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Conserved domains on  [gi|17554374|ref|NP_498935|]
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Single-stranded DNA-binding protein, mitochondrial [Caenorhabditis elegans]

Protein Classification

single-stranded DNA-binding protein( domain architecture ID 10450532)

single-stranded DNA (ssDNA)-binding protein plays a key role in DNA replication, recombination, and repair

CATH:  2.40.50.140
Gene Ontology:  GO:0003697|GO:0006260
PubMed:  27838363
SCOP:  4000346

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 54-159 7.23e-31

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


:

Pssm-ID: 425680  Cd Length: 103  Bit Score: 107.71  E-value: 7.23e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374    54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQdGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLHY 133
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDR-GEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQT 79

                          90       100
                  ....*....|....*....|....*.
gi 17554374   134 sGGQKDEQGNRTQRnTYIIAQTVQPL 159
Cdd:pfam00436  80 -RKYEDQEGQKRYV-TEIVADEVQFL 103
 
Name Accession Description Interval E-value
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 54-159 7.23e-31

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 107.71  E-value: 7.23e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374    54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQdGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLHY 133
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDR-GEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQT 79

                          90       100
                  ....*....|....*....|....*.
gi 17554374   134 sGGQKDEQGNRTQRnTYIIAQTVQPL 159
Cdd:pfam00436  80 -RKYEDQEGQKRYV-TEIVADEVQFL 103
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 57-159 5.17e-24

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 89.98  E-value: 5.17e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374  57 VELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGTTlDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLHYSGG 136
Cdd:cd04496   1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRDEEE-EETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSW 79

                        90       100
                ....*....|....*....|...
gi 17554374 137 QKDEQGNRTQrnTYIIAQTVQPL 159
Cdd:cd04496  80 EDKDGQKRYG--TEVVADRIEFL 100
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
54-169 5.34e-24

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 90.28  E-value: 5.34e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374  54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLHY 133
Cdd:COG0629   1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQDGEWKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRT 80

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 17554374 134 SGGQkDEQGNRTQRnTYIIAQTVQPLARAARENPDQ 169
Cdd:COG0629  81 RSWE-DKDGQKRYT-TEVVADEIQFLGSRPSGGGGG 114
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 53-159 2.66e-19

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 79.77  E-value: 2.66e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374    53 SVNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLH 132
Cdd:TIGR00621   3 MVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQDGEWKEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLR 82

                          90       100
                  ....*....|....*....|....*..
gi 17554374   133 YSGGQkDEQGNRTQRnTYIIAQTVQPL 159
Cdd:TIGR00621  83 TRKWE-DQNGQKRSK-TEIIADNVQLL 107
PRK05733 PRK05733
single-stranded DNA-binding protein; Provisional
 51-170 4.68e-12

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235585 [Multi-domain]  Cd Length: 172  Bit Score: 60.71  E-value: 4.68e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   51 AYSVNKVELVGGVALDPLYKTGRNGkpylifNIITN-------SYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGS 123
Cdd:PRK05733   2 ARGVNKVILVGTCGQDPEVRYLPNG------NAVTNlslatseQWTDKQSGQKVERTEWHRVSLFGKVAEIAGEYLRKGS 75

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 17554374  124 RLMVQGRLHYSGGQKDEQGNRTQRNTYIIAQTVQPLARAArENPDQH 170
Cdd:PRK05733  76 QVYIEGKLQTREWEKDGIKRYTTEIVVDMQGTMQLLGGRP-QGDDQG 121
 
Name Accession Description Interval E-value
SSB pfam00436
Single-strand binding protein family; This family includes single stranded binding proteins ...
 54-159 7.23e-31

Single-strand binding protein family; This family includes single stranded binding proteins and also the primosomal replication protein N (PriB). PriB forms a complex with PriA, PriC and ssDNA.


Pssm-ID: 425680  Cd Length: 103  Bit Score: 107.71  E-value: 7.23e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374    54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQdGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLHY 133
Cdd:pfam00436   1 MNKVILVGRLTRDPELRYTPNGNAVANFTLATNRRFKDR-GEGDEETDFHRVVVFGKLAEVAAQYLKKGSLVYVEGRLQT 79

                          90       100
                  ....*....|....*....|....*.
gi 17554374   134 sGGQKDEQGNRTQRnTYIIAQTVQPL 159
Cdd:pfam00436  80 -RKYEDQEGQKRYV-TEIVADEVQFL 103
SSB_OBF cd04496
SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs ...
 57-159 5.17e-24

SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date oligomerize to bring together four OB folds in their active state. The majority (e.g. Escherichia coli SSB) have a single OB fold per monomer, which oligomerize to form a homotetramer. However, Deinococcus and Thermus SSB proteins have two OB folds per monomer, which oligomerize to form a homodimer. Mycobacterium tuberculosis SSB varies in quaternary structure from E. coli SSB. It forms a dimer of dimers having a unique dimer interface, which lends the protein greater stability. Included in this group are OB folds similar to Escherichia coli PriB. E.coli PriB is homodimeric with each monomer having a single OB fold. It does not appear to form higher order oligomers. PriB is an essential protein for the replication restart at forks that have stalled at sites of DNA damage. It also plays a role in the assembly of primosome during replication initiation at the bacteriophage phiX174 origin. PriB physically interacts with SSB and binds ssDNA with high affinity.


