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Conserved domains on  [gi|16129062|ref|NP_415617|]
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DNA polymerase III subunit delta' [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

DNA polymerase III subunit delta'( domain architecture ID 11483015)

DNA polymerase III subunit delta' interacts with the delta and gamma subunits and is part of the clamp-loading complex, which assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 1-334 0e+00

DNA polymerase III subunit delta'; Validated


:

Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 591.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    1 MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLA 80
Cdd:PRK07993   1 MKWYPWLRPDYEQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   81 PEKGKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK07993  81 PEKGKSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  161 LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQALAYSVPSGDWYSLLAALNHEQ 240
Cdd:PRK07993 161 LHYLAPPPEQYALTWLSREVTMSQDALLAALRLSAGAPGAALALLQPERWQQREALCQALAYALPSGDWLSLLPALNHEQ 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  241 APARLHWLATLLMDALKRHHGAAQVTNVDVPGLVAELANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIE 320
Cdd:PRK07993 241 APARLHWLATLLMDALKRQHGAAYVTNQDQPPLVAQLANHLSPARLQAILGDVCHCREQLLSVTGVNRELLLTDLLLRIE 320

                        330
                 ....*....|....
gi 16129062  321 HYLQPGVVLPVPHL 334
Cdd:PRK07993 321 HYLQPGTVLPVPHL 334
 
Name Accession Description Interval E-value
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 1-334 0e+00

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 591.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    1 MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLA 80
Cdd:PRK07993   1 MKWYPWLRPDYEQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   81 PEKGKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK07993  81 PEKGKSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  161 LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQALAYSVPSGDWYSLLAALNHEQ 240
Cdd:PRK07993 161 LHYLAPPPEQYALTWLSREVTMSQDALLAALRLSAGAPGAALALLQPERWQQREALCQALAYALPSGDWLSLLPALNHEQ 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  241 APARLHWLATLLMDALKRHHGAAQVTNVDVPGLVAELANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIE 320
Cdd:PRK07993 241 APARLHWLATLLMDALKRQHGAAYVTNQDQPPLVAQLANHLSPARLQAILGDVCHCREQLLSVTGVNRELLLTDLLLRIE 320

                        330
                 ....*....|....
gi 16129062  321 HYLQPGVVLPVPHL 334
Cdd:PRK07993 321 HYLQPGTVLPVPHL 334
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
7-321 2.18e-79

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 243.73  E-value: 2.18e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   7 LRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRgCQLMQAGTHPDYYTLAPEKGKN 86
Cdd:COG0470   1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELNPEEKSD 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  87 TLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAP 166
Cdd:COG0470  80 QIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062 167 PPEQYAVTWLSREvTMSQDALLAALRLSAGSPGAALALFQGdnWQARETLCQALAYSVPSGDWYSLLAALNHEQAPARLH 246
Cdd:COG0470 160 PSEEEALAWLREE-GVDEDALEAILRLAGGDPRAAINLLQA--LAGRKELLEDLAALLSRDRALELLDALLKAEALELLD 236

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16129062 247 WLATLLMDALKRhhgaaqvtnvdvpglvaelanHLSPSRLQAILGDVCHIREQLMSvtGINRELLITDLLLRIEH 321
Cdd:COG0470 237 WLLKWLLDNLPL---------------------EYAGEDLARAYEALSEADRRLGR--YANDRLLLEALLAKLGR 288
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 14-201 1.01e-52

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 172.04  E-value: 1.01e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    14 LVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKntLGVDAV 93
Cdd:TIGR00678   4 LKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQS--IKVDQV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    94 REVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAPPPEQYAV 173
Cdd:TIGR00678  82 RELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALL 161

                         170       180
                  ....*....|....*....|....*...
gi 16129062   174 TWLSREvTMSQDALLAALRLSAGSPGAA 201
Cdd:TIGR00678 162 QWLIRQ-GISEEAAELLLALAGGSPGRA 188
DNApol3-delta_C pfam09115
DNA polymerase III, delta subunit, C terminal; Members of this family, which are predominantly ...
 210-319 3.40e-38

DNA polymerase III, delta subunit, C terminal; Members of this family, which are predominantly found in prokaryotic DNA polymerase III, assume an alpha helical structure, with a core of five alpha helices, and an additional small helix. They are essential for the formation of the polymerase clamp loader.


Pssm-ID: 430418 [Multi-domain]  Cd Length: 112  Bit Score: 131.60  E-value: 3.40e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   210 WQARETLCQAL-AYSVPSGDWYSLLAALNHEQAPARLHWLATLLMDALKRHHGAA-QVTNVDVPGLVAELANHLSPSRLQ 287
Cdd:pfam09115   1 WQARKALLQALvALALQRGDLLSLLPLLNKDDALVRLHWLSSLLLDALKYQQGVQdQLVNQDQIALIAQLAQRLSAERLL 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 16129062   288 AILGDVCHIREQLMSVTGINRELLITDLLLRI 319
Cdd:pfam09115  81 AQLQKLLECREQLLSIPGVNRELLLTEWLLRW 112
 
Name Accession Description Interval E-value
PRK07993 PRK07993
DNA polymerase III subunit delta'; Validated
 1-334 0e+00

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181190 [Multi-domain]  Cd Length: 334  Bit Score: 591.27  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    1 MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLA 80
Cdd:PRK07993   1 MKWYPWLRPDYEQLVGSYQAGRGHHALLIQALPGMGDDALIYALSRWLMCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   81 PEKGKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK07993  81 PEKGKSSLGVDAVREVTEKLYEHARLGGAKVVWLPDAALLTDAAANALLKTLEEPPENTWFFLACREPARLLATLRSRCR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  161 LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQALAYSVPSGDWYSLLAALNHEQ 240
Cdd:PRK07993 161 LHYLAPPPEQYALTWLSREVTMSQDALLAALRLSAGAPGAALALLQPERWQQREALCQALAYALPSGDWLSLLPALNHEQ 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  241 APARLHWLATLLMDALKRHHGAAQVTNVDVPGLVAELANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIE 320
Cdd:PRK07993 241 APARLHWLATLLMDALKRQHGAAYVTNQDQPPLVAQLANHLSPARLQAILGDVCHCREQLLSVTGVNRELLLTDLLLRIE 320

                        330
                 ....*....|....
gi 16129062  321 HYLQPGVVLPVPHL 334
Cdd:PRK07993 321 HYLQPGTVLPVPHL 334
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
7-321 2.18e-79

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 243.73  E-value: 2.18e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   7 LRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRgCQLMQAGTHPDYYTLAPEKGKN 86
Cdd:COG0470   1 QEEAWEQLLAAAESGRLPHALLLHGPPGIGKTTLALALARDLLCENPEGGKACGQCH-SRLMAAGNHPDLLELNPEEKSD 79

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  87 TLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAP 166
Cdd:COG0470  80 QIGIDQIRELGEFLSLTPLEGGRKVVIIDEADAMNEAAANALLKTLEEPPKNTPFILIANDPSRLLPTIRSRCQVIRFRP 159

