|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
1-471 |
0e+00 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 945.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 1 MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGS 80
Cdd:PRK08006 1 MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 81 PIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL 160
Cdd:PRK08006 81 PIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGYDPQGRTSEDLLDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 161 AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTF 240
Cdd:PRK08006 161 AESRVFQIAESRANKDEGPKNIADILDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 241 AMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTP 320
Cdd:PRK08006 241 AMNLCENAAMLQDKPVLIFSLEMPGEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGTMGILLEKRNMYIDDSSGLTP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 321 TEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNS 400
Cdd:PRK08006 321 TEVRSRARRIFREHGGLSLIMIDYLQLMRVPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNS 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16131878 401 DLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE 471
Cdd:PRK08006 401 DLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE 471
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
27-464 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 751.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 27 PPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYL 106
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 107 AELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGrTSEDLLDLAESRVFKIAESRanKDEGPKNIADVL 186
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTG-DVEELLDEAEQKIFEIAESR--TSKGFKSIKEIL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 187 DATVARIEQLFQQPhDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSE 266
Cdd:TIGR00665 158 KEAVEEIEELYERK-GGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 267 QIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKrNIYIDDSSGLTPTEVRSRARRIAREHGgIGLIMIDYLQ 346
Cdd:TIGR00665 237 QLVMRMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEA-PLYIDDTPGLTITELRAKARRLKREHG-LGLIVIDYLQ 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 347 LMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHE 426
Cdd:TIGR00665 315 LMSGSGRSENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNP 394
|
410 420 430
....*....|....*....|....*....|....*...
gi 16131878 427 NSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYA 464
Cdd:TIGR00665 395 DSEDKGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
30-464 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 724.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 30 SIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAEL 109
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 110 SKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQgRTSEDLLDLAESRVFKIAESRANKdeGPKNIADVLDAT 189
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDED-EDVDELLDEAEQKIFEIAEKRSSK--GFVSISDILKEA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 190 VARIEQLFQQPhDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIM 269
Cdd:COG0305 158 LERIEELYKNG-GGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 270 MRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILlEKRNIYIDDSSGLTPTEVRSRARRIAREHGgIGLIMIDYLQLMR 349
Cdd:COG0305 237 MRLLSSEARIDSSKLRTGKLSDEDWERLSSAAGEL-SEAPIYIDDTPGLTIAEIRAKARRLKREHG-LGLIVIDYLQLMS 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 350 VPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSD 429
Cdd:COG0305 315 GSGRSENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPDSE 394
|
410 420 430
....*....|....*....|....*....|....*
gi 16131878 430 LKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYA 464
Cdd:COG0305 395 DKGIAEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
27-463 |
0e+00 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 655.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 27 PPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYL 106
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 107 AELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSeDLLDLAESRVFKIAESRAnkDEGPKNIADVL 186
Cdd:NF040583 81 AELSKNTPSAANIVAYAEIVAEYSRARQLLALGHDLSADASAPRADIA-DLLEQAEQRLFDIAEQAE--PQQEVTLIEGL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 187 DATVARIEQLFQQPhDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAM-LQDKPVLIFSLEMPS 265
Cdd:NF040583 158 ETLVSELELRCQSG-NGITGTPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGALRgKPDKVVQIYSLEMPT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 266 EQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRN-IYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDY 344
Cdd:NF040583 237 EQLLMRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTDWKDrLIIDDTSYLTPALLRARARRNARKYGKPSLIMVDY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 345 LQLMRVPAlSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVY 424
Cdd:NF040583 317 LQLMRCPG-QENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIYRDEVY 395
|
410 420 430
....*....|....*....|....*....|....*....
gi 16131878 425 HENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNY 463
Cdd:NF040583 396 NPNTPDKGIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
206-462 |
2.87e-165 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 466.12 E-value: 2.87e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 206 GVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIR 285
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 286 TGQLDDEDWARISGTMGILlEKRNIYIDDSSGLTPTEVRSRARRIAREHGgIGLIMIDYLQLMRVPALSDNRTLEIAEIS 365
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRL-SEAPLYIDDTPGLSIAEIRAKARRLKREHG-LGLIVIDYLQLMSGGSRGENRQQEISEIS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 366 RSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHEnSDLKGIAEIIIGKQRNGP 445
Cdd:pfam03796 159 RSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNP-KEPEGKAEIIIAKQRNGP 237
|
250
....*....|....*..
gi 16131878 446 IGTVRLTFNGQWSRFDN 462
Cdd:pfam03796 238 TGTVKLAFLGEYTRFEN 254
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
206-462 |
1.55e-158 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 448.88 E-value: 1.55e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 206 GVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIR 285
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 286 TGQLDDEDWARISGTMGILLEKrNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEIS 365
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSEL-PLYIDDTPGLTVDEIRAKARRLKREHGGLGLIVIDYLQLIRGSKRAENRQQEVAEIS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 366 RSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGP 445
Cdd:cd00984 160 RSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGP 239
|
250
....*....|....*..
gi 16131878 446 IGTVRLTFNGQWSRFDN 462
Cdd:cd00984 240 TGTVYLAFNPEYTRFTD 256
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08006 |
PRK08006 |
replicative DNA helicase DnaB; |
1-471 |
0e+00 |
|
replicative DNA helicase DnaB;
Pssm-ID: 181193 [Multi-domain] Cd Length: 471 Bit Score: 945.98 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 1 MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGS 80
Cdd:PRK08006 1 MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 81 PIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL 160
Cdd:PRK08006 81 PIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIADAGYDPQGRTSEDLLDL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 161 AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTF 240
Cdd:PRK08006 161 AESRVFQIAESRANKDEGPKNIADILDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 241 AMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTP 320
Cdd:PRK08006 241 AMNLCENAAMLQDKPVLIFSLEMPGEQIMMRMLASLSRVDQTRIRTGQLDDEDWARISGTMGILLEKRNMYIDDSSGLTP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 321 TEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNS 400
Cdd:PRK08006 321 TEVRSRARRIFREHGGLSLIMIDYLQLMRVPSLSDNRTLEIAEISRSLKALAKELQVPVVALSQLNRSLEQRADKRPVNS 400
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16131878 401 DLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE 471
Cdd:PRK08006 401 DLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE 471
|
|
| PRK08840 |
PRK08840 |
replicative DNA helicase; Provisional |
14-471 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181562 [Multi-domain] Cd Length: 464 Bit Score: 829.25 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 14 PRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLER 93
Cdd:PRK08840 7 RKIPDAQVDAIKVPPHSLEAEQSVIGGLLLDNERWDTVAEKVVASDFYSRPHRLIFEGVKSILEAGKPLDLITLSEHLER 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 94 QGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRA 173
Cdd:PRK08840 87 REQLEDVGGFAYLADLAKNTPSAANINAYADIVAERALVRNLIGVANEIADAGYDPQGRTSEDLLDMAESKVFAIAEART 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 174 NKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQD 253
Cdd:PRK08840 167 SENEGPQNVDSILEKTLERIELLYKTPQDGVTGVDTGFTDLNKKTAGLQGSDLIIVAARPSMGKTTFAMNLCENAAMDQD 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 254 KPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIARE 333
Cdd:PRK08840 247 KPVLIFSLEMPAEQLMMRMLASLSRVDQTKIRTGQLDDEDWARISSTMGILMEKKNMYIDDSSGLTPTEVRSRARRIARE 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 334 HGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDAD 413
Cdd:PRK08840 327 HGGLSMIMVDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDAD 406
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*...
