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Conserved domains on  [gi|18410098|ref|NP_567002|]
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histone acetyltransferase of the GNAT family 1 [Arabidopsis thaliana]

Protein Classification

histone acetyltransferase GCN5 family protein( domain architecture ID 13416973)

histone acetyltransferase GCN5 family protein contains a bromodomain, similar to Arabidopsis thaliana GCN5 that acetylates 'Lys-14' of histone H3

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Bromo_gcn5_like cd05509
Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates ...
 459-559 3.20e-52

Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


:

Pssm-ID: 99941 [Multi-domain]  Cd Length: 101  Bit Score: 173.51  E-value: 3.20e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 459 QLNALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEqYYVTLDMFVADARRMFNNCRTYNSP 538
Cdd:cd05509   1 PLYTQLKKVLDSLKNHKSAWPFLEPVDKEEAPDYYDVIKKPMDLSTMEEKLENG-YYVTLEEFVADLKLIFDNCRLYNGP 79

                        90       100
                ....*....|....*....|.
gi 18410098 539 DTIYYKCATRLETHFHSKVQA 559
Cdd:cd05509  80 DTEYYKCANKLEKFFWKKLKE 100
COG5076 super family cl34891
Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin ...
 202-553 1.17e-34

Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription];


The actual alignment was detected with superfamily member COG5076:

Pssm-ID: 227408 [Multi-domain]  Cd Length: 371  Bit Score: 134.55  E-value: 1.17e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 202 IAREEALKREEQAGRLKFVCYSNDSIDEhMMCLIGLKNIFARQLPNMPKEYIVRLLMDRKHKSVMVLRGNL-VVGGITYR 280
Cdd:COG5076  11 LGRPSVLKEEFGNELLRLVDNDSSPFPN-APEEEGSKNLFQKQLKRMPKEYITSIVDDREPGSMANVNDDLeNVGGITYS 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 281 PY-----HSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHA--RDVDGLTHFLTYADNNAVGYFVKQGFTKEIYLEKDVW 353
Cdd:COG5076  90 PFeknrpESLRFDEIVFLAIESVTPESGLGSLLMAHLKTSVkkRKTPKIEDELLYADNKAIAKFKKQLFLRDGRFLSSIF 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 354 HGFIKDYDGGLLMECKIDPklpyTDLSSM---IRQQRKAIDERIRE-----LSNCqnvypkieFLKNEAGIP-RKIIKVE 424
Cdd:COG5076 170 LGLPSKREYPDYYEIIKSP----MDLLTIqkkLKNGRYKSFEEFVSdlnlmFDNC--------KLYNGPDSSvYVDAKEL 237

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 425 EIRGLREAG-WTPDQWGHtRFKLFNGSADMVtNQKQLNAlmrallktMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLK 503
Cdd:COG5076 238 EKYFLKLIEeIPEEMLEL-SIKPGREEREER-ESVLITN--------SQAHVGAWPFLRPVSDEEVPDYYKDIRDPMDLS 307

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|
gi 18410098 504 VIAKRVESEqYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHF 553
Cdd:COG5076 308 TKELKLRNN-YYRPEETFVRDAKLFFDNCVMYNGEVTDYYKNANVLEDFV 356
 
Name Accession Description Interval E-value
Bromo_gcn5_like cd05509
Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates ...
 459-559 3.20e-52

Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99941 [Multi-domain]  Cd Length: 101  Bit Score: 173.51  E-value: 3.20e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 459 QLNALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEqYYVTLDMFVADARRMFNNCRTYNSP 538
Cdd:cd05509   1 PLYTQLKKVLDSLKNHKSAWPFLEPVDKEEAPDYYDVIKKPMDLSTMEEKLENG-YYVTLEEFVADLKLIFDNCRLYNGP 79

                        90       100
                ....*....|....*....|.
gi 18410098 539 DTIYYKCATRLETHFHSKVQA 559
Cdd:cd05509  80 DTEYYKCANKLEKFFWKKLKE 100
BROMO smart00297
bromo domain;
453-553 9.94e-37

bromo domain;


Pssm-ID: 197636 [Multi-domain]  Cd Length: 107  Bit Score: 132.02  E-value: 9.94e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098    453 MVTNQKQLNALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVEsEQYYVTLDMFVADARRMFNNC 532
Cdd:smart00297   1 DPKLQKKLQELLKAVLDKLDSHPLSWPFLKPVSRKEAPDYYDIIKKPMDLKTIKKKLE-NGKYSSVEEFVADFNLMFSNA 79

                           90       100
                   ....*....|....*....|.
gi 18410098    533 RTYNSPDTIYYKCATRLETHF 553
Cdd:smart00297  80 RTYNGPDSEVYKDAKKLEKFF 100
COG5076 COG5076
Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin ...
 202-553 1.17e-34

Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227408 [Multi-domain]  Cd Length: 371  Bit Score: 134.55  E-value: 1.17e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 202 IAREEALKREEQAGRLKFVCYSNDSIDEhMMCLIGLKNIFARQLPNMPKEYIVRLLMDRKHKSVMVLRGNL-VVGGITYR 280
Cdd:COG5076  11 LGRPSVLKEEFGNELLRLVDNDSSPFPN-APEEEGSKNLFQKQLKRMPKEYITSIVDDREPGSMANVNDDLeNVGGITYS 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 281 PY-----HSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHA--RDVDGLTHFLTYADNNAVGYFVKQGFTKEIYLEKDVW 353
Cdd:COG5076  90 PFeknrpESLRFDEIVFLAIESVTPESGLGSLLMAHLKTSVkkRKTPKIEDELLYADNKAIAKFKKQLFLRDGRFLSSIF 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 354 HGFIKDYDGGLLMECKIDPklpyTDLSSM---IRQQRKAIDERIRE-----LSNCqnvypkieFLKNEAGIP-RKIIKVE 424
Cdd:COG5076 170 LGLPSKREYPDYYEIIKSP----MDLLTIqkkLKNGRYKSFEEFVSdlnlmFDNC--------KLYNGPDSSvYVDAKEL 237

