|
Name |
Accession |
Description |
Interval |
E-value |
| CNH |
smart00036 |
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2; |
965-1248 |
3.10e-84 |
|
Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2;
Pssm-ID: 214481 Cd Length: 302 Bit Score: 277.31 E-value: 3.10e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 965 NNLKIFKAYTIE-DWILFATQTGLFFTSIS-QPRNPMRIAGPNSVTSLEIMAEIKCVAMVANSSGQLAMIPLDSLIL--- 1039
Cdd:smart00036 1 NTAKWNHPITCDgKWLLVGTEEGLYVLNISdQPGTLEKLIGRRSVTQIWVLEENNVLLMISGKKPQLYSHPLSALVEkke 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 1040 AMQSTQPSIRPEILPEFEHVH-MIKYHQQNGQRFLLISDDTHLHVRKYNaTRDIFSQYAKF----------DVPEPISFI 1108
Cdd:smart00036 81 ALGSARLVIRKNVLTKIPDVKgCHLCAVVNGKRSLFLCVALQSSVVLLQ-WYNPLKKFKLFkskflfplisPVPVFVELV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 1109 ESAP--SGIIFACDT-FYYVALDHQtsSNVSARKLMSPNKNEF----PISAQMINQNEVLLAYQNQGIFVNLHG-EQSRN 1180
Cdd:smart00036 160 SSSFerPGICIGSDKgGGDVVQFHE--SLVSKEDLSLPFLSEEtslkPISVVQVPRDEVLLCYDEFGVFVNLYGkRRSRN 237
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17534555 1181 ETIEWEKMPMEFIYTSPFLYIVHDDSIEILEISETSDRTVLAERalfECVNAHVIGRQYEGVLISVSS 1248
Cdd:smart00036 238 PILHWEFMPESFAYHSPYLLAFHDNGIEIRSIKTGELLQELADR---ETRKIRLLGSSDRKILLSSSP 302
|
|
| CNH |
pfam00780 |
CNH domain; Domain found in NIK1-like kinase, mouse citron and yeast ROM1, ROM2. Unpublished ... |
976-1231 |
8.26e-72 |
|
CNH domain; Domain found in NIK1-like kinase, mouse citron and yeast ROM1, ROM2. Unpublished observations.
Pssm-ID: 459938 Cd Length: 261 Bit Score: 240.61 E-value: 8.26e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 976 EDWILFATQTGLFFTSISQPRNPMRIAGPNSVTSLEIMAEIKCVAMVANSSGQLAMIPLDSLILAMQSTQPSIRPEILPE 1055
Cdd:pfam00780 2 GQNLLLGTEEGLYVLNRSGPREPVRIIDKKRVTQLAVLEEFNLLLLLSGKDKRLYVYPLSALDSREENDRKDAAKNKLPE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 1056 FEHVHMIKYHQQNGQRFLLISDDTHLHVRKYNAT-RDIFSQYAKFDVPEPISFIESAPSGIIFACDTFYY-VALDHQTSS 1133
Cdd:pfam00780 82 TKGCHFFKVGRHSNGRFLVVAVKRTIKLLEWYEPlLDKFRKFKEFYLPSPPVSIELLKSKLCVGCAKGFEiVSLDSKATE 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 1134 NV-SARKLMSPNKNEFPISAQMINQNEVLLAYQNQGIFVNLHGEQSRNETIEWEKMPMEFIYTSPFLYIVHDDSIEILEI 1212
Cdd:pfam00780 162 SLlTSLLFANRQENLKPLAVVRLDRSEFLLCYNEFGVYVNLQGRRSRPWEIEWEGAPEAVAYLYPYLLAFHDNFIEIRDV 241
|
250
....*....|....*....
gi 17534555 1213 SETSDRTVLAERALFECVN 1231
Cdd:pfam00780 242 ETGELVQEIAGRKIRFLNS 260
|
|
| CRIK |
cd20814 |
protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) ... |
754-811 |
1.23e-20 |
|
protein kinase C conserved region 1 (C1 domain) found in citron Rho-interacting kinase (CRIK) and similar proteins; CRIK, also called serine/threonine-protein kinase 21, is an effector of the small GTPase Rho. It plays an important function during cytokinesis and affects its contractile process. CRIK-deficient mice show severe ataxia and epilepsy as a result of abnormal cytokinesis and massive apoptosis in neuronal precursors. A Down syndrome critical region protein TTC3 interacts with CRIK and inhibits CRIK-dependent neuronal differentiation and neurite extension. CRIK contains a catalytic domain, a central coiled-coil domain, and a C-terminal region containing a Rho-binding domain (RBD), a zinc finger (C1 domain), and a pleckstrin homology (PH) domain, in addition to other motifs. This model corresponds to C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410364 Cd Length: 56 Bit Score: 86.53 E-value: 1.23e-20
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 17534555 754 HDIPHKWKAFRHVGvlSMKCSLCFVGISAFAKAKKCSHCDVHVHASCAPRVNNTCGMP 811
Cdd:cd20814 1 HNIPHRFTTGLNMR--ATKCAVCLDGVPFGRQASKCSECGIVCHPKCSSSLPNTCGLP 56
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
49-717 |
2.92e-19 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 94.35 E-value: 2.92e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 49 KRVLDAENIIQDLRSERDALHETLVDKAGLNESVIIEQSK-RVSTQETRIYRRDVNLLEDDLKHHQSQIRILQNKCSTLE 127
Cdd:TIGR02168 222 LRELELALLVLRLEELREELEELQEELKEAEEELEELTAElQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLE 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 128 MEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELTSFRMEYVtklsEANREKKAL 207
Cdd:TIGR02168 302 QQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELE----ELESRLEEL 377
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 208 EEKLEKYKNDMKENDRKSLELNKEQvttQNVLSEVRQLSAHFEFLTPVRKNASKIRELDEYHQLSAKV--IEESMNDLKI 285
Cdd:TIGR02168 378 EEQLETLRSKVAQLELQIASLNNEI---ERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELeeLEEELEELQE 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 286 KNETLTKELSDKTELVKMKNEELEDLRQtTTASLGDSEQATKYLHEENMKLTRQKAdircELLEARRKVEGFD------- 358
Cdd:TIGR02168 455 ELERLEEALEELREELEEAEQALDAAER-ELAQLQARLDSLERLQENLEGFSEGVK----ALLKNQSGLSGILgvlseli 529
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 359 KLKQELEKERDDALAD------VQKIREVKRNVERELQSLTS------LMAERDEQIE----ELKTKMFSFEMIKKDHES 422
Cdd:TIGR02168 530 SVDEGYEAAIEAALGGrlqavvVENLNAAKKAIAFLKQNELGrvtflpLDSIKGTEIQgndrEILKNIEGFLGVAKDLVK 609
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 423 AKNELSRT--------------QEKLDQMGK------------HLIMADqQCSTFKSLK-ESAEGSRRRAIE----QCNE 471
Cdd:TIGR02168 610 FDPKLRKAlsyllggvlvvddlDNALELAKKlrpgyrivtldgDLVRPG-GVITGGSAKtNSSILERRREIEeleeKIEE 688
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 472 MVVRIRDLQTSLESQRK----VEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSRLAEKTKGKEDADHLRLTLSQ 547
Cdd:TIGR02168 689 LEEKIAELEKALAELRKeleeLEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEE 768
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 548 RDSELRSAKKTIQEVKADNQKVqlmlvevrqhQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKED 627
Cdd:TIGR02168 769 RLEEAEEELAEAEAEIEELEAQ----------IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATER 838
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 628 KLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQPKLGRRSTLLSTVSEMDTSVYMREAEEVRALEEQRQALMSNLA 707
Cdd:TIGR02168 839 RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELE 918
|
730
....*....|
gi 17534555 708 EKRRQLVDSK 717
Cdd:TIGR02168 919 ELREKLAQLE 928
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
36-651 |
4.40e-19 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 93.59 E-value: 4.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 36 VIDLNNESHEDLKKRVLDAENIIQDLRSERDALHETLvDKAGLNESVIIEQSKRVSTQETRIyrrdvnlleDDLKHHQSQ 115
Cdd:PRK03918 170 VIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVL-REINEISSELPELREELEKLEKEV---------KELEELKEE 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 116 IRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLeKELSAKAndifmvtkdlhDKNEELTSFRMEYVT 195
Cdd:PRK03918 240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKEL-KELKEKA-----------EEYIKLSEFYEEYLD 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 196 KLSEANREKKALEEKLEKYKNDMKENDRKSLELNKeqvtTQNVLSEVRQlsahfefltpvrknasKIRELDEYHQL--SA 273
Cdd:PRK03918 308 ELREIEKRLSRLEEEINGIEERIKELEEKEERLEE----LKKKLKELEK----------------RLEELEERHELyeEA 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 274 KVIEESMNDLKIKNETLTKE-LSDKTELVKMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLtrQKADIRC-----EL 347
Cdd:PRK03918 368 KAKKEELERLKKRLTGLTPEkLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEEL--KKAKGKCpvcgrEL 445
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 348 LEARRK--VEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERD--EQIEELKTKMFSFEmiKKDHESA 423
Cdd:PRK03918 446 TEEHRKelLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKElaEQLKELEEKLKKYN--LEELEKK 523
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 424 KNELSRTQEKLDQMGKHLimadqqcstfKSLKESaegsrrraIEQCNEMVVRIRDLQTSLesqRKVEQEVEMLKAENSRQ 503
Cdd:PRK03918 524 AEEYEKLKEKLIKLKGEI----------KSLKKE--------LEKLEELKKKLAELEKKL---DELEEELAELLKELEEL 582
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 504 A-KKIEFMKEEIQEVHLDYR---------QELSRLAEKTKG-KEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKvqlm 572
Cdd:PRK03918 583 GfESVEELEERLKELEPFYNeylelkdaeKELEREEKELKKlEEELDKAFEELAETEKRLEELRKELEELEKKYSE---- 658
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 573 lvevrQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERL-----ERESATKE-DKLDKLEEELQEKKQQIAES 646
Cdd:PRK03918 659 -----EEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLkeeleEREKAKKElEKLEKALERVEELREKVKKY 733
|
....*
gi 17534555 647 KELVT 651
Cdd:PRK03918 734 KALLK 738
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
134-746 |
6.92e-16 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 83.57 E-value: 6.92e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 134 QETIQRAQDDKKETETELESSRS------RLHVLEKELSAKanDIFMVTKDLHDKNEELTSFRM---EYVTKLSEANREK 204
Cdd:TIGR02168 185 RENLDRLEDILNELERQLKSLERqaekaeRYKELKAELREL--ELALLVLRLEELREELEELQEelkEAEEELEELTAEL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 205 KALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEV-RQLSAHFEFLTPVRKNASKIRELDEYHQLSAKVIEESMNDL 283
Cdd:TIGR02168 263 QELEEKLEELRLEVSELEEEIEELQKELYALANEISRLeQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAEL 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 284 KIKNETLTKELSDKTELVKMKNEELEDLRQTttasLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKLKQE 363
Cdd:TIGR02168 343 EEKLEELKEELESLEAELEELEAELEELESR----LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER 418
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 364 LEKERDDALADVQ--KIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMgkhl 441
Cdd:TIGR02168 419 LQQEIEELLKKLEeaELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL---- 494
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 442 imadqqcstfKSLKESAEGSRR--RAIEQCNEMVVRIRD-LQTSLESQRKVEQEVE--------MLKAENSRQAKK-IEF 509
Cdd:TIGR02168 495 ----------ERLQENLEGFSEgvKALLKNQSGLSGILGvLSELISVDEGYEAAIEaalggrlqAVVVENLNAAKKaIAF 564
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 510 MKE-----------------EIQEVHLDYRQELS-------------------------------------RLAEK---- 531
Cdd:TIGR02168 565 LKQnelgrvtflpldsikgtEIQGNDREILKNIEgflgvakdlvkfdpklrkalsyllggvlvvddldnalELAKKlrpg 644
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 532 -----------------TKGKEDADHLRLtlsQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGM 594
Cdd:TIGR02168 645 yrivtldgdlvrpggviTGGSAKTNSSIL---ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKEL 721
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 595 ADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELvtyLHSQIDAKQTKQPKLGRRSTLL 674
Cdd:TIGR02168 722 EELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE---LAEAEAEIEELEAQIEQLKEEL 798
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17534555 675 STVSEMDTSV---YMREAEEVRALEEQRQALMSNLAEKRRQLVDSKKsQSTANTTIVTTTTTEISKSSQSASELS 746
Cdd:TIGR02168 799 KALREALDELraeLTLLNEEAANLRERLESLERRIAATERRLEDLEE-QIEELSEDIESLAAEIEELEELIEELE 872
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
125-718 |
1.48e-15 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 82.03 E-value: 1.48e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 125 TLEMEKQTLQETIQRA---QDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLhdknEELTSFRmeyvTKLSEAN 201
Cdd:PRK03918 173 EIKRRIERLEKFIKRTeniEELIKEKEKELEEVLREINEISSELPELREELEKLEKEV----KELEELK----EEIEELE 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 202 REKKALEEKLEKYKNDMKENDRKSLELNKEqvttqnvLSEVRQLSAHFEFLTPVRKNASKIREL-DEYHQLSAKvIEESM 280
Cdd:PRK03918 245 KELESLEGSKRKLEEKIRELEERIEELKKE-------IEELEEKVKELKELKEKAEEYIKLSEFyEEYLDELRE-IEKRL 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 281 NDLKIKNETLTKELSDKTElvkmKNEELEDLRqtttaslgdseqatKYLHEENMKLTRQKADIRcELLEARRKVEGFDKL 360
Cdd:PRK03918 317 SRLEEEINGIEERIKELEE----KEERLEELK--------------KKLKELEKRLEELEERHE-LYEEAKAKKEELERL 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 361 KQELE-KERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEmikkdheSAKNELSRTQEKLDQMGK 439
Cdd:PRK03918 378 KKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELK-------KAKGKCPVCGRELTEEHR 450
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 440 HLIMADQQCSTFKSLKESAEgsrrrAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMlkaensrqAKKIEFMKEEIQEVHL 519
Cdd:PRK03918 451 KELLEEYTAELKRIEKELKE-----IEEKERKLRKELRELEKVLKKESELIKLKEL--------AEQLKELEEKLKKYNL 517
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 520 DYRQELSRLAEKTKGKedadhlrltLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLR-------K 592
Cdd:PRK03918 518 EELEKKAEEYEKLKEK---------LIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEelgfesvE 588
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 593 GMADALAKIEEYKRSWQNSQETCERLEREsatkEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTK-----QPKL 667
Cdd:PRK03918 589 ELEERLKELEPFYNEYLELKDAEKELERE----EKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKyseeeYEEL 664
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|.
gi 17534555 668 GRRSTLLStvsemdtSVYMREAEEVRALEEQRQALMSNLAEKRRQLVDSKK 718
Cdd:PRK03918 665 REEYLELS-------RELAGLRAELEELEKRREEIKKTLEKLKEELEEREK 708
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
135-744 |
1.68e-15 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 82.50 E-value: 1.68e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 135 ETIQRAQDDKKeteteLESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEEltsfRMEYVTKLSEANREKKAleEKLEKY 214
Cdd:PTZ00121 1167 EEARKAEDAKK-----AEAARKAEEVRKAEELRKAEDARKAEAARKAEEER----KAEEARKAEDAKKAEAV--KKAEEA 1235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 215 KNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEFLTPVRKNASKIRELDEYHQL-SAKVIEE--SMNDLKIKNETLT 291
Cdd:PTZ00121 1236 KKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAdEAKKAEEkkKADEAKKKAEEAK 1315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 292 K--ELSDKTELVKMKNEEL----EDLRQTTTASLGDSEQATKYLHEENMKL---------TRQKADIRCELLEARRKVEG 356
Cdd:PTZ00121 1316 KadEAKKKAEEAKKKADAAkkkaEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaekkkeeAKKKADAAKKKAEEKKKADE 1395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 357 FDKLKQELEKERDD---ALADVQKIREVKRNVE--RELQSLTSlMAERDEQIEELKTKmfSFEMIKKDHESAKNELSRTQ 431
Cdd:PTZ00121 1396 AKKKAEEDKKKADElkkAAAAKKKADEAKKKAEekKKADEAKK-KAEEAKKADEAKKK--AEEAKKAEEAKKKAEEAKKA 1472
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 432 EKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKVEqevEMLKAENSRQAKKIEFMK 511
Cdd:PTZ00121 1473 DEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAE---EAKKADEAKKAEEKKKAD 1549
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 512 EEIQEVHLDYRQELSRLAEKTKGKEDadhlRLTLSQRDSELRSA-KKTIQEVKADNQKVQLMLVEVRQHQEKileenvrl 590
Cdd:PTZ00121 1550 ELKKAEELKKAEEKKKAEEAKKAEED----KNMALRKAEEAKKAeEARIEEVMKLYEEEKKMKAEEAKKAEE-------- 1617
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 591 RKGMADALAKIEEYKRSwqnsQETCERLERESATKEDKLDKLEEELQEKKQQIA----ESKELVTYLHSQIDAKQTKQPK 666
Cdd:PTZ00121 1618 AKIKAEELKKAEEEKKK----VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAkkaeEDKKKAEEAKKAEEDEKKAAEA 1693
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 667 LGRRSTLLSTVSEM--DTSVYMREAEEVRALEEQRQALMSNLaeKRRQLVDSKKSQSTANTTIVTTTTTEISKSSQSASE 744
Cdd:PTZ00121 1694 LKKEAEEAKKAEELkkKEAEEKKKAEELKKAEEENKIKAEEA--KKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAE 1771
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
100-648 |
3.66e-15 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 80.83 E-value: 3.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 100 RDVNLLEDDLKHHQSQIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDL 179
Cdd:TIGR04523 103 SDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEK 182
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 180 HDKNEELTSFRMEY------VTKLSEANREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVRQLsahfefLT 253
Cdd:TIGR04523 183 LNIQKNIDKIKNKLlklellLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQ------LN 256
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 254 PVRKNASKIREldeyhQLSAKVIEESMNDLKIKNetLTKELSD-KTELVKMKNEELEDL--------------RQTTTAS 318
Cdd:TIGR04523 257 QLKDEQNKIKK-----QLSEKQKELEQNNKKIKE--LEKQLNQlKSEISDLNNQKEQDWnkelkselknqekkLEEIQNQ 329
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 319 LGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAE 398
Cdd:TIGR04523 330 ISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQ 409
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 399 RDEQIEELKTkmfSFEMIKKDHESAKNELSRTQEKLDQMGKhlimadqQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRD 478
Cdd:TIGR04523 410 KDEQIKKLQQ---EKELLEKEIERLKETIIKNNSEIKDLTN-------QDSVKELIIKNLDNTRESLETQLKVLSRSINK 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 479 LQTSLESQRK----VEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQ---ELSRLAEKTKGKED---ADHLRLTLSQR 548
Cdd:TIGR04523 480 IKQNLEQKQKelksKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKlesEKKEKESKISDLEDelnKDDFELKKENL 559
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 549 DSELRSAKKTIQEVKADNQKvqlMLVEVRQHQEKILE---ENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATK 625
Cdd:TIGR04523 560 EKEIDEKNKEIEELKQTQKS---LKKKQEEKQELIDQkekEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNI 636
|
570 580
....*....|....*....|...
gi 17534555 626 EDKLDKLEEELQEKKQQIAESKE 648
Cdd:TIGR04523 637 KSKKNKLKQEVKQIKETIKEIRN 659
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
45-553 |
4.34e-15 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 80.47 E-value: 4.34e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 45 EDLKKRVLDAENIIQDLRSERDALhetlVDKAGLNESVIIEQSKRVSTQETRI--YRRDVNLLEDDLKHHQSQIRILQNK 122
Cdd:PRK02224 275 EELAEEVRDLRERLEELEEERDDL----LAEAGLDDADAEAVEARREELEDRDeeLRDRLEECRVAAQAHNEEAESLRED 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 123 CSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLhdknEELTSFRMEYVTKLSEANR 202
Cdd:PRK02224 351 ADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDL----GNAEDFLEELREERDELRE 426
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 203 EKKALEEKLEKYKNDMKENdRKSLELNKEQVTTQNVlsevrqlsahfefltpvrKNASKIRELDEYHQLSAKvIEESMND 282
Cdd:PRK02224 427 REAELEATLRTARERVEEA-EALLEAGKCPECGQPV------------------EGSPHVETIEEDRERVEE-LEAELED 486
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 283 LKIKNETLTKELSDKTELVKMKnEELEDLRqtttaslgdseqatkylheENMKLTRQKADIRCELLEARR-KVEGFDKLK 361
Cdd:PRK02224 487 LEEEVEEVEERLERAEDLVEAE-DRIERLE-------------------ERREDLEELIAERRETIEEKReRAEELRERA 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 362 QELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIkkdhESAKNELSRTQEKLDQMGKhl 441
Cdd:PRK02224 547 AELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAI----ADAEDEIERLREKREALAE-- 620
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 442 iMADQQCSTFKSLKEsaegsRRRAIEQC--NEMVVRIR-DLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVH 518
Cdd:PRK02224 621 -LNDERRERLAEKRE-----RKRELEAEfdEARIEEAReDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELE 694
|
490 500 510
....*....|....*....|....*....|....*....
gi 17534555 519 lDYRQELSRLAEKTKGKED----ADHLRLTLSQRDSELR 553
Cdd:PRK02224 695 -ELRERREALENRVEALEAlydeAEELESMYGDLRAELR 732
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
48-682 |
8.00e-15 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 79.98 E-value: 8.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 48 KKRVLDAENIIQDLRsERDALHETLVDKAGLNESVIIEQSKRVSTQETRI--YRRDVNLLEDDLKHHQSQIRILQNKCST 125
Cdd:COG1196 221 ELKELEAELLLLKLR-ELEAELEELEAELEELEAELEELEAELAELEAELeeLRLELEELELELEEAQAEEYELLAELAR 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 126 LEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELTSFRmeyvTKLSEANREKK 205
Cdd:COG1196 300 LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE----EALLEAEAELA 375
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 206 ALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEfltpvRKNASKIRELDEYHQLSAKVIEESMNDLKI 285
Cdd:COG1196 376 EAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLE-----EELEELEEALAELEEEEEEEEEALEEAAEE 450
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 286 KNETLTKELSDKTELVKMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQ---KADIRCELLEARRKVEGFDKLKQ 362
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflEGVKAALLLAGLRGLAGAVAVLI 530
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 363 ELEKERDDALADVQKIREVKRNVERElqsltslmAERDEQIEELKTKMF---SFEMIKKDHESAKNELSRTQEKLDQMGK 439
Cdd:COG1196 531 GVEAAYEAALEAALAAALQNIVVEDD--------EVAAAAIEYLKAAKAgraTFLPLDKIRARAALAAALARGAIGAAVD 602
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 440 HLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVHL 519
Cdd:COG1196 603 LVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE 682
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 520 DYRQELSRLAEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENvrlrkgmADALA 599
Cdd:COG1196 683 ELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE-------EALEE 755
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 600 KIEEYKRSWQnsQETCERLEREsatkedkLDKL-------EEELQEKKQQIaeskelvTYLHSQI-DAKQTKQpklgrrs 671
Cdd:COG1196 756 LPEPPDLEEL--ERELERLERE-------IEALgpvnllaIEEYEELEERY-------DFLSEQReDLEEARE------- 812
|
650
....*....|.
gi 17534555 672 TLLSTVSEMDT 682
Cdd:COG1196 813 TLEEAIEEIDR 823
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
109-435 |
1.12e-14 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 79.33 E-value: 1.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 109 LKHHQSQIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTK---DLHDKNEE 185
Cdd:TIGR02168 679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEEriaQLSKELTE 758
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 186 LTSFRMEYVTKLSEANREKKA-------LEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEfltpvRKN 258
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEaeaeieeLEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLE-----RRI 833
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 259 ASKIRELDEYHQLSAKV------IEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLR---QTTTASLGDSEQATKYL 329
Cdd:TIGR02168 834 AATERRLEDLEEQIEELsediesLAAEIEELEELIEELESELEALLNERASLEEALALLRselEELSEELRELESKRSEL 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 330 HEENMKLTRQKADIRCELLEARRKVEGF-DKLKQELEKERDDALADVQKIREVKRNVERELQSLTS---------LMAEr 399
Cdd:TIGR02168 914 RRELEELREKLAQLELRLEGLEVRIDNLqERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENkikelgpvnLAAI- 992
|
330 340 350
....*....|....*....|....*....|....*.