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062 167 PPEQYAVTWLSREvTMSQDALLAALRLSAGSPGAALALFQGdnWQARETLCQALAYSVPSGDWYSLLAALNHEQAPARLH 246
Cdd:COG0470 160 PSEEEALAWLREE-GVDEDALEAILRLAGGDPRAAINLLQA--LAGRKELLEDLAALLSRDRALELLDALLKAEALELLD 236

                       250       260       270       280       290       300       310
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16129062 247 WLATLLMDALKRhhgaaqvtnvdvpglvaelanHLSPSRLQAILGDVCHIREQLMSvtGINRELLITDLLLRIEH 321
Cdd:COG0470 237 WLLKWLLDNLPL---------------------EYAGEDLARAYEALSEADRRLGR--YANDRLLLEALLAKLGR 288
PRK06871 PRK06871
DNA polymerase III subunit delta'; Validated
 1-319 9.16e-68

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180738 [Multi-domain]  Cd Length: 325  Bit Score: 215.37  E-value: 9.16e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    1 MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLA 80
Cdd:PRK06871   1 MALYPWLQPTYQQITQAFQQGLGHHALLFKADSGLGTEQLIRALAQWLMCQTPQGDQPCGQCHSCHLFQAGNHPDFHILE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   81 PEKGKNtLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK06871  81 PIDNKD-IGVDQVREINEKVSQHAQQGGNKVVYIQGAERLTEAAANALLKTLEEPRPNTYFLLQADLSAALLPTIYSRCQ 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  161 LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQALAYSVPSGDWYSLLAALNHEQ 240
Cdd:PRK06871 160 TWLIHPPEEQQALDWLQAQSSAEISEILTALRINYGRPLLALTFLEQGLLEQRKTFLRQFWLFYRRRSPLELLPLFDKEL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  241 APARLHWLATLLMDALKRHHGAAQ-VTNVDVPGLVAELANHLS-PSRLQA--ILGDVchiREQLMSVTGINRELLITDLL 316
Cdd:PRK06871 240 VLQQLDWLLAFLSDALKAKLDIASgWICQDLQRGILQFSQQQSaQGLLKAhqIIQKV---RSDLLQINAVNQELILLDGL 316


                 ...
gi 16129062  317 LRI 319
Cdd:PRK06871 317 TRL 319
PRK05707 PRK05707
DNA polymerase III subunit delta'; Validated
 4-318 9.22e-53

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180215 [Multi-domain]  Cd Length: 328  Bit Score: 176.43  E-value: 9.22e-53
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    4 YPWLRPDFEKLVASyqaGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEK 83
Cdd:PRK05707   5 YPWQQSLWQQLAGR---GRHPHAYLLHGPAGIGKRALAERLAAALLCEAPQGGGACGSCKGCQLLRAGSHPDNFVLEPEE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   84 GKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHY 163
Cdd:PRK05707  82 ADKTIKVDQVRELVSFVVQTAQLGGRKVVLIEPAEAMNRNAANALLKSLEEPSGDTVLLLISHQPSRLLPTIKSRCQQQA 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  164 LAPPPEQYAVTWLSREVTMS-QDALLAALRLSAGSPGAALALfQGDNWQARETLCQALAYSVPSG--DWYSLLAALNHEQ 240
Cdd:PRK05707 162 CPLPSNEESLQWLQQALPESdERERIELLTLAGGSPLRALQL-HEQGVREQRARVLDGVKKLLKQqqSASQLAESWLKVP 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  241 APARLHWLATLLMDALKRHHGAAQ--VTNVDVPGLVAELANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLR 318
Cdd:PRK05707 241 LLLLFDWFCDWAHDILRYQLTQDEegLGLADMRKVLQYLAQKSPQAKVLALQDWLLEQRQKVLGKANLNRQLLLEALLVQ 320
holB TIGR00678
DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' ...
 14-201 1.01e-52

DNA polymerase III, delta' subunit; This model describes the N-terminal half of the delta' subunit of DNA polymerase III. Delta' is homologous to the gamma and tau subunits, which form an outgroup for phylogenetic comparison. The gamma/tau branch of the tree is much more tighly conserved than the delta' branch, and some members of that branch score more highly against this model than some proteins classisified as delta'. The noise cutoff is set to detect weakly scoring delta' subunits rather than to exclude gamma/tau subunits. At position 126-127 of the seed alignment, this family lacks the HM motif of gamma/tau; at 132 it has a near-invariant A vs. an invariant F in gamma/tau. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273213 [Multi-domain]  Cd Length: 188  Bit Score: 172.04  E-value: 1.01e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    14 LVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKntLGVDAV 93
Cdd:TIGR00678   4 LKRALEKGRLAHAYLFTGPEGVGKELLALALAKALLCEQRGGGEPCGECHSCRLIEAGNHPDLHRLEPEGQS--IKVDQV 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    94 REVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAPPPEQYAV 173
Cdd:TIGR00678  82 RELVEFLSRTPQESGRRVVIIEDAERMNEAAANALLKTLEEPPPNTLFILITPSPEKLLPTIRSRCQRLPFPPLSEEALL 161

                         170       180
                  ....*....|....*....|....*...
gi 16129062   174 TWLSREvTMSQDALLAALRLSAGSPGAA 201
Cdd:TIGR00678 162 QWLIRQ-GISEEAAELLLALAGGSPGRA 188
PRK06090 PRK06090
DNA polymerase III subunit delta'; Validated
 4-317 1.04e-41

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180394 [Multi-domain]  Cd Length: 319  Bit Score: 147.64  E-value: 1.04e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    4 YPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGhKSCGHCRGCQLMQAGTHPDYYTLAPEK 83
Cdd:PRK06090   5 YPWLVPVWQNWKAGLDAGRIPGALLLQSDEGLGVESLVELFSRALLCQNYQS-EACGFCHSCELMQSGNHPDLHVIKPEK 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   84 GKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHY 163
Cdd:PRK06090  84 EGKSITVEQIRQCNRLAQESSQLNGYRLFVIEPADAMNESASNALLKTLEEPAPNCLFLLVTHNQKRLLPTIVSRCQQWV 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  164 LAPPPEQYAVTWLSREVTMsqdALLAALRLSAGSPGAALALFQGDNWQARETLCQAL--AYSVPSGDwYSLLAALNHEQA 241
Cdd:PRK06090 164 VTPPSTAQAMQWLKGQGIT---VPAYALKLNMGSPLKTLAMMKEGGLEKYHKLERQLvdALSGPVSD-QLKCASLIAADP 239

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16129062  242 PARLHWLATLLMDALKRHHGAAQvtNVDVPGLVAELANHLspSRLQAILGDVCHIREQLMSVTGINRELLITDLLL 317
Cdd:PRK06090 240 LTHLSWLWLLLTDAQKVHFGVQN--EYYLPGSAALGPFTY--SGLYVSTAKLERLKEQLQQFSGLNTELLIMNWLI 311
DNApol3-delta_C pfam09115
DNA polymerase III, delta subunit, C terminal; Members of this family, which are predominantly ...
 210-319 3.40e-38

DNA polymerase III, delta subunit, C terminal; Members of this family, which are predominantly found in prokaryotic DNA polymerase III, assume an alpha helical structure, with a core of five alpha helices, and an additional small helix. They are essential for the formation of the polymerase clamp loader.