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 425 EIRGLREAG-WTPDQWGHtRFKLFNGSADMVtNQKQLNAlmrallktMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLK 503
Cdd:COG5076 238 EKYFLKLIEeIPEEMLEL-SIKPGREEREER-ESVLITN--------SQAHVGAWPFLRPVSDEEVPDYYKDIRDPMDLS 307

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|
gi 18410098 504 VIAKRVESEqYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHF 553
Cdd:COG5076 308 TKELKLRNN-YYRPEETFVRDAKLFFDNCVMYNGEVTDYYKNANVLEDFV 356
Bromodomain pfam00439
Bromodomain; Bromodomains are 110 amino acid long domains, that are found in many chromatin ...
 464-548 5.60e-23

Bromodomain; Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 425683 [Multi-domain]  Cd Length: 84  Bit Score: 92.76  E-value: 5.60e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098   464 MRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYvTLDMFVADARRMFNNCRTYNSPDTIYY 543
Cdd:pfam00439   1 CLEILDKLMEHPIAAPFLEPVDPDEYPDYYSVIKKPMDLSTIKKKLENGEYK-SLAEFLADVKLIFSNARTYNGPGSVIY 79


                  ....*
gi 18410098   544 KCATR 548
Cdd:pfam00439  80 KAAEK 84
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 259-342 3.54e-11

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 60.61  E-value: 3.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098   259 DRKHKSVMVLRGNLVVGGITYRP-YHSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARDVDGLTHFLTYADNN--AVG 335
Cdd:pfam00583  30 DASEGFFVAEEDGELVGFASLSIiDDEPPVGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCERIFLEVAADNlaAIA 109


                  ....*..
gi 18410098   336 YFVKQGF 342
Cdd:pfam00583 110 LYEKLGF 116
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 264-318 2.98e-05

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 41.88  E-value: 2.98e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 18410098 264 SVMVLRGNLVVGGITYRPY-HSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARD 318
Cdd:cd04301   1 FLVAEDDGEIVGFASLSPDgSGGDTAYIGDLAVLPEYRGKGIGSALLEAAEEEARE 56
 
Name Accession Description Interval E-value
Bromo_gcn5_like cd05509
Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates ...
 459-559 3.20e-52

Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99941 [Multi-domain]  Cd Length: 101  Bit Score: 173.51  E-value: 3.20e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 459 QLNALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEqYYVTLDMFVADARRMFNNCRTYNSP 538
Cdd:cd05509   1 PLYTQLKKVLDSLKNHKSAWPFLEPVDKEEAPDYYDVIKKPMDLSTMEEKLENG-YYVTLEEFVADLKLIFDNCRLYNGP 79

                        90       100
                ....*....|....*....|.
gi 18410098 539 DTIYYKCATRLETHFHSKVQA 559
Cdd:cd05509  80 DTEYYKCANKLEKFFWKKLKE 100
BROMO smart00297
bromo domain;
453-553 9.94e-37

bromo domain;


Pssm-ID: 197636 [Multi-domain]  Cd Length: 107  Bit Score: 132.02  E-value: 9.94e-37
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098    453 MVTNQKQLNALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVEsEQYYVTLDMFVADARRMFNNC 532
Cdd:smart00297   1 DPKLQKKLQELLKAVLDKLDSHPLSWPFLKPVSRKEAPDYYDIIKKPMDLKTIKKKLE-NGKYSSVEEFVADFNLMFSNA 79

                           90       100
                   ....*....|....*....|.
gi 18410098    533 RTYNSPDTIYYKCATRLETHF 553
Cdd:smart00297  80 RTYNGPDSEVYKDAKKLEKFF 100
COG5076 COG5076
Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin ...
 202-553 1.17e-34

Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription];


Pssm-ID: 227408 [Multi-domain]  Cd Length: 371  Bit Score: 134.55  E-value: 1.17e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 202 IAREEALKREEQAGRLKFVCYSNDSIDEhMMCLIGLKNIFARQLPNMPKEYIVRLLMDRKHKSVMVLRGNL-VVGGITYR 280
Cdd:COG5076  11 LGRPSVLKEEFGNELLRLVDNDSSPFPN-APEEEGSKNLFQKQLKRMPKEYITSIVDDREPGSMANVNDDLeNVGGITYS 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 281 PY-----HSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHA--RDVDGLTHFLTYADNNAVGYFVKQGFTKEIYLEKDVW 353
Cdd:COG5076  90 PFeknrpESLRFDEIVFLAIESVTPESGLGSLLMAHLKTSVkkRKTPKIEDELLYADNKAIAKFKKQLFLRDGRFLSSIF 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 354 HGFIKDYDGGLLMECKIDPklpyTDLSSM---IRQQRKAIDERIRE-----LSNCqnvypkieFLKNEAGIP-RKIIKVE 424
Cdd:COG5076 170 LGLPSKREYPDYYEIIKSP----MDLLTIqkkLKNGRYKSFEEFVSdlnlmFDNC--------KLYNGPDSSvYVDAKEL 237

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 425 EIRGLREAG-WTPDQWGHtRFKLFNGSADMVtNQKQLNAlmrallktMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLK 503
Cdd:COG5076 238 EKYFLKLIEeIPEEMLEL-SIKPGREEREER-ESVLITN--------SQAHVGAWPFLRPVSDEEVPDYYKDIRDPMDLS 307

                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|
gi 18410098 504 VIAKRVESEqYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHF 553
Cdd:COG5076 308 TKELKLRNN-YYRPEETFVRDAKLFFDNCVMYNGEVTDYYKNANVLEDFV 356
Bromodomain cd04369
Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear ...
 457-557 1.38e-30

Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.


