd:COG1033 633 LISLIPNLLPILLTFGLMGLLGIPLNIATAVVASIALGIGVDYTIHFLSRYREER-RKGGDLEEAIRRALRTTGKAILFT 711
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 16128446 446 AMVLSAVFVPMAFfggSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAK 502
Cdd:COG1033 712 SLTLAAGFGVLLF---SSFPPLADFGLLLALGLLVALLAALLLLPALLLLLDPRIAK 765
|
|
| YdfJ |
COG2409 |
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function ... |
289-593 |
8.36e-10 |
|
Predicted lipid transporter YdfJ, MMPL/SSD domain, RND superfamily [General function prediction only];
Pssm-ID: 441964 [Multi-domain] Cd Length: 697 Bit Score: 62.86 E-value: 8.36e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 289 LGIKLATGANALDTAAAIRAELAKMEPffpSGLKIVY---PYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRAT 365
Cdd:COG2409 120 VTLDGDAGDEAAEAVDALRDAVAAAPA---PGLTVYVtgpAALAADLNEAFEEDLGRAELITLPVALVVLLLVFRSLVAA 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 366 LIPTIAVPVVLLGTFAVLAAFG--FSINTLT-MFGMVLAIGLLVDDAIVVV----ENVERvmaeeGLPPKEATRKSMGQI 438
Cdd:COG2409 197 LLPLLTAGLAVGVALGLLALLAafTDVSSFApNLLTMLGLGVGIDYALFLVsryrEELRA-----GEDREEAVARAVATA 271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 439 Q------GALVGIAMvLSAVFVPMAFFggstgaiyRQFSITIVSAMALSVLVALILTPALCATM------LKPIAKGDHG 506
Cdd:COG2409 272 GravlfsGLTVAIAL-LGLLLAGLPFL--------RSMGPAAAIGVAVAVLAALTLLPALLALLgrrvfwPRRPRRRRAA 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 507 EGKKGFFGWFnrmfeksthhytdsVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFlPDEDqgvfmtmvQLPAGATQER 586
Cdd:COG2409 343 APESGFWRRL--------------ARAVVRRPVPVLVAAVAVLLALALPALGLRLGL-PDAD--------SLPADSPSRQ 399
|
....*..
gi 16128446 587 TQKVLNE 593
Cdd:COG2409 400 GYDALAE 406
|
|
| MMPL |
pfam03176 |
MMPL family; Members of this family are putative integral membrane proteins from bacteria. ... |
299-494 |
7.12e-09 |
|
MMPL family; Members of this family are putative integral membrane proteins from bacteria. Several of the members are mycobacterial proteins. Many of the proteins contain two copies of this aligned region. The function of these proteins is not known, although it has been suggested that they may be involved in lipid transport.
Pssm-ID: 308676 [Multi-domain] Cd Length: 332 Bit Score: 58.84 E-value: 7.12e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 299 ALDTAAAIRAELAKMEPffPSGLKIvypYDTTP------FVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAV 372
Cdd:pfam03176 102 ADESVAAVRDAVEQAPP--PEGLKA---YLTGPaatvadLRDAGDRDLGLIEAVTLVVIFIILLIVYRSVVAALLPLLTV 176
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 373 PVVLLGTFAVLAAF----GFSINTLT-MFGMVLAIGLLVDDAIVVvenVERVMAE--EGLPPKEATRKSMGQIQGALVGI 445
Cdd:pfam03176 177 GLSLGAAQGLVAILahilGIGLSTFAlNLLVVLLIAVGTDYALFL---VSRYREElrAGEDREEAVIRAVRGTGKVVTAA 253
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 16128446 446 AMVLSAVFVPMAFfggSTGAIYRQFSITIVSAMALSVLVALILTPALCA 494
Cdd:pfam03176 254 GLTVAIAMLALSF---ARLPVFAQVGPTIAIGVLVDVLAALTLLPALLA 299
|
|
| CusA |
COG3696 |
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism]; |
158-492 |
3.10e-08 |
|
Cu/Ag efflux pump CusA [Inorganic ion transport and metabolism];
Pssm-ID: 442911 [Multi-domain] Cd Length: 1031 Bit Score: 58.12 E-value: 3.10e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 158 VAANMKDAISRTSGVGDVQLF--GSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLggtppVKGQQ---LNA 232
