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Conserved domains on  [gi|16766937|ref|NP_462552|]
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putative acetyltransferase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

Protein Classification

GNAT family protein( domain architecture ID 106742)

GNAT (Gcn5-related N-acetyltransferase) family protein similar to N-acetyltransferases that catalyze the transfer of an acetyl group from acetyl-CoA to a substrate

PubMed:  15581578

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PhnO super family cl42766
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 85-156 2.04e-09

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


The actual alignment was detected with superfamily member COG0454:

Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 52.75  E-value: 2.04e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16766937  85 PVIILARLAVDLSFHGKGLGADLLHDAVlrcyRVAENIGVRAIMVHALT--EEAKNFYIHHGFKSSQTQQRTLF 156
Cdd:COG0454  57 KVLELKRLYVLPEYRGKGIGKALLEALL----EWARERGCTALELDTLDgnPAAIRFYERLGFKEIERYVAYVG 126
 
Name Accession Description Interval E-value
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 85-156 2.04e-09

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 52.75  E-value: 2.04e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16766937  85 PVIILARLAVDLSFHGKGLGADLLHDAVlrcyRVAENIGVRAIMVHALT--EEAKNFYIHHGFKSSQTQQRTLF 156
Cdd:COG0454  57 KVLELKRLYVLPEYRGKGIGKALLEALL----EWARERGCTALELDTLDgnPAAIRFYERLGFKEIERYVAYVG 126
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 89-146 8.76e-08

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 48.04  E-value: 8.76e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 16766937    89 LARLAVDLSFHGKGLGADLLHDAVLRCyrVAENIGVRAIMVHAlTEEAKNFYIHHGFK 146
Cdd:pfam13673  54 ISLLFVDPDYQGQGIGKALLEAVEDYA--EKDGIKLSELTVNA-SPYAVPFYEKLGFR 108
 
Name Accession Description Interval E-value
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 85-156 2.04e-09

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 52.75  E-value: 2.04e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 16766937  85 PVIILARLAVDLSFHGKGLGADLLHDAVlrcyRVAENIGVRAIMVHALT--EEAKNFYIHHGFKSSQTQQRTLF 156
Cdd:COG0454  57 KVLELKRLYVLPEYRGKGIGKALLEALL----EWARERGCTALELDTLDgnPAAIRFYERLGFKEIERYVAYVG 126
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
38-156 3.97e-08

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 49.31  E-value: 3.97e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766937  38 QALGAARTFVVCKKDtkQVAGFYSLAtgsvnhteatgnlRRNMPDPIPVIILARLAVDLSFHGKGLGADLLHDAVlrcyR 117
Cdd:COG3153  34 EDPAAGLSLVAEDDG--EIVGHVALS-------------PVDIDGEGPALLLGPLAVDPEYRGQGIGRALMRAAL----E 94

                        90       100       110
                ....*....|....*....|....*....|....*....
gi 16766937 118 VAENIGVRAIMVHAlTEEAKNFYIHHGFKSSQTQQRTLF 156
Cdd:COG3153  95 AARERGARAVVLLG-DPSLLPFYERFGFRPAGELGLTLG 132
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 89-146 8.76e-08

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 48.04  E-value: 8.76e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 16766937    89 LARLAVDLSFHGKGLGADLLHDAVLRCyrVAENIGVRAIMVHAlTEEAKNFYIHHGFK 146
Cdd:pfam13673  54 ISLLFVDPDYQGQGIGKALLEAVEDYA--EKDGIKLSELTVNA-SPYAVPFYEKLGFR 108
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
81-146 1.25e-06

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 45.18  E-value: 1.25e-06
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 16766937  81 PDPIPVIILARLAVDLSFHGKGLGADLLHDAVlrcyRVAENIGVRAIMVHAlTEEAKNFYIHHGFK 146
Cdd:COG2153  53 PPGDGEAKIGRVAVLPEYRGQGLGRALMEAAI----EEARERGARRIVLSA-QAHAVGFYEKLGFV 113
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 89-146 3.14e-05

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 41.52  E-value: 3.14e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 16766937  89 LARLAVDLSFHGKGLGADLLHdavlRCYRVAENIGVRAIMVHAlTEEAKNFYIHHGFK 146
Cdd:COG1246  55 LRSLAVHPDYRGRGIGRRLLE----ALLAEARELGLKRLFLLT-TSAAIHFYEKLGFE 107
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 89-146 4.23e-05

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 40.02  E-value: 4.23e-05
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766937  89 LARLAVDLSFHGKGLGADLLHDAVlrcyRVAENIGVRAIMVHALT--EEAKNFYIHHGFK 146
Cdd:COG0456  16 IEDLAVDPEYRGRGIGRALLEAAL----ERARERGARRLRLEVREdnEAAIALYEKLGFE 71
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 74-146 4.99e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 39.75  E-value: 4.99e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 16766937    74 GNLRRNMPDPIPVIILARLAVDLSFHGKGLGADLLHdavlRCYRVAENIGVRAIMVHAlTEEAKNFYIHHGFK 146
Cdd:pfam13508  16 GFAALLPLDDEGALAELRLAVHPEYRGQGIGRALLE----AAEAAAKEGGIKLLELET-TNRAAAFYEKLGFE 83
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 35-145 1.30e-04

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 39.42  E-value: 1.30e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 16766937    35 LKNQALGAARTFVVCKKDTKqVAGFYSLatgsvnhteatgnlrRNMPDPIPVIILARLAVDLSFHGKGLGADLLHDAVlr 114
Cdd:pfam00583  24 LEDWDEDASEGFFVAEEDGE-LVGFASL---------------SIIDDEPPVGEIEGLAVAPEYRGKGIGTALLQALL-- 85

                          90       100       110
                  ....*....|....*....|....*....|...
gi 16766937   115 cyRVAENIGVRAIMVHALT--EEAKNFYIHHGF 145
Cdd:pfam00583  86 --EWARERGCERIFLEVAAdnLAAIALYEKLGF 116
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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