Pssm-ID: 99922 [Multi-domain]  Cd Length: 99  Bit Score: 114.78  E-value: 1.38e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 457 QKQLNALMRALLKTMQDHAdaWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEqYYVTLDMFVADARRMFNNCRTYN 536
Cdd:cd04369   2 KKKLRSLLDALKKLKRDLS--EPFLEPVDPKEAPDYYEVIKNPMDLSTIKKKLKNG-EYKSLEEFEADVRLIFSNAKTYN 78

                        90       100
                ....*....|....*....|.
gi 18410098 537 SPDTIYYKCATRLETHFHSKV 557
Cdd:cd04369  79 GPGSPIYKDAKKLEKLFEKLL 99
Bromo_Acf1_like cd05504
Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was ...
 461-558 2.08e-23

Bromodomain; Acf1_like or BAZ1A_like subfamily. Bromo adjacent to zinc finger 1A (BAZ1A) was identified as a novel human bromodomain gene by cDNA library screening. The Drosophila homologue, Acf1, is part of the CHRAC (chromatin accessibility complex) and regulates ISWI-induced nucleosome remodeling. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99936  Cd Length: 115  Bit Score: 95.15  E-value: 2.08e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 461 NALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYvTLDMFVADARRMFNNCRTYNSPDT 540
Cdd:cd05504  14 LSALEQLLVEIVKHKDSWPFLRPVSKIEVPDYYDIIKKPMDLGTIKEKLNMGEYK-LAEEFLSDIQLVFSNCFLYNPEHT 92

                        90
                ....*....|....*...
gi 18410098 541 IYYKCATRLETHFHSKVQ 558
Cdd:cd05504  93 SVYKAGTRLQRFFIKRCR 110
Bromodomain pfam00439
Bromodomain; Bromodomains are 110 amino acid long domains, that are found in many chromatin ...
 464-548 5.60e-23

Bromodomain; Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 425683 [Multi-domain]  Cd Length: 84  Bit Score: 92.76  E-value: 5.60e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098   464 MRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYvTLDMFVADARRMFNNCRTYNSPDTIYY 543
Cdd:pfam00439   1 CLEILDKLMEHPIAAPFLEPVDPDEYPDYYSVIKKPMDLSTIKKKLENGEYK-SLAEFLADVKLIFSNARTYNGPGSVIY 79


                  ....*
gi 18410098   544 KCATR 548
Cdd:pfam00439  80 KAAEK 84
Bromo_Brdt_I_like cd05497
Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET ...
 455-557 7.10e-23

Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99929  Cd Length: 107  Bit Score: 93.64  E-value: 7.10e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 455 TNQkqLNALMRALLKTMQDHADAWPFKEPVDSR--DVPDYYDIIKDPIDLKVIAKRVESeQYYVTLDMFVADARRMFNNC 532
Cdd:cd05497   3 TNQ--LQYLLKVVLKALWKHKFAWPFQQPVDAVklNLPDYHKIIKTPMDLGTIKKRLEN-NYYWSASECIQDFNTMFTNC 79

                        90       100
                ....*....|....*....|....*
gi 18410098 533 RTYNSPDTIYYKCATRLETHFHSKV 557
Cdd:cd05497  80 YIYNKPGDDVVLMAQTLEKLFLQKL 104
Bromo_BAZ2A_B_like cd05503
Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B ...
 462-540 2.04e-22

Bromodomain, BAZ2A/BAZ2B_like subfamily. Bromo adjacent to zinc finger 2A (BAZ2A) and 2B (BAZ2B) were identified as a novel human bromodomain gene by cDNA library screening. BAZ2A is also known as Tip5 (Transcription termination factor I-interacting protein 5) and hWALp3. The proteins may play roles in transcriptional regulation. Human Tip5 is part of a complex termed NoRC (nucleolar remodeling complex), which induces nucleosome sliding and may play a role in the regulation of the rDNA locus. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99935  Cd Length: 97  Bit Score: 91.67  E-value: 2.04e-22
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18410098 462 ALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQyYVTLDMFVADARRMFNNCRTYNSPDT 540
Cdd:cd05503   3 ALCETILDEMEAHEDAWPFLEPVNTKLVPGYRKIIKKPMDFSTIREKLESGQ-YKTLEEFAEDVRLVFDNCETFNEDDS 80
Bromo_tif1_like cd05502
Bromodomain; tif1_like subfamily. Tif1 (transcription intermediary factor 1) is a member of ...
 474-558 2.06e-21

Bromodomain; tif1_like subfamily. Tif1 (transcription intermediary factor 1) is a member of the tripartite motif (TRIM) protein family, which is characterized by a particular domain architecture. It functions by recruiting coactivators and/or corepressors to modulate transcription. Vertebrate Tif1-gamma, also labeled E3 ubiquitin-protein ligase TRIM33, plays a role in the control of hematopoiesis. Its homologue in Xenopus laevis, Ectodermin, has been shown to function in germ-layer specification and control of cell growth during embryogenesis. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99934 [Multi-domain]  Cd Length: 109  Bit Score: 89.27  E-value: 2.06e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 474 HADAWPFKEPVdSRDVPDYYDIIKDPIDLKVIAKRVE--SEQYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLET 551
Cdd:cd05502  19 HELSLPFHEPV-SPSVPNYYKIIKTPMDLSLIRKKLQpkSPQHYSSPEEFVADVRLMFKNCYKFNEEDSEVAQAGKELEL 97


