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Conserved domains on  [gi|17554098|ref|NP_499836|]
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ShKT domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tyrosinase pfam00264
Common central domain of tyrosinase; This family also contains polyphenol oxidases and some ...
 188-376 3.42e-46

Common central domain of tyrosinase; This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.


:

Pssm-ID: 425566  Cd Length: 209  Bit Score: 163.02  E-value: 3.42e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554098   188 YDRLSRQHLEVGVGSGAHSGPGFLPWHREYLKRVEIALR----MVDPTVFIPYWDSVMDSYLPD--PRDSIMFSDLFVGG 261
Cdd:pfam00264   4 YDDFAAIHGIPFTPWPIHGNGLFLPWHRYYLLLFEQALReecgYADPTGTLPYWDWTDDPTSPGisSPTSLGGNGTFIPP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554098   262 TDYYGNVVTGPFAYWRT-IEGRSTILRN----LGAEGQLFNENQVNTIVAQNTIENTLAYTAPQP----------GCPYP 326
Cdd:pfam00264  84 NGGVGEVTNGPFANYTVpNLGPHTIRRPpdnaLAYNPRCLTRDNPLLKQQLNTLDVVDDLLTYQPdytsfsntleGDGGN 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 17554098   327 NNYGAieysHSNIHLWIGGDMKPPSTSANEPIFFMHHSFVDYLWELWRQL 376
Cdd:pfam00264 164 EEGLP----HNGVHVWVGGDMGDVFTAPNDPIFFLHHANIDRLWAIWQRL 209
ShKT smart00254
ShK toxin domain; ShK toxin domain
 586-621 2.53e-05

ShK toxin domain; ShK toxin domain


:

Pssm-ID: 214586 [Multi-domain]  Cd Length: 33  Bit Score: 41.60  E-value: 2.53e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 17554098    586 CMDRHVNCVAWKADkMCSgkSADFMSENCRSSCGKC 621
Cdd:smart00254   1 CVDRHPDCAAWAKG-FCT--NPFYMKSNCPKTCGFC 33
ShK pfam01549
ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 ...
 541-576 3.93e-05

ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 amino acids long and rich in cysteine residues. There are 6 conserved cysteine positions in the domain that form three disulphide bridges. The domain is found in the potassium channel inhibitor ShK in sea anemone.


:

Pssm-ID: 426319  Cd Length: 37  Bit Score: 41.23  E-value: 3.93e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 17554098   541 DCYNRMPCCDSWAKNGgCQREP--EFMSQYCQASCNTC 576
Cdd:pfam01549   1 SCVDPHSDCASWAALG-CTSPFyqDFMKENCPKTCGFC 37
 
Name Accession Description Interval E-value
Tyrosinase pfam00264
Common central domain of tyrosinase; This family also contains polyphenol oxidases and some ...
 188-376 3.42e-46

Common central domain of tyrosinase; This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.


Pssm-ID: 425566  Cd Length: 209  Bit Score: 163.02  E-value: 3.42e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554098   188 YDRLSRQHLEVGVGSGAHSGPGFLPWHREYLKRVEIALR----MVDPTVFIPYWDSVMDSYLPD--PRDSIMFSDLFVGG 261
Cdd:pfam00264   4 YDDFAAIHGIPFTPWPIHGNGLFLPWHRYYLLLFEQALReecgYADPTGTLPYWDWTDDPTSPGisSPTSLGGNGTFIPP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554098   262 TDYYGNVVTGPFAYWRT-IEGRSTILRN----LGAEGQLFNENQVNTIVAQNTIENTLAYTAPQP----------GCPYP 326
Cdd:pfam00264  84 NGGVGEVTNGPFANYTVpNLGPHTIRRPpdnaLAYNPRCLTRDNPLLKQQLNTLDVVDDLLTYQPdytsfsntleGDGGN 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 17554098   327 NNYGAieysHSNIHLWIGGDMKPPSTSANEPIFFMHHSFVDYLWELWRQL 376
Cdd:pfam00264 164 EEGLP----HNGVHVWVGGDMGDVFTAPNDPIFFLHHANIDRLWAIWQRL 209
ShKT smart00254
ShK toxin domain; ShK toxin domain
 586-621 2.53e-05

ShK toxin domain; ShK toxin domain


Pssm-ID: 214586 [Multi-domain]  Cd Length: 33  Bit Score: 41.60  E-value: 2.53e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 17554098    586 CMDRHVNCVAWKADkMCSgkSADFMSENCRSSCGKC 621
Cdd:smart00254   1 CVDRHPDCAAWAKG-FCT--NPFYMKSNCPKTCGFC 33
ShK pfam01549
ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 ...
 586-621 2.60e-05

ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 amino acids long and rich in cysteine residues. There are 6 conserved cysteine positions in the domain that form three disulphide bridges. The domain is found in the potassium channel inhibitor ShK in sea anemone.


