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Conserved domains on  [gi|16128829|ref|NP_415382|]
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L-arginine ABC transporter membrane subunit ArtM [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

arginine ABC transporter permease ArtM( domain architecture ID 11485213)

arginine ABC transporter permease ArtM is part of the ABC transporter complex ArtPIQMJ involved in arginine transport

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
artM PRK11122
arginine ABC transporter permease ArtM;
1-222 3.90e-146

arginine ABC transporter permease ArtM;


:

Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 405.88  E-value: 3.90e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    1 MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY 80
Cdd:PRK11122   1 MLEYLPELLKGLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPWLQEY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   81 PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK 160
Cdd:PRK11122  81 PWLWHLLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLRILLPYAFKRALSSYSNEVVLVFK 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128829  161 STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN 222
Cdd:PRK11122 161 STSLAYTITLMDVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLLMRLIERKALAFERRN 222
 
Name Accession Description Interval E-value
artM PRK11122
arginine ABC transporter permease ArtM;
1-222 3.90e-146

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 405.88  E-value: 3.90e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    1 MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY 80
Cdd:PRK11122   1 MLEYLPELLKGLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPWLQEY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   81 PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK 160
Cdd:PRK11122  81 PWLWHLLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLRILLPYAFKRALSSYSNEVVLVFK 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128829  161 STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN 222
Cdd:PRK11122 161 STSLAYTITLMDVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLLMRLIERKALAFERRN 222
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 1-222 6.21e-99

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 286.61  E-value: 6.21e-99
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   1 MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY 80
Cdd:COG4160   6 LFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGQFEWVRES 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829  81 PaLWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLA-ILLPYAFKRSLSSYSNEVVLVF 159
Cdd:COG4160  86 W-LWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRrIILPSALRRALPAYSNEVILML 164

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16128829 160 KSTSLAYTITLMEVMGYSQLLYGRTYDVM-VFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN 222
Cdd:COG4160 165 KATALASTITVMDLTGVARRIYSRTYDPFePFLIAALIYLVITFLLTRLFRLLERRLLRHLRPR 228
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 5-214 7.68e-22

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 89.14  E-value: 7.68e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829     5 LPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTlqEYPALw 84
Cdd:TIGR03003  10 LPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDIGI--RLPAL- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    85 hllsepwLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDT-LAILLPYAFKRSLSSYSNEVVLVFKSTS 163
Cdd:TIGR03003  87 -------VAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTyRHIILPQAIPPIIPALGNYLVAMFKETP 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 16128829   164 LAYTITLMEVMGYSQLLYGRTYDVMV-FGAAGIIYLVVNGLLTLMMRLIERK 214
Cdd:TIGR03003 160 VLSAITVLELMNQAKSIGNSTFRYLEpMTLVGVFFLILSIISVFFLRRLEAR 211
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 15-206 5.07e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.39  E-value: 5.07e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829  15 SLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTlqeypalWHLLSEPWLCA 94
Cdd:cd06261   4 TLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG-------WGILPGLGLPA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829  95 LIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTL-AILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEV 173
Cdd:cd06261  77 LILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFrRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEA 156

                       170       180       190
                ....*....|....*....|....*....|....
gi 16128829 174 MGYSQLLYG-RTYDVMVFGAAGIIYLVVNGLLTL 206
Cdd:cd06261 157 PGPGTGLLLiFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 46-214 3.06e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 43.06  E-value: 3.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    46 WLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQeypalwhllsePWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSC 125
Cdd:pfam00528  18 RLLRPLIDLLQALPSFVLAILLVVIAILSILGH-----------GILPAIILALLGWAGYARLIRRAALRSLPSDLVEAA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   126 SALGMSKKDTLA-ILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGY----SQLLYGRTYDVMVFGAAGIIYLVV 200
Cdd:pfam00528  87 RALGASRWQIFRkIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLllieAILGYDYPEIQGPVLAAALILLLL 166

                         170
                  ....*....|....
gi 16128829   201 NGLLTLMMRLIERK 214
Cdd:pfam00528 167 NLLVDILQRLLDPR 180
 
Name Accession Description Interval E-value
artM PRK11122
arginine ABC transporter permease ArtM;
1-222 3.90e-146

arginine ABC transporter permease ArtM;


