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Conserved domains on  [gi|17563552|ref|NP_505092|]
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Seven TM Receptor [Caenorhabditis elegans]

Protein Classification

class R serpentine receptor( domain architecture ID 10563422)

class R serpentine receptor, also known as seven TM receptor (Str), belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
6-309 3.46e-102

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402099  Cd Length: 307  Bit Score: 302.84  E-value: 3.46e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552     6 QQTYAHVTFGLSIFSNCLLLSLLLFRSDRNLGSYKYLMFAFSFLGIFFSIVDFLNKPMVHIFGGAYLVF-SLNSLGLPHF 84
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552    85 LANWFNALNCSCYGMTISLLAVHFIYRYLAVCRPNQMSWFMWPHAIVWFLFCSEISFEWWITAVLFAGETTKIDELIKDS 164
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552   165 METNYNLTKGEFIYAASLYYKTDDSGAKAISWPDILFAVNVVKLISICMIIVLFCGISTFRKLRTLRHY-SKRTTNLQNQ 243
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDENGSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLgSEKTRKLQKQ 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17563552   244 LFKALVTQTIIPVVTMFIPAAVMMLAPLFEVTLGSYEVLVMPVITTYPCVDPIVVIFFVKDYRQAI 309
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAI 306
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
6-309 3.46e-102

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 302.84  E-value: 3.46e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552     6 QQTYAHVTFGLSIFSNCLLLSLLLFRSDRNLGSYKYLMFAFSFLGIFFSIVDFLNKPMVHIFGGAYLVF-SLNSLGLPHF 84
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552    85 LANWFNALNCSCYGMTISLLAVHFIYRYLAVCRPNQMSWFMWPHAIVWFLFCSEISFEWWITAVLFAGETTKIDELIKDS 164
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552   165 METNYNLTKGEFIYAASLYYKTDDSGAKAISWPDILFAVNVVKLISICMIIVLFCGISTFRKLRTLRHY-SKRTTNLQNQ 243
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDENGSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLgSEKTRKLQKQ 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17563552   244 LFKALVTQTIIPVVTMFIPAAVMMLAPLFEVTLGSYEVLVMPVITTYPCVDPIVVIFFVKDYRQAI 309
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAI 306
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
6-309 3.46e-102

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 302.84  E-value: 3.46e-102
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552     6 QQTYAHVTFGLSIFSNCLLLSLLLFRSDRNLGSYKYLMFAFSFLGIFFSIVDFLNKPMVHIFGGAYLVF-SLNSLGLPHF 84
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552    85 LANWFNALNCSCYGMTISLLAVHFIYRYLAVCRPNQMSWFMWPHAIVWFLFCSEISFEWWITAVLFAGETTKIDELIKDS 164
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552   165 METNYNLTKGEFIYAASLYYKTDDSGAKAISWPDILFAVNVVKLISICMIIVLFCGISTFRKLRTLRHY-SKRTTNLQNQ 243
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDENGSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLgSEKTRKLQKQ 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17563552   244 LFKALVTQTIIPVVTMFIPAAVMMLAPLFEVTLGSYEVLVMPVITTYPCVDPIVVIFFVKDYRQAI 309
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAI 306
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
1-309 1.11e-32