gi 17534555 400 dEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLD 435
Cdd:TIGR02168 993 -EEYEELKERYDFLTAQKEDLTEAKETLEEAIEEID 1027
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
132-713 |
2.42e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 78.16 E-value: 2.42e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 132 TLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKandifmVTKDLHDKneeltsfrmeyvtkLSEANREKKALEEKL 211
Cdd:PRK02224 163 KLEEYRERASDARLGVERVLSDQRGSLDQLKAQIEEK------EEKDLHER--------------LNGLESELAELDEEI 222
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 212 EKYkndmkendrkslELNKEQ-VTTQNVLSEVrqLSAHFEFLTPVRKNASKIRELDEyhqlsakVIEESMNdlkiKNETL 290
Cdd:PRK02224 223 ERY------------EEQREQaRETRDEADEV--LEEHEERREELETLEAEIEDLRE-------TIAETER----EREEL 277
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 291 TKELSDKTELVKMKNEELEDLRqtTTASLGDSEQATKYLHEENmkLTRQKADIRCELLEARRKVEGFDKLKQELEKERDD 370
Cdd:PRK02224 278 AEEVRDLRERLEELEEERDDLL--AEAGLDDADAEAVEARREE--LEDRDEELRDRLEECRVAAQAHNEEAESLREDADD 353
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 371 ALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMfsfemikkdhESAKNELSRTQEKLdqmgkhlimadqqcst 450
Cdd:PRK02224 354 LEERAEELREEAAELESELEEAREAVEDRREEIEELEEEI----------EELRERFGDAPVDL---------------- 407
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 451 fkslkESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSRLAe 530
Cdd:PRK02224 408 -----GNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRERVEELE- 481
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 531 ktkgkEDADHLRLTLSQRDSELRSAKKtiqevkadnqkvqlmLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQN 610
Cdd:PRK02224 482 -----AELEDLEEEVEEVEERLERAED---------------LVEAEDRIERLEERREDLEELIAERRETIEEKRERAEE 541
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 611 SQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAkqtkqpkLGRRSTLLSTVSEM-DTSVYMREA 689
Cdd:PRK02224 542 LRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIES-------LERIRTLLAAIADAeDEIERLREK 614
|
570 580
....*....|....*....|....*
gi 17534555 690 EEVRA-LEEQRQALMSNLAEKRRQL 713
Cdd:PRK02224 615 REALAeLNDERRERLAEKRERKREL 639
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
198-720 |
7.05e-14 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 77.10 E-value: 7.05e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 198 SEANREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVlSEVRQlsahfefltpvRKNASKIRELDEYHQLSAKVIE 277
Cdd:PTZ00121 1090 DEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKA-EEARK-----------AEDARKAEEARKAEDAKRVEIA 1157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 278 ESMNDLKIKNETLTKELSDKTELVKMKNE--ELEDLRQTTTASlgDSEQATKYLHEENMKLTRQKADIRceLLEARRKVE 355
Cdd:PTZ00121 1158 RKAEDARKAEEARKAEDAKKAEAARKAEEvrKAEELRKAEDAR--KAEAARKAEEERKAEEARKAEDAK--KAEAVKKAE 1233
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 356 GFDKLKQELEK-ERDDALADVQKIREVKRNVERELQSltSLMAERDEQIEELKTKmfsfEMIKKDHESAKNELSRTQEKL 434
Cdd:PTZ00121 1234 EAKKDAEEAKKaEEERNNEEIRKFEEARMAHFARRQA--AIKAEEARKADELKKA----EEKKKADEAKKAEEKKKADEA 1307
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 435 DQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEI 514
Cdd:PTZ00121 1308 KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKA 1387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 515 QEVHldYRQELSRLAEKTKGKedADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMlvEVRQHQEkiLEENVRLRKGM 594
Cdd:PTZ00121 1388 EEKK--KADEAKKKAEEDKKK--ADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAE--EAKKADE--AKKKAEEAKKA 1459
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 595 ADALAKIEEYKRSWQNSQETcerlerESATKEDKLDKLEEELQEKKQQIAESKElvtylhSQIDAKQTKQPKLGRRSTLL 674
Cdd:PTZ00121 1460 EEAKKKAEEAKKADEAKKKA------EEAKKADEAKKKAEEAKKKADEAKKAAE------AKKKADEAKKAEEAKKADEA 1527
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 17534555 675 STVSEMDTSVYMREAEEVRALEEQRQALMSNLAEKRRQLVDSKKSQ 720
Cdd:PTZ00121 1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAE 1573
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
129-662 |
7.26e-14 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 76.62 E-value: 7.26e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 129 EKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSakandifmvtkDLHDKNEELTSfrmeyVTKLSEANREkkALE 208
Cdd:PRK02224 252 ELETLEAEIEDLRETIAETEREREELAEEVRDLRERLE-----------ELEEERDDLLA-----EAGLDDADAE--AVE 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 209 EKLEkykndmkendrkslELNKEQVTTQNVLSEVR-QLSAHFEFLTPVRKNASKIRELDEYHQLSAKVIEESMNDLKikn 287
Cdd:PRK02224 314 ARRE--------------ELEDRDEELRDRLEECRvAAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAR--- 376
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 288 ETLTKELSDKTELvkmkNEELEDLRQT---TTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKLK--- 361
Cdd:PRK02224 377 EAVEDRREEIEEL----EEEIEELRERfgdAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLeag 452
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 362 ------QELE-KERDDALADVqkiREVKRNVERELQSLTSLMAERDEQIEELKtkmfsfemikkDHESAKNELSRTQEKL 434
Cdd:PRK02224 453 kcpecgQPVEgSPHVETIEED---RERVEELEAELEDLEEEVEEVEERLERAE-----------DLVEAEDRIERLEERR 518
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 435 DQMGKHLimaDQQCSTFKSLKESAEGSRRRAIEqcnemvvrirdLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEI 514
Cdd:PRK02224 519 EDLEELI---AERRETIEEKRERAEELRERAAE-----------LEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAEL 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 515 QEVhldyRQELSRLAEKTKGKEDADhlrltlsQRDSELRSAKKTIQEVKadnqkvqlmlvevRQHQEKILEENVRLRKgM 594
Cdd:PRK02224 585 KER----IESLERIRTLLAAIADAE-------DEIERLREKREALAELN-------------DERRERLAEKRERKRE-L 639
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 595 ADAL--AKIEEYKRSWQNSQETCERLERESATKEDKLDKLE-------------EELQEKKQQIAESKELVTYLHSQIDA 659
Cdd:PRK02224 640 EAEFdeARIEEAREDKERAEEYLEQVEEKLDELREERDDLQaeigaveneleelEELRERREALENRVEALEALYDEAEE 719
|
...
gi 17534555 660 KQT 662
Cdd:PRK02224 720 LES 722
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
202-713 |
8.54e-14 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 76.37 E-value: 8.54e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 202 REKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEFLTPvrKNASKIRELDE-YHQLSAKVIEESM 280
Cdd:pfam01576 12 EELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRA--RLAARKQELEEiLHELESRLEEEEE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 281 NDLKIKNEtlTKELSDKTELVKMKNEELEDLRQ-------TTTASLGDSEQATKYLHEENMKLTRQK-------ADIRCE 346
Cdd:pfam01576 90 RSQQLQNE--KKKMQQHIQDLEEQLDEEEAARQklqlekvTTEAKIKKLEEDILLLEDQNSKLSKERklleeriSEFTSN 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 347 LLEARRKVEGFDKLKQELE---KERDDALADVQKIRE----VKRNVERELQSLTSLMAERDEQIEELKtkmfsFEMIKKD 419
Cdd:pfam01576 168 LAEEEEKAKSLSKLKNKHEamiSDLEERLKKEEKGRQelekAKRKLEGESTDLQEQIAELQAQIAELR-----AQLAKKE 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 420 HE--SAKNELSRTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLES-----------Q 486
Cdd:pfam01576 243 EElqAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELEDtldttaaqqelR 322
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 487 RKVEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSRLAEKTK-GKEDADHLRLTLSQRDSELRSAKKTIQEVKAD 565
Cdd:pfam01576 323 SKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKrNKANLEKAKQALESENAELQAELRTLQQAKQD 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 566 NQKVQLMLVEVRQHQEKILEENVRLRKGMADALAK----IEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQ 641
Cdd:pfam01576 403 SEHKRKKLEGQLQELQARLSESERQRAELAEKLSKlqseLESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETR 482
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 642 Q-------IAESKELVTYLHSQIDAKQTKQPKLGRR-STLLSTVSEMDTSVyMREAEEVRALEEQRQALMSNLAEKRRQL 713
Cdd:pfam01576 483 QklnlstrLRQLEDERNSLQEQLEEEEEAKRNVERQlSTLQAQLSDMKKKL-EEDAGTLEALEEGKKRLQRELEALTQQL 561
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
368-674 |
3.82e-13 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 74.20 E-value: 3.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 368 RDDALadvQKIREVKRNVERelqsLTSLMAERDEQIEELKT--------KMFSFEMIKKDHESAKNELSRTQEKLDQMGK 439
Cdd:COG1196 174 KEEAE---RKLEATEENLER----LEDILGELERQLEPLERqaekaeryRELKEELKELEAELLLLKLRELEAELEELEA 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 440 HLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQtslESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVHL 519
Cdd:COG1196 247 ELEELEAELEELEAELAELEAELEELRLELEELELELEEAQ---AEEYELLAELARLEQDIARLEERRRELEERLEELEE 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 520 DYRQELSRLAEKtkgKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALA 599
Cdd:COG1196 324 ELAELEEELEEL---EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17534555 600 KIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQPKLGRRSTLL 674
Cdd:COG1196 401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALL 475
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
45-681 |
8.05e-13 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 73.55 E-value: 8.05e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 45 EDLKKRVLDAENIIQDLRSERDALHETLvdkaGLNESVIIEQSKRVSTQETRIYRRDVNLLEDDLKHHQSQIRILQNKCS 124
Cdd:TIGR02168 368 EELESRLEELEEQLETLRSKVAQLELQI----ASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELE 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 125 TLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVtKDLHDKNE-------------------- 184
Cdd:TIGR02168 444 ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEgfsegvkallknqsglsgil 522
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 185 ----ELTSFRMEYVTKLSEANRE--KKALEEKLEKYKND---MKENDR--------KSLELNKEQVTTQNVLSE----VR 243
Cdd:TIGR02168 523 gvlsELISVDEGYEAAIEAALGGrlQAVVVENLNAAKKAiafLKQNELgrvtflplDSIKGTEIQGNDREILKNiegfLG 602
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 244 QLSAHFEFLTPVRKN--------------ASKIRELDEYHQLSAKVI-----------------EESMNDLKIKNE--TL 290
Cdd:TIGR02168 603 VAKDLVKFDPKLRKAlsyllggvlvvddlDNALELAKKLRPGYRIVTldgdlvrpggvitggsaKTNSSILERRREieEL 682
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 291 TKELSDKTELVKMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADirceLLEARRKVEGFDKLKQELEKERDD 370
Cdd:TIGR02168 683 EEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKD----LARLEAEVEQLEERIAQLSKELTE 758
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 371 ALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSfemIKKDHESAKNELSRTQEKLDQmgkhlimadqqcst 450
Cdd:TIGR02168 759 LEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKA---LREALDELRAELTLLNEEAAN-------------- 821
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 451 fksLKESAEGSRRRAIEQcnemvvrIRDLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVhldyrqelsrLAE 530
Cdd:TIGR02168 822 ---LRERLESLERRIAAT-------ERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL----------LNE 881
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 531 KTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEEnvrlRKGMADALAkiEEYKRSWQN 610
Cdd:TIGR02168 882 RASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVR----IDNLQERLS--EEYSLTLEE 955
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17534555 611 SQETCERLERESATKEDKLDKLEEELQE-------KKQQIAESKELVTYLHSQI-DAKQTKQpklgrrsTLLSTVSEMD 681
Cdd:TIGR02168 956 AEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELKERYDFLTAQKeDLTEAKE-------TLEEAIEEID 1027
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
45-715 |
1.10e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 72.79 E-value: 1.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 45 EDLKKRVLDAENIIQDLRSERDalhETLVDKAGLNESVIIEQSKRVSTQETRIYRRDV-NLLEDDLKHHQSQIRILQNKC 123
Cdd:TIGR02169 311 AEKERELEDAEERLAKLEAEID---KLLAEIEELEREIEEERKRRDKLTEEYAELKEElEDLRAELEEVDKEFAETRDEL 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 124 STLEMEKQTLQE---TIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELTSFRMEYVTKLSEA 200
Cdd:TIGR02169 388 KDYREKLEKLKReinELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 201 NREKKALEEKLEKYKNDMKEndrKSLELNKEQVTTQNVLSEVRQLSAHFEFLTPVRKNA-SKIRELDEYHQLSAKVIEES 279
Cdd:TIGR02169 468 EQELYDLKEEYDRVEKELSK---LQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhGTVAQLGSVGERYATAIEVA 544
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 280 ----MNDLKIKNETLTKE----LSDKT-------ELVKMKNEELEDLRQTTTASLGDS----------EQATKY-----L 329
Cdd:TIGR02169 545 agnrLNNVVVEDDAVAKEaielLKRRKagratflPLNKMRDERRDLSILSEDGVIGFAvdlvefdpkyEPAFKYvfgdtL 624
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 330 HEENMKLTRQKAD------IRCELLE----------ARRKVEGF-----DKL------KQELEKERDDALADVQKIrevk 382
Cdd:TIGR02169 625 VVEDIEAARRLMGkyrmvtLEGELFEksgamtggsrAPRGGILFsrsepAELqrlrerLEGLKRELSSLQSELRRI---- 700
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 383 rnvERELQSLTSLMAERDEQIEELKTKMfsfEMIKKDHESAKNELSRTQEKLDQMgkhlimaDQQCSTFKSLKESAEGSR 462
Cdd:TIGR02169 701 ---ENRLDELSQELSDASRKIGEIEKEI---EQLEQEEEKLKERLEELEEDLSSL-------EQEIENVKSELKELEARI 767
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 463 RRAIEQCNEMVVRIRDLQTSLESQR--KVEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDyrqelsrlaektkgKEDADH 540
Cdd:TIGR02169 768 EELEEDLHKLEEALNDLEARLSHSRipEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE--------------KEYLEK 833
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 541 LRLTLSQRDSELRSAKKTI-QEVKADNQKVQLMLVEVRQHQEKILE---ENVRLRKGMADALAKIEEYKRSWQNSQETCE 616
Cdd:TIGR02169 834 EIQELQEQRIDLKEQIKSIeKEIENLNGKKEELEEELEELEAALRDlesRLGDLKKERDELEAQLRELERKIEELEAQIE 913
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 617 RLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQpKLGRRSTLLSTVSEMDTSVYMREAEEVRALE 696
Cdd:TIGR02169 914 KKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQ-RVEEEIRALEPVNMLAIQEYEEVLKRLDELK 992
|
730
....*....|....*....
gi 17534555 697 EQRQALMsnlaEKRRQLVD 715
Cdd:TIGR02169 993 EKRAKLE----EERKAILE 1007
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
84-713 |
3.81e-12 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 71.33 E-value: 3.81e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 84 IEQSKRVSTQETRIYRRDVNLLEDDLKHHQSQIRilQNKCSTLEMEKQTLQETIQRAQDDKKETETELEssrsrlhvlEK 163
Cdd:PTZ00121 1029 IEELTEYGNNDDVLKEKDIIDEDIDGNHEGKAEA--KAHVGQDEGLKPSYKDFDFDAKEDNRADEATEE---------AF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 164 ELSAKANDIFMVTKDLHDKNEELTSfRMEYVTKLSEANR--EKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQnvLSE 241
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKK-KAEDARKAEEARKaeDARKAEEARKAEDAKRVEIARKAEDARKAEEARK--AED 1174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 242 VRQLSAHFEFLTpVRKnASKIRELDEYHQLSAKVIEEsmNDLKIKnETLTKELSDKTELVKMKNEELEDLRQTTTAS-LG 320
Cdd:PTZ00121 1175 AKKAEAARKAEE-VRK-AEELRKAEDARKAEAARKAE--EERKAE-EARKAEDAKKAEAVKKAEEAKKDAEEAKKAEeER 1249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 321 DSEQATKYLHEENMKLTRQKADIRCEllEARRKvegfDKLKQELEKERDDAL---ADVQKIREVKRNVE--RELQSLTSL 395
Cdd:PTZ00121 1250 NNEEIRKFEEARMAHFARRQAAIKAE--EARKA----DELKKAEEKKKADEAkkaEEKKKADEAKKKAEeaKKADEAKKK 1323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 396 MAERDEQIEELKTKMfsfEMIKKDHESAKNELSRTQEKLDQMGKHLIMADQQCStfkSLKESAEGSRRRAieqcnEMVVR 475
Cdd:PTZ00121 1324 AEEAKKKADAAKKKA---EEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKE---EAKKKADAAKKKA-----EEKKK 1392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 476 IRDLQTSLESQRKVEQEVEMLKAENsrqaKKIEFMKEEIQEVhldyrQELSRLAEKTKGKEDADHLRLTLSQRDSELRSA 555
Cdd:PTZ00121 1393 ADEAKKKAEEDKKKADELKKAAAAK----KKADEAKKKAEEK-----KKADEAKKKAEEAKKADEAKKKAEEAKKAEEAK 1463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 556 KKTIQEVKADNQKVQLMlvEVRQHQEkileenvrLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEE 635
Cdd:PTZ00121 1464 KKAEEAKKADEAKKKAE--EAKKADE--------AKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEA 1533
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17534555 636 LQEKKQQIAESKELVTYLHSQIDAKQTKQpklgRRSTLLSTVSEMDTSVYMREAEEVRALEEQRQALMSNLAEKRRQL 713
Cdd:PTZ00121 1534 KKADEAKKAEEKKKADELKKAEELKKAEE----KKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
347-652 |
7.01e-12 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 70.48 E-value: 7.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 347 LLEARRKVEGFDKLKQELEK-ERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMfsfemikkdhESAKN 425
Cdd:TIGR02169 203 LRREREKAERYQALLKEKREyEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRL----------EEIEQ 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 426 ELSRTQEKLDQMGkhlimaDQQCSTFKSLKESAEGSR---RRAIEQCNEMVVRIRDLQTSLESQR-KVEQEVEMLKAENS 501
Cdd:TIGR02169 273 LLEELNKKIKDLG------EEEQLRVKEKIGELEAEIaslERSIAEKERELEDAEERLAKLEAEIdKLLAEIEELEREIE 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 502 RQAKKIEFMKEEIQEVHLDYRQELSRLAEKTKgkeDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQE 581
Cdd:TIGR02169 347 EERKRRDKLTEEYAELKEELEDLRAELEEVDK---EFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELA 423
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 582 KILEENVRLRKGM----ADALAKIEEYKRSWQNSQETCERLERESATK----------EDKLDKLEEELQEKKQQIAESK 647
Cdd:TIGR02169 424 DLNAAIAGIEAKIneleEEKEDKALEIKKQEWKLEQLAADLSKYEQELydlkeeydrvEKELSKLQRELAEAEAQARASE 503
|
....*
gi 17534555 648 ELVTY 652
Cdd:TIGR02169 504 ERVRG 508
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
475-749 |
1.42e-11 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 69.20 E-value: 1.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 475 RIRDLQTSLESQRKVeqevemLKAEnSRQAKKIEFMKEEIQEVHL--------DYRQELSRL-AEKTKGKEDADHLRLTL 545
Cdd:COG1196 190 RLEDILGELERQLEP------LERQ-AEKAERYRELKEELKELEAellllklrELEAELEELeAELEELEAELEELEAEL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 546 SQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATK 625
Cdd:COG1196 263 AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEEL 342
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 626 EDKLDKLEEELQEKKQQIAESKElvtylhSQIDAKQTKQPKLGRRSTLLSTVSEMdtsvyMREAEEVRALEEQRQALMSN 705
Cdd:COG1196 343 EEELEEAEEELEEAEAELAEAEE------ALLEAEAELAEAEEELEELAEELLEA-----LRAAAELAAQLEELEEAEEA 411
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 17534555 706 LAEKRRQLVDSKKSQSTANTTIVTTTTTEISKSSQSASELSNRQ 749
Cdd:COG1196 412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
45-649 |
4.01e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.79 E-value: 4.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 45 EDLKKRVLDAENIIQDLRSERDALHETLVDKAGLNESVIIEQSKRVS-----TQETRIYRRDVNLLEDDLKHHQSQIRIL 119
Cdd:TIGR02169 346 EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREkleklKREINELKRELDRLQEELQRLSEELADL 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 120 QNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELTSFRMEyVTKLSE 199
Cdd:TIGR02169 426 NAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ-ARASEE 504
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 200 ANREKKALEEKLEKYKN----------DMKENDRKSLE------LNKEQVTTQNVLSEVRQL-----SAHFEFLtPVRKN 258
Cdd:TIGR02169 505 RVRGGRAVEEVLKASIQgvhgtvaqlgSVGERYATAIEvaagnrLNNVVVEDDAVAKEAIELlkrrkAGRATFL-PLNKM 583
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 259 ASKIRELD---------------EYHQLSAKVIEESMND-LKIKNETLTKELSDKTELVKMKNEELE------------D 310
Cdd:TIGR02169 584 RDERRDLSilsedgvigfavdlvEFDPKYEPAFKYVFGDtLVVEDIEAARRLMGKYRMVTLEGELFEksgamtggsrapR 663
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 311 LRQTTTASLGDSEQAtkyLHEENMKLTRQKADIRCELLEARRKV-EGFDKLK------QELEKERDDALADVQKIREVKR 383
Cdd:TIGR02169 664 GGILFSRSEPAELQR---LRERLEGLKRELSSLQSELRRIENRLdELSQELSdasrkiGEIEKEIEQLEQEEEKLKERLE 740
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 384 NVERELQSLtslmaerDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMgkhliMADQQCSTFKSLKESAEGSRR 463
Cdd:TIGR02169 741 ELEEDLSSL-------EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEAR-----LSHSRIPEIQAELSKLEEEVS 808
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 464 RAIEQCNEMVVRIRDLQTSLESqrkVEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSRLAEKTKGKEDAD---- 539
Cdd:TIGR02169 809 RIEARLREIEQKLNRLTLEKEY---LEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLEsrlg 885
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 540 HLRLTLSQRDSELRSAKKTIQEVKAD------NQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQE 613
Cdd:TIGR02169 886 DLKKERDELEAQLRELERKIEELEAQiekkrkRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEE 965
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|
gi 17534555 614 TCERL---------ERESATK-----EDKLDKLEEELQEKKQQIAESKEL 649
Cdd:TIGR02169 966 EIRALepvnmlaiqEYEEVLKrldelKEKRAKLEEERKAILERIEEYEKK 1015
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
129-672 |
4.22e-11 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 67.86 E-value: 4.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 129 EKQTLQETIQRAQDDKK--ETETELESSRSRLHVLEKELSAKANdifmvTKDLHDKNEELTSFRMEYVTKLSEANREKKA 206
Cdd:PTZ00121 1300 EKKKADEAKKKAEEAKKadEAKKKAEEAKKKADAAKKKAEEAKK-----AAEAAKAEAEAAADEAEAAEEKAEAAEKKKE 1374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 207 LEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEFLTPVRKNASKIRELDEYHQLS--AKVIEESMN--D 282
Cdd:PTZ00121 1375 EAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAeeAKKADEAKKkaE 1454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 283 LKIKNETLTK--ELSDKTELVKMKNEE---LEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEG- 356
Cdd:PTZ00121 1455 EAKKAEEAKKkaEEAKKADEAKKKAEEakkADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAk 1534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 357 -FDKLKQELEKERDDALADVQKIR--EVKRNVER-----ELQSLTSLMAERDEQIEElkTKMFSFEMIKKDHESAKNELS 428
Cdd:PTZ00121 1535 kADEAKKAEEKKKADELKKAEELKkaEEKKKAEEakkaeEDKNMALRKAEEAKKAEE--ARIEEVMKLYEEEKKMKAEEA 1612
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 429 RTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAieqcnemvvrirdlqtslESQRKVEQEVEMLKAENSRQAKKIE 508
Cdd:PTZ00121 1613 KKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKA------------------EELKKAEEENKIKAAEEAKKAEEDK 1674
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 509 FMKEEIQEVHLDYRQELSRLAEKTKGKEDADHLRltlsqrdselrsaKKTIQEVKADNQkvqlmlvevrqhqekileenv 588
Cdd:PTZ00121 1675 KKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELK-------------KKEAEEKKKAEE--------------------- 1720
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 589 rLRKGMADALAKIEEYKRSWQNSQETCERLERESATKeDKLDKLEEELQEKKQQIAESKELVtyLHSQIDAKQTKQPKLG 668
Cdd:PTZ00121 1721 -LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK-KKIAHLKKEEEKKAEEIRKEKEAV--IEEELDEEDEKRRMEV 1796
|
....