Pssm-ID: 430418 [Multi-domain]  Cd Length: 112  Bit Score: 131.60  E-value: 3.40e-38
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   210 WQARETLCQAL-AYSVPSGDWYSLLAALNHEQAPARLHWLATLLMDALKRHHGAA-QVTNVDVPGLVAELANHLSPSRLQ 287
Cdd:pfam09115   1 WQARKALLQALvALALQRGDLLSLLPLLNKDDALVRLHWLSSLLLDALKYQQGVQdQLVNQDQIALIAQLAQRLSAERLL 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 16129062   288 AILGDVCHIREQLMSVTGINRELLITDLLLRI 319
Cdd:pfam09115  81 AQLQKLLECREQLLSIPGVNRELLLTEWLLRW 112
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
14-319 7.32e-36

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 132.62  E-value: 7.32e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  14 LVASYQAGRGHHALLIQALPGMG--DDALIYAlsRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNtlGVD 91
Cdd:COG2812  22 LKNALASGRLAHAYLFTGPRGVGktTLARILA--KALNCENGPTGEPCGECESCRAIAAGSHPDVIEIDAEASNI--GVD 97

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  92 AVREVTEKLNEHARLGGAKVVwvtdaalltdaaanallKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAPPPEQY 171
Cdd:COG2812  98 DIRELIEKVSYAPVEGRYKVYiideahmltteafnallKTLEEPPPHVVFILATTEPQKLLPTILSRCQRFDFRRLPPEE 177

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062 172 AVTWLSR-----EVTMSQDALLAALRLSAGSPGAALALFQGD---NWQARETLCQALAYSVPSGDWYSLLAALNH----E 239
Cdd:COG2812 178 IAEHLAKiaereGIEIEPEALALIARAADGSMRDALSLLDQAiafGLLDRRELLLDLLEALLAGDVAALLALAEElakrG 257

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062 240 QAPAR-LHWLATLLMDALKRHHGAAQ--VTNVDVPGLVAELANHLSPSRLQAILGDVCHIREQLMSVTgiNRELLITDLL 316
Cdd:COG2812 258 RDLKRfLDDLLSLLRDLLLLKLGPDAelLVNEDERERLQELARRLSPERLLRAIQILLEARRELERNV--NPRLALEMLL 335


                ...
gi 16129062 317 LRI 319
Cdd:COG2812 336 LRL 338
DNA_pol3_delta2 pfam13177
DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required ...
 11-168 6.99e-31

DNA polymerase III, delta subunit; DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.


Pssm-ID: 433013 [Multi-domain]  Cd Length: 161  Bit Score: 114.23  E-value: 6.99e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    11 FEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKgkNTLGV 90
Cdd:pfam13177   6 IQLLQNSLENGRLSHAYLFSGPEGVGKLELALAFAKALFCEEPGDDLPCGQCRSCRRIESGNHPDLVIIEPEG--QSIKI 83

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16129062    91 DAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAPPP 168
Cdd:pfam13177  84 DQIRELQKEFSKSPYEGKKKVYIIEDAEKMTASAANSLLKFLEEPPGNTVIILLTENPSRLLPTIRSRCQIIRFKPLS 161
PRK08699 PRK08699
DNA polymerase III subunit delta'; Validated
 4-176 1.02e-29

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181538 [Multi-domain]  Cd Length: 325  Bit Score: 115.74  E-value: 1.02e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    4 YPWLRPDFEKLVASYQagRGHHALLIQALPGMGDDALIYALSRYLLCQQP-QGHKSCGHCRGCQLMQAGTHPDYYTLAP- 81
Cdd:PRK08699   3 YPWHQEQWRQIAEHWE--RRPNAWLFAGKKGIGKTAFARFAAQALLCETPaPGHKPCGECMSCHLFGQGSHPDFYEITPl 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   82 ----EKGKNTL--GVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATL 155
Cdd:PRK08699  81 sdepENGRKLLqiKIDAVREIIDNVYLTSVRGGLRVILIHPAESMNLQAANSLLKVLEEPPPQVVFLLVSHAADKVLPTI 160

                        170       180
                 ....*....|....*....|.
gi 16129062  156 RSRCRLHYLAPPPEQYAVTWL 176
Cdd:PRK08699 161 KSRCRKMVLPAPSHEEALAYL 181
PRK06964 PRK06964
DNA polymerase III subunit delta'; Validated
 4-257 1.11e-25

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235898 [Multi-domain]  Cd Length: 342  Bit Score: 104.84  E-value: 1.11e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    4 YPWLRPDFEKLvasyQAGRGH--HALLIQALPGMGDDALIYALSRYLLCQQPQ--GHkSCGHCRGCQLMQAGTHPDYYTL 79
Cdd:PRK06964   3 YPWQTDDWNRL----QALRARlpHALLLHGQAGIGKLDFAQHLAQGLLCETPQpdGE-PCGTCAACNWFAQGNHPDYRIV 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   80 APE--------------------KGKNT------LGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLE 133
Cdd:PRK06964  78 RPEalaaeapgaadeakeadadeGGKKTkapskeIKIEQVRALLDFCGVGTHRGGARVVVLYPAEALNVAAANALLKTLE 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  134 EPPAETWFFLATREPERLLATLRSRCRLHYLAPPPEQYAVTWLSREvtmSQDALLAALRLSAGSPGAALALFQGDNWQAR 213
Cdd:PRK06964 158 EPPPGTVFLLVSARIDRLLPTILSRCRQFPMTVPAPEAAAAWLAAQ---GVADADALLAEAGGAPLAALALASDENRPLR 234

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 16129062  214 ETLCQALAysvpSGDWYSLLAALNHEQ---APARLHWLATLLMDALK 257
Cdd:PRK06964 235 DWTLGQLA----AGAACDAFACAETLQklpVPAVLGWLQRWLYDLLA 277
PRK08769 PRK08769
DNA polymerase III subunit delta'; Validated
 5-255 3.58e-22

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181551 [Multi-domain]  Cd Length: 319  Bit Score: 95.03  E-value: 3.58e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    5 PWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQghkSCGHCRGCQLMQAGTHPDYYTLA---- 80
Cdd:PRK08769   7 PWQQRAYDQTVAALDAGRLGHGLLICGPEGLGKRAVALALAEHVLASGPD---PAAAQRTRQLIAAGTHPDLQLVSfipn 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   81 --PEKGKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSR 158
Cdd:PRK08769  84 rtGDKLRTEIVIEQVREISQKLALTPQYGIAQVVIVDPADAINRAACNALLKTLEEPSPGRYLWLISAQPARLPATIRSR 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  159 C-RLHYLAPPPEQyAVTWLSREvTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQALAySVPSGDWYSLLAA-- 235
Cdd:PRK08769 164 CqRLEFKLPPAHE-ALAWLLAQ-GVSERAAQEALDAARGHPGLAAQWLREDGLALRRAVAQDLE-QIASGRAGAVDVAqr 240