                ....*..
gi 18410098 552 HFHSKVQ 558
Cdd:cd05502  98 FFEEQLK 104
Bromo_Brdt_II_like cd05498
Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET ...
 468-556 4.03e-21

Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99930  Cd Length: 102  Bit Score: 88.10  E-value: 4.03e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 468 LKTMQDHADAWPFKEPVD--SRDVPDYYDIIKDPIDLKVIAKRVESEQYyVTLDMFVADARRMFNNCRTYNSPDTIYYKC 545
Cdd:cd05498  12 LFSKKHKAYAWPFYKPVDpeALGLHDYHDIIKHPMDLSTIKKKLDNREY-ADAQEFAADVRLMFSNCYKYNPPDHPVHAM 90

                        90
                ....*....|.
gi 18410098 546 ATRLETHFHSK 556
Cdd:cd05498  91 ARKLQDVFEDR 101
Bromo_brd1_like cd05512
Bromodomain; brd1_like subfamily. BRD1 is a mammalian gene which encodes for a nuclear protein ...
 460-549 5.66e-21

Bromodomain; brd1_like subfamily. BRD1 is a mammalian gene which encodes for a nuclear protein assumed to be a transcriptional regulator. BRD1 has been implicated with brain development and susceptibility to schizophrenia and bipolar affective disorder. Bromodomains are 110 amino acid long domains that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99944  Cd Length: 98  Bit Score: 87.84  E-value: 5.66e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 460 LNALMRALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESeQYYVTLDMFVADARRMFNNCRTYNSPD 539
Cdd:cd05512   2 LEVLLRKTLDQLQEKDTAEIFSEPVDLSEVPDYLDHIKQPMDFSTMRKKLES-QRYRTLEDFEADFNLIINNCLAYNAKD 80

                        90
                ....*....|
gi 18410098 540 TIYYKCATRL 549
Cdd:cd05512  81 TIFYRAAVRL 90
Bromo_TFIID cd05511
Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, ...
 476-549 4.14e-19

Bromodomain, TFIID-like subfamily. Human TAFII250 (or TAF250) is the largest subunit of TFIID, a large multi-domain complex, which initiates the assembly of the transcription machinery. TAFII250 contains two bromodomains that specifically bind to acetylated histone H4. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99943 [Multi-domain]  Cd Length: 112  Bit Score: 83.08  E-value: 4.14e-19
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18410098 476 DAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVeSEQYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRL 549
Cdd:cd05511  17 DSWPFHTPVNKKKVPDYYKIIKRPMDLQTIRKKI-SKHKYQSREEFLEDIELIVDNSVLYNGPDSVYTKKAKEM 89
Bromo_BDF1_2_I cd05500
Bromodomain. BDF1/BDF2 like subfamily, restricted to fungi, repeat I. BDF1 and BDF2 are yeast ...
 468-553 6.53e-19

Bromodomain. BDF1/BDF2 like subfamily, restricted to fungi, repeat I. BDF1 and BDF2 are yeast transcription factors involved in the expression of a wide range of genes, including snRNAs; they are required for sporulation and DNA repair and protect histone H4 from deacetylation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99932  Cd Length: 103  Bit Score: 81.98  E-value: 6.53e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 468 LKTMQDhadAWPFKEPVD--SRDVPDYYDIIKDPIDLKVIAKRVESEQYyVTLDMFVADARRMFNNCRTYNSPDTIYYKC 545
Cdd:cd05500  16 LKRLKD---ARPFLVPVDpvKLNIPHYPTIIKKPMDLGTIERKLKSNVY-TSVEEFTADFNLMVDNCLTFNGPEHPVSQM 91


                ....*...
gi 18410098 546 ATRLETHF 553
Cdd:cd05500  92 GKRLQAAF 99
Bromo_plant1 cd05506
Bromodomain, uncharacterized subfamily specific to plants. Might function as a global ...
 466-556 9.13e-19

Bromodomain, uncharacterized subfamily specific to plants. Might function as a global transcription factor. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99938  Cd Length: 99  Bit Score: 81.61  E-value: 9.13e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 466 ALLKTMQDHADAWPFKEPVDSR--DVPDYYDIIKDPIDLKVIAKRVESEQYYVTLDmFVADARRMFNNCRTYNSPDTIYY 543
Cdd:cd05506   7 TLLRKLMKHKWGWVFNAPVDVValGLPDYFDIIKKPMDLGTVKKKLEKGEYSSPEE-FAADVRLTFANAMRYNPPGNDVH 85

                        90
                ....*....|...
gi 18410098 544 KCATRLETHFHSK 556
Cdd:cd05506  86 TMAKELLKIFETR 98
Bromo_BDF1_2_II cd05499
Bromodomain. BDF1/BDF2 like subfamily, restricted to fungi, repeat II. BDF1 and BDF2 are yeast ...
 474-556 2.00e-18

Bromodomain. BDF1/BDF2 like subfamily, restricted to fungi, repeat II. BDF1 and BDF2 are yeast transcription factors involved in the expression of a wide range of genes, including snRNAs; they are required for sporulation and DNA repair and protect histone H4 from deacetylation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99931  Cd Length: 102  Bit Score: 80.79  E-value: 2.00e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 474 HADAWPFKEPVD--SRDVPDYYDIIKDPIDLKVIAKRVESEQYyVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLET 551
Cdd:cd05499  18 SAYNWPFLDPVDpvALNIPNYFSIIKKPMDLGTISKKLQNGQY-QSAKEFERDVRLIFKNCYTFNPEGTDVYMMGHQLEE 96


