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Conserved domains on  [gi|17567089|ref|NP_510062|]
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Serpentine receptor class delta-40 [Caenorhabditis elegans]

Protein Classification

class D serpentine receptor( domain architecture ID 10563389)

class D serpentine receptor (Srd) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
10-302 3.54e-94

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402094  Cd Length: 292  Bit Score: 280.98  E-value: 3.54e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    10 LYIFYPIFFIFSTITQLMLIYLIFYHSPTHLKMLKVFLLNTSLFQIILVVVSCSSQFRMITTAIPIELRSYGLLRYLEAW 89
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    90 LGYTMYQVLQTSAFMSGMSILITFVFKYELVRQIEFSKSRVTgIILLFHMPIIASMVMEVIMVINQSLPNEIREQYKFLN 169
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLI-LLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPN 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089   170 ANAEEYSIVGALSLKTVPSLINFLLISGSVVASPFISFFFREKILRRINSQFYQHSKWKKSQIQVFVKGLTIQAFLPLIF 249
Cdd:pfam10317 160 YNLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFS 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 17567089   250 YVPVFGLYFYCILTHTEILFQQYFMTVVPCLPAFFDPMLTLYFVTPYRRRLKI 302
Cdd:pfam10317 240 YIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
10-302 3.54e-94

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 280.98  E-value: 3.54e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    10 LYIFYPIFFIFSTITQLMLIYLIFYHSPTHLKMLKVFLLNTSLFQIILVVVSCSSQFRMITTAIPIELRSYGLLRYLEAW 89
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    90 LGYTMYQVLQTSAFMSGMSILITFVFKYELVRQIEFSKSRVTgIILLFHMPIIASMVMEVIMVINQSLPNEIREQYKFLN 169
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLI-LLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPN 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089   170 ANAEEYSIVGALSLKTVPSLINFLLISGSVVASPFISFFFREKILRRINSQFYQHSKWKKSQIQVFVKGLTIQAFLPLIF 249
Cdd:pfam10317 160 YNLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFS 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 17567089   250 YVPVFGLYFYCILTHTEILFQQYFMTVVPCLPAFFDPMLTLYFVTPYRRRLKI 302
Cdd:pfam10317 240 YIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
10-302 3.54e-94

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 280.98  E-value: 3.54e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    10 LYIFYPIFFIFSTITQLMLIYLIFYHSPTHLKMLKVFLLNTSLFQIILVVVSCSSQFRMITTAIPIELRSYGLLRYLEAW 89
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    90 LGYTMYQVLQTSAFMSGMSILITFVFKYELVRQIEFSKSRVTgIILLFHMPIIASMVMEVIMVINQSLPNEIREQYKFLN 169
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLI-LLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPN 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089   170 ANAEEYSIVGALSLKTVPSLINFLLISGSVVASPFISFFFREKILRRINSQFYQHSKWKKSQIQVFVKGLTIQAFLPLIF 249
Cdd:pfam10317 160 YNLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFS 239
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 17567089   250 YVPVFGLYFYCILTHTEILFQQYFMTVVPCLPAFFDPMLTLYFVTPYRRRLKI 302
Cdd:pfam10317 240 YIPGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
10-301 9.74e-07

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 49.38  E-value: 9.74e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    10 LYIFYPIFFIFSTITQLMLIYLIFYHSPTHLKMLKVFLLNTSLFQIILVVVSCSSQ-FRMITTAIPIELRSYGLLRYLEA 88
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKpFIHSYNSSFIVFVDLKDLGLSKS 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    89 WLgyTMYQVLQTSAFMSGMSIL-ITFVFKY-ELVRQIEFSKSRVTGIILLFHMPIIA----SMVMEVIMVINQSLPNEIR 162
Cdd:pfam10326  81 VG--QILLALYCGFYGVSISLLaVQFIYRYlALCRPGKLKYFDGKKLILWFLYPLIFgaiwGLLVYFFLGPDEETDEYLR 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089   163 EQY-KFLNANAEEYSIVGALSLKT---------VPSLINFLLISGSVVASPFISFFFREKILRRINSQFYQHS-KWKKSQ 231
Cdd:pfam10326 159 EELlENYNLDIDEVAYVGPVYYPTdengskvirWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSeKTRKLQ 238
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17567089   232 IQVFvKGLTIQAFLPLIF-YVPVfGLYFYCILTHTEILFQQYFMTVVPCLPAFFDPMLTLYFVTPYRRRLK 301
Cdd:pfam10326 239 KQLF-KALVIQTLIPTILmYIPV-GILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
5-300 4.59e-03

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 38.38  E-value: 4.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089     5 IYRDVLYIFYP-IFFIFSTITQLMLIYLIFYHSPTHLKMLKVFLLNTSLFQIILVVVscssqfrmiTTAIPIELRSYGLL 83
Cdd:pfam10319   1 MYINWAHYYIPkIFGVLSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVV---------ELLVPLDIHSYRYC 71
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089    84 RYL---------EAWLGYTMYQVLQTSAFMSGMSILITFVFKYELVRQIEFSKSR-------VTGIILLFHMpIIASMVM 147
Cdd:pfam10319  72 FVVfvsdgpffeYSELGQHALSARCSFISASYAVLLIHFIYRYLVLFNPQLTRHYfrpwgilISILFFLFHG-SVWTAIC 150
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089   148 EVIMVINQSLPNEIREQY-KFLNANAEEYSIVGAL----SLKTV-PSLINFLLISGSVVASPFISFFFREKILRRINSQF 221
Cdd:pfam10319 151 YFLLRANDEIRDYIREDFrETYGVDSMDINMLGALyweaSDETVfRSWLGILLLTVISVYSIILYIVLGYKIMRKLNKMS 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17567089   222 YQHS-KWKKSQIQVFvKGLTIQAFLPLI---------FYVPVFGLyfyciltHTEILFQQYFMTVVPCLPaFFDPMLTLY 291
Cdd:pfam10319 231 VTMSkKTKRLQKQLL-KALIVQTIIPICisfspcvlaWYSPIFGI-------DLGRWNNYLEVIALSAFP-FIDPLAIIL 301

                  ....*....
gi 17567089   292 FVTPYRRRL 300
Cdd:pfam10319 302 CLPVYRNRI 310
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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