                        250       260
                 ....*....|....*....|..
gi 16129062  236 -LNHEQAPARLHWLATL-LMDA 255
Cdd:PRK08769 241 wTNDGQADQRLRHAADLaLAQA 262
PRK07471 PRK07471
DNA polymerase III subunit delta'; Validated
 14-264 2.07e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236022 [Multi-domain]  Cd Length: 365  Bit Score: 84.70  E-value: 2.07e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   14 LVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCG-----------HcRGCQLMQAGTHPDYYTL--- 79
Cdd:PRK07471  31 LLDAYRSGRLHHAWLIGGPQGIGKATLAYRMARFLLATPPPGGDGAVppptslaidpdH-PVARRIAAGAHGGLLTLers 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   80 APEKG---KNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLR 156
Cdd:PRK07471 110 WNEKGkrlRTVITVDEVRELISFFGLTAAEGGWRVVIVDTADEMNANAANALLKVLEEPPARSLFLLVSHAPARLLPTIR 189

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  157 SRCR---LHYLAPPPEQYAVTWLSREVtmSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQALAySVPSGDwysll 233
Cdd:PRK07471 190 SRCRklrLRPLAPEDVIDALAAAGPDL--PDDPRAALAALAEGSVGRALRLAGGDGLALYRRLTALLD-TLPRLD----- 261

                        250       260       270
                 ....*....|....*....|....*....|.
gi 16129062  234 aalnheqaPARLHWLAtllmDALKRHHGAAQ 264
Cdd:PRK07471 262 --------RRALHALA----DAAAGRDRAAR 280
PRK07940 PRK07940
DNA polymerase III subunit delta'; Validated
 25-178 5.71e-18

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236134 [Multi-domain]  Cd Length: 394  Bit Score: 83.81  E-value: 5.71e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   25 HALLIQALPGMGDDALIYALSRYLLCQQPQGHkSCGHCRGCQLMQAGTHPDYYTLAPEKgkNTLGVDAVREVTEKLNEHA 104
Cdd:PRK07940  37 HAWLFTGPPGSGRSVAARAFAAALQCTDPDEP-GCGECRACRTVLAGTHPDVRVVAPEG--LSIGVDEVRELVTIAARRP 113

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16129062  105 RLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAPPPEQYAVTWLSR 178
Cdd:PRK07940 114 STGRWRIVVIEDADRLTERAANALLKAVEEPPPRTVWLLCAPSPEDVLPTIRSRCRHVALRTPSVEAVAEVLVR 187
PRK14963 PRK14963
DNA polymerase III subunits gamma and tau; Provisional
 12-163 1.01e-16

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184927 [Multi-domain]  Cd Length: 504  Bit Score: 80.65  E-value: 1.01e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   12 EKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQgHKSCGHCRGCQLMQAGTHPDyyTLAPEKGKNTlGVD 91
Cdd:PRK14963  24 EVLLAALRQGRLGHAYLFSGPRGVGKTTTARLIAMAVNCSGED-PKPCGECESCLAVRRGAHPD--VLEIDAASNN-SVE 99

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129062   92 AVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRlHY 163
Cdd:PRK14963 100 DVRDLREKVLLAPLRGGRKVYILDEAHMMSKSAFNALLKTLEEPPEHVIFILATTEPEKMPPTILSRTQ-HF 170
PRK08691 PRK08691
DNA polymerase III subunits gamma and tau; Validated
 21-159 1.59e-16

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236333 [Multi-domain]  Cd Length: 709  Bit Score: 80.52  E-value: 1.59e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   21 GRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYytLAPEKGKNTlGVDAVREVTEKL 100
Cdd:PRK08691  35 GRLHHAYLLTGTRGVGKTTIARILAKSLNCENAQHGEPCGVCQSCTQIDAGRYVDL--LEIDAASNT-GIDNIREVLENA 111

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 16129062  101 NEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK08691 112 QYAPTAGKYKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPHKVPVTVLSRC 170
PRK14953 PRK14953
DNA polymerase III subunits gamma and tau; Provisional
 21-178 2.25e-16

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237867 [Multi-domain]  Cd Length: 486  Bit Score: 79.48  E-value: 2.25e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   21 GRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKntlGVDAVREVTEKL 100
Cdd:PRK14953  35 QRVSHAYIFAGPRGTGKTTIARILAKVLNCLNPQEGEPCGKCENCVEIDKGSFPDLIEIDAASNR---GIDDIRALRDAV 111

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16129062  101 NEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAPPPEQYAVTWLSR 178
Cdd:PRK14953 112 SYTPIKGKYKVYIIDEAHMLTKEAFNALLKTLEEPPPRTIFILCTTEYDKIPPTILSRCQRFIFSKPTKEQIKEYLKR 189
PRK14962 PRK14962
DNA polymerase III subunits gamma and tau; Provisional
 14-161 3.21e-15

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237869 [Multi-domain]  Cd Length: 472  Bit Score: 75.96  E-value: 3.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   14 LVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKntlGVDAV 93
Cdd:PRK14962  26 IINALKKNSISHAYIFAGPRGTGKTTVARILAKSLNCENRKGVEPCNECRACRSIDEGTFMDVIELDAASNR---GIDEI 102

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16129062   94 REVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRL 161
Cdd:PRK14962 103 RKIRDAVGYRPMEGKYKVYIIDEVHMLTKEAFNALLKTLEEPPSHVVFVLATTNLEKVPPTIISRCQV 170
PRK08058 PRK08058
DNA polymerase III subunit delta'; Validated
 14-321 1.28e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 181214 [Multi-domain]  Cd Length: 329  Bit Score: 73.42  E-value: 1.28e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   14 LVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEkGKnTLGVDAV 93
Cdd:PRK08058  18 LQNSIAKNRLSHAYLFEGAKGTGKKATALWLAKSLFCLERNGVEPCGTCTNCKRIDSGNHPDVHLVAPD-GQ-SIKKDQI 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   94 REVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR-LHYLAPPPEQYA 172
Cdd:PRK08058  96 RYLKEEFSKSGVESNKKVYIIEHADKMTASAANSLLKFLEEPSGGTTAILLTENKHQILPTILSRCQvVEFRPLPPESLI 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  173 VTWLSREVTMSQdalLAALRLSAGSPGAALALFQgDNW--QARET---LCQALAysvpSGDWYSLLA--------ALNHE 239
Cdd:PRK08058 176 QRLQEEGISESL---ATLLAGLTNSVEEALALSE-DDWfaQARALvikLYEALH----EKDLQSFVFvqekwmplFKEKD 247

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  240 QAPARLHWLATLLMDALKRHHGAAQ-VTNVDVPGLVAELANHLSPSRLQAILGDVCHIREQLMSvtGINRELLITDLLLR 318
Cdd:PRK08058 248 QQQLGLDLLLLIYRDLLYLQLGEEDrLVFREQKEMLQQLALSYSQQQIVAALELILEAKRRLNS--NVNFQLVMEQLVLR 325


