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Conserved domains on  [gi|17564278|ref|NP_505913|]
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Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

Protein Classification

cuticular collagen family protein( domain architecture ID 18387949)

cuticular collagen family protein is a structural macromolecule of the extracellular matrix containing triple helix domains that form tight interactions and stabilize supramolecular aggregates

Gene Ontology:  GO:0042302|GO:0005581
PubMed:  1916105|21421911

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 2.70e-20

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


:

Pssm-ID: 198156  Cd Length: 53  Bit Score: 82.13  E-value: 2.70e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17564278     12 FVAYSAVAFSVVAVLSVCITLPMVHSYVHHVKRTMNQEVQFCRGSAKDIWSEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 84-273 3.46e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.25  E-value: 3.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   84 AGVNGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCDPiTPPPCQPCPQGPPGPPGPPGPSG 163
Cdd:NF038329 170 AGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDG-PAGPAGDGQQGPDGDPGPTGEDG 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  164 DAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQDAPSEPitpgapgpqgapgpqgppgqPGQPGHDGQPG 243
Cdd:NF038329 249 PQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGL--------------------PGKDGKDGQNG 308

                        170       180       190
                 ....*....|....*....|....*....|
gi 17564278  244 APGPKGPNGNPGQPGADGNPGAPGQSGTPG 273
Cdd:NF038329 309 KDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 2.70e-20

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 82.13  E-value: 2.70e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17564278     12 FVAYSAVAFSVVAVLSVCITLPMVHSYVHHVKRTMNQEVQFCRGSAKDIWSEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 15-64 9.49e-18

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 75.19  E-value: 9.49e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 17564278    15 YSAVAFSVVAVLSVCITLPMVHSYVHHVKRTMNQEVQFCRGSAKDIWSEV 64
Cdd:pfam01484   1 YVAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 84-273 3.46e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.25  E-value: 3.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   84 AGVNGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCDPiTPPPCQPCPQGPPGPPGPPGPSG 163
Cdd:NF038329 170 AGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDG-PAGPAGDGQQGPDGDPGPTGEDG 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  164 DAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQDAPSEPitpgapgpqgapgpqgppgqPGQPGHDGQPG 243
Cdd:NF038329 249 PQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGL--------------------PGKDGKDGQNG 308

                        170       180       190
                 ....*....|....*....|....*....|
gi 17564278  244 APGPKGPNGNPGQPGADGNPGAPGQSGTPG 273
Cdd:NF038329 309 KDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 102-279 9.50e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 71.09  E-value: 9.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  102 PGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCDPITPPPCQPCPQGPpgpPGPPgpsGDAGSNGNPGSPGQDGQPG 181
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGP---QGPA---GKDGEAGAKGPAGEKGPQG 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  182 APGNKGPSGQNGNPGAPGAPGQPGQDAPSEPITPGAPGPQGAPGPQGPPGQPGQPGHDGQPGAPGPKGPNGNPGQPGADG 261
Cdd:NF038329 196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                        170
                 ....*....|....*...
gi 17564278  262 NPGAPGQSGTPGGVGEKG 279
Cdd:NF038329 276 KDGERGPVGPAGKDGQNG 293
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 83-279 3.12e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 66.47  E-value: 3.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   83 DAGVNGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGR-----PPQQPCDPITPPPCQPCPQGPPGPPG 157
Cdd:NF038329 148 PAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPrgetgPAGEQGPAGPAGPDGEAGPAGEDGPA 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  158 PPGPSGDAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQDAPSEPItpgapgpqgapgpqgppGQPGQPG 237
Cdd:NF038329 228 GPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPV-----------------GPAGKDG 290

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 17564278  238 HDGQPGAPGPKGP---NGNPGQPGADGNPGAPGQSGTPGGVGEKG 279
Cdd:NF038329 291 QNGKDGLPGKDGKdgqNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 84-250 3.47e-10