Cdd:COG3696 690 LAEQIEAVLKTVPGAADVQVErvTGLPQLDIRIDRDAAARYGLNVADVQDVVETAIGGKAVGQV-----YEGERrfdIVV 764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 233 SIIAQTRlTSTEEFGKILLKVnQDGSRVLLRDVAKIELG-GENYdiIAEFNGQPasglgiKLATGANALD-----TAAAI 306
Cdd:COG3696 765 RLPEELR-DDPEAIRNLPIPT-PSGAQVPLSQVADIEVVeGPNQ--ISRENGRR------RIVVQANVRGrdlgsFVAEA 834
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 307 RAELAKMEPFfPSG------------------LKIVYPYdttpfvkisihevvktlveAIILVFLVMYLFLQNFRATLIP 368
Cdd:COG3696 835 QAKVAEQVKL-PPGyyiewggqfenlqratarLAIVVPL-------------------ALLLIFLLLYLAFGSVRDALLI 894
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 369 TIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMaEEGLPPKEATrksmgqIQGALVGI--- 445
Cdd:COG3696 895 LLNVPFALIGGVLALWLRGMPLSVSAGVGFIALFGVAVLNGVVLVSYINQLR-AEGLDLREAI------IEGALERLrpv 967
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 16128446 446 ---AMVLSAVFVPMAfFGGSTGA-IYRQFSITIVSAMALSVLVALILTPAL 492
Cdd:COG3696 968 lmtALVAALGLLPMA-LSTGPGSeVQRPLATVVIGGLITSTLLTLLVLPAL 1017
|
|
| secD |
TIGR01129 |
protein-export membrane protein SecD; Members of this family are highly variable in length ... |
269-492 |
2.43e-07 |
|
protein-export membrane protein SecD; Members of this family are highly variable in length immediately after the well-conserved motif LGLGLXGG at the amino-terminal end of this model. Archaeal homologs are not included in the seed and score between the trusted and noise cutoffs. SecD from Mycobacterium tuberculosis has a long Pro-rich insert. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273456 [Multi-domain] Cd Length: 397 Bit Score: 54.22 E-value: 2.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 269 ELGGENYDIIAEFNGQPASGLGIKLATGAnaldtaaairaelakmepfFPSGLKIVYPYDTTP-FVKISIHEVVKTLVEA 347
Cdd:TIGR01129 197 AITGGSGQITGNFTAEEANDLALVLRSGA-------------------LPAPLQILEERTIGPsLGADSIEAGIKAGLIG 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 348 IILVFLVMYLFLQNFraTLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAeEGLPP 427
Cdd:TIGR01129 258 LVLVLVFMILYYRLF--GLIAAIALVINIVLILAILSAFGATLTLPGIAGLILTIGMAVDANVLIYERIKEELR-LGKSV 334
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16128446 428 KEAT----RKSMGQIQGAlvGIAMVLSAVFvpMAFFGgsTGAIyRQFSITIVSAMALSVLVALILTPAL 492
Cdd:TIGR01129 335 RQAIeagfERAFSTIFDA--NITTLIAALI--LYVFG--TGPV-KGFAVTLAIGIIASLFTALVFTRLL 396
|
|
| 2A0601 |
TIGR00914 |
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation ... |
347-503 |
1.59e-06 |
|
heavy metal efflux pump, CzcA family; This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds]
Pssm-ID: 129992 [Multi-domain] Cd Length: 1051 Bit Score: 52.46 E-value: 1.59e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 347 AIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVeRVMAEEGLP 426
Cdd:TIGR00914 887 TLLLIFVLLYAAFGNVKDALLVFTGIPFALTGGVFALWLRGIPLSISAAVGFIALSGVAVLNGLVMISFI-RKLLEEGPS 965
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 427 PKEATrksmgqIQGALVGI------AMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPI 500
Cdd:TIGR00914 966 LDEAV------YEGALTRVrpvlmtALVASLGFVPMAIATGTGAEVQRPLATVVIGGIITATLLTLFVLPALYRLVHRRR 1039
|
...