                 ...
gi 16129062  319 IEH 321
Cdd:PRK08058 326 LQE 328
PRK09112 PRK09112
DNA polymerase III subunit delta'; Validated
 14-225 2.40e-14

DNA polymerase III subunit delta'; Validated


Pssm-ID: 169667 [Multi-domain]  Cd Length: 351  Bit Score: 72.76  E-value: 2.40e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   14 LVASYQAGRGHHALLIQALPGMGDDALIYALSRYLL-----CQQPQGHKSCGHCR--GCQLMQaGTHPDYYTLA------ 80
Cdd:PRK09112  35 LAQAYREGKLHHALLFEGPEGIGKATLAFHLANHILshpdpAEAPETLADPDPASpvWRQIAQ-GAHPNLLHITrpfdek 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   81 PEKGKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRC- 159
Cdd:PRK09112 114 TGKFKTAITVDEIRRVGHFLSQTSGDGNWRIVIIDPADDMNRNAANAILKTLEEPPARALFILISHSSGRLLPTIRSRCq 193

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16129062  160 --RLHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQALAYSVP 225
Cdd:PRK09112 194 piSLKPLDDDELKKALSHLGSSQGSDGEITEALLQRSKGSVRKALLLLNYGGLEIIATIDQLLAGSGP 261
PRK07276 PRK07276
DNA polymerase III subunit delta'; Validated
 11-179 1.20e-12

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180916 [Multi-domain]  Cd Length: 290  Bit Score: 67.35  E-value: 1.20e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   11 FEKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYllCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKgkNTLGV 90
Cdd:PRK07276  11 FQRFQTILEQDRLNHAYLFSGDFASFEMALFLAQSLF--CEQKEGVLPCGHCRSCRLIEQGEFSDVTVIEPQG--QVIKT 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   91 DAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLaPPPEQ 170
Cdd:PRK07276  87 DTIRELVKNFSQSGYEGKQQVFIIKDADKMHVNAANSLLKVIEEPQSEIYIFLLTNDENKVLPTIKSRTQIFHF-PKNEA 165


                 ....*....
gi 16129062  171 YAVTWLSRE 179
Cdd:PRK07276 166 YLIQLLEQK 174
PRK14969 PRK14969
DNA polymerase III subunits gamma and tau; Provisional
 6-159 2.28e-12

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237873 [Multi-domain]  Cd Length: 527  Bit Score: 67.47  E-value: 2.28e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    6 WlRP-DFEKLVA----------SYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHP 74
Cdd:PRK14969  10 W-RPkSFSELVGqehvvraltnALEQQRLHHAYLFTGTRGVGKTTLARILAKSLNCETGVTATPCGVCSACLEIDSGRFV 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   75 DYYTLapEKGKNTlGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLAT 154
Cdd:PRK14969  89 DLIEV--DAASNT-QVDAMRELLDNAQYAPTRGRFKVYIIDEVHMLSKSAFNAMLKTLEEPPEHVKFILATTDPQKIPVT 165


                 ....*
gi 16129062  155 LRSRC 159
Cdd:PRK14969 166 VLSRC 170
PRK06305 PRK06305
DNA polymerase III subunits gamma and tau; Validated
 22-185 4.07e-12

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180523 [Multi-domain]  Cd Length: 451  Bit Score: 66.72  E-value: 4.07e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   22 RGHHALLIQALPGMGDDALIYALSRYLLCQQP-QGHKSCGHCRGCQLMQAGTHPDYYTLapeKGKNTLGVDAVREVTEKL 100
Cdd:PRK06305  37 RAAHAYLFSGIRGTGKTTLARIFAKALNCQNPtEDQEPCNQCASCKEISSGTSLDVLEI---DGASHRGIEDIRQINETV 113

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  101 NEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAPPPEQYAVTWLSrev 180
Cdd:PRK06305 114 LFTPSKSRYKIYIIDEVHMLTKEAFNSLLKTLEEPPQHVKFFLATTEIHKIPGTILSRCQKMHLKRIPEETIIDKLA--- 190


                 ....*
gi 16129062  181 TMSQD 185
Cdd:PRK06305 191 LIAKQ 195
PRK14956 PRK14956
DNA polymerase III subunits gamma and tau; Provisional
 17-160 1.61e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184920 [Multi-domain]  Cd Length: 484  Bit Score: 64.97  E-value: 1.61e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   17 SYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLapEKGKNTlGVDAVREV 96
Cdd:PRK14956  33 ALKSGKIGHAYIFFGPRGVGKTTIARILAKRLNCENPIGNEPCNECTSCLEITKGISSDVLEI--DAASNR-GIENIREL 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16129062   97 TEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK14956 110 RDNVKFAPMGGKYKVYIIDEVHMLTDQSFNALLKTLEEPPAHIVFILATTEFHKIPETILSRCQ 173
dnaX_nterm TIGR02397
DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ ...
 21-159 2.01e-11

DNA polymerase III, subunit gamma and tau; This model represents the well-conserved first ~ 365 amino acids of the translation of the dnaX gene. The full-length product of the dnaX gene in the model bacterium E. coli is the DNA polymerase III tau subunit. A translational frameshift leads to early termination and a truncated protein subunit gamma, about 1/3 shorter than tau and present in roughly equal amounts. This frameshift mechanism is not necessarily universal for species with DNA polymerase III but appears conserved in the exterme thermophile Thermus thermophilis. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274111 [Multi-domain]  Cd Length: 355  Bit Score: 64.13  E-value: 2.01e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    21 GRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPekGKNTlGVDAVREVTEKL 100
Cdd:TIGR02397  33 GRIAHAYLFSGPRGTGKTSIARIFAKALNCQNGPDGEPCNECESCKEINSGSSLDVIEIDA--ASNN-GVDDIREILDNV 109

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16129062   101 NEHARLGGAKV------------VWvtdaalltdaaaNALLKTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:TIGR02397 110 KYAPSSGKYKVyiidevhmlsksAF------------NALLKTLEEPPEHVVFILATTEPHKIPATILSRC 168
PRK14958 PRK14958
DNA polymerase III subunits gamma and tau; Provisional
 24-172 6.35e-11

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184922 [Multi-domain]  Cd Length: 509  Bit Score: 63.21  E-value: 6.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   24 HHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTL-APEKGKntlgVDAVREVTEKLNE 102
Cdd:PRK14958  38 HHAYLFTGTRGVGKTTISRILAKCLNCEKGVSANPCNDCENCREIDEGRFPDLFEVdAASRTK----VEDTRELLDNIPY 113

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16129062  103 HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRC-RLHYLAPPPEQYA 172
Cdd:PRK14958 114 APTKGRFKVYLIDEVHMLSGHSFNALLKTLEEPPSHVKFILATTDHHKLPVTVLSRClQFHLAQLPPLQIA 184
PRK12323 PRK12323
DNA polymerase III subunit gamma/tau;
8-159 4.83e-10