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 60.30  E-value: 3.47e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   84 AGVNGGSASAGGCDACCLPGAAGPAGTPGKPGRpGKPGAPGLPGNPGRPPQQPCDPITPPPCQPCPQGPPGPPGPPGPSG 163
Cdd:NF038329 200 TGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGD-GQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDG 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  164 DAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQDAPSepitpgapgpqgapgpqgppGQPGQPGHDGQPG 243
Cdd:NF038329 279 ERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKD--------------------GLPGKDGKDGQPG 338


                 ....*..
gi 17564278  244 APGPKGP 250
Cdd:NF038329 339 KPAPKTP 345
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 86-277 1.03e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.07  E-value: 1.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   86 VNGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQ-QPCDPITPPPCQPCPQGPPGPPGPPGPSGD 164
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAApAEASAAPAPGVAAPEHHPKHVAVPDASDGG 666

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  165 AGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQdAPSEPITPGAPGPQGAPGPQGPPGQPGQPGHDGQPGA 244
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT-PPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEP 745

                        170       180       190
                 ....*....|....*....|....*....|...
gi 17564278  245 PGPKGPNGNPGQPGADGNPGAPGQSGTPGGVGE 277
Cdd:PRK07764 746 DDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSP 778
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 157-206 5.82e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 34.39  E-value: 5.82e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 17564278   157 GPPGPSGDAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQ 206
Cdd:pfam01391   7 GPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
 
Name Accession Description Interval E-value
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 2.70e-20

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 82.13  E-value: 2.70e-20
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 17564278     12 FVAYSAVAFSVVAVLSVCITLPMVHSYVHHVKRTMNQEVQFCRGSAKDIWSEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 15-64 9.49e-18

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 75.19  E-value: 9.49e-18
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 17564278    15 YSAVAFSVVAVLSVCITLPMVHSYVHHVKRTMNQEVQFCRGSAKDIWSEV 64
Cdd:pfam01484   1 YVAVAFSTVAILSSLITLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 84-273 3.46e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 72.25  E-value: 3.46e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   84 AGVNGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCDPiTPPPCQPCPQGPPGPPGPPGPSG 163
Cdd:NF038329 170 AGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDG-PAGPAGDGQQGPDGDPGPTGEDG 248

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  164 DAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQDAPSEPitpgapgpqgapgpqgppgqPGQPGHDGQPG 243
Cdd:NF038329 249 PQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGL--------------------PGKDGKDGQNG 308

                        170       180       190
                 ....*....|....*....|....*....|
gi 17564278  244 APGPKGPNGNPGQPGADGNPGAPGQSGTPG 273
Cdd:NF038329 309 KDGLPGKDGKDGQPGKDGLPGKDGKDGQPG 338
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 102-279 9.50e-14

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 71.09  E-value: 9.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  102 PGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCDPITPPPCQPCPQGPpgpPGPPgpsGDAGSNGNPGSPGQDGQPG 181
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGP---QGPA---GKDGEAGAKGPAGEKGPQG 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  182 APGNKGPSGQNGNPGAPGAPGQPGQDAPSEPITPGAPGPQGAPGPQGPPGQPGQPGHDGQPGAPGPKGPNGNPGQPGADG 261
Cdd:NF038329 196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275

                        170
                 ....*....|....*...
gi 17564278  262 NPGAPGQSGTPGGVGEKG 279
Cdd:NF038329 276 KDGERGPVGPAGKDGQNG 293
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 83-279 3.12e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 66.47  E-value: 3.12e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   83 DAGVNGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGR-----PPQQPCDPITPPPCQPCPQGPPGPPG 157
Cdd:NF038329 148 PAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPrgetgPAGEQGPAGPAGPDGEAGPAGEDGPA 227

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  158 PPGPSGDAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQDAPSEPItpgapgpqgapgpqgppGQPGQPG 237
Cdd:NF038329 228 GPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPV-----------------GPAGKDG 290

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 17564278  238 HDGQPGAPGPKGP---NGNPGQPGADGNPGAPGQSGTPGGVGEKG 279
Cdd:NF038329 291 QNGKDGLPGKDGKdgqNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 84-250 3.47e-10