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 123.51  E-value: 1.11e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552     1 MLLDFQQTYAHVTFG-LSIFSNCLLLSLLLFRSDRNLGSYKYLMFAFSFLGIFFSIVDFLNKPMVHIFGGAYLV------ 73
Cdd:pfam10319   1 MYINWAHYYIPKIFGvLSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVfvsdgp 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552    74 FSLNSLGLPHFLANwfnalNCSCYGMTISLLAVHFIYRYLAVCRPNQMSWFMWPHAIV--WFLFCSEISFeWWITAVLFA 151
Cdd:pfam10319  81 FFEYSELGQHALSA-----RCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFRPWGILisILFFLFHGSV-WTAICYFLL 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552   152 GETTKIDELIKDSMETNYNLTKGEFIYAASLYYKTDDsGAKAISWPDILfAVNVVKLISICMIIVLfcGISTFRKLRTL- 230
Cdd:pfam10319 155 RANDEIRDYIREDFRETYGVDSMDINMLGALYWEASD-ETVFRSWLGIL-LLTVISVYSIILYIVL--GYKIMRKLNKMs 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552   231 RHYSKRTTNLQNQLFKALVTQTIIPVVTMFIPAAVMMLAPLFEVTLGSYEVLV-MPVITTYPCVDPIVVIFFVKDYRQAI 309
Cdd:pfam10319 231 VTMSKKTKRLQKQLLKALIVQTIIPICISFSPCVLAWYSPIFGIDLGRWNNYLeVIALSAFPFIDPLAIILCLPVYRNRI 310
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
4-315 4.86e-11

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 62.56  E-value: 4.86e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552     4 DFQQTYAHVTFGLSIFSNCLLLSLLLFRSDRNLGSYKYLMFAFSFLGIFFSI-VDFLNKPMVH--IFGGAYLVFsLNSLG 80
Cdd:pfam10318   4 DFLSTSLHIITVISIPIHIFGFYCILFKTPKKMKSVKWSLLNLHFWSALLDLsLSFLTIPYIFlpALAGYPLGL-LSYLG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552    81 LPHFLANWFNALNCSCYGMTISLLavhFIYRYLAVCRPNQMSWfmWPHA-IVWFLFCSEISFEWWITAVLFAGEttkIDE 159
Cdd:pfam10318  83 VPTPIQFYIGVTSLALVGVSIILL---FENRYSILFTNKKRIT--WKKTrVLYLIFNYIIALLFLIPIYLNIPD---QEA 154
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552   160 LIKDSMETNYNLTKgEFIYAASLYYKTDDSGakaisWPDILFAVnvvkLISICMIIVLFCGISTFRKLR--TLRHYSKRT 237
Cdd:pfam10318 155 AKLKVLKKLPCLPP-EFFDNPPVFVLAIDST-----YFLICIVL----LILILIIQILFFVFLTIYYLFksVKSSLSKKT 224
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17563552   238 TNLQNQLFKALVTQTIIPVVTMFIPAAVMMLAPLFEVTLGSYEVLVMPVITTYPCVDPIVVIFFVKDYRQAIWQTIRC 315
Cdd:pfam10318 225 RKLQKKFFIALIIQVSIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFKK 302
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
9-309 1.26e-10

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 61.41  E-value: 1.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552     9 YAHVTFGLSIFSNCLLLSLLLFRSDRNLGSYKYLMFAFSFLGIFFSIVDFL--------NKPMVHIFGGAYLVFSlnslg 80
Cdd:pfam10317   4 YYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFtqqriipnGVSMALISYGPCKYFG----- 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552    81 lPHFLANWFNALNCSCYGMTISLLaVHFIYRYLAVCRPNqmswFMWPHAIVWFLFCSEISFEWWITAVLFAGETTKIDEL 160
Cdd:pfam10317  79 -PWFCYSGYSLLQHFLLHSGWSLL-LTFYYRYYILKHVD----PKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEAL 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563552   161 IKDSMEtNYNLTKGEFIYAASLyyktddsgakaISWPDILFAVNVVKLISICMIIVLFCGISTFRKLRTLR-HYSKRTTN 239
Cdd:pfam10317 153 TKELHP-NYNLTDYTVTGFSDL-----------QSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSvNMSPTTKA 220
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17563552   240 LQNQLFKALVTQTIIPVVTmFIPAAVMMLAPLFEVTLGSY-EVLVMPVITTYPCVDPIVVIFFVKDYRQAI 309
Cdd:pfam10317 221 QHRQLIKGLTIQALLPLFS-YIPGVTLYLLSQLTGTEFLIlEYFIFVLPALPPLLDPLITIYFVTPYRRAI 290
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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