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Conserved domains on  [gi|19115767|ref|NP_594855|]
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Spg1-binding protein Etd1 [Schizosaccharomyces pombe]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Etd1 pfam20162
Septation protein etd1; This family includes the Septation protein etd1 from ...
 238-335 1.24e-51

Septation protein etd1; This family includes the Septation protein etd1 from Schizosaccharomyces pombe, which activates the GTPase Spg1 to trigger signaling through the septum initiation network (SIN) pathway and onset of cytokinesis. The proper regulation of Etd1 is crucial for both activation of Spg1 in anaphase and inactivation of Spg1 when cytokinesis is complete. It was suggested that Etd1 is the functional homolog of budding yeast Lte1 as they have the same function but a very low sequence similarity.


:

Pssm-ID: 437994  Cd Length: 98  Bit Score: 167.79  E-value: 1.24e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115767   238 HINNDSSDIRFSSRCDLFADDADSDWEQDFNVKFDSPLIIPETVNSAGHTVREQLFEVKEFTRSIKDLKDLYEKANSKDI 317
Cdd:pfam20162   1 HIRNDSSDIRFSSRCDLFADDADEDWDDDFDVKFDSPLIIPETINSAQHTVRGHLGEVREFARSVKDLKDLYEKANSKDV 80

                          90
                  ....*....|....*...
gi 19115767   318 YDKDSEILGEAKAILRLA 335
Cdd:pfam20162  81 YDKDSEILGDAKAILRLA 98
 
Name Accession Description Interval E-value
Etd1 pfam20162
Septation protein etd1; This family includes the Septation protein etd1 from ...
 238-335 1.24e-51

Septation protein etd1; This family includes the Septation protein etd1 from Schizosaccharomyces pombe, which activates the GTPase Spg1 to trigger signaling through the septum initiation network (SIN) pathway and onset of cytokinesis. The proper regulation of Etd1 is crucial for both activation of Spg1 in anaphase and inactivation of Spg1 when cytokinesis is complete. It was suggested that Etd1 is the functional homolog of budding yeast Lte1 as they have the same function but a very low sequence similarity.


Pssm-ID: 437994  Cd Length: 98  Bit Score: 167.79  E-value: 1.24e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115767   238 HINNDSSDIRFSSRCDLFADDADSDWEQDFNVKFDSPLIIPETVNSAGHTVREQLFEVKEFTRSIKDLKDLYEKANSKDI 317
Cdd:pfam20162   1 HIRNDSSDIRFSSRCDLFADDADEDWDDDFDVKFDSPLIIPETINSAQHTVRGHLGEVREFARSVKDLKDLYEKANSKDV 80

                          90
                  ....*....|....*...
gi 19115767   318 YDKDSEILGEAKAILRLA 335
Cdd:pfam20162  81 YDKDSEILGDAKAILRLA 98
 
Name Accession Description Interval E-value
Etd1 pfam20162
Septation protein etd1; This family includes the Septation protein etd1 from ...
 238-335 1.24e-51

Septation protein etd1; This family includes the Septation protein etd1 from Schizosaccharomyces pombe, which activates the GTPase Spg1 to trigger signaling through the septum initiation network (SIN) pathway and onset of cytokinesis. The proper regulation of Etd1 is crucial for both activation of Spg1 in anaphase and inactivation of Spg1 when cytokinesis is complete. It was suggested that Etd1 is the functional homolog of budding yeast Lte1 as they have the same function but a very low sequence similarity.


Pssm-ID: 437994  Cd Length: 98  Bit Score: 167.79  E-value: 1.24e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19115767   238 HINNDSSDIRFSSRCDLFADDADSDWEQDFNVKFDSPLIIPETVNSAGHTVREQLFEVKEFTRSIKDLKDLYEKANSKDI 317
Cdd:pfam20162   1 HIRNDSSDIRFSSRCDLFADDADEDWDDDFDVKFDSPLIIPETINSAQHTVRGHLGEVREFARSVKDLKDLYEKANSKDV 80

                          90
                  ....*....|....*...
gi 19115767   318 YDKDSEILGEAKAILRLA 335
Cdd:pfam20162  81 YDKDSEILGDAKAILRLA 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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