                ....*
gi 18410098 552 HFHSK 556
Cdd:cd05499  97 VFNDK 101
Bromo_cbp_like cd05495
Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase ...
 460-557 2.87e-17

Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to phosphorylated CREB protein and augments the activity of phosphorylated CREB to activate transcription of cAMP-responsive genes. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99927  Cd Length: 108  Bit Score: 77.48  E-value: 2.87e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 460 LNALMRALLKTMQDHADAWPFKEPVDSR--DVPDYYDIIKDPIDLKVIAKRVESEQYYVTLDmFVADARRMFNNCRTYNS 537
Cdd:cd05495   5 RQALMPTLEKLYKQDPESLPFRQPVDPKllGIPDYFDIVKNPMDLSTIRRKLDTGQYQDPWQ-YVDDVWLMFDNAWLYNR 83

                        90       100
                ....*....|....*....|
gi 18410098 538 PDTIYYKCATRLETHFHSKV 557
Cdd:cd05495  84 KTSRVYKYCTKLAEVFEQEI 103
Bromo_polybromo_V cd05515
Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which ...
 464-550 6.23e-17

Bromodomain, polybromo repeat V. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99946  Cd Length: 105  Bit Score: 76.57  E-value: 6.23e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 464 MRALLKTMQDHAD------AWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQyYVTLDMFVADARRMFNNCRTYNS 537
Cdd:cd05515   5 LWELYNAVKNYTDgrgrrlSLIFMRLPSKSEYPDYYDVIKKPIDMEKIRSKIEGNQ-YQSLDDMVSDFVLMFDNACKYNE 83

                        90
                ....*....|...
gi 18410098 538 PDTIYYKCATRLE 550
Cdd:cd05515  84 PDSQIYKDALTLQ 96
Bromo_SPT7_like cd05510
Bromodomain; SPT7_like subfamily. SPT7 is a yeast protein that functions as a component of the ...
 468-550 1.38e-16

Bromodomain; SPT7_like subfamily. SPT7 is a yeast protein that functions as a component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA, and SLIK. SAGA is involved in the RNA polymerase II-dependent transcriptional regulation of about 10% of all yeast genes. The SPT7 bromodomain has been shown to weakly interact with acetylated histone H3, but not H4. The human representative of this subfamily is cat eye syndrome critical region protein 2 (CECR2). Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99942 [Multi-domain]  Cd Length: 112  Bit Score: 75.56  E-value: 1.38e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 468 LKTMQDHADawPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYVTLDmFVADARRMFNNCRTYNS-PDTIYYKCA 546
Cdd:cd05510  19 LKTYTEHST--PFLTKVSKREAPDYYDIIKKPMDLGTMLKKLKNLQYKSKAE-FVDDLNLIWKNCLLYNSdPSHPLRRHA 95


                ....
gi 18410098 547 TRLE 550
Cdd:cd05510  96 NFMK 99
Bromo_WDR9_I_like cd05529
Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome ...
 428-555 1.25e-15

Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional regulator involved in chromatin remodeling and play a role in embryonic development. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99958  Cd Length: 128  Bit Score: 73.53  E-value: 1.25e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 428 GLREAGWTPDQWG-HTRFKLFNGsADMVTNQKQLNalmrallktmqdhaDAWPFKEPVDSRD-VPDYYDIIKDPIDLKVI 505
Cdd:cd05529  10 ELFDPGWEQPHIRdEERERLISG-LDKLLLSLQLE--------------IAEYFEYPVDLRAwYPDYWNRVPVPMDLETI 74

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|
gi 18410098 506 AKRVESeQYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHFHS 555
Cdd:cd05529  75 RSRLEN-RYYRSLEALRHDVRLILSNAETFNEPNSEIAKKAKRLSDWLLR 123
Bromo_brd7_like cd05513
Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown ...
 457-566 2.99e-15

Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene involved in nasopharyngeal carcinoma. The protein interacts with acetylated histone H3 via its bromodomain. Bromodomains are 110 amino acid long domains that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99945  Cd Length: 98  Bit Score: 71.29  E-value: 2.99e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 457 QKQLNALMRALLKTMQDHADAWPFKEPVdsrdVPDYYDIIKDPIDLKVIAKRVESEQYyVTLDMFVADARRMFNNCRTYN 536
Cdd:cd05513   3 QKALEQLIRQLQRKDPHGFFAFPVTDFI----APGYSSIIKHPMDFSTMKEKIKNNDY-QSIEEFKDDFKLMCENAMKYN 77

                        90       100       110
                ....*....|....*....|....*....|
gi 18410098 537 SPDTIYYKCATRLethfhskvqagLQSGAK 566
Cdd:cd05513  78 KPDTIYYKAAKKL-----------LHSGMK 96
Bromo_SNF2 cd05519
Bromodomain, SNF2-like subfamily, specific to fungi. SNF2 is a yeast protein involved in ...
 457-556 1.21e-14

Bromodomain, SNF2-like subfamily, specific to fungi. SNF2 is a yeast protein involved in transcriptional activation, it is the catalytic component of the SWI/SNF ATP-dependent chromatin remodeling complex. The protein is essential for the regulation of gene expression (both positive and negative) of a large number of genes. The SWI/SNF complex changes chromatin structure by altering DNA-histone contacts within the nucleosome, which results in a re-positioning of the nucleosome and facilitates or represses the binding of gene-specific transcription factors. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99950  Cd Length: 103  Bit Score: 70.06  E-value: 1.21e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 457 QKQLNALMRALLkTMQDHAD---AWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEqYYVTLDMFVADARRMFNNCR 533
Cdd:cd05519   2 KAAMLEIYDAVL-NCEDETGrklSELFLEKPSKKLYPDYYVIIKRPIALDQIKRRIEGR-AYKSLEEFLEDFHLMFANAR 79