Pssm-ID: 182978 [Multi-domain]  Cd Length: 222  Bit Score: 405.88  E-value: 3.90e-146
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    1 MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY 80
Cdd:PRK11122   1 MLEYLPELLKGLHTSLTLTVASLLVALVLALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPWLQEY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   81 PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK 160
Cdd:PRK11122  81 PWLWHLLSQPWLCAMLALALNSAAYSTQLFYGAVRAIPEGQWQSCAALGMSKKQTLRILLPYAFKRALSSYSNEVVLVFK 160

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16128829  161 STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN 222
Cdd:PRK11122 161 STSLAYTITLMDVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLLMRLIERKALAFERRN 222
ArtM COG4160
ABC-type arginine/histidine transport system, permease component [Amino acid transport and ...
 1-222 6.21e-99

ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 443325 [Multi-domain]  Cd Length: 229  Bit Score: 286.61  E-value: 6.21e-99
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   1 MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY 80
Cdd:COG4160   6 LFEYLPLLLSGLPLTLQLLALSLLLGFLLAVPLALARASGNRLLRWPARGYIYVFRGTPLLVQLFLIYYGLGQFEWVRES 85

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829  81 PaLWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLA-ILLPYAFKRSLSSYSNEVVLVF 159
Cdd:COG4160  86 W-LWPLLRDPWFCALLALTLNTAAYTAEIFRGAIRAVPKGEIEAARALGMSRWQTFRrIILPSALRRALPAYSNEVILML 164

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16128829 160 KSTSLAYTITLMEVMGYSQLLYGRTYDVM-VFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN 222
Cdd:COG4160 165 KATALASTITVMDLTGVARRIYSRTYDPFePFLIAALIYLVITFLLTRLFRLLERRLLRHLRPR 228
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 1-214 2.38e-55

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 175.65  E-value: 2.38e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   1 MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGpgqfptlqeY 80
Cdd:COG0765   8 LLDYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIYFG---------L 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829  81 PALWHLLSePWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLA-ILLPYAFKRSLSSYSNEVVLVF 159
Cdd:COG0765  79 PLLGIDLS-PFVAAVIALTLNSAAYLAEIVRAGIQSVPKGQWEAARALGLSRWQTMRrIILPQALRIILPPLGNEFISLL 157

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 16128829 160 KSTSLAYTITLMEVMGYSQLLYGRTYDVM-VFGAAGIIYLVVNGLLTLMMRLIERK 214
Cdd:COG0765 158 KDTSLVSVIGVPELTRAAQQIASRTFRPFeVYLVAALIYLVLTLPLSLLARRLERR 213
PRK15069 PRK15069
histidine ABC transporter permease HisM;
9-218 1.44e-36

histidine ABC transporter permease HisM;


Pssm-ID: 185029 [Multi-domain]  Cd Length: 234  Bit Score: 128.24  E-value: 1.44e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    9 MKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLS 88
Cdd:PRK15069  20 FTGLAITLWLLVASVVIGFVLAVPLAIARVSSNKWIRFPVWLYTYVFRGTPLYVQLLVFYTGMYSLEIVRGTDLLDAFFR 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   89 EPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSK-KDTLAILLPYAFKRSLSSYSNEVVLVFKSTSLAYT 167
Cdd:PRK15069 100 SGLNCTILAFTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGMSTfKLYRRIILPSALRRALPAYSNEVILMLHATTLAFT 179

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 16128829  168 ITLMEVMGYSQLLYGRTYDVM-VFGAAGIIYLVVNGLLTLMMRLIERKALAF 218
Cdd:PRK15069 180 ATVPDILKIARDINSATYQPFqAFGIAAVLYLIISFVLISLFRRAERRWLAH 231
PRK15100 PRK15100
cystine ABC transporter permease;
5-215 1.18e-33

cystine ABC transporter permease;


Pssm-ID: 185055 [Multi-domain]  Cd Length: 220  Bit Score: 120.24  E-value: 1.18e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    5 LPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFptlqeypalw 84
Cdd:PRK15100  12 APFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYVSIFRGTPLIAQLFMIYYGLPQF---------- 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   85 HLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTL-AILLPYAFKRSLSSYSNEVVLVFKSTS 163
Cdd:PRK15100  82 GIELDPIPAAMIGLSLNTAAYAAETLRAAISSIDKGQWEAAASIGMTRWQTLrRAILPQAARTALPPLSNSFISLVKDTS 161