gi 17534555 669 RRST 672
Cdd:PTZ00121 1797 DKKI 1800
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
129-511 |
4.67e-11 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 67.79 E-value: 4.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 129 EKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELTSFRmeyvTKLSEANREKKALE 208
Cdd:TIGR02169 682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELE----EDLSSLEQEIENVK 757
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 209 EKLEKYKndmKENDRKSLELNKEQVTTQNVLSEVRQlsahfeflTPVRKNASKIRELDEYHQlsakVIEESMNDLkiknE 288
Cdd:TIGR02169 758 SELKELE---ARIEELEEDLHKLEEALNDLEARLSH--------SRIPEIQAELSKLEEEVS----RIEARLREI----E 818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 289 TLTKELSDKTELVKMKNEELEDLRQTTTASLGDSEQAtkylhEENMKLtrQKADIRCELLEARRKVEGFDKLKQELEKER 368
Cdd:TIGR02169 819 QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE-----IENLNG--KKEELEEELEELEAALRDLESRLGDLKKER 891
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 369 DDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFE-MIKKDHESAKNELS--RTQEKLDQMGKHLimad 445
Cdd:TIGR02169 892 DELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEdPKGEDEEIPEEELSleDVQAELQRVEEEI---- 967
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17534555 446 qqcstfkslkESAEGSRRRAIEQCNEMVVRIRDLQtslESQRKVEQEVEMLK--AENSRQAKKIEFMK 511
Cdd:TIGR02169 968 ----------RALEPVNMLAIQEYEEVLKRLDELK---EKRAKLEEERKAILerIEEYEKKKREVFME 1022
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
449-720 |
4.98e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 67.39 E-value: 4.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 449 STFKSLKESAEgsrrRAIEQCNEMVVRIRDLQTSLESQrkveqeVEMLKAEnSRQAKKIEFMKEEIQEVHLDYRqelsrL 528
Cdd:TIGR02168 168 SKYKERRKETE----RKLERTRENLDRLEDILNELERQ------LKSLERQ-AEKAERYKELKAELRELELALL-----V 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 529 AEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSW 608
Cdd:TIGR02168 232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 609 QNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQPKLGRRSTLLSTVSEmdtsvymRE 688
Cdd:TIGR02168 312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLE-------TL 384
|
250 260 270
....*....|....*....|....*....|..
gi 17534555 689 AEEVRALEEQRQALMSNLAEKRRQLVDSKKSQ 720
Cdd:TIGR02168 385 RSKVAQLELQIASLNNEIERLEARLERLEDRR 416
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
32-661 |
1.27e-10 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 66.30 E-value: 1.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 32 SPFQVIDLNNESHEDlkkRVLDA-ENIIQDLR---SERDALHETlvDKAGLNESVIIEQSKRVSTQETR-----IYRRDv 102
Cdd:pfam15921 63 SPRKIIAYPGKEHIE---RVLEEySHQVKDLQrrlNESNELHEK--QKFYLRQSVIDLQTKLQEMQMERdamadIRRRE- 136
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 103 NLLEDDLKHHqsqiriLQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKEL----SAKANDIF----M 174
Cdd:pfam15921 137 SQSQEDLRNQ------LQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILvdfeEASGKKIYehdsM 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 175 VTKDLHDKNEELTSFRMEYVTKLSEANREKKALEEKLEKYKNDMKendrkslelNKEQVTTQNVLSEVRQL-SAHFEFLT 253
Cdd:pfam15921 211 STMHFRSLGSAISKILRELDTEISYLKGRIFPVEDQLEALKSESQ---------NKIELLLQQHQDRIEQLiSEHEVEIT 281
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 254 PVRKNASKIRELDEYHQLSAKVIEESMNDlkiKNETLTKELSDKTELVKMKNEELEDlrqtttaslgdseqaTKYLHEEN 333
Cdd:pfam15921 282 GLTEKASSARSQANSIQSQLEIIQEQARN---QNSMYMRQLSDLESTVSQLRSELRE---------------AKRMYEDK 343
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 334 MK-LTRQKADIRCELLEARRKVEGFDKLKQELEKERDDALADVQKiREVKRNVER------------------------- 387
Cdd:pfam15921 344 IEeLEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHK-REKELSLEKeqnkrlwdrdtgnsitidhlrreld 422
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 388 ----ELQSLTSLM--------AERDEQIEELKTKMFSFEMIKK---DHESAKNELSRTQEKLDQMGKHLIMADQQCSTFK 452
Cdd:pfam15921 423 drnmEVQRLEALLkamksecqGQMERQMAAIQGKNESLEKVSSltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLT 502
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 453 -SLKEsaegsRRRAIEQCNEMVVRIRD-----------LQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEI----QE 516
Cdd:pfam15921 503 aSLQE-----KERAIEATNAEITKLRSrvdlklqelqhLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIenmtQL 577
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 517 VHLDYRQELSRLAEKTKGKEDADHLRLTLSQ-------RDSELRSAKKTIQEVKAdnQKVQLM---------LVEVRQHQ 580
Cdd:pfam15921 578 VGQHGRTAGAMQVEKAQLEKEINDRRLELQEfkilkdkKDAKIRELEARVSDLEL--EKVKLVnagserlraVKDIKQER 655
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 581 EKILEENVRLRKGMADALAKIEEYKRSWQNSQE----TCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQ 656
Cdd:pfam15921 656 DQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEemetTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQ 735
|
....*
gi 17534555 657 IDAKQ 661
Cdd:pfam15921 736 ITAKR 740
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
213-583 |
2.55e-10 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 65.08 E-value: 2.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 213 KYKNDMKENDRK--SLELNKEQVttQNVLSEV-RQLsahfEFLTPVRKNASKIRELDEyhQLSAKVIEESMNDLKIKNEt 289
Cdd:TIGR02168 169 KYKERRKETERKleRTRENLDRL--EDILNELeRQL----KSLERQAEKAERYKELKA--ELRELELALLVLRLEELRE- 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 290 ltkELSDKTELVKMKNEELEDLRQTTTASLGDSEQATKYLHEenmkLTRQKADIRCELLEARRKVEGFDKLKQELEKERD 369
Cdd:TIGR02168 240 ---ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE----LEEEIEELQKELYALANEISRLEQQKQILRERLA 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 370 DALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKtkmfsfemikKDHESAKNELSRTQEKLDQMGKHLIMADQQCS 449
Cdd:TIGR02168 313 NLERQLEELEAQLEELESKLDELAEELAELEEKLEELK----------EELESLEAELEELEAELEELESRLEELEEQLE 382
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 450 TFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLE--SQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSR 527
Cdd:TIGR02168 383 TLRSKVAQLELQIASLNNEIERLEARLERLEDRRErlQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEA 462
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 17534555 528 LAEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKI 583
Cdd:TIGR02168 463 LEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGL 518
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
39-531 |
4.67e-10 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 64.02 E-value: 4.67e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 39 LNNESHEDLKKRVLDAENIIQDLRSERDALHETLVDKAGLNEsvIIEQSKRVSTQETRIyRRDVNLLEDDLKHHQSQIRI 118
Cdd:COG4717 51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAE--LQEELEELEEELEEL-EAELEELREELEKLEKLLQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 119 LQ--NKCSTLEMEKQTLQETIQRAQDDK---KETETELESSRSRLHVLEKELSAKANDI-FMVTKDLHDKNEELTSFRME 192
Cdd:COG4717 128 LPlyQELEALEAELAELPERLEELEERLeelRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEELQQR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 193 yvtkLSEANREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSeVRQLSAHFEFLTPVRKNASKIRELDEYHQLS 272
Cdd:COG4717 208 ----LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLL-LLIAAALLALLGLGGSLLSLILTIAGVLFLV 282
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 273 AKVIEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQT----------TTASLGDSEQATKYLHEENMKLTRQKAD 342
Cdd:COG4717 283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELlaalglppdlSPEELLELLDRIEELQELLREAEELEEE 362
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 343 IRCELLEARRKvEGFDKLKQELEKERDDALADVQKIREVKRnverELQSLTSLMAERDEQIEELkTKMFSFEMIKKDHES 422
Cdd:COG4717 363 LQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQELKE----ELEELEEQLEELLGELEEL-LEALDEEELEEELEE 436
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 423 AKNELSRTQEKLDQMGKhlimadqqcstfkslkesaegsRRRAIEQcnemvvRIRDLQTSLESQRKvEQEVEMLKAENSR 502
Cdd:COG4717 437 LEEELEELEEELEELRE----------------------ELAELEA------ELEQLEEDGELAEL-LQELEELKAELRE 487
|
490 500 510
....*....|....*....|....*....|....*.
gi 17534555 503 QAKKI-------EFMKEEIQEVHLDYRQELSRLAEK 531
Cdd:COG4717 488 LAEEWaalklalELLEEAREEYREERLPPVLERASE 523
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
42-638 |
8.22e-10 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 63.66 E-value: 8.22e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 42 ESHEDLKKRVLDAENIIQDLRSERDALHETLVDKAGL-NESViiEQSKRVSTQETRiyrrdvnlLEDDLKHHQSQIRILQ 120
Cdd:pfam01576 19 ERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELcAEAE--EMRARLAARKQE--------LEEILHELESRLEEEE 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 121 NKCSTLEMEKQTLQETIQraqdDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELtsfrmeyvtklsea 200
Cdd:pfam01576 89 ERSQQLQNEKKKMQQHIQ----DLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKL-------------- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 201 NREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEV-----RQLSAHFEFLTPVRKNASKIRELDEYHQLSAKV 275
Cdd:pfam01576 151 SKERKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLeerlkKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQ 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 276 IEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQtTTASLGDSEQATkylheENMKLTRQKADIRC----ELLEAr 351
Cdd:pfam01576 231 IAELRAQLAKKEEELQAALARLEEETAQKNNALKKIRE-LEAQISELQEDL-----ESERAARNKAEKQRrdlgEELEA- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 352 RKVEGFDKL-----KQELEKERDDALADVQK-IREVKRNVERELQSL----TSLMAERDEQIEELKTKMFSFEMIKKDHE 421
Cdd:pfam01576 304 LKTELEDTLdttaaQQELRSKREQEVTELKKaLEEETRSHEAQLQEMrqkhTQALEELTEQLEQAKRNKANLEKAKQALE 383
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 422 SAKNELSrtqekldqmgkhlimadQQCSTFKSLKESAEGSRRRAIEQCNEMVVRI----RDLQTSLESQRKVEQEVEMLK 497
Cdd:pfam01576 384 SENAELQ-----------------AELRTLQQAKQDSEHKRKKLEGQLQELQARLseseRQRAELAEKLSKLQSELESVS 446
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 498 AE-NSRQAKKIEFMKEEIQ-EVHLDYRQELsrLAEKTKGKedadhlrLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVE 575
Cdd:pfam01576 447 SLlNEAEGKNIKLSKDVSSlESQLQDTQEL--LQEETRQK-------LNLSTRLRQLEDERNSLQEQLEEEEEAKRNVER 517
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17534555 576 VRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQE 638
Cdd:pfam01576 518 QLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRLQQ 580
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
144-650 |
9.20e-10 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 63.20 E-value: 9.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 144 KKETETELESSRSRLHVLEKELSAKANDIfmvtKDLHDKNEELTSFRMEYVTKLSEANREKKALE--------------E 209
Cdd:pfam05483 94 KVSIEAELKQKENKLQENRKIIEAQRKAI----QELQFENEKVSLKLEEEIQENKDLIKENNATRhlcnllketcarsaE 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 210 KLEKYKNDMKENDRKSLELNK--EQVTTQNVLSEVRQLSAHFEFLTPVRKNASKIRELDEYHQLSAKVIEESMNDLKIKN 287
Cdd:pfam05483 170 KTKKYEYEREETRQVYMDLNNniEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQI 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 288 ETLTKELSDKTELVKMKNEELEDLRQTTTaslgdseqatkyLHEENMKLTRQKadircellearrkvegfdklKQELEKE 367
Cdd:pfam05483 250 TEKENKMKDLTFLLEESRDKANQLEEKTK------------LQDENLKELIEK--------------------KDHLTKE 297
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 368 RDDALADVQKIREVKRNVERELQ----SLTSLMAERDEQIEELKTKMFSFEMIKKDHESAK---NELSRT-QEKLDQMGK 439
Cdd:pfam05483 298 LEDIKMSLQRSMSTQKALEEDLQiatkTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTcslEELLRTeQQRLEKNED 377
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 440 HLimadqQCSTFKSLKESAEgsrrraieqCNEMVVRIRDLQTSLESQRKVEQEVEMLKAENsrqaKKIEFMKEEIQevhl 519
Cdd:pfam05483 378 QL-----KIITMELQKKSSE---------LEEMTKFKNNKEVELEELKKILAEDEKLLDEK----KQFEKIAEELK---- 435
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 520 DYRQELSRLAEkTKGKEDADhLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALA 599
Cdd:pfam05483 436 GKEQELIFLLQ-AREKEIHD-LEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTL 513
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|.
gi 17534555 600 KIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELV 650
Cdd:pfam05483 514 ELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEV 564
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
144-713 |
1.13e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.03 E-value: 1.13e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 144 KKETETELESSRSRLHVLE-----------------------KELSAKAN--DIFMVTKDLHDKNEELTSFRMEYV---T 195
Cdd:COG1196 174 KEEAERKLEATEENLERLEdilgelerqleplerqaekaeryRELKEELKelEAELLLLKLRELEAELEELEAELEeleA 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 196 KLSEANREKKALEEKLEKYKndmKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEFLTPVRKNASkiRELDEYhQLSAKV 275
Cdd:COG1196 254 ELEELEAELAELEAELEELR---LELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELE--ERLEEL-EEELAE 327
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 276 IEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQT---TTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARR 352
Cdd:COG1196 328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAlleAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEE 407
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 353 KVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELktkmfsfemiKKDHESAKNELSRTQE 432
Cdd:COG1196 408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----------LELLAELLEEAALLEA 477
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 433 KLDQMGKHLIMADQQCSTFKSLKESAEG----SRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKA------ENSR 502
Cdd:COG1196 478 ALAELLEELAEAAARLLLLLEAEADYEGflegVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAAlqnivvEDDE 557
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 503 QAKK-IEFMKEEIQ----EVHLDyRQELSRLAEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVR 577
Cdd:COG1196 558 VAAAaIEYLKAAKAgratFLPLD-KIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAAL 636
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 578 QHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQI 657
Cdd:COG1196 637 RRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEER 716
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|....*.
gi 17534555 658 DAKQTKQPKLGRRSTLLSTVSEMDTSVYMREAEEVRALEEQRQALMSNLAEKRRQL 713
Cdd:COG1196 717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERL 772
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
45-583 |
1.34e-09 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 62.61 E-value: 1.34e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 45 EDLKKRVLDAENIIQDLRSERDALHETLVDKAGLNESVIIEQSKRVSTQETRiyrRDVNLLEDDLKHHQSQIRILQNKCS 124
Cdd:PRK01156 190 EKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSAL---NELSSLEDMKNRYESEIKTAESDLS 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 125 TLEMEKQTLQETIQRAqddKKETETELESSRSRLhvlekelsakaNDIFMVTKDLHDKNEELTSFRMEyVTKLSEANREK 204
Cdd:PRK01156 267 MELEKNNYYKELEERH---MKIINDPVYKNRNYI-----------NDYFKYKNDIENKKQILSNIDAE-INKYHAIIKKL 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 205 kaleEKLEKYKNDMKENDRKSLELNKEqvttqnvLSEVRQLSAHFEFLtpvrknaskireLDEYHQLSAKVIEESMNDLK 284
Cdd:PRK01156 332 ----SVLQKDYNDYIKKKSRYDDLNNQ-------ILELEGYEMDYNSY------------LKSIESLKKKIEEYSKNIER 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 285 IK---NETLTKELSDKTELVKMKNEELEDLRQTTTaSLGDSEQATKYLHEENMKLTRQKADI----RCELL-------EA 350
Cdd:PRK01156 389 MSafiSEILKIQEIDPDAIKKELNEINVKLQDISS-KVSSLNQRIRALRENLDELSRNMEMLngqsVCPVCgttlgeeKS 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 351 RRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAER----DEQIE----ELKTKMFSFEMIKKDH-- 420
Cdd:PRK01156 468 NHIINHYNEKKSRLEEKIREIEIEVKDIDEKIVDLKKRKEYLESEEINKsineYNKIEsaraDLEDIKIKINELKDKHdk 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 421 -ESAKNEL-SRTQEKLDQMGKHLIMADQQCS-----TFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQ-RKVEQE 492
Cdd:PRK01156 548 yEEIKNRYkSLKLEDLDSKRTSWLNALAVISlidieTNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSiREIENE 627
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 493 VEMLKAE-NSRQAKKIefMKEEIQEVHLDYRqelSRLAEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQL 571
Cdd:PRK01156 628 ANNLNNKyNEIQENKI--LIEKLRGKIDNYK---KQIAEIDSIIPDLKEITSRINDIEDNLKKSRKALDDAKANRARLES 702
|
570
....*....|..
gi 17534555 572 MLVEVRQHQEKI 583
Cdd:PRK01156 703 TIEILRTRINEL 714
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
104-713 |
3.25e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.62 E-value: 3.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 104 LLEDDLKHHQSQIRILQNKCSTLEMEKQTLQETIQraqddkkETETELESSRSRLHVLEKELSAKAND-IFMVTKDLHdk 182
Cdd:TIGR02169 227 ELLKEKEALERQKEAIERQLASLEEELEKLTEEIS-------ELEKRLEEIEQLLEELNKKIKDLGEEeQLRVKEKIG-- 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 183 neELTSFRMEYVTKLSEANREKKALEEKLEKYKNDMKENDRKSLELnKEQVTTQNVlsEVRQLSAHFEFLTpvrknaski 262
Cdd:TIGR02169 298 --ELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL-EREIEEERK--RRDKLTEEYAELK--------- 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 263 relDEYHQLSAKVIEESmndlkIKNETLTKELSDKTELVKMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKAD 342
Cdd:TIGR02169 364 ---EELEDLRAELEEVD-----KEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAK 435
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 343 IRceLLEARRKVEGfDKLKqELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKmfsfemiKKDHES 422
Cdd:TIGR02169 436 IN--ELEEEKEDKA-LEIK-KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQ-------ARASEE 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 423 AKNELSRTQEKLDQMGK-------HLIMADQQcstFKSLKESAEGSRRRAI--------EQC-----------------N 470
Cdd:TIGR02169 505 RVRGGRAVEEVLKASIQgvhgtvaQLGSVGER---YATAIEVAAGNRLNNVvveddavaKEAiellkrrkagratflplN 581
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 471 EMVVRIRDLQ-----------------------------------TSLESQRKVEQEVEMLKAE---------------- 499
Cdd:TIGR02169 582 KMRDERRDLSilsedgvigfavdlvefdpkyepafkyvfgdtlvvEDIEAARRLMGKYRMVTLEgelfeksgamtggsra 661
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 500 ------NSRQAK-KIEFMKEEIQEVhldyRQELSRL-AEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQL 571
Cdd:TIGR02169 662 prggilFSRSEPaELQRLRERLEGL----KRELSSLqSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE 737
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 572 MLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESA-----TKEDKLDKLEEELQEKKQQIAE- 645
Cdd:TIGR02169 738 RLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLShsripEIQAELSKLEEEVSRIEARLREi 817
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17534555 646 ------SKELVTYLHSQIDAKQTKQPKL-GRRSTLLSTVSEMDTSV--YMREAEEVRALEEQRQALMSNLAEKRRQL 713
Cdd:TIGR02169 818 eqklnrLTLEKEYLEKEIQELQEQRIDLkEQIKSIEKEIENLNGKKeeLEEELEELEAALRDLESRLGDLKKERDEL 894
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
37-605 |
3.65e-09 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 61.28 E-value: 3.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 37 IDLNNesheDLKKRVLDAENIIQDLRSERDALHETLVDKAGLNESVIIEQSKRVSTQETRIYRRDVNLLEDDLKHHQSQI 116
Cdd:pfam05483 186 MDLNN----NIEKMILAFEELRVQAENARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTF 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 117 RILQNKCSTLEMEKQT------LQETIQRAQDDKKETE---TELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELT 187
Cdd:pfam05483 262 LLEESRDKANQLEEKTklqdenLKELIEKKDHLTKELEdikMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELN 341
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 188 SFRMEYVTKLSEANREKKALEEKLekykndmkENDRKSLELNKEQVTTqnVLSEVRQLSAHFEFLTPVRKNasKIRELDE 267
Cdd:pfam05483 342 KAKAAHSFVVTEFEATTCSLEELL--------RTEQQRLEKNEDQLKI--ITMELQKKSSELEEMTKFKNN--KEVELEE 409
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 268 YHQLSAKviEESMNDLKIKNETLTKELSDKTE----LVKMKNEELEDLRQTTTASLGDSEQATKYLHE-----ENMKLTR 338
Cdd:pfam05483 410 LKKILAE--DEKLLDEKKQFEKIAEELKGKEQelifLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDlktelEKEKLKN 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 339 QKADIRCE--LLEARRKVEGFDKLKQELEKERDD----------ALADVQKIREVKRNVERELQSLTSLMAERDEQIE-- 404
Cdd:pfam05483 488 IELTAHCDklLLENKELTQEASDMTLELKKHQEDiinckkqeerMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKck 567
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 405 ----ELKTKMFSFEMIKKDHESA--KNELSRTQEKLDQMGKHLIMADQQCSTFKSlKESAEGsrrraiEQCNEMVVRIRD 478
Cdd:pfam05483 568 ldksEENARSIEYEVLKKEKQMKilENKCNNLKKQIENKNKNIEELHQENKALKK-KGSAEN------KQLNAYEIKVNK 640
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 479 LQTSLESQRK--------VEQEVEMLKAENSRQAKKIEFMKEEIQEV-----HLDYR-----QELSRLAEKTKGKEDAdh 540
Cdd:pfam05483 641 LELELASAKQkfeeiidnYQKEIEDKKISEEKLLEEVEKAKAIADEAvklqkEIDKRcqhkiAEMVALMEKHKHQYDK-- 718
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17534555 541 lrlTLSQRDSEL---------RSAKKTIQEVKADNQKVQLMLVEVRQHQEKilEENVRLRKGMADALAKIEEYK 605
Cdd:pfam05483 719 ---IIEERDSELglyknkeqeQSSAKAALEIELSNIKAELLSLKKQLEIEK--EEKEKLKMEAKENTAILKDKK 787
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
192-569 |
4.08e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 61.24 E-value: 4.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 192 EYVTKLSEANREKKALEEKLEKY--KNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEFLTPVRKNASKIRELDEyh 269
Cdd:TIGR02169 167 EFDRKKEKALEELEEVEENIERLdlIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIER-- 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 270 QLSAkvIEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQ-----------TTTASLGDSEQATKYLHEENMKLTR 338
Cdd:TIGR02169 245 QLAS--LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlrvkekigELEAEIASLERSIAEKERELEDAEE 322
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 339 QKADIRCELLEARRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMfsfEMIKK 418
Cdd:TIGR02169 323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL---EKLKR 399
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 419 DHESAKNELSRTQEKLDQmgkhlimadqqcstfkslkesaegsRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEvEMLKA 498
Cdd:TIGR02169 400 EINELKRELDRLQEELQR-------------------------LSEELADLNAAIAGIEAKINELEEEKEDKAL-EIKKQ 453
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17534555 499 EnsRQAKKIEFMKEEIQEVHLDYRQELSRLAEK-TKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKV 569
Cdd:TIGR02169 454 E--WKLEQLAADLSKYEQELYDLKEEYDRVEKElSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGV 523
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
327-713 |
4.25e-09 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 61.29 E-value: 4.25e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 327 KYLHEENMKLTRQKADIRCELLEARRKVegfdklkQELEKERDdALADVQK--------IREVKRNVERELQSLTSL--- 395
Cdd:pfam15921 92 RRLNESNELHEKQKFYLRQSVIDLQTKL-------QEMQMERD-AMADIRRresqsqedLRNQLQNTVHELEAAKCLked 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 396 -MAERDEQIEELKTKMFSfemikkdHESAKNELSRTQEKLDQMGKHLIMADQQCST--FKSLKESAEGSRRRAIEQCNEM 472
Cdd:pfam15921 164 mLEDSNTQIEQLRKMMLS-------HEGVLQEIRSILVDFEEASGKKIYEHDSMSTmhFRSLGSAISKILRELDTEISYL 236
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 473 VVRIRDLQTSLE-----SQRKVE----------------QEVEML----KAENSR-QAKKIEFMKEEIQEVHLD----YR 522
Cdd:pfam15921 237 KGRIFPVEDQLEalkseSQNKIElllqqhqdrieqliseHEVEITglteKASSARsQANSIQSQLEIIQEQARNqnsmYM 316
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 523 QELSRLAEktkgkedadhlrlTLSQRDSELRSAKKTIQEvKADNQKVQLML-----VEVRQHQEKILEENVRLRKGMADA 597
Cdd:pfam15921 317 RQLSDLES-------------TVSQLRSELREAKRMYED-KIEELEKQLVLanselTEARTERDQFSQESGNLDDQLQKL 382
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 598 LAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHS--------QIDAKQTKQPKLGR 669
Cdd:pfam15921 383 LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSecqgqmerQMAAIQGKNESLEK 462
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 17534555 670 RSTL---LSTVSEMDTSVYMREAEEVRALEEQRQA---LMSNLAEKRRQL 713
Cdd:pfam15921 463 VSSLtaqLESTKEMLRKVVEELTAKKMTLESSERTvsdLTASLQEKERAI 512
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
45-721 |
4.67e-09 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 61.22 E-value: 4.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 45 EDLKKRVLDAENIIQDLRSERDALHETLVDKAGLNESVIIEQSKRVSTQEtrIYRRDVNLLeDDLKHHQSQIRILQNKCS 124
Cdd:TIGR00606 189 ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQITSKEAQLESSRE--IVKSYENEL-DPLKNRLKEIEHNLSKIM 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 125 TLEMEKQTLQETIQRAQDDKKETETELESSrsrLHVLEKELsakaNDIFmvtkdlHDKNEELTSFRMEYV---TKLSEAN 201
Cdd:TIGR00606 266 KLDNEIKALKSRKKQMEKDNSELELKMEKV---FQGTDEQL----NDLY------HNHQRTVREKERELVdcqRELEKLN 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 202 REKKALEEKLEKYKNdmkENDRKSLELNKEQVTTQNVLSEVRQLSAHFEfLTPVRKNASKIRELDEYHQL-------SAK 274
Cdd:TIGR00606 333 KERRLLNQEKTELLV---EQGRLQLQADRHQEHIRARDSLIQSLATRLE-LDGFERGPFSERQIKNFHTLvierqedEAK 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 275 VIEESMNDL--------------KIKNETLTKELSDKTELVKMKNEELEDLRQtttaSLGDSEQATKYLHEENMKLTRQK 340
Cdd:TIGR00606 409 TAAQLCADLqskerlkqeqadeiRDEKKGLGRTIELKKEILEKKQEELKFVIK----ELQQLEGSSDRILELDQELRKAE 484
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 341 ADIrcELLEARRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLM------AERDEQIEELKTKMFSF- 413
Cdd:TIGR00606 485 REL--SKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEmltkdkMDKDEQIRKIKSRHSDEl 562
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 414 ----------EMIKKDHESAKNELSRTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQ------CNEMVVRIR 477
Cdd:TIGR00606 563 tsllgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKlfdvcgSQDEESDLE 642
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 478 DLQTSLESQRK-----------VEQEVEMLKAENS----------RQAKKIEFMKEEIQEVHLDYRQELSRLAEKTKGKE 536
Cdd:TIGR00606 643 RLKEEIEKSSKqramlagatavYSQFITQLTDENQsccpvcqrvfQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKE 722
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 537 DADHLRLTLSQ-RDSELRSAKKTIQEVKADNQKVQLMLVEVR---QHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQ 612
Cdd:TIGR00606 723 KRRDEMLGLAPgRQSIIDLKEKEIPELRNKLQKVNRDIQRLKndiEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELK 802
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 613 ETCERLEREsATKEDKLD------KLEEELQEKK-------QQIAESKELVTYLHSQIDAKQTKQPKLGRRSTLLSTvse 679
Cdd:TIGR00606 803 DVERKIAQQ-AAKLQGSDldrtvqQVNQEKQEKQheldtvvSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGT--- 878
|
730 740 750 760
....*....|....*....|....*....|....*....|..