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237057 [Multi-domain]  Cd Length: 700  Bit Score: 60.66  E-value: 4.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    8 RP-DFEKLVA----------SYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGH-----KSCGHCRGCQLMQAG 71
Cdd:PRK12323  11 RPrDFTTLVGqehvvralthALEQQRLHHAYLFTGTRGVGKTTLSRILAKSLNCTGADGEggitaQPCGQCRACTEIDAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   72 THPDYYTLAPEKGKntlGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERL 151
Cdd:PRK12323  91 RFVDYIEMDAASNR---GVDEMAQLLDKAVYAPTAGRFKVYMIDEVHMLTNHAFNAMLKTLEEPPEHVKFILATTDPQKI 167


                 ....*...
gi 16129062  152 LATLRSRC 159
Cdd:PRK12323 168 PVTVLSRC 175
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 19-160 5.83e-10

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 60.46  E-value: 5.83e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   19 QAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLapeKGKNTLGVDAVREVTE 98
Cdd:PRK14959  33 QENRVAPAYLFSGTRGVGKTTIARIFAKALNCETAPTGEPCNTCEQCRKVTQGMHVDVVEI---DGASNRGIDDAKRLKE 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129062   99 KLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK14959 110 AIGYAPMEGRYKVFIIDEAHMLTREAFNALLKTLEEPPARVTFVLATTEPHKFPVTIVSRCQ 171
PRK14960 PRK14960
DNA polymerase III subunit gamma/tau;
14-166 1.48e-09

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237868 [Multi-domain]  Cd Length: 702  Bit Score: 59.29  E-value: 1.48e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   14 LVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTL-APEKGKntlgVDA 92
Cdd:PRK14960  27 LSSALERGRLHHAYLFTGTRGVGKTTIARILAKCLNCETGVTSTPCEVCATCKAVNEGRFIDLIEIdAASRTK----VED 102

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16129062   93 VREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAP 166
Cdd:PRK14960 103 TRELLDNVPYAPTQGRFKVYLIDEVHMLSTHSFNALLKTLEEPPEHVKFLFATTDPQKLPITVISRCLQFTLRP 176
PRK14950 PRK14950
DNA polymerase III subunits gamma and tau; Provisional
 19-160 2.76e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237864 [Multi-domain]  Cd Length: 585  Bit Score: 58.28  E-value: 2.76e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   19 QAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGH-KSCGHCRGCQLMQAGTHPDYYTLapEKGKNTlGVDAVREVT 97
Cdd:PRK14950  33 AEGRVAHAYLFTGPRGVGKTSTARILAKAVNCTTNDPKgRPCGTCEMCRAIAEGSAVDVIEM--DAASHT-SVDDAREII 109

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16129062   98 EKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK14950 110 ERVQFRPALARYKVYIIDEVHMLSTAAFNALLKTLEEPPPHAIFILATTEVHKVPATILSRCQ 172
PRK14961 PRK14961
DNA polymerase III subunits gamma and tau; Provisional
 17-177 3.41e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184925 [Multi-domain]  Cd Length: 363  Bit Score: 57.51  E-value: 3.41e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   17 SYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTL-APEKGKntlgVDAVRE 95
Cdd:PRK14961  31 GLSLGRIHHAWLLSGTRGVGKTTIARLLAKSLNCQNGITSNPCRKCIICKEIEKGLCLDLIEIdAASRTK----VEEMRE 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   96 VTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAPPPEQYAVTW 175
Cdd:PRK14961 107 ILDNIYYSPSKSRFKVYLIDEVHMLSRHSFNALLKTLEEPPQHIKFILATTDVEKIPKTILSRCLQFKLKIISEEKIFNF 186


                 ..
gi 16129062  176 LS 177
Cdd:PRK14961 187 LK 188
PRK14965 PRK14965
DNA polymerase III subunits gamma and tau; Provisional
 21-159 4.53e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237871 [Multi-domain]  Cd Length: 576  Bit Score: 57.44  E-value: 4.53e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   21 GRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLapEKGKNTlGVDAVREVTEK- 99
Cdd:PRK14965  35 GRVAHAFLFTGARGVGKTSTARILAKALNCEQGLTAEPCNVCPPCVEITEGRSVDVFEI--DGASNT-GVDDIRELRENv 111

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129062  100 --LNEHARLggaKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK14965 112 kyLPSRSRY---KIFIIDEVHMLSTNAFNALLKTLEEPPPHVKFIFATTEPHKVPITILSRC 170
PRK14951 PRK14951
DNA polymerase III subunits gamma and tau; Provisional
 22-169 7.27e-09

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237865 [Multi-domain]  Cd Length: 618  Bit Score: 57.03  E-value: 7.27e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   22 RGHHALLIQALPGMGDDALIYALSRYLLCQQPQGH-----KSCGHCRGCQLMQAGTHPDYYTLAPEKGKntlGVDAVREV 96
Cdd:PRK14951  36 RLHHAYLFTGTRGVGKTTVSRILAKSLNCQGPDGQggitaTPCGVCQACRDIDSGRFVDYTELDAASNR---GVDEVQQL 112

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16129062   97 TEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLHYLAP-PPE 169
Cdd:PRK14951 113 LEQAVYKPVQGRFKVFMIDEVHMLTNTAFNAMLKTLEEPPEYLKFVLATTDPQKVPVTVLSRCLQFNLRPmAPE 186
PRK06647 PRK06647
DNA polymerase III subunits gamma and tau; Validated
 10-160 7.59e-09

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235845 [Multi-domain]  Cd Length: 563  Bit Score: 56.70  E-value: 7.59e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   10 DF--EKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLapeKGKNT 87
Cdd:PRK06647  22 DFvvETLKHSIESNKIANAYIFSGPRGVGKTSSARAFARCLNCVNGPTPMPCGECSSCKSIDNDNSLDVIEI---DGASN 98

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16129062   88 LGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK06647  99 TSVQDVRQIKEEIMFPPASSRYRVYIIDEVHMLSNSAFNALLKTIEEPPPYIVFIFATTEVHKLPATIKSRCQ 171
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
6-178 2.20e-08

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 55.63  E-value: 2.20e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    6 WLRPDFEKLVA----------SYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPD 75
Cdd:PRK07003  10 WRPKDFASLVGqehvvralthALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACREIDEGRFVD 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   76 YYTL--APEKGKNTLGVDAVREVTEKLNehARLggaKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLA 153
Cdd:PRK07003  90 YVEMdaASNRGVDEMAALLERAVYAPVD--ARF---KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPV 164

                        170       180
                 ....*....|....*....|....*
gi 16129062  154 TLRSRCRLHYLAPPPEQYAVTWLSR 178
Cdd:PRK07003 165 TVLSRCLQFNLKQMPAGHIVSHLER 189
PRK14957 PRK14957
DNA polymerase III subunits gamma and tau; Provisional
 14-162 2.30e-08