                        90       100
                ....*....|....*....|...
gi 18410098 534 TYNSPDTIYYKCATRLETHFHSK 556
Cdd:cd05519  80 TYNQEGSIVYEDAVEMEKAFKKK 102
Bromo_polybromo_III cd05520
Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which ...
 479-557 1.95e-14

Bromodomain, polybromo repeat III. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99951  Cd Length: 103  Bit Score: 69.29  E-value: 1.95e-14
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18410098 479 PFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYvTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHFHSKV 557
Cdd:cd05520  26 PFLKLPSKRKYPDYYQEIKNPISLQQIRTKLKNGEYE-TLEELEADLNLMFENAKRYNVPNSRIYKDAEKLQKLMQAKK 103
Bromo_polybromo_I cd05524
Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which ...
 487-555 7.02e-13

Bromodomain, polybromo repeat I. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99954 [Multi-domain]  Cd Length: 113  Bit Score: 65.05  E-value: 7.02e-13
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18410098 487 RDVPDYYDIIKDPIDLKVIAKRVESEQYyVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHFHS 555
Cdd:cd05524  36 RNEPEYYEVVSNPIDLLKIQQKLKTEEY-DDVDDLTADFELLINNAKAYYKPDSPEHKDACKLWELFLS 103
Bromo_polybromo_IV cd05518
Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which ...
 480-550 7.46e-13

Bromodomain, polybromo repeat IV. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99949 [Multi-domain]  Cd Length: 103  Bit Score: 64.77  E-value: 7.46e-13
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18410098 480 FKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQyYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLE 550
Cdd:cd05518  27 FMEKPSKKDYPDYYKIILEPIDLKTIEHNIRNDK-YATEEELMDDFKLMFRNARHYNEEGSQVYEDANILE 96
Bromo_WSTF_like cd05505
Bromodomain; Williams syndrome transcription factor-like subfamily (WSTF-like). The ...
 467-553 1.81e-12

Bromodomain; Williams syndrome transcription factor-like subfamily (WSTF-like). The Williams-Beuren syndrome deletion transcript 9 is a putative transcriptional regulator. WSTF was found to play a role in vitamin D-mediated transcription as part of two chromatin remodeling complexes, WINAC and WICH. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99937  Cd Length: 97  Bit Score: 63.71  E-value: 1.81e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 467 LLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYvTLDMFVADARRMFNNCRTYNSPDTIYYKCA 546
Cdd:cd05505   8 ILSKILKYRFSWPFREPVTADEAEDYKKVITNPMDLQTMQTKCSCGSYS-SVQEFLDDMKLVFSNAEKYYENGSYVLSCM 86


                ....*..
gi 18410098 547 TRLETHF 553
Cdd:cd05505  87 RKTEQCC 93
Bromo_WDR9_II cd05496
Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome ...
 465-536 2.00e-12

Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional regulator involved in chromatin remodeling and play a role in embryonic development. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99928  Cd Length: 119  Bit Score: 64.02  E-value: 2.00e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18410098 465 RALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYVTLDmFVADARRMFNNCRTYN 536
Cdd:cd05496  11 KELVNLMWDCEDSEPFRQPVDLLKYPDYRDIIDTPMDLGTVKETLFGGNYDDPME-FAKDVRLIFSNSKSYT 81
Bromo_Rsc1_2_II cd05522
Bromodomain, repeat II in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are ...
 479-554 2.43e-12

Bromodomain, repeat II in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are components of the RSC complex (remodeling the structure of chromatin), are essential for transcriptional control, and have a specific domain architecture including two bromodomains. The RSC complex has also been linked to homologous recombination and nonhomologous end-joining repair of DNA double strand breaks. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99953 [Multi-domain]  Cd Length: 104  Bit Score: 63.41  E-value: 2.43e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18410098 479 PFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYvTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHFH 554
Cdd:cd05522  27 HFEKLPDKAREPEYYQEISNPISLDDIKKKVKRRKYK-SFDQFLNDLNLMFENAKLYNENDSQEYKDAVLLEKEAR 101
Bromo_brd8_like cd05507
Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with ...
 462-561 4.58e-12

Bromodomain, brd8_like subgroup. In mammals, brd8 (bromodomain containing 8) interacts with the thyroid hormone receptor in a ligand-dependent fashion and enhances thyroid hormone-dependent activation from thyroid response elements. Brd8 is thought to be a nuclear receptor coactivator. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99939  Cd Length: 104  Bit Score: 62.77  E-value: 4.58e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 462 ALMrALLKTMQDHADAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYvTLDMFVADARRMFNNCRTYNSPDTI 541
Cdd:cd05507   7 AIL-LVYRTLASHRYASVFLKPVTEDIAPGYHSVVYRPMDLSTIKKNIENGTIR-STAEFQRDVLLMFQNAIMYNSSDHD 84

                        90       100
                ....*....|....*....|
gi 18410098 542 YYKCATRLETHFHSKVQAGL 561
Cdd:cd05507  85 VYLMAVEMQREVMSQIQQLL 104
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 259-342 3.54e-11

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 60.61  E-value: 3.54e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098   259 DRKHKSVMVLRGNLVVGGITYRP-YHSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARDVDGLTHFLTYADNN--AVG 335
Cdd:pfam00583  30 DASEGFFVAEEDGELVGFASLSIiDDEPPVGEIEGLAVAPEYRGKGIGTALLQALLEWARERGCERIFLEVAADNlaAIA 109


                  ....*..
gi 18410098   336 YFVKQGF 342
Cdd:pfam00583 110 LYEKLGF 116
Bromo_polybromo_II cd05517
Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which ...
 490-556 9.54e-11

Bromodomain, polybromo repeat II. Polybromo is a nuclear protein of unknown function, which contains 6 bromodomains. The human ortholog BAF180 is part of a SWI/SNF chromatin-remodeling complex, and it may carry out the functions of Yeast Rsc-1 and Rsc-2. It was shown that polybromo bromodomains bind to histone H3 at specific acetyl-lysine positions. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine, but not all the bromodomains in polybromo may bind to acetyl-lysine.


Pssm-ID: 99948  Cd Length: 103  Bit Score: 58.99  E-value: 9.54e-11
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18410098 490 PDYYDIIKDPIDLKVIAKRVESeQYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHFHSK 556
Cdd:cd05517  37 PDYYAVIKEPIDLKTIAQRIQS-GYYKSIEDMEKDLDLMVKNAKTFNEPGSQVYKDANAIKKIFTAK 102
Bromo_SNF2L2 cd05516
Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI ...
 458-543 1.06e-10

Bromodomain, SNF2L2-like subfamily, specific to animals. SNF2L2 (SNF2-alpha) or SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 is a global transcriptional activator, which cooperates with nuclear hormone receptors to boost transcriptional activation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99947  Cd Length: 107  Bit Score: 58.98  E-value: 1.06e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 458 KQLNALMRALLKTMQDHAD--AWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQyYVTLDMFVADARRMFNNCRTY 535
Cdd:cd05516   4 KKMNKIVDVVIKYKDSDGRqlAEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHK-YRSLEDLEKDVMLLCQNAQTF 82


                ....*...
gi 18410098 536 NSPDTIYY 543
Cdd:cd05516  83 NLEGSLIY 90
Bromo_AAA cd05528
Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long ...
 479-540 2.60e-10

Bromodomain; sub-family co-occurring with AAA domains. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine. The structure(2DKW) in this alignment is an uncharacterized protein predicted from analysis of cDNA clones from human fetal liver


Pssm-ID: 99957  Cd Length: 112  Bit Score: 57.75  E-value: 2.60e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18410098 479 PFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQyYVTLDMFVADARRMFNNCRTYNsPDT 540
Cdd:cd05528  23 AFTKPVDEEEVPDYYEIIKQPMDLQTILQKLDTHQ-YLTAKDFLKDIDLIVTNALEYN-PDR 82
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 253-343 7.22e-10

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 57.31  E-value: 7.22e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 253 IVRLLM-----DRKHKSVMVLRGNLVVGGITYRPYhSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARDvDGLTHFLT 327
Cdd:COG1246  14 ILELIRpyaleEEIGEFWVAEEDGEIVGCAALHPL-DEDLAELRSLAVHPDYRGRGIGRRLLEALLAEARE-LGLKRLFL 91

                        90
                ....*....|....*.
gi 18410098 328 YADNNAVGYFVKQGFT 343
Cdd:COG1246  92 LTTSAAIHFYEKLGFE 107
Bromo_Rsc1_2_I cd05521
Bromodomain, repeat I in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are ...
 487-557 2.47e-08

Bromodomain, repeat I in Rsc1/2_like subfamily, specific to fungi. Rsc1 and Rsc2 are components of the RSC complex (remodeling the structure of chromatin), are essential for transcriptional control, and have a specific domain architecture including two bromodomains. The RSC complex has also been linked to homologous recombination and nonhomologous end-joining repair of DNA double strand breaks. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99952  Cd Length: 106  Bit Score: 51.94  E-value: 2.47e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18410098 487 RDVPDYYDIIKDPIDLKVIAKRVeseQYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHFHSKV 557
Cdd:cd05521  35 KDYPDYYKIIKNPLSLNTVKKRL---PHYTNAQEFVNDLAQIPWNARLYNTKGSVIYKYALILEKYINDVI 102
Bromodomain_1 cd05494
Bromodomain; uncharacterized subfamily. Bromodomains are found in many chromatin-associated ...
 462-502 4.54e-07

Bromodomain; uncharacterized subfamily. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.


Pssm-ID: 99926 [Multi-domain]  Cd Length: 114  Bit Score: 48.59  E-value: 4.54e-07
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*
gi 18410098 462 ALMRAL--LKTMQDHADAWPFKEPVD--SRDVPDYYDIIKDPIDL 502
Cdd:cd05494   4 ALERVLreLKRHRRNEDAWPFLEPVNppRRGAPDYRDVIKRPMSF 48
Bromo_RACK7 cd05508
Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) ...
 457-539 4.92e-07

Bromodomain, RACK7_like subfamily. RACK7 (also called human protein kinase C-binding protein) was identified as a potential tumor suppressor genes, it shares domain architecture with BS69/ZMYND11; both have been implicated in the regulation of cellular proliferation. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99940  Cd Length: 99  Bit Score: 48.15  E-value: 4.92e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 457 QKQLNALMRALLKTMQDHAdAWPFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESEQYYVTlDMFVADARRMFNNCRTYN 536
Cdd:cd05508   1 VDQLSKLLKFALERMKQPG-AEPFLKPVDLEQFPDYAQYVFKPMDLSTLEKNVRKKAYGST-DAFLADAKWILHNAIIYN 78


                ...
gi 18410098 537 SPD 539
Cdd:cd05508  79 GGD 81
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 275-371 1.99e-06