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 16128829  164 LAYTITLMEVMGYSQLLYGRTYDVM-VFGAAGIIYLVVNGLLTLMMRLIERKA 215
Cdd:PRK15100 162 LAATIQVPELFRQAQLITSRTLEVFtMYLAASLIYWIMATVLSALQNRFENQL 214
PRK11123 PRK11123
arginine ABC transporter permease ArtQ;
1-222 5.36e-33

arginine ABC transporter permease ArtQ;


Pssm-ID: 182979 [Multi-domain]  Cd Length: 238  Bit Score: 119.01  E-value: 5.36e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    1 MFEYLPeLMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQ------- 73
Cdd:PRK11123   1 MNEFFP-LASAAGMTVGLAVCALIVGLALAMLFAVWESAKWRPVAWPGTALVTLLRGLPEILVVLFIYFGSSQllltlsd 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   74 -------FPTLQEYPALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDT-LAILLPYAFK 145
Cdd:PRK11123  80 gftlnlgFVQIPVQMDIENFEVSPFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIfFRLVMPQMWR 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16128829  146 RSLSSYSNEVVLVFKSTSLAYTITLMEVMGYSQLLYGRTYDVMV-FGAAGIIYLVVNGLLTLMMRLIERKALAFERRN 222
Cdd:PRK11123 160 HALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTwYIIAAAIYLVITLISQYILKRIELRATRFERRP 237
glnP PRK09494
glutamine ABC transporter permease protein; Reviewed
 5-214 3.68e-22

glutamine ABC transporter permease protein; Reviewed


Pssm-ID: 181907 [Multi-domain]  Cd Length: 219  Bit Score: 90.11  E-value: 3.68e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    5 LPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGpgqFPTLqeypaLW 84
Cdd:PRK09494  12 IPLLLEGAKMTLWISVLGLAGGLVIGLLAGFARAYGGWIANHIALVFIELIRGTPIVVQVMFIYFA---LPMA-----FN 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   85 HLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLA-ILLPYAFKRSLSSYSNEVVLVFKSTS 163
Cdd:PRK09494  84 DLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRRETLRyVIGPLALRRMLPPLGNQWIISIKDTS 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 16128829  164 LAYTITLMEVMGYSQ-LLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERK 214
Cdd:PRK09494 164 LFIVIGVAELTRQGQeIIAGNFRALEIWSAVAVIYLIITLVLSFILRRLERR 215
ectoine_ehuD TIGR03003
ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are ...
 5-214 7.68e-22

ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Members of this family are presumed to act as permease subunits of ectoine ABC transporters. Operons containing this gene also contain the other genes of the ABC transporter and typically are found next to either ectoine utilization or ectoine biosynthesis operons.


Pssm-ID: 132048 [Multi-domain]  Cd Length: 212  Bit Score: 89.14  E-value: 7.68e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829     5 LPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTlqEYPALw 84
Cdd:TIGR03003  10 LPTLIEGLKITILATALGFAIAAVLGLVFAILRRSAPTPISWPTSFVVEFIRGTPLLVQLYFLYYVLPDIGI--RLPAL- 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    85 hllsepwLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDT-LAILLPYAFKRSLSSYSNEVVLVFKSTS 163
Cdd:TIGR03003  87 -------VAGVLGLGLHYATYAAEVYRAGIEAVPRGQWEAATALNLTARQTyRHIILPQAIPPIIPALGNYLVAMFKETP 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 16128829   164 LAYTITLMEVMGYSQLLYGRTYDVMV-FGAAGIIYLVVNGLLTLMMRLIERK 214
Cdd:TIGR03003 160 VLSAITVLELMNQAKSIGNSTFRYLEpMTLVGVFFLILSIISVFFLRRLEAR 211
HEQRo_perm_3TM TIGR01726
amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This ...
 4-112 3.71e-16

amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; This model represents one of several classes of multiple membrane spanning regions found immediately N-terminal to the domain described by pfam00528, binding-protein-dependent transport systems inner membrane component. The region covered by this model generally is predicted to contain three transmembrane helices. Substrate specificities attributed to members of this family include histidine, arginine, glutamine, glutamate, and (in Agrobacterium) the opines octopine and nopaline. [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 130787 [Multi-domain]  Cd Length: 99  Bit Score: 71.02  E-value: 3.71e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829     4 YLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFptlqeypal 83
Cdd:TIGR01726   1 NLPFLLKGLLLTLLLSVLSILLGLVLGLLLALLRLSGNRPLRWIATVYVELFRGTPLLVQLFFIYFGLPLI--------- 71