Pssm-ID: 426319  Cd Length: 37  Bit Score: 41.61  E-value: 2.60e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 17554098   586 CMDRHVNCVAWKADKMCSGKSADFMSENCRSSCGKC 621
Cdd:pfam01549   2 CVDPHSDCASWAALGCTSPFYQDFMKENCPKTCGFC 37
ShK pfam01549
ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 ...
 541-576 3.93e-05

ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 amino acids long and rich in cysteine residues. There are 6 conserved cysteine positions in the domain that form three disulphide bridges. The domain is found in the potassium channel inhibitor ShK in sea anemone.


Pssm-ID: 426319  Cd Length: 37  Bit Score: 41.23  E-value: 3.93e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 17554098   541 DCYNRMPCCDSWAKNGgCQREP--EFMSQYCQASCNTC 576
Cdd:pfam01549   1 SCVDPHSDCASWAALG-CTSPFyqDFMKENCPKTCGFC 37
ShKT smart00254
ShK toxin domain; ShK toxin domain
 542-576 2.01e-04

ShK toxin domain; ShK toxin domain


Pssm-ID: 214586 [Multi-domain]  Cd Length: 33  Bit Score: 38.90  E-value: 2.01e-04
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 17554098    542 CYNRMPCCDSWAKnGGCQRePEFMSQYCQASCNTC 576
Cdd:smart00254   1 CVDRHPDCAAWAK-GFCTN-PFYMKSNCPKTCGFC 33
 
Name Accession Description Interval E-value
Tyrosinase pfam00264
Common central domain of tyrosinase; This family also contains polyphenol oxidases and some ...
 188-376 3.42e-46

Common central domain of tyrosinase; This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam00372.


Pssm-ID: 425566  Cd Length: 209  Bit Score: 163.02  E-value: 3.42e-46
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554098   188 YDRLSRQHLEVGVGSGAHSGPGFLPWHREYLKRVEIALR----MVDPTVFIPYWDSVMDSYLPD--PRDSIMFSDLFVGG 261
Cdd:pfam00264   4 YDDFAAIHGIPFTPWPIHGNGLFLPWHRYYLLLFEQALReecgYADPTGTLPYWDWTDDPTSPGisSPTSLGGNGTFIPP 83

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554098   262 TDYYGNVVTGPFAYWRT-IEGRSTILRN----LGAEGQLFNENQVNTIVAQNTIENTLAYTAPQP----------GCPYP 326
Cdd:pfam00264  84 NGGVGEVTNGPFANYTVpNLGPHTIRRPpdnaLAYNPRCLTRDNPLLKQQLNTLDVVDDLLTYQPdytsfsntleGDGGN 163

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 17554098   327 NNYGAieysHSNIHLWIGGDMKPPSTSANEPIFFMHHSFVDYLWELWRQL 376
Cdd:pfam00264 164 EEGLP----HNGVHVWVGGDMGDVFTAPNDPIFFLHHANIDRLWAIWQRL 209
ShKT smart00254
ShK toxin domain; ShK toxin domain
 586-621 2.53e-05

ShK toxin domain; ShK toxin domain


Pssm-ID: 214586 [Multi-domain]  Cd Length: 33  Bit Score: 41.60  E-value: 2.53e-05
                           10        20        30
                   ....*....|....*....|....*....|....*.
gi 17554098    586 CMDRHVNCVAWKADkMCSgkSADFMSENCRSSCGKC 621
Cdd:smart00254   1 CVDRHPDCAAWAKG-FCT--NPFYMKSNCPKTCGFC 33
ShK pfam01549
ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 ...
 586-621 2.60e-05

ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 amino acids long and rich in cysteine residues. There are 6 conserved cysteine positions in the domain that form three disulphide bridges. The domain is found in the potassium channel inhibitor ShK in sea anemone.


Pssm-ID: 426319  Cd Length: 37  Bit Score: 41.61  E-value: 2.60e-05
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 17554098   586 CMDRHVNCVAWKADKMCSGKSADFMSENCRSSCGKC 621
Cdd:pfam01549   2 CVDPHSDCASWAALGCTSPFYQDFMKENCPKTCGFC 37
ShK pfam01549
ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 ...
 541-576 3.93e-05

ShK domain-like; This domain of is found in several C. elegans proteins. The domain is 30 amino acids long and rich in cysteine residues. There are 6 conserved cysteine positions in the domain that form three disulphide bridges. The domain is found in the potassium channel inhibitor ShK in sea anemone.


Pssm-ID: 426319  Cd Length: 37  Bit Score: 41.23  E-value: 3.93e-05
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 17554098   541 DCYNRMPCCDSWAKNGgCQREP--EFMSQYCQASCNTC 576
Cdd:pfam01549   1 SCVDPHSDCASWAALG-CTSPFyqDFMKENCPKTCGFC 37
ShKT smart00254
ShK toxin domain; ShK toxin domain
 542-576 2.01e-04

ShK toxin domain; ShK toxin domain


Pssm-ID: 214586 [Multi-domain]  Cd Length: 33  Bit Score: 38.90  E-value: 2.01e-04
                           10        20        30
                   ....*....|....*....|....*....|....*
gi 17554098    542 CYNRMPCCDSWAKnGGCQRePEFMSQYCQASCNTC 576
Cdd:smart00254   1 CVDRHPDCAAWAK-GFCTN-PFYMKSNCPKTCGFC 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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