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Conserved domains on  [gi|16131211|ref|NP_417791|]
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Type II secretion system protein GspK [Escherichia coli str. K-12 substr. MG1655]

Protein Classification

general secretion pathway protein GspK( domain architecture ID 12048600)

general secretion pathway protein GspK is involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
T2SSK pfam03934
Type II secretion system (T2SS), protein K; Members of this family are involved in the Type II ...
31-314 5.77e-80

Type II secretion system (T2SS), protein K; Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.


:

Pssm-ID: 427597 [Multi-domain]  Cd Length: 283  Bit Score: 244.93  E-value: 5.77e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211    31 FHSQLQRTRQVNHHLQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQHCFNLNALA 110
Cdd:pfam03934   2 QQLQVRRTENLQARQQAYWYALGAEALARQILRDDLRDSPGVDHLDQPWAQPLQPFPLDGGEVSGRIEDLQGCFNLNALV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211   111 kiSDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSP-RFHGAEDSFYQSQTPPRHSANQMLFLTGELR 189
Cdd:pfam03934  82 --ADGAPPKDPAALQQFQRLLEALGLDAAQAERLADALADWLDADDDPpSPGGAEDSYYLSLSPPYLPANQPLADVSELR 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211   190 QIKGITENIYQRLIPYVCVLPTTELSINLNMLtenDIPLFRALFLnNITDADARVLLQKRPREGWLTTDAFlyWAQQDFS 269
Cdd:pfam03934 160 LVLGFTPELYARLRPYVCALPGDRTPINVNTA---PAEVLAALFD-GLSLDQAQALLAQRPADGFESVDDF--LAQPALG 233
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 16131211   270 GV-KPLVAQVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQ 314
Cdd:pfam03934 234 GGiAPSTAQLKTLLTVKSSYFLLESRVRVDDARVRLRSLLHRDGGG 279
 
Name Accession Description Interval E-value
T2SSK pfam03934
Type II secretion system (T2SS), protein K; Members of this family are involved in the Type II ...
31-314 5.77e-80

Type II secretion system (T2SS), protein K; Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.


Pssm-ID: 427597 [Multi-domain]  Cd Length: 283  Bit Score: 244.93  E-value: 5.77e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211    31 FHSQLQRTRQVNHHLQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQHCFNLNALA 110
Cdd:pfam03934   2 QQLQVRRTENLQARQQAYWYALGAEALARQILRDDLRDSPGVDHLDQPWAQPLQPFPLDGGEVSGRIEDLQGCFNLNALV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211   111 kiSDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSP-RFHGAEDSFYQSQTPPRHSANQMLFLTGELR 189
Cdd:pfam03934  82 --ADGAPPKDPAALQQFQRLLEALGLDAAQAERLADALADWLDADDDPpSPGGAEDSYYLSLSPPYLPANQPLADVSELR 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211   190 QIKGITENIYQRLIPYVCVLPTTELSINLNMLtenDIPLFRALFLnNITDADARVLLQKRPREGWLTTDAFlyWAQQDFS 269
Cdd:pfam03934 160 LVLGFTPELYARLRPYVCALPGDRTPINVNTA---PAEVLAALFD-GLSLDQAQALLAQRPADGFESVDDF--LAQPALG 233
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 16131211   270 GV-KPLVAQVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQ 314
Cdd:pfam03934 234 GGiAPSTAQLKTLLTVKSSYFLLESRVRVDDARVRLRSLLHRDGGG 279
PulK COG3156
Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular ...
27-315 8.62e-74

Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442390 [Multi-domain]  Cd Length: 307  Bit Score: 229.89  E-value: 8.62e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211  27 MTLSFHSQLQRTRQVNHHLQRQYDIELAEKLALASLTQDvkDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQHCFNL 106
Cdd:COG3156  30 LAERQRLELRRAENLLDRQQARWYALGAEALARARLADD--AKDNVDHLGEPWAQPLPPFPLDGGEVSGRIRDEQGCFNL 107
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211 107 NALakiSDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSPRFHGAEDSFYQSQTPPRHSANQMLFLTG 186
Cdd:COG3156 108 NAL---VDPDGEVNPYAQQVFRRLLEALGLDEYEAEALADAIVDWIDSDDLPRPGGAEDDYYLALGPPYRPANGPFASVS 184
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211 187 ELRQIKGITENIYQRLIPYVCVLPTTeLSINLNMLTEndiPLFRALFLnNITDADARVLLQKRPREGWLTTDAFLYWAQQ 266
Cdd:COG3156 185 ELRLVKGMTPELYARLAPYVTALPGD-TKINVNTAPP---EVLAALLG-GLSLDDAQALLAARPEKGFADVADFLALLGL 259
                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*....
gi 16131211 267 dfsgvkPLVAQVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQQ 315
Cdd:COG3156 260 ------AGLDLLKDQLTVSSDYFLLEATVRLGDGRLRLRSLLQRSGGGG 302
T2SS_GspK NF037980
type II secretion system minor pseudopilin GspK;
27-322 1.79e-71

type II secretion system minor pseudopilin GspK;


Pssm-ID: 468299 [Multi-domain]  Cd Length: 311  Bit Score: 224.09  E-value: 1.79e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211   27 MTLSFHSQLQRTRQVNHHLQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQHCFNL 106
Cdd:NF037980  23 MLERQQLQVRRTENQQAQQQARWYALGAEALARLLLRDDLRDDSDVDHLGQPWAQPLPEFYPEGGQVSGRIEDLQGCFNL 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211  107 NALAKIS-DDPLASPDFPAQVFSALLINAGIDRGNTdeIVQSIADYIDVDDSPRFHG--AEDSFYQSQTPPRHSANQMLF 183
Cdd:NF037980 103 NALVGGGgPDAAAQAPYALRVFQRLLELLGLDAYEA--LADALADWLDADDQPRGPGgaAEDYGYESLSPPYLAANQLLA 180
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211  184 LTGELRQIKGITENIYQRLIPYVCVLPTTELSINLNMLTENDIPLFRALflnnITDADARVLLQKRPREGWLTTDAFlyW 263
Cdd:NF037980 181 DVSELRLVPGVTPALYARLRPYVCALPTTTLAINVNTAPAEVLAALAAL----LSLSQARALLAARPAAGFRSVGDF--L 254
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 16131211  264 AQQDFSGVKpLVAQVKRHLFPYSRYFTLSTESISDEqSQGWQSHIFFNRKQQSAQIYRR 322
Cdd:NF037980 255 AQLALAGLA-LDASDKEQLGVRSRYFLLRGEVRLGE-ARLRLRSLLYRDGVGKVTVVRR 311
 
Name Accession Description Interval E-value
T2SSK pfam03934
Type II secretion system (T2SS), protein K; Members of this family are involved in the Type II ...
31-314 5.77e-80

Type II secretion system (T2SS), protein K; Members of this family are involved in the Type II protein secretion system. The T2SK family includes proteins such as ExeK, PulK, OutX and XcpX.


Pssm-ID: 427597 [Multi-domain]  Cd Length: 283  Bit Score: 244.93  E-value: 5.77e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211    31 FHSQLQRTRQVNHHLQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQHCFNLNALA 110
Cdd:pfam03934   2 QQLQVRRTENLQARQQAYWYALGAEALARQILRDDLRDSPGVDHLDQPWAQPLQPFPLDGGEVSGRIEDLQGCFNLNALV 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211   111 kiSDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSP-RFHGAEDSFYQSQTPPRHSANQMLFLTGELR 189
Cdd:pfam03934  82 --ADGAPPKDPAALQQFQRLLEALGLDAAQAERLADALADWLDADDDPpSPGGAEDSYYLSLSPPYLPANQPLADVSELR 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211   190 QIKGITENIYQRLIPYVCVLPTTELSINLNMLtenDIPLFRALFLnNITDADARVLLQKRPREGWLTTDAFlyWAQQDFS 269
Cdd:pfam03934 160 LVLGFTPELYARLRPYVCALPGDRTPINVNTA---PAEVLAALFD-GLSLDQAQALLAQRPADGFESVDDF--LAQPALG 233
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 16131211   270 GV-KPLVAQVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQ 314
Cdd:pfam03934 234 GGiAPSTAQLKTLLTVKSSYFLLESRVRVDDARVRLRSLLHRDGGG 279
PulK COG3156
Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular ...
27-315 8.62e-74