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 46.19  E-value: 1.99e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 275 GGITYRPYHSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARDvDGLTH-FLTYADNN--AVGYFVKQGFTKeiylekd 351
Cdd:COG0456   1 GFALLGLVDGGDEAEIEDLAVDPEYRGRGIGRALLEAALERARE-RGARRlRLEVREDNeaAIALYEKLGFEE------- 72

                        90       100
                ....*....|....*....|..
gi 18410098 352 vwHGFIKDY--DGGLLMECKID 371
Cdd:COG0456  73 --VGERPNYygDDALVMEKELA 92
Bromo_ASH1 cd05525
Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the ...
 479-555 5.74e-06

Bromodomain; ASH1_like sub-family. ASH1 (absent, small, or homeotic 1) is a member of the trithorax-group in Drosophila melanogaster, an epigenetic transcriptional regulator of HOX genes. Drosophila ASH1 has been shown to methylate specific lysines in histones H3 and H4. Mammalian ASH1 has been shown to methylate histone H3. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99955 [Multi-domain]  Cd Length: 106  Bit Score: 45.46  E-value: 5.74e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18410098 479 PFKEPVDSRDVPDYYDIIKDPIDLKVIAKRVESeQYYVTLDMFVADARRMFNNCRTYNSPDTIYYKCATRLETHFHS 555
Cdd:cd05525  28 PFINLPSKKKNPDYYERITDPVDLSTIEKQILT-GYYKTPEAFDSDMLKVFRNAEKYYGRKSPIGRDVCRLRKAYYQ 103
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 267-344 1.34e-05

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 43.60  E-value: 1.34e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 18410098   267 VLRGNLVVGGITYRPYHSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARDvDGLTHFLTYADNNAVGYFVKQGFTK 344
Cdd:pfam13508   8 AEDDGKIVGFAALLPLDDEGALAELRLAVHPEYRGQGIGRALLEAAEAAAKE-GGIKLLELETTNRAAAFYEKLGFEE 84
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 264-318 2.98e-05

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 41.88  E-value: 2.98e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 18410098 264 SVMVLRGNLVVGGITYRPY-HSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARD 318
Cdd:cd04301   1 FLVAEDDGEIVGFASLSPDgSGGDTAYIGDLAVLPEYRGKGIGSALLEAAEEEARE 56
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
264-343 3.31e-05

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 43.92  E-value: 3.31e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 264 SVMVLRGNLVVGGITYRPYH---SQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARDvDGLTHFLTYADNNAVGYFVKQ 340
Cdd:COG3153  41 SLVAEDDGEIVGHVALSPVDidgEGPALLLGPLAVDPEYRGQGIGRALMRAALEAARE-RGARAVVLLGDPSLLPFYERF 119


                ...
gi 18410098 341 GFT 343
Cdd:COG3153 120 GFR 122
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
265-354 2.52e-04

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 41.32  E-value: 2.52e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 265 VMVLRGNLVVGGITYRPYhSQKFGEIAFCAITADEQVKGYGTRLMNHLKQHARDvDGLTHFLTYADNNAVGYFVKQGFTK 344
Cdd:COG2153  37 LLAYDDGELVATARLLPP-GDGEAKIGRVAVLPEYRGQGLGRALMEAAIEEARE-RGARRIVLSAQAHAVGFYEKLGFVP 114

                        90
                ....*....|..
gi 18410098 345 --EIYLEKDVWH 354
Cdd:COG2153 115 vgEEFLEAGIPH 126
Bromo_SP100C_like cd05501
Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major ...
 491-539 4.40e-04

Bromodomain, SP100C_like subfamily. The SP100C protein is a splice variant of SP100, a major component of PML-SP100 nuclear bodies (NBs), which are poorly understood. It is covalently modified by SUMO-1 and may play a role in processes at the chromatin level. Bromodomains are 110 amino acid long domains, that are found in many chromatin associated proteins. Bromodomains can interact specifically with acetylated lysine.


Pssm-ID: 99933  Cd Length: 102  Bit Score: 39.72  E-value: 4.40e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|....*....
gi 18410098 491 DYYDIIKDPIDLKVIAKRVESEQYYvTLDMFVADARRMFNNCRTYNSPD 539
Cdd:cd05501  32 DYCQGIKEPMWLNKVKERLNERVYH-TVEGFVRDMRLIFHNHKLFYKDD 79
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 250-355 1.81e-03

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 39.60  E-value: 1.81e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 250 KEYIVRLLMDRKHKSVMVL-----RGNLVVGGITYRPYH-SQKFGEIAFcAITADEQVKGYGTRLMNHLKQHARDVDGLT 323
Cdd:COG1670  45 RAWLERLLADWADGGALPFaiedkEDGELIGVVGLYDIDrANRSAEIGY-WLAPAYWGKGYATEALRALLDYAFEELGLH 123

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 18410098 324 HF--LTYADNNA---VgyFVKQGFTKEIYLEKDVWHG 355
Cdd:COG1670 124 RVeaEVDPDNTAsirV--LEKLGFRLEGTLRDALVID 158
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
259-357 3.58e-03

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 38.44  E-value: 3.58e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18410098 259 DRKHKSVMVLRGNLVVGGITYRPYHS----QKFGEIAFcAITADEQVKGYGTRLMNHLKQHARDvDGLTHFL--TYADN- 331
Cdd:COG1247  49 APGRPVLVAEEDGEVVGFASLGPFRPrpayRGTAEESI-YVDPDARGRGIGRALLEALIERARA-RGYRRLVavVLADNe 126

                        90       100       110
                ....*....|....*....|....*....|.
gi 18410098 332 NAVGYFVKQGFT-----KEIYLEKDVWHGFI 357
Cdd:COG1247 127 ASIALYEKLGFEevgtlPEVGFKFGRWLDLV 157
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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