gi 17534555 680 mdtsvymrEAEEVRALEEQRQALMSNLAEKRRQLVDSKKSQS 721
Cdd:TIGR00606 879 --------NLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDS 912
|
|
| C1 |
smart00109 |
Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains); Some bind phorbol ... |
758-808 |
8.63e-09 |
|
Protein kinase C conserved region 1 (C1) domains (Cysteine-rich domains); Some bind phorbol esters and diacylglycerol. Some bind RasGTP. Zinc-binding domains.
Pssm-ID: 197519 Cd Length: 50 Bit Score: 52.47 E-value: 8.63e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 17534555 758 HKWKAFRHVGvlSMKCSLCFVGIS-AFAKAKKCSHCDVHVHASCAPRVNNTC 808
Cdd:smart00109 1 HKHVFRTFTK--PTFCCVCRKSIWgSFKQGLRCSECKVKCHKKCADKVPKAC 50
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
201-748 |
9.03e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 60.03 E-value: 9.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 201 NREKKALEEKLEKYKNDMK--ENDRKSLE--LNKEQVTTQNVLSEVRQLSAHFEFLT-PVRKNASKIRELDEYhqlSAKV 275
Cdd:TIGR04523 32 DTEEKQLEKKLKTIKNELKnkEKELKNLDknLNKDEEKINNSNNKIKILEQQIKDLNdKLKKNKDKINKLNSD---LSKI 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 276 IEESMND--LKIKNET----LTKELSDKTELVKMKNEELEDLrqtttaslgdsEQATKYLHEENMKLTRQKadircelle 349
Cdd:TIGR04523 109 NSEIKNDkeQKNKLEVelnkLEKQKKENKKNIDKFLTEIKKK-----------EKELEKLNNKYNDLKKQK--------- 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 350 arrkvEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDE---QIEELKTKMF----SFEMIKKDHES 422
Cdd:TIGR04523 169 -----EELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNKSlesQISELKKQNNqlkdNIEKKQQEINE 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 423 AKNELSRTQEKLDQmgkhliMADQQCSTFKSLKEsaegsRRRAIEQCNEMVvrirdlqTSLESQRKvEQEVEMLKAENSR 502
Cdd:TIGR04523 244 KTTEISNTQTQLNQ------LKDEQNKIKKQLSE-----KQKELEQNNKKI-------KELEKQLN-QLKSEISDLNNQK 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 503 QAKKIEFMKEEIQEVHLDYRQELSRLAEKTKgkedadhlrlTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEK 582
Cdd:TIGR04523 305 EQDWNKELKSELKNQEKKLEEIQNQISQNNK----------IISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEK 374
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 583 ILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQT 662
Cdd:TIGR04523 375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKEL 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 663 KQPKLGRRSTLLstvsEMDTSVYMREAEEVRALEEQRQalmSNLAEKRRQLvDSKKSQSTANTTIVTTTTTEISKSSQSA 742
Cdd:TIGR04523 455 IIKNLDNTRESL----ETQLKVLSRSINKIKQNLEQKQ---KELKSKEKEL-KKLNEEKKELEEKVKDLTKKISSLKEKI 526
|
....*.
gi 17534555 743 SELSNR 748
Cdd:TIGR04523 527 EKLESE 532
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
129-756 |
9.85e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 60.08 E-value: 9.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 129 EKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEEltsfrmEYV---TKLSEANREKK 205
Cdd:TIGR02169 231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEE------EQLrvkEKIGELEAEIA 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 206 ALEEKLEKYKNDMKENDRkslELNKEQVTTQNVLSEVRQLSAHFEfltpvRKNASKIRELDEYHQLsakviEESMNDLKI 285
Cdd:TIGR02169 305 SLERSIAEKERELEDAEE---RLAKLEAEIDKLLAEIEELEREIE-----EERKRRDKLTEEYAEL-----KEELEDLRA 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 286 KNETLTKELSDKTELVKMKNEELEDLrqttTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKLKQELE 365
Cdd:TIGR02169 372 ELEEVDKEFAETRDELKDYREKLEKL----KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 366 KERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMGK------ 439
Cdd:TIGR02169 448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgtv 527
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 440 -HLIMADQQcstFKSLKESAEGSRRRAI--------EQC-----------------NEMVVRIRDLQTSLES-------- 485
Cdd:TIGR02169 528 aQLGSVGER---YATAIEVAAGNRLNNVvveddavaKEAiellkrrkagratflplNKMRDERRDLSILSEDgvigfavd 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 486 ----QRKVEQEV-----EMLKAENSRQAKK--IEF----MKEEIQE--------------VHLDYRQELSRLAEKTKGKE 536
Cdd:TIGR02169 605 lvefDPKYEPAFkyvfgDTLVVEDIEAARRlmGKYrmvtLEGELFEksgamtggsraprgGILFSRSEPAELQRLRERLE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 537 DADHLRLTLSQrdsELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCE 616
Cdd:TIGR02169 685 GLKRELSSLQS---ELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELK 761
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 617 RLERESATKEDKLDKLEEEL--------QEKKQQIAESKELVTYLHSQIDAK-QTKQPKLGRRSTLLSTVSEM--DTSVY 685
Cdd:TIGR02169 762 ELEARIEELEEDLHKLEEALndlearlsHSRIPEIQAELSKLEEEVSRIEARlREIEQKLNRLTLEKEYLEKEiqELQEQ 841
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17534555 686 MREAEEVRALEEQRQALMSNLAEKRRQLVDSKKSQSTANTTIVTTTTTEISKSSQSASELSNRQGTMRHDI 756
Cdd:TIGR02169 842 RIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQI 912
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
258-753 |
1.40e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.77 E-value: 1.40e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 258 NASKIRELDEYHQLSAKVIEESMNDLKIKNETLTKeLSDKTELVKMKN----------EELEDLRQTTTASlgdseqATK 327
Cdd:PTZ00121 1025 NIEKIEELTEYGNNDDVLKEKDIIDEDIDGNHEGK-AEAKAHVGQDEGlkpsykdfdfDAKEDNRADEATE------EAF 1097
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 328 YLHEENMKLTRQKADIRCELLEARRKVEGFDKLK-----QELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQ 402
Cdd:PTZ00121 1098 GKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEearkaEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKK 1177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 403 IEELK--TKMFSFEMIKKDHESAKNELSRTQEKLDQMGKHLIMAD----QQCSTFKSLKESAEGSRRRAIEQCNEMVVRI 476
Cdd:PTZ00121 1178 AEAARkaEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDakkaEAVKKAEEAKKDAEEAKKAEEERNNEEIRKF 1257
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 477 ----------RDLQTSLESQRKVEQ---EVEMLKAENSRQA---KKIEFMKEEIQEVHldYRQELSRLAEKTKGKEDADH 540
Cdd:PTZ00121 1258 eearmahfarRQAAIKAEEARKADElkkAEEKKKADEAKKAeekKKADEAKKKAEEAK--KADEAKKKAEEAKKKADAAK 1335
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 541 LRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLR-----------------KGMADALAKIEE 603
Cdd:PTZ00121 1336 KKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKaeekkkadeakkkaeedKKKADELKKAAA 1415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 604 YKRSWQNSQETCERLER--------ESATKEDKLDKLEEELQ---------------EKKQQIAESKELVTYLHSQIDAK 660
Cdd:PTZ00121 1416 AKKKADEAKKKAEEKKKadeakkkaEEAKKADEAKKKAEEAKkaeeakkkaeeakkaDEAKKKAEEAKKADEAKKKAEEA 1495
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 661 QTKQPKLGRRSTLLSTVSEMDTSVYMREAEEVRALEEQRQALMSNLAEKRRQLVDSKKSQStanttivTTTTTEISKSSQ 740
Cdd:PTZ00121 1496 KKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEE-------LKKAEEKKKAEE 1568
|
570
....*....|...
gi 17534555 741 SASELSNRQGTMR 753
Cdd:PTZ00121 1569 AKKAEEDKNMALR 1581
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
15-710 |
5.11e-08 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 57.75 E-value: 5.11e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 15 KKTPRRRALSPKQKPYSSPFQVIDLNNESHEDlKKRVLDAENIIQDLRSERDAL-HETLVDKAGLNesvIIEQSKRVSTQ 93
Cdd:TIGR00606 330 KLNKERRLLNQEKTELLVEQGRLQLQADRHQE-HIRARDSLIQSLATRLELDGFeRGPFSERQIKN---FHTLVIERQED 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 94 ETRIYRRDVNLLEDDLKHHQSQI-----------RILQNKCSTLEMEKQTLQETIQRAQ------DDKKETETELESSRS 156
Cdd:TIGR00606 406 EAKTAAQLCADLQSKERLKQEQAdeirdekkglgRTIELKKEILEKKQEELKFVIKELQqlegssDRILELDQELRKAER 485
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 157 RLHVLEKelSAKANDIFMVTKDLHDKNEELTSFRMEYVTKLSEANREKKALEE-------KLEKYKNDMKENDRKSLEL- 228
Cdd:TIGR00606 486 ELSKAEK--NSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQmemltkdKMDKDEQIRKIKSRHSDELt 563
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 229 -------NKEQV--TTQNVLSEVRQLSahfEFLTPVRKNASKIRELDEYHQLSAKVIEESMNDLKiknETLTKELSDKTE 299
Cdd:TIGR00606 564 sllgyfpNKKQLedWLHSKSKEINQTR---DRLAKLNKELASLEQNKNHINNELESKEEQLSSYE---DKLFDVCGSQDE 637
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 300 LVKMKN--EELEDLRQTTTASLGDSEQATKYLHEENMK-----------------LTRQKADIRCELLEARRKVEGFDKL 360
Cdd:TIGR00606 638 ESDLERlkEEIEKSSKQRAMLAGATAVYSQFITQLTDEnqsccpvcqrvfqteaeLQEFISDLQSKLRLAPDKLKSTESE 717
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 361 KQELEKERDDALA--------------DVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDhesaKNE 426
Cdd:TIGR00606 718 LKKKEKRRDEMLGlapgrqsiidlkekEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTD----VTI 793
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 427 LSRTQEKLDQMGKHLimaDQQCStfkslkESAEGSRRRAIEQCNEMVvrirdlQTSLESQRKVEQEVEMLKAENSRQAKK 506
Cdd:TIGR00606 794 MERFQMELKDVERKI---AQQAA------KLQGSDLDRTVQQVNQEK------QEKQHELDTVVSKIELNRKLIQDQQEQ 858
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 507 IEFMKEEIQEVHLDYRQELSRLAEKTKGKEDADHLRLTLSQRDSELRSAKKTI---QEVKADNQKVQLMLVEVRQHQEKI 583
Cdd:TIGR00606 859 IQHLKSKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDsplETFLEKDQQEKEELISSKETSNKK 938
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 584 LEENVRLrkgMADALAKIEEYKRSWQNS-QETCERLEREsatKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQT 662
Cdd:TIGR00606 939 AQDKVND---IKEKVKNIHGYMKDIENKiQDGKDDYLKQ---KETELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKI 1012
|
730 740 750 760
....*....|....*....|....*....|....*....|....*...
gi 17534555 663 KQPKLGRRSTLlstvsemdtsvyMREAEEVRALEEQRQALMSNLAEKR 710
Cdd:TIGR00606 1013 QERWLQDNLTL------------RKRENELKEVEEELKQHLKEMGQMQ 1048
|
|
| C1_MgcRacGAP |
cd20821 |
protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and ... |
756-809 |
5.20e-08 |
|
protein kinase C conserved region 1 (C1 domain) found in male germ cell RacGap (MgcRacGAP) and similar proteins; MgcRacGAP, also called Rac GTPase-activating protein 1 (RACGAP1) or protein CYK4, plays an important dual role in cytokinesis: i) it is part of centralspindlin-complex, together with the mitotic kinesin MKLP1, which is critical for the structure of the central spindle by promoting microtuble bundling; and ii) after phosphorylation by aurora B, MgcRacGAP becomes an effective regulator of RhoA and plays an important role in the assembly of the contractile ring and the initiation of cytokinesis. MgcRacGAP-like proteins contain an N-terminal C1 domain, and a C-terminal RhoGAP domain. This model corresponds to the C1 domain. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410371 Cd Length: 55 Bit Score: 50.48 E-value: 5.20e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 17534555 756 IPHKWKAfrHVGVLSMKCSLCFVGISAFAKAKKCSHCDVHVHASCAPRVNNTCG 809
Cdd:cd20821 1 RPHRFVS--KTVIKPETCVVCGKRIKFGKKALKCKDCRVVCHPDCKDKLPLPCV 52
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
133-710 |
7.26e-08 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 57.22 E-value: 7.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 133 LQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELtsfrmeyvtklseanREKKALEEKLE 212
Cdd:PRK01156 188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSAL---------------NELSSLEDMKN 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 213 KYKNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAhfeflTPVRKNASKIReldEYHQLSAKVIeesmnDLKIKNETLTK 292
Cdd:PRK01156 253 RYESEIKTAESDLSMELEKNNYYKELEERHMKIIN-----DPVYKNRNYIN---DYFKYKNDIE-----NKKQILSNIDA 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 293 ELSDKTELVKmKNEELEDlrqtttaslgdseqatkyLHEENMKLTRQKADIRCELLEARRK-------VEGFDKLKQELE 365
Cdd:PRK01156 320 EINKYHAIIK-KLSVLQK------------------DYNDYIKKKSRYDDLNNQILELEGYemdynsyLKSIESLKKKIE 380
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 366 KERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMGKHLImad 445
Cdd:PRK01156 381 EYSKNIERMSAFISEILKIQEIDPDAIKKELNEINVKLQDISSKVSSLNQRIRALRENLDELSRNMEMLNGQSVCPV--- 457
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 446 qqCSTfkslkESAEGSRRRAIEQCNEMVVRIRdlqtslESQRKVEQEVEMLKAENSRQAKKIEFM-KEEIQEVHLDYRQE 524
Cdd:PRK01156 458 --CGT-----TLGEEKSNHIINHYNEKKSRLE------EKIREIEIEVKDIDEKIVDLKKRKEYLeSEEINKSINEYNKI 524
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 525 LSRLAEKTKGKEDADHLR---LTLSQRDSELRSAKKTIQEVKAD---NQKVQLMLVEVRQHQEKILEENVRLRkgmaDAL 598
Cdd:PRK01156 525 ESARADLEDIKIKINELKdkhDKYEEIKNRYKSLKLEDLDSKRTswlNALAVISLIDIETNRSRSNEIKKQLN----DLE 600
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 599 AKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQPklgRRSTLLSTVS 678
Cdd:PRK01156 601 SRLQEIEIGFPDDKSYIDKSIREIENEANNLNNKYNEIQENKILIEKLRGKIDNYKKQIAEIDSIIP---DLKEITSRIN 677
|
570 580 590
....*....|....*....|....*....|..
gi 17534555 679 EMDTsvymreaeEVRALEEQRQALMSNLAEKR 710
Cdd:PRK01156 678 DIED--------NLKKSRKALDDAKANRARLE 701
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
51-658 |
1.08e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 56.52 E-value: 1.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 51 VLDAENIIQdLRSERDALHETLVDKAGLNESviiEQSKRVSTQETRIYRRDVNLLEDDLKHHQSQIRILQNKCSTL--EM 128
Cdd:TIGR00618 296 AAHIKAVTQ-IEQQAQRIHTELQSKMRSRAK---LLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIreIS 371
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 129 EKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDL-----HDKNEELTSFRMEYVTKLSEANRE 203
Cdd:TIGR00618 372 CQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLqgqlaHAKKQQELQQRYAELCAAAITCTA 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 204 KKALEEKLEKYKNDMKENDRKSLELNKEQVTTQnvLSEVRQLSAHF---------EFLTPVRKNASKIRELDEYHQLSAK 274
Cdd:TIGR00618 452 QCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQ--ETRKKAVVLARllelqeepcPLCGSCIHPNPARQDIDNPGPLTRR 529
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 275 V--IEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQTTTAsLGDSEQATKYLHEENMKLTRQKADIRCELLEARR 352
Cdd:TIGR00618 530 MqrGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSI-LTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAED 608
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 353 KVEGfdkLKQELEKERDDALADVQKIREVKRNVERELQSLTSL------MAERDEQIEELKTKMFSFEMIkkdhESAKNE 426
Cdd:TIGR00618 609 MLAC---EQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALhalqltLTQERVREHALSIRVLPKELL----ASRQLA 681
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 427 LSRTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKaensrqakk 506
Cdd:TIGR00618 682 LQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQA--------- 752
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 507 iefmKEEIQEVHLDYRQELSRLaektkgkedadhlrLTLSQRDSELRSAKKTIQEvkadnqkvQLMLVEVRQHQEKILEE 586
Cdd:TIGR00618 753 ----RTVLKARTEAHFNNNEEV--------------TAALQTGAELSHLAAEIQF--------FNRLREEDTHLLKTLEA 806
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17534555 587 NVRlRKGMADALAKIEEYKRSWQNSQETCERLErESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQID 658
Cdd:TIGR00618 807 EIG-QEIPSDEDILNLQCETLVQEEEQFLSRLE-EKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSD 876
|
|
| C1_ScPKC1-like_rpt2 |
cd20823 |
second protein kinase C conserved region 1 (C1 domain) found in Saccharomyces cerevisiae ... |
754-813 |
1.39e-07 |
|
second protein kinase C conserved region 1 (C1 domain) found in Saccharomyces cerevisiae protein kinase C-like 1 (ScPKC1) and similar proteins; ScPKC1 is required for cell growth and for the G2 to M transition of the cell division cycle. It mediates a protein kinase cascade, activating BCK1 which itself activates MKK1/MKK2. The family also includes Schizosaccharomyces pombe PKC1 and PKC2, which are involved in the control of cell shape and act as targets of the inhibitor staurosporine. Members of this family contain two copies of C1 domain. This model corresponds to the second one. The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains; it contains two separate Zn(2+)-binding sites.
Pssm-ID: 410373 Cd Length: 59 Bit Score: 49.61 E-value: 1.39e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17534555 754 HDIPHKWKAFRhvgVLSMK-CSLCFVGIS-AFAKAKKCSHCDVHVHASCAPRVNNTCGMPLQ 813
Cdd:cd20823 1 HRIPHRFEPFT---NLGANwCCHCGQMLPlGRKQIRKCTECGKTAHAQCAHLVPNFCGLSME 59
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
283-703 |
2.14e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.16 E-value: 2.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 283 LKIKNETLTKELSDKTELVKMKNEELEDLRQTTTASLGDSEQATKYLHEenmkLTRQKADIRCELLEARRKVEGFDKLKQ 362
Cdd:COG4717 51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEE----LEEELEELEAELEELREELEKLEKLLQ 126
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 363 elekerddaladVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMG-KHL 441
Cdd:COG4717 127 ------------LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATeEEL 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 442 IMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQ------------------------------ 491
Cdd:COG4717 195 QDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERlkearlllliaaallallglggsllslilt 274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 492 -------EVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSRLAEKtkgKEDADHLRLTLSQRDSELRSAKKTIQEVKA 564
Cdd:COG4717 275 iagvlflVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEEL---EELLAALGLPPDLSPEELLELLDRIEELQE 351
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 565 DNQKV-----QLMLVEVRQHQEKILEE-NVRLRKGMADALAKIEEY---KRSWQNSQETCERLERESATKEDKLDK--LE 633
Cdd:COG4717 352 LLREAeeleeELQLEELEQEIAALLAEaGVEDEEELRAALEQAEEYqelKEELEELEEQLEELLGELEELLEALDEeeLE 431
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 634 EELQEKKQQIAESKELVTYLHSQIDAKQTKQPKLGRRSTLlstvSEMDTSVYMREAeEVRALEEQRQALM 703
Cdd:COG4717 432 EELEELEEELEELEEELEELREELAELEAELEQLEEDGEL----AELLQELEELKA-ELRELAEEWAALK 496
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
474-753 |
2.45e-07 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 55.02 E-value: 2.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 474 VRIRDLQTSLESQRKVEQEVEMLKaenSRqakkiEFMKEEIQEVHLDYRQELSRLAE-----------KTKGKEDADHLR 542
Cdd:COG3206 68 VLLSGLSSLSASDSPLETQIEILK---SR-----PVLERVVDKLNLDEDPLGEEASReaaierlrknlTVEPVKGSNVIE 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 543 LTLSQRDSELrsAKKTIQEVkADN---QKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQetcerLE 619
Cdd:COG3206 140 ISYTSPDPEL--AAAVANAL-AEAyleQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVD-----LS 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 620 RESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQPKLG----------RRSTLLSTVSEMdTSVYMREA 689
Cdd:COG3206 212 EEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLqspviqqlraQLAELEAELAEL-SARYTPNH 290
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17534555 690 EEVRALEEQRQALMSNLAEKRRQLVDSKKSQSTANTTIVTTTTTEISKSSQSASELSNRQGTMR 753
Cdd:COG3206 291 PDVIALRAQIAALRAQLQQEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELR 354
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
288-579 |
3.83e-07 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 54.13 E-value: 3.83e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 288 ETLTKELSDKTELVKMKNEELEDL-------RQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKL 360
Cdd:pfam07888 86 KEELRQSREKHEELEEKYKELSASseelseeKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQ 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 361 KQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQ-------IEELKTKMFSFEMIKKDHESAKNELSRTQEK 433
Cdd:pfam07888 166 RKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRDTQvlqlqdtITTLTQKLTTAHRKEAENEALLEELRSLQER 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 434 LDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSL-ESQRKVEQEVEMLKAENSRQAKKIEFMKE 512
Cdd:pfam07888 246 LNASERKVEGLGEELSSMAAQRDRTQAELHQARLQAAQLTLQLADASLALrEGRARWAQERETLQQSAEADKDRIEKLSA 325
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17534555 513 EIQEVHLDYRQELS-RLAEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQH 579
Cdd:pfam07888 326 ELQRLEERLQEERMeREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEY 393
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
418-671 |
4.81e-07 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 53.61 E-value: 4.81e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 418 KDHESAKNELSRTQEKLDQMGKHLIMADQQcstfkslKESAEGSRRRAIEQCNEMVVRIRDLQTSLesqRKVEQEVEMLK 497
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKE-------EKALLKQLAALERRIAALARRIRALEQEL---AALEAELAELE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 498 AENSRQAKKIEFMKEEIQEVhLDYRQELSRlaektkgkedADHLRLTLSQRDSElrSAKKTIQEVKADNQKVQLMLVEVR 577
Cdd:COG4942 90 KEIAELRAELEAQKEELAEL-LRALYRLGR----------QPPLALLLSPEDFL--DAVRRLQYLKYLAPARREQAEELR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 578 QHQEKIleenVRLRKGMADALAKIEEYKRSWQNSQEtceRLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQI 657
Cdd:COG4942 157 ADLAEL----AALRAELEAERAELEALLAELEEERA---ALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALI 229
|
250
....*....|....
gi 17534555 658 DAKQTKQPKLGRRS 671
Cdd:COG4942 230 ARLEAEAAAAAERT 243
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
93-758 |
4.93e-07 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 54.59 E-value: 4.93e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 93 QETRIYRRDVNLLEDDLKH---HQSQIRILQNKCStlemEKQTLQETIQRAQDDKKETETELESSRSRLHVLEK-----E 164
Cdd:TIGR00618 212 CMPDTYHERKQVLEKELKHlreALQQTQQSHAYLT----QKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEEtqeriN 287
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 165 LSAKANDIFMVTKDLhdknEELTSFRMEYVTKLSEANREkkaLEEKLEKYKNDMKEndrkSLELNKEQVTTQNVLSEVRQ 244
Cdd:TIGR00618 288 RARKAAPLAAHIKAV----TQIEQQAQRIHTELQSKMRS---RAKLLMKRAAHVKQ----QSSIEEQRRLLQTLHSQEIH 356
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 245 LSAHFEFLTPVRKNASKIRELDEYHQLSAKVIE---ESMNDLKIKNETLTKELSDktelVKMKNEELEDLRQTTTASLGD 321
Cdd:TIGR00618 357 IRDAHEVATSIREISCQQHTLTQHIHTLQQQKTtltQKLQSLCKELDILQREQAT----IDTRTSAFRDLQGQLAHAKKQ 432
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 322 SEQATKYLHEENMKLTRQkadIRCELLEARRKVEGFDKLKQELEKERDDALAdVQKIREVKRNVERELQSLTSLMAERDE 401
Cdd:TIGR00618 433 QELQQRYAELCAAAITCT---AQCEKLEKIHLQESAQSLKEREQQLQTKEQI-HLQETRKKAVVLARLLELQEEPCPLCG 508
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 402 QIEELKTKMFSFEMIKKDhesaKNELSRTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQT 481
Cdd:TIGR00618 509 SCIHPNPARQDIDNPGPL----TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKE 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 482 SLESQRKVEQEVEMLKAENSRQAKK------IEFMKEEIQEVHLDYRQELSRLAEKTKGKEDADH-LRLTLSQRDSELRS 554
Cdd:TIGR00618 585 DIPNLQNITVRLQDLTEKLSEAEDMlaceqhALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHaLQLTLTQERVREHA 664
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 555 AKKTIQevkadnqkvQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERE----SATKEDKLD 630
Cdd:TIGR00618 665 LSIRVL---------PKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEienaSSSLGSDLA 735
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 631 KLEEELQEKKQQIAESKElvTYLHSQIDAKQTKQPKLgrrstllsTVSEMDTSVYMREAEEVRALEEQRQALMSNLAEKR 710
Cdd:TIGR00618 736 AREDALNQSLKELMHQAR--TVLKARTEAHFNNNEEV--------TAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLE 805
|
650 660 670 680
....*....|....*....|....*....|....*....|....*...
gi 17534555 711 RQLVDSKKSQSTANTTIVTTTTTEISKSSQSASELSNRQGTMRHDIPH 758
Cdd:TIGR00618 806 AEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLK 853
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
420-721 |
5.09e-07 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 54.36 E-value: 5.09e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 420 HESAKNElSRTQEKLDQMGKHLIMADQQcstfkslKESAEGSRRRAIEQCNemvvriRDLQTSLESQRKVEQEVEMLKAE 499
Cdd:pfam17380 280 HQKAVSE-RQQQEKFEKMEQERLRQEKE-------EKAREVERRRKLEEAE------KARQAEMDRQAAIYAEQERMAME 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 500 NSRQAKKIEfMKEEIQEVHLDYRQELSRLAEKTKGKEDADHLRLTLSQR-DSELRSAKKTIQEVKADNQKVQLMLVE--- 575
Cdd:pfam17380 346 RERELERIR-QEERKRELERIRQEEIAMEISRMRELERLQMERQQKNERvRQELEAARKVKILEEERQRKIQQQKVEmeq 424
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 576 VRQHQEKILEENVR-LRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDK---------------LEEELQEK 639
Cdd:pfam17380 425 IRAEQEEARQREVRrLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKekrdrkraeeqrrkiLEKELEER 504
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 640 KQQIAESKELVTYLHSQIDAKQTK-QPKLGRRSTLLSTVSEMDTSVYMREAEEVRALEEQRQAL--MSNLAEKRRQLVDS 716
Cdd:pfam17380 505 KQAMIEEERKRKLLEKEMEERQKAiYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLeaMEREREMMRQIVES 584
|
....*
gi 17534555 717 KKSQS 721
Cdd:pfam17380 585 EKARA 589
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
110-661 |
1.17e-06 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 53.26 E-value: 1.17e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 110 KHHQSQIRILQNKCSTLEMEKQTLQETIQRAQddkketeTELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNE---EL 186
Cdd:pfam01576 408 KKLEGQLQELQARLSESERQRAELAEKLSKLQ-------SELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQEllqEE 480
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 187 TSFRMEYVTKLSEANREKKALEEKLEKykndmKENDRKSLElnKEQVTTQNVLSEVRQlsahfefltPVRKNASKIRELD 266
Cdd:pfam01576 481 TRQKLNLSTRLRQLEDERNSLQEQLEE-----EEEAKRNVE--RQLSTLQAQLSDMKK---------KLEEDAGTLEALE 544
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 267 EYHQLSAKVIEESMNDLKIKNETLTKELSDKTELvkmkNEELEDL-------RQTTTASLGDSEQATKYLHEENMKLTRQ 339
Cdd:pfam01576 545 EGKKRLQRELEALTQQLEEKAAAYDKLEKTKNRL----QQELDDLlvdldhqRQLVSNLEKKQKKFDQMLAEEKAISARY 620
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 340 KADIRCELLEAR----------RKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTK 409
Cdd:pfam01576 621 AEERDRAEAEAReketralslaRALEEALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQ 700
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 410 MFSFEMIKKDHESAKNELSRTQEKLD-QMGKHLIMADQQcstfkslkesAEGSRRRAIEQCNEMVVRIRDLQT----SLE 484
Cdd:pfam01576 701 LEELEDELQATEDAKLRLEVNMQALKaQFERDLQARDEQ----------GEEKRRQLVKQVRELEAELEDERKqraqAVA 770
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 485 SQRKVEQEVEMLKA----------ENSRQAKKIEF-MKE---EIQEVHLDyRQEL---SRLAEKTKGKEDADHLRLTLSQ 547
Cdd:pfam01576 771 AKKKLELDLKELEAqidaankgreEAVKQLKKLQAqMKDlqrELEEARAS-RDEIlaqSKESEKKLKNLEAELLQLQEDL 849
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 548 RDSElrSAKKTIQ--------EVKADNQKVQLMLVEVRQHQEKI--LEENVRLRKGMADALAkiEEYKRswqnSQETCER 617
Cdd:pfam01576 850 AASE--RARRQAQqerdeladEIASGASGKSALQDEKRRLEARIaqLEEELEEEQSNTELLN--DRLRK----STLQVEQ 921
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 17534555 618 LERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQ 661
Cdd:pfam01576 922 LTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVKSKF 965
|
|
| PLN02939 |
PLN02939 |
transferase, transferring glycosyl groups |
330-625 |
1.38e-06 |
|
transferase, transferring glycosyl groups
Pssm-ID: 215507 [Multi-domain] Cd Length: 977 Bit Score: 52.98 E-value: 1.38e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 330 HEENMKLTRQKADIRCE-LLEARRKVEgfdKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKT 408
Cdd:PLN02939 115 QQTNSKDGEQLSDFQLEdLVGMIQNAE---KNILLLNQARLQALEDLEKILTEKEALQGKINILEMRLSETDARIKLAAQ 191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 409 KMFSFEMIKKDHESAKNELSRTQEKLDQMGKHLIMadqqcsTFKSLKESaEGSRRRAIEQCNEMVVRIRDLQtslESQRK 488
Cdd:PLN02939 192 EKIHVEILEEQLEKLRNELLIRGATEGLCVHSLSK------ELDVLKEE-NMLLKDDIQFLKAELIEVAETE---ERVFK 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 489 VEQEVEMLKAENSRQAKKIEFMKEEI-------QEVHLDYRQELSRLAEKTKGKedADHLRLTLSQRDsELRSAKKTIQE 561
Cdd:PLN02939 262 LEKERSLLDASLRELESKFIVAQEDVsklsplqYDCWWEKVENLQDLLDRATNQ--VEKAALVLDQNQ-DLRDKVDKLEA 338
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17534555 562 V--KADNQKVQLMLVEVRQHQEKILEEnvRLRKGMADALAKIEEYKRSWQNSQETCERLERESATK 625
Cdd:PLN02939 339 SlkEANVSKFSSYKVELLQQKLKLLEE--RLQASDHEIHSYIQLYQESIKEFQDTLSKLKEESKKR 402
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
120-364 |
1.43e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 52.07 E-value: 1.43e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 120 QNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEEltsfrmeyvtkLSE 199
Cdd:COG4942 19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE-----------LAE 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 200 ANREKKALEEKLEKYKNDMKENDRKSLELNKEQ-----VTTQNVLSEVRQLSAhFEFLTPVRKNasKIRELDEYHQLSAK 274
Cdd:COG4942 88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPplallLSPEDFLDAVRRLQY-LKYLAPARRE--QAEELRADLAELAA 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 275 VIEESMNDLKIKNETLTKELSDKTELVKMKNEElEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKV 354
Cdd:COG4942 165 LRAELEAERAELEALLAELEEERAALEALKAER-QKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
|
250
....*....|..
gi 17534555 355 E--GFDKLKQEL 364
Cdd:COG4942 244 PaaGFAALKGKL 255
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
172-646 |
1.60e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 53.13 E-value: 1.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 172 IFMVTKDLHDKNEELTSFRMEYVTK----LSEANREKKAL-----EEKLEKYKNDMKENDRKSLELNKEqvttqnvLSEV 242
Cdd:TIGR01612 498 ILMRMKDFKDIIDFMELYKPDEVPSkniiGFDIDQNIKAKlykeiEAGLKESYELAKNWKKLIHEIKKE-------LEEE 570
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 243 RQLSAHFEfltpvrknaSKIREL-DEYHQLSAKVIeeSMNDLKIKNETLTKELSDKTELVKmKNEELEDLRQTTTASLGD 321
Cdd:TIGR01612 571 NEDSIHLE---------KEIKDLfDKYLEIDDEII--YINKLKLELKEKIKNISDKNEYIK-KAIDLKKIIENNNAYIDE 638
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 322 SEQATKYLHEENMKLTRQ-KADIRCELLEARRkvEGFDKLKQELE---KERD-DALADVQKIREVKRNVERELQSLTSLM 396
Cdd:TIGR01612 639 LAKISPYQVPEHLKNKDKiYSTIKSELSKIYE--DDIDALYNELSsivKENAiDNTEDKAKLDDLKSKIDKEYDKIQNME 716
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 397 AERDE----QIEELKTKMFS--FEMIKKDHESAKNELSRTQEKLDQMGKHLIMADQQCSTFKS----LKESAEGSRRRAI 466
Cdd:TIGR01612 717 TATVElhlsNIENKKNELLDiiVEIKKHIHGEINKDLNKILEDFKNKEKELSNKINDYAKEKDelnkYKSKISEIKNHYN 796
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 467 EQCNEMVVRIRDLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEIqevhLDYRQELSRLAEKTKGKEDADHLRLT-- 544
Cdd:TIGR01612 797 DQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDF----LNKVDKFINFENNCKEKIDSEHEQFAel 872
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 545 LSQRDSELRSAKKTIQEVKADNQKVqlMLVEVRQHQEKILEEnvrlrkgmADALAKIEEYKRSWQNSQETCERLeresat 624
Cdd:TIGR01612 873 TNKIKAEISDDKLNDYEKKFNDSKS--LINEINKSIEEEYQN--------INTLKKVDEYIKICENTKESIEKF------ 936
|
490 500
....*....|....*....|..
gi 17534555 625 kEDKLDKLEEELQEKKQQIAES 646
Cdd:TIGR01612 937 -HNKQNILKEILNKNIDTIKES 957
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
43-706 |
1.67e-06 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 52.52 E-value: 1.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 43 SHEDLKKRVLDAENIIQDLRSERDALH-----ETLVDKAGLNESVIIEQSKRVSTQETRIYRRDVN---LLEDDLKHHQS 114
Cdd:pfam10174 65 TQEENQHLQLTIQALQDELRAQRDLNQllqqdFTTSPVDGEDKFSTPELTEENFRRLQSEHERQAKelfLLRKTLEEMEL 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 115 QIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSR------SRLHVLEKELSAKANDIFMVTKDLHDKNEelts 188
Cdd:pfam10174 145 RIETQKQTLGARDESIKKLLEMLQSKGLPKKSGEEDWERTRriaeaeMQLGHLEVLLDQKEKENIHLREELHRRNQ---- 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 189 frmeyvtkLSEANREKKALEEKLEkykndMKENDRKSLELNK-------EQVTTQNVLS------EVRQLSA---HFEFL 252
Cdd:pfam10174 221 --------LQPDPAKTKALQTVIE-----MKDTKISSLERNIrdledevQMLKTNGLLHtedreeEIKQMEVyksHSKFM 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 253 TpvrknaSKIRELDEyhQLSAKviEESMNDLKIKNETLTKELSDKTELVKMKNEEL--EDLRQTTTASLGDS-------- 322
Cdd:pfam10174 288 K------NKIDQLKQ--ELSKK--ESELLALQTKLETLTNQNSDCKQHIEVLKESLtaKEQRAAILQTEVDAlrlrleek 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 323 ----EQATKYLH---EENMKLTRQKADIRCELLEARRKVEGFDKL---KQELEKERDDALAD----VQKIREVKRNVERE 388
Cdd:pfam10174 358 esflNKKTKQLQdltEEKSTLAGEIRDLKDMLDVKERKINVLQKKienLQEQLRDKDKQLAGlkerVKSLQTDSSNTDTA 437
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 389 LQSLTSLMAERDEQIEELKTKMFSFEMIKKDH-ESAKNELSRTQEKLDQMGKHLImadQQCSTFKSLKESAEGSRRRAIE 467
Cdd:pfam10174 438 LTTLEEALSEKERIIERLKEQREREDRERLEElESLKKENKDLKEKVSALQPELT---EKESSLIDLKEHASSLASSGLK 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 468 QCNemvvRIRDLQTSLESQRK--VEQEVEMLKAENSRQAKKiefMKEEIQEVHLDYRQELSRLAEK-TKGKEDADHLRLT 544
Cdd:pfam10174 515 KDS----KLKSLEIAVEQKKEecSKLENQLKKAHNAEEAVR---TNPEINDRIRLLEQEVARYKEEsGKAQAEVERLLGI 587
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 545 LSQRDSELRSAKKTIQEV-KADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQ--ETCERLERe 621
Cdd:pfam10174 588 LREVENEKNDKDKKIAELeSLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQleELMGALEK- 666
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 622 saTKEdKLDKLEEELQEKKQQIAESKELVTYLHSQiDAKQTKQPKLGRRSTLLSTVSEMDTSVYMRE---------AEEV 692
Cdd:pfam10174 667 --TRQ-ELDATKARLSSTQQSLAEKDGHLTNLRAE-RRKQLEEILEMKQEALLAAISEKDANIALLElssskkkktQEEV 742
|
730
....*....|....
gi 17534555 693 RALEEQRQALMSNL 706
Cdd:pfam10174 743 MALKREKDRLVHQL 756
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
261-721 |
2.53e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 52.28 E-value: 2.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 261 KIRELDEYHQLSAKVIEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQTTTASLGDS--EQATKYLHEENMKLTR 338
Cdd:TIGR00618 195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkkQQLLKQLRARIEELRA 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 339 QKADIRC--ELLEARRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAER---DEQIEELKTKMFSF 413
Cdd:TIGR00618 275 QEAVLEEtqERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQssiEEQRRLLQTLHSQE 354
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 414 EMIKKDHESAKNELSRTQEKLDQMgKHLIMADQQCSTFKSLKESAegSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEV 493
Cdd:TIGR00618 355 IHIRDAHEVATSIREISCQQHTLT-QHIHTLQQQKTTLTQKLQSL--CKELDILQREQATIDTRTSAFRDLQGQLAHAKK 431
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 494 EMlKAENSRQAKKIEFMKEEIQEVHLDYRqELSRLAEKTKGKEdadhlrltlsqrdsELRSAKKTIQEVKADNQKVQLML 573
Cdd:TIGR00618 432 QQ-ELQQRYAELCAAAITCTAQCEKLEKI-HLQESAQSLKERE--------------QQLQTKEQIHLQETRKKAVVLAR 495
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 574 VEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYL 653
Cdd:TIGR00618 496 LLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSIL 575
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17534555 654 HSQIDAKQTKQPKLGRRSTLLSTVSEMDTSVYMREAEEVRALEEQRQalmSNLAEKRRQLVDSKKSQS 721
Cdd:TIGR00618 576 TQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQ---PEQDLQDVRLHLQQCSQE 640
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
554-753 |
2.86e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 2.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 554 SAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLE 633
Cdd:COG4942 17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 634 EELQEKKQQIAEskelvtylhsQIDAKQtkqpKLGRRSTLLSTVSEMDTSVYMREAEEVRALEEQRQALMSNLAEKRRQL 713
Cdd:COG4942 97 AELEAQKEELAE----------LLRALY----RLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL 162
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 17534555 714 VDSKKSQSTANTTIVTTTTTEISKSSQSASELSNRQGTMR 753
Cdd:COG4942 163 AALRAELEAERAELEALLAELEEERAALEALKAERQKLLA 202
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
143-744 |
4.75e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 51.13 E-value: 4.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 143 DKKETETELESSRSRLHVLEKELSAKandiFMVTKDlhDKNEELTSFRMEYVTKLSEANREKKALEEKLEKYKNDMKEND 222
Cdd:pfam02463 152 PERRLEIEEEAAGSRLKRKKKEALKK----LIEETE--NLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 223 RKSLELNKEQVTTQNVLSEVRQL---------------SAHFEFLTPVRKNASKIRELDEYHQLSAKVIEESMNDLKIKN 287
Cdd:pfam02463 226 LLYLDYLKLNEERIDLLQELLRDeqeeiesskqeiekeEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKL 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 288 ETLTKELSDKTELVKMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKLKQELEKE 367
Cdd:pfam02463 306 ERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESER 385
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 368 RDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSF-EMIKKDHESAKNELSRTQEKLDQMGKHLIMADQ 446
Cdd:pfam02463 386 LSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEIlEEEEESIELKQGKLTEEKEELEKQELKLLKDEL 465
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 447 QCSTFKSLKESAE--------------------GSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKAENSRQAKK 506
Cdd:pfam02463 466 ELKKSEDLLKETQlvklqeqlelllsrqkleerSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAI 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 507 IEFMKEEIQEVHLDYRQELSRLAEKTKGKEDADHLRLTLSQRDSELRSAKK-----TIQEVKADNQKVQLMLVEVRQHQE 581
Cdd:pfam02463 546 STAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVleidpILNLAQLDKATLEADEDDKRAKVV 625
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 582 KILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQ 661
Cdd:pfam02463 626 EGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 662 TKQPKLGRRSTLLSTVSE--MDTSVYMREAEEVRALEEQRQALMSNLAEKRRQLVDSKKSQSTANTTIVTTTTTEISKSS 739
Cdd:pfam02463 706 QREKEELKKLKLEAEELLadRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEK 785
|
....*
gi 17534555 740 QSASE 744
Cdd:pfam02463 786 LKVEE 790
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
139-717 |
5.74e-06 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 51.12 E-value: 5.74e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 139 RAQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELTSFRMEYVTKLSEANREKKALEEKLEKYKnDM 218
Cdd:TIGR00618 184 MEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQ-LL 262
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 219 KENDRKSLELNKEQVTTQNvLSEVRQLSAHFEFLTPVRKNASKIReldeyhqlsaKVIEESMNDLKIKNETLTKELSDKT 298
Cdd:TIGR00618 263 KQLRARIEELRAQEAVLEE-TQERINRARKAAPLAAHIKAVTQIE----------QQAQRIHTELQSKMRSRAKLLMKRA 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 299 ELVKMKNEELEDLRqtttaslgdSEQATKYLHEENMKLTRQKADIRCELlearrkvegfdklkqelekerDDALADVQKI 378
Cdd:TIGR00618 332 AHVKQQSSIEEQRR---------LLQTLHSQEIHIRDAHEVATSIREIS---------------------CQQHTLTQHI 381
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 379 REVKRNVERELQSLTSLMAERDEQIEELKTKMFsfemikkdhesaknelsRTQEKLDQMGkHLIMADQQCstfKSLKESA 458
Cdd:TIGR00618 382 HTLQQQKTTLTQKLQSLCKELDILQREQATIDT-----------------RTSAFRDLQG-QLAHAKKQQ---ELQQRYA 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 459 EGSRRRAIEQCNEMVVRIRDLQtslESQRKVEQEVEMLKaensrQAKKIEFMKEEIQEVHLDYRQELSRLAEKTKGKEDA 538
Cdd:TIGR00618 441 ELCAAAITCTAQCEKLEKIHLQ---ESAQSLKEREQQLQ-----TKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIH 512
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 539 DHLRLTLSQRDSEL-RSAKKTIQEVKADNQ---KVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQET 614
Cdd:TIGR00618 513 PNPARQDIDNPGPLtRRMQRGEQTYAQLETseeDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNI 592
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 615 CERLERESATKEDKLDKLEEELQEKKQQIAESKELV-TYLHSQIDAKQTKQPKLGRRSTLLSTVSEMDTSVYMREAEEVR 693
Cdd:TIGR00618 593 TVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQdVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPK 672
|
570 580
....*....|....*....|....
gi 17534555 694 ALEEQRQALMSNLAEKRRQLVDSK 717
Cdd:TIGR00618 673 ELLASRQLALQKMQSEKEQLTYWK 696
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
263-709 |
6.33e-06 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 50.54 E-value: 6.33e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 263 RELDEYHQLSAKVIEESMNDLKIKNETLtKELSDKTELVKMKNEELEDLRQtttaSLGDSEQATKYLHEENMKLTRQKA- 341
Cdd:COG4717 53 KEADELFKPQGRKPELNLKELKELEEEL-KEAEEKEEEYAELQEELEELEE----ELEELEAELEELREELEKLEKLLQl 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 342 -DIRCELLEARRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIE-ELKTKMFSFEMIKKD 419
Cdd:COG4717 128 lPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEeELQDLAEELEELQQR 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 420 HESAKNELSRTQEKLDQmgkhlimADQQCSTFKSLKESAEGSRRraIEQcNEMVVRIRDLQTSLESQRKVEQEVEMLKAE 499
Cdd:COG4717 208 LAELEEELEEAQEELEE-------LEEELEQLENELEAAALEER--LKE-ARLLLLIAAALLALLGLGGSLLSLILTIAG 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 500 ------------NSRQAKKIEFMKEEIQEVHLDYRQELSRLAEKtkgKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQ 567
Cdd:COG4717 278 vlflvlgllallFLLLAREKASLGKEAEELQALPALEELEEEEL---EELLAALGLPPDLSPEELLELLDRIEELQELLR 354
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 568 KV-----QLMLVEVRQHQEKIL------------------EENVRLRKGMADALAKIEEYKRSWQNSQETC--------- 615
Cdd:COG4717 355 EAeeleeELQLEELEQEIAALLaeagvedeeelraaleqaEEYQELKEELEELEEQLEELLGELEELLEALdeeeleeel 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 616 ERLERESATKEDKLDKLEEELQEKKQQI--AESKELVTYLHSQIDAKQTKQPKLGRRSTLLSTVSEMdtsvyMREAEEvr 693
Cdd:COG4717 435 EELEEELEELEEELEELREELAELEAELeqLEEDGELAELLQELEELKAELRELAEEWAALKLALEL-----LEEARE-- 507
|
490
....*....|....*.
gi 17534555 694 ALEEQRQALMSNLAEK 709
Cdd:COG4717 508 EYREERLPPVLERASE 523
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
200-442 |
6.90e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.76 E-value: 6.90e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 200 ANREKKALEEKLEKYKNDMKENDRkslELNKEQVTTQNVLSEVRQLSAHfefltpVRKNASKIRELDEyhqlSAKVIEES 279
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEK---ELAALKKEEKALLKQLAALERR------IAALARRIRALEQ----ELAALEAE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 280 MNDLKIKNETLTKELSDKTELVKmkneelEDLRqtTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRK-VEGFD 358
Cdd:COG4942 85 LAELEKEIAELRAELEAQKEELA------ELLR--ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREqAEELR 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 359 KLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKmfsfemiKKDHESAKNELSRTQEKLDQMG 438
Cdd:COG4942 157 ADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKE-------LAELAAELAELQQEAEELEALI 229
|
....
gi 17534555 439 KHLI 442
Cdd:COG4942 230 ARLE 233
|
|
| PH |
pfam00169 |
PH domain; PH stands for pleckstrin homology. |
835-940 |
8.05e-06 |
|
PH domain; PH stands for pleckstrin homology.
Pssm-ID: 459697 [Multi-domain] Cd Length: 105 Bit Score: 46.02 E-value: 8.05e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 835 MNGWLRVYRDDmTGSTWIASWAMMDLTRISFYTNDGAD-LEKPFFSIDLNKEQWVlrtgqemPVDCDDSMRANNVLMIKM 913
Cdd:pfam00169 3 KEGWLLKKGGG-KKKSWKKRYFVLFDGSLLYYKDDKSGkSKEPKGSISLSGCEVV-------EVVASDSPKRKFCFELRT 74
|
90 100 110
....*....|....*....|....*....|.
gi 17534555 914 ----PRRCLYILAPSQPSARRWAECLQTAQR 940
Cdd:pfam00169 75 gertGKRTYLLQAESEEERKDWIKAIQSAIR 105
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
34-289 |
9.84e-06 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 49.93 E-value: 9.84e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 34 FQVIDLN----NESHEDLKKRVLDAENIIQDLRSerdalhetLVDKAGLNESVIIEQSKRVSTQETRIYRRDVNLLEDDL 109
Cdd:PRK05771 31 VHIEDLKeelsNERLRKLRSLLTKLSEALDKLRS--------YLPKLNPLREEKKKVSVKSLEELIKDVEEELEKIEKEI 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 110 KHHQSQIRILQNKCSTLEMEKQTLQ------ETIQRAQDDK---------KETETELESSRSRLHVLEKELSAKANDIFM 174
Cdd:PRK05771 103 KELEEEISELENEIKELEQEIERLEpwgnfdLDLSLLLGFKyvsvfvgtvPEDKLEELKLESDVENVEYISTDKGYVYVV 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 175 VT---KDLHDKNEELTSFRME----------------YVTKLSEANREKKALEEKLEKYKNdmkendrkslELNKEQVTT 235
Cdd:PRK05771 183 VVvlkELSDEVEEELKKLGFErleleeegtpselireIKEELEEIEKERESLLEELKELAK----------KYLEELLAL 252
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 17534555 236 QNVLSEVRQlsaHFEFLtpvrknaSKIRELDEYHQLSAKVIEESMNDLK--IKNET 289
Cdd:PRK05771 253 YEYLEIELE---RAEAL-------SKFLKTDKTFAIEGWVPEDRVKKLKelIDKAT 298
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
140-391 |
1.02e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 49.38 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 140 AQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEeltsfrmeyvtKLSEANREKKALEEKLEKYKNDMK 219
Cdd:COG4942 18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER-----------RIAALARRIRALEQELAALEAELA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 220 ENDRKSLELNKEQVTTQNVLSEvrQLSAHFefltpVRKNASKIRELdeyhqLSAKVIEESMNDLKIKNEtLTKELSDKTE 299
Cdd:COG4942 87 ELEKEIAELRAELEAQKEELAE--LLRALY-----RLGRQPPLALL-----LSPEDFLDAVRRLQYLKY-LAPARREQAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 300 LVKMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFDKLKQELEKERDDALADVQKIR 379
Cdd:COG4942 154 ELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLE 233
|
250
....*....|..
gi 17534555 380 EVKRNVERELQS 391
Cdd:COG4942 234 AEAAAAAERTPA 245
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
358-568 |
1.31e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 49.06 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 358 DKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMfsfEMIKKDHESAKNELSRTQEKLDQM 437
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEI---DKLQAEIAEAEAEIEERREELGER 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 438 GKHLIMADQQCSTFKSLKESAE--------GSRRRAIEQCNEMVVRIRDLQTSLESQRKveqEVEMLKAENSRQAKKIEF 509
Cdd:COG3883 92 ARALYRSGGSVSYLDVLLGSESfsdfldrlSALSKIADADADLLEELKADKAELEAKKA---ELEAKLAELEALKAELEA 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 17534555 510 MKEEIQEVHLDYRQELSRLAEKTKGKEDAdhLRLTLSQRDSELRSAKKTIQEVKADNQK 568
Cdd:COG3883 169 AKAELEAQQAEQEALLAQLSAEEAAAEAQ--LAELEAELAAAEAAAAAAAAAAAAAAAA 225
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
350-638 |
1.36e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 49.53 E-value: 1.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 350 ARRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIeelktkmfsfemikkDHESAKNELSR 429
Cdd:COG4913 608 NRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEI---------------DVASAEREIAE 672
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 430 TQEKLDQMGK---HLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKAENSRQ--- 503
Cdd:COG4913 673 LEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRAlle 752
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 504 AKKIEFMKEEI-QEVHLDYRQELSRLAEKTKGKEDAdhLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHqek 582
Cdd:COG4913 753 ERFAAALGDAVeRELRENLEERIDALRARLNRAEEE--LERAMRAFNREWPAETADLDADLESLPEYLALLDRLEED--- 827
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 17534555 583 ileenvrlrkGMADALAKIEEYKRSWQNSQET--CERLERESATKEDKLDKLEEELQE 638
Cdd:COG4913 828 ----------GLPEYEERFKELLNENSIEFVAdlLSKLRRAIREIKERIDPLNDSLKR 875
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
421-753 |
1.79e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 1.79e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 421 ESAKNELSRTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRR-RAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKAE 499
Cdd:TIGR02169 173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQAlLKEKREYEGYELLKEKEALERQKEAIERQLASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 500 NSRQAKKIEFMKEEIQEVhldyRQELSRLAEKTKGKEDADHLRLtlsqrdselrsaKKTIQEVKADNQKVQLMLVEVRQH 579
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEI----EQLLEELNKKIKDLGEEEQLRV------------KEKIGELEAEIASLERSIAEKERE 316
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 580 QEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDA 659
Cdd:TIGR02169 317 LEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 660 -KQTKQPKLGRRSTLLSTVSEMDTSVYMREAE------EVRALEEQRQALMSNLAEKRRQL------VDSKKSQSTANTT 726
Cdd:TIGR02169 397 lKREINELKRELDRLQEELQRLSEELADLNAAiagieaKINELEEEKEDKALEIKKQEWKLeqlaadLSKYEQELYDLKE 476
|
330 340
....*....|....*....|....*..
gi 17534555 727 IVTTTTTEISKSSQSASELSNRQGTMR 753
Cdd:TIGR02169 477 EYDRVEKELSKLQRELAEAEAQARASE 503
|
|
| C1_1 |
pfam00130 |
Phorbol esters/diacylglycerol binding domain (C1 domain); This domain is also known as the ... |
758-810 |
1.91e-05 |
|
Phorbol esters/diacylglycerol binding domain (C1 domain); This domain is also known as the Protein kinase C conserved region 1 (C1) domain.
Pssm-ID: 395079 Cd Length: 53 Bit Score: 43.20 E-value: 1.91e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 17534555 758 HKWKA--FRHvgvlSMKCSLCFVGISAFAK-AKKCSHCDVHVHASCAPRVNNTCGM 810
Cdd:pfam00130 1 HHFVHrnFKQ----PTFCDHCGEFLWGLGKqGLKCSWCKLNVHKRCHEKVPPECGC 52
|
|
| PH |
smart00233 |
Pleckstrin homology domain; Domain commonly found in eukaryotic signalling proteins. The ... |
835-940 |
2.32e-05 |
|
Pleckstrin homology domain; Domain commonly found in eukaryotic signalling proteins. The domain family possesses multiple functions including the abilities to bind inositol phosphates, and various proteins. PH domains have been found to possess inserted domains (such as in PLC gamma, syntrophins) and to be inserted within other domains. Mutations in Brutons tyrosine kinase (Btk) within its PH domain cause X-linked agammaglobulinaemia (XLA) in patients. Point mutations cluster into the positively charged end of the molecule around the predicted binding site for phosphatidylinositol lipids.
Pssm-ID: 214574 [Multi-domain] Cd Length: 102 Bit Score: 44.46 E-value: 2.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 835 MNGWLRVYRDDMTGStWIASWAMMDLTRISFYTNDGADLE-KPFFSIDLNKEQWVlrtgqemPVDCDDSMRANNVLMIKM 913
Cdd:smart00233 3 KEGWLYKKSGGGKKS-WKKRYFVLFNSTLLYYKSKKDKKSyKPKGSIDLSGCTVR-------EAPDPDSSKKPHCFEIKT 74
|
90 100
....*....|....*....|....*...
gi 17534555 914 PRRCLYIL-APSQPSARRWAECLQTAQR 940
Cdd:smart00233 75 SDRKTLLLqAESEEEREKWVEALRKAIA 102
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
233-536 |
3.21e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 48.20 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 233 VTTQNVLSEvRQLSAHFEFLTPVR---KNASKIRELDEYHQL--SAKVIEESMND---LKIKNETLTKELSDKTELVKM- 303
Cdd:pfam17380 278 VQHQKAVSE-RQQQEKFEKMEQERlrqEKEEKAREVERRRKLeeAEKARQAEMDRqaaIYAEQERMAMERERELERIRQe 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 304 -KNEELEDLRQTTTASlgdseQATKYLHEENMKLTRQKADIRC-ELLEARRKVEGFDKLKQELEKERDDALADVQKIREV 381
Cdd:pfam17380 357 eRKRELERIRQEEIAM-----EISRMRELERLQMERQQKNERVrQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEE 431
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 382 KRNVE---------RELQSLTSLMAERDEQIEELKtkmfsfemiKKDHESAKNELSRTQEKLDQMgkhliMADQQcsTFK 452
Cdd:pfam17380 432 ARQREvrrleeeraREMERVRLEEQERQQQVERLR---------QQEEERKRKKLELEKEKRDRK-----RAEEQ--RRK 495
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 453 SLKESAEGSRRRAIEQCNEMVVRIRDLQtslESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSRLAEKT 532
Cdd:pfam17380 496 ILEKELEERKQAMIEEERKRKLLEKEME---ERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEAME 572
|
....
gi 17534555 533 KGKE 536
Cdd:pfam17380 573 RERE 576
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
349-603 |
3.99e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 3.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 349 EARRKVEGFDKLK---QELEKERD--DALADVQKIREvkrnverELQSLtslmAERDEQIEELKTkMFSFEMIKKDHESA 423
Cdd:COG4913 226 AADALVEHFDDLErahEALEDAREqiELLEPIRELAE-------RYAAA----RERLAELEYLRA-ALRLWFAQRRLELL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 424 KNELSRTQEKLDQmgkhlimADQQCSTFKSLKESAEGSRRRAIEQCNEM-VVRIRDLQTSLESQRKVEQEVEMLKAENSR 502
Cdd:COG4913 294 EAELEELRAELAR-------LEAELERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEA 366
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 503 QAKKIEFMKEEIQEVHLDYRQELSRLAEKTKGKEDAdhLRLTLSQRDSELRSAKKTIQEVKADnqkvqlmLVEVRQHQEK 582
Cdd:COG4913 367 LLAALGLPLPASAEEFAALRAEAAALLEALEEELEA--LEEALAEAEAALRDLRRELRELEAE-------IASLERRKSN 437
|
250 260
....*....|....*....|.
gi 17534555 583 ILEENVRLRKGMADALAKIEE 603
Cdd:COG4913 438 IPARLLALRDALAEALGLDEA 458
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
87-672 |
4.64e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.91 E-value: 4.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 87 SKRVSTQETRIYRRDVNLLEDdLKHHQSQIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESsrsrlhvlEKELS 166
Cdd:pfam12128 215 KSRLNRQQVEHWIRDIQAIAG-IMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEE--------RQETS 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 167 AkandifmvtkdlhDKNEELTSFRMEYVTKLSEANREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQ--------NV 238
Cdd:pfam12128 286 A-------------ELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAaadqeqlpSW 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 239 LSEVRQLSAHFEFLTpvrKNASKIREldEYHQLSAKVIEESMNDLKIKNETLTKElsdKTELVKMKNEELEDLRQTTTAS 318
Cdd:pfam12128 353 QSELENLEERLKALT---GKHQDVTA--KYNRRRSKIKEQNNRDIAGIKDKLAKI---REARDRQLAVAEDDLQALESEL 424
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 319 LGDSEQATKYLHEE---------NMKLTRQKADIRCELLEARR-KVEGFDKLKQELE---KERDDALADVQKIREVKRNV 385
Cdd:pfam12128 425 REQLEAGKLEFNEEeyrlksrlgELKLRLNQATATPELLLQLEnFDERIERAREEQEaanAEVERLQSELRQARKRRDQA 504
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 386 ERELQSLTSLMAERDEQIEELKTKMFS-----FEMIKKDHESAKNELSR--TQEKLDQMGKHLIMADQQCS---TFKSLK 455
Cdd:pfam12128 505 SEALRQASRRLEERQSALDELELQLFPqagtlLHFLRKEAPDWEQSIGKviSPELLHRTDLDPEVWDGSVGgelNLYGVK 584
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 456 ESAEGSRRRAIEQCNEMVVRIRD-----LQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVHLDYRqelsrlae 530
Cdd:pfam12128 585 LDLKRIDVPEWAASEEELRERLDkaeeaLQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLR-------- 656
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 531 ktkgkedadhlRLTLSQRDSELRSAKKTIQEVKADNQKVQLMlvevrQHQEKILEenvrlrKGMADALAKIEEYKRswQN 610
Cdd:pfam12128 657 -----------RLFDEKQSEKDKKNKALAERKDSANERLNSL-----EAQLKQLD------KKHQAWLEEQKEQKR--EA 712
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17534555 611 SQETCERLERESATKEDKLDKLEEEL-QEKKQQIAESKELVTYLHSQIDAKQTKQPKLGRRST 672
Cdd:pfam12128 713 RTEKQAYWQVVEGALDAQLALLKAAIaARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKR 775
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
89-643 |
6.30e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 47.53 E-value: 6.30e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 89 RVSTQETRIYRrdVNLLEDDLKHHQSQIRILQNKCSTLEMEKQT--------LQETIQRAQDDKKETETELESSRSRLHV 160
Cdd:pfam12128 249 EFNTLESAELR--LSHLHFGYKSDETLIASRQEERQETSAELNQllrtlddqWKEKRDELNGELSAADAAVAKDRSELEA 326
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 161 LEKELSAKANDifmVTKDLHDKNEELTSFRMEyvtkLSEANREKKAL-------EEKLEKYKNDMKENDRKSLELNKEQV 233
Cdd:pfam12128 327 LEDQHGAFLDA---DIETAAADQEQLPSWQSE----LENLEERLKALtgkhqdvTAKYNRRRSKIKEQNNRDIAGIKDKL 399
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 234 TTQNVlSEVRQL---SAHFEFL-TPVR-KNASKIRELDEYHQLSAKVIEES---MNDLKIKNETLTKELSDKTELVKMK- 304
Cdd:pfam12128 400 AKIRE-ARDRQLavaEDDLQALeSELReQLEAGKLEFNEEEYRLKSRLGELklrLNQATATPELLLQLENFDERIERARe 478
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 305 -----NEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKAdiRCELLEArrkvEGFDKLKQELEKERDDALADVQKIR 379
Cdd:pfam12128 479 eqeaaNAEVERLQSELRQARKRRDQASEALRQASRRLEERQS--ALDELEL----QLFPQAGTLLHFLRKEAPDWEQSIG 552
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 380 EVkrnVERELQSLTSLMAERDE----------------QIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMGKHLIM 443
Cdd:pfam12128 553 KV---ISPELLHRTDLDPEVWDgsvggelnlygvkldlKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQ 629
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 444 ADQQCSTFKSLKESA----EGSRRRAIEQCNEMVVRIRDLQTSLES-QRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVH 518
Cdd:pfam12128 630 ANGELEKASREETFArtalKNARLDLRRLFDEKQSEKDKKNKALAErKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQK 709
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 519 LDYRQELSRLAEKTKGKEDA--DHLRLTLSQRDSELRSAKKTIQEVKA--------DNQKVQLMLVEVRQHQEKIleENV 588
Cdd:pfam12128 710 REARTEKQAYWQVVEGALDAqlALLKAAIAARRSGAKAELKALETWYKrdlaslgvDPDVIAKLKREIRTLERKI--ERI 787
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17534555 589 RLRKgmadalAKIEEYKRsWQNSQ---------ETCERLERESATKEDKLDKLEEELQEKKQQI 643
Cdd:pfam12128 788 AVRR------QEVLRYFD-WYQETwlqrrprlaTQLSNIERAISELQQQLARLIADTKLRRAKL 844
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
59-433 |
6.85e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.44 E-value: 6.85e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 59 QDLRSERDALHETLVDKAGLNESVIIEQSKRvsTQETRIYRRDVNLLEDDLKH-HQSQIRILQNKCSTLEMEKQTLQETI 137
Cdd:PTZ00121 1584 EEAKKAEEARIEEVMKLYEEEKKMKAEEAKK--AEEAKIKAEELKKAEEEKKKvEQLKKKEAEEKKKAEELKKAEEENKI 1661
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 138 QRAQDDKKETETELESSRSRLhvlEKELSAKANDIFMVTKDLHDKNEELTSFRMEYVTKLSEANREKKALEEKLEKYKND 217
Cdd:PTZ00121 1662 KAAEEAKKAEEDKKKAEEAKK---AEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE 1738
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 218 MKENDRKSLELNKEQVTTQNVLSEVRQLSAHFEFLTPVRKNASKiRELDEYHQLSAKVIEESMNDLKiKNETLTKELSDK 297
Cdd:PTZ00121 1739 AEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE-EELDEEDEKRRMEVDKKIKDIF-DNFANIIEGGKE 1816
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 298 TELVKMKNEELEDlrqTTTASLGDSEQATKylhEENMKLTRQKADIRCELLEARRKVEGFDKLKQELEkerdDALADVQK 377
Cdd:PTZ00121 1817 GNLVINDSKEMED---SAIKEVADSKNMQL---EEADAFEKHKFNKNNENGEDGNKEADFNKEKDLKE----DDEEEIEE 1886
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 17534555 378 IREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEK 433
Cdd:PTZ00121 1887 ADEIEKIDKDDIEREIPNNNMAGKNNDIIDDKLDKDEYIKRDAEETREEIIKISKK 1942
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
484-674 |
7.05e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.68 E-value: 7.05e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 484 ESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVhLDYRQELSRLAEKTKGKEDAdhLRLTLSQRDSELRSAKKTIQEVK 563
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKAL-LKQLAALERRIAALARRIRA--LEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 564 ADNQKVQLMLVEV--------RQ-------HQEKILEENVRLR--KGMADALAK-IEEYKRSWQNSQETCERLERESATK 625
Cdd:COG4942 97 AELEAQKEELAELlralyrlgRQpplalllSPEDFLDAVRRLQylKYLAPARREqAEELRADLAELAALRAELEAERAEL 176
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 17534555 626 EDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQPKLGRRSTLL 674
Cdd:COG4942 177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEEL 225
|
|
| MAD |
pfam05557 |
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ... |
85-609 |
1.01e-04 |
|
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.
Pssm-ID: 461677 [Multi-domain] Cd Length: 660 Bit Score: 46.66 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 85 EQSKRVSTQETRIYRRDVNLLEDDLKHHQSQIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKE 164
Cdd:pfam05557 68 EEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAK 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 165 LSakandifmvtkDLHDKNEELTSFRMEyvtkLSEANREKKALEEKLEKYKNDmKENDRKSlelNKEQVTTQNVLSEVRQ 244
Cdd:pfam05557 148 AS-----------EAEQLRQNLEKQQSS----LAEAEQRIKELEFEIQSQEQD-SEIVKNS---KSELARIPELEKELER 208
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 245 LSAHFEFLTPVRKNASKIREldEYHQLSAKV-----IEESMNDLKIKNETLTKELsdktelvkmknEELEDLRQTTTASL 319
Cdd:pfam05557 209 LREHNKHLNENIENKLLLKE--EVEDLKRKLereekYREEAATLELEKEKLEQEL-----------QSWVKLAQDTGLNL 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 320 GDSEQAT---KYLHEENMKLTRQKADIRCELLEARRKV-EGFDKLKQELEKerddaLADVQKIREVKRNVERELQSLTSL 395
Cdd:pfam05557 276 RSPEDLSrriEQLQQREIVLKEENSSLTSSARQLEKARrELEQELAQYLKK-----IEDLNKKLKRHKALVRRLQRRVLL 350
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 396 MA-ERDEQIEELKTkmFSFEMIKKDHESAKNELSRTQEKL-DQMGKHLIMADQQCSTfksLKESAEGSRRRAieQCNEMV 473
Cdd:pfam05557 351 LTkERDGYRAILES--YDKELTMSNYSPQLLERIEEAEDMtQKMQAHNEEMEAQLSV---AEEELGGYKQQA--QTLERE 423
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 474 VRIRDLQTSLESQR-------KVEQEVEMLKAENSRQAKKIEFMKEEIQevhldyRQELSRLAEKTKGKedADHLRLTLS 546
Cdd:pfam05557 424 LQALRQQESLADPSyskeevdSLRRKLETLELERQRLREQKNELEMELE------RRCLQGDYDPKKTK--VLHLSMNPA 495
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17534555 547 -----QRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVR----LRKGMADALAKIEEYKRSWQ 609
Cdd:pfam05557 496 aeayqQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFKevldLRKELESAELKNQRLKEVFQ 567
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
101-245 |
1.02e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 46.36 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 101 DVNLLEDDLKHHQSQIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIFMvTKDLH 180
Cdd:COG3883 24 ELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR-SGGSV 102
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17534555 181 DKNEEL---TSF-----RMEYVTKLSEANRekkaleEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVRQL 245
Cdd:COG3883 103 SYLDVLlgsESFsdfldRLSALSKIADADA------DLLEELKADKAELEAKKAELEAKLAELEALKAELEAA 169
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
131-588 |
1.64e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 45.91 E-value: 1.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 131 QTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAkandiFMVTKDLHDKNEELTSFRMEYvtklseanrekKALEEK 210
Cdd:COG4717 91 AELQEELEELEEELEELEAELEELREELEKLEKLLQL-----LPLYQELEALEAELAELPERL-----------EELEER 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 211 LEKYKNDMKENDrkslELNKEQVTTQNVLSEVRQLSAhFEFLTPVRKNASKIRELDEYHQLsakvIEESMNDLKIKNETL 290
Cdd:COG4717 155 LEELRELEEELE----ELEAELAELQEELEELLEQLS-LATEEELQDLAEELEELQQRLAE----LEEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 291 TKELsDKTELVKMKNEELEDLRQTTTASLGDSEQAT-KYLHEENMKLTRQKADIRCELLEARRKVEGFDKLKQELEKERD 369
Cdd:COG4717 226 EEEL-EQLENELEAAALEERLKEARLLLLIAAALLAlLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEA 304
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 370 DALADVQKIREVKrnvERELQS-LTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMGKHLIMADQQC 448
Cdd:COG4717 305 EELQALPALEELE---EEELEElLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGV 381
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 449 STFKSLKESAEgsrrrAIEQCNEMVVRIRDLQTSLESQRKVEQEV------EMLKAENSRQAKKIEFMKEEIQEVHldyr 522
Cdd:COG4717 382 EDEEELRAALE-----QAEEYQELKEELEELEEQLEELLGELEELlealdeEELEEELEELEEELEELEEELEELR---- 452
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17534555 523 QELSRLAEKTKGKEDADhlrlTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENV 588
Cdd:COG4717 453 EELAELEAELEQLEEDG----ELAELLQELEELKAELRELAEEWAALKLALELLEEAREEYREERL 514
|
|
| C1 |
cd00029 |
protein kinase C conserved region 1 (C1 domain) superfamily; The C1 domain is a cysteine-rich ... |
758-808 |
2.01e-04 |
|
protein kinase C conserved region 1 (C1 domain) superfamily; The C1 domain is a cysteine-rich zinc binding domain that does not bind DNA nor possess structural similarity to conventional zinc finger domains. It contains the motif HX12CX2CXnCX2CX4HX2CX7C, where C and H are cysteine and histidine, respectively; X represents other residues; and n is either 13 or 14. C1 has a globular fold with two separate Zn(2+)-binding sites. It was originally discovered as lipid-binding modules in protein kinase C (PKC) isoforms. C1 domains that bind and respond to phorbol esters (PE) and diacylglycerol (DAG) are referred to as typical, and those that do not respond to PE and DAG are deemed atypical. A C1 domain may also be referred to as PKC or non-PKC C1, based on the parent protein's activity. Most C1 domain-containing non-PKC proteins act as lipid kinases and scaffolds, except PKD which acts as a protein kinase. PKC C1 domains play roles in membrane translocation and activation of the enzyme.
Pssm-ID: 410341 Cd Length: 50 Bit Score: 40.19 E-value: 2.01e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 17534555 758 HKWKafRHVGVLSMKCSLCFVGISAFAK-AKKCSHCDVHVHASCAPRVNNTC 808
Cdd:cd00029 1 HRFV--PTTFSSPTFCDVCGKLIWGLFKqGLKCSDCGLVCHKKCLDKAPSPC 50
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
549-719 |
2.10e-04 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 45.21 E-value: 2.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 549 DSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEEnvrlrkgMADALAKIEEykrswqnSQETCERLERESATKEDK 628
Cdd:COG3883 15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEE-------YNELQAELEA-------LQAEIDKLQAEIAEAEAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 629 LDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQpkLGRRSTLLSTVSEMDTSV---YMREAEEVRALEEQRQALMSN 705
Cdd:COG3883 81 IEERREELGERARALYRSGGSVSYLDVLLGSESFSD--FLDRLSALSKIADADADLleeLKADKAELEAKKAELEAKLAE 158
|
170
....*....|....
gi 17534555 706 LAEKRRQLVDSKKS 719
Cdd:COG3883 159 LEALKAELEAAKAE 172
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
543-720 |
2.20e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.14 E-value: 2.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 543 LTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERES 622
Cdd:COG4942 13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 623 ATKEDKLDKLEEELQE--KKQQIAESKELVTYLHSQIDAKQtkqpkLGRRSTLLSTVSEMDtsvyMREAEEVRALEEQRQ 700
Cdd:COG4942 93 AELRAELEAQKEELAEllRALYRLGRQPPLALLLSPEDFLD-----AVRRLQYLKYLAPAR----REQAEELRADLAELA 163
|
170 180
....*....|....*....|
gi 17534555 701 ALMSNLAEKRRQLVDSKKSQ 720
Cdd:COG4942 164 ALRAELEAERAELEALLAEL 183
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
306-516 |
3.40e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.29 E-value: 3.40e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 306 EELEDLRQTTTASLGDSEQATKY--LHEENMKLTRQKADIRceLLEARRKVEGFDKLKQELEKERDDALADVQKIREVKR 383
Cdd:COG4913 242 EALEDAREQIELLEPIRELAERYaaARERLAELEYLRAALR--LWFAQRRLELLEAELEELRAELARLEAELERLEARLD 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 384 NVERELQSLTSLMAERD-EQIEELKTKMfsfEMIKKDHESAKNELSRTQEKLDQMGKHL-----IMADQQcSTFKSLKES 457
Cdd:COG4913 320 ALREELDELEAQIRGNGgDRLEQLEREI---ERLERELEERERRRARLEALLAALGLPLpasaeEFAALR-AEAAALLEA 395
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 17534555 458 AEGSRRRAIEQCNEMVVRIRDLQtslESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQE 516
Cdd:COG4913 396 LEEELEALEEALAEAEAALRDLR---RELRELEAEIASLERRKSNIPARLLALRDALAE 451
|
|
| growth_prot_Scy |
NF041483 |
polarized growth protein Scy; |
130-694 |
3.43e-04 |
|
polarized growth protein Scy;
Pssm-ID: 469371 [Multi-domain] Cd Length: 1293 Bit Score: 45.20 E-value: 3.43e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 130 KQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIfmvTKDLHDKNEELT-----------SFRMEYVTK-- 196
Cdd:NF041483 385 KATTRAAAEEAERIRREAEAEADRLRGEAADQAEQLKGAAKDD---TKEYRAKTVELQeearrlrgeaeQLRAEAVAEge 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 197 --LSEANRE--------KKALEEKLEKYKNDMKENdRKSLELNKEQVTTQNVlsevrqlsahfEFLTPVRKNASKI--RE 264
Cdd:NF041483 462 riRGEARREavqqieeaARTAEELLTKAKADADEL-RSTATAESERVRTEAI-----------ERATTLRRQAEETleRT 529
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 265 LDEYHQLSAKvIEESMNDLKIKNETLTKELSDKTELVKMKN-----EELEDLRQTTTASLGDSEQATKYLHEENMKLTRQ 339
Cdd:NF041483 530 RAEAERLRAE-AEEQAEEVRAAAERAARELREETERAIAARqaeaaEELTRLHTEAEERLTAAEEALADARAEAERIRRE 608
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 340 KAD----IRCELLEARRKVEGfdKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAER---DEQIEELKTKMFS 412
Cdd:NF041483 609 AAEeterLRTEAAERIRTLQA--QAEQEAERLRTEAAADASAARAEGENVAVRLRSEAAAEAERlksEAQESADRVRAEA 686
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 413 FEMIKKDHESAKNELSRTQEKLDQMGKHlimADQqcsTFKSLKESAEGSRRRAIEQCNEM--VVRIRDLQTSLESQRKVE 490
Cdd:NF041483 687 AAAAERVGTEAAEALAAAQEEAARRRRE---AEE---TLGSARAEADQERERAREQSEELlaSARKRVEEAQAEAQRLVE 760
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 491 Q----EVEMLKA--ENSRQAK-KIEFMKEEIQEVHLDYRQELSRLAEKTKG--KEDADHLRL-TLSQRDSELRSAKKTIQ 560
Cdd:NF041483 761 EadrrATELVSAaeQTAQQVRdSVAGLQEQAEEEIAGLRSAAEHAAERTRTeaQEEADRVRSdAYAERERASEDANRLRR 840
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 561 EVKADNQKVQLM--------LVEVRQHQEKILEENVRLRKGMADALAKIEE-YKRSWQNSQETCERLERESATKEDKLdk 631
Cdd:NF041483 841 EAQEETEAAKALaertvseaIAEAERLRSDASEYAQRVRTEASDTLASAEQdAARTRADAREDANRIRSDAAAQADRL-- 918
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17534555 632 LEEELQEKKQQIAESKELVTYLHSQIDAKQtkqpklGRRSTLLSTVSEMDTSVYMREAEEVRA 694
Cdd:NF041483 919 IGEATSEAERLTAEARAEAERLRDEARAEA------ERVRADAAAQAEQLIAEATGEAERLRA 975
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
401-628 |
3.64e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 3.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 401 EQIEELKTKMfsfEMIKKDHESAKNELSRTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQ 480
Cdd:COG4942 20 DAAAEAEAEL---EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 481 TSLESQRkvEQEVEMLKA--ENSRQAK-KIEFMKEEIQEV--HLDYRQELSRlAEKTKGKEDADHLRlTLSQRDSELRSA 555
Cdd:COG4942 97 AELEAQK--EELAELLRAlyRLGRQPPlALLLSPEDFLDAvrRLQYLKYLAP-ARREQAEELRADLA-ELAALRAELEAE 172
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17534555 556 KKTIQEVKADNQKVQLMLVEVRQHQEKILEenvRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDK 628
Cdd:COG4942 173 RAELEALLAELEEERAALEALKAERQKLLA---RLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
360-591 |
3.66e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.76 E-value: 3.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 360 LKQELEKERDDALADVQKIREvkrNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMgK 439
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPE---LNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKL-E 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 440 HLIMADQQCSTFKSLKESAEGSRRRAieqcNEMVVRIRDLQTSLESQRKVEQEVEMLKAEnsrqakkiefMKEEIQEVHL 519
Cdd:COG4717 123 KLLQLLPLYQELEALEAELAELPERL----EELEERLEELRELEEELEELEAELAELQEE----------LEELLEQLSL 188
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17534555 520 DYRQELSRLAektkgkEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLvEVRQHQEKILEENVRLR 591
Cdd:COG4717 189 ATEEELQDLA------EELEELQQRLAELEEELEEAQEELEELEEELEQLENEL-EAAALEERLKEARLLLL 253
|
|
| HCR |
pfam07111 |
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha ... |
110-642 |
3.89e-04 |
|
Alpha helical coiled-coil rod protein (HCR); This family consists of several mammalian alpha helical coiled-coil rod HCR proteins. The function of HCR is unknown but it has been implicated in psoriasis in humans and is thought to affect keratinocyte proliferation.
Pssm-ID: 284517 [Multi-domain] Cd Length: 749 Bit Score: 44.74 E-value: 3.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 110 KHHQSQIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHvlEKELSAKANDIFMVTKDLHdkneELTSF 189
Cdd:pfam07111 111 KAGQAEAEGLRAALAGAEMVRKNLEEGSQRELEEIQRLHQEQLSSLTQAH--EEALSSLTSKAEGLEKSLN----SLETK 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 190 RMEYVTKLSEANREKKALEEKLEKYKNDMKEndRKSLELNKEQVTTQNVLSEVrqlsaHFEFLTPVRKnasKIRELDEYH 269
Cdd:pfam07111 185 RAGEAKQLAEAQKEAELLRKQLSKTQEELEA--QVTLVESLRKYVGEQVPPEV-----HSQTWELERQ---ELLDTMQHL 254
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 270 QLSAKVIEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQTTTA---SLGDSEQATKY-----LHEENMKLTRQKA 341
Cdd:pfam07111 255 QEDRADLQATVELLQVRVQSLTHMLALQEEELTRKIQPSDSLEPEFPKkcrSLLNRWREKVFalmvqLKAQDLEHRDSVK 334
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 342 DIRCELLEARRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQI----EELKTKMFSFEMIK 417
Cdd:pfam07111 335 QLRGQVAELQEQVTSQSQEQAILQRALQDKAAEVEVERMSAKGLQMELSRAQEARRRQQQQTasaeEQLKFVVNAMSSTQ 414
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 418 KDHESAKNELSRTQEKLDQMGKHLIMADQQCSTFKSLKesaegSRRRAIEQCNEMVVRIRDLQTSLESQrkVEQEVEMLK 497
Cdd:pfam07111 415 IWLETTMTRVEQAVARIPSLSNRLSYAVRKVHTIKGLM-----ARKVALAQLRQESCPPPPPAPPVDAD--LSLELEQLR 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 498 AENSRQAKKIEFMKEEIQevhldyrQELSRL-----AEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLM 572
Cdd:pfam07111 488 EERNRLDAELQLSAHLIQ-------QEVGRAreqgeAERQQLSEVAQQLEQELQRAQESLASVGQQLEVARQGQQESTEE 560
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 573 LVEVRQH------------QEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDK---LDKLEEELQ 637
Cdd:pfam07111 561 AASLRQEltqqqeiygqalQEKVAEVETRLREQLSDTKRRLNEARREQAKAVVSLRQIQHRATQEKERnqeLRRLQDEAR 640
|
....*
gi 17534555 638 EKKQQ 642
Cdd:pfam07111 641 KEEGQ 645
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
418-645 |
4.57e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.91 E-value: 4.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 418 KDHESAKNELSRTQEKLDqmgkHLIMADQQCSTFKSLKEsaegsRRRAIEQCNEMV---VRIRDLQTSLESQRKVEQEVE 494
Cdd:COG4913 235 DDLERAHEALEDAREQIE----LLEPIRELAERYAAARE-----RLAELEYLRAALrlwFAQRRLELLEAELEELRAELA 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 495 MLKAENSRQAKKIEFMKEEIQEVHLDYRQElsrlaektkGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLV 574
Cdd:COG4913 306 RLEAELERLEARLDALREELDELEAQIRGN---------GGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLP 376
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17534555 575 EVrqhqEKILEENVRLRKGMADALAKIEEykrswqnsqetceRLERESATKEDKLDKLEEELQEKKQQIAE 645
Cdd:COG4913 377 AS----AEEFAALRAEAAALLEALEEELE-------------ALEEALAEAEAALRDLRRELRELEAEIAS 430
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
475-653 |
5.78e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 43.74 E-value: 5.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 475 RIRDLQTSLESQRKVEQEVEMLKAENSRQA-KKIEFMKEEIQEVhldyRQELSRLaektkgKEDADHLRLTLSQRDSELR 553
Cdd:COG4372 7 KVGKARLSLFGLRPKTGILIAALSEQLRKAlFELDKLQEELEQL----REELEQA------REELEQLEEELEQARSELE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 554 SAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLE 633
Cdd:COG4372 77 QLEEELEELNEQLQAAQAELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELE 156
|
170 180
....*....|....*....|
gi 17534555 634 EELQEKKQQIAESKELVTYL 653
Cdd:COG4372 157 EQLESLQEELAALEQELQAL 176
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
54-265 |
5.86e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 43.60 E-value: 5.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 54 AENIIQDLRSERDALHETlvdkaglnesvIIEQSKRVSTQETRIyrrdvNLLEDDLKHHQSQIRILQNKCSTLEMEKQTL 133
Cdd:COG4942 18 QADAAAEAEAELEQLQQE-----------IAELEKELAALKKEE-----KALLKQLAALERRIAALARRIRALEQELAAL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 134 QETIQRAQDDKKETETELESSRSRLHVLEKEL--------------SAKANDIFMVTKDLHDKNEELTSFRMEYVTKLSE 199
Cdd:COG4942 82 EAELAELEKEIAELRAELEAQKEELAELLRALyrlgrqpplalllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAE 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17534555 200 ANREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEV-RQLSAHFEFLTPVRKNASKIREL 265
Cdd:COG4942 162 LAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLeKELAELAAELAELQQEAEELEAL 228
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
125-371 |
5.99e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 44.52 E-value: 5.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 125 TLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEK--ELSAKANDIFMVTKDLHDKNEELTSfrmeyvtkLSEANR 202
Cdd:COG4913 614 ALEAELAELEEELAEAEERLEALEAELDALQERREALQRlaEYSWDEIDVASAEREIAELEAELER--------LDASSD 685
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 203 EKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVR-QLSAHFEFLTPVRKNASKIRELDEYHQLSAKVIEESMN 281
Cdd:COG4913 686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEeELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER 765
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 282 DLKiknETLTKELSDKTELVKMKNEELEDLRQT-------TTASLGDS-EQATKYLHE----ENMKLTRQKADIRcELLE 349
Cdd:COG4913 766 ELR---ENLEERIDALRARLNRAEEELERAMRAfnrewpaETADLDADlESLPEYLALldrlEEDGLPEYEERFK-ELLN 841
|
250 260
....*....|....*....|..
gi 17534555 350 aRRKVEGFDKLKQELEKERDDA 371
Cdd:COG4913 842 -ENSIEFVADLLSKLRRAIREI 862
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
44-394 |
7.00e-04 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 43.73 E-value: 7.00e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 44 HEDLKKRVLDAENIIQDLRSERDALHETLVDKAGLNESVIIEQSKRVSTQETRIYRrdVNLLEDDlkhhqsqIRILQNKC 123
Cdd:pfam07888 75 RRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEAR--IRELEED-------IKTLTQRV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 124 STLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDiFMVTKDLHDKNEELTSFRMEYVTKLSEANRE 203
Cdd:pfam07888 146 LERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKE-FQELRNSLAQRDTQVLQLQDTITTLTQKLTT 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 204 KKALEEKLEKYKNDMKENDRKsleLNKEQVTTQNVLSEVRQLSAHFEfltpvRKNASKIRELDEYHQLSAKVIEESMNdL 283
Cdd:pfam07888 225 AHRKEAENEALLEELRSLQER---LNASERKVEGLGEELSSMAAQRD-----RTQAELHQARLQAAQLTLQLADASLA-L 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 284 KIKNETLTKELSDKTELVKMKNEELEDLRQtttaslgDSEQATKYLHEENMK-------LTRQKADIRCELLEARRKVEG 356
Cdd:pfam07888 296 REGRARWAQERETLQQSAEADKDRIEKLSA-------ELQRLEERLQEERMErekleveLGREKDCNRVQLSESRRELQE 368
|
330 340 350
....*....|....*....|....*....|....*...
gi 17534555 357 FDKLKQELEKERDDALADVQKIREVKRNVERELQSLTS 394
Cdd:pfam07888 369 LKASLRVAQKEKEQLQAEKQELLEYIRQLEQRLETVAD 406
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
378-664 |
9.16e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 9.16e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 378 IREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMGKHLIMADQQCSTFKSLKES 457
Cdd:COG4372 26 IAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELES 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 458 AEGSRRRAIEQCNEMVVRIRDLQtslESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVhldyRQELSRLaEKTKGKED 537
Cdd:COG4372 106 LQEEAEELQEELEELQKERQDLE---QQRKQLEAQIAELQSEIAEREEELKELEEQLESL----QEELAAL-EQELQALS 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 538 ADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCER 617
Cdd:COG4372 178 EAEAEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVIL 257
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 17534555 618 LERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQ 664
Cdd:COG4372 258 KEIEELELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNL 304
|
|
| HMMR_N |
pfam15905 |
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ... |
120-313 |
1.15e-03 |
|
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.
Pssm-ID: 464932 [Multi-domain] Cd Length: 329 Bit Score: 42.49 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 120 QNKCSTLEMEkqtLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDIfmvtKDLHDKNEELTSFRME---YVTK 196
Cdd:pfam15905 151 QKKMSSLSME---LMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKV----AQLEEKLVSTEKEKIEeksETEK 223
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 197 LSEANREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEVRQLSAhfefltpvrknaSKIRELDEYHQLSAKVI 276
Cdd:pfam15905 224 LLEYITELSCVSEQVEKYKLDIAQLEELLKEKNDEIESLKQSLEEKEQELS------------KQIKDLNEKCKLLESEK 291
|
170 180 190
....*....|....*....|....*....|....*..
gi 17534555 277 EESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQ 313
Cdd:pfam15905 292 EELLREYEEKEQTLNAELEELKEKLTLEEQEHQKLQQ 328
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
35-682 |
1.35e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 43.50 E-value: 1.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 35 QVIDLNNESHEDLKK--------RVLDAENIIQDLRSERDALHETLVDKAGLNESVIIEQSKRVSTQET----------- 95
Cdd:TIGR01612 627 KIIENNNAYIDELAKispyqvpeHLKNKDKIYSTIKSELSKIYEDDIDALYNELSSIVKENAIDNTEDKaklddlkskid 706
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 96 RIYRRDVNLLEDDLKHHQSQIRILQNKCST--LEMEKQTLQETiqraqddKKETETELESSRSRlhvlEKELSAKANDIF 173
Cdd:TIGR01612 707 KEYDKIQNMETATVELHLSNIENKKNELLDiiVEIKKHIHGEI-------NKDLNKILEDFKNK----EKELSNKINDYA 775
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 174 MVTKDLHDKNEELTSFRMEYVTKLSEANREKKALEEKLEKYKNDMKENDRKSLELNKeqvttqnVLSEVRQLSAhfEFLT 253
Cdd:TIGR01612 776 KEKDELNKYKSKISEIKNHYNDQINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFK-------IINEMKFMKD--DFLN 846
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 254 PVrknaSKIRELDEYHQLSAKVIEESMNDL--KIKNETLTKELS-------DKTELVKMKNEELEDLRQtttaSLGDSEQ 324
Cdd:TIGR01612 847 KV----DKFINFENNCKEKIDSEHEQFAELtnKIKAEISDDKLNdyekkfnDSKSLINEINKSIEEEYQ----NINTLKK 918
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 325 ATKYLH-----EENMKLTRQKADIRCELLEARRKV-EGFDKLKQELEKERDDALADvqKIREVKRnVERELqSLTSLMAE 398
Cdd:TIGR01612 919 VDEYIKicentKESIEKFHNKQNILKEILNKNIDTiKESNLIEKSYKDKFDNTLID--KINELDK-AFKDA-SLNDYEAK 994
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 399 RDEQIEEL--------KTKMFSFEMIKKDHESAKNELSRTQEKLDQMGKHLIMADQqcSTFKSLKESAEGSRRRAIEQCN 470
Cdd:TIGR01612 995 NNELIKYFndlkanlgKNKENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIH--TSIYNIIDEIEKEIGKNIELLN 1072
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 471 EMVvrIRDLQTSLESQRKVEQEV------EMLKAENSRQAKKIEFMKEEIQEVHLDYRQELSRLAE-KTKGKEDADHLRL 543
Cdd:TIGR01612 1073 KEI--LEEAEINITNFNEIKEKLkhynfdDFGKEENIKYADEINKIKDDIKNLDQKIDHHIKALEEiKKKSENYIDEIKA 1150
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 544 TLSQRDselRSAKKTI--QEVKADNQKVQLMLVEVrqHQEKILEENVrlrKGMADALAKIEEykrswqnSQETCERLERE 621
Cdd:TIGR01612 1151 QINDLE---DVADKAIsnDDPEEIEKKIENIVTKI--DKKKNIYDEI---KKLLNEIAEIEK-------DKTSLEEVKGI 1215
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17534555 622 SATKEDKLDK--LEEELQEKKQQIAESKELVTYLHSQIDAKQTKQPKLGRRSTLLSTVSEMDT 682
Cdd:TIGR01612 1216 NLSYGKNLGKlfLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEMGIEMDIKAEMET 1278
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
140-354 |
1.65e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 42.51 E-value: 1.65e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 140 AQDDKKETETELESSRSRLHVLEKELSAKANDIFMVTKDLHDKNEELTSFRmeyvTKLSEANREKKALEEKLEKYKNDMK 219
Cdd:COG3883 14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQ----AEIDKLQAEIAEAEAEIEERREELG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 220 ENDRkSLELNKEQVTTQNVLSEVRQLSahfEFLTpvrkNASKIRELDEYHQlsaKVIEEsMNDLKIKNETLTKELSDKTE 299
Cdd:COG3883 90 ERAR-ALYRSGGSVSYLDVLLGSESFS---DFLD----RLSALSKIADADA---DLLEE-LKADKAELEAKKAELEAKLA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 17534555 300 LVKMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKV 354
Cdd:COG3883 158 ELEALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAA 212
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
256-606 |
1.75e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 42.52 E-value: 1.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 256 RKNASKIRELDEYHQ--LSAKVIEESMndlKIKNETLTKELSDKTELVKMKNEELedlrqtTTASLGDSEQ----ATKYL 329
Cdd:PRK04778 25 KRNYKRIDELEERKQelENLPVNDELE---KVKKLNLTGQSEEKFEEWRQKWDEI------VTNSLPDIEEqlfeAEELN 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 330 HEENMKLTRQKADIRCELLEA-----RRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIE 404
Cdd:PRK04778 96 DKFRFRKAKHEINEIESLLDLieediEQILEELQELLESEEKNREEVEQLKDLYRELRKSLLANRFSFGPALDELEKQLE 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 405 ELKTKMFSFEMIKK--DHESAKNELSRTQEKLDQMGKHL-----IMADQQcSTFKS-LKESAEGSRRrAIEQC-----NE 471
Cdd:PRK04778 176 NLEEEFSQFVELTEsgDYVEAREILDQLEEELAALEQIMeeipeLLKELQ-TELPDqLQELKAGYRE-LVEEGyhldhLD 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 472 MVVRIRDLQTSLESQRK--VEQEVEMLKAENSRQAKKIEFM----------KEEIQEVHLDYRQELSRLAEKTKG-KEDA 538
Cdd:PRK04778 254 IEKEIQDLKEQIDENLAllEELDLDEAEEKNEEIQERIDQLydilerevkaRKYVEKNSDTLPDFLEHAKEQNKElKEEI 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 539 DHLRL--TLSQRDSEL-RSAKKTIQEVKADNQK--------------VQLMLVEVRQH-------QEKILEENVRLRKGM 594
Cdd:PRK04778 334 DRVKQsyTLNESELESvRQLEKQLESLEKQYDEiteriaeqeiayseLQEELEEILKQleeiekeQEKLSEMLQGLRKDE 413
|
410
....*....|..
gi 17534555 595 ADALAKIEEYKR 606
Cdd:PRK04778 414 LEAREKLERYRN 425
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
120-578 |
2.32e-03 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 42.25 E-value: 2.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 120 QNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLE----KELSAKANDIFMVTKDLHDKNEELTSFRMEYVT 195
Cdd:COG5185 157 ETGIIKDIFGKLTQELNQNLKKLEIFGLTLGLLKGISELKKAEpsgtVNSIKESETGNLGSESTLLEKAKEIINIEEALK 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 196 KLSEANREKKALEEKLEKYKNDMKENDRKSLELNKEQVTTQNVLSEvrqlsahfefltpvrkNASKIRELDEYHQlsaKV 275
Cdd:COG5185 237 GFQDPESELEDLAQTSDKLEKLVEQNTDLRLEKLGENAESSKRLNE----------------NANNLIKQFENTK---EK 297
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 276 IEESMNDLKIKNETLTKELSDKTELVKMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVE 355
Cdd:COG5185 298 IAEYTKSIDIKKATESLEEQLAAAEAEQELEESKRETETGIQNLTAEIEQGQESLTENLEAIKEEIENIVGEVELSKSSE 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 356 GFDKLKQELEKERDDALADVQKIREVKRNVereLQSLTSLMAERDEQIEELKTkmfsfemikkDHESAKNELSRTQEKLD 435
Cdd:COG5185 378 ELDSFKDTIESTKESLDEIPQNQRGYAQEI---LATLEDTLKAADRQIEELQR----------QIEQATSSNEEVSKLLN 444
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 436 QmgkhlimadqqcstfksLKESAEGSRRRAIEQCNEMVVrirdlqtslESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQ 515
Cdd:COG5185 445 E-----------------LISELNKVMREADEESQSRLE---------EAYDEINRSVRSKKEDLNEELTQIESRVSTLK 498
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17534555 516 EVHLDYRQELSRLAEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQ 578
Cdd:COG5185 499 ATLEKLRAKLERQLEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNAKTDGQ 561
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
349-607 |
2.48e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 41.81 E-value: 2.48e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 349 EARRKVEGFDKLKQELEKERddalADVQKIREVKRNVERELQSLTSLMAERDEQIEE----LKTKMFSFEMIKKDHESAK 424
Cdd:COG4372 32 QLRKALFELDKLQEELEQLR----EELEQAREELEQLEEELEQARSELEQLEEELEElneqLQAAQAELAQAQEELESLQ 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 425 NELSRTQEKLDQMGKHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLE---------SQRKVEQEVEM 495
Cdd:COG4372 108 EEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAaleqelqalSEAEAEQALDE 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 496 LKAENSRQAKKIEFMKEEIQEVHLDYR---QELSRLAEKTKGKEDADHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLM 572
Cdd:COG4372 188 LLKEANRNAEKEEELAEAEKLIESLPRelaEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEELELAI 267
|
250 260 270
....*....|....*....|....*....|....*
gi 17534555 573 LVEVRQHQEKILEENVRLRKGMADALAKIEEYKRS 607
Cdd:COG4372 268 LVEKDTEEEELEIAALELEALEEAALELKLLALLL 302
|
|
| PHA01351 |
PHA01351 |
putative minor structural protein |
109-429 |
2.60e-03 |
|
putative minor structural protein
Pssm-ID: 107029 Cd Length: 1070 Bit Score: 42.24 E-value: 2.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 109 LKHHQSQIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSR--SRLHVLEKELSAKANDIFMVTKDLhdkNEEL 186
Cdd:PHA01351 478 IQTNQLLLRQLQQIVSLGIFDQKKIKEELKANKFNEQVALQILESELqfAQLQNQLKEYQFKLNNFLISPQDL---EKDL 554
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 187 TS--FRMEYVTKLSEANREKKALEEKLEKYKN-------DMKENDR--KSLELNKEQVTT-QNVLSEVRQLSAhfeFLTP 254
Cdd:PHA01351 555 KHlgFDSAIISALIYENQVEQLIKFQLNNIESlakkgylSLDEIKKqfKAIGIIKEYEDAfINFYNQELQISA---FLTI 631
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 255 VRknaSKIRELdeyhQLSAKVIEESMNDLKIkNETLTKELSDK---TELVKMKNEELEDLRQTTTASLGDSEQATKYLHE 331
Cdd:PHA01351 632 LK---SQLRQF----QIDPKEAETELKKLNI-NEYLANQIIQEeynINIAKLQLSVLETIAKTLYYDQQQLSGELKKIHK 703
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 332 ENMKLTrqkadircELLEARRKVEGFDKLKQ-ELEKERDDALADVQKIREVKRNVERELQSLTSlmaERDEQIEELKTKM 410
Cdd:PHA01351 704 DKTALE--------LYITKFYYEYIYPKISNyHLQLARHGILSDISKLPKEVNDYEYKPAVLTY---QTTLEIEYIKESL 772
|
330
....*....|....*....
gi 17534555 411 FSFEMikkDHESAKNELSR 429
Cdd:PHA01351 773 KDLEI---KPKTAINELEK 788
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
555-691 |
2.67e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 42.07 E-value: 2.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 555 AKKTIQEVK--ADNQKvQLMLVEVRQHQEKI---LEENVRLRKgmadalakiEEYKRSWQNSQETCERLEResatKEDKL 629
Cdd:PRK12704 40 AKRILEEAKkeAEAIK-KEALLEAKEEIHKLrneFEKELRERR---------NELQKLEKRLLQKEENLDR----KLELL 105
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17534555 630 DKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQ-PKLGR---------RSTLLSTV---SEMDTSVYMREAEE 691
Cdd:PRK12704 106 EKREEELEKKEKELEQKQQELEKKEEELEELIEEQlQELERisgltaeeaKEILLEKVeeeARHEAAVLIKEIEE 180
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
109-649 |
4.39e-03 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 41.58 E-value: 4.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 109 LKHHQSQIRILQNKCSTLE--MEKQT-LQETIQRAQDDKKETETELESSRSRLhvlEKELSAKANDIFMVTKDL-----H 180
Cdd:TIGR01612 916 LKKVDEYIKICENTKESIEkfHNKQNiLKEILNKNIDTIKESNLIEKSYKDKF---DNTLIDKINELDKAFKDAslndyE 992
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 181 DKNEELtsfrMEYVTKLSE------ANREKKALEEKlEKYKNDMKEndrKSLELNKE--------QVTTQNVLSEVRQL- 245
Cdd:TIGR01612 993 AKNNEL----IKYFNDLKAnlgknkENMLYHQFDEK-EKATNDIEQ---KIEDANKNipnieiaiHTSIYNIIDEIEKEi 1064
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 246 -----SAHFEFLTPVR---KNASKIRELDEYHQLSAKVIEESM----------NDLKIKNETLTKELSDKTElVKMKNEE 307
Cdd:TIGR01612 1065 gknieLLNKEILEEAEiniTNFNEIKEKLKHYNFDDFGKEENIkyadeinkikDDIKNLDQKIDHHIKALEE-IKKKSEN 1143
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 308 LEDLRQTTTASLGDSEQATKYlHEENMKLTRQKADIRCELLEARRKVEGFDKLKQELEK-ERDD-ALADV---------- 375
Cdd:TIGR01612 1144 YIDEIKAQINDLEDVADKAIS-NDDPEEIEKKIENIVTKIDKKKNIYDEIKKLLNEIAEiEKDKtSLEEVkginlsygkn 1222
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 376 ------QKIREVKRNVERELQSLTSLMaerdEQIEELKTKMFSFEMIKKDHESAKNELSRTQEKLDQMGKHLIMA---DQ 446
Cdd:TIGR01612 1223 lgklflEKIDEEKKKSEHMIKAMEAYI----EDLDEIKEKSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISkkhDE 1298
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 447 QCSTF--KSLKESAEGSRRRAIEQCNemvvriRDLQTSLESQRKVEQEVEMLKAE--NSRQAKKIEFMKEEIQEVHlDYR 522
Cdd:TIGR01612 1299 NISDIreKSLKIIEDFSEESDINDIK------KELQKNLLDAQKHNSDINLYLNEiaNIYNILKLNKIKKIIDEVK-EYT 1371
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 523 QELSRLAEKTKGKEDADHLRLTLSQRDSELRSAKKTIqEVKADNQKVQLMLVEVRQHQEKILEENVRLRKGMADAlakiE 602
Cdd:TIGR01612 1372 KEIEENNKNIKDELDKSEKLIKKIKDDINLEECKSKI-ESTLDDKDIDECIKKIKELKNHILSEESNIDTYFKNA----D 1446
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17534555 603 EYKRS----------WQNSQETCERLERESATKE------------DKLDKLEEELQEKKQQIAESKEL 649
Cdd:TIGR01612 1447 ENNENvlllfkniemADNKSQHILKIKKDNATNDhdfninelkehiDKSKGCKDEADKNAKAIEKNKEL 1515
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
439-753 |
4.79e-03 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 41.57 E-value: 4.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 439 KHLIMADQQCSTFKSLKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEI---- 514
Cdd:TIGR00606 151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKALETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQItske 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 515 ------QEVHLDYRQELSRLAEKTKGKEdadHLRLTLSQRDSELRSAKKTIQEVKADNQKVQLMLVEVRQHQEkileenv 588
Cdd:TIGR00606 231 aqlessREIVKSYENELDPLKNRLKEIE---HNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTD------- 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 589 rlrkgmadalakiEEYKRSWQNSQETCERLERESATKEDKLDKLEEELQEKKQQIAESKELVTYLHSQIDAKQTKQPKLG 668
Cdd:TIGR00606 301 -------------EQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARD 367
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 669 RRSTLLSTVSEMD----------------TSVYMREAEEVRALEEQRQALMSNLAEKRRQLV---DSKKSQSTANTTIVT 729
Cdd:TIGR00606 368 SLIQSLATRLELDgfergpfserqiknfhTLVIERQEDEAKTAAQLCADLQSKERLKQEQADeirDEKKGLGRTIELKKE 447
|
330 340
....*....|....*....|....
gi 17534555 730 TTTTEISKSSQSASELSNRQGTMR 753
Cdd:TIGR00606 448 ILEKKQEELKFVIKELQQLEGSSD 471
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
471-713 |
4.92e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 4.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 471 EMVVRIRDLQTSLESQRKVEQEVEmlKAEnsRQAKKIEfmkeEIQEVHLDYRQELSRLAEKtkgKEDADHLRLTLSQRDS 550
Cdd:COG4913 222 DTFEAADALVEHFDDLERAHEALE--DAR--EQIELLE----PIRELAERYAAARERLAEL---EYLRAALRLWFAQRRL 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 551 ELRSAKktiqevkadnqkvqlmLVEVRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQ-ETCERLEREsatkedkL 629
Cdd:COG4913 291 ELLEAE----------------LEELRAELARLEAELERLEARLDALREELDELEAQIRGNGgDRLEQLERE-------I 347
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 630 DKLEEELQEKKQQIAESKELVTYLHSQIDAKqtkqpklgrRSTLLSTVSEMDTSVyMREAEEVRALEEQRQALMSNLAEK 709
Cdd:COG4913 348 ERLERELEERERRRARLEALLAALGLPLPAS---------AEEFAALRAEAAALL-EALEEELEALEEALAEAEAALRDL 417
|
....
gi 17534555 710 RRQL 713
Cdd:COG4913 418 RREL 421
|
|
| Leu_zip |
pfam15294 |
Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 ... |
286-456 |
6.30e-03 |
|
Leucine zipper; This family includes Leucine zipper transcription factor-like protein 1 (LZTFL1) and Leucine zipper protein 2 (LUZP2).
Pssm-ID: 464620 [Multi-domain] Cd Length: 276 Bit Score: 40.07 E-value: 6.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 286 KNETLTKELSDKTELVKMKneeLEDLRQTTTASLGDSEQATkyLHEENMKLTRQKADIRCELLEARRKvegfdklKQELE 365
Cdd:pfam15294 100 EREFTSSNKKPNFELNKPK---LEPLNEGGGSALLHMEIER--LKEENEKLKERLKTLESQATQALDE-------KSKLE 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 366 KerddALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFSFEMIKKDHE----SAKNELSRTQEKLDQMGKHL 441
Cdd:pfam15294 168 K----ALKDLQKEQGAKKDVKSNLKEISDLEEKMAALKSDLEKTLNASTALQKSLEedlaSTKHELLKVQEQLEMAEKEL 243
|
170
....*....|....*
gi 17534555 442 IMADQQCSTFKSLKE 456
Cdd:pfam15294 244 EKKFQQTAAYRNMKE 258
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
569-748 |
6.86e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 40.52 E-value: 6.86e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 569 VQLMLVE-VRQHQEKILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLEREsatkedkLDKLEEELQEKKQQIAESK 647
Cdd:COG4717 43 IRAMLLErLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEE-------LEELEEELEELEAELEELR 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 648 ELVTYLHSQIDAkqtkQPKLGRRSTLLSTVSEMDTSV--YMREAEEVRALEEQRQALMSNLAEKRRQLVDSKKSQSTANT 725
Cdd:COG4717 116 EELEKLEKLLQL----LPLYQELEALEAELAELPERLeeLEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE 191
|
170 180
....*....|....*....|...
gi 17534555 726 TIVTTTTTEISKSSQSASELSNR 748
Cdd:COG4717 192 EELQDLAEELEELQQRLAELEEE 214
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
478-667 |
7.06e-03 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 40.20 E-value: 7.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 478 DLQTSLESQRKVEQEVEMLKAENSRQAKKIEFMKEEIQEVhldyRQELSRL-AEKTKGKEDADHLRLTLSQRDSELRSAK 556
Cdd:COG3883 17 QIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNEL----QAELEALqAEIDKLQAEIAEAEAEIEERREELGERA 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 557 KTIQEVKADNQKVQlMLVEVRQHQEkILEENVRLRKGMADALAKIEEYKRSWQNSQETCERLERESATKEDKLDKLEEEL 636
Cdd:COG3883 93 RALYRSGGSVSYLD-VLLGSESFSD-FLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAK 170
|
170 180 190
....*....|....*....|....*....|.
gi 17534555 637 QEKKQQIAESKELVTYLHSQIDAKQTKQPKL 667
Cdd:COG3883 171 AELEAQQAEQEALLAQLSAEEAAAEAQLAEL 201
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
45-172 |
7.06e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 7.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 45 EDLKKRVLDAENIIQDLRSERDALHETLVDKaglnESVIIEQSKRVSTQETRIYRRDVNLLE----DDLKHHQSQIRILQ 120
Cdd:COG1579 27 KELPAELAELEDELAALEARLEAAKTELEDL----EKEIKRLELEIEEVEARIKKYEEQLGNvrnnKEYEALQKEIESLK 102
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 17534555 121 NKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELSAKANDI 172
Cdd:COG1579 103 RRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAEL 154
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
346-508 |
8.92e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 39.52 E-value: 8.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 346 ELLEARRKVEGFDKLKQELEKERDDALADVQKIREVKRNVERELQSLTSLMAERDEQIEELKTKMFS------FEMIKKD 419
Cdd:COG1579 18 ELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnkeYEALQKE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 420 HESAKNELSRTQEK-LDQMGKhlimadqqcstfkslKESAEGSRRRAIEQCNEMVVRIRDLQTSLESQR-KVEQEVEMLK 497
Cdd:COG1579 98 IESLKRRISDLEDEiLELMER---------------IEELEEELAELEAELAELEAELEEKKAELDEELaELEAELEELE 162
|
170
....*....|.
gi 17534555 498 AENSRQAKKIE 508
Cdd:COG1579 163 AEREELAAKIP 173
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
35-337 |
9.07e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 40.39 E-value: 9.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 35 QVIDLNNESHEDLKKRVLDAENIIQDLRSERDALHETLvdKAGLNESVIIEQSKRVSTQEtriyrrdVNLLEDDLKHHQS 114
Cdd:TIGR04523 433 ETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQL--KVLSRSINKIKQNLEQKQKE-------LKSKEKELKKLNE 503
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 115 QIRILQNKCSTLEMEKQTLQETIQRAQDDKKETETELESSRSRLHVLEKELsakanDIFMVTKDLHDKNEELTSFRMEYv 194
Cdd:TIGR04523 504 EKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFEL-----KKENLEKEIDEKNKEIEELKQTQ- 577
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 195 TKLSEANREKKALEEKLEKYKNDMK----ENDRKSLELNKEQVTTQnvlSEVRQLSahfEFLTPVRKNASKIRELDEYHQ 270
Cdd:TIGR04523 578 KSLKKKQEEKQELIDQKEKEKKDLIkeieEKEKKISSLEKELEKAK---KENEKLS---SIIKNIKSKKNKLKQEVKQIK 651
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17534555 271 LSAKVIEESMNDLKIKNETLTKELSDKTELVKMKNEEL------EDLRQTTTASLGDSEQATKYLHEENMKLT 337
Cdd:TIGR04523 652 ETIKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELslhykkYITRMIRIKDLPKLEEKYKEIEKELKKLD 724
|
|
| WEMBL |
pfam05701 |
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required ... |
87-629 |
9.32e-03 |
|
Weak chloroplast movement under blue light; WEMBL consists of several plant proteins required for the chloroplast avoidance response under high intensity blue light. This avoidance response consists in the relocation of chloroplasts on the anticlinal side of exposed cells. Acts in association with PMI2 to maintain the velocity of chloroplast photo-relocation movement via the regulation of cp-actin filaments. Thus several member-sequences are described as "myosin heavy chain-like".
Pssm-ID: 461718 [Multi-domain] Cd Length: 562 Bit Score: 40.01 E-value: 9.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 87 SKRVSTQETRiyrrdvNLLEDDLKHHQSQIRILQNKCSTLEMEK-QTLQE-------------TIQRAQDDKKETETELE 152
Cdd:pfam05701 28 AHRIQTVERR------KLVELELEKVQEEIPEYKKQSEAAEAAKaQVLEElestkrlieelklNLERAQTEEAQAKQDSE 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 153 SSRSRLHVLEK----ELSAKANDIFMVTKDLHDK--------NEELTSFRMEYVTKLSEANREKKALEEKLEKykndMKE 220
Cdd:pfam05701 102 LAKLRVEEMEQgiadEASVAAKAQLEVAKARHAAavaelksvKEELESLRKEYASLVSERDIAIKRAEEAVSA----SKE 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 221 NDRKSLELNKEQVTTQNVLSEVRqlSAHFEfLTPVRKNASKIRELD-------------EYHQLSAKVIeeSMNDLKIKN 287
Cdd:pfam05701 178 IEKTVEELTIELIATKESLESAH--AAHLE-AEEHRIGAALAREQDklnwekelkqaeeELQRLNQQLL--SAKDLKSKL 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 288 ETLTKELSD-KTELV-----KMKNEELED--LRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEArrkvegfDK 359
Cdd:pfam05701 253 ETASALLLDlKAELAaymesKLKEEADGEgnEKKTSTSIQAALASAKKELEEVKANIEKAKDEVNCLRVAA-------AS 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 360 LKQELEKERDDaLADVQKiREVKRNVerelqSLTSLMAERDEQIEELktkmfsfEMIKKDHESAKNELSRTQEKLDQmgk 439
Cdd:pfam05701 326 LRSELEKEKAE-LASLRQ-REGMASI-----AVSSLEAELNRTKSEI-------ALVQAKEKEAREKMVELPKQLQQ--- 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 440 hlimADQQCSTFKSLKESAEgsrrraieqcnemvvrirdlqtslESQRKVEQEVEMLKAENSRQAKKIEFMKEEIqevhl 519
Cdd:pfam05701 389 ----AAQEAEEAKSLAQAAR------------------------EELRKAKEEAEQAKAAASTVESRLEAVLKEI----- 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 520 dyrqELSRLAEKT-----KGKEDADHLRLTLSQRDSElrsakktiqevkadnQKVQLMLVEVRQHQEKILEENVRLRKGM 594
Cdd:pfam05701 436 ----EAAKASEKLalaaiKALQESESSAESTNQEDSP---------------RGVTLSLEEYYELSKRAHEAEELANKRV 496
|
570 580 590
....*....|....*....|....*....|....*
gi 17534555 595 ADALAKIEEYKRSWQNSQETCERLERESATKEDKL 629
Cdd:pfam05701 497 AEAVSQIEEAKESELRSLEKLEEVNREMEERKEAL 531
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
302-441 |
9.34e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 40.23 E-value: 9.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17534555 302 KMKNEELEDLRQTTTASLGDSEQATKYLHEENMKLTRQKADIRCELLEARRKVEGFD----KLKQELEKERDDALADVQK 377
Cdd:COG2433 384 ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDerieRLERELSEARSEERREIRK 463
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17534555 378 IREVKRnVERELQSLTSLMAERDEQIEELKtkmfsfemikkdhesaknelsrtqEKLDQMGKHL 441
Cdd:COG2433 464 DREISR-LDREIERLERELEEERERIEELK------------------------RKLERLKELW 502
|
|
| |