Pssm-ID: 239942  Cd Length: 100  Bit Score: 89.98  E-value: 5.17e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374  57 VELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGTTlDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLHYSGG 136
Cdd:cd04496   1 VILIGRLGKDPELRYTPSGTPVARFSLAVNRRRKDRDEEE-EETDWIRVVAFGKLAENAAKYLKKGDLVYVEGRLRTRSW 79

                        90       100
                ....*....|....*....|...
gi 17554374 137 QKDEQGNRTQrnTYIIAQTVQPL 159
Cdd:cd04496  80 EDKDGQKRYG--TEVVADRIEFL 100
Ssb COG0629
Single-stranded DNA-binding protein [Replication, recombination and repair];
54-169 5.34e-24

Single-stranded DNA-binding protein [Replication, recombination and repair];


Pssm-ID: 440394  Cd Length: 116  Bit Score: 90.28  E-value: 5.34e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374  54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLHY 133
Cdd:COG0629   1 MNKVTLVGRLGKDPELRYTPSGTAVANFRLAVNRRYKDQDGEWKDETDWHRVVAWGKLAENAAEYLKKGDKVYVEGRLRT 80

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 17554374 134 SGGQkDEQGNRTQRnTYIIAQTVQPLARAARENPDQ 169
Cdd:COG0629  81 RSWE-DKDGQKRYT-TEVVADEIQFLGSRPSGGGGG 114
ssb TIGR00621
single stranded DNA-binding protein (ssb); All proteins in this family for which functions are ...
 53-159 2.66e-19

single stranded DNA-binding protein (ssb); All proteins in this family for which functions are known are single-stranded DNA binding proteins that function in many processes including transcription, repair, replication and recombination. Members encoded between genes for ribosomal proteins S6 and S18 should be annotated as primosomal protein N (PriB). Forms in gamma-protoeobacteria are much shorter and poorly recognized by this model. Additional members of this family include phage proteins. Eukaryotic members are organellar proteins. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273179 [Multi-domain]  Cd Length: 164  Bit Score: 79.77  E-value: 2.66e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374    53 SVNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLH 132
Cdd:TIGR00621   3 MVNKVILVGRLTRDPELRYTPSGNAVANFTLATNRRWKDQDGEWKEETEWHDIVIFGRLAEVAAQYLKKGSLVYVEGRLR 82

                          90       100
                  ....*....|....*....|....*..
gi 17554374   133 YSGGQkDEQGNRTQRnTYIIAQTVQPL 159
Cdd:TIGR00621  83 TRKWE-DQNGQKRSK-TEIIADNVQLL 107
PRK05733 PRK05733
single-stranded DNA-binding protein; Provisional
 51-170 4.68e-12

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235585 [Multi-domain]  Cd Length: 172  Bit Score: 60.71  E-value: 4.68e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   51 AYSVNKVELVGGVALDPLYKTGRNGkpylifNIITN-------SYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGS 123
Cdd:PRK05733   2 ARGVNKVILVGTCGQDPEVRYLPNG------NAVTNlslatseQWTDKQSGQKVERTEWHRVSLFGKVAEIAGEYLRKGS 75

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 17554374  124 RLMVQGRLHYSGGQKDEQGNRTQRNTYIIAQTVQPLARAArENPDQH 170
Cdd:PRK05733  76 QVYIEGKLQTREWEKDGIKRYTTEIVVDMQGTMQLLGGRP-QGDDQG 121
PRK06958 PRK06958
single-stranded DNA-binding protein; Provisional
 53-159 4.04e-11

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180777 [Multi-domain]  Cd Length: 182  Bit Score: 58.65  E-value: 4.04e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   53 SVNKVELVGGVALDPLYKTGRNGKPylIFNI---ITNSYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQG 129
Cdd:PRK06958   3 SVNKVILVGNLGADPEVRYLPSGDA--VANIrlaTTDRYKDKASGEFKEATEWHRVAFFGRLAEIVGEYLKKGSSVYIEG 80