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184921 [Multi-domain]  Cd Length: 546  Bit Score: 55.47  E-value: 2.30e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   14 LVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDyytLAPEKGKNTLGVDAV 93
Cdd:PRK14957  28 LVHALETQKVHHAYLFTGTRGVGKTTLGRLLAKCLNCKTGVTAEPCNKCENCVAINNNSFID---LIEIDAASRTGVEET 104

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   94 REVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRC-RLH 162
Cdd:PRK14957 105 KEILDNIQYMPSQGRYKVYLIDEVHMLSKQSFNALLKTLEEPPEYVKFILATTDYHKIPVTILSRCiQLH 174
PRK14955 PRK14955
DNA polymerase III subunits gamma and tau; Provisional
 17-160 1.01e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184919 [Multi-domain]  Cd Length: 397  Bit Score: 52.97  E-value: 1.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   17 SYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQ--------PQGHKSCGHCRGCQLMQAGTHpdyYTLAPEKGKNTL 88
Cdd:PRK14955  31 SLRMGRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRmiddadylQEVTEPCGECESCRDFDAGTS---LNISEFDAASNN 107

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129062   89 GVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK14955 108 SVDDIRLLRENVRYGPQKGRYRVYIIDEVHMLSIAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQ 179
PRK05564 PRK05564
DNA polymerase III subunit delta'; Validated
 83-166 2.99e-07

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180132 [Multi-domain]  Cd Length: 313  Bit Score: 51.19  E-value: 2.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   83 KGKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRLH 162
Cdd:PRK05564  68 INKKSIGVDDIRNIIEEVNKKPYEGDKKVIIIYNSEKMTEQAQNAFLKTIEEPPKGVFIILLCENLEQILDTIKSRCQIY 147


                 ....
gi 16129062  163 YLAP 166
Cdd:PRK05564 148 KLNR 151
PRK14952 PRK14952
DNA polymerase III subunits gamma/tau;
12-167 3.88e-07

DNA polymerase III subunits gamma/tau;


Pssm-ID: 237866 [Multi-domain]  Cd Length: 584  Bit Score: 51.42  E-value: 3.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   12 EKLVASYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLM--QAGTHPDYYTL-APEKGkntl 88
Cdd:PRK14952  23 EPLSSALDAGRINHAYLFSGPRGCGKTSSARILARSLNCAQGPTATPCGVCESCVALapNGPGSIDVVELdAASHG---- 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   89 GVDAVREvtekLNEHARLGGA----KVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRlHY- 163
Cdd:PRK14952  99 GVDDTRE----LRDRAFYAPAqsryRIFIVDEAHMVTTAGFNALLKIVEEPPEHLIFIFATTEPEKVLPTIRSRTH-HYp 173


                 ....*.
gi 16129062  164 --LAPP 167
Cdd:PRK14952 174 frLLPP 179
PRK08451 PRK08451
DNA polymerase III subunits gamma and tau; Validated
 20-158 4.11e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236267 [Multi-domain]  Cd Length: 535  Bit Score: 51.57  E-value: 4.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   20 AGRGHHALLIQALPGMG--DDALIYAlsRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLapeKGKNTLGVDAVREVT 97
Cdd:PRK08451  32 NNRLAHAYLFSGLRGSGktSSARIFA--RALVCEQGPSSTPCDTCIQCQSALENRHIDIIEM---DAASNRGIDDIRELI 106

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16129062   98 EKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSR 158
Cdd:PRK08451 107 EQTKYKPSMARFKIFIIDEVHMLTKEAFNALLKTLEEPPSYVKFILATTDPLKLPATILSR 167
PRK05896 PRK05896
DNA polymerase III subunits gamma and tau; Validated
 25-160 4.99e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235638 [Multi-domain]  Cd Length: 605  Bit Score: 51.38  E-value: 4.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   25 HALLIQALPGMGDDALIYALSRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLapEKGKNTlGVDAVREVTEKLNEHA 104
Cdd:PRK05896  39 HAYIFSGPRGIGKTSIAKIFAKAINCLNPKDGDCCNSCSVCESINTNQSVDIVEL--DAASNN-GVDEIRNIIDNINYLP 115

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 16129062  105 RLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK05896 116 TTFKYKVYIIDEAHMLSTSAWNALLKTLEEPPKHVVFIFATTEFQKIPLTIISRCQ 171
PRK14948 PRK14948
DNA polymerase III subunit gamma/tau;
130-159 7.71e-07

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237862 [Multi-domain]  Cd Length: 620  Bit Score: 50.73  E-value: 7.71e-07
                         10        20        30
                 ....*....|....*....|....*....|
gi 16129062  130 KTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK14948 143 KTLEEPPPRVVFVLATTDPQRVLPTIISRC 172
PRK14954 PRK14954
DNA polymerase III subunits gamma and tau; Provisional
 17-160 8.83e-07

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184918 [Multi-domain]  Cd Length: 620  Bit Score: 50.33  E-value: 8.83e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   17 SYQAGRGHHALLIQALPGMGDDALIYALSRYLLCQQ----PQGHKS----CGHCRGCQLMQAGTHpdyYTLAPEKGKNTL 88
Cdd:PRK14954  31 SLRMDRVGHGYIFSGLRGVGKTTAARVFAKAVNCQRmiddPVYLQEvtepCGECESCRDFDAGTS---LNISEFDAASNN 107

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 16129062   89 GVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR 160
Cdd:PRK14954 108 SVDDIRQLRENVRYGPQKGRYRVYIIDEVHMLSTAAFNAFLKTLEEPPPHAIFIFATTELHKIPATIASRCQ 179
PRK06645 PRK06645
DNA polymerase III subunits gamma and tau; Validated
 57-160 3.68e-06

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 180643 [Multi-domain]  Cd Length: 507  Bit Score: 48.32  E-value: 3.68e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   57 KSCGHCRGCQLMQAGTHPDYYTLapeKGKNTLGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPP 136
Cdd:PRK06645  80 KTCEQCTNCISFNNHNHPDIIEI---DAASKTSVDDIRRIIESAEYKPLQGKHKIFIIDEVHMLSKGAFNALLKTLEEPP 156

                         90       100
                 ....*....|....*....|....
gi 16129062  137 AETWFFLATREPERLLATLRSRCR 160
Cdd:PRK06645 157 PHIIFIFATTEVQKIPATIISRCQ 180
PRK14970 PRK14970
DNA polymerase III subunits gamma and tau; Provisional
 89-161 1.36e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184934 [Multi-domain]  Cd Length: 367  Bit Score: 46.41  E-value: 1.36e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16129062   89 GVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRL 161
Cdd:PRK14970  89 SVDDIRNLIDQVRIPPQTGKYKIYIIDEVHMLSSAAFNAFLKTLEEPPAHAIFILATTEKHKIIPTILSRCQI 161
PRK05563 PRK05563
DNA polymerase III subunits gamma and tau; Validated
 130-159 1.49e-05

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235505 [Multi-domain]  Cd Length: 559  Bit Score: 46.40  E-value: 1.49e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 16129062  130 KTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK05563 141 KTLEEPPAHVIFILATTEPHKIPATILSRC 170
PRK14949 PRK14949
DNA polymerase III subunits gamma and tau; Provisional
 130-159 5.33e-05