                          90       100
                  ....*....|....*....|....*....
gi 16128829    84 wHLLSEPWLCALIALSLNSAAYTTQLFYG 112
Cdd:TIGR01726  72 -GIRLSPLTAAVIALTLFYGAYLAEIFRG 99
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 15-206 5.07e-15

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 70.39  E-value: 5.07e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829  15 SLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTlqeypalWHLLSEPWLCA 94
Cdd:cd06261   4 TLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLG-------WGILPGLGLPA 76

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829  95 LIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTL-AILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEV 173
Cdd:cd06261  77 LILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFrRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEA 156

                       170       180       190
                ....*....|....*....|....*....|....
gi 16128829 174 MGYSQLLYG-RTYDVMVFGAAGIIYLVVNGLLTL 206
Cdd:cd06261 157 PGPGTGLLLiFAILFPGDLGVAAAVALILLLLSL 190
PRK15135 PRK15135
histidine ABC transporter permease HisQ;
8-214 3.38e-13

histidine ABC transporter permease HisQ;


Pssm-ID: 185089 [Multi-domain]  Cd Length: 228  Bit Score: 66.36  E-value: 3.38e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    8 LMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPG-QFPTLQEYPALWHL 86
Cdd:PRK15135   9 ILQGALVTLELALSSVVLAVIIGLIGAGGKLSQNRLLGLIFEGYTTLIRGVPDLVLMLLIFYGLQiALNSVTEALGVGQI 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   87 LSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTL-AILLPYAFKRSLSSYSNEVVLVFKSTSLA 165
Cdd:PRK15135  89 DIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFrRIMFPAMMRYALPGIGNNWQVILKATALV 168

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 16128829  166 YTITLMEVMGYSQLLYGRTYDVMVFG-AAGIIYLVVNGLLTLMMRLIERK 214
Cdd:PRK15135 169 SLLGLEDVVKATQLAGKSTWEPFYFAiVCGVIYLVFTTVSNGVLLWLERR 218
PRK15107 PRK15107
glutamate/aspartate ABC transporter permease GltK;
5-170 1.49e-09

glutamate/aspartate ABC transporter permease GltK;


Pssm-ID: 185062 [Multi-domain]  Cd Length: 224  Bit Score: 55.99  E-value: 1.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    5 LPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFptLQEYPALW 84
Cdd:PRK15107  13 LPYLLDGLVITLKITVTAVVIGILWGTILAVMRLSSFKPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGF--LQNVLGLS 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   85 HLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLA-ILLPYAFKRSLSSYSNEVVLVFKSTS 163
Cdd:PRK15107  91 PKTDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKlIILPQAFRAMVPLLLTQGIVLFQDTS 170


                 ....*..
gi 16128829  164 LAYTITL 170
Cdd:PRK15107 171 LVYVLSL 177
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 46-214 3.06e-05

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 43.06  E-value: 3.06e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829    46 WLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQeypalwhllsePWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSC 125
Cdd:pfam00528  18 RLLRPLIDLLQALPSFVLAILLVVIAILSILGH-----------GILPAIILALLGWAGYARLIRRAALRSLPSDLVEAA 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   126 SALGMSKKDTLA-ILLPYAFKRSLSSYSNEVVLVFKSTSLAYTITLMEVMGY----SQLLYGRTYDVMVFGAAGIIYLVV 200
Cdd:pfam00528  87 RALGASRWQIFRkIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGLllieAILGYDYPEIQGPVLAAALILLLL 166

                         170
                  ....*....|....
gi 16128829   201 NGLLTLMMRLIERK 214
Cdd:pfam00528 167 NLLVDILQRLLDPR 180
PhnE COG3639
ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport ...
 2-132 1.44e-04

ABC-type phosphate/phosphonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 442856 [Multi-domain]  Cd Length: 244  Bit Score: 41.60  E-value: 1.44e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16128829   2 FEYLPELMKGLHTSLTLTVASLIVALILALIFTII---LTLKTPVLVWLVRGYITLFTGTPLLV--QIFLIYYGPGQFPt 76
Cdd:COG3639  43 WSYLPDLLSALLETLAIALLGTLLGAVLALPLAFLaarNLAPNPWVRLLARRLLNVLRAIPELVwaLIFVAAVGLGPFA- 121

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 16128829  77 lqeypalwhllsepwlcALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSK 132
Cdd:COG3639 122 -----------------GVLALAIHTIGFLGKLFAEAIEEIDPGPVEALRATGASR 160
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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