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Conserved domains on  [gi|18414298|ref|NP_568125|]
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Pyridine nucleotide-disulfide oxidoreductase family protein [Arabidopsis thaliana]

Protein Classification

NAD(P)/FAD-dependent oxidoreductase( domain architecture ID 11441266)

NAD(P)/FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant; belongs to the pyridine nucleotide-disulfide oxidoreductase superfamily

CATH:  3.30.390.30
EC:  1.-.-.-
Gene Ontology:  GO:0016491|GO:0000166
PubMed:  38537870
SCOP:  4000121

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
33-427 1.17e-86

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


:

Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 269.70  E-value: 1.17e-86
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  33 GELAIISREQVPPYERPALSKGyihLENKATLPNFYVAAgiggerqfPQWYKEKGIELILGTEIVKADLAAKTLVSGTGQ 112
Cdd:COG1251  27 GEITVIGAEPHPPYNRPPLSKV---LAGETDEEDLLLRP--------ADFYEENGIDLRLGTRVTAIDRAARTVTLADGE 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 113 VFKYQTLLAATGSSVIRLsdfGVPGADAKNIFYLRELEDADYL-AYAmetKEKGKAVVVGGGYIGLELGAALKANNLDVT 191
Cdd:COG1251  96 TLPYDKLVLATGSRPRVP---PIPGADLPGVFTLRTLDDADALrAAL---APGKRVVVIGGGLIGLEAAAALRKRGLEVT 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 192 MVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTVASGFTtnSNGEVTEVKLKDGRTLEADIVIVGVGGRPIISLFKD 271
Cdd:COG1251 170 VVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIE--GDDRVTGVRLADGEELPADLVVVAIGVRPNTELARA 247

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 272 ---QVEeekGGLKTDGFFKTSLPDVYAIGDVATFPMKLYNEmRRVEHVDHARKSAEQAVKAIKaaeeGNSIPEYDYLPYF 348
Cdd:COG1251 248 aglAVD---RGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGR-RVLELVAPAYEQARVAAANLA----GGPAAYEGSVPST 319

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 349 YSRAFDLSWQFYGDNVG--ESVLFGDndpespkPKFGSY---WIKERKVVGAFLeGGSPEENNAIAKLARAQPSVESLEV 423
Cdd:COG1251 320 KLKVFGVDVASAGDAEGdeEVVVRGD-------PARGVYkklVLRDGRLVGAVL-VGDTSDAGALRQLIKNGRPLPPRAL 391


                ....
gi 18414298 424 LSKE 427
Cdd:COG1251 392 LDAA 395
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
33-427 1.17e-86

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 269.70  E-value: 1.17e-86
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  33 GELAIISREQVPPYERPALSKGyihLENKATLPNFYVAAgiggerqfPQWYKEKGIELILGTEIVKADLAAKTLVSGTGQ 112
Cdd:COG1251  27 GEITVIGAEPHPPYNRPPLSKV---LAGETDEEDLLLRP--------ADFYEENGIDLRLGTRVTAIDRAARTVTLADGE 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 113 VFKYQTLLAATGSSVIRLsdfGVPGADAKNIFYLRELEDADYL-AYAmetKEKGKAVVVGGGYIGLELGAALKANNLDVT 191
Cdd:COG1251  96 TLPYDKLVLATGSRPRVP---PIPGADLPGVFTLRTLDDADALrAAL---APGKRVVVIGGGLIGLEAAAALRKRGLEVT 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 192 MVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTVASGFTtnSNGEVTEVKLKDGRTLEADIVIVGVGGRPIISLFKD 271
Cdd:COG1251 170 VVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIE--GDDRVTGVRLADGEELPADLVVVAIGVRPNTELARA 247

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 272 ---QVEeekGGLKTDGFFKTSLPDVYAIGDVATFPMKLYNEmRRVEHVDHARKSAEQAVKAIKaaeeGNSIPEYDYLPYF 348
Cdd:COG1251 248 aglAVD---RGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGR-RVLELVAPAYEQARVAAANLA----GGPAAYEGSVPST 319

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 349 YSRAFDLSWQFYGDNVG--ESVLFGDndpespkPKFGSY---WIKERKVVGAFLeGGSPEENNAIAKLARAQPSVESLEV 423
Cdd:COG1251 320 KLKVFGVDVASAGDAEGdeEVVVRGD-------PARGVYkklVLRDGRLVGAVL-VGDTSDAGALRQLIKNGRPLPPRAL 391


                ....
gi 18414298 424 LSKE 427
Cdd:COG1251 392 LDAA 395
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 31-323 6.71e-53

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 179.05  E-value: 6.71e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298    31 KPGELAIISREQVPPYERPALSKGYIHlenkatlpnfyVAAGIGGERQFPQWYKEK---------GIELILGTEIVKADL 101
Cdd:pfam07992  22 LGGKVTLIEDEGTCPYGGCVLSKALLG-----------AAEAPEIASLWADLYKRKeevvkklnnGIEVLLGTEVVSIDP 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   102 AAKTL-----VSGTGQVFKYQTLLAATGSSVIRLsdfGVPGADAKNIFYLRELEDADYLAYAmetKEKGKAVVVGGGYIG 176
Cdd:pfam07992  91 GAKKVvleelVDGDGETITYDRLVIATGARPRLP---PIPGVELNVGFLVRTLDSAEALRLK---LLPKRVVVVGGGYIG 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   177 LELGAALKANNLDVTMVYPEPWcMPRLFTAGIASFYEGYYANKGINIVKGTVASGFttNSNGEVTEVKLKDGRTLEADIV 256
Cdd:pfam07992 165 VELAAALAKLGKEVTLIEALDR-LLRAFDEEISAALEKALEKNGVEVRLGTSVKEI--IGDGDGVEVILKDGTEIDADLV 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18414298   257 IVGVGGRPIISLFKDQ-VE-EEKGGLKTDGFFKTSLPDVYAIGDVAtfpmklyneMRRVEHVDHARKSA 323
Cdd:pfam07992 242 VVAIGRRPNTELLEAAgLElDERGGIVVDEYLRTSVPGIYAAGDCR---------VGGPELAQNAVAQG 301
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 33-379 7.63e-33

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 128.12  E-value: 7.63e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   33 GELAIISREQVPPYERPALSKGYihLENKATLPNFYVAAgiggerqfpQWYKEKGIELILGTEIVKADLAAKTLVSGTGQ 112
Cdd:PRK09754  29 GELHLFSDERHLPYERPPLSKSM--LLEDSPQLQQVLPA---------NWWQENNVHLHSGVTIKTLGRDTRELVLTNGE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  113 VFKYQTLLAATGSSVIRLsdfgvPGADA--KNIFYLRELEDADYLAYAMetKEKGKAVVVGGGYIGLELGAALKANNLDV 190
Cdd:PRK09754  98 SWHWDQLFIATGAAARPL-----PLLDAlgERCFTLRHAGDAARLREVL--QPERSVVIVGAGTIGLELAASATQRRCKV 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  191 TMVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTvasGFTTNSNGEVTEVKLKDGRTLEADIVIVGVGGRpiislFK 270
Cdd:PRK09754 171 TVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNN---AIEHVVDGEKVELTLQSGETLQADVVIYGIGIS-----AN 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  271 DQVEEE-----KGGLKTDGFFKTSLPDVYAIGDVATfpMKLYN-EMRRVEHVDHARKSAEQAVKAIKAAEegnsiPEYDY 344
Cdd:PRK09754 243 DQLAREanldtANGIVIDEACRTCDPAIFAGGDVAI--TRLDNgALHRCESWENANNQAQIAAAAMLGLP-----LPLLP 315

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 18414298  345 LPYFYSRAFDLSWQFYGDNVGESVLFgDNDPESPK 379
Cdd:PRK09754 316 PPWFWSDQYSDNLQFIGDMRGDDWLC-RGNPETQK 349
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 34-372 1.71e-31

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 127.64  E-value: 1.71e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298    34 ELAIISREQVPPYERPALSKgyiHLENKATLPNFYVAAGiggerqfpQWYKEKGIELILGTEIVKADLAAKTLVSGTGQV 113
Cdd:TIGR02374  26 EITIFGEEPHPNYNRILLSS---VLQGEADLDDITLNSK--------DWYEKHGITLYTGETVIQIDTDQKQVITDAGRT 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   114 FKYQTLLAATGSSVIRLSdfgVPGADAKNIFYLRELEDADYL-AYAMETKekgKAVVVGGGYIGLELGAALKANNLDVTM 192
Cdd:TIGR02374  95 LSYDKLILATGSYPFILP---IPGADKKGVYVFRTIEDLDAImAMAQRFK---KAAVIGGGLLGLEAAVGLQNLGMDVSV 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   193 VYPEPWCMPRLFTAGIASFYEGYYANKGINIV--KGTVASgfttNSNGEVTEVKLKDGRTLEADIVIVGVGGRPIISLFK 270
Cdd:TIGR02374 169 IHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLleKDTVEI----VGATKADRIRFKDGSSLEADLIVMAAGIRPNDELAV 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   271 DQVEEEKGGLKTDGFFKTSLPDVYAIGDVATFPMKLYN------EMRRVEhVDH-----------ARKSAEQAVKAI--- 330
Cdd:TIGR02374 245 SAGIKVNRGIIVNDSMQTSDPDIYAVGECAEHNGRVYGlvaplyEQAKVL-ADHicgveceeyegSDLSAKLKLLGVdvw 323

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 18414298   331 -----KAAEEGNSIPEYDYLPYFYSRAFdlswqFYGDNVGESVLFGD 372
Cdd:TIGR02374 324 sagdaQETERTTSIKIYDEQKGIYKKLV-----LSDDKLLGAVLFGD 365
 
Name Accession Description Interval E-value
NirB COG1251
NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];
33-427 1.17e-86

NAD(P)H-nitrite reductase, large subunit [Energy production and conversion];


Pssm-ID: 440863 [Multi-domain]  Cd Length: 402  Bit Score: 269.70  E-value: 1.17e-86
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  33 GELAIISREQVPPYERPALSKGyihLENKATLPNFYVAAgiggerqfPQWYKEKGIELILGTEIVKADLAAKTLVSGTGQ 112
Cdd:COG1251  27 GEITVIGAEPHPPYNRPPLSKV---LAGETDEEDLLLRP--------ADFYEENGIDLRLGTRVTAIDRAARTVTLADGE 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 113 VFKYQTLLAATGSSVIRLsdfGVPGADAKNIFYLRELEDADYL-AYAmetKEKGKAVVVGGGYIGLELGAALKANNLDVT 191
Cdd:COG1251  96 TLPYDKLVLATGSRPRVP---PIPGADLPGVFTLRTLDDADALrAAL---APGKRVVVIGGGLIGLEAAAALRKRGLEVT 169

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 192 MVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTVASGFTtnSNGEVTEVKLKDGRTLEADIVIVGVGGRPIISLFKD 271
Cdd:COG1251 170 VVERAPRLLPRQLDEEAGALLQRLLEALGVEVRLGTGVTEIE--GDDRVTGVRLADGEELPADLVVVAIGVRPNTELARA 247

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 272 ---QVEeekGGLKTDGFFKTSLPDVYAIGDVATFPMKLYNEmRRVEHVDHARKSAEQAVKAIKaaeeGNSIPEYDYLPYF 348
Cdd:COG1251 248 aglAVD---RGIVVDDYLRTSDPDIYAAGDCAEHPGPVYGR-RVLELVAPAYEQARVAAANLA----GGPAAYEGSVPST 319

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 349 YSRAFDLSWQFYGDNVG--ESVLFGDndpespkPKFGSY---WIKERKVVGAFLeGGSPEENNAIAKLARAQPSVESLEV 423
Cdd:COG1251 320 KLKVFGVDVASAGDAEGdeEVVVRGD-------PARGVYkklVLRDGRLVGAVL-VGDTSDAGALRQLIKNGRPLPPRAL 391


                ....
gi 18414298 424 LSKE 427
Cdd:COG1251 392 LDAA 395
FadH2 COG0446
NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase ...
 33-362 1.00e-67

NADPH-dependent 2,4-dienoyl-CoA reductase, sulfur reductase, or a related oxidoreductase [Lipid transport and metabolism];


Pssm-ID: 440215 [Multi-domain]  Cd Length: 322  Bit Score: 218.53  E-value: 1.00e-67
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  33 GELAIISREQVPPYERPALSKgyihlenkatlpnfYVAAGIGGERQF----PQWYKEKGIELILGTEIVKADLAAKTLVS 108
Cdd:COG0446   6 AEITVIEKGPHHSYQPCGLPY--------------YVGGGIKDPEDLlvrtPESFERKGIDVRTGTEVTAIDPEAKTVTL 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 109 GTGQVFKYQTLLAATGSSVIRLSdfgVPGADAKNIFYLRELEDADYLAYAMETKEKGKAVVVGGGYIGLELGAALKANNL 188
Cdd:COG0446  72 RDGETLSYDKLVLATGARPRPPP---IPGLDLPGVFTLRTLDDADALREALKEFKGKRAVVIGGGPIGLELAEALRKRGL 148

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 189 DVTMVYPEPWCMPRlFTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGEVTevkLKDGRTLEADIVIVGVGGRPIISL 268
Cdd:COG0446 149 KVTLVERAPRLLGV-LDPEMAALLEEELREHGVELRLGETVVAIDGDDKVAVT---LTDGEEIPADLVVVAPGVRPNTEL 224

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 269 FKD-QVE-EEKGGLKTDGFFKTSLPDVYAIGDVATFPMKLYNEMRRVEHVDHARKSAEQAVKAIKAAEegnsiPEYDYLP 346
Cdd:COG0446 225 AKDaGLAlGERGWIKVDETLQTSDPDVYAAGDCAEVPHPVTGKTVYIPLASAANKQGRVAAENILGGP-----APFPGLG 299

                       330
                ....*....|....*.
gi 18414298 347 YFYSRAFDLSWQFYGD 362
Cdd:COG0446 300 TFISKVFDLCIASTGT 315
Pyr_redox_2 pfam07992
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 31-323 6.71e-53

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 400379 [Multi-domain]  Cd Length: 301  Bit Score: 179.05  E-value: 6.71e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298    31 KPGELAIISREQVPPYERPALSKGYIHlenkatlpnfyVAAGIGGERQFPQWYKEK---------GIELILGTEIVKADL 101
Cdd:pfam07992  22 LGGKVTLIEDEGTCPYGGCVLSKALLG-----------AAEAPEIASLWADLYKRKeevvkklnnGIEVLLGTEVVSIDP 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   102 AAKTL-----VSGTGQVFKYQTLLAATGSSVIRLsdfGVPGADAKNIFYLRELEDADYLAYAmetKEKGKAVVVGGGYIG 176
Cdd:pfam07992  91 GAKKVvleelVDGDGETITYDRLVIATGARPRLP---PIPGVELNVGFLVRTLDSAEALRLK---LLPKRVVVVGGGYIG 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   177 LELGAALKANNLDVTMVYPEPWcMPRLFTAGIASFYEGYYANKGINIVKGTVASGFttNSNGEVTEVKLKDGRTLEADIV 256
Cdd:pfam07992 165 VELAAALAKLGKEVTLIEALDR-LLRAFDEEISAALEKALEKNGVEVRLGTSVKEI--IGDGDGVEVILKDGTEIDADLV 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18414298   257 IVGVGGRPIISLFKDQ-VE-EEKGGLKTDGFFKTSLPDVYAIGDVAtfpmklyneMRRVEHVDHARKSA 323
Cdd:pfam07992 242 VVAIGRRPNTELLEAAgLElDERGGIVVDEYLRTSVPGIYAAGDCR---------VGGPELAQNAVAQG 301
PRK09754 PRK09754
phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional
 33-379 7.63e-33

phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional


Pssm-ID: 170080 [Multi-domain]  Cd Length: 396  Bit Score: 128.12  E-value: 7.63e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   33 GELAIISREQVPPYERPALSKGYihLENKATLPNFYVAAgiggerqfpQWYKEKGIELILGTEIVKADLAAKTLVSGTGQ 112
Cdd:PRK09754  29 GELHLFSDERHLPYERPPLSKSM--LLEDSPQLQQVLPA---------NWWQENNVHLHSGVTIKTLGRDTRELVLTNGE 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  113 VFKYQTLLAATGSSVIRLsdfgvPGADA--KNIFYLRELEDADYLAYAMetKEKGKAVVVGGGYIGLELGAALKANNLDV 190
Cdd:PRK09754  98 SWHWDQLFIATGAAARPL-----PLLDAlgERCFTLRHAGDAARLREVL--QPERSVVIVGAGTIGLELAASATQRRCKV 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  191 TMVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTvasGFTTNSNGEVTEVKLKDGRTLEADIVIVGVGGRpiislFK 270
Cdd:PRK09754 171 TVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNN---AIEHVVDGEKVELTLQSGETLQADVVIYGIGIS-----AN 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  271 DQVEEE-----KGGLKTDGFFKTSLPDVYAIGDVATfpMKLYN-EMRRVEHVDHARKSAEQAVKAIKAAEegnsiPEYDY 344
Cdd:PRK09754 243 DQLAREanldtANGIVIDEACRTCDPAIFAGGDVAI--TRLDNgALHRCESWENANNQAQIAAAAMLGLP-----LPLLP 315

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 18414298  345 LPYFYSRAFDLSWQFYGDNVGESVLFgDNDPESPK 379
Cdd:PRK09754 316 PPWFWSDQYSDNLQFIGDMRGDDWLC-RGNPETQK 349
nitri_red_nirB TIGR02374
nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen ...
 34-372 1.71e-31

nitrite reductase [NAD(P)H], large subunit; [Central intermediary metabolism, Nitrogen metabolism]


Pssm-ID: 162827 [Multi-domain]  Cd Length: 785  Bit Score: 127.64  E-value: 1.71e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298    34 ELAIISREQVPPYERPALSKgyiHLENKATLPNFYVAAGiggerqfpQWYKEKGIELILGTEIVKADLAAKTLVSGTGQV 113
Cdd:TIGR02374  26 EITIFGEEPHPNYNRILLSS---VLQGEADLDDITLNSK--------DWYEKHGITLYTGETVIQIDTDQKQVITDAGRT 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   114 FKYQTLLAATGSSVIRLSdfgVPGADAKNIFYLRELEDADYL-AYAMETKekgKAVVVGGGYIGLELGAALKANNLDVTM 192
Cdd:TIGR02374  95 LSYDKLILATGSYPFILP---IPGADKKGVYVFRTIEDLDAImAMAQRFK---KAAVIGGGLLGLEAAVGLQNLGMDVSV 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   193 VYPEPWCMPRLFTAGIASFYEGYYANKGINIV--KGTVASgfttNSNGEVTEVKLKDGRTLEADIVIVGVGGRPIISLFK 270
Cdd:TIGR02374 169 IHHAPGLMAKQLDQTAGRLLQRELEQKGLTFLleKDTVEI----VGATKADRIRFKDGSSLEADLIVMAAGIRPNDELAV 244

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   271 DQVEEEKGGLKTDGFFKTSLPDVYAIGDVATFPMKLYN------EMRRVEhVDH-----------ARKSAEQAVKAI--- 330
Cdd:TIGR02374 245 SAGIKVNRGIIVNDSMQTSDPDIYAVGECAEHNGRVYGlvaplyEQAKVL-ADHicgveceeyegSDLSAKLKLLGVdvw 323

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 18414298   331 -----KAAEEGNSIPEYDYLPYFYSRAFdlswqFYGDNVGESVLFGD 372
Cdd:TIGR02374 324 sagdaQETERTTSIKIYDEQKGIYKKLV-----LSDDKLLGAVLFGD 365
PRK09564 PRK09564
coenzyme A disulfide reductase; Reviewed
 80-301 5.16e-28

coenzyme A disulfide reductase; Reviewed


Pssm-ID: 181958 [Multi-domain]  Cd Length: 444  Bit Score: 115.14  E-value: 5.16e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   80 PQWYKEKGIELILGTEIVKADLAAKTLV---SGTGQVF--KYQTLLAATGSSVIRLSdfgVPGADAKNIFYLRELEDADY 154
Cdd:PRK09564  63 PEEFIKSGIDVKTEHEVVKVDAKNKTITvknLKTGSIFndTYDKLMIATGARPIIPP---IKNINLENVYTLKSMEDGLA 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  155 LAYAMETKEKGKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTVASGFTT 234
Cdd:PRK09564 140 LKELLKDEEIKNIVIIGAGFIGLEAVEAAKHLGKNVRIIQLEDRILPDSFDKEITDVMEEELRENGVELHLNEFVKSLIG 219

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18414298  235 NSNGEVTEVklkDGRTLEADIVIVGVGGRPIISLFKDQVEE--EKGGLKTDGFFKTSLPDVYAIGDVAT 301
Cdd:PRK09564 220 EDKVEGVVT---DKGEYEADVVIVATGVKPNTEFLEDTGLKtlKNGAIIVDEYGETSIENIYAAGDCAT 285
Ndh COG1252
NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];
84-344 1.52e-27

NADH dehydrogenase, FAD-containing subunit [Energy production and conversion];


Pssm-ID: 440864 [Multi-domain]  Cd Length: 386  Bit Score: 112.92  E-value: 1.52e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  84 KEKGIELILGtEIVKADLAAKTLVSGTGQVFKYQTLLAATGSsviRLSDFGVPGAdAKNIFYLRELEDADYL-------A 156
Cdd:COG1252  67 RRAGVRFIQG-EVTGIDPEARTVTLADGRTLSYDYLVIATGS---VTNFFGIPGL-AEHALPLKTLEDALALrerllaaF 141

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 157 YAMETKEKGKAVVVGGGYIGLELGAAL-------------KANNLDVTMVYPEPWCMPRlFTAGIASFYEGYYANKGINI 223
Cdd:COG1252 142 ERAERRRLLTIVVVGGGPTGVELAGELaellrkllrypgiDPDKVRITLVEAGPRILPG-LGEKLSEAAEKELEKRGVEV 220

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 224 VKGTVASGFTTNsngevtEVKLKDGRTLEADIVIV--GVGGRPIISLFKDQVEEeKGGLKTDGFFKT-SLPDVYAIGDVA 300
Cdd:COG1252 221 HTGTRVTEVDAD------GVTLEDGEEIPADTVIWaaGVKAPPLLADLGLPTDR-RGRVLVDPTLQVpGHPNVFAIGDCA 293

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....
gi 18414298 301 TFPMKLYNEMRRVEHvdHARKSAEQAVKAIKAAEEGNSIPEYDY 344
Cdd:COG1252 294 AVPDPDGKPVPKTAQ--AAVQQAKVLAKNIAALLRGKPLKPFRY 335
PRK06416 PRK06416
dihydrolipoamide dehydrogenase; Reviewed
 84-304 3.93e-23

dihydrolipoamide dehydrogenase; Reviewed


Pssm-ID: 235798 [Multi-domain]  Cd Length: 462  Bit Score: 100.99  E-value: 3.93e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   84 KEKGIELILGTeivkADLAAKTLVS----GTGQVFKYQTLLAATGSSVIRLsdfgvPG--ADAKNIFYLREledadylay 157
Cdd:PRK06416 103 KKNKVDIIRGE----AKLVDPNTVRvmteDGEQTYTAKNIILATGSRPREL-----PGieIDGRVIWTSDE--------- 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  158 AMETKE-KGKAVVVGGGYIGLELGAALKANNLDVTMVypEpwCMPRL---FTAGIASFYEGYYANKGINIVKGTVASGFT 233
Cdd:PRK06416 165 ALNLDEvPKSLVVIGGGYIGVEFASAYASLGAEVTIV--E--ALPRIlpgEDKEISKLAERALKKRGIKIKTGAKAKKVE 240

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 18414298  234 TNSNG-EVTEVKLKDGRTLEADIVIVGVGGRPIIS---LFKDQVEEEKGGLKTDGFFKTSLPDVYAIGDVATFPM 304
Cdd:PRK06416 241 QTDDGvTVTLEDGGKEETLEADYVLVAVGRRPNTEnlgLEELGVKTDRGFIEVDEQLRTNVPNIYAIGDIVGGPM 315
Lpd COG1249
Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex ...
 81-304 1.33e-22

Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase [Energy production and conversion]; Dihydrolipoamide dehydrogenase (E3) component of pyruvate/2-oxoglutarate dehydrogenase complex or glutathione oxidoreductase is part of the Pathway/BioSystem: Glycine cleavagePyruvate oxidation


Pssm-ID: 440861 [Multi-domain]  Cd Length: 456  Bit Score: 99.39  E-value: 1.33e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  81 QWYKEKGIELILGT-EIVkadlAAKTLVSGTGQVFKYQTLLAATGSSVIRLSdfgVPGADAKNIFYLREledadylayAM 159
Cdd:COG1249  99 ELLKKNGVDVIRGRaRFV----DPHTVEVTGGETLTADHIVIATGSRPRVPP---IPGLDEVRVLTSDE---------AL 162

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 160 ETKEKGK-AVVVGGGYIGLELGAALKANNLDVTMVYPepwcMPRL---FTAGIASFYEGYYANKGINIVKGTVASGFTTN 235
Cdd:COG1249 163 ELEELPKsLVVIGGGYIGLEFAQIFARLGSEVTLVER----GDRLlpgEDPEISEALEKALEKEGIDILTGAKVTSVEKT 238

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 18414298 236 SNGevTEVKLKDGR---TLEADIVIVGVGGRPIISLFKdqVEE------EKGGLKTDGFFKTSLPDVYAIGDVATFPM 304
Cdd:COG1249 239 GDG--VTVTLEDGGgeeAVEADKVLVATGRRPNTDGLG--LEAagveldERGGIKVDEYLRTSVPGIYAIGDVTGGPQ 312
lipoamide_DH TIGR01350
dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a ...
 83-347 2.69e-20

dihydrolipoamide dehydrogenase; This model describes dihydrolipoamide dehydrogenase, a flavoprotein that acts in a number of ways. It is the E3 component of dehydrogenase complexes for pyruvate, 2-oxoglutarate, 2-oxoisovalerate, and acetoin. It can also serve as the L protein of the glycine cleavage system. This family includes a few members known to have distinct functions (ferric leghemoglobin reductase and NADH:ferredoxin oxidoreductase) but that may be predicted by homology to act as dihydrolipoamide dehydrogenase as well. The motif GGXCXXXGCXP near the N-terminus contains a redox-active disulfide.


Pssm-ID: 273568 [Multi-domain]  Cd Length: 460  Bit Score: 92.71  E-value: 2.69e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298    83 YKEKGIELILGTEIVKADLAAKTLVSGTGQVFKYQTLLAATGSSVIRLSdfGVPGADAKNIFYLREledadylayAMETK 162
Cdd:TIGR01350  99 LKKNKVTVIKGEAKFLDPGTVSVTGENGEETLEAKNIIIATGSRPRSLP--GPFDFDGKVVITSTG---------ALNLE 167

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   163 EK-GKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPrLFTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGEVT 241
Cdd:TIGR01350 168 EVpESLVIIGGGVIGIEFASIFASLGSKVTVIEMLDRILP-GEDAEVSKVLQKALKKKGVKILTNTKVTAVEKNDDQVTY 246

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   242 EVKLKDGRTLEADIVIVGVGGRP---IISLFKDQVE-EEKGGLKTDGFFKTSLPDVYAIGDVATFPMklynemrrVEHVd 317
Cdd:TIGR01350 247 ENKGGETETLTGEKVLVAVGRKPnteGLGLEKLGVElDERGRIVVDEYMRTNVPGIYAIGDVIGGPM--------LAHV- 317

                         250       260       270
                  ....*....|....*....|....*....|
gi 18414298   318 hARKSAEQAVKAIkAAEEGNSIpEYDYLPY 347
Cdd:TIGR01350 318 -ASHEGIVAAENI-AGKEPAHI-DYDAVPS 344
PRK13512 PRK13512
coenzyme A disulfide reductase; Provisional
 81-301 4.41e-17

coenzyme A disulfide reductase; Provisional


Pssm-ID: 184103 [Multi-domain]  Cd Length: 438  Bit Score: 82.91  E-value: 4.41e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   81 QWYKEKGIELILGTEIVKADLAAKTLV---SGTGQVFK--YQTLLAATGSSVIRLsdfgvpGADAKNIFYLRELEDADYL 155
Cdd:PRK13512  66 KFYDRKQITVKTYHEVIAINDERQTVTvlnRKTNEQFEesYDKLILSPGASANSL------GFESDITFTLRNLEDTDAI 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  156 AYAMETKEKGKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWC---MPRLFTAGIASFYEG----YYANKGINIVKGtv 228
Cdd:PRK13512 140 DQFIKANQVDKALVVGAGYISLEVLENLYERGLHPTLIHRSDKInklMDADMNQPILDELDKreipYRLNEEIDAING-- 217

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 18414298  229 asgfttnsngevTEVKLKDGRTLEADIVIVGVGGRPIISLFKDQ--VEEEKGGLKTDGFFKTSLPDVYAIGDVAT 301
Cdd:PRK13512 218 ------------NEVTFKSGKVEHYDMIIEGVGTHPNSKFIESSniKLDDKGFIPVNDKFETNVPNIYAIGDIIT 280
TrxB COG0492
Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];
87-306 2.18e-16

Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440258 [Multi-domain]  Cd Length: 305  Bit Score: 79.39  E-value: 2.18e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  87 GIELILgTEIVKADLA--AKTLVSGTGQVFKYQTLLAATGSSVIRLsdfGVPGADA---KNIFYLrelEDADYLAYamet 161
Cdd:COG0492  71 GAEILL-EEVTSVDKDdgPFRVTTDDGTEYEAKAVIIATGAGPRKL---GLPGEEEfegRGVSYC---ATCDGFFF---- 139

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 162 keKGKAV-VVGGGYIGLELgaalkANNL-----DVTMVYP--EPWCMP----RLFtagiasfyegyyANKGINIVKGTVA 229
Cdd:COG0492 140 --RGKDVvVVGGGDSALEE-----ALYLtkfasKVTLIHRrdELRASKilveRLR------------ANPKIEVLWNTEV 200

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 230 SGFttNSNGEVTEVKLKDGRT-----LEADIVIVGVGGRPIISLFKDQVEE--EKGGLKTDGFFKTSLPDVYAIGDVATF 302
Cdd:COG0492 201 TEI--EGDGRVEGVTLKNVKTgeekeLEVDGVFVAIGLKPNTELLKGLGLEldEDGYIVVDEDMETSVPGVFAAGDVRDY 278


                ....
gi 18414298 303 PMKL 306
Cdd:COG0492 279 KYRQ 282
PRK06292 PRK06292
dihydrolipoamide dehydrogenase; Validated
 84-304 3.62e-15

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235774 [Multi-domain]  Cd Length: 460  Bit Score: 77.14  E-value: 3.62e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   84 KEKGIELILGT-EIVkadlAAKTLVSGtGQVFKYQTLLAATGSSVIRlsdfgVPGADaknifylrELEDADYLAY--AME 160
Cdd:PRK06292 103 KKPKIDKIKGTaRFV----DPNTVEVN-GERIEAKNIVIATGSRVPP-----IPGVW--------LILGDRLLTSddAFE 164

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  161 TKEKGKAV-VVGGGYIGLELGAALKANNLDVTMVYPEPWCMPrLFTAGIASFYEGYYAnKGINIVKGTVASGFTTNSNGE 239
Cdd:PRK06292 165 LDKLPKSLaVIGGGVIGLELGQALSRLGVKVTVFERGDRILP-LEDPEVSKQAQKILS-KEFKIKLGAKVTSVEKSGDEK 242

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  240 VTEVKLKDG-RTLEADIVIVGVGGRP---IISLFKDQVE-EEKGGLKTDGFFKTSLPDVYAIGDVATFPM 304
Cdd:PRK06292 243 VEELEKGGKtETIEADYVLVATGRRPntdGLGLENTGIElDERGRPVVDEHTQTSVPGIYAAGDVNGKPP 312
PRK14989 PRK14989
nitrite reductase subunit NirD; Provisional
 80-318 9.24e-15

nitrite reductase subunit NirD; Provisional


Pssm-ID: 184951 [Multi-domain]  Cd Length: 847  Bit Score: 76.70  E-value: 9.24e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   80 PQWYKEKGIELILGTEIVKADLAAKTLVSGTGQVFKYQTLLAATGSSVIrlsdfgVP---GADAKNIFYLRELEDADyla 156
Cdd:PRK14989  66 EGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFYDKLIMATGSYPW------IPpikGSETQDCFVYRTIEDLN--- 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  157 yAME--TKEKGKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTVASGFTT 234
Cdd:PRK14989 137 -AIEacARRSKRGAVVGGGLLGLEAAGALKNLGVETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQ 215

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  235 NSNGEVTEVKLKDGRTLEADIVIVGVGGRPIISLFKdQVE---EEKGGLKTDGFFKTSLPDVYAIGDVATFPMKLYN--- 308
Cdd:PRK14989 216 EGVEARKTMRFADGSELEVDFIVFSTGIRPQDKLAT-QCGlavAPRGGIVINDSCQTSDPDIYAIGECASWNNRVFGlva 294

                        250
                 ....*....|...
gi 18414298  309 ---EMRRVEhVDH 318
Cdd:PRK14989 295 pgyKMAQVA-VDH 306
GltD COG0493
NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport ...
 84-301 1.09e-14

NADPH-dependent glutamate synthase beta chain or related oxidoreductase [Amino acid transport and metabolism, General function prediction only]; NADPH-dependent glutamate synthase beta chain or related oxidoreductase is part of the Pathway/BioSystem: Glutamine biosynthesis


Pssm-ID: 440259 [Multi-domain]  Cd Length: 434  Bit Score: 75.56  E-value: 1.09e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  84 KEKGIELILGTEIVKaDLAAKTLVSgtgqvfKYQTLLAATGSSVIRlsDFGVPGADAKNIF----YLRELEDADYLAYAM 159
Cdd:COG0493 182 EALGVEFRTNVEVGK-DITLDELLE------EFDAVFLATGAGKPR--DLGIPGEDLKGVHsamdFLTAVNLGEAPDTIL 252

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 160 EtkeKGK-AVVVGGGYIG-------LELGAAlkannlDVTMVYPEPW-CMPrlftagiASFYEGYYA-NKGINIVKGTVA 229
Cdd:COG0493 253 A---VGKrVVVIGGGNTAmdcartaLRLGAE------SVTIVYRRTReEMP-------ASKEEVEEAlEEGVEFLFLVAP 316

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298 230 SGFTTNSNGEVTEVKL---------KDGR-----------TLEADIVIVGVGGRPIISLFKDQVE---EEKGGLKTD-GF 285
Cdd:COG0493 317 VEIIGDENGRVTGLECvrmelgepdESGRrrpvpiegsefTLPADLVILAIGQTPDPSGLEEELGlelDKRGTIVVDeET 396

                       250
                ....*....|....*.
gi 18414298 286 FKTSLPDVYAIGDVAT 301
Cdd:COG0493 397 YQTSLPGVFAGGDAVR 412
PRK06116 PRK06116
glutathione reductase; Validated
 87-299 4.18e-14

glutathione reductase; Validated


Pssm-ID: 235701 [Multi-domain]  Cd Length: 450  Bit Score: 73.65  E-value: 4.18e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   87 GIELILGteivKADLAAKTLVSGTGQVFKYQTLLAATGSSVIRLSdfgVPGA----DAKNIFYLRELEDadylayametk 162
Cdd:PRK06116 107 GVDLIEG----FARFVDAHTVEVNGERYTADHILIATGGRPSIPD---IPGAeygiTSDGFFALEELPK----------- 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  163 ekgKAVVVGGGYIGLELGAALKANNLDVTMVY--PEPWcmpRLFTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGEV 240
Cdd:PRK06116 169 ---RVAVVGAGYIAVEFAGVLNGLGSETHLFVrgDAPL---RGFDPDIRETLVEEMEKKGIRLHTNAVPKAVEKNADGSL 242

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 18414298  241 TeVKLKDGRTLEADIVIVGVGGRPI---ISLFKDQVE-EEKGGLKTDGFFKTSLPDVYAIGDV 299
Cdd:PRK06116 243 T-LTLEDGETLTVDCLIWAIGREPNtdgLGLENAGVKlNEKGYIIVDEYQNTNVPGIYAVGDV 304
PRK04965 PRK04965
NADH:flavorubredoxin reductase NorW;
88-300 4.79e-13

NADH:flavorubredoxin reductase NorW;


Pssm-ID: 179902 [Multi-domain]  Cd Length: 377  Bit Score: 69.95  E-value: 4.79e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   88 IELILGTEIVKADLAAKTLVSGtGQVFKYQTLLAATGSSVIRLSdfgVPGADAknIFYLRELEDadYLAYAMETKEKGKA 167
Cdd:PRK04965  73 LRLFPHTWVTDIDAEAQVVKSQ-GNQWQYDKLVLATGASAFVPP---IPGREL--MLTLNSQQE--YRAAETQLRDAQRV 144

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  168 VVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPRLFTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGEVteVKLKD 247
Cdd:PRK04965 145 LVVGGGLIGTELAMDLCRAGKAVTLVDNAASLLASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGIR--ATLDS 222

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 18414298  248 GRTLEADIVIVGVGGRPIISLFKDQVEEEKGGLKTDGFFKTSLPDVYAIGDVA 300
Cdd:PRK04965 223 GRSIEVDAVIAAAGLRPNTALARRAGLAVNRGIVVDSYLQTSAPDIYALGDCA 275
Pyr_redox pfam00070
Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II ...
 166-248 5.93e-13

Pyridine nucleotide-disulphide oxidoreductase; This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.


Pssm-ID: 425450 [Multi-domain]  Cd Length: 80  Bit Score: 63.76  E-value: 5.93e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   166 KAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPrLFTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGEVteVKL 245
Cdd:pfam00070   1 RVVVVGGGYIGLELAGALARLGSKVTVVERRDRLLP-GFDPEIAKILQEKLEKNGIEFLLNTTVEAIEGNGDGVV--VVL 77


                  ...
gi 18414298   246 KDG 248
Cdd:pfam00070  78 TDG 80
PRK06327 PRK06327
dihydrolipoamide dehydrogenase; Validated
 107-304 2.03e-11

dihydrolipoamide dehydrogenase; Validated


Pssm-ID: 235779 [Multi-domain]  Cd Length: 475  Bit Score: 65.72  E-value: 2.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  107 VSGTG-QVFKYQTLLAATGSSVIRLSdfGVPgADAKNIfylreLEDADYLAYameTKEKGKAVVVGGGYIGLELGAALKA 185
Cdd:PRK06327 136 VTGEDeTVITAKHVIIATGSEPRHLP--GVP-FDNKII-----LDNTGALNF---TEVPKKLAVIGAGVIGLELGSVWRR 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  186 NNLDVTMVYpepwCMPRLFTA---GIASFYEGYYANKGINIVKGTVASGFTTNSNGEVTEVKLKDG--RTLEADIVIVGV 260
Cdd:PRK06327 205 LGAEVTILE----ALPAFLAAadeQVAKEAAKAFTKQGLDIHLGVKIGEIKTGGKGVSVAYTDADGeaQTLEVDKLIVSI 280

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 18414298  261 GGRP-IISLFKDQV---EEEKGGLKTDGFFKTSLPDVYAIGDVATFPM 304
Cdd:PRK06327 281 GRVPnTDGLGLEAVglkLDERGFIPVDDHCRTNVPNVYAIGDVVRGPM 328
trypano_reduc TIGR01423
trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of ...
 119-299 5.80e-11

trypanothione-disulfide reductase; Trypanothione, a glutathione-modified derivative of spermidine, is (in its reduced form) an important antioxidant found in trypanosomatids (Crithidia, Leishmania, Trypanosoma). This model describes trypanothione reductase, a possible antitrypanosomal drug target closely related to some forms of glutathione reductase.


Pssm-ID: 200098 [Multi-domain]  Cd Length: 486  Bit Score: 64.22  E-value: 5.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   119 LLAATGSSVIRLsdfGVPGAD----AKNIFYLREledadylayametkEKGKAVVVGGGYIGLELGA---ALKANNLDVT 191
Cdd:TIGR01423 155 ILLATGSWPQML---GIPGIEhcisSNEAFYLDE--------------PPRRVLTVGGGFISVEFAGifnAYKPRGGKVT 217

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   192 MVYPEPWCMpRLFTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGEvTEVKLKDGRTLEADIVIVGVGGRP---IISL 268
Cdd:TIGR01423 218 LCYRNNMIL-RGFDSTLRKELTKQLRANGINIMTNENPAKVTLNADGS-KHVTFESGKTLDVDVVMMAIGRVPrtqTLQL 295

                         170       180       190
                  ....*....|....*....|....*....|..
gi 18414298   269 FKDQVE-EEKGGLKTDGFFKTSLPDVYAIGDV 299
Cdd:TIGR01423 296 DKVGVElTKKGAIQVDEFSRTNVPNIYAIGDV 327
PLN02507 PLN02507
glutathione reductase
 87-299 6.63e-11

glutathione reductase


Pssm-ID: 215281 [Multi-domain]  Cd Length: 499  Bit Score: 64.07  E-value: 6.63e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   87 GIELILGT-EIVKADLAAKTLVSGTGQVFKYQTLLAATGSSVIRLSdfgVPGadaknifylRELEDADYLAYAMETKEKg 165
Cdd:PLN02507 138 GVKLYEGEgKIVGPNEVEVTQLDGTKLRYTAKHILIATGSRAQRPN---IPG---------KELAITSDEALSLEELPK- 204

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  166 KAVVVGGGYIGLELGAALKANNLDVTMVYPEPwcMP-RLFT----AGIASFYEGyyanKGINIVKGTVASGFTTNSNGev 240
Cdd:PLN02507 205 RAVVLGGGYIAVEFASIWRGMGATVDLFFRKE--LPlRGFDdemrAVVARNLEG----RGINLHPRTNLTQLTKTEGG-- 276

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 18414298  241 TEVKLKDGRTLEADIVIVGVGGRPI---ISLFKDQVEEEK-GGLKTDGFFKTSLPDVYAIGDV 299
Cdd:PLN02507 277 IKVITDHGEEFVADVVLFATGRAPNtkrLNLEAVGVELDKaGAVKVDEYSRTNIPSIWAIGDV 339
PRK07846 PRK07846
mycothione reductase; Reviewed
 102-315 2.26e-10

mycothione reductase; Reviewed


Pssm-ID: 181142 [Multi-domain]  Cd Length: 451  Bit Score: 62.28  E-value: 2.26e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  102 AAKTLVSGTGQVFKYQTLLAATGS-----SVIRLSdfGVPGADAKNIFYLRELedadylayametkeKGKAVVVGGGYIG 176
Cdd:PRK07846 115 GPKTLRTGDGEEITADQVVIAAGSrpvipPVIADS--GVRYHTSDTIMRLPEL--------------PESLVIVGGGFIA 178

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  177 LELGAALKANNLDVTMVYPEPwCMPRLFTAGIA-SFYEgyYANKGINIVKGTVASGFTTNSNGevTEVKLKDGRTLEADI 255
Cdd:PRK07846 179 AEFAHVFSALGVRVTVVNRSG-RLLRHLDDDISeRFTE--LASKRWDVRLGRNVVGVSQDGSG--VTLRLDDGSTVEADV 253

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 18414298  256 VIVGVGGRP---IISLFKDQVE-EEKGGLKTDGFFKTSLPDVYAIGDVAT-FPMK-LYN-EMRRVEH 315
Cdd:PRK07846 254 LLVATGRVPngdLLDAAAAGVDvDEDGRVVVDEYQRTSAEGVFALGDVSSpYQLKhVANhEARVVQH 320
PRK11749 PRK11749
dihydropyrimidine dehydrogenase subunit A; Provisional
 81-301 3.71e-10

dihydropyrimidine dehydrogenase subunit A; Provisional


Pssm-ID: 236967 [Multi-domain]  Cd Length: 457  Bit Score: 61.73  E-value: 3.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   81 QWYKEKGIELILGTEIVKaDLAAKTLVSGtgqvfkYQTLLAATGSSVIRlsDFGVPGADAKNIF----YLRELEDADYLa 156
Cdd:PRK11749 198 ERLLKLGVEIRTNTEVGR-DITLDELRAG------YDAVFIGTGAGLPR--FLGIPGENLGGVYsavdFLTRVNQAVAD- 267

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  157 yamETKEKGKAVVV-GGGYIG-------LELGAAlkannlDVTMVY---PEPwcMPrlftagiASFYEGYYA-NKGINIV 224
Cdd:PRK11749 268 ---YDLPVGKRVVViGGGNTAmdaartaKRLGAE------SVTIVYrrgREE--MP-------ASEEEVEHAkEEGVEFE 329

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  225 KGTVASGFTTNSNGeVTEVKL---------KDGR----------TLEADIVIVGVGGRPIISLFKDQVEEE---KGGLKT 282
Cdd:PRK11749 330 WLAAPVEILGDEGR-VTGVEFvrmelgepdASGRrrvpiegsefTLPADLVIKAIGQTPNPLILSTTPGLElnrWGTIIA 408

                        250       260
                 ....*....|....*....|
gi 18414298  283 D-GFFKTSLPDVYAIGDVAT 301
Cdd:PRK11749 409 DdETGRTSLPGVFAGGDIVT 428
PRK06370 PRK06370
FAD-containing oxidoreductase;
81-299 9.20e-10

FAD-containing oxidoreductase;


Pssm-ID: 235787 [Multi-domain]  Cd Length: 463  Bit Score: 60.22  E-value: 9.20e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   81 QWYKE-KGIELILGTeivkADLAAKTLVSGTGQVFKYQTLLAATGSsviRLSDFGVPGadaknifylreLEDADYLAYA- 158
Cdd:PRK06370 102 QWLRGlEGVDVFRGH----ARFESPNTVRVGGETLRAKRIFINTGA---RAAIPPIPG-----------LDEVGYLTNEt 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  159 -METKEK-GKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPRlFTAGIASFYEGYYANKGINIVKGTVASGFTTNS 236
Cdd:PRK06370 164 iFSLDELpEHLVIIGGGYIGLEFAQMFRRFGSEVTVIERGPRLLPR-EDEDVAAAVREILEREGIDVRLNAECIRVERDG 242

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 18414298  237 NGEVTEVKLKDGR-TLEADIVIVGVGGRPIIS---LFKDQVE-EEKGGLKTDGFFKTSLPDVYAIGDV 299
Cdd:PRK06370 243 DGIAVGLDCNGGApEITGSHILVAVGRVPNTDdlgLEAAGVEtDARGYIKVDDQLRTTNPGIYAAGDC 310
PTZ00318 PTZ00318
NADH dehydrogenase-like protein; Provisional
 113-301 1.01e-07

NADH dehydrogenase-like protein; Provisional


Pssm-ID: 185553 [Multi-domain]  Cd Length: 424  Bit Score: 54.00  E-value: 1.01e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  113 VFKYQTLLAATGSsviRLSDFGVPGADaKNIFYLRE--------------LEDADYLAYAMETKEK-GKAVVVGGGYIGL 177
Cdd:PTZ00318 111 SVPYDKLVVAHGA---RPNTFNIPGVE-ERAFFLKEvnhargirkrivqcIERASLPTTSVEERKRlLHFVVVGGGPTGV 186

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  178 ELGAALkaNNL---DVTMVYPE--PWCMPRLFTAG--IASFYEGYYANKGINIVKgtvASGFTTNSNGEVTEVK-----L 245
Cdd:PTZ00318 187 EFAAEL--ADFfrdDVRNLNPElvEECKVTVLEAGseVLGSFDQALRKYGQRRLR---RLGVDIRTKTAVKEVLdkevvL 261

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 18414298  246 KDGRTLEADIVI--VGVGGRPIISLFKDQvEEEKGGLKTDGFFKTS-LPDVYAIGDVAT 301
Cdd:PTZ00318 262 KDGEVIPTGLVVwsTGVGPGPLTKQLKVD-KTSRGRISVDDHLRVKpIPNVFALGDCAA 319
gltD PRK12810
glutamate synthase subunit beta; Reviewed
 84-324 1.85e-07

glutamate synthase subunit beta; Reviewed


Pssm-ID: 237213 [Multi-domain]  Cd Length: 471  Bit Score: 53.24  E-value: 1.85e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   84 KEKGIELILGTEIVKaDLAAKTLVSgtgqvfKYQTLLAATGSSVIRlsDFGVPGADAKNIFylreleDA-DYLA----YA 158
Cdd:PRK12810 204 EAEGIEFRTNVEVGK-DITAEELLA------EYDAVFLGTGAYKPR--DLGIPGRDLDGVH------FAmDFLIqntrRV 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  159 METKE------KGKAVVV-GGGYIGLE-LGAALKANNLDVTM--VYPEP----------WCMPRLFTAGiasfyegyYAN 218
Cdd:PRK12810 269 LGDETepfisaKGKHVVViGGGDTGMDcVGTAIRQGAKSVTQrdIMPMPpsrrnknnpwPYWPMKLEVS--------NAH 340

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  219 K-GINIVKGTVASGFTTnSNGEVTEVK-----LKDG---------RTLEADIVIVGVGGR-PIISLFKD-QVE-EEKGGL 280
Cdd:PRK12810 341 EeGVEREFNVQTKEFEG-ENGKVTGVKvvrteLGEGdfepvegseFVLPADLVLLAMGFTgPEAGLLAQfGVElDERGRV 419

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 18414298  281 K-TDGFFKTSLPDVYAIGDvatfpmklyneMRR-----VEHVDHARKSAE 324
Cdd:PRK12810 420 AaPDNAYQTSNPKVFAAGD-----------MRRgqslvVWAIAEGRQAAR 458
PRK07845 PRK07845
flavoprotein disulfide reductase; Reviewed
 87-299 2.51e-07

flavoprotein disulfide reductase; Reviewed


Pssm-ID: 236112 [Multi-domain]  Cd Length: 466  Bit Score: 52.55  E-value: 2.51e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   87 GIELILGT-EIVKADLAAK----TLVSGTGQVFKYQTLLAATGSSVIRLsdfgvPGA--DAKNIFYLRELEDADylayam 159
Cdd:PRK07845 106 GVRVIAGRgRLIDPGLGPHrvkvTTADGGEETLDADVVLIATGASPRIL-----PTAepDGERILTWRQLYDLD------ 174

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  160 ETKEKgkAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPRLfTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGe 239
Cdd:PRK07845 175 ELPEH--LIVVGSGVTGAEFASAYTELGVKVTLVSSRDRVLPGE-DADAAEVLEEVFARRGMTVLKRSRAESVERTGDG- 250

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 18414298  240 vTEVKLKDGRTLEADIVIVGVGGRPI---ISLFKDQVEEEKGG-LKTDGFFKTSLPDVYAIGDV 299
Cdd:PRK07845 251 -VVVTLTDGRTVEGSHALMAVGSVPNtagLGLEEAGVELTPSGhITVDRVSRTSVPGIYAAGDC 313
TGR TIGR01438
thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member ...
 95-300 3.36e-07

thioredoxin and glutathione reductase selenoprotein; This homodimeric, FAD-containing member of the pyridine nucleotide disulfide oxidoreductase family contains a C-terminal motif Cys-SeCys-Gly, where SeCys is selenocysteine encoded by TGA (in some sequence reports interpreted as a stop codon). In some members of this subfamily, Cys-SeCys-Gly is replaced by Cys-Cys-Gly. The reach of the selenium atom at the C-term arm of the protein is proposed to allow broad substrate specificity.


Pssm-ID: 273624 [Multi-domain]  Cd Length: 484  Bit Score: 52.16  E-value: 3.36e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298    95 EIVKADLAAKTLVSGTGQVFKYQTLLAATGssvIRLSDFGVPGADAKNIfylrELEDADYLAYAmetkeKGKAVVVGGGY 174
Cdd:TIGR01438 123 EFVDKHRIKATNKKGKEKIYSAERFLIATG---ERPRYPGIPGAKELCI----TSDDLFSLPYC-----PGKTLVVGASY 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   175 IGLELGAALKANNLDVT-MVYPEPWcmpRLFTAGIASFYEGYYANKGINIVKGTVASGFT-TNSNGEVTEVKLKDGRTLE 252
Cdd:TIGR01438 191 VALECAGFLAGIGLDVTvMVRSILL---RGFDQDCANKVGEHMEEHGVKFKRQFVPIKVEqIEAKVLVEFTDSTNGIEEE 267

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 18414298   253 ADIVIVGVGGRPII-SLFKD----QVEEEKGGLKTDGFFKTSLPDVYAIGDVA 300
Cdd:TIGR01438 268 YDTVLLAIGRDACTrKLNLEnvgvKINKKTGKIPADEEEQTNVPYIYAVGDIL 320
PRK07251 PRK07251
FAD-containing oxidoreductase;
86-299 5.75e-07

FAD-containing oxidoreductase;


Pssm-ID: 180907 [Multi-domain]  Cd Length: 438  Bit Score: 51.67  E-value: 5.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298   86 KGIELILGTEivKADLAAKTLVSGTGQVfkyqtllaatgsSVIrlsdFGVPG-ADAKNIFYLRELEdadylayAMETKEK 164
Cdd:PRK07251 104 KVIEVQAGDE--KIELTAETIVINTGAV------------SNV----LPIPGlADSKHVYDSTGIQ-------SLETLPE 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  165 gKAVVVGGGYIGLELgAALKAN-NLDVTMVYPEPWCMPRlFTAGIASFYEGYYANKGINIVKGtVASGFTTNSNGEVteV 243
Cdd:PRK07251 159 -RLGIIGGGNIGLEF-AGLYNKlGSKVTVLDAASTILPR-EEPSVAALAKQYMEEDGITFLLN-AHTTEVKNDGDQV--L 232

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  244 KLKDGRTLEADIVIVGVGGRPIISLFK----DQVEEEKGGLKTDGFFKTSLPDVYAIGDV 299
Cdd:PRK07251 233 VVTEDETYRFDALLYATGRKPNTEPLGlentDIELTERGAIKVDDYCQTSVPGVFAVGDV 292
PTZ00058 PTZ00058
glutathione reductase; Provisional
 162-298 1.22e-05

glutathione reductase; Provisional


Pssm-ID: 185420 [Multi-domain]  Cd Length: 561  Bit Score: 47.69  E-value: 1.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  162 KEKGKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMpRLFTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGEVT 241
Cdd:PTZ00058 235 KEAKRIGIAGSGYIAVELINVVNRLGAESYIFARGNRLL-RKFDETIINELENDMKKNNINIITHANVEEIEKVKEKNLT 313

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  242 EVKLKDGRTLEADIVIVGVGGRP---IISLFKDQVEEEKGGLKTDGFFKTSLPDVYAIGD 298
Cdd:PTZ00058 314 IYLSDGRKYEHFDYVIYCVGRSPnteDLNLKALNIKTPKGYIKVDDNQRTSVKHIYAVGD 373
PRK05249 PRK05249
Si-specific NAD(P)(+) transhydrogenase;
168-303 4.18e-05

Si-specific NAD(P)(+) transhydrogenase;


Pssm-ID: 235373 [Multi-domain]  Cd Length: 461  Bit Score: 45.53  E-value: 4.18e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  168 VVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPRLFTAGIASFYegyYA--NKGINIVKGTVASGFTTNSNGevTEVKL 245
Cdd:PRK05249 179 IIYGAGVIGCEYASIFAALGVKVTLINTRDRLLSFLDDEISDALS---YHlrDSGVTIRHNEEVEKVEGGDDG--VIVHL 253

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18414298  246 KDGRTLEADIVIVGVG--------GRPIISLFKDqveeEKGGLKTDGFFKTSLPDVYAIGDVATFP 303
Cdd:PRK05249 254 KSGKKIKADCLLYANGrtgntdglNLENAGLEAD----SRGQLKVNENYQTAVPHIYAVGDVIGFP 315
PTZ00052 PTZ00052
thioredoxin reductase; Provisional
 162-346 6.74e-04

thioredoxin reductase; Provisional


Pssm-ID: 185416 [Multi-domain]  Cd Length: 499  Bit Score: 41.73  E-value: 6.74e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  162 KEKGKAVVVGGGYIGLELGAALKANNLDVTMVYPEpwCMPRLFTAGIASFYEGYYANKGINIVKGTVASGFTTNSngEVT 241
Cdd:PTZ00052 180 KDPGKTLIVGASYIGLETAGFLNELGFDVTVAVRS--IPLRGFDRQCSEKVVEYMKEQGTLFLEGVVPINIEKMD--DKI 255

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  242 EVKLKDGRTLEADIVIVGVGGRPIISLFKDQ---VEEEKGGLKTDGFFKTSLPDVYAIGDVATfpmklynemrrvehvdh 318
Cdd:PTZ00052 256 KVLFSDGTTELFDTVLYATGRKPDIKGLNLNaigVHVNKSNKIIAPNDCTNIPNIFAVGDVVE----------------- 318

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 18414298  319 arKSAEQAVKAIKAAE--------EGNSIPEYDYLP 346
Cdd:PTZ00052 319 --GRPELTPVAIKAGIllarrlfkQSNEFIDYTFIP 352
PRK08010 PRK08010
pyridine nucleotide-disulfide oxidoreductase; Provisional
 165-299 2.16e-03

pyridine nucleotide-disulfide oxidoreductase; Provisional


Pssm-ID: 181196 [Multi-domain]  Cd Length: 441  Bit Score: 40.38  E-value: 2.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18414298  165 GKAVVVGGGYIGLELGAALKANNLDVTMVYPEPWCMPRLfTAGIASFYEGYYANKGINIVKGTVASGFTTNSNGevTEVK 244
Cdd:PRK08010 159 GHLGILGGGYIGVEFASMFANFGSKVTILEAASLFLPRE-DRDIADNIATILRDQGVDIILNAHVERISHHENQ--VQVH 235

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 18414298  245 LKDGRTLeADIVIVGVGGRPIISLFKDQ----VEEEKGGLKTDGFFKTSLPDVYAIGDV 299
Cdd:PRK08010 236 SEHAQLA-VDALLIASGRQPATASLHPEnagiAVNERGAIVVDKYLHTTADNIWAMGDV 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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