Type II secretory pathway, component PulK [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442390 [Multi-domain]  Cd Length: 307  Bit Score: 229.89  E-value: 8.62e-74
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211  27 MTLSFHSQLQRTRQVNHHLQRQYDIELAEKLALASLTQDvkDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQHCFNL 106
Cdd:COG3156  30 LAERQRLELRRAENLLDRQQARWYALGAEALARARLADD--AKDNVDHLGEPWAQPLPPFPLDGGEVSGRIRDEQGCFNL 107
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211 107 NALakiSDDPLASPDFPAQVFSALLINAGIDRGNTDEIVQSIADYIDVDDSPRFHGAEDSFYQSQTPPRHSANQMLFLTG 186
Cdd:COG3156 108 NAL---VDPDGEVNPYAQQVFRRLLEALGLDEYEAEALADAIVDWIDSDDLPRPGGAEDDYYLALGPPYRPANGPFASVS 184
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211 187 ELRQIKGITENIYQRLIPYVCVLPTTeLSINLNMLTEndiPLFRALFLnNITDADARVLLQKRPREGWLTTDAFLYWAQQ 266
Cdd:COG3156 185 ELRLVKGMTPELYARLAPYVTALPGD-TKINVNTAPP---EVLAALLG-GLSLDDAQALLAARPEKGFADVADFLALLGL 259
                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*....
gi 16131211 267 dfsgvkPLVAQVKRHLFPYSRYFTLSTESISDEQSQGWQSHIFFNRKQQ 315
Cdd:COG3156 260 ------AGLDLLKDQLTVSSDYFLLEATVRLGDGRLRLRSLLQRSGGGG 302
T2SS_GspK NF037980
type II secretion system minor pseudopilin GspK;
27-322 1.79e-71

type II secretion system minor pseudopilin GspK;


Pssm-ID: 468299 [Multi-domain]  Cd Length: 311  Bit Score: 224.09  E-value: 1.79e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211   27 MTLSFHSQLQRTRQVNHHLQRQYDIELAEKLALASLTQDVKDNDRQTTLQQYWAQPQQLQLEDGNTVKWQLRDAQHCFNL 106
Cdd:NF037980  23 MLERQQLQVRRTENQQAQQQARWYALGAEALARLLLRDDLRDDSDVDHLGQPWAQPLPEFYPEGGQVSGRIEDLQGCFNL 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211  107 NALAKIS-DDPLASPDFPAQVFSALLINAGIDRGNTdeIVQSIADYIDVDDSPRFHG--AEDSFYQSQTPPRHSANQMLF 183
Cdd:NF037980 103 NALVGGGgPDAAAQAPYALRVFQRLLELLGLDAYEA--LADALADWLDADDQPRGPGgaAEDYGYESLSPPYLAANQLLA 180
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131211  184 LTGELRQIKGITENIYQRLIPYVCVLPTTELSINLNMLTENDIPLFRALflnnITDADARVLLQKRPREGWLTTDAFlyW 263
Cdd:NF037980 181 DVSELRLVPGVTPALYARLRPYVCALPTTTLAINVNTAPAEVLAALAAL----LSLSQARALLAARPAAGFRSVGDF--L 254
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 16131211  264 AQQDFSGVKpLVAQVKRHLFPYSRYFTLSTESISDEqSQGWQSHIFFNRKQQSAQIYRR 322
Cdd:NF037980 255 AQLALAGLA-LDASDKEQLGVRSRYFLLRGEVRLGE-ARLRLRSLLYRDGVGKVTVVRR 311
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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