gi 16128446 501 AKG 503
Cdd:TIGR00914 1040 HKG 1042
|
|
| COG4258 |
COG4258 |
Predicted exporter [General function prediction only]; |
347-491 |
4.35e-06 |
|
Predicted exporter [General function prediction only];
Pssm-ID: 443400 [Multi-domain] Cd Length: 783 Bit Score: 51.01 E-value: 4.35e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 347 AIILVFLVMYLFLQNFRATLIpTIAVPVV-LLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIvvvenverVMAEEGL 425
Cdd:COG4258 648 ALLLILLLLLLRLRSLRRALR-VLLPPLLaVLLTLAILGLLGIPLNLFHLIALLLVLGIGIDYAL--------FFTEGLL 718
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16128446 426 PPKEATRksmgqiqgALVGIAM-VLSAV--FVPMAFfgGSTGAIyRQFSITIVSAMALSVLVALILTPA 491
Cdd:COG4258 719 DKGELAR--------TLLSILLaALTTLlgFGLLAF--SSTPAL-RSFGLTVLLGILLALLLAPLLAPR 776
|
|
| SecD |
COG0342 |
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular ... |
336-492 |
6.72e-06 |
|
Preprotein translocase subunit SecD [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440111 [Multi-domain] Cd Length: 434 Bit Score: 49.73 E-value: 6.72e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 336 SIHEVVKTLVEAIILVFLVMYLFLQNFRatLIPTIAVPVVLLGTFAVLAAFGFsinTLTM---FGMVLAIGLLVDDaivv 412
Cdd:COG0342 269 SIEKGLIAGLIGLLLVALFMLLYYRLPG--LVANIALALNVVLLLGVLSLLGA---TLTLpgiAGIILTIGMAVDA---- 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 413 veNV---ERVMAE--EGLPPKEAT----RKSMGQIQGALV--GIAMvlsavfVPMAFFGgsTGAIyRQFSITIVSAMALS 481
Cdd:COG0342 340 --NVlifERIREElrAGRSLRAAIeagfKRAFSTILDANVttLIAA------VVLFVLG--TGPV-KGFAVTLILGILIS 408
|
170
....*....|.
gi 16128446 482 VLVALILTPAL 492
Cdd:COG0342 409 MFTAVPVTRPL 419
|
|
| 2A067 |
TIGR00921 |
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized ... |
317-492 |
1.03e-05 |
|
The (Largely Archaeal Putative) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; Characterized members of the RND superfamily all probably catalyze substrate efflux via an H+ antiport mechanism. These proteins are found ubiquitously in bacteria, archaea and eukaryotes. They fall into seven phylogenetic families, this family (2.A.6.7) consists of uncharacterised putative transporters, largely in the Archaea. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 273340 [Multi-domain] Cd Length: 719 Bit Score: 49.45 E-value: 1.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 317 FPSGLKIVY---PYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPtiaVPVVLLGTFAVLAAFG-----F 388
Cdd:TIGR00921 169 PPSGKFLDVtgsPAINYDIEREFGKDMGTTMAISGILVVLVLLLDFKRWWRPLLP---LVIILFGVAWVLGIMGwlgipL 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 389 SINTLTMFGMVLAIGLlvdDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFfggSTGAIYR 468
Cdd:TIGR00921 246 YATTLLAVPMLIGVGI---DYGIQTLNRYEEERDIGRAKGEAIVTAVRRTGRAVLIALLTTSAGFAALAL---SEFPMVS 319
|
170 180
....*....|....*....|....
gi 16128446 469 QFSITIVSAMALSVLVALILTPAL 492
Cdd:TIGR00921 320 EFGLGLVAGLITAYLLTLLVLPAL 343
|
|
| Patched |
pfam02460 |
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic ... |
341-492 |
5.86e-05 |
|
Patched family; The transmembrane protein Patched is a receptor for the morphogene Sonic Hedgehog. This protein associates with the smoothened protein to transduce hedgehog signals.
Pssm-ID: 308203 [Multi-domain] Cd Length: 793 Bit Score: 47.35 E-value: 5.86e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 341 VKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERvm 420
Cdd:pfam02460 642 IQNIVITLICMFIVCFLFIPNPPCVFVITLAIASIDIGVFGFLSLWGVDLDPISMITIIMSIGFSVDFSAHIAYHFVR-- 719
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16128446 421 aEEGLPPKEATRKSMGQI-----QGALVGIAMVLSAVFVPmaffggsTGAIyRQFSITIVSAMALSVLVALILTPAL 492
Cdd:pfam02460 720 -SRGDTPAERVVDALEALgwpvfQGGLSTILGVLVLLFVP-------SYMV-VVFFKTVFLVVAIGLLHGLFILPII 787
|
|
| PRK13024 |
PRK13024 |
bifunctional preprotein translocase subunit SecD/SecF; Reviewed |
336-558 |
1.52e-04 |
|
bifunctional preprotein translocase subunit SecD/SecF; Reviewed
Pssm-ID: 237276 [Multi-domain] Cd Length: 755 Bit Score: 45.99 E-value: 1.52e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 336 SIHEVVKTLVEAIILVFLVMYLFLQnfRATLIPTIAVPVVLLGTFAVLAAFGFsinTLTM---FGMVLAIGLLVDDAIVV 412
Cdd:PRK13024 264 AIDAGIIAGIIGFALIFLFMLVYYG--LPGLIANIALLLYIFLTLGALSSLGA---VLTLpgiAGLVLGIGMAVDANVLI 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 413 VENVErvmaEE---GLPPKEATRKSMgqiQGALVGIA-----MVLSAV--FvpmaFFGgsTGAIyRQFSITIVSAMALSV 482
Cdd:PRK13024 339 FERIK----EElrkGKSLKKAFKKGF---KNAFSTILdsnitTLIAAAilF----FFG--TGPV-KGFATTLIIGILASL 404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 483 LVALILTPALCATMLKpiakgdHGEGKKGFFG----WFNRMFEKSTHHYT-DSVGgilRSTGRYLVLYLIIVVGMAYLFV 557
Cdd:PRK13024 405 FTAVFLTRLLLELLVK------RGDKKPFLFGvkkkKIHNINEGVTIFDRiDFVK---KRKWFLIFSIVLVIAGIIIFFI 475
|
.