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 60.30  E-value: 3.47e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   84 AGVNGGSASAGGCDACCLPGAAGPAGTPGKPGRpGKPGAPGLPGNPGRPPQQPCDPITPPPCQPCPQGPPGPPGPPGPSG 163
Cdd:NF038329 200 TGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGD-GQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDG 278

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  164 DAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQDAPSepitpgapgpqgapgpqgppGQPGQPGHDGQPG 243
Cdd:NF038329 279 ERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKD--------------------GLPGKDGKDGQPG 338


                 ....*..
gi 17564278  244 APGPKGP 250
Cdd:NF038329 339 KPAPKTP 345
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 86-277 1.03e-07

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.07  E-value: 1.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   86 VNGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQ-QPCDPITPPPCQPCPQGPPGPPGPPGPSGD 164
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAApAEASAAPAPGVAAPEHHPKHVAVPDASDGG 666

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  165 AGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQdAPSEPITPGAPGPQGAPGPQGPPGQPGQPGHDGQPGA 244
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT-PPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEP 745

                        170       180       190
                 ....*....|....*....|....*....|...
gi 17564278  245 PGPKGPNGNPGQPGADGNPGAPGQSGTPGGVGE 277
Cdd:PRK07764 746 DDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSP 778
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 78-214 5.12e-04

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 41.59  E-value: 5.12e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   78 RQAGYDAGVNGGSASAGGCDACC----LPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRP-PQQPCDPITPPPCQPCPQgp 152
Cdd:PRK14959 372 RPSGGGASAPSGSAAEGPASGGAatipTPGTQGPQGTAPAAGMTPSSAAPATPAPSAAPsPRVPWDDAPPAPPRSGIP-- 449

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17564278  153 pgppgppgpsgdagSNGNPGSPGQDGQPGAPGNKGPSGqnGNPGAPGAPGQPGQDAPSEPIT 214
Cdd:PRK14959 450 --------------PRPAPRMPEASPVPGAPDSVASAS--DAPPTLGDPSDTAEHTPSGPRT 495
PHA03247 PHA03247
large tegument protein UL36; Provisional
 100-275 2.87e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.54  E-value: 2.87e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   100 CLPGAAGPAGTP--GKPGRPGKPGAPGLPGNPGRPPQQPCDPITPPPCQPCPQGPPGPPGPPGPSGDAGSNGNPGSPGQD 177
Cdd:PHA03247 2573 PAPRPSEPAVTSraRRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERP 2652

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   178 GQPGAPGNKGPSGQNGNPGAPGAPGQPGQDAPSEPITPGAPGPQGAPGPQGPPGQPGQPGHDGQPGAPGPKGP----NGN 253
Cdd:PHA03247 2653 RDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPaaarQAS 2732

                         170       180
                  ....*....|....*....|..
gi 17564278   254 PGQPGADGNPGAPGQSGTPGGV 275
Cdd:PHA03247 2733 PALPAAPAPPAVPAGPATPGGP 2754
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 157-206 5.82e-03

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 34.39  E-value: 5.82e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 17564278   157 GPPGPSGDAGSNGNPGSPGQDGQPGAPGNKGPSGQNGNPGAPGAPGQPGQ 206
Cdd:pfam01391   7 GPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 73-212 6.51e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 38.04  E-value: 6.51e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278   73 ANRTARQAGYDAGVNGGSASAGGCDACCLPGAAGPAGTPGKPGRPGKPGAPGLPGNPGRPPQQPCDPITPPPCQPCPQGP 152
Cdd:PRK07764 644 APGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQ 723

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17564278  153 PGPPGPPGPSGDAGSNGNPGSPGQDGQPGAPGNKGPsgqnGNPGAPGAPGQPGQDAPSEP 212
Cdd:PRK07764 724 AAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPP----PPPAPAPAAAPAAAPPPSPP 779
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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