                         90       100       110
                 ....*....|....*....|....*....|
gi 17554374  130 RLHYSGGQkdEQGNRTQRNTYIIAQTVQPL 159
Cdd:PRK06958  81 RIRTRKWQ--GQDGQDRYSTEIVADQMQML 108
PRK08763 PRK08763
single-stranded DNA-binding protein; Provisional
 51-159 1.50e-10

single-stranded DNA-binding protein; Provisional


Pssm-ID: 181549 [Multi-domain]  Cd Length: 164  Bit Score: 56.49  E-value: 1.50e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   51 AYSVNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGR 130
Cdd:PRK08763   2 ARGINKVILVGNLGNDPDIKYTQSGMTITRISLATTSVRKDREGNTQERTEWHRVKFFGKLGEIAGEYLRKGSQCYIEGS 81

                         90       100
                 ....*....|....*....|....*....
gi 17554374  131 LHYSggQKDEQGNRTQRNTYIIAQTVQPL 159
Cdd:PRK08763  82 IRYD--KFTGQDGQERYVTEIVADEMQML 108
PRK08486 PRK08486
single-stranded DNA-binding protein; Provisional
 55-159 2.97e-10

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236275 [Multi-domain]  Cd Length: 182  Bit Score: 56.01  E-value: 2.97e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   55 NKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLHYS 134
Cdd:PRK08486   3 NKVILVGNLTRDVELRYLPSGSAIATIGLATSRRFKKQDGEKGEEVCFIDIRLFGRTAEIANQYLSKGSKVLIEGRLTFE 82

                         90       100
                 ....*....|....*....|....*
gi 17554374  135 GGQkDEQGNRTQRNTyIIAQTVQPL 159
Cdd:PRK08486  83 SWM-DQNGQKRSKHT-ITAESMQML 105
PRK13732 PRK13732
single-stranded DNA-binding protein; Provisional
 54-166 7.75e-10

single-stranded DNA-binding protein; Provisional


Pssm-ID: 184284 [Multi-domain]  Cd Length: 175  Bit Score: 55.12  E-value: 7.75e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITN-SYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLH 132
Cdd:PRK13732   6 INKVILVGRLGKDPEVRYIPNGGAVANLQVATSeSWRDKQTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLR 85

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 17554374  133 ysgGQKDEQGNRTQRNTYIIAQ---TVQPLARAAREN 166
Cdd:PRK13732  86 ---TRSWEDNGITRYVTEILVKttgTMQMLGRAPQQN 119
PRK06341 PRK06341
single-stranded DNA-binding protein; Provisional
 51-143 3.63e-08

single-stranded DNA-binding protein; Provisional


Pssm-ID: 235782 [Multi-domain]  Cd Length: 166  Bit Score: 50.19  E-value: 3.63e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   51 AYSVNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQD-GTTLDQTERHAVSVFGKQ-AEILSKTIKKGSRLMVQ 128
Cdd:PRK06341   2 AGSVNKVILIGNLGADPEIRRTQDGRPIANLRIATSETWRDRNsGERKEKTEWHRVVIFNEGlCKVAEQYLKKGAKVYIE 81

                         90
                 ....*....|....*
gi 17554374  129 GRLHYSGGQkDEQGN 143
Cdd:PRK06341  82 GQLQTRKWT-DQSGV 95
PRK09010 PRK09010
single-stranded DNA-binding protein; Provisional
 54-131 4.64e-08

single-stranded DNA-binding protein; Provisional


Pssm-ID: 236362 [Multi-domain]  Cd Length: 177  Bit Score: 50.23  E-value: 4.64e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17554374   54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITN-SYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRL 131
Cdd:PRK09010   6 VNKVILVGNLGQDPEVRYMPNGGAVANITLATSeSWRDKQTGEMKEQTEWHRVVLFGKLAEVAGEYLRKGSQVYIEGQL 84
PRK06863 PRK06863
single-stranded DNA-binding protein; Provisional
 54-131 6.20e-07

single-stranded DNA-binding protein; Provisional


Pssm-ID: 136097 [Multi-domain]  Cd Length: 168  Bit Score: 46.88  E-value: 6.20e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17554374   54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITN-SYFKQQDGTTLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRL 131
Cdd:PRK06863   4 INKVIIVGHLGNDPEIRTMPNGEAVANISVATSeSWTDKNTGERREVTEWHRIVFYRRQAEVAGEYLRKGSQVYVEGRL 82
PRK06642 PRK06642
single-stranded DNA-binding protein; Provisional
 51-132 1.52e-06

single-stranded DNA-binding protein; Provisional


Pssm-ID: 135984  Cd Length: 152  Bit Score: 45.48  E-value: 1.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   51 AYSVNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQ-DGTTLDQTERHAVSVFGKQ-AEILSKTIKKGSRLMVQ 128
Cdd:PRK06642   2 AGSLNKVILIGNVGRDPEIRTTGEGKKIINLSLATTETWKDRiTSERKERTEWHRVVIFSEGlVSVVERYVTKGSKLYIE 81


                 ....
gi 17554374  129 GRLH 132
Cdd:PRK06642  82 GSLQ 85
PRK06752 PRK06752
single-stranded DNA-binding protein; Validated
 54-169 5.02e-06

single-stranded DNA-binding protein; Validated


Pssm-ID: 168660  Cd Length: 112  Bit Score: 43.48  E-value: 5.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   54 VNKVELVGGVALDP-LYKTgRNGKPYLIFNIITNSYFKQQDGTtlDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLH 132
Cdd:PRK06752   2 MNRVVLIGRLTKEPeLYYT-KQGVAYARVCVAVNRGFRNSLGE--QQVDFINCVVWRKSAENVTEYCTKGSLVGITGRIH 78

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 17554374  133 YSgGQKDEQGNRTQRnTYIIAQTVQPLARaARENPDQ 169
Cdd:PRK06752  79 TR-NYEDDQGKRIYI-TEVVIESITFLER-RREGASQ 112
PRK07275 PRK07275
single-stranded DNA-binding protein; Provisional
 54-165 2.21e-05

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180915 [Multi-domain]  Cd Length: 162  Bit Score: 42.57  E-value: 2.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGttldqtERHA----VSVFGKQAEILSKTIKKGSRLMVQG 129
Cdd:PRK07275   2 INNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNG------EREAdfinCVIWRQQAENLANWAKKGALIGVTG 75

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 17554374  130 RLHySGGQKDEQGNRTQRnTYIIAQTVQPL-ARAARE 165
Cdd:PRK07275  76 RIQ-TRNYENQQGQRVYV-TEVVADNFQMLeSRATRE 110
PRK06751 PRK06751
single-stranded DNA-binding protein; Provisional
 54-159 6.11e-05

single-stranded DNA-binding protein; Provisional


Pssm-ID: 168659 [Multi-domain]  Cd Length: 173  Bit Score: 41.32  E-value: 6.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374   54 VNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQQDGttldqtERHA----VSVFGKQAEILSKTIKKGSRLMVQG 129
Cdd:PRK06751   2 MNRVILVGRLTKDPDLRYTPNGVAVATFTLAVNRAFANQQG------EREAdfinCVIWRKQAENVANYLKKGSLAGVDG 75

                         90       100       110
                 ....*....|....*....|....*....|...
gi 17554374  130 RL---HYSGgqkdeQGNRTQRNTYIIAQTVQPL 159
Cdd:PRK06751  76 RLqtrNYEG-----QDGKRVYVTEVLAESVQFL 103
DnaE_OBF cd04485
DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding ...
 70-167 1.47e-03

DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains two copies of this replicative polymerase, each of which copies a different DNA strand. This group also contains Bacillus subtilis DnaE. Replication in B. subtilis and Staphylococcus aureus requires two different type C polymerases, polC and DnaE, both of which are thought to be included in the DNA polymerase holoenzyme. At the B. subtilis replication fork, polC appears to be involved in leading strand synthesis and DnaE in lagging strand synthesis.


Pssm-ID: 239931 [Multi-domain]  Cd Length: 84  Bit Score: 35.95  E-value: 1.47e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554374  70 KTGRNGKPYLIFNIitnsyfkqqdgttLDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRLhysggQKDEQGNRtqrnt 149
Cdd:cd04485  12 RRTKKGKRMAFVTL-------------EDLTGSIEVVVFPETYEKYRDLLKEDALLLVEGKV-----ERRDGGLR----- 68

                        90
                ....*....|....*...
gi 17554374 150 yIIAQTVQPLArAARENP 167
Cdd:cd04485  69 -LIAERIEDLE-DARERL 84
PRK07459 PRK07459
single-stranded DNA-binding protein; Provisional
 53-131 2.88e-03

single-stranded DNA-binding protein; Provisional


Pssm-ID: 180986  Cd Length: 121  Bit Score: 35.82  E-value: 2.88e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17554374   53 SVNKVELVGGVALDPLYKTGRNGKPYLIFNIITNSYFKQqdgttlDQTERHAVSVFGKQAEILSKTIKKGSRLMVQGRL 131
Cdd:PRK07459   2 SLNSVTLVGRAGRDPEVRYFESGSVVCNLTLAVNRRSRD------DEPDWFNLEIWGKTAQVAADYVKKGSLIGITGSL 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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