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237863 [Multi-domain]  Cd Length: 944  Bit Score: 45.10  E-value: 5.33e-05
                         10        20        30
                 ....*....|....*....|....*....|
gi 16129062  130 KTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK14949 141 KTLEEPPEHVKFLLATTDPQKLPVTVLSRC 170
PRK06581 PRK06581
DNA polymerase III subunit delta'; Validated
 74-159 6.05e-05

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235833 [Multi-domain]  Cd Length: 263  Bit Score: 44.07  E-value: 6.05e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   74 PDYYTLAPEKGKNT----LGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPE 149
Cdd:PRK06581  51 PDYHFIARETSATSnaknISIEQIRKLQDFLSKTSAISGYKVAIIYSAELMNLNAANSCLKILEDAPKNSYIFLITSRAA 130

                         90
                 ....*....|
gi 16129062  150 RLLATLRSRC 159
Cdd:PRK06581 131 SIISTIRSRC 140
PRK14971 PRK14971
DNA polymerase III subunit gamma/tau;
25-161 7.11e-05

DNA polymerase III subunit gamma/tau;


Pssm-ID: 237874 [Multi-domain]  Cd Length: 614  Bit Score: 44.38  E-value: 7.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   25 HALLIQALPGMGDDALIYALSRYLLCQQPQGH-KSCGHCRGCQLMQAGTHPDYYTLapEKGKNTlGVDAVREVTEKLNEH 103
Cdd:PRK14971  40 HAYLFCGPRGVGKTTCARIFAKTINCQNLTADgEACNECESCVAFNEQRSYNIHEL--DAASNN-SVDDIRNLIEQVRIP 116

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 16129062  104 ARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCRL 161
Cdd:PRK14971 117 PQIGKYKIYIIDEVHMLSQAAFNAFLKTLEEPPSYAIFILATTEKHKILPTILSRCQI 174
PRK07132 PRK07132
DNA polymerase III subunit delta'; Validated
 130-159 4.08e-04

DNA polymerase III subunit delta'; Validated


Pssm-ID: 180855 [Multi-domain]  Cd Length: 299  Bit Score: 41.63  E-value: 4.08e-04
                         10        20        30
                 ....*....|....*....|....*....|
gi 16129062  130 KTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK07132 112 KTIEEPPKDTYFLLTTKNINKVLPTIVSRC 141
PRK05917 PRK05917
DNA polymerase III subunit delta'; Validated
 5-159 4.20e-04

DNA polymerase III subunit delta'; Validated


Pssm-ID: 102059 [Multi-domain]  Cd Length: 290  Bit Score: 41.32  E-value: 4.20e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062    5 PWlrpdfEKLVASYQAGRGHHALLI--QALPGMGDDALIYAlSRYLLCQQPQG-HKscghcrgcqlMQAGTHPDYYTLAP 81
Cdd:PRK05917   5 AW-----EALIQRVRDQKVPSAIILhgQDLSNLSARAYELA-SLILKETSPEAaYK----------ISQKIHPDIHEFSP 68

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 16129062   82 EkGKNTL-GVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK05917  69 Q-GKGRLhSIETPRAIKKQIWIHPYESPYKIYIIHEADRMTLDAISAFLKVLEDPPQHGVIILTSAKPQRLPPTIRSRS 146
PRK07399 PRK07399
DNA polymerase III subunit delta'; Validated
 130-212 5.08e-04

DNA polymerase III subunit delta'; Validated


Pssm-ID: 236011 [Multi-domain]  Cd Length: 314  Bit Score: 41.42  E-value: 5.08e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062  130 KTLEEPPAETwFFLATREPERLLATLRSRCRLHYLAPPPEQYAVTWLSR--EVTMSQDALLAALRLSAGSPGAALALFQg 207
Cdd:PRK07399 146 KTLEEPGNGT-LILIAPSPESLLPTIVSRCQIIPFYRLSDEQLEQVLKRlgDEEILNINFPELLALAQGSPGAAIANIE- 223


                 ....*
gi 16129062  208 dNWQA 212
Cdd:PRK07399 224 -QLQS 227
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 130-168 9.33e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 41.12  E-value: 9.33e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|..
gi 16129062  130 KTLEEPPAETWFFLATREPERLLATLRSRCRlHY---LAPPP 168
Cdd:PRK07764 142 KIVEEPPEHLKFIFATTEPDKVIGTIRSRTH-HYpfrLVPPE 182
PRK07994 PRK07994
DNA polymerase III subunits gamma and tau; Validated
 130-159 1.27e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236138 [Multi-domain]  Cd Length: 647  Bit Score: 40.62  E-value: 1.27e-03
                         10        20        30
                 ....*....|....*....|....*....|
gi 16129062  130 KTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK07994 141 KTLEEPPEHVKFLLATTDPQKLPVTILSRC 170
PRK14964 PRK14964
DNA polymerase III subunits gamma and tau; Provisional
 59-159 1.98e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 237870 [Multi-domain]  Cd Length: 491  Bit Score: 39.77  E-value: 1.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   59 CGHCRGCQLMQAGTHPDYYTLapEKGKNTlGVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAE 138
Cdd:PRK14964  70 CGTCHNCISIKNSNHPDVIEI--DAASNT-SVDDIKVILENSCYLPISSKFKVYIIDEVHMLSNSAFNALLKTLEEPAPH 146

                         90       100
                 ....*....|....*....|.
gi 16129062  139 TWFFLATREPERLLATLRSRC 159
Cdd:PRK14964 147 VKFILATTEVKKIPVTIISRC 167
PRK05818 PRK05818
DNA polymerase III subunit delta'; Validated
 25-159 6.78e-03

DNA polymerase III subunit delta'; Validated


Pssm-ID: 235618 [Multi-domain]  Cd Length: 261  Bit Score: 37.50  E-value: 6.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   25 HALLIQALPGMGDDALIYALSRYLLCQQPQGhkSCGHCRGCQLMQAGTHPDYYTLAPEKgkNTLGVDAVREVTEKLN-EH 103
Cdd:PRK05818   8 HPLLLIERKGSFLKPFLYEYLTSIVCTKANG--FCKTCESCLKILNGKYNDFYLIFDQK--NPIKKEDALSIINKLNrPS 83

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 16129062  104 ARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRC 159
Cdd:PRK05818  84 VESNGKKIYIIYGIEKLNKQSANSLLKLIEEPPKNTYGIFTTRNENNILNTILSRC 139
PRK07133 PRK07133
DNA polymerase III subunits gamma and tau; Validated
 89-158 7.01e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 235943 [Multi-domain]  Cd Length: 725  Bit Score: 38.26  E-value: 7.01e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16129062   89 GVDAVREVTEKLNEHARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSR 158
Cdd:PRK07133  99 GVDEIRELIENVKNLPTQSKYKIYIIDEVHMLSKSAFNALLKTLEEPPKHVIFILATTEVHKIPLTILSR 168
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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