gi 16128446 558 R 558
Cdd:PRK13024 476 F 476
|
|
| PRK10614 |
PRK10614 |
multidrug efflux system subunit MdtC; Provisional |
286-490 |
3.67e-04 |
|
multidrug efflux system subunit MdtC; Provisional
Pssm-ID: 182589 [Multi-domain] Cd Length: 1025 Bit Score: 44.72 E-value: 3.67e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 286 ASGLGIKLATGANALDTAAAIraELAKMEPFFPSGLKIVYPYDTTPFVKiSIHEVVKTLVEAIILVFLVMYLFLQNFRAT 365
Cdd:PRK10614 801 ASTISFNLPTGKSLSDASAAI--ERAMTQLGVPSTVRGSFAGTAQVFQE-TMNSQLILILAAIATVYIVLGILYESYVHP 877
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 366 LIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATrksmgqIQGALV-- 443
Cdd:PRK10614 878 LTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRNGNLTAQEAI------FQACLLrf 951
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 16128446 444 -GIAMV-LSAVF--VPMAFFGGStGAIYRQ-FSITIVSAMALSVLVALILTP 490
Cdd:PRK10614 952 rPIMMTtLAALFgaLPLVLSGGD-GAELRQpLGITIVGGLVMSQLLTLYTTP 1002
|
|
| 2A0604s01 |
TIGR00916 |
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY ... |
336-486 |
3.98e-04 |
|
protein-export membrane protein, SecD/SecF family; The SecA,SecB,SecD,SecE,SecF,SecG and SecY proteins form the protein translocation appartus in prokaryotes. This family is specific for the SecD and SecF proteins. [Protein fate, Protein and peptide secretion and trafficking]
Pssm-ID: 273336 [Multi-domain] Cd Length: 192 Bit Score: 42.63 E-value: 3.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 336 SIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLgTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVEN 415
Cdd:TIGR00916 45 LIKAGIIALLIGLVLVLLYMLLRYEWRGAIAAIAALVHDVIL-ILGVLSLFGATLTLPGIAGLLTIIGYSVDDTVVIFDR 123
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128446 416 V-ERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGstGAIyRQFSITIVSAMALSVLVAL 486
Cdd:TIGR00916 124 IrEELRKYKGRTFREAINLGINQTLSRIIDTNVTTLLAVLALYVFGG--GAI-KGFALTLGIGVIAGTYSSI 192
|
|
| HpnN |
TIGR03480 |
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing ... |
336-502 |
9.17e-03 |
|
hopanoid biosynthesis associated RND transporter like protein HpnN; The genomes containing members of this family share the machinery for the biosynthesis of hopanoid lipids. Furthermore, the genes of this family are usually located proximal to other components of this biological process. The proteins appear to be related to the RND family of export proteins, particularly the hydrophobe/amphiphile efflux-3 (HAE3) family represented by TIGR00921.
Pssm-ID: 274598 [Multi-domain] Cd Length: 862 Bit Score: 39.98 E-value: 9.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 336 SIHEVVKTLVEAIILVFLVMYLFLQNFR---ATLIPTIavpVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVV 412
Cdd:TIGR03480 267 VSEGATVAGLLSFVLVLVLLWLALRSPRlvfAVLVTLI---VGLILTAAFATLAVGHLNLISVAFAVLFIGLGVDFAIQF 343
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128446 413 VENVeRVMAEEGLPPKEATRKSMGQIQGALVgIAMVLSAV----FVPMAFFGGStgaiyrQFSITIVSAMALSVLVALIL 488
Cdd:TIGR03480 344 SLRY-REERFRGGNHREALSVAARRMGAALL-LAALATAAgffaFLPTDYKGVS------ELGIIAGTGMFIALFVTLTV 415
|
170
....*....|....
gi 16128446 489 TPALCaTMLKPIAK 502
Cdd:TIGR03480 416 LPALL-RLLRPPRR 428
|
|
| |
