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Conserved domains on  [gi|392920384|ref|NP_505705|]
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Serpentine receptor class delta-34 [Caenorhabditis elegans]

Protein Classification

serpentine receptor( domain architecture ID 366230)

serpentine receptor, also known as seven TM receptor (Str), belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srd super family cl22924
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 17-270 1.20e-28

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


The actual alignment was detected with superfamily member pfam10317:

Pssm-ID: 419896  Cd Length: 292  Bit Score: 111.10  E-value: 1.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384   17 ANFFMCIIVVFTQVRPVNNPESSAYLFSGFCRHTHKNACFFSFDFFQLVFDASSFAIPATLFYKYTKVTNINMKnitKNQ 96
Cdd:pfam10317  44 TQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPWFCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPK---RKK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384   97 IRMILLSSYLLSLIVGVIYVITyePDESLEVASETRKFHStQYDFRYYaDITGYQ--KHFWSWLATNLNMISIFVPPIMS 174
Cdd:pfam10317 121 LILLIIIHYIPSLSQLIVIFLS--PTDFLPVEALTKELHP-NYNLTDY-TVTGFSdlQSFPALINTLIMTIPVFPIPIII 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384  175 IVFIRLIQIKLNSLKHLFTDKTAAQAKKFDLALTIQTLVPAVCVIPIYIAHLI--LENYDLPFLSNFekvLYMMLSLPTA 252
Cdd:pfam10317 197 LILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSYIPGVTLYLLsqLTGTEFLILEYF---IFVLPALPPL 273

                         250
                  ....*....|....*...
gi 392920384  253 IDAFIVIVTITPYQKAFI 270
Cdd:pfam10317 274 LDPLITIYFVTPYRRAIL 291
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 17-270 1.20e-28

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 111.10  E-value: 1.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384   17 ANFFMCIIVVFTQVRPVNNPESSAYLFSGFCRHTHKNACFFSFDFFQLVFDASSFAIPATLFYKYTKVTNINMKnitKNQ 96
Cdd:pfam10317  44 TQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPWFCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPK---RKK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384   97 IRMILLSSYLLSLIVGVIYVITyePDESLEVASETRKFHStQYDFRYYaDITGYQ--KHFWSWLATNLNMISIFVPPIMS 174
Cdd:pfam10317 121 LILLIIIHYIPSLSQLIVIFLS--PTDFLPVEALTKELHP-NYNLTDY-TVTGFSdlQSFPALINTLIMTIPVFPIPIII 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384  175 IVFIRLIQIKLNSLKHLFTDKTAAQAKKFDLALTIQTLVPAVCVIPIYIAHLI--LENYDLPFLSNFekvLYMMLSLPTA 252
Cdd:pfam10317 197 LILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSYIPGVTLYLLsqLTGTEFLILEYF---IFVLPALPPL 273

                         250
                  ....*....|....*...
gi 392920384  253 IDAFIVIVTITPYQKAFI 270
Cdd:pfam10317 274 LDPLITIYFVTPYRRAIL 291
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 17-270 1.20e-28

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 111.10  E-value: 1.20e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384   17 ANFFMCIIVVFTQVRPVNNPESSAYLFSGFCRHTHKNACFFSFDFFQLVFDASSFAIPATLFYKYTKVTNINMKnitKNQ 96
Cdd:pfam10317  44 TQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPWFCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPK---RKK 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384   97 IRMILLSSYLLSLIVGVIYVITyePDESLEVASETRKFHStQYDFRYYaDITGYQ--KHFWSWLATNLNMISIFVPPIMS 174
Cdd:pfam10317 121 LILLIIIHYIPSLSQLIVIFLS--PTDFLPVEALTKELHP-NYNLTDY-TVTGFSdlQSFPALINTLIMTIPVFPIPIII 196

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384  175 IVFIRLIQIKLNSLKHLFTDKTAAQAKKFDLALTIQTLVPAVCVIPIYIAHLI--LENYDLPFLSNFekvLYMMLSLPTA 252
Cdd:pfam10317 197 LILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSYIPGVTLYLLsqLTGTEFLILEYF---IFVLPALPPL 273

                         250
                  ....*....|....*...
gi 392920384  253 IDAFIVIVTITPYQKAFI 270
Cdd:pfam10317 274 LDPLITIYFVTPYRRAIL 291
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 143-270 1.01e-03

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 40.13  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392920384  143 YYADITGYQK-HFWSWLATNLNMISIFVPPIMSIVFIRLIQIKLNSLKHLFTDKTAAQAKKFDLALTIQTLVPAVC---- 217
Cdd:pfam10326 180 YPTDENGSKViRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQLFKALVIQTLIPTILmyip 259

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
gi 392920384  218 VIPIYIAHLIleNYDLPFLSNFekvLYMMLSLPTAIDAFIVIVTITPYQKAFI 270
Cdd:pfam10326 260 VGILFLLPLF--NIEIGFLSGI---ITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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