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Conserved domains on  [gi|71996519|ref|NP_499878|]
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COP9 signalosome complex subunit 3 [Caenorhabditis elegans]

Protein Classification

PCI domain-containing protein( domain architecture ID 10476698)

PCI (proteasome-COP9/CSN-initiation factor) domain-containing protein is a component of multiprotein complexes; similar to Homo sapiens 26S proteasome non-ATPase regulatory subunit 13 and COP9 signalosome complex subunit 3

CATH:  1.25.40.250
Gene Ontology:  GO:0006511
PubMed:  9644972

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 338-432 6.09e-11

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


:

Pssm-ID: 460195  Cd Length: 105  Bit Score: 59.15  E-value: 6.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996519   338 KQFSEIRFSRSSNTHSAVESLVKS-AKDRLRKDGNTEIAKYLVVEMKKKTIMSLTRMFTSIRISEIEELAFLkSRDQVTE 416
Cdd:pfam01399   1 PAYRDLLRAFYSGDLSEFEEILADyKEELLLDDGLAEHLEDLRRKIREHNLRQLSKPYSSISLSDLAKLLGL-SVDEVEK 79

                          90
                  ....*....|....*.
gi 71996519   417 LIGQLVEEQRITVRID 432
Cdd:pfam01399  80 ILAKLIRDGRIRAKID 95
 
Name Accession Description Interval E-value
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 338-432 6.09e-11

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


Pssm-ID: 460195  Cd Length: 105  Bit Score: 59.15  E-value: 6.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996519   338 KQFSEIRFSRSSNTHSAVESLVKS-AKDRLRKDGNTEIAKYLVVEMKKKTIMSLTRMFTSIRISEIEELAFLkSRDQVTE 416
Cdd:pfam01399   1 PAYRDLLRAFYSGDLSEFEEILADyKEELLLDDGLAEHLEDLRRKIREHNLRQLSKPYSSISLSDLAKLLGL-SVDEVEK 79

                          90
                  ....*....|....*.
gi 71996519   417 LIGQLVEEQRITVRID 432
Cdd:pfam01399  80 ILAKLIRDGRIRAKID 95
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 377-432 3.59e-04

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 39.53  E-value: 3.59e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 71996519    377 YLVVEMKKKTIMSLTRMFTSIRISEIEELAFLkSRDQVTELIGQLVEEQRITVRID 432
Cdd:smart00088   5 RLQRKIRLTNLLQLSEPYSSISLSDLAKLLGL-SVPEVEKLVSKAIRDGEISAKID 59
 
Name Accession Description Interval E-value
PCI pfam01399
PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and ...
 338-432 6.09e-11

PCI domain; This domain has also been called the PINT motif (Proteasome, Int-6, Nip-1 and TRIP-15).


Pssm-ID: 460195  Cd Length: 105  Bit Score: 59.15  E-value: 6.09e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996519   338 KQFSEIRFSRSSNTHSAVESLVKS-AKDRLRKDGNTEIAKYLVVEMKKKTIMSLTRMFTSIRISEIEELAFLkSRDQVTE 416
Cdd:pfam01399   1 PAYRDLLRAFYSGDLSEFEEILADyKEELLLDDGLAEHLEDLRRKIREHNLRQLSKPYSSISLSDLAKLLGL-SVDEVEK 79

                          90
                  ....*....|....*.
gi 71996519   417 LIGQLVEEQRITVRID 432
Cdd:pfam01399  80 ILAKLIRDGRIRAKID 95
PINT smart00088
motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, ...
 377-432 3.59e-04

motif in proteasome subunits, Int-6, Nip-1 and TRIP-15; Also called the PCI (Proteasome, COP9, Initiation factor 3) domain. Unknown function.


Pssm-ID: 214509 [Multi-domain]  Cd Length: 88  Bit Score: 39.53  E-value: 3.59e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 71996519    377 YLVVEMKKKTIMSLTRMFTSIRISEIEELAFLkSRDQVTELIGQLVEEQRITVRID 432
Cdd:smart00088   5 RLQRKIRLTNLLQLSEPYSSISLSDLAKLLGL-SVPEVEKLVSKAIRDGEISAKID 59
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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