gi 16131878 414 LIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE 471
Cdd:PRK08840 407 LIMFIYRDEVYNPDSPLKGTAEIIIGKQRNGPIGSVRLTFQGQYSRFDNYAGPAFDDE 464
|
|
| DnaB |
TIGR00665 |
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein ... |
27-464 |
0e+00 |
|
replicative DNA helicase; This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273206 [Multi-domain] Cd Length: 432 Bit Score: 751.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 27 PPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYL 106
Cdd:TIGR00665 1 PPHNIEAEQAVLGAILLDNEAIDDVAEILKPEDFYRPAHRLIFQAILDLYEKGEPIDLVTVAEELEKDGELEEVGGLAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 107 AELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGrTSEDLLDLAESRVFKIAESRanKDEGPKNIADVL 186
Cdd:TIGR00665 81 AELASNVPSAANIEYYAEIVKEKAILRRLIQAGTEIVELAYDPTG-DVEELLDEAEQKIFEIAESR--TSKGFKSIKEIL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 187 DATVARIEQLFQQPhDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSE 266
Cdd:TIGR00665 158 KEAVEEIEELYERK-GGITGVPTGFTDLDKLTSGLQPSDLIILAARPSMGKTAFALNIAENAAIKEGKPVAFFSLEMSAE 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 267 QIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKrNIYIDDSSGLTPTEVRSRARRIAREHGgIGLIMIDYLQ 346
Cdd:TIGR00665 237 QLVMRMLSSESRVDSQKLRTGRLSDEDWEKLTEAAGELSEA-PLYIDDTPGLTITELRAKARRLKREHG-LGLIVIDYLQ 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 347 LMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHE 426
Cdd:TIGR00665 315 LMSGSGRSENRQQEVSEISRSLKALAKELNVPVIALSQLSRSVEQREDKRPQLSDLRESGSIEQDADIVMFLYRDEYYNP 394
|
410 420 430
....*....|....*....|....*....|....*...
gi 16131878 427 NSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYA 464
Cdd:TIGR00665 395 DSEDKGIAEIIIAKQRNGPTGTVKLAFLGEYTRFENLA 432
|
|
| PRK06904 |
PRK06904 |
replicative DNA helicase; Validated |
11-471 |
0e+00 |
|
replicative DNA helicase; Validated
Pssm-ID: 136106 [Multi-domain] Cd Length: 472 Bit Score: 739.89 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 11 QAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAES 90
Cdd:PRK06904 7 QQSARIKDKKTAQVLIPPHSIEAEQAVLGGIMLDNRHWDSVAERVIADDFYTFEHRIIFQEMELLFRQNTPIDLLTLDQA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 91 LERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAE 170
Cdd:PRK06904 87 LKTKGKSDEVGGFAYLAELSNNTPSAANILAYADIVREKAILRELISVGNNIAKNAYSPKGQDIKDILDEAERDVFSIAE 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 171 SRANKDEGPKNIADVLDATVARIEQLFQQP-HDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAA 249
Cdd:PRK06904 167 KRTTANEGPQNVINLLENTIDKIENLAATPtNNGVTGVTTGFTDLDKKTAGLQPSDLIIVAARPSMGKTTFAMNLCENAA 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 250 MLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQ-LDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRAR 328
Cdd:PRK06904 247 MASEKPVLVFSLEMPAEQIMMRMLASLSRVDQTKIRTGQnLDQQDWAKISSTVGMFKQKPNLYIDDSSGLTPTELRSRAR 326
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 329 RIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSI 408
Cdd:PRK06904 327 RVYRENGGLSLIMVDYLQLMRAPGFEDNRTLEIAEISRSLKALAKELKVPVVALSQLNRTLENRGDKRPVNSDLRESGSI 406
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 16131878 409 EQDADLIMFIYRDEVYHENS-DLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAG-PQYDDE 471
Cdd:PRK06904 407 EQDADLIMFIYRDEVYNETTeDNKGVAEIIIGKQRNGPIGRVRLAFQGQYSRFDNLANiPQYYDK 471
|
|
| DnaB |
COG0305 |
Replicative DNA helicase [Replication, recombination and repair]; |
30-464 |
0e+00 |
|
Replicative DNA helicase [Replication, recombination and repair];
Pssm-ID: 440074 [Multi-domain] Cd Length: 429 Bit Score: 724.56 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 30 SIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAEL 109
Cdd:COG0305 1 NIEAEQAVLGALLLDNDALDEVADILKPEDFYRPAHRLIFEAILDLYERGEPIDLVTVAEELEKRGELEEVGGAAYLAEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 110 SKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQgRTSEDLLDLAESRVFKIAESRANKdeGPKNIADVLDAT 189
Cdd:COG0305 81 AENVPSAANIEYYARIVKEKALLRRLIEAGTEIVELAYDED-EDVDELLDEAEQKIFEIAEKRSSK--GFVSISDILKEA 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 190 VARIEQLFQQPhDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIM 269
Cdd:COG0305 158 LERIEELYKNG-GGITGVPTGFTDLDKLTGGLQPGDLIILAARPSMGKTAFALNIARNAAIKEGKPVAIFSLEMSAEQLV 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 270 MRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILlEKRNIYIDDSSGLTPTEVRSRARRIAREHGgIGLIMIDYLQLMR 349
Cdd:COG0305 237 MRLLSSEARIDSSKLRTGKLSDEDWERLSSAAGEL-SEAPIYIDDTPGLTIAEIRAKARRLKREHG-LGLIVIDYLQLMS 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 350 VPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSD 429
Cdd:COG0305 315 GSGRSENRQQEISEISRSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGSIEQDADVVMFLYRDEYYNPDSE 394
|
410 420 430
....*....|....*....|....*....|....*
gi 16131878 430 LKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYA 464
Cdd:COG0305 395 DKGIAEIIIAKQRNGPTGTVKLAFDGEYTRFENLA 429
|
|
| PRK05748 |
PRK05748 |
replicative DNA helicase; Provisional |
18-469 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180232 [Multi-domain] Cd Length: 448 Bit Score: 694.39 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 18 DPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQL 97
Cdd:PRK05748 1 MSEVAALRVPPQSIEAEQAVLGAIFLDPDALITVSEYLSPDDFYRHAHRLIFRAMLKLSDRGEPIDVVTVTEILDDQGDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 98 DSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGrTSEDLLDLAESRVFKIAESRANKde 177
Cdd:PRK05748 81 EEVGGLSYLAELANSVPTAANIEYYAKIVAEKAMLRRLIRTATEIANDAYEPED-DADEILDEAEKKIFEVSERRNKS-- 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 178 GPKNIADVLDATVARIEQLFQQPHDgVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVL 257
Cdd:PRK05748 158 GFKNIKDVLVKAYDRIEMLHNQTGD-ITGIPTGFTDLDKMTSGLQPNDLIIVAARPSVGKTAFALNIAQNVATKTDKNVA 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 258 IFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGiLLEKRNIYIDDSSGLTPTEVRSRARRIAREHGGI 337
Cdd:PRK05748 237 IFSLEMGAESLVMRMLCAEGNIDAQRLRTGQLTDDDWPKLTIAMG-SLSDAPIYIDDTPGIKVTEIRARCRRLAQEHGGL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 338 GLIMIDYLQLMRVPALS-DNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIM 416
Cdd:PRK05748 316 GLILIDYLQLIQGSGRSgENRQQEVSEISRSLKALAKELKVPVIALSQLSRGVEQRQDKRPVMSDIRESGSIEQDADIVA 395
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 16131878 417 FIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYD 469
Cdd:PRK05748 396 FLYRDDYYDEETENKNTIEIIIAKQRNGPVGTVELAFQKEYNKFVNLARREED 448
|
|
| dnaB_SPI-7_type |
NF040583 |
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a ... |
27-463 |
0e+00 |
|
SPI-7-type island replicative DNA helicase; Members of this family are DnaB-PI, a pathogenicity island (PI) variant of the replicative DNA helicase DnaB. Members are found with other conjugative element replication proteins such as ParA, ParB in genetic islands whose core proteins (but not cargo proteins) are shared with the Salmonella typhi SPI-7 island.
Pssm-ID: 468557 [Multi-domain] Cd Length: 434 Bit Score: 655.15 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 27 PPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYL 106
Cdd:NF040583 1 GPYSVEAEQSVLGGLMLDNDRWDDVALLLAADDFYSRAHRIIFRAMARLVSAGQPIDLITLSESLEQQGQLEQVGGFAYL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 107 AELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSeDLLDLAESRVFKIAESRAnkDEGPKNIADVL 186
Cdd:NF040583 81 AELSKNTPSAANIVAYAEIVAEYSRARQLLALGHDLSADASAPRADIA-DLLEQAEQRLFDIAEQAE--PQQEVTLIEGL 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 187 DATVARIEQLFQQPhDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAM-LQDKPVLIFSLEMPS 265
Cdd:NF040583 158 ETLVSELELRCQSG-NGITGTPTGFAELDEMTCGLQPGDLILLAARPSMGKTALALAFCLGALRgKPDKVVQIYSLEMPT 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 266 EQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRN-IYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDY 344
Cdd:NF040583 237 EQLLMRLVSMLGRVPLQRLRSGLLDDEDWARISQAMALLTDWKDrLIIDDTSYLTPALLRARARRNARKYGKPSLIMVDY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 345 LQLMRVPAlSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVY 424
Cdd:NF040583 317 LQLMRCPG-QENRTQEIAEISRSLKALAKEMGCPVLALSQLNRQLESRADKRPNNGDLRDSGALEQDADLIMFIYRDEVY 395
|
410 420 430
....*....|....*....|....*....|....*....
gi 16131878 425 HENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNY 463
Cdd:NF040583 396 NPNTPDKGIAEIIIGKQRQGPTGTVKVQFDGRYTRFSDL 434
|
|
| PRK07004 |
PRK07004 |
replicative DNA helicase; Provisional |
16-470 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235907 [Multi-domain] Cd Length: 460 Bit Score: 569.54 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 16 ERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQG 95
Cdd:PRK07004 4 PADPQLESLKVPPHSIEAEQSVLGGLLLDNAAWDRIADFLSQSDFYRYDHRIIFEHIGRLIAATRPADVITVYEALTTSG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 96 QLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRANK 175
Cdd:PRK07004 84 KAEEVGGLAYLNALAQNTPSAANIRRYAEIVRDRAVLRRLVSVADEISADAFNPQGKEVRQLLDEAESKVFSIAEEGARG 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 176 DEGPKNIADVLDATVARIEQLFQQPHDG-VTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDK 254
Cdd:PRK07004 164 TQGFLEIGPLLTQVVERIDTLYHTANPSdVTGTPTGFVDLDRMTSGMHGGELIIVAGRPSMGKTAFSMNIGEYVAVEYGL 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 255 PVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGiLLEKRNIYIDDSSGLTPTEVRSRARRIAREH 334
Cdd:PRK07004 244 PVAVFSMEMPGTQLAMRMLGSVGRLDQHRMRTGRLTDEDWPKLTHAVQ-KMSEAQLFIDETGGLNPMELRSRARRLARQC 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 335 GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADL 414
Cdd:PRK07004 323 GKLGLIIIDYLQLMSGSSQGENRATEISEISRSLKSLAKELDVPVIALSQLNRGLEQRPNKRPVMSDLRESGAIEQDADV 402
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 16131878 415 IMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAG-PQYDD 470
Cdd:PRK07004 403 ILFIYRDEVYNPDSPDKGTAEIIIGKQRNGPIGPVRLTFLGQYTKFDNFAGaQNFYG 459
|
|
| PRK08760 |
PRK08760 |
replicative DNA helicase; Provisional |
1-464 |
0e+00 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181547 [Multi-domain] Cd Length: 476 Bit Score: 524.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 1 MAGNKPFNKQQAEPRERD------PQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMAR 74
Cdd:PRK08760 1 MSARPGFRSNRNRDRDDDdydrpePRLDQLRVPPHSVEAEQAVLGGLMLAPDALDRVNDQLTENDFYRRDHRLIYRAIRE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 75 LQESGSPIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTS 154
Cdd:PRK08760 81 LSEKDRPFDAVTLGEWFESQGKLEQVGDGAYLIELASTTPSAANIAAYAEIVRDKAVLRQLIEVGTTIVNDGFQPEGRES 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 155 EDLLDLAESRVFKIAESRAnkdEGPKNIADVLDATVARIEQLFQQPHDG--VTGVNTGYDDLNKKTAGLQPSDLIIVAAR 232
Cdd:PRK08760 161 IELLASAEKAVFKIAEAGA---RGRTDFVAMPGALKDAFEELRNRFENGgnITGLPTGYNDFDAMTAGLQPTDLIILAAR 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 233 PSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRnIYI 312
Cdd:PRK08760 238 PAMGKTTFALNIAEYAAIKSKKGVAVFSMEMSASQLAMRLISSNGRINAQRLRTGALEDEDWARVTGAIKMLKETK-IFI 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 313 DDSSGLTPTEVRSRARRIAREHgGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR 392
Cdd:PRK08760 317 DDTPGVSPEVLRSKCRRLKREH-DLGLIVIDYLQLMSVPGNSENRATEISEISRSLKGLAKELNVPVIALSQLNRSLETR 395
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16131878 393 ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYH-ENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYA 464
Cdd:PRK08760 396 TDKRPVMADLRESGAIEQDADMIVFIYRDDYYNkENSPDKGLAEIIIGKHRGGPTGSCKLKFFGEYTRFDNLA 468
|
|
| DnaB_C |
pfam03796 |
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
206-462 |
2.87e-165 |
|
DnaB-like helicase C terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 427509 [Multi-domain] Cd Length: 254 Bit Score: 466.12 E-value: 2.87e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 206 GVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIR 285
Cdd:pfam03796 1 GLPTGFTDLDRLTGGLQPGDLIIIAARPSMGKTAFALNIARNAAVKHKKPVAIFSLEMSAEQLVMRLLASEAGVDSQKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 286 TGQLDDEDWARISGTMGILlEKRNIYIDDSSGLTPTEVRSRARRIAREHGgIGLIMIDYLQLMRVPALSDNRTLEIAEIS 365
Cdd:pfam03796 81 TGQLTDEDWEKLAKAAGRL-SEAPLYIDDTPGLSIAEIRAKARRLKREHG-LGLIVIDYLQLMSGGSRGENRQQEISEIS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 366 RSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHEnSDLKGIAEIIIGKQRNGP 445
Cdd:pfam03796 159 RSLKALAKELNVPVIALSQLSRAVEQRTDKRPQLSDLRESGAIEQDADVVMFLYRDEYYNP-KEPEGKAEIIIAKQRNGP 237
|
250
....*....|....*..
gi 16131878 446 IGTVRLTFNGQWSRFDN 462
Cdd:pfam03796 238 TGTVKLAFLGEYTRFEN 254
|
|
| phage_DnaB |
TIGR03600 |
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or ... |
30-453 |
1.24e-163 |
|
phage replicative helicase, DnaB family, HK022 subfamily; Members of this family are phage (or prophage-region) homologs of the bacterial homohexameric replicative helicase DnaB. Some phage may rely on host DnaB, while others encode their own verions. This model describes the largest phage-specific clade among the close homologs of DnaB, but there are, or course, other DnaB homologs from phage that fall outside the scope of this model. [Mobile and extrachromosomal element functions, Prophage functions]
Pssm-ID: 274672 [Multi-domain] Cd Length: 420 Bit Score: 468.42 E-value: 1.24e-163
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 30 SIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAEL 109
Cdd:TIGR03600 1 SIEAEQAVLGGLLLDNDFIERVMAILKPEHFYSQDHRIIFEAMLDMFAENRPVDPLTLADKLEAEGEAEKVGGLAYLAEI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 110 SKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDLAESRVFKIAESRANKDeGPKNIADVLDAT 189
Cdd:TIGR03600 81 SNNTPSAANISSYARIVREKAKERKLIAACQRIITLACSPDGGTAEQKVEEAQAALLALTMSDGQED-GFVTFGEVLEDV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 190 VARIEQLFQqPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIM 269
Cdd:TIGR03600 160 VRDLDKRFN-PKGELTGLSTGLPKLDRLTNGLVKGDLIVIGARPSMGKTTLALNIAENVALREGKPVLFFSLEMSAEQLG 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 270 MRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKrNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMR 349
Cdd:TIGR03600 239 ERLLASKSGINTGNIRTGRFNDSEFNRLLNAVDRLSEK-DLYIDDTGGLTVAQIRSIARRIKRKKGGLDLIVVDYIQLMA 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 350 vPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSD 429
Cdd:TIGR03600 318 -PARGRDRNEELGGISRGLKALAKELDVPVVLLAQLNRGSEKRTDKRPIMSDLRDSGAIEQDADVIGLIHREGYYDAREP 396
|
410 420
....*....|....*....|....
gi 16131878 430 LKGIAEIIIGKQRNGPIGTVRLTF 453
Cdd:TIGR03600 397 PAGIAELILAKNRHGPTGTVELLF 420
|
|
| PRK05595 |
PRK05595 |
replicative DNA helicase; Provisional |
22-463 |
1.32e-161 |
|
replicative DNA helicase; Provisional
Pssm-ID: 235525 [Multi-domain] Cd Length: 444 Bit Score: 464.30 E-value: 1.32e-161
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 22 AGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVG 101
Cdd:PRK05595 3 APIRSLPQSIEAEQSVLGAMIIDKTSIAEAAEVLKSEDFYRDSHKVIFSAIIELYQKDIAVDMLTLTENLKSTDKLEAAG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 102 GFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTsEDLLDLAESRVFKIAESRANKDEGPkn 181
Cdd:PRK05595 83 GVTYITELSNSIVSTANIQSYIKIVKDKSTLRRLIKSSTEIIENSYNNQDDV-EKVIDSAEKKIFDISEKRTTSDFEP-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 182 IADVLDATVARIEQLFQQpHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSL 261
Cdd:PRK05595 160 LSNVLERGFEQIENLFNN-KGETTGVASGFRELDAKTSGFQKGDMILIAARPSMGKTTFALNIAEYAALREGKSVAIFSL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 262 EMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILlEKRNIYIDDSSGLTPTEVRSRARRIAREHGgIGLIM 341
Cdd:PRK05595 239 EMSKEQLAYKLLCSEANVDMLRLRTGNLEDKDWENIARASGPL-AAAKIFIDDTAGVSVMEMRSKCRRLKIEHG-IDMIL 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 342 IDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRD 421
Cdd:PRK05595 317 IDYLQLMSGGKGSESRQQEVSEISRSIKALAKEMECPVIALSQLSRAPEQRADHRPMLSDLRESGSIEQDADVVMFLYRD 396
|
410 420 430 440
....*....|....*....|....*....|....*....|..
gi 16131878 422 EVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNY 463
Cdd:PRK05595 397 EYYNKETEDKNVAECIIAKQRNGPTGTVKLAWLGQYSKFGNL 438
|
|
| DnaB_C |
cd00984 |
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase ... |
206-462 |
1.55e-158 |
|
C-terminal domain of DnaB helicase; DnaB helicase C-terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Pssm-ID: 410864 [Multi-domain] Cd Length: 256 Bit Score: 448.88 E-value: 1.55e-158
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 206 GVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIR 285
Cdd:cd00984 1 GLPTGFTDLDKLTGGLQPGDLIIIAARPSMGKTAFALNIAENIALDEGLPVLFFSLEMSAEQLAERLLSSESGVSLSKLR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 286 TGQLDDEDWARISGTMGILLEKrNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEIS 365
Cdd:cd00984 81 TGRLDDEDWERLTAAMGELSEL-PLYIDDTPGLTVDEIRAKARRLKREHGGLGLIVIDYLQLIRGSKRAENRQQEVAEIS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 366 RSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGP 445
Cdd:cd00984 160 RSLKALAKELNVPVIALSQLNRGVESRTDKRPMLSDLRESGSIEQDADVVIFLYRDEYYDKDSEDKGIAEIIIAKNRNGP 239
|
250
....*....|....*..
gi 16131878 446 IGTVRLTFNGQWSRFDN 462
Cdd:cd00984 240 TGTVYLAFNPEYTRFTD 256
|
|
| PRK09165 |
PRK09165 |
replicative DNA helicase; Provisional |
14-471 |
2.75e-156 |
|
replicative DNA helicase; Provisional
Pssm-ID: 181676 [Multi-domain] Cd Length: 497 Bit Score: 452.80 E-value: 2.75e-156
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 14 PRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLER 93
Cdd:PRK09165 8 DLAPDAAEPEIRELPHNIEAEQALLGAILINNRALDRVSDFLKPEHFFEPLHQRIYEAIAKIIRKGKLATPVTLKTFLEN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 94 QGQLDSVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFD-PQGRTSEDLLDLAESRVFKIAESR 172
Cdd:PRK09165 88 DEALGELGGVQYLAKLATEAVTIINARDYGRIIYDLALRRELINIGEDVVNNAYDaPVDVAPQEQIEDAEQKLYELAETG 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 173 ANkDEGPKNIADVLDATVARIEQLFQQPhDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAA--- 249
Cdd:PRK09165 168 RY-EGGFQSFGTAITEAVDMANAAFKRD-GHLSGISTGLRDLDSKLGGLHPSDLIILAGRPSMGKTALATNIAFNAAkay 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 250 ---MLQD--------KPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMgILLEKRNIYIDDSSGL 318
Cdd:PRK09165 246 rreAQPDgskkavngGVVGFFSLEMSAEQLATRILSEQSEISSSKIRRGKISEEDFEKLVDAS-QELQKLPLYIDDTPAL 324
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 319 TPTEVRSRARRIAREHGgIGLIMIDYLQLMRVPAL--SDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKR 396
Cdd:PRK09165 325 SISQLRARARRLKRQHG-LDLLVVDYLQLIRGSSKrsSDNRVQEISEITQGLKALAKELNIPVIALSQLSRQVEQRDDKR 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 397 PVNSDLRESGSIEQDADLIMFIYRDEVYHENSD-----------------LKGIAEIIIGKQRNGPIGTVRLTFNGQWSR 459
Cdd:PRK09165 404 PQLSDLRESGSIEQDADVVMFVYREEYYLKRKEpregtpkheewqekmekVHNKAEVIIAKQRHGPTGTVKLAFESEFTR 483
|
490
....*....|..
gi 16131878 460 FDNYAGPQYDDE 471
Cdd:PRK09165 484 FGDLADRSQLPE 495
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
25-411 |
1.98e-140 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 424.93 E-value: 1.98e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 25 KVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFA 104
Cdd:PRK07773 22 RQPPQDLAAEQSVLGGMLLSKEAIARVLERLRPGAFYRPAHQNIYDAILDLYGRGEPADLVTVAAELDRRGLLERIGGAP 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 105 YLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPqGRTSEDLLDLAESRVFKIAESRANKDEGPknIAD 184
Cdd:PRK07773 102 YLHTLISTVPTAANADYYARIVAEKALLRRLIEAGTRIVQYGYAE-GADVAEVVDRAQAEIYDVTDRRLSEDFVA--LED 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 185 VLDATVARIEQLFQQPhDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMP 264
Cdd:PRK07773 179 LLQPTFDEIDAIASSG-GLARGVPTGFTELDAMTNGLHPGQLIIVAARPSMGKTTFGLDFARNCAIRHRLAVAIFSLEMS 257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 265 SEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKrNIYIDDSSGLTPTEVRSRARRIAREHgGIGLIMIDY 344
Cdd:PRK07773 258 KEQLVMRLLSAEAKIKLSDMRSGRMSDDDWTRLARAMGEISEA-PIFIDDTPNLTVMEIRAKARRLRQEA-NLGLIVVDY 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 16131878 345 LQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQD 411
Cdd:PRK07773 336 LQLMTSGKKYENRQQEVSEISRHLKLLAKELEVPVVALSQLSRGVEQRTDKRPMLSDLRESGCLTGD 402
|
|
| PRK08506 |
PRK08506 |
replicative DNA helicase; Provisional |
29-460 |
3.24e-140 |
|
replicative DNA helicase; Provisional
Pssm-ID: 236278 [Multi-domain] Cd Length: 472 Bit Score: 410.94 E-value: 3.24e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 29 HSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYLAe 108
Cdd:PRK08506 5 YDLDIERAVLSSILFSPDKFEEIASVLEPKDFYLPAHQDIFEAMLKLHNEDEPIDEEFIRKKLPKDKKIDEEILLEILA- 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 109 lsknTPSAANISAYADIVRERAVVREMISVANEIAEAGFDpQGRTSEDLLDLAESRVFKIAESRANKDEgpKNIADVLDA 188
Cdd:PRK08506 84 ----TNPIDNIEAYVEEIKEKSIKRELLSLANTIPEQAVE-EDQKSSDILDEVERELYSITNGSNSEDF--KDSKEVIES 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 189 TVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMlQDKPVLIFSLEMPSEQI 268
Cdd:PRK08506 157 TMEHIKKQKRLGNKDIIGLDTGFVELNKMTKGFNKGDLIIIAARPSMGKTTLCLNMALKALN-QDKGVAFFSLEMPAEQL 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 269 MMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGiLLEKRNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQLM 348
Cdd:PRK08506 236 MLRMLSAKTSIPLQNLRTGDLDDDEWERLSDACD-ELSKKKLFVYDSGYVNIHQVRAQLRKLKSQHPEIGLAVIDYLQLM 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 349 RVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENS 428
Cdd:PRK08506 315 SGSGNFKDRHLQISEISRGLKLLARELDIPIIALSQLNRSLESRADKRPMLSDLRESGAIEQDADIILFVYRDDVYKERE 394
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 16131878 429 D--------LKGI--------------AEIIIGKQRNGPIGTVRLTFNGQWSRF 460
Cdd:PRK08506 395 EkekekkakKEGKeerrihfqnksieeAEIIIGKNRNGPTGTVKLRFQKEFTRF 448
|
|
| PRK05636 |
PRK05636 |
replicative DNA helicase; Provisional |
27-464 |
3.46e-126 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180177 [Multi-domain] Cd Length: 505 Bit Score: 376.10 E-value: 3.46e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 27 PPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAYL 106
Cdd:PRK05636 70 PPYDNEAEQGVLGAMLLSPDTVIDIVEVLTPEDFYRPAHQLIFQAIIDLFSDNKEIDPVIVAGRLDRTNDLERVGGAPYL 149
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 107 AELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFD-PQGRTSEDLLDLAESRVFKIAESRANKDEgpKNIADV 185
Cdd:PRK05636 150 HTLIQSVPTAANARYYAEIVSEKAVLRRLVDAGTRVVQLGYEgDEGAEIDSVIDRAQQEVFAVSQKNQSEDY--AVLADI 227
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 186 LDATVARIEQLfqQPHDGV-TGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMP 264
Cdd:PRK05636 228 LDPTMDELEML--SSQGGIaTGIPTGFKDLDDLTNGLRGGQMIIVAARPGVGKSTLALDFMRSASIKHNKASVIFSLEMS 305
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 265 SEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGiLLEKRNIYIDDSSGLTPTEVRSRARRIAREHGgIGLIMIDY 344
Cdd:PRK05636 306 KSEIVMRLLSAEAEVRLSDMRGGKMDEDAWEKLVQRLG-KIAQAPIFIDDSANLTMMEIRSKARRLKQKHD-LKLIVVDY 383
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 345 LQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVY 424
Cdd:PRK05636 384 LQLMSSGKRVESRQQEVSEFSRQLKLLAKELDVPLIAISQLNRGPESRTDKRPQLADLRESGSLEQDADMVMLLYRPDSQ 463
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 16131878 425 HENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYA 464
Cdd:PRK05636 464 DKDDERAGEADIILAKHRGGPIDTVQVAHQLHYSRFVDMA 503
|
|
| PRK06321 |
PRK06321 |
replicative DNA helicase; Provisional |
19-469 |
5.30e-121 |
|
replicative DNA helicase; Provisional
Pssm-ID: 180528 [Multi-domain] Cd Length: 472 Bit Score: 361.85 E-value: 5.30e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 19 PQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLD 98
Cdd:PRK06321 8 PQPTQLLSPPNSKESEMIVLGCMLTSVNYLNLAANQLQEDDFYFLEHKIIFRVLQDAFKSDKPIDVHLAGEELKRRNQLN 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 99 SVGGFAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDpQGRTSEDLLDLAESRVFKIAESR------ 172
Cdd:PRK06321 88 VIGGPSYLITLAEFAGTSAYIEEYAEIIRSKSILRKMIQTAKEIEKKALE-EPKDVATALDEAQNLLFKISQTTnlaqyv 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 173 --ANKDEGPKNIADV--LDATVARIEQLFQQPHD----GVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNL 244
Cdd:PRK06321 167 lvADKLKGLTSSKDKpfLLQLQERQEAFQQSAQGdsspMISGIPTHFIDLDKMINGFSPSNLMILAARPAMGKTALALNI 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 245 VENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGiLLEKRNIYIDDSSGLTPTEVR 324
Cdd:PRK06321 247 AENFCFQNRLPVGIFSLEMTVDQLIHRIICSRSEVESKKISVGDLSGRDFQRIVSVVN-EMQEHTLLIDDQPGLKITDLR 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 325 SRARRIAREHGgIGLIMIDYLQLMRVPAL---SDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSD 401
Cdd:PRK06321 326 ARARRMKESYD-IQFLIIDYLQLLSGSGNlrnSESRQTEISEISRMLKNLARELNIPILCLSQLSRKVEDRANHRPMMSD 404
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 16131878 402 LRESGSIEQDADLIMFIYRDEVYHENsDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYD 469
Cdd:PRK06321 405 LRESGSIEQDSDLVMFLLRREYYDPN-DKPGTAELIVAKNRHGSIGSVPLVFEKEFARFRNYAACEFP 471
|
|
| PRK06749 |
PRK06749 |
replicative DNA helicase; Provisional |
30-462 |
2.23e-99 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168658 [Multi-domain] Cd Length: 428 Bit Score: 304.95 E-value: 2.23e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 30 SIEAEQSVLGGLMLDNERWDDVaeRVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLErQGQLDSVGGFAYLAEL 109
Cdd:PRK06749 5 NVEAEKTVLGSLLLDGELIKEC--RLTEQYFSMPVHKSIFQLMRKMEDEGQPIDLVTFTSRVD-PNFLKGIGGMEYFIGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 110 SKNTPSAANISAYADIVRERAVVREMISVANEIAEagfdpQGRTSEDLLDLAESrvfkIAESRANKDEGPKNIADVLDAT 189
Cdd:PRK06749 82 MDGVPTTSNFSYYEGLVRGAWKMYQAGVLGHKMGE-----RLIAEKSEKIIGET----ITALCELEEKDCVCEFDLKDAL 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 190 VARIEQLFQQPHDgVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTFAMNLVENAAMlQDKPVLIFSLEMPSEQIM 269
Cdd:PRK06749 153 VDLYEELHQDAKE-ITGIETGYTSLNKMTCGLQEGDFVVLGARPSMGKTAFALNVGLHAAK-SGAAVGLFSLEMSSKQLL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 270 MRSLASLSRVDQTKIRTGQ--LDDEDWARISGTMGiLLEKRNIYIDDSSGLTPTEVRSRARRIAREHGGIG-LIMIDYLQ 346
Cdd:PRK06749 231 KRMASCVGEVSGGRLKNPKhrFAMEDWEKVSKAFA-EIGELPLEIYDNAGVTVQDIWMQTRKLKRKHGDKKiLIIVDYLQ 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 347 LMRV-PALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNSDLRESGSIEQDADLIMFIYRDEVYH 425
Cdd:PRK06749 310 LITGdPKHKGNRFQEISEISRKLKLLARELNVCVVALSQLSRSVESRQDKRPLLSDLRETGQIEQDADVIMLMYREDYYD 389
|
410 420 430
....*....|....*....|....*....|....*..
gi 16131878 426 ENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDN 462
Cdd:PRK06749 390 KETMQKEMTEIHVAKHRNGPVGSFKLRFLKEFGRFVE 426
|
|
| DnaB |
pfam00772 |
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at ... |
26-128 |
5.24e-43 |
|
DnaB-like helicase N terminal domain; The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This N-terminal domain is required both for interaction with other proteins in the primosome and for DnaB helicase activity.
Pssm-ID: 395624 [Multi-domain] Cd Length: 103 Bit Score: 147.38 E-value: 5.24e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 26 VPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGGFAY 105
Cdd:pfam00772 1 VPPHNIEAEQAVLGALLLDPEAIDEVADILKPEDFYDPAHRLIFEAILDLYDKGEPIDPVTVAEELEKKGKLEDVGGIAY 80
|
90 100
....*....|....*....|...
gi 16131878 106 LAELSKNTPSAANISAYADIVRE 128
Cdd:pfam00772 81 LAELAANVPSAANIEYYARIVKE 103
|
|
| PRK07773 |
PRK07773 |
replicative DNA helicase; Validated |
407-464 |
3.28e-19 |
|
replicative DNA helicase; Validated
Pssm-ID: 236093 [Multi-domain] Cd Length: 886 Bit Score: 90.96 E-value: 3.28e-19
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 16131878 407 SIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYA 464
Cdd:PRK07773 827 SIEQDADVVILLYRPDYYDRDDPRGGEAEFIVAKHRNGPTGTVTLAFQLHLSRFANLA 884
|
|
| RecA-like_Gp4D_helicase |
cd19483 |
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the ... |
227-448 |
1.57e-17 |
|
RecA-like domain of Escherichia coli bacteriophage T7 Gp4D helicase; This family includes the RecA-like domain of the Gp4D fragment of the Gene4 helicase-primase (Gp4) from bacteriophage T7. Gp4D (residues 241-566) is the minimal fragment of the Gp4 that forms hexameric rings, it contains the helicase domain and the linker connecting the helicase and primase domains. Helicases are ring-shaped oligomeric enzymes that unwind DNA at the replication fork; they couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. This family belongs to the RecA-like NTPase superfamily which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410891 [Multi-domain] Cd Length: 231 Bit Score: 81.46 E-value: 1.57e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 227 IIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGqlDDEDWARISGTMGILLE 306
Cdd:cd19483 1 VTIGAGSGIGKSTIVRELAYHLITEHGEKVGIISLEESVEETAKGLAGKHLGKPEPLELPR--DDITEEEEDDAFDNELG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 307 KRNIYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQ-LMRVPALSDNRTlEIAEISRSLKALAKELNVPVVALSQL 385
Cdd:cd19483 79 SGRFFLYDHFGSLDWDNLKEKIRYMVKVLGCKVIVLDHLTiLVSGLDSSDERK-ELDEIMTELAALVKELGVTIILVSHL 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 16131878 386 NRSlEQRAD----KRPVNSDLRESGSIEQDADLIMFIYRDEvYHENSDLKGIAEIIIGKQRN----GPIGT 448
Cdd:cd19483 158 RRP-GGGKGheegGEVSESDLRGSSAIAQLSDYVIGLERNK-QADDPVERNTTRVRVLKNRFtgetGIAGT 226
|
|
| 41 |
PHA02542 |
41 helicase; Provisional |
214-422 |
1.48e-12 |
|
41 helicase; Provisional
Pssm-ID: 222864 [Multi-domain] Cd Length: 473 Bit Score: 69.32 E-value: 1.48e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 214 LNKKT-AGLQPSDLIIVAARPSMGKTTFAMNLVEnAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIrtgqlDDE 292
Cdd:PHA02542 179 LNKITkGGAERKTLNVLLAGVNVGKSLGLCSLAA-DYLQQGYNVLYISMEMAEEVIAKRIDANLLDVSLDDI-----DDL 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 293 DWARISGTMGILLEKRN----IYIDDSSGLTPTEVRSRARRIAREHGGI-GLIMIDYLQLM---RVPALSDNRTLEIAEI 364
Cdd:PHA02542 253 SKAEYKAKMEKLRSKTQgkliIKQYPTGGAHAGHFRALLNELKLKKNFKpDVIIVDYLGICassRLRVSSENSYTYVKAI 332
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 16131878 365 SRSLKALAKELNVPVVALSQLNRSLEQRADkrPVNSDLRESGSIEQDADLIMFIYRDE 422
Cdd:PHA02542 333 AEELRGLAVEHDVVVWTAAQTTRSGWDSSD--VDMSDTAESAGLPATADFMLAVIETE 388
|
|
| PRK05973 |
PRK05973 |
replicative DNA helicase; Provisional |
221-403 |
1.13e-09 |
|
replicative DNA helicase; Provisional
Pssm-ID: 168322 [Multi-domain] Cd Length: 237 Bit Score: 58.51 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 221 LQPSDLIIVAARPSMGKTTFAMNLVEnAAMLQDKPVLIFSLEMPSEQIMMRsLASLSrVDQTKIRTG-QLDDEDwaRISG 299
Cdd:PRK05973 61 LKPGDLVLLGARPGHGKTLLGLELAV-EAMKSGRTGVFFTLEYTEQDVRDR-LRALG-ADRAQFADLfEFDTSD--AICA 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 300 TmgillekrniYIddssgltptevrsrARRIAREHGGiGLIMIDYLQLM----RVPALSDNrtleiaeiSRSLKALAKEL 375
Cdd:PRK05973 136 D----------YI--------------IARLASAPRG-TLVVIDYLQLLdqrrEKPDLSVQ--------VRALKSFARER 182
|
170 180
....*....|....*....|....*...
gi 16131878 376 NVPVVALSQLNRSLEQRADKRPVNSDLR 403
Cdd:PRK05973 183 GLIIVFISQIDRSFDPSAKPLPDIRDVR 210
|
|
| AAA_25 |
pfam13481 |
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins. |
221-386 |
2.78e-08 |
|
AAA domain; This AAA domain is found in a wide variety of presumed DNA repair proteins.
Pssm-ID: 463892 [Multi-domain] Cd Length: 193 Bit Score: 53.54 E-value: 2.78e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 221 LQPSDLIIVAARPSMGKTTFAMNLVenAAMLQDKP------------VLIFSLEMPSEQIMMRSLASLSRVDqtkirtgq 288
Cdd:pfam13481 30 LPAGGLGLLAGAPGTGKTTLALDLA--AAVATGKPwlggprvpeqgkVLYVSAEGPADELRRRLRAAGADLD-------- 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 289 lDDEDWARISGTMGILLekrniYIDDSSGLTPTEVRSRARRIAREHGGIGLIMIDYLQlmRVPALSDNRTLEIAEISRSL 368
Cdd:pfam13481 100 -LPARLLFLSLVESLPL-----FFLDRGGPLLDADVDALEAALEEVEDPDLVVIDPLA--RALGGDENSNSDVGRLVKAL 171
|
170
....*....|....*...
gi 16131878 369 KALAKELNVPVVALSQLN 386
Cdd:pfam13481 172 DRLARRTGATVLLVHHVG 189
|
|
| RAD55 |
COG0467 |
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms]; |
220-423 |
1.27e-06 |
|
RecA-superfamily ATPase, KaiC/GvpD/RAD55 family [Signal transduction mechanisms];
Pssm-ID: 440235 [Multi-domain] Cd Length: 221 Bit Score: 49.14 E-value: 1.27e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 220 GLQPSDLIIVAARPSMGKTTFAMNLVENAAmLQDKPVLIFSLEMPSEQImMRSLASLSrvdqtkirtgqLDDEDwarisg 299
Cdd:COG0467 16 GLPRGSSTLLSGPPGTGKTTLALQFLAEGL-RRGEKGLYVSFEESPEQL-LRRAESLG-----------LDLEE------ 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 300 tmgiLLEKRNIYIDDSS----GLTPTEVRSRARRIAREHgGIGLIMID----YLQLMRVPAlsdnrtlEIAEISRSLKAL 371
Cdd:COG0467 77 ----YIESGLLRIIDLSpeelGLDLEELLARLREAVEEF-GAKRVVIDslsgLLLALPDPE-------RLREFLHRLLRY 144
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 16131878 372 AKELNVPVVALSQLnrsleqradkrPVNSDLRESGSIEQDADLIMFIYRDEV 423
Cdd:COG0467 145 LKKRGVTTLLTSET-----------GGLEDEATEGGLSYLADGVILLRYVEL 185
|
|
| KaiC-like |
cd01124 |
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. ... |
207-445 |
2.60e-06 |
|
Circadian Clock Protein KaiC; KaiC is a circadian clock protein, most studied in cyanobacteria. KaiC, an autokinase, autophosphatase, and ATPase, is part of the core oscillator, composed of three proteins: KaiA, KaiB, and KaiC. The circadian oscillation is regulated via KaiC phosphorylation.
Pssm-ID: 410869 [Multi-domain] Cd Length: 222 Bit Score: 48.41 E-value: 2.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 207 VNTGYDDLNKKTAGLQPSD-LIIVAARPSMGKTTFAMNLVENAAMLqDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIR 285
Cdd:cd01124 1 VKTGIPGLDELLGGGIPKGsVTLLTGGPGTGKTLFGLQFLYAGAKN-GEPGLFFTFEESPERLLRNAKSFGWDFDEMEDE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 286 tGQLDDEDwarisgtmgillekrnIYIDDSSGLTPTEVRSRARRIAREHgGIGLIMIDYLQLMRVPALSDNRtleIAEIS 365
Cdd:cd01124 80 -GKLIIVD----------------APPTEAGRFSLDELLSRILSIIKSF-KAKRVVIDSLSGLRRAKEDQMR---ARRIV 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 366 RSLKALAKELNVPVVALSQLNRSLeqradkrpvNSDLRESGSIEQDADLIMFIYRDEvyhENSDLKGIAEIIigKQRNGP 445
Cdd:cd01124 139 IALLNELRAAGVTTIFTSEMRSFL---------SSESAGGGDVSFIVDGVILLRYVE---IEGELRRTIRVL--KMRGTG 204
|
|
| RecA-like_superfamily |
cd01120 |
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ... |
227-409 |
6.47e-06 |
|
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.
Pssm-ID: 410865 [Multi-domain] Cd Length: 119 Bit Score: 45.19 E-value: 6.47e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 227 IIVAARPSMGKTTFAMNLVENAAmLQDKPVLIFSLempseqimmrslasLSRVDqtkirtgqlddedwarisgtmgille 306
Cdd:cd01120 1 ILITGPPGSGKTTLLLQFAEQAL-LSDEPVIFISF--------------LDTIL-------------------------- 39
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 307 krniyiddssgltptevrsRARRIAREHGGIGLIMIDYLQLMrVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLN 386
Cdd:cd01120 40 -------------------EAIEDLIEEKKLDIIIIDSLSSL-ARASQGDRSSELLEDLAKLLRAARNTGITVIATIHSD 99
|
170 180
....*....|....*....|...
gi 16131878 387 RSLEqraDKRPVNSDLRESGSIE 409
Cdd:cd01120 100 KFDI---DRGGSSNDERLLKSLR 119
|
|
| Rad51B |
cd19493 |
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair ... |
236-384 |
2.47e-04 |
|
RAD51B recombinase; RAD51B recombinase, a RAD51 paralog, plays an important role in DNA repair by homologous recombination (HR). HR is an important error-free repair mechanism for chromosomal double-strand break (DSB) which otherwise leads to cell cycle arrest and death. RAD51B, together with the other RAD51 paralogs, RAD51C, RAD51D, XRCC3, and XRCC2, helps recruit RAD51 to the break site.
Pssm-ID: 410901 [Multi-domain] Cd Length: 222 Bit Score: 42.31 E-value: 2.47e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 236 GKTTFAMNLVENAAMLQDKP-----VLIFSLEmpSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISgtmgillekRNI 310
Cdd:cd19493 23 GKTQFALTLASSAAMPARKGgldggVLYIDTE--SKFSAERLAEIAEARFPEAFSGFMEENERAEEML---------KRV 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 311 YIddSSGLTPTEVRSRARRIaREH---GGIGLIMIDYLQ-LMR--VPALSDN---RTLEIAEISRSLKALAKELNVPVVA 381
Cdd:cd19493 92 AV--VRVTTLAQLLERLPNL-EEHilsSGVRLVVIDSIAaLVRreFGGSDGEvteRHNALAREASSLKRLAEEFRIAVLV 168
|
...
gi 16131878 382 LSQ 384
Cdd:cd19493 169 TNQ 171
|
|
| AAA_33 |
pfam13671 |
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ... |
226-335 |
2.70e-03 |
|
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.
Pssm-ID: 463952 [Multi-domain] Cd Length: 143 Bit Score: 38.06 E-value: 2.70e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16131878 226 LIIVAARPSMGKTTFAMNLVENAAMlqdkpVLIfslempSEQIMMRSLASLSRVDQTkiRTGQLDDEDWARISGTMGILL 305
Cdd:pfam13671 1 LILLVGLPGSGKSTLARRLLEELGA-----VRL------SSDDERKRLFGEGRPSIS--YYTDATDRTYERLHELARIAL 67
|
90 100 110
....*....|....*....|....*....|
gi 16131878 306 EKRNIYIDDSSGLTPTEvRSRARRIAREHG 335
Cdd:pfam13671 68 RAGRPVILDATNLRRDE-RARLLALAREYG